psnGPCR

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Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	NT.L54	NT.L56	9.69	No	No	0	7	6
2	NT.I78	NT.L54	5.71	No	No	0	8	7
3	NT.E79	NT.S55	10.06	No	No	0	5	4
4	NT.?58	NT.A57	9.19	Yes	No	0	5	4
5	NT.?58	NT.L59	8.08	Yes	No	0	5	7
6	NT.?58	NT.Q82	16.83	Yes	Yes	1	5	6
7	Lig	NT.?58	17.72	Yes	Yes	1	0	5
8	NT.L59	NT.P60	4.93	No	No	0	7	5
9	NT.?62	NT.V63	4.44	Yes	No	0	4	4
10	NT.?62	NT.E87	11.86	Yes	No	0	4	5
11	NT.F69	NT.I64	5.02	No	Yes	0	8	7
12	NT.I64	NT.I89	11.77	Yes	No	0	7	8
13	NT.A68	NT.P65	5.61	No	No	0	8	6
14	NT.Q67	NT.R70	9.35	No	No	0	3	2
15	NT.D95	NT.Q67	10.44	Yes	No	0	6	3
16	NT.F69	NT.F94	9.65	No	Yes	0	8	9
17	NT.F69	NT.L97	6.09	No	No	0	8	8
18	NT.?71	NT.L72	4.83	No	No	0	5	7
19	NT.L100	NT.V75	5.96	No	No	0	9	7
20	NT.I76	NT.N99	5.66	No	No	0	3	5
21	NT.I78	NT.L100	8.56	No	No	0	8	9
22	NT.E79	NT.S81	8.62	No	No	0	5	6
23	NT.E79	NT.L104	5.3	No	No	0	5	5
24	NT.Q82	NT.S81	7.22	Yes	No	0	6	6
25	NT.Q106	NT.S81	4.33	No	No	0	7	6
26	NT.N107	NT.Q82	11.88	Yes	Yes	1	7	6
27	Lig	NT.Q82	13.56	Yes	Yes	1	0	6
28	NT.L86	NT.T108	4.42	No	No	0	8	8
29	NT.E87	NT.R88	13.96	No	No	0	5	1
30	NT.E87	NT.R112	19.77	No	No	0	5	5
31	NT.?113	NT.R88	14.18	Yes	No	0	1	1
32	NT.F94	NT.I89	5.02	Yes	No	0	9	8
33	NT.I114	NT.I89	4.42	Yes	No	0	8	8
34	NT.D95	NT.N92	12.12	Yes	No	6	6	6
35	NT.I120	NT.N92	7.08	Yes	No	6	5	6
36	NT.F119	NT.F94	11.79	No	Yes	0	8	9
37	NT.D95	NT.I120	5.6	Yes	Yes	6	6	5
38	NT.N121	NT.N96	10.9	No	No	0	7	5
39	NT.L98	NT.P123	6.57	No	No	0	6	4
40	NT.L98	NT.R124	7.29	No	No	0	6	6
41	NT.N99	NT.R124	8.44	No	No	0	5	6
42	Lig	NT.E102	18.78	Yes	No	0	0	7
43	NT.I103	NT.L125	7.14	No	No	0	8	9
44	NT.I103	NT.L128	5.71	No	No	0	8	8
45	NT.L104	NT.Q106	15.97	No	No	0	5	7
46	NT.I105	NT.I130	5.89	No	No	0	8	8
47	NT.N107	NT.Q106	18.49	Yes	No	0	7	7
48	NT.N107	NT.N132	5.45	Yes	No	1	7	8
49	Lig	NT.N107	12.04	Yes	Yes	1	0	7
50	NT.L111	NT.T108	7.37	No	No	0	7	8
51	NT.?109	NT.N110	8.19	No	No	0	6	5
52	NT.I114	NT.L111	5.71	Yes	No	0	8	7
53	NT.?113	NT.R112	4.73	Yes	No	0	1	5
54	NT.?113	NT.I114	5.55	Yes	Yes	0	1	8
55	NT.?113	NT.E115	16.75	Yes	No	0	1	5
56	NT.I114	NT.I135	5.89	Yes	Yes	0	8	7
57	NT.?117	NT.I120	4.98	No	Yes	0	3	5
58	NT.?117	NT.D140	4.73	No	Yes	0	3	3
59	NT.?143	NT.I120	8.51	Yes	Yes	6	4	5
60	NT.L122	NT.L125	6.92	No	No	0	8	9
61	NT.F151	NT.L125	6.09	Yes	No	0	5	9
62	NT.?126	NT.?127	12.85	No	Yes	0	5	6
63	NT.?126	NT.E148	6.32	No	No	0	5	5
64	NT.?126	NT.F151	10.17	No	Yes	0	5	5
65	NT.?127	NT.S129	10.22	Yes	No	1	6	7
66	NT.?127	NT.I152	5.55	Yes	No	1	6	4
67	NT.?127	NT.E154	14.18	Yes	Yes	1	6	7
68	Lig	NT.?127	26.77	Yes	Yes	1	0	6
69	NT.I130	NT.L128	7.14	No	No	0	8	8
70	NT.F151	NT.L128	6.09	Yes	No	0	5	8
71	NT.E154	NT.S129	10.06	Yes	No	1	7	7
72	NT.?131	NT.N132	5.88	Yes	No	1	7	8
73	NT.?131	NT.T133	7.89	Yes	Yes	1	7	8
74	NT.?131	NT.?156	30.16	Yes	Yes	1	7	7
75	NT.?131	NT.D157	5.81	Yes	No	1	7	6
76	NT.?131	NT.N158	5.88	Yes	Yes	1	7	9
77	Lig	NT.N132	16.38	Yes	No	1	0	8
78	NT.?134	NT.T133	7.71	No	Yes	0	5	8
79	NT.I135	NT.T133	7.6	Yes	Yes	0	7	8
80	NT.N158	NT.T133	8.77	Yes	Yes	1	9	8
81	NT.?134	NT.R136	8.48	No	No	0	5	3
82	NT.?134	NT.H160	6.73	No	No	0	5	3
83	NT.I135	NT.I161	4.42	Yes	No	0	7	7
84	NT.F138	NT.P139	8.67	No	No	0	5	9
85	NT.F138	NT.P165	7.22	No	No	0	5	7
86	NT.F138	NT.F169	5.36	No	No	0	5	6
87	NT.D140	NT.T142	7.23	Yes	No	6	3	4
88	NT.?143	NT.D140	7.29	Yes	Yes	6	4	3
89	NT.M172	NT.V141	9.13	No	No	0	6	5
90	NT.?143	NT.T142	5.28	Yes	No	6	4	4
91	NT.?143	NT.F145	16.71	Yes	No	0	4	3
92	NT.N173	NT.S146	4.47	Yes	No	0	4	7
93	NT.N174	NT.S147	5.96	No	No	0	4	5
94	Lig	NT.E148	9.02	Yes	No	1	0	5
95	Lig	NT.S149	16.53	Yes	No	0	0	3
96	Lig	NT.N150	13.22	Yes	No	0	0	5
97	NT.F151	NT.N173	9.67	Yes	Yes	0	5	4
98	NT.I152	NT.T178	4.56	No	No	0	4	6
99	Lig	NT.I152	11.1	Yes	No	1	0	4
100	NT.I155	NT.L153	8.56	No	No	0	8	9
101	NT.?180	NT.E154	8.7	Yes	Yes	1	5	7
102	Lig	NT.E154	9.63	Yes	Yes	1	0	7
103	NT.I155	NT.N184	5.66	No	Yes	0	8	9
104	NT.?156	NT.D157	17.44	Yes	No	1	7	6
105	NT.?156	NT.N158	14.7	Yes	Yes	1	7	9
106	NT.?156	NT.?182	15.86	Yes	Yes	1	7	6
107	NT.?156	NT.N184	14.7	Yes	Yes	1	7	9
108	Lig	NT.D157	16.88	Yes	No	1	0	6
109	NT.I161	NT.N158	5.66	No	Yes	0	7	9
110	NT.N158	NT.N184	6.81	Yes	Yes	1	9	9
111	Lig	NT.H160	7.71	Yes	No	1	0	3
112	NT.F186	NT.I161	6.28	Yes	No	0	8	7
113	NT.T162	NT.T163	9.42	No	No	0	3	3
114	NT.F186	NT.I164	15.07	Yes	No	0	8	7
115	NT.I164	NT.V189	4.61	No	No	0	7	7
116	NT.?166	NT.P165	5.73	Yes	No	0	4	7
117	NT.A168	NT.P165	5.61	No	No	0	7	7
118	NT.?166	NT.N167	9.58	Yes	No	0	4	7
119	NT.?166	NT.Q190	6.96	Yes	No	0	4	2
120	NT.N167	NT.N195	13.62	No	Yes	0	7	5
121	NT.F169	NT.L179	10.96	No	No	0	6	8
122	NT.F169	NT.F194	9.65	No	Yes	0	6	9
123	NT.?171	NT.Q170	6.96	No	No	0	4	3
124	NT.N195	NT.Q170	13.2	Yes	No	9	5	3
125	NT.?196	NT.Q170	8.13	No	No	9	6	3
126	NT.E175	NT.N173	5.26	No	Yes	0	5	4
127	NT.E175	NT.S176	5.75	No	No	0	5	5
128	NT.S176	NT.T198	6.4	No	No	0	5	5
129	NT.T197	NT.V177	6.35	No	No	0	5	3
130	NT.L179	NT.L199	6.92	No	No	0	8	8
131	NT.?180	NT.L181	6.61	Yes	No	0	5	8
132	NT.?180	NT.?182	16.87	Yes	Yes	1	5	6
133	Lig	NT.?180	4.82	Yes	Yes	1	0	5
134	NT.?182	NT.?183	15.26	Yes	Yes	1	6	7
135	NT.?182	NT.N184	10.68	Yes	Yes	1	6	9
136	NT.?182	NT.E203	16.75	Yes	No	0	6	5
137	NT.?182	NT.?205	8.03	Yes	No	0	6	7
138	Lig	NT.?182	13.89	Yes	Yes	1	0	6
139	NT.?183	NT.N184	8.38	Yes	Yes	1	7	9
140	NT.?183	NT.N207	5.99	Yes	No	1	7	9
141	Lig	NT.?183	5.3	Yes	Yes	1	0	7
142	NT.F186	NT.N184	15.71	Yes	Yes	1	8	9
143	NT.N184	NT.N207	5.45	Yes	No	1	9	9
144	NT.?185	NT.H209	10.09	No	Yes	0	4	1
145	NT.F186	NT.N207	10.87	Yes	No	1	8	9
146	NT.E187	NT.H209	7.39	No	Yes	0	2	1
147	NT.M213	NT.V189	4.56	No	No	0	6	7
148	NT.H214	NT.S191	6.97	No	No	0	5	5
149	NT.H192	NT.R219	9.03	No	No	0	5	1
150	NT.?220	NT.H192	4.48	No	No	0	5	5
151	NT.F194	NT.L199	4.87	Yes	No	0	9	8
152	NT.F194	NT.L202	6.09	Yes	No	0	9	7
153	NT.F194	NT.F218	13.93	Yes	Yes	0	9	8
154	NT.?196	NT.N195	8.38	No	Yes	9	6	5
155	NT.?220	NT.N195	10.78	No	Yes	0	5	5
156	NT.?196	NT.T197	6.43	No	No	0	6	5
157	NT.L199	NT.P224	6.57	No	Yes	0	8	8
158	NT.E203	NT.S201	4.31	No	No	0	5	5
159	NT.S201	NT.T226	6.4	No	No	0	5	4
160	NT.L202	NT.L204	11.07	No	No	0	7	9
161	NT.L202	NT.P224	4.93	No	Yes	0	7	8
162	NT.L204	NT.L210	5.54	No	No	0	9	8
163	NT.?205	NT.E206	9.49	No	No	0	7	4
164	NT.?205	NT.D228	8.1	No	No	0	7	9
165	Lig	NT.E206	16.56	Yes	No	1	0	4
166	NT.H209	NT.V208	6.92	Yes	No	0	1	1
167	NT.L210	NT.T232	4.42	No	No	0	8	9
168	NT.M213	NT.P238	11.74	No	No	0	6	9
169	NT.?216	NT.H214	7.85	No	No	0	3	5
170	NT.F218	NT.P224	14.45	Yes	Yes	0	8	8
171	NT.F218	NT.P238	7.22	Yes	No	0	8	9
172	NT.?240	NT.F218	4.74	Yes	Yes	0	2	8
173	NT.?240	NT.R219	23.63	Yes	No	0	2	1
174	NT.?223	NT.P224	10.02	No	Yes	0	7	8
175	NT.?223	NT.S244	10.48	No	No	0	7	4
176	NT.?225	NT.T226	5.28	No	No	0	3	4
177	NT.?225	NT.Q246	6.35	No	No	0	3	6
178	NT.R247	NT.T226	5.17	No	No	0	5	4
179	NT.I245	NT.L227	5.71	No	No	0	8	8
180	NT.D228	NT.S230	7.36	No	No	0	9	9
181	NT.D228	NT.I249	13.99	No	No	0	9	5
182	NT.I229	NT.L237	5.71	Yes	No	0	7	7
183	NT.S230	NT.T251	7.99	No	No	0	9	4
184	NT.?233	NT.T232	4.4	No	No	0	3	9
185	NT.?233	NT.S255	8.96	No	No	0	3	4
186	NT.L237	NT.L242	5.54	No	No	0	7	9
187	NT.L237	NT.P260	8.21	No	Yes	0	7	6
188	NT.?240	NT.S239	5.84	Yes	No	0	2	4
189	NT.?240	NT.?241	23.48	Yes	Yes	10	2	7
190	NT.?240	NT.E243	14.18	Yes	No	10	2	3
191	NT.?241	NT.L242	4.83	Yes	No	0	7	9
192	NT.?241	NT.E243	19.64	Yes	No	10	7	3
193	NT.?241	NT.S244	6.55	Yes	No	0	7	4
194	NT.E270	NT.R247	5.82	No	No	0	6	5
195	Lig	NT.R247	7.21	Yes	No	1	0	5
196	NT.F265	NT.L248	6.09	Yes	No	0	7	9
197	NT.?254	NT.S252	5.84	Yes	No	0	2	7
198	NT.?254	NT.S255	4.38	Yes	No	0	2	4
199	NT.?254	NT.?257	5.62	Yes	No	12	2	7
200	NT.?254	NT.T274	5.73	Yes	No	0	2	9
201	NT.?254	NT.?275	24.88	Yes	Yes	12	2	8
202	NT.?257	NT.?258	6.9	No	No	0	7	5
203	NT.?257	NT.?275	4.82	No	Yes	12	7	8
204	NT.L259	NT.P260	4.93	No	Yes	0	6	6
205	NT.H278	NT.L259	9	No	No	0	9	6
206	NT.F265	NT.P260	7.22	Yes	Yes	0	7	6
207	NT.E263	NT.S261	8.62	No	No	0	4	4
208	NT.F282	NT.R262	11.76	Yes	No	0	8	5
209	NT.F265	NT.L268	9.74	Yes	No	11	7	6
210	NT.F265	NT.F282	7.5	Yes	Yes	11	7	8
211	NT.F282	NT.L268	7.31	Yes	No	11	8	6
212	NT.E270	NT.R342	11.63	No	No	0	6	4
213	NT.A271	NT.L273	4.73	No	No	0	7	7
214	NT.?275	NT.P276	14.37	Yes	No	0	8	7
215	NT.?275	NT.H278	18.76	Yes	No	0	8	9
216	E1.I431	NT.?275	18.05	No	Yes	0	8	8
217	NT.P276	NT.P347	5.84	No	No	0	7	8
218	NT.?279	NT.?280	25.4	No	No	0	9	9
219	NT.?279	NT.F282	7.83	No	Yes	0	9	8
220	NT.?279	NT.?343	15.87	No	No	0	9	9
221	NT.?280	NT.R283	10.41	No	No	0	9	3
222	NT.?280	NT.?353	9.52	No	No	0	9	9
223	E1.?427	NT.A281	6.13	Yes	No	0	7	8
224	NT.E346	NT.R283	10.47	No	No	0	4	3
225	NT.?331	NT.D330	6.6	No	No	1	1	4
226	Lig	NT.D330	25.24	Yes	No	1	0	4
227	NT.?331	NT.E332	7.73	No	No	1	1	4
228	NT.?331	NT.?333	6.55	No	Yes	1	1	1
229	NT.?333	NT.E332	6.44	Yes	No	1	1	4
230	NT.?333	NT.?334	18.78	Yes	No	1	1	3
231	NT.?333	NT.?336	21.62	Yes	Yes	1	1	6
232	NT.?334	NT.?336	6.46	No	Yes	1	3	6
233	NT.?336	NT.F335	9.13	Yes	No	0	6	1
234	NT.?336	NT.L337	4.45	Yes	No	0	6	3
235	NT.?336	NT.P338	5.28	Yes	No	0	6	3
236	NT.?339	NT.T340	6.16	No	No	0	3	4
237	NT.?343	NT.R342	7.81	No	No	0	9	4
238	NT.E346	NT.P347	7.86	No	No	0	4	8
239	E2.?510	NT.F350	6.54	No	No	0	6	8
240	E1.Q434	NT.N351	6.6	No	No	0	9	8
241	NT.?353	NT.E354	8.51	No	Yes	0	9	7
242	E2.S512	NT.E354	4.31	No	Yes	0	9	7
243	7x31	NT.E354	12.7	No	Yes	0	7	7
244	7x34	NT.E354	8.7	No	Yes	0	9	7
245	1x36	NT.D355	9.53	Yes	Yes	2	9	7
246	2x64	NT.D355	6.65	Yes	Yes	2	9	7
247	E1.?423	NT.D355	8.1	No	Yes	2	5	7
248	E1.?424	NT.D355	7.1	No	Yes	2	7	7
249	2x64	NT.I356	5.6	Yes	No	0	9	8
250	E2.S512	NT.I356	4.64	No	No	0	9	8
251	1x36	NT.M357	4.96	Yes	No	2	9	7
252	1x39	NT.M357	5.83	Yes	No	0	9	7
253	2x64	NT.M357	9.7	Yes	No	2	9	7
254	1x32	NT.?358	30.52	Yes	No	0	6	8
255	1x32	1x33	5.28	Yes	No	2	6	4
256	1x32	1x34	11.85	Yes	No	0	6	5
257	1x32	1x36	7.09	Yes	Yes	2	6	9
258	1x33	1x36	8.34	No	Yes	2	4	9
259	1x34	1x35	9.74	No	No	0	5	8
260	1x36	2x64	17.87	Yes	Yes	2	9	9
261	1x38	7x38	4.47	No	No	0	6	9
262	1x39	2x57	5.71	Yes	No	0	9	8
263	1x39	2x61	4.87	Yes	No	0	9	9
264	1x39	7x38	6.14	Yes	No	0	9	9
265	1x40	2x61	9.08	No	No	0	9	9
266	1x42	7x42	6.77	No	No	0	8	9
267	1x43	2x57	5.49	No	No	0	6	8
268	1x44	1x48	4.37	No	No	0	4	2
269	1x45	7x47	4.45	No	Yes	0	5	9
270	1x47	2x54	4.98	No	No	0	5	9
271	1x49	1x50	4.79	Yes	Yes	3	7	9
272	1x49	1x52	6.43	Yes	No	0	7	4
273	1x49	7x50	4.3	Yes	No	3	7	9
274	1x50	2x47	8.94	Yes	No	0	9	8
275	1x50	2x50	9.42	Yes	Yes	3	9	9
276	1x50	7x50	11.4	Yes	No	3	9	9
277	1x53	2x47	8.08	No	No	0	9	8
278	1x54	2x44	7.41	No	No	0	5	8
279	1x54	2x47	4.5	No	No	0	5	8
280	1x55	1x59	6.49	No	No	0	1	5
281	1x56	8x50	10.49	No	Yes	0	7	8
282	1x56	8x57	4.47	No	No	0	7	7
283	1x57	2x44	4.45	No	No	0	6	8
284	1x57	8x50	4.87	No	Yes	0	6	8
285	1x59	8x57	5.9	No	No	0	5	7
286	1x60	I1.?389	5.84	No	Yes	7	7	3
287	1x60	8x53	10.31	No	Yes	7	7	8
288	I1.?389	I1.R388	18.9	Yes	No	0	3	5
289	I1.?389	I1.?390	15.26	Yes	No	0	3	4
290	8x52	I1.?389	34.26	No	Yes	7	6	3
291	8x53	I1.?389	9.24	Yes	Yes	7	8	3
292	2x37	2x39	6.99	No	No	0	8	6
293	2x37	2x40	9.06	No	No	0	8	7
294	2x40	8x53	8.34	No	Yes	0	7	8
295	2x41	2x45	7.25	No	Yes	8	7	7
296	2x41	4x43	6.28	No	No	0	7	3
297	2x41	4x46	4.98	No	Yes	8	7	7
298	2x42	3x45	4.47	No	No	0	7	4
299	2x42	3x46	5.71	No	No	0	7	9
300	2x43	7x53	13.75	No	Yes	0	7	9
301	2x43	7x54	4.83	No	No	0	7	7
302	2x44	2x45	5.88	No	Yes	0	8	7
303	2x45	4x46	16.83	Yes	Yes	8	7	7
304	2x45	4x50	5.65	Yes	Yes	8	7	5
305	2x46	2x50	6.79	Yes	Yes	3	8	9
306	2x46	3x42	7.37	Yes	No	0	8	8
307	2x46	3x43	5.54	Yes	No	3	8	9
308	2x46	7x49	8.24	Yes	Yes	3	8	9
309	2x46	7x53	5.38	Yes	Yes	3	8	9
310	2x48	4x50	8.02	No	Yes	0	5	5
311	2x49	3x38	4.73	No	No	0	8	7
312	2x50	3x39	7.36	Yes	No	0	9	8
313	2x50	7x46	8.83	Yes	No	0	9	9
314	2x50	7x49	8.08	Yes	Yes	3	9	9
315	2x51	2x55	10.96	No	No	0	4	4
316	2x52	2x54	10.34	Yes	No	14	7	9
317	2x52	2x55	8.89	Yes	No	0	7	4
318	2x52	2x56	5.77	Yes	Yes	14	7	7
319	2x53	3x35	4.83	No	No	0	8	8
320	2x53	7x41	8.25	No	Yes	0	8	7
321	2x53	7x46	9.2	No	No	0	8	9
322	2x54	2x56	9.39	No	Yes	14	9	7
323	2x56	2x57	9.42	Yes	No	0	7	8
324	2x56	2x60	18.05	Yes	No	0	7	8
325	2x56	3x32	10.04	Yes	No	0	7	8
326	2x56	E2x51	4.74	Yes	Yes	0	7	9
327	2x56	7x37	6.73	Yes	No	0	7	8
328	2x63	E1.W433	13.48	No	Yes	0	7	9
329	2x67	E1.H429	9.58	No	No	0	9	6
330	E1.?423	E1.?424	9.36	No	No	2	5	7
331	E1.?424	E1.Q425	5.8	No	No	0	7	4
332	E1.N428	E1.Q425	7.92	No	No	0	6	4
333	E1.H429	E1.Q425	9.89	No	No	0	6	4
334	E1.?426	E1.?427	28.81	Yes	Yes	13	9	7
335	E1.?426	E1.H429	6.25	Yes	No	0	9	6
336	E1.?426	E1.A430	13.79	Yes	No	13	9	9
337	E1.?426	E1.Q434	7.77	Yes	No	0	9	9
338	E1.?426	E2.S512	4.38	Yes	No	0	9	9
339	E1.?427	E1.N428	16.03	Yes	No	0	7	6
340	E1.?427	E1.A430	6.13	Yes	No	13	7	9
341	E1.I431	E1.T435	7.6	No	No	0	8	6
342	3x24	E1.W433	9.93	Yes	Yes	4	8	9
343	3x25	E1.W433	29.27	Yes	Yes	4	9	9
344	E1.W433	E2x50	4.88	Yes	Yes	4	9	9
345	3x22	3x24	6.32	No	Yes	4	9	8
346	3x22	3x25	6.46	No	Yes	4	9	9
347	3x24	3x25	19.39	Yes	Yes	4	8	9
348	3x24	3x27	10.28	Yes	No	0	8	3
349	3x25	E2.?508	4.32	Yes	Yes	4	9	8
350	3x25	E2x50	20.63	Yes	Yes	4	9	9
351	3x26	4x61	4.5	No	No	0	4	7
352	3x26	E2.?508	7.3	No	Yes	0	4	8
353	3x29	3x32	9	No	No	0	9	8
354	3x29	E2.?508	22.31	No	Yes	4	9	8
355	3x29	E2x50	7.76	No	Yes	4	9	9
356	3x30	4x57	8.32	No	No	0	8	9
357	3x33	E2.?508	5.8	No	Yes	0	8	8
358	3x34	4x50	6.01	No	Yes	0	8	5
359	3x36	3x37	5.75	No	No	0	8	9
360	3x36	7x41	4.38	No	Yes	0	8	7
361	3x37	5x47	11.83	No	No	0	9	9
362	3x38	4x50	11.39	No	Yes	0	7	5
363	3x38	4x53	4.5	No	No	0	7	7
364	3x40	5x47	7.39	No	No	0	7	9
365	3x41	3x42	4.3	Yes	No	0	8	8
366	3x41	3x44	12.9	Yes	No	0	8	8
367	3x41	3x45	13.04	Yes	No	0	8	4
368	3x41	4x49	10.57	Yes	No	0	8	8
369	3x42	4x46	6.02	No	Yes	0	8	7
370	3x43	7x49	9.61	No	Yes	3	9	9
371	3x43	7x53	5.38	No	Yes	3	9	9
372	3x44	5x53	4.56	No	No	0	8	4
373	3x46	3x50	5.01	No	No	0	9	8
374	3x47	5x54	9.12	No	No	0	8	8
375	3x47	5x58	17.2	No	Yes	0	8	9
376	3x49	3x53	8.47	No	No	0	9	8
377	3x50	5x58	9.45	No	Yes	0	8	9
378	3x50	7x53	8.27	No	Yes	0	8	9
379	3x51	3x55	16.98	No	No	0	5	5
380	3x51	5x57	7.32	No	Yes	0	5	6
381	3x52	3x56	11.25	No	Yes	0	5	3
382	3x55	3x56	12.9	No	Yes	0	5	3
383	I2.H473	I2.I472	5.3	No	No	0	4	5
384	I2.D475	I2.Q476	11.75	No	No	0	4	5
385	4x38	4x40	10.66	No	No	0	5	3
386	4x38	4x41	5.64	No	No	0	5	5
387	4x46	4x50	4.65	Yes	Yes	8	7	5
388	4x48	4x49	13.68	No	No	0	3	8
389	4x49	4x53	6.55	No	No	0	8	7
390	4x52	4x56	6.28	No	No	0	5	5
391	4x56	5x39	5.55	No	Yes	0	5	7
392	4x59	5x39	8.08	No	Yes	0	5	7
393	4x60	E2.?508	19.17	No	Yes	0	9	8
394	4x60	5x39	12.78	No	Yes	0	9	7
395	E2.D518	E2.S506	4.42	No	No	0	7	8
396	E2.M509	E2.N507	8.41	No	No	0	6	7
397	E2.D518	E2.N507	5.39	No	No	0	7	7
398	E2.?508	E2.M509	6.87	Yes	No	0	8	6
399	E2.?508	E2x50	18.74	Yes	Yes	4	8	9
400	E2.?508	E2x52	7.99	Yes	No	0	8	9
401	E2.V511	E2x50	4.79	No	Yes	0	9	9
402	E2.M517	E2.V511	9.13	No	No	0	8	9
403	E2.I513	E2x51	7.54	No	Yes	0	9	9
404	7x37	E2.I513	5.71	No	No	0	8	9
405	E2x50	E2x51	5.22	Yes	Yes	0	9	9
406	E2x51	E2x52	4.33	Yes	No	0	9	9
407	E2.M517	E2x51	6.22	No	Yes	0	8	9
408	7x41	E2x51	11.85	Yes	Yes	0	7	9
409	5x36	E2.D518	4.42	No	No	0	7	7
410	5x37	E2.V519	4.3	No	No	0	6	6
411	5x33	5x36	4.8	No	No	0	5	7
412	5x37	5x41	5.32	No	No	0	6	6
413	5x39	5x40	12.49	Yes	No	0	7	6
414	5x39	5x42	11.47	Yes	No	0	7	4
415	5x39	5x43	6.94	Yes	No	0	7	6
416	5x41	6x60	4.87	No	No	0	6	6
417	5x44	6x55	4.73	Yes	No	0	9	9
418	5x48	6x48	4.56	No	No	0	7	7
419	5x51	6x44	9.55	No	No	0	8	8
420	5x51	6x45	9.65	No	No	0	8	8
421	5x54	5x55	4.59	No	Yes	0	8	7
422	5x54	6x44	5.6	No	No	0	8	8
423	5x55	5x57	12.7	Yes	Yes	5	7	6
424	5x55	5x58	7.21	Yes	Yes	5	7	9
425	5x55	5x59	10.7	Yes	No	0	7	5
426	5x55	6x41	6.11	Yes	No	0	7	9
427	5x57	5x58	25.95	Yes	Yes	5	6	9
428	5x57	5x60	5.31	Yes	No	0	6	4
429	5x57	5x61	6.11	Yes	Yes	5	6	9
430	5x58	5x61	11.11	Yes	Yes	5	9	9
431	5x58	5x62	5.24	Yes	Yes	5	9	9
432	5x58	6x37	16.5	Yes	No	0	9	8
433	5x58	6x40	6.73	Yes	No	0	9	9
434	5x60	5x62	4.82	No	Yes	0	4	9
435	5x61	5x62	5.55	Yes	Yes	5	9	9
436	5x62	5x63	8.29	Yes	No	0	9	4
437	5x62	5x66	5.91	Yes	No	0	9	5
438	6x30	I3.N555	10.77	Yes	No	0	8	7
439	6x27	I3.M559	9.03	No	No	0	4	2
440	6x30	I3.M559	6.93	Yes	No	0	8	2
441	6x28	6x29	9.01	No	No	0	4	5
442	6x29	6x32	6.4	No	No	0	5	5
443	6x35	6x36	7.88	No	No	0	7	9
444	6x36	6x39	5.96	No	No	0	9	5
445	6x42	6x46	5.19	No	No	0	8	6
446	6x43	7x52	4.42	No	No	0	9	9
447	6x44	7x45	8.08	No	No	0	8	9
448	6x45	6x49	8.32	No	No	0	8	8
449	6x47	6x50	5.28	Yes	No	0	9	9
450	6x47	6x51	4.59	Yes	No	15	9	9
451	6x47	7x41	4.32	Yes	Yes	15	9	7
452	6x47	7x43	6.11	Yes	No	0	9	8
453	6x47	7x45	13.23	Yes	No	0	9	9
454	6x48	6x52	6.13	No	No	0	7	9
455	6x50	7x40	10.11	No	No	0	9	8
456	6x51	7x41	6.94	No	Yes	15	9	7
457	6x52	6x56	4.64	No	No	0	9	7
458	6x54	7x36	13.4	No	No	0	8	8
459	6x57	E3.L598	6.01	No	No	0	8	7
460	7x29	7x32	7.31	No	No	0	8	6
461	7x35	7x39	4.47	No	No	0	7	7
462	7x37	7x38	4.47	No	No	0	8	9
463	7x39	7x40	6.09	No	No	0	7	8
464	7x41	7x42	15.97	Yes	No	0	7	9
465	7x45	7x49	5.45	No	Yes	0	9	9
466	7x47	7x50	14.07	Yes	No	0	9	9
467	7x47	7x51	6.52	Yes	No	0	9	8
468	7x52	7x53	5.38	No	Yes	0	9	9
469	7x55	8x50	6.28	No	Yes	0	7	8
470	8x48	8x49	4.4	No	No	0	7	6
471	8x52	8x53	10.72	No	Yes	7	6	8
472	8x54	8x58	9.74	No	No	0	5	4
473	8x58	CT.?643	10.38	No	No	0	4	2
474	8x60	8x61	5.09	No	No	0	4	2
475	CT.?642	CT.?643	18.1	No	No	17	4	2
476	CT.?642	CT.?644	7.76	No	No	17	4	4
477	CT.?643	CT.?644	25.4	No	No	17	2	4
478	Lig	Lig	2525.4	Yes	Yes	1	0	0
479	6x53	6x54	4.29	No	No	0	7	8
480	NT.E90	NT.V63	4.28	No	No	0	6	4
481	NT.I83	NT.L86	4.28	No	No	0	7	8
482	NT.I103	NT.L100	4.28	No	No	0	8	9
483	NT.I229	NT.L227	4.28	Yes	No	0	7	8
484	NT.I229	NT.L256	4.28	Yes	No	0	7	8
485	NT.I245	NT.L242	4.28	No	No	0	8	9
486	NT.I245	NT.L248	4.28	No	No	0	8	9
487	1x47	2x58	4.28	No	No	0	5	6
488	4x39	4x43	4.28	No	No	0	3	3
489	6x39	7x52	4.28	No	No	0	5	9
490	NT.?137	NT.I135	4.26	No	Yes	0	3	7
491	NT.?171	NT.F145	4.25	No	No	0	4	3
492	NT.?185	NT.F186	4.25	No	Yes	0	4	8
493	Lig	NT.?328	4.25	Yes	No	1	0	1
494	NT.?71	NT.R70	4.24	No	No	0	5	2
495	Lig	NT.?77	4.24	Yes	No	0	0	5
496	NT.L153	NT.M172	4.24	No	No	0	9	6
497	NT.L234	NT.M213	4.24	No	No	0	7	6
498	NT.?216	NT.R219	4.24	No	No	0	3	1
499	NT.?275	NT.I277	4.16	Yes	No	0	8	8
500	3x41	4x45	4.16	Yes	No	0	8	5
501	5x62	6x33	4.16	Yes	No	0	9	7
502	4x47	4x51	4.15	No	No	16	1	1
503	NT.N73	NT.N99	4.09	No	No	0	4	5
504	NT.D95	NT.N121	4.04	Yes	No	0	6	7
505	8x56	I1.?389	4.04	No	Yes	0	3	3
506	E2.?508	E2.?510	4.02	Yes	No	0	8	6
507	NT.L269	NT.Q246	3.99	No	No	0	4	6
508	NT.?212	NT.E188	3.95	No	No	0	2	5
509	NT.?212	NT.E211	3.95	No	No	0	2	2
510	3x22	3x23	3.93	No	No	0	9	2
511	5x48	5x52	3.93	No	No	0	7	4
512	6x61	E3.P597	3.92	No	No	0	6	5
513	NT.P276	NT.P345	3.9	No	No	0	7	9
514	4x63	E2.V505	3.9	No	No	0	6	5
515	NT.?223	NT.T222	3.86	No	No	0	7	3
516	6x56	6x60	3.77	No	No	0	7	6
517	NT.F282	NT.L273	3.65	Yes	No	0	8	7
518	3x30	4x61	3.65	No	No	0	8	7
519	1x57	2x40	3.64	No	No	0	6	7
520	Lig	NT.?109	3.62	Yes	No	1	0	6
521	NT.?143	NT.V144	3.55	Yes	No	0	4	7
522	6x61	E3.V596	3.55	No	No	0	6	5
523	7x30	NT.P352	3.53	No	No	0	8	9
524	2x38	2x39	3.53	No	No	0	8	6
525	6x32	6x35	3.45	No	No	0	5	7
526	NT.I64	NT.P65	3.39	Yes	No	0	7	6
527	NT.A217	NT.V189	3.39	No	No	0	7	7
528	2x38	4x42	3.39	No	No	0	8	7
529	NT.?343	NT.A344	3.37	No	No	0	9	6
530	5x55	5x56	3.37	Yes	No	0	7	3
531	7x47	7x48	3.37	Yes	No	0	9	7
532	NT.?212	NT.L210	3.3	No	No	0	2	8
533	NT.?339	NT.L285	3.3	No	No	0	3	4
534	NT.L122	NT.P123	3.28	No	No	0	8	4
535	NT.L285	NT.P286	3.28	No	No	0	4	4
536	NT.L285	NT.P341	3.28	No	No	0	4	6
537	NT.S231	NT.S252	3.26	No	No	0	6	7
538	NT.A250	NT.I229	3.25	No	Yes	0	8	7
539	NT.D140	NT.P116	3.22	Yes	No	0	3	4
540	5x51	5x52	3.22	No	No	0	8	4
541	8x50	8x54	3.22	Yes	No	0	8	5
542	8x54	8x55	3.22	No	No	0	5	4
543	NT.S176	NT.T200	3.2	No	No	0	5	4
544	NT.S261	NT.T264	3.2	No	No	0	4	4
545	8x48	8x51	3.18	No	No	0	7	6
546	6x46	6x47	3.16	No	Yes	0	6	9
547	5x41	6x59	3.15	No	No	0	6	7
548	NT.T251	NT.T272	3.14	No	No	0	4	6
549	7x29	7x31	3.14	No	No	0	8	7
550	8x47	8x49	3.14	No	No	0	9	6
551	7x33	E3.I599	3.1	No	No	0	6	8
552	2x56	3x28	3.06	Yes	No	0	7	8
553	3x56	I2.A471	3.06	Yes	No	0	3	6
554	NT.A91	NT.E115	3.02	No	No	0	5	5
555	NT.L256	NT.S253	3	No	No	0	8	7
556	2x58	2x62	3	No	No	0	6	4
557	NT.N92	NT.S66	2.98	No	No	0	6	4
558	NT.N215	NT.S239	2.98	No	No	0	1	4
559	NT.?328	NT.W329	2.98	No	No	0	1	3
560	2x38	I2.L478	2.98	No	Yes	0	8	4
561	4x59	E2.V505	2.98	No	No	0	5	5
562	5x35	E2.V505	2.98	No	No	0	4	5
563	NT.N267	NT.V266	2.96	No	No	0	4	4
564	3x48	5x57	2.96	No	Yes	0	5	6
565	5x42	5x46	2.95	No	No	0	4	5
566	NT.I64	NT.I80	2.94	Yes	No	0	7	8
567	NT.I78	NT.I80	2.94	No	No	0	8	8
568	NT.I105	NT.I80	2.94	No	No	0	8	8
569	NT.?339	NT.P338	2.94	No	No	0	3	3
570	3x54	5x61	2.94	No	Yes	5	7	9
571	5x38	5x39	2.9	No	Yes	0	4	7
572	8x60	CT.?642	2.88	No	No	0	4	4
573	7x53	8x47	2.87	Yes	No	0	9	9
574	4x55	4x56	2.85	No	No	0	3	5
575	5x40	5x44	2.85	No	Yes	0	6	9
576	5x43	5x44	2.85	No	Yes	0	6	9
577	5x44	6x56	2.85	Yes	No	0	9	7
578	7x36	E3.I599	2.85	No	No	0	8	8
579	2x66	2x67	2.83	No	No	0	3	9
580	7x32	E3.I599	2.83	No	No	0	6	8
581	5x33	E2.E520	2.82	No	No	0	5	5
582	NT.A93	NT.F94	2.77	No	Yes	0	8	9
583	NT.A118	NT.F119	2.77	No	No	0	7	8
584	1x54	1x58	2.77	No	No	0	5	6
585	NT.?166	NT.A193	2.75	Yes	No	0	4	8
586	NT.?220	NT.A221	2.75	No	No	0	5	8
587	NT.?62	NT.S85	2.69	Yes	No	0	4	5
588	2x56	2x59	2.69	Yes	No	0	7	4
589	NT.?62	NT.V61	2.67	Yes	No	0	4	6
590	6x61	E2.V519	2.67	No	No	0	6	6
591	3x49	I2.L478	2.65	No	Yes	0	9	4
592	NT.R124	NT.S101	2.64	No	No	0	6	5
593	3x34	4x54	2.64	No	No	0	8	3
594	6x31	6x32	2.64	No	No	0	6	5
595	2x52	3x31	2.61	Yes	No	0	7	7
596	4x62	4x63	2.6	No	No	0	4	6
597	3x56	I2.Q476	2.59	Yes	No	0	3	5
598	NT.H209	NT.L159	2.57	Yes	No	0	1	3
599	4x41	I2.L478	2.57	No	Yes	0	5	4
600	I1.?390	I1.L391	2.48	No	No	0	4	5
601	1x48	1x49	2.47	No	Yes	0	2	7
602	I2.H473	I2.Q476	2.47	No	No	0	4	5
603	6x29	6x30	2.43	No	Yes	0	5	8
604	4x47	4x48	2.41	No	No	16	1	3
605	4x48	4x51	2.41	No	No	16	3	1
606	NT.D348	NT.F350	2.39	No	No	0	9	8
607	Lig	NT.R53	2.26	Yes	No	0	0	2
608	5x60	5x64	1.88	No	No	0	4	5
609	6x34	6x35	1.88	No	No	0	8	7
610	8x59	8x60	1.79	No	No	0	5	4
611	NT.?353	NT.P352	1.76	No	No	0	9	9
612	NT.P260	NT.T264	1.75	Yes	No	0	6	4
613	3x40	5x50	1.7	No	No	0	7	9
614	1x46	7x47	1.69	No	Yes	0	9	9
615	I2.?477	I2.L478	1.65	No	Yes	0	5	4
616	I3.N555	I3.P556	1.63	No	No	0	7	6
617	NT.A349	NT.D348	1.54	No	No	0	8	9
618	3x54	5x65	1.54	No	No	5	7	7
619	5x45	5x49	1.54	No	No	0	6	4
620	5x49	5x53	1.54	No	No	0	4	4
621	5x61	5x65	1.54	Yes	No	5	9	7
622	6x26	6x30	1.54	No	Yes	0	3	8
623	4x58	4x62	1.52	No	No	0	3	4
624	1x37	1x41	1.49	No	No	0	6	4
625	E3.L598	E3.V596	1.49	No	No	0	7	5
626	NT.D84	NT.S85	1.47	No	No	0	7	5
627	NT.Q235	NT.S255	1.44	No	No	0	4	4
628	NT.E243	NT.V266	1.43	No	No	0	3	4
629	4x44	4x45	1.43	No	No	0	2	5
630	NT.E74	NT.T52	1.41	No	No	0	4	3
631	NT.E187	NT.T163	1.41	No	No	0	2	3
632	NT.E188	NT.T163	1.41	No	No	0	5	3
633	1x38	1x41	1.38	No	No	0	6	4
634	I3.L558	I3.N555	1.37	No	No	0	4	7
635	NT.N173	NT.N174	1.36	Yes	No	0	4	4
636	I3.E557	I3.L558	1.33	No	No	0	4	4
637	1x40	2x65	1.24	No	No	0	9	5
638	1x51	2x51	1.24	No	No	0	3	4
639	NT.N284	NT.R262	1.21	No	No	0	5	5
640	NT.?258	NT.A236	0.94	No	No	0	5	5
641	I2.?477	I2.L474	0.83	No	No	0	5	3

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	NT.?58	12.955	4	1	5
2	NT.?62	5.415	4	0	4
3	NT.I64	5.78	4	0	7
4	NT.Q82	12.3725	4	1	6
5	NT.F94	7.3075	4	0	9
6	NT.D95	8.05	4	6	6
7	NT.N107	11.965	4	1	7
8	NT.?113	10.3025	4	0	1
9	NT.I114	5.3925	4	0	8
10	NT.I120	6.5425	4	6	5
11	NT.?127	13.914	5	1	6
12	NT.?131	11.124	5	1	7
13	NT.T133	7.9925	4	1	8
14	NT.I135	5.5425	4	0	7
15	NT.D140	5.6175	4	6	3
16	NT.?143	8.268	5	6	4
17	NT.F151	8.005	4	0	5
18	NT.E154	10.6425	4	1	7
19	NT.?156	18.572	5	1	7
20	NT.N158	8.364	5	1	9
21	NT.?166	6.255	4	0	4
22	NT.N173	5.19	4	0	4
23	NT.?180	9.25	4	1	5
24	NT.?182	13.9057	7	1	6
25	NT.?183	8.7325	4	1	7
26	NT.N184	9.62714	7	1	9
27	NT.F186	10.436	5	1	8
28	NT.F194	8.635	4	0	9
29	NT.N195	11.495	4	9	5
30	NT.H209	6.7425	4	0	1
31	NT.F218	10.085	4	0	8
32	NT.P224	8.9925	4	0	8
33	NT.I229	4.38	4	0	7
34	NT.?240	14.374	5	10	2
35	NT.?241	13.625	4	10	7
36	NT.?254	9.29	5	12	2
37	NT.P260	5.5275	4	0	6
38	NT.F265	7.6375	4	11	7
39	NT.?275	14.1733	6	12	8
40	NT.F282	7.61	5	11	8
41	NT.?333	13.3475	4	1	1
42	NT.?336	9.388	5	1	6
43	NT.E354	8.555	4	0	7
44	NT.D355	7.845	4	2	7
45	1x32	13.685	4	2	6
46	1x36	9.558	5	2	9
47	1x39	5.6375	4	0	9
48	1x49	4.4975	4	3	7
49	1x50	8.6375	4	3	9
50	I1.?389	14.59	6	7	3
51	2x45	8.9025	4	8	7
52	2x46	6.664	5	3	8
53	2x50	8.096	5	3	9
54	2x52	6.9025	4	14	7
55	2x56	7.76556	9	14	7
56	2x64	9.955	4	2	9
57	E1.?426	12.2	5	13	9
58	E1.?427	14.275	4	13	7
59	E1.W433	14.39	4	4	9
60	3x24	11.48	4	4	8
61	3x25	16.014	5	4	9
62	3x41	8.994	5	0	8
63	3x56	7.45	4	0	3
64	I2.L478	2.4625	4	0	4
65	4x46	8.12	4	8	7
66	4x50	7.144	5	8	5
67	E2.?508	10.7244	9	4	8
68	E2x50	10.3367	6	4	9
69	E2x51	6.65	6	0	9
70	5x39	8.60143	7	0	7
71	5x44	3.32	4	0	9
72	5x55	7.44667	6	5	7
73	5x57	10.0583	6	5	6
74	5x58	12.4237	8	5	9
75	5x61	5.45	5	5	9
76	5x62	5.66167	6	5	9
77	6x30	5.4175	4	0	8
78	6x47	6.115	6	15	9
79	7x41	8.61833	6	15	7
80	7x47	6.02	5	0	9
81	7x49	7.845	4	3	9
82	7x53	6.83833	6	3	9
83	8x50	6.215	4	0	8
84	8x53	9.6525	4	7	8
85	Lig	213.101	25	1	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	Lig	NT.?127	11.4306	26.77	Yes	Yes	1	0	6
2	NT.?126	NT.?127	10.7863	12.85	No	Yes	0	5	6
3	NT.?126	NT.F151	20.7651	10.17	No	Yes	0	5	5
4	Lig	NT.E148	11.0577	9.02	Yes	No	1	0	5
5	NT.?126	NT.E148	10.7035	6.32	No	No	0	5	5
6	NT.?113	NT.I114	14.2048	5.55	Yes	Yes	0	1	8
7	NT.I114	NT.I135	26.6458	5.89	Yes	Yes	0	8	7
8	NT.F186	NT.I164	11.7736	15.07	Yes	No	0	8	7
9	NT.I164	NT.V189	11.0858	4.61	No	No	0	7	7
10	NT.M213	NT.P238	10.3147	11.74	No	No	0	6	9
11	NT.F218	NT.P238	10.6052	7.22	Yes	No	0	8	9
12	NT.?240	NT.F218	14.834	4.74	Yes	Yes	0	2	8
13	NT.?240	NT.R219	19.0629	23.63	Yes	No	0	2	1
14	NT.H192	NT.R219	16.8657	9.03	No	No	0	5	1
15	NT.?220	NT.H192	16.316	4.48	No	No	0	5	5
16	NT.?220	NT.N195	15.2174	10.78	No	Yes	0	5	5
17	NT.N195	NT.Q170	11.4104	13.2	Yes	No	9	5	3
18	NT.?171	NT.Q170	10.8673	6.96	No	No	0	4	3
19	NT.?171	NT.F145	10.3018	4.25	No	No	0	4	3
20	NT.I135	NT.T133	25.7024	7.6	Yes	Yes	0	7	8
21	NT.?131	NT.T133	17.3556	7.89	Yes	Yes	1	7	8
22	Lig	NT.D157	10.1481	16.88	Yes	No	1	0	6
23	NT.F186	NT.N184	12.1538	15.71	Yes	Yes	1	8	9
24	Lig	NT.?183	12.9208	5.3	Yes	Yes	1	0	7
25	Lig	NT.R247	65.2413	7.21	Yes	No	1	0	5
26	NT.?240	NT.?241	24.2892	23.48	Yes	Yes	10	2	7
27	NT.I245	NT.L242	14.0983	4.28	No	No	0	8	9
28	NT.?241	NT.L242	28.396	4.83	Yes	No	0	7	9
29	NT.I245	NT.L248	14.4806	4.28	No	No	0	8	9
30	NT.F265	NT.L248	14.7322	6.09	Yes	No	0	7	9
31	NT.F265	NT.F282	32.5683	7.5	Yes	Yes	11	7	8
32	NT.?279	NT.F282	34.0701	7.83	No	Yes	0	9	8
33	NT.?279	NT.?343	66.2795	15.87	No	No	0	9	9
34	NT.?343	NT.R342	65.9937	7.81	No	No	0	9	4
35	NT.E270	NT.R342	65.854	11.63	No	No	0	6	4
36	NT.E270	NT.R247	65.7582	5.82	No	No	0	6	5
37	NT.L237	NT.L242	14.73	5.54	No	No	0	7	9
38	NT.L237	NT.P260	15.739	8.21	No	Yes	0	7	6
39	NT.F265	NT.P260	17.7029	7.22	Yes	Yes	0	7	6
40	NT.?279	NT.?280	94.6416	25.4	No	No	0	9	9
41	NT.?280	NT.?353	98.6329	9.52	No	No	0	9	9
42	E2.S512	NT.E354	98.6141	4.31	No	Yes	0	9	7
43	NT.?353	NT.E354	98.6393	8.51	No	Yes	0	9	7
44	3x29	E2.?508	13.027	22.31	No	Yes	4	9	8
45	3x29	3x32	13.2185	9	No	No	0	9	8
46	2x56	3x32	13.4989	10.04	Yes	No	0	7	8
47	2x56	2x57	98.5854	9.42	Yes	No	0	7	8
48	1x39	2x57	98.653	5.71	Yes	No	0	9	8
49	1x39	NT.M357	100	5.83	Yes	No	0	9	7
50	2x64	NT.M357	97.553	9.7	Yes	No	2	9	7
51	2x64	NT.I356	97.9025	5.6	Yes	No	0	9	8
52	E2.S512	NT.I356	97.9176	4.64	No	No	0	9	8
53	E2.?508	E2x50	16.5406	18.74	Yes	Yes	4	8	9
54	E2x50	E2x51	19.9408	5.22	Yes	Yes	0	9	9
55	2x56	E2x51	85.6141	4.74	Yes	Yes	0	7	9
56	E2.?508	E2x52	16.4539	7.99	Yes	No	0	8	9
57	E2x51	E2x52	16.7393	4.33	Yes	No	0	9	9
58	7x41	E2x51	65.1042	11.85	Yes	Yes	0	7	9
59	1x50	2x50	14.4867	9.42	Yes	Yes	3	9	9
60	2x50	7x46	27.5796	8.83	Yes	No	0	9	9
61	2x53	7x46	27.7891	9.2	No	No	0	8	9
62	2x53	7x41	28.2484	8.25	No	Yes	0	8	7
63	1x50	2x47	11.422	8.94	Yes	No	0	9	8
64	1x54	2x47	10.8647	4.5	No	No	0	5	8
65	1x54	2x44	10.3284	7.41	No	No	0	5	8
66	1x57	2x44	11.6401	4.45	No	No	0	6	8
67	2x46	3x42	15.1073	7.37	Yes	No	0	8	8
68	2x46	2x50	14.2037	6.79	Yes	Yes	3	8	9
69	2x46	7x49	14.689	8.24	Yes	Yes	3	8	9
70	7x45	7x49	23.0653	5.45	No	Yes	0	9	9
71	6x47	7x45	34.0668	13.23	Yes	No	0	9	9
72	6x47	7x41	35.3022	4.32	Yes	Yes	15	9	7
73	2x46	7x53	15.8866	5.38	Yes	Yes	3	8	9
74	5x54	6x44	10.9853	5.6	No	No	0	8	8
75	6x44	7x45	13.6004	8.08	No	No	0	8	9
76	4x60	5x39	31.3833	12.78	No	Yes	0	9	7
77	4x60	E2.?508	32.2098	19.17	No	Yes	0	9	8
78	5x41	6x60	12.8352	4.87	No	No	0	6	6
79	6x56	6x60	14.2577	3.77	No	No	0	7	6
80	5x44	6x56	16.3599	2.85	Yes	No	0	9	7
81	5x39	5x40	10.3151	12.49	Yes	No	0	7	6
82	5x39	5x43	10.3151	6.94	Yes	No	0	7	6
83	6x35	6x36	11.3888	7.88	No	No	0	7	9
84	6x36	6x39	12.197	5.96	No	No	0	9	5
85	6x39	7x52	13.0044	4.28	No	No	0	5	9
86	7x52	7x53	14.617	5.38	No	Yes	0	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
NT.?58	NT.A57	9.19	1	Yes	No	5	4	1	2
NT.?58	NT.L59	8.08	1	Yes	No	5	7	1	2
NT.?58	NT.Q82	16.83	1	Yes	Yes	5	6	1	1
Lig	NT.?58	17.72	1	Yes	Yes	0	5	0	1
NT.Q82	NT.S81	7.22	1	Yes	No	6	6	1	2
NT.Q106	NT.S81	4.33	0	No	No	7	6	2	2
NT.N107	NT.Q82	11.88	1	Yes	Yes	7	6	1	1
Lig	NT.Q82	13.56	1	Yes	Yes	0	6	0	1
Lig	NT.E102	18.78	1	Yes	No	0	7	0	1
NT.N107	NT.Q106	18.49	1	Yes	No	7	7	1	2
NT.N107	NT.N132	5.45	1	Yes	No	7	8	1	1
Lig	NT.N107	12.04	1	Yes	Yes	0	7	0	1
NT.?109	NT.N110	8.19	1	No	No	6	5	1	2
NT.?126	NT.?127	12.85	0	No	Yes	5	6	2	1
NT.?126	NT.E148	6.32	0	No	No	5	5	2	1
NT.?127	NT.S129	10.22	1	Yes	No	6	7	1	2
NT.?127	NT.I152	5.55	1	Yes	No	6	4	1	1
NT.?127	NT.E154	14.18	1	Yes	Yes	6	7	1	1
Lig	NT.?127	26.77	1	Yes	Yes	0	6	0	1
NT.E154	NT.S129	10.06	1	Yes	No	7	7	1	2
NT.?131	NT.N132	5.88	1	Yes	No	7	8	2	1
NT.?131	NT.?156	30.16	1	Yes	Yes	7	7	2	2
NT.?131	NT.D157	5.81	1	Yes	No	7	6	2	1
Lig	NT.N132	16.38	1	Yes	No	0	8	0	1
NT.?134	NT.H160	6.73	0	No	No	5	3	2	1
Lig	NT.E148	9.02	1	Yes	No	0	5	0	1
Lig	NT.S149	16.53	1	Yes	No	0	3	0	1
Lig	NT.N150	13.22	1	Yes	No	0	5	0	1
NT.I152	NT.T178	4.56	1	No	No	4	6	1	2
Lig	NT.I152	11.1	1	Yes	No	0	4	0	1
NT.?180	NT.E154	8.7	1	Yes	Yes	5	7	1	1
Lig	NT.E154	9.63	1	Yes	Yes	0	7	0	1
NT.?156	NT.D157	17.44	1	Yes	No	7	6	2	1
NT.?156	NT.?182	15.86	1	Yes	Yes	7	6	2	1
NT.?156	NT.N184	14.7	1	Yes	Yes	7	9	2	2
Lig	NT.D157	16.88	1	Yes	No	0	6	0	1
Lig	NT.H160	7.71	1	Yes	No	0	3	0	1
NT.?180	NT.L181	6.61	1	Yes	No	5	8	1	2
NT.?180	NT.?182	16.87	1	Yes	Yes	5	6	1	1
Lig	NT.?180	4.82	1	Yes	Yes	0	5	0	1
NT.?182	NT.?183	15.26	1	Yes	Yes	6	7	1	1
NT.?182	NT.N184	10.68	1	Yes	Yes	6	9	1	2
NT.?182	NT.E203	16.75	1	Yes	No	6	5	1	2
NT.?182	NT.?205	8.03	1	Yes	No	6	7	1	2
Lig	NT.?182	13.89	1	Yes	Yes	0	6	0	1
NT.?183	NT.N184	8.38	1	Yes	Yes	7	9	1	2
NT.?183	NT.N207	5.99	1	Yes	No	7	9	1	2
Lig	NT.?183	5.3	1	Yes	Yes	0	7	0	1
NT.N184	NT.N207	5.45	1	Yes	No	9	9	2	2
NT.?205	NT.E206	9.49	0	No	No	7	4	2	1
Lig	NT.E206	16.56	1	Yes	No	0	4	0	1
NT.R247	NT.T226	5.17	1	No	No	5	4	1	2
NT.E270	NT.R247	5.82	0	No	No	6	5	2	1
Lig	NT.R247	7.21	1	Yes	No	0	5	0	1
NT.?331	NT.D330	6.6	1	No	No	1	4	2	1
Lig	NT.D330	25.24	1	Yes	No	0	4	0	1
Lig	NT.?328	4.25	1	Yes	No	0	1	0	1
Lig	NT.?77	4.24	1	Yes	No	0	5	0	1
Lig	NT.?109	3.62	1	Yes	No	0	6	0	1
NT.?328	NT.W329	2.98	1	No	No	1	3	1	2
Lig	NT.R53	2.26	1	Yes	No	0	2	0	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
100.00	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
100.00	Single	6D35	Cholesterol	6D35-SMO-Cholesterol
100.00	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
100.00	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
100.00	Single	6UO8	SKF97541	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
100.00	Single	6UO9	SKF97541	6UO9-GABA_B1, GABA_B2-SKF97541
100.00	Single	6W2X	PubChem 5311042	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
100.00	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
100.00	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
100.00	Single	7C7Q	Baclofen	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
100.00	Single	7C7S	CGP54626	7C7S-GABA_B1, GABA_B2-CGP54626
100.00	Single	7CUM	CGP54626	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
100.00	Single	7DD5	Ca3	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
100.00	Single	7DGE	Quisqualate	7DGE-mGlu1; mGlu1-Quisqualate
100.00	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
100.00	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
100.00	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
100.00	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
100.00	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
100.00	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
100.00	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
100.00	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
100.00	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
100.00	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
100.00	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
100.00	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
100.00	Single	7EB2	Baclofen	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
100.00	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
100.00	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
100.00	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
100.00	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
100.00	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
100.00	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
100.00	Single	7FIH	hCG	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
100.00	Single	7FII	hCG	7FII-LH-hCG-6fuf
100.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
100.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
100.00	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
100.00	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
100.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
100.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
100.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
100.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
100.00	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
100.00	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
100.00	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
100.00	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
100.00	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
100.00	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
100.00	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
100.00	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
100.00	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
100.00	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
100.00	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
100.00	Single	7T9N	M22 Fab	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
100.00	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
100.00	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
100.00	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
100.00	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
100.00	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
100.00	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
100.00	Single	7XW6	M22 Fab	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
100.00	Single	7XW7	K1-70	7XW7-TSH-K1-70
100.00	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
100.00	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
100.00	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
100.00	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
100.00	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
100.00	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
100.00	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
100.00	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
100.00	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
100.00	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
100.00	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
100.00	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
100.00	Single	8JD0	Glutamate	8JD0-mGlu2; mGlu3-Glutamate-J9R
100.00	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
100.00	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
100.00	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
100.00	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
100.00	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
100.00	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
100.00	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
100.00	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
100.00	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
100.00	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
100.00	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
100.00	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
100.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
100.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
100.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
100.00	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
100.00	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
100.00	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
100.00	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
100.00	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
100.00	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
100.00	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
100.00	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
100.00	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
100.00	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
100.00	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
100.00	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
100.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
100.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
100.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
100.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
100.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
100.00	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
100.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
100.00	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
100.00	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
100.00	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
100.00	Consensus	class-c_off	Orthosteric Ligand	gabab_off mglu_off
100.00	Consensus	class-c_off	Orthosteric Ligand	gabab_off mglu_off
100.00	Consensus	class-c_on	Orthosteric Ligand	gabab_on mglu_on
100.00	Consensus	class-c_on	Orthosteric Ligand	gabab_on mglu_on
100.00	Consensus	fsh_on_allo	Orthosteric Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
100.00	Consensus	gabab_off	Orthosteric Ligand	7C7S-GABA_B1, GABA_B2-CGP54626 7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid 6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
100.00	Consensus	gabab_on	Orthosteric Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
100.00	Consensus	gi_class-c	Orthosteric Ligand	gi_mglu gi_gaba
100.00	Consensus	gi_class-c	Orthosteric Ligand	gi_mglu gi_gaba
100.00	Consensus	gi_gaba	Orthosteric Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
100.00	Consensus	gi_mglu	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
100.00	Consensus	gi_mglu	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
100.00	Consensus	gphr_on	Orthosteric Ligand	lh_on tsh_on
100.00	Consensus	gs_gphr	Orthosteric Ligand	7T9I-TSH-TSH-Gs/&β;1/&γ;2 7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
100.00	Consensus	gs_protein	Orthosteric Ligand	gs_gphr
100.00	Consensus	lh_on_allo	Orthosteric Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
100.00	Consensus	mglu2_off	Orthosteric Ligand	7MTQ-mGlu2; mGlu2-LY341495
100.00	Consensus	mglu2_off	Orthosteric Ligand	7MTQ-mGlu2; mGlu2-LY341495
100.00	Consensus	mglu2_on	Orthosteric Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
100.00	Consensus	mglu2_on	Orthosteric Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
100.00	Consensus	mglu3_off	Orthosteric Ligand	7WI8-mGlu3; mGlu3-LY341495 7WIH-mGlu3; mGlu3-LY2794193
100.00	Consensus	mglu3_off	Orthosteric Ligand	7WI8-mGlu3; mGlu3-LY341495 7WIH-mGlu3; mGlu3-LY2794193
100.00	Consensus	mglu4_on	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
100.00	Consensus	mglu4_on	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
100.00	Consensus	mglu5_off	Orthosteric Ligand	7FD9-mGlu5; mGlu5-LY341495
100.00	Consensus	mglu5_off	Orthosteric Ligand	7FD9-mGlu5; mGlu5-LY341495
100.00	Consensus	mglu_off	Orthosteric Ligand	mglu2_off mglu3_off mglu5_off
100.00	Consensus	mglu_off	Orthosteric Ligand	mglu2_off mglu3_off mglu5_off
100.00	Consensus	mglu_on	Orthosteric Ligand	mglu2_on mglu4_on
100.00	Consensus	mglu_on	Orthosteric Ligand	mglu2_on mglu4_on
100.00	Consensus	smo_off_allo	Other Ligand	6D32-SMO-Cyclopamine-Cyclopamine
100.00	Consensus	tsh_on	Orthosteric Ligand	7T9I-TSH-TSH-Gs/&β;1/&γ;2
100.00	Consensus	tsh_on_allo	Orthosteric Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
50.00	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
50.00	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
50.00	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
50.00	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
50.00	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
50.00	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
50.00	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
50.00	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
50.00	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
50.00	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
33.33	Single	7KNU	Calcitonin gene-related peptide-1	7KNU-CT Like-Calcitonin gene-related peptide-1-RAMP1
33.33	Single	7T9M	CS-17 Antibody	7T9M-TSH-CS-17 Antibody
33.33	Single	8HS2	Fab046	8HS2-GPR20-Fab046
25.00	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
25.00	Single	7FIG	hCG	7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
25.00	Single	7UTZ	TR1402	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
25.00	Single	7XW5	TSH	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
25.00	Single	7ZI0	Cholesterol	7ZI0-SMO-SAG-Cholesterol
20.00	Single	5L7D	Cholesterol	5L7D-SMO-Cholesterol
20.00	Single	7T9I	TSH	7T9I-TSH-TSH-Gs/&β;1/&γ;2
20.00	Single	8HSC	Fab046	8HSC-GPR20-Fab046-Gi1/&β;1/&γ;2
20.00	Single	8I2G	Glycoprotein hormones alpha chain	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
16.67	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
16.67	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Cholesterol-Gi1/&β;1/&γ;2
14.29	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
14.29	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
14.29	Single	6LI0	GTPL9804	6LI0-GPR52-GTPL9804
14.29	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
14.29	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
14.29	Consensus	smo_off_allo	Orthosteric Ligand	6D32-SMO-Cyclopamine-Cyclopamine
12.50	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
12.50	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
12.50	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
12.50	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab-Cholesterol
12.50	Consensus	go_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
12.50	Consensus	go_protein	Orthosteric Ligand	go_chemokine
12.50	Consensus	smo_on_allo	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
11.11	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
11.11	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
11.11	Single	5U09	Taranabant	5U09-CB₁-Taranabant
11.11	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
11.11	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
11.11	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
11.11	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
11.11	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
11.11	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
11.11	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/&β;1/&γ;2
11.11	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
11.11	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/&β;1/&γ;2
11.11	Single	8FN0	Neurotensin/neuromedin N	8FN0-NTS₁-Neurotensin/neuromedin N-PubChem 118610427-chim(NtGi1-Go)/&β;1/&γ;2
11.11	Single	8HMP	PubChem 69921479	8HMP-GPR52-PubChem 69921479-Gs/&β;1/&γ;2
11.11	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
11.11	Consensus	class-f_off	Orthosteric Ligand	smo_off
11.11	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
11.11	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
11.11	Consensus	p2y_off	Orthosteric Ligand	p2y1_off p2y12_off
10.00	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
10.00	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
10.00	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2
10.00	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
10.00	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
10.00	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/&β;1/&γ;2
10.00	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
10.00	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
10.00	Consensus	cb1_off	Orthosteric Ligand	5TGZ-CB₁-AM6538 5U09-CB₁-Taranabant
10.00	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
10.00	Consensus	cxcr_on	Orthosteric Ligand	cxcr1_on cxcr2_on
10.00	Consensus	gi_class-f	Orthosteric Ligand	gi_frizzled
10.00	Consensus	gi_frizzled	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
10.00	Consensus	gnrh_off	Orthosteric Ligand	gnrh1_off
10.00	Consensus	lh_on_allo	Other Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
10.00	Consensus	s1p1_off	Orthosteric Ligand	3V2Y-S1P₁-PubChem 51892645
10.00	Consensus	s1p_off	Orthosteric Ligand	s1p1_off
9.09	Single	4QIM	PubChem 24905375	4QIM-SMO-PubChem 24905375
9.09	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
9.09	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
9.09	Single	6D27	CAY10471	6D27-DP₂-CAY10471
9.09	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2
9.09	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
9.09	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
9.09	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
9.09	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/&β;1/&γ;2
9.09	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
9.09	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
9.09	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
9.09	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/&β;1/&γ;2
9.09	Single	7VIF	(S)-FTY720-P	7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2
9.09	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
9.09	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
9.09	Single	8ID4	Linoleic acid	8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2
9.09	Consensus	fsh_on_allo	Other Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
9.09	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off leuko_off lpl_off paf_off prostanoid_off
9.09	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
9.09	Consensus	smo_off	Orthosteric Ligand	5L7I-SMO-Vismodegib 4O9R-SMO-Cyclopamine 4QIM-SMO-PubChem 24905375 4JKV-SMO-Taladegib (LY2940680)
8.33	Single	4JKV	Taladegib (LY2940680)	4JKV-SMO-Taladegib (LY2940680)
8.33	Single	5C1M	BU72	5C1M-μ-BU72
8.33	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
8.33	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/&β;1/&γ;2
8.33	Single	7BB7	Acyclovir triphosphate	7BB7-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
8.33	Single	7C4S	S1P	7C4S-S1P₃-S1P
8.33	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/&β;1/&γ;2
8.33	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2
8.33	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
8.33	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2
8.33	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
8.33	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
8.33	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
8.33	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
8.33	Single	8FN1	Neurotensin/neuromedin N	8FN1-NTS₁-Neurotensin/neuromedin N-chim(NtGi1-Go)/&β;1/&γ;2
8.33	Single	8JPC	Neurotensin 8-13	8JPC-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
7.69	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
7.69	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
7.69	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
7.69	Single	5V56	TC114	5V56-SMO-TC114
7.69	Single	5V57	TC114	5V57-SMO-TC114
7.69	Single	6OS1	TRV026	6OS1-AT₁-TRV026
7.69	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
7.69	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
7.69	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
7.69	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/&β;1/&γ;2
7.69	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
7.69	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
7.69	Single	7R0C	Acyclovir triphosphate	7R0C-V₂-Acyclovir triphosphate-Arrestin2
7.69	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
7.69	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/&β;1/&γ;2
7.69	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2
7.69	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
7.69	Single	8E0G	BU72	8E0G-μ-BU72
7.69	Single	8FMZ	Neurotensin/neuromedin N	8FMZ-NTS₁-Neurotensin/neuromedin N-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7.69	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
7.69	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
7.69	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2
7.69	Single	8ID6	Oleic acid	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2
7.69	Consensus	arrestin2	Orthosteric Ligand	6TKO-β₁-Arformoterol-Arrestin2 6PWC-NTS₁-Neurotensin-Arrestin2 7R0C-V₂-Acyclovir triphosphate-Arrestin2
7.69	Consensus	class-a_off	Orthosteric Ligand	sensory_off amine_off lipid_off nucleotide_off peptide_off protein_off hcar_off
7.69	Consensus	lpa1_on	Orthosteric Ligand	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
7.69	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
7.69	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
7.69	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
7.69	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
7.14	Single	4GRV	Neurotensin 8-13	4GRV-NTS₁-Neurotensin 8-13
7.14	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
7.14	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
7.14	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/&β;1/&γ;2
7.14	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
7.14	Single	6OS2	TRV026	6OS2-AT₁-TRV026
7.14	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/&β;1/&γ;2
7.14	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2
7.14	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
7.14	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/&β;1/&γ;2
7.14	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
7.14	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/&β;1/γ1
7.14	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
7.14	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
7.14	Single	8IBU	Erythromycin A	8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7.14	Single	8JPB	Neurotensin 8-13	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
7.14	Single	8T3Q	DHA	8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7.14	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2
7.14	Consensus	cannabinoid_off	Orthosteric Ligand	cb1_off cb2_off
7.14	Consensus	chemokine_off	Orthosteric Ligand	cxcr_off
7.14	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II
7.14	Consensus	cxcr_off	Orthosteric Ligand	cxcr4_off
7.14	Consensus	dp2_off	Orthosteric Ligand	6D27-DP₂-CAY10471 6D26-DP₂-Fevipiprant
7.14	Consensus	dp_off	Orthosteric Ligand	dp2_off
7.14	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z34-LPA₁-ONO-9780307 4Z35-LPA₁-ONO-9910539 7YU4-LPA₁-ONO-0740556
7.14	Consensus	mop_on	Orthosteric Ligand	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
7.14	Consensus	nts1_on	Orthosteric Ligand	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
7.14	Consensus	nts_on	Orthosteric Ligand	nts1_on
7.14	Consensus	s1p_on	Orthosteric Ligand	s1p3_on s1p5_on s1p1_on s1p2_on
7.14	Consensus	tsh_on_allo	Other Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
6.67	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
6.67	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
6.67	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
6.67	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/&β;1/&γ;2
6.67	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
6.67	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2
6.67	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2
6.67	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2
6.67	Single	7P00	Substance P	7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.67	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/&β;1/&γ;2
6.67	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
6.67	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/&β;1/&γ;2
6.67	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
6.67	Consensus	class-a_on	Orthosteric Ligand	sensory_on amine_on lipid_on nucleotide_on peptide_on protein_on hcar_on steroid_on melatonin_on
6.67	Consensus	gi_class-a	Orthosteric Ligand	gi_amine gi_lipid gi_melatonin gi_peptide gi_protein gi_nucleotide gi_hcar
6.67	Consensus	gi_neurotensin	Orthosteric Ligand	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1 6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
6.67	Consensus	s1p1_on	Orthosteric Ligand	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
6.25	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
6.25	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/&β;1/&γ;2
6.25	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/&β;1/&γ;2
6.25	Single	7RMG	Substance P	7RMG-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
6.25	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
6.25	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/&β;1/&γ;2
6.25	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
6.25	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.25	Consensus	chemokine_on	Orthosteric Ligand	cxcr_on cx3cr_on
6.25	Consensus	gi_apelin	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
6.25	Consensus	go_compl-peptide	Orthosteric Ligand	8I95-C3a_B-EP54-Go/&β;1/&γ;2 8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2 8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2
6.25	Consensus	go_ghrelin	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
6.25	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
6.25	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
6.25	Consensus	mc4_on	Orthosteric Ligand	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
6.25	Consensus	motilin_on	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.25	Consensus	nk1_on	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.25	Consensus	protein_on	Orthosteric Ligand	ccr_on chemokine_on gphr_on chemerin_on
5.88	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
5.88	Single	5VBL	Apelin Mimetic Peptide Agonist	5VBL-Apelin-Apelin Mimetic Peptide Agonist
5.88	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2
5.88	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
5.88	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
5.88	Single	7RMH	Substance P	7RMH-NK₁-Substance P-Gs/&β;1/&γ;2
5.88	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2
5.88	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2
5.88	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/&β;1/&γ;2
5.88	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2
5.88	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2
5.88	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/&β;1/&γ;2
5.88	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/&β;1/&γ;2
5.88	Consensus	apelin_on	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
5.88	Consensus	gi_opioid	Orthosteric Ligand	8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 7U2K-μ-C6-guano-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2 8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 7SCG-μ-FH210-Gi1/&β;1/&γ;2 7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2 7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2 7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
5.88	Consensus	go_class-a	Orthosteric Ligand	go_amine go_peptide go_protein
5.88	Consensus	protein_off	Orthosteric Ligand	ccr_off chemokine_off gnrh_off
5.56	Single	6DO1	Angiotensin-Like peptide S1I8	6DO1-AT₁-Angiotensin-Like peptide S1I8
5.56	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
5.56	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
5.56	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/&β;1/&γ;2
5.56	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
5.56	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2
5.56	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/&β;1/&γ;2
5.56	Single	7RMI	Substance P	7RMI-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
5.56	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
5.56	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2
5.56	Single	8F7Q	Beta-endorphin	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2
5.56	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.56	Single	8IOC	Gamma-MSH	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
5.56	Consensus	gi_lpl	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2 7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
5.56	Consensus	vasopressin-ot_on	Orthosteric Ligand	ot_on v2_on
5.26	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
5.26	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
5.26	Single	7O7F	(6P4)CCL5	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1
5.26	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2
5.26	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/&β;1/&γ;2
5.26	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/&β;1/&γ;2
5.26	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
5.26	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/&β;1/&γ;2
5.26	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
5.26	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
5.26	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
5.26	Consensus	ccr_off	Orthosteric Ligand	ccr5_off ccr8_off
5.26	Consensus	go_peptide	Orthosteric Ligand	go_opioid go_ghrelin go_compl-peptide go_galanin go_vasopressin
5.26	Consensus	gs_class-a	Orthosteric Ligand	gs_amine gs_nucleotide gs_lipid gs_peptide gs_protein gs_steroid
5.26	Consensus	gs_motilin	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.26	Consensus	gs_tachykinin	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.26	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
5.26	Consensus	opioid_on	Orthosteric Ligand	kop_on mop_on nop_on dop_on
5.26	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on
5.00	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
5.00	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
5.00	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
5.00	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
5.00	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
5.00	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/&β;1/&γ;2
5.00	Single	7DW9	Acyclovir triphosphate	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
5.00	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
5.00	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
5.00	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2
5.00	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
5.00	Single	7YON	Peptide YY(3-36)	7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
5.00	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.00	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
5.00	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/&β;1/&γ;2
5.00	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
5.00	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/&β;1/&γ;2
5.00	Consensus	bk2_on	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
5.00	Consensus	ccr1_on	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
5.00	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
5.00	Consensus	ghrelin_on	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
5.00	Consensus	go_class-b	Orthosteric Ligand	go_class-b1 go_class-b2
5.00	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
5.00	Consensus	pca1_on	Orthosteric Ligand	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
5.00	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
4.76	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
4.76	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2
4.76	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2
4.76	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
4.76	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.76	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/&β;1/&γ;2
4.76	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/&β;1/&γ;2
4.76	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/&β;1/&γ;2
4.76	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
4.76	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/&β;1/&γ;2
4.76	Single	7X9B	Neuropeptide Y	7X9B-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
4.76	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2
4.76	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
4.76	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2
4.76	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2
4.76	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.76	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2
4.76	Consensus	c5a1_on	Orthosteric Ligand	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2 8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
4.76	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
4.76	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.76	Consensus	gq_class-a	Orthosteric Ligand	gq_amine gq_peptide
4.76	Consensus	gs_ghrelin	Orthosteric Ligand	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.76	Consensus	vpac1_on	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
4.55	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
4.55	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
4.55	Single	6FJ3	PTH	6FJ3-PTH1-PTH
4.55	Single	6NBF	Long-acting PTH analog	6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
4.55	Single	6NBI	Long-acting PTH analog	6NBI-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
4.55	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
4.55	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2
4.55	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/&β;1/&γ;2
4.55	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
4.55	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
4.55	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
4.55	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
4.55	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/&β;1/&γ;2
4.55	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
4.55	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
4.55	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2
4.55	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on bk1_on
4.55	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
4.55	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
4.55	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
4.55	Consensus	gi_compl-peptide	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2 7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
4.55	Consensus	glp1_on_allo	Orthosteric Ligand	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
4.55	Consensus	gs_vasopressin-ot	Orthosteric Ligand	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
4.55	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
4.35	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
4.35	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2
4.35	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/&β;1/&γ;2; RAMP3
4.35	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
4.35	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/&β;1/&γ;2
4.35	Single	7F53	Alpha-MSH	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2
4.35	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2
4.35	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
4.35	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
4.35	Single	7YOO	Neuropeptide Y	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
4.35	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
4.35	Consensus	ccr8_on	Orthosteric Ligand	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
4.35	Consensus	ccr_on	Orthosteric Ligand	ccr5_on ccr6_on ccr1_on ccr2_on ccr8_on
4.35	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
4.35	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
4.35	Consensus	go_class-b1	Orthosteric Ligand	go_crf
4.35	Consensus	go_crf	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
4.35	Consensus	gs_cgrp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
4.17	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2
4.17	Single	6LML	Glucagon	6LML-Glucagon-Glucagon
4.17	Single	6NBH	Long-acting PTH analog	6NBH-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
4.17	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP3
4.17	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
4.17	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
4.17	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2
4.17	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP1
4.17	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/&β;1/&γ;2
4.17	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/&β;1/&γ;2
4.17	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/&β;1/&γ;2
4.17	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2
4.17	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
4.17	Consensus	calcitonin_on	Orthosteric Ligand	ct_on ctlike_on
4.17	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
4.17	Consensus	gi_chemokine	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2 7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2 7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2 7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2 8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2 6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2 8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
4.17	Consensus	glp1_on	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2 6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2 7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2 8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
4.17	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
4.17	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_angiotensin gq_bombesin gq_bradykinin
4.17	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_motilin gs_neuromedin gs_orexin gs_sst gs_tachykinin gs_trh gs_vasopressin-ot gs_bombesin gs_bradykinin gs_compl-peptide gs_endothelin gs_galanin gs_ghrelin gs_melanocortin
4.17	Consensus	peptide_on	Orthosteric Ligand	opioid_on angiotensin_on bombesin_on cck_on endothelin_on ghrelin_on npy_on nts_on orexin_on vasopressin-ot_on tachykinin_on sst_on relaxin_on trh_on nmur_on motilin_on melanocortin_on galanin_on fpr-alx_on compl-peptide_on bradykinin_on apelin_on
4.17	Consensus	secretin_on	Orthosteric Ligand	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
4.17	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
4.00	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
4.00	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/&β;1/&γ;2
4.00	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
4.00	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
4.00	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
4.00	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
4.00	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/&β;1/&γ;2; RAMP1
4.00	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/&β;1/&γ;2
4.00	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/&β;1/&γ;2
4.00	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2
4.00	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/&β;1/&γ;2; RAMP2
4.00	Consensus	gi_peptide	Orthosteric Ligand	gi_opioid gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_neuromedin gi_neurotensin gi_relaxin gi_neuropeptide gi_somatostatin gi_apelin gi_compl-peptide gi_cck
4.00	Consensus	gip_on	Orthosteric Ligand	7DTY-GIP-GIP-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
4.00	Consensus	gip_on_allo	Orthosteric Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
3.85	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/&β;1/&γ;1
3.85	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
3.85	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
3.85	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
3.85	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2
3.85	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/&β;1/&γ;2
3.85	Single	8FLU	Long-acting PTH	8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2
3.85	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
3.85	Consensus	melanocortin_on	Orthosteric Ligand	mc2_on mc1_on mc3_on mc4_on mc5_on
3.70	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
3.70	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/&β;1/&γ;2; RAMP3
3.70	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2
3.70	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/&β;1/&γ;2
3.70	Single	8F0K	Pramlintide analogue san385	8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
3.70	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2
3.70	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2
3.70	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
3.70	Consensus	pth1_on	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2
3.70	Consensus	vip-pacap_on	Orthosteric Ligand	vpac1_on vpac2_on pca1_on
3.57	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
3.57	Single	7X9A	Neuropeptide Y	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
3.57	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2
3.57	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2
3.57	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2
3.57	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
3.57	Consensus	gi_neuropeptide	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2 7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2 7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
3.57	Consensus	gs_glucagon	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 6WZG-Secretin-Secretin-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2 7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2 7DTY-GIP-GIP-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
3.57	Consensus	gs_vip-pacap	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
3.57	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
3.57	Consensus	npy1_on	Orthosteric Ligand	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
3.57	Consensus	npy_on	Orthosteric Ligand	npy2_on npy4_on npy1_on
3.57	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
3.45	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
3.45	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
3.45	Consensus	gs_class-b	Orthosteric Ligand	gs_class-b1 gs_class-b2
3.45	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
3.33	Single	8F2A	Pramlintide analogue san385	8F2A-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
3.33	Consensus	ct_on	Orthosteric Ligand	7TYL-CT-Amylin-Gs/&β;1/&γ;2 7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
3.23	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
3.23	Consensus	glucagon_on	Orthosteric Ligand	gip_on glu_on secretin_on ghrh_on glp_on
3.23	Consensus	gs_pth	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7F16-PTH2-TIP39-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
3.12	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/&β;1/&γ;2
3.12	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on calcitonin_on vip-pacap_on pth_on crf_on
3.12	Consensus	glu_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2 6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2 8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2 8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2 7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2 6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
3.03	Single	8F2B	Pramlintide analogue san45	8F2B-CT (AMY3)-Pramlintide analogue san45-Gs/&β;1/&γ;2; RAMP3
3.03	Consensus	gs_calcitonin	Orthosteric Ligand	gs_ct gs_cgrp
3.03	Consensus	gs_ct	Orthosteric Ligand	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 7TYL-CT-Amylin-Gs/&β;1/&γ;2 8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
2.94	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
2.94	Consensus	gs_class-b1	Orthosteric Ligand	gs_glucagon gs_vip-pacap gs_pth gs_calcitonin gs_crf
2.86	Single	8F0J	Pramlintide analogue san45	8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2

Consensus Members
	Id	Members
	7FIG	7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2

Net Summary
I_min	4.3
Number of Linked Nodes	548
Number of Links	641
Number of Hubs	85
Number of Links mediated by Hubs	348
Number of Communities	17
Number of Nodes involved in Communities	103
Number of Links involved in Communities	140

Path Summary
Number Of Nodes in MetaPath	87
Number Of Links MetaPath	86
Number of Shortest Paths	439130
Length Of Smallest Path	3
Average Path Length	23.7252
Length of Longest Path	50
Minimum Path Strength	1.24
Average Path Strength	8.54776
Maximum Path Strength	26.58
Minimum Path Correlation	0.71
Average Path Correlation	0.977516
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	4
Average % Of Corr. Nodes	58.9295
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	40.1829
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

This network is also present in following differences:
	Id	1^st Network	2^nd Network
	lh_on_ortoallo	lh_on_allo	lh_on

This network is also present in following consensuses:
	Id	Components
	gphr_on	lh_on tsh_on

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