psnGPCR

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Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	G.HN.33	G.HN.37	3.73939	No	No	0	4	3
2	G.HN.36	b.b4x7	8.00945	No	Yes	4	4	8
3	G.HN.36	b.l4x3	5.79558	No	No	4	4	6
4	G.HN.36	b.b5x2	10.5067	No	Yes	4	4	7
5	G.HN.37	b.b5x2	3.89466	No	Yes	0	3	7
6	G.HN.40	G.HN.44	8.88223	No	No	4	7	6
7	G.HN.40	b.b5x2	11.6306	No	Yes	4	7	7
8	G.HN.40	b.b5x3	5.62303	No	Yes	4	7	9
9	G.HN.43	b.b5x3	6.37931	No	Yes	0	9	9
10	G.HN.43	b.b5x6	3.4839	No	No	0	9	6
11	G.HN.44	b.b5x3	6.74936	No	Yes	4	6	9
12	G.HN.46	G.HN.50	7.2012	No	No	0	4	5
13	G.HN.47	b.b4x2	3.51761	No	Yes	0	5	8
14	G.HN.48	G.HN.51	3.72186	No	No	0	4	4
15	G.HN.50	b.b4x2	5.86474	No	Yes	0	5	8
16	G.HN.51	G.hns1.02	5.39401	No	No	0	4	4
17	G.HN.51	b.l1x4	6.53501	No	No	0	4	6
18	G.hns1.01	G.hns1.02	3.5092	Yes	No	0	4	4
19	G.S1.03	G.hns1.01	20.0617	No	Yes	0	9	4
20	G.hns1.01	b.l1x4	5.59511	Yes	No	14	4	6
21	G.hns1.01	b.l1x5	3.22037	Yes	No	0	4	7
22	G.hns1.01	b.l3x2	4.22543	Yes	Yes	14	4	9
23	G.S1.01	G.S3.02	3.4876	No	No	0	7	4
24	G.S1.01	G.S3.04	3.25122	No	Yes	0	7	7
25	G.S1.02	G.S3.03	6.47506	Yes	Yes	3	6	8
26	G.S1.02	G.h2s4.05	6.93224	Yes	No	0	6	8
27	G.H5.15	G.S1.02	4.45258	No	Yes	3	8	6
28	G.S1.03	G.S3.06	3.49086	No	Yes	0	9	7
29	G.S1.04	G.S3.03	3.47711	No	Yes	0	7	8
30	G.S1.04	G.S4.03	3.94464	No	No	0	7	7
31	G.S1.05	G.S1.07	3.37088	No	No	0	9	8
32	G.S1.05	G.h2s4.01	19.0894	No	Yes	0	9	9
33	G.S1.05	G.S4.02	7.3915	No	No	0	9	8
34	G.S1.06	G.S3.05	7.8643	No	No	0	8	8
35	G.S1.06	G.S3.07	4.65748	No	Yes	0	8	9
36	G.S1.07	G.S4.04	3.19318	No	Yes	0	8	9
37	G.H3.01	G.s1h1.04	4.4647	Yes	Yes	0	9	9
38	G.H1.01	G.S3.07	6.67901	No	Yes	0	9	9
39	G.hfs2.07	b.l7x4	4.71885	No	No	0	8	9
40	G.S2.01	G.S3.06	3.95995	No	Yes	0	9	7
41	G.S2.03	G.S3.04	10.3129	No	Yes	15	9	7
42	G.S2.03	G.S3.06	8.58569	No	Yes	15	9	7
43	G.S2.04	G.S3.05	4.6651	No	No	0	7	8
44	G.S2.05	G.S3.04	16.1093	No	Yes	0	4	7
45	G.S2.06	G.S3.03	11.4155	No	Yes	0	9	8
46	G.S2.07	G.S3.02	7.45171	No	No	0	3	4
47	G.S2.08	G.s2s3.01	3.15708	No	No	3	6	5
48	G.H5.05	G.S2.08	3.98304	Yes	No	3	5	6
49	G.H5.08	G.S2.08	10.094	Yes	No	3	8	6
50	G.H5.05	G.s2s3.01	8.43047	Yes	No	3	5	5
51	G.H5.08	G.s2s3.01	6.16547	Yes	No	3	8	5
52	G.S3.01	G.S3.03	4.7074	No	Yes	3	5	8
53	G.H5.08	G.S3.01	3.48585	Yes	No	3	8	5
54	G.H5.08	G.S3.03	5.3876	Yes	Yes	3	8	8
55	G.H5.11	G.S3.03	4.26438	No	Yes	0	8	8
56	G.S3.04	G.S3.06	13.7107	Yes	Yes	15	7	7
57	G.S3.06	b.l5x5	18.1519	Yes	Yes	0	7	9
58	G.H2.07	G.S3.08	9.91124	Yes	No	0	9	9
59	G.H2.07	G.s3h2.03	4.53235	Yes	No	2	9	9
60	G.s3h2.03	b.l7x4	5.06503	No	No	0	9	9
61	G.s3h2.03	b.l9x6	7.67006	No	Yes	2	9	8
62	G.H2.01	G.H2.03	11.6868	No	No	2	9	9
63	G.H2.01	b.b12x1	4.55699	No	No	0	9	6
64	G.H2.01	b.l13x6	8.03433	No	Yes	2	9	9
65	G.H2.03	G.H2.05	7.30937	No	No	2	9	8
66	G.H2.04	G.H2.07	9.14238	No	Yes	0	9	9
67	G.H2.04	G.H3.08	8.78099	No	Yes	0	9	8
68	G.H2.05	b.l15x1	4.5087	No	Yes	2	8	7
69	G.H2.05	b.l17x6	11.4481	No	Yes	2	8	9
70	G.H2.06	b.l9x6	3.61482	Yes	Yes	2	9	8
71	G.H2.06	b.b14x1	10.4832	Yes	No	2	9	8
72	G.H2.06	b.l15x1	5.17933	Yes	Yes	2	9	7
73	G.H2.06	b.l17x6	7.67852	Yes	Yes	2	9	9
74	G.H2.06	b.b18x1	4.71519	Yes	No	2	9	9
75	G.H2.06	b.l19x1	4.18517	Yes	Yes	2	9	9
76	G.H2.07	G.H2.08	3.61798	Yes	No	0	9	9
77	G.H2.07	G.h2s4.01	3.1865	Yes	Yes	0	9	9
78	G.H2.07	b.l9x6	4.51882	Yes	Yes	2	9	8
79	G.H2.08	G.H3.18	3.19517	No	No	0	9	9
80	G.H2.09	G.H3.17	5.91279	No	Yes	2	8	5
81	G.H2.09	b.l25x6	5.5211	No	Yes	2	8	8
82	G.H2.10	b.b2x1	5.1092	No	Yes	2	8	8
83	G.H2.10	b.l3x1	4.90241	No	Yes	2	8	9
84	G.H2.10	b.b6x1	4.67794	No	Yes	2	8	9
85	G.h2s4.01	G.h2s4.04	3.51205	Yes	No	0	9	9
86	G.h2s4.01	b.l5x5	12.922	Yes	Yes	0	9	9
87	G.h2s4.02	G.h2s4.03	5.57457	No	No	2	8	6
88	G.h2s4.02	b.l1x6	8.45679	No	Yes	2	8	9
89	G.h2s4.02	b.l28x1	7.93421	No	Yes	2	8	9
90	G.h2s4.03	b.l1x6	7.71542	No	Yes	2	6	9
91	G.S4.01	G.S5.03	3.25	No	No	0	8	9
92	G.S4.02	G.h3s5.03	3.35221	No	No	0	8	7
93	G.H5.07	G.S4.03	3.27269	No	No	0	9	7
94	G.H3.08	G.S4.04	6.85575	Yes	Yes	0	8	9
95	G.H3.09	G.S4.04	3.61193	Yes	Yes	0	9	9
96	G.S4.04	G.S5.04	3.41485	Yes	No	0	9	9
97	G.S4.05	G.S5.07	3.28051	No	Yes	0	7	9
98	G.H4.15	G.S4.06	5.85071	Yes	No	0	8	7
99	G.H3.03	G.s4h3.15	5.77531	No	No	0	4	9
100	G.hgh4.01	G.s4h3.15	13.6743	Yes	No	0	6	9
101	G.H3.02	G.hgh4.02	4.7656	No	No	0	8	8
102	G.H3.02	G.H4.11	5.28446	No	No	0	8	8
103	G.H3.03	G.H3.06	3.25027	No	No	0	4	6
104	G.H3.03	G.H3.07	3.36847	No	No	0	4	5
105	G.H3.06	G.H4.14	4.28356	No	Yes	0	6	5
106	G.H3.06	G.H4.15	10.1605	No	Yes	0	6	8
107	G.H3.08	G.H3.12	3.36881	Yes	No	0	8	8
108	G.H3.09	G.H3.13	5.9007	Yes	Yes	16	9	6
109	G.H3.09	G.S5.02	4.92281	Yes	No	16	9	6
110	G.H3.09	G.H4.15	7.69898	Yes	Yes	0	9	8
111	G.H3.09	G.h4s6.01	5.62188	Yes	No	0	9	4
112	G.H3.09	G.S6.01	3.47477	Yes	No	0	9	5
113	G.H3.10	G.H3.14	6.36398	No	No	0	5	8
114	G.H3.10	G.h4s6.01	7.61386	No	No	0	5	4
115	G.H3.12	G.H3.18	3.08287	No	No	0	8	9
116	G.H3.13	G.S5.02	3.6597	Yes	No	16	6	6
117	G.H3.13	G.h4s6.02	7.55059	Yes	No	0	6	7
118	G.H3.13	G.h4s6.13	26.1334	Yes	No	0	6	7
119	G.H3.14	G.h4s6.08	3.15029	No	No	0	8	5
120	G.H3.15	G.H3.18	11.5291	No	No	0	8	9
121	G.H3.16	G.H3.17	15.3479	No	Yes	0	5	5
122	G.H3.17	b.l23x1	8.8524	Yes	Yes	2	5	6
123	G.H3.17	b.l25x6	17.7324	Yes	Yes	2	5	8
124	G.H3.17	b.l28x1	5.59773	Yes	Yes	2	5	9
125	G.h3s5.01	G.h4s6.12	6.09955	No	Yes	0	3	2
126	G.h3s5.02	G.h4s6.12	3.45407	No	Yes	0	4	2
127	G.H5.14	G.S5.01	8.90693	No	No	0	6	8
128	G.S5.03	G.S5.05	3.38937	No	Yes	0	9	9
129	G.H5.10	G.S5.03	8.33683	No	No	0	7	9
130	G.S5.04	G.S5.06	4.11028	No	No	0	9	8
131	G.H4.15	G.S5.04	8.24497	Yes	No	0	8	9
132	G.S5.05	G.S6.04	4.94966	Yes	No	0	9	9
133	G.S5.05	G.s6h5.01	5.83969	Yes	No	18	9	9
134	G.H5.03	G.S5.05	4.21101	Yes	Yes	18	9	9
135	G.S5.06	G.S6.05	3.68029	No	Yes	0	8	5
136	G.S5.07	G.s6h5.01	3.80701	Yes	No	0	9	9
137	G.HG.03	G.s5hg.01	4.042	No	No	0	6	9
138	G.H4.07	G.HG.01	6.3911	No	No	8	5	6
139	G.HG.01	G.S6.05	5.54591	No	Yes	8	6	5
140	G.HG.15	G.hgh4.05	6.41972	No	Yes	0	7	6
141	G.HG.16	G.hgh4.05	3.37718	No	Yes	0	4	6
142	G.HG.17	G.hgh4.01	7.48682	No	Yes	0	3	6
143	G.H4.10	G.hgh4.02	6.65767	Yes	No	0	7	8
144	G.H4.10	G.hgh4.04	4.40939	Yes	Yes	17	7	6
145	G.H4.14	G.hgh4.04	3.60378	Yes	Yes	17	5	6
146	G.H4.05	G.hgh4.05	14.8636	No	Yes	0	5	6
147	G.H4.10	G.hgh4.05	15.1559	Yes	Yes	0	7	6
148	G.hgh4.08	G.hgh4.11	5.37731	Yes	Yes	0	6	5
149	G.H4.05	G.hgh4.08	3.5829	No	Yes	0	5	6
150	G.H4.10	G.hgh4.08	12.467	Yes	Yes	0	7	6
151	G.H4.13	G.hgh4.08	8.77079	No	Yes	0	3	6
152	G.hgh4.10	G.hgh4.11	3.48	No	Yes	0	1	5
153	G.H4.05	G.hgh4.10	4.01904	No	No	0	5	1
154	G.H4.08	G.hgh4.11	4.52962	Yes	Yes	0	3	5
155	G.H4.08	G.hgh4.14	7.6225	Yes	No	0	3	3
156	G.H4.04	G.hgh4.16	4.70576	No	No	0	4	1
157	G.hgh4.17	G.hgh4.18	3.95369	No	No	0	4	1
158	G.hgh4.17	G.hgh4.20	7.31125	No	Yes	0	4	3
159	G.H4.03	G.hgh4.20	3.90814	Yes	Yes	0	4	3
160	G.H4.04	G.hgh4.20	6.76122	No	Yes	0	4	3
161	G.H4.07	G.hgh4.20	7.29514	No	Yes	0	5	3
162	G.H4.01	G.hgh4.21	5.09603	No	Yes	0	1	4
163	G.H4.02	G.hgh4.21	5.99966	No	Yes	0	5	4
164	G.H4.03	G.hgh4.21	3.77097	Yes	Yes	0	4	4
165	G.H4.07	G.S6.05	13.3263	No	Yes	8	5	5
166	G.H4.08	G.H4.12	8.04637	Yes	Yes	8	3	4
167	G.H4.08	G.S6.05	5.70366	Yes	Yes	8	3	5
168	G.H4.10	G.H4.14	9.4476	Yes	Yes	17	7	5
169	G.H4.12	G.H4.13	3.94755	Yes	No	0	4	3
170	G.H4.12	G.H4.16	5.68407	Yes	No	8	4	4
171	G.H4.12	G.S6.03	5.68162	Yes	No	8	4	5
172	G.H4.12	G.S6.05	4.57602	Yes	Yes	8	4	5
173	G.H4.14	G.H4.17	10.0966	Yes	No	0	5	4
174	G.H4.16	G.S6.03	4.70359	No	No	8	4	5
175	G.S6.01	G.h4s6.02	5.27781	No	No	0	5	7
176	G.h4s6.10	G.h4s6.12	8.12041	No	Yes	0	3	2
177	G.h4s6.12	G.h4s6.13	4.42961	Yes	No	0	2	7
178	G.S6.02	G.h4s6.20	5.68916	Yes	Yes	0	8	4
179	G.H5.17	G.h4s6.20	13.3261	Yes	Yes	0	5	4
180	G.H5.10	G.S6.02	14.5573	No	Yes	0	7	8
181	G.H5.13	G.S6.02	10.5357	No	Yes	0	8	8
182	G.H5.14	G.S6.02	7.18415	No	Yes	0	6	8
183	G.H5.06	G.S6.04	10.1928	No	No	0	4	9
184	G.H5.10	G.S6.04	11.6357	No	No	0	7	9
185	G.H5.03	G.s6h5.01	5.39853	Yes	No	18	9	9
186	G.s6h5.02	G.s6h5.05	3.59946	No	No	0	8	9
187	G.H5.03	G.s6h5.05	3.21631	Yes	No	0	9	9
188	G.H5.02	G.H5.06	4.67037	No	No	0	4	4
189	G.H5.03	G.H5.06	4.37329	Yes	No	0	9	4
190	G.H5.05	G.H5.08	4.11263	Yes	Yes	3	5	8
191	G.H5.05	G.H5.09	5.42886	Yes	No	0	5	4
192	G.H5.12	G.H5.16	4.95883	No	No	3	7	6
193	G.H5.13	G.H5.17	10.3836	No	Yes	3	8	5
194	5x68	G.H5.13	8.23277	No	No	3	9	8
195	G.H5.15	G.H5.19	3.49768	No	Yes	0	8	8
196	5x68	G.H5.16	6.53417	No	No	3	9	6
197	G.H5.17	G.H5.26	3.17261	Yes	No	0	5	8
198	5x68	G.H5.17	8.3002	No	Yes	3	9	5
199	G.H5.18	G.H5.19	3.52219	No	Yes	0	3	8
200	G.H5.18	G.H5.22	3.91032	No	No	0	3	4
201	3x53	G.H5.19	11.9094	No	Yes	0	8	8
202	G.H5.20	G.H5.25	4.0572	Yes	No	0	8	8
203	G.H5.20	G.H5.26	6.27294	Yes	No	0	8	8
204	3x54	G.H5.20	4.71086	No	Yes	0	8	8
205	2x39	G.H5.22	5.00218	Yes	No	0	9	4
206	2x39	G.H5.23	9.21229	Yes	No	0	9	4
207	3x49	G.H5.23	3.4066	Yes	No	0	8	4
208	3x50	G.H5.23	10.3314	No	No	0	9	4
209	8x47	G.H5.24	6.3052	No	No	0	9	6
210	6x40	G.H5.25	4.39734	No	No	0	9	8
211	b.1x3	b.ntx1	4.19719	No	No	0	1	5
212	b.1x7	g.h1x8	4.99888	No	No	0	8	7
213	b.1x12	b.1x9	3.52946	No	No	0	6	4
214	b.1x11	g.h1x11	4.44924	No	No	0	8	9
215	b.1x13	b.1x16	3.95787	No	No	0	1	4
216	b.1x15	b.1x19	4.55476	No	No	0	7	6
217	b.1x18	g.l1x4	3.60179	No	Yes	0	4	8
218	b.1x19	b.b21x1	8.36776	No	Yes	0	6	7
219	b.1x19	b.b21x2	4.75314	No	No	0	6	6
220	b.b21x2	b.lh12x1	3.58474	No	No	0	6	3
221	b.lh12x2	g.l1x6	9.65712	No	No	0	8	4
222	b.lh12x2	g.h2x2	5.65272	No	No	0	8	9
223	b.h2x3	b.lh12x4	8.37432	No	No	0	1	3
224	b.h2x1	b.h2x5	3.1982	Yes	Yes	0	5	5
225	b.b21x4	b.h2x1	3.80288	No	Yes	0	5	5
226	b.b21x5	b.h2x1	6.90591	Yes	Yes	0	4	5
227	b.h2x5	b.lhb1x3	3.48659	Yes	Yes	0	5	2
228	b.h2x5	b.l24x2	4.31167	Yes	No	0	5	6
229	b.l22x5	b.lhb1x3	4.84086	Yes	Yes	0	9	2
230	b.l24x3	b.lhb1x3	4.55029	Yes	Yes	0	5	2
231	b.l22x5	b.lhb1x6	7.1706	Yes	Yes	12	9	3
232	b.b24x7	b.lhb1x6	7.37399	No	Yes	12	9	3
233	b.lhb1x6	g.ctx6	3.13964	Yes	Yes	12	3	6
234	b.b23x1	b.lhb1x9	3.25106	Yes	No	0	5	3
235	b.b25x7	b.lhb1x11	5.91591	Yes	No	0	7	4
236	b.lhb1x11	g.ctx5	4.77997	No	No	0	4	9
237	b.b1x1	b.b1x3	9.45938	No	Yes	0	5	7
238	b.b1x2	b.b28x4	6.36688	No	Yes	10	3	6
239	b.b1x2	b.b28x6	9.2171	No	Yes	10	3	9
240	b.b1x3	b.b28x7	7.29205	Yes	No	0	7	9
241	b.b1x4	b.b5x1	4.49593	Yes	No	0	7	5
242	b.b1x4	b.b28x5	5.21576	Yes	No	7	7	5
243	b.b1x4	g.ctx16	6.16092	Yes	Yes	7	7	8
244	b.b1x5	b.l1x1	10.5171	No	No	0	3	7
245	b.b1x5	b.b28x4	7.37533	No	Yes	0	3	6
246	b.b1x6	b.b4x6	19.6483	No	Yes	4	9	9
247	b.b1x6	b.b28x3	7.68699	No	Yes	4	9	7
248	b.b28x2	b.l1x1	8.28656	No	No	0	4	7
249	I1x48	b.l1x1	10.6202	No	No	0	8	7
250	b.l1x3	b.l1x7	9.68805	Yes	No	0	9	9
251	b.b3x4	b.l1x3	7.95715	No	Yes	4	9	9
252	b.b3x6	b.l1x3	11.5651	No	Yes	0	9	9
253	b.b4x4	b.l1x3	12.7721	No	Yes	4	8	9
254	b.b4x6	b.l1x3	4.25175	Yes	Yes	4	9	9
255	b.l1x4	b.l3x2	10.7683	No	Yes	14	6	9
256	b.b2x1	b.l1x6	6.28824	Yes	Yes	2	8	9
257	b.l1x6	b.l3x1	9.28226	Yes	Yes	2	9	9
258	b.l1x6	b.l28x1	21.7386	Yes	Yes	2	9	9
259	b.b28x3	b.l1x7	4.40988	Yes	No	0	7	9
260	b.b2x1	b.l3x1	14.0985	Yes	Yes	2	8	9
261	b.b2x1	b.b6x1	5.89745	Yes	Yes	2	8	9
262	b.b2x1	b.l28x1	8.06874	Yes	Yes	2	8	9
263	b.b2x3	b.b2x5	5.68297	No	Yes	4	6	7
264	b.b2x3	b.b3x2	3.14134	No	No	4	6	5
265	b.b26x2	b.b2x3	4.9464	No	No	0	7	6
266	b.b2x4	b.b6x5	3.11065	No	Yes	0	6	6
267	b.b10x4	b.b2x4	15.6486	No	No	0	6	6
268	b.b2x5	b.b3x2	9.08668	Yes	No	4	7	5
269	b.b2x5	b.l4x1	5.05553	Yes	No	0	7	5
270	b.b2x5	b.l27x1	11.1512	Yes	No	4	7	7
271	b.b27x2	b.b2x5	4.43943	No	Yes	0	5	7
272	b.b6x5	b.l2x1	3.964	Yes	No	0	6	5
273	b.l2x3	b.l2x5	4.62706	No	No	0	8	5
274	b.b3x1	b.l2x3	4.20862	No	No	0	5	8
275	b.l27x1	b.l2x4	7.04585	No	No	4	7	5
276	b.l27x3	b.l2x4	9.90895	No	No	4	7	5
277	b.b4x7	b.l2x5	15.6424	Yes	No	0	8	5
278	b.l2x5	b.l4x2	20.5904	No	No	0	5	4
279	b.b3x1	b.b4x7	3.94361	No	Yes	0	5	8
280	b.b3x1	b.b6x5	3.29937	No	Yes	0	5	6
281	b.b3x2	b.b4x6	5.40165	No	Yes	4	5	9
282	b.b3x3	b.b4x3	3.42913	Yes	Yes	9	8	7
283	b.b3x3	b.b4x5	3.41735	Yes	No	0	8	7
284	b.b3x3	b.b6x3	3.47622	Yes	No	0	8	8
285	b.b3x3	b.b6x5	5.25007	Yes	Yes	9	8	6
286	b.b3x3	b.b7x2	3.74294	Yes	No	9	8	8
287	b.b3x4	b.b4x6	5.71765	No	Yes	4	9	9
288	b.b28x3	b.b3x4	5.23326	Yes	No	4	7	9
289	b.b3x5	b.b6x3	3.478	No	No	0	9	8
290	b.b3x6	b.l3x2	8.61519	No	Yes	0	9	9
291	b.l3x1	b.l5x5	8.14989	Yes	Yes	0	9	9
292	b.b4x2	b.l3x2	7.85594	Yes	Yes	0	8	9
293	b.b4x1	b.l5x1	3.3174	No	Yes	0	8	8
294	b.b4x2	b.b5x8	4.32966	Yes	No	0	8	5
295	b.b4x3	b.b5x7	5.37123	Yes	Yes	0	7	7
296	b.b4x3	b.l5x1	5.73348	Yes	Yes	9	7	8
297	b.b4x3	b.b7x4	5.08596	Yes	No	9	7	8
298	b.b4x4	b.b4x6	13.9715	No	Yes	4	8	9
299	b.b4x4	b.b5x3	4.45504	No	Yes	4	8	9
300	b.b4x5	b.b5x5	8.23405	No	No	0	7	5
301	b.b4x5	b.l8x1	3.78003	No	No	0	7	5
302	b.b4x6	b.b5x3	10.7594	Yes	Yes	4	9	9
303	b.b28x3	b.b4x6	3.3438	Yes	Yes	4	7	9
304	b.b4x7	b.l4x3	8.04174	Yes	No	4	8	6
305	b.l4x1	g.ctx16	5.31655	No	Yes	0	5	8
306	b.l4x2	g.ctx15	11.8308	No	Yes	7	4	9
307	b.l4x2	g.ctx16	7.12828	No	Yes	7	4	8
308	b.b5x2	b.l4x3	8.97744	Yes	No	4	7	6
309	b.b5x4	b.b5x5	6.44276	No	No	0	5	5
310	b.b5x5	b.l8x8	4.87626	No	No	0	5	4
311	b.b5x7	b.b5x8	3.36733	Yes	No	0	7	5
312	b.b5x7	b.b8x4	7.32697	Yes	Yes	0	7	6
313	b.b5x7	b.l8x8	6.73807	Yes	No	0	7	4
314	b.l5x1	b.l5x6	3.80092	Yes	No	0	8	9
315	b.b7x4	b.l5x1	4.13349	No	Yes	9	8	8
316	b.b8x4	b.l5x1	5.02039	Yes	Yes	9	6	8
317	b.b9x3	b.l5x2	5.19866	No	No	0	6	6
318	b.l5x3	b.l7x3	9.8968	No	No	0	8	9
319	b.l5x4	b.l5x5	5.13042	No	Yes	0	8	9
320	b.l5x5	b.l7x2	6.02891	Yes	No	0	9	9
321	b.b6x1	b.l7x1	3.609	Yes	No	0	9	9
322	b.b6x1	b.l9x6	6.34058	Yes	Yes	2	9	8
323	b.b10x3	b.b6x2	6.26829	No	No	0	8	8
324	b.b6x5	b.l6x4	4.69801	Yes	No	0	6	5
325	b.b6x5	b.b7x2	3.1708	Yes	No	9	6	8
326	b.b10x5	b.l6x1	7.11784	Yes	No	0	9	6
327	b.l6x3	b.l6x5	6.64966	No	Yes	13	6	4
328	b.l10x3	b.l6x3	8.97833	No	No	13	6	6
329	b.b7x1	b.l6x5	3.29677	Yes	Yes	13	4	4
330	b.l6x5	b.l8x2	7.56932	Yes	No	0	4	4
331	b.l10x3	b.l6x5	3.2107	No	Yes	13	6	4
332	b.b7x1	b.b8x3	3.52225	Yes	No	0	4	6
333	b.b7x1	b.b8x5	10.9824	Yes	No	0	4	4
334	b.b7x1	b.l10x3	6.97255	Yes	No	13	4	6
335	b.b7x2	b.l8x1	4.98653	No	No	0	8	5
336	b.b10x5	b.b7x3	3.43588	Yes	No	0	9	9
337	b.b7x4	b.b8x4	3.7943	No	Yes	9	8	6
338	b.l7x3	b.l7x5	5.19667	No	No	0	9	6
339	b.l7x4	b.l9x5	3.85731	No	No	0	9	8
340	b.b9x3	b.l7x5	4.79751	No	No	0	6	6
341	b.b8x1	b.b9x4	4.62978	No	No	0	8	9
342	b.b8x2	b.b8x4	5.57431	No	Yes	0	8	6
343	b.b8x2	b.b9x3	3.40412	No	No	0	8	6
344	b.b10x5	b.b8x3	3.39175	Yes	No	0	9	6
345	b.b8x3	b.l12x1	4.79481	No	No	0	6	6
346	b.b8x4	b.l8x10	6.245	Yes	No	0	6	4
347	b.b8x5	b.l8x3	3.6062	No	No	0	4	3
348	b.l8x5	b.l8x7	5.67703	No	No	0	3	3
349	b.l8x7	b.l8x9	4.71145	No	No	0	3	3
350	b.b13x1	b.b9x2	3.22469	No	No	0	4	5
351	b.b12x6	b.b9x4	18.4112	Yes	No	0	8	9
352	b.l9x3	b.l9x7	3.9407	Yes	No	2	9	7
353	b.b11x4	b.l9x3	6.09869	No	Yes	2	9	9
354	b.b11x6	b.l9x3	14.7122	No	Yes	2	9	9
355	b.l11x2	b.l9x3	6.16609	Yes	Yes	2	9	9
356	b.b12x4	b.l9x3	3.3833	No	Yes	2	4	9
357	b.b12x6	b.l9x3	5.36052	Yes	Yes	2	8	9
358	b.l11x2	b.l9x4	7.70317	Yes	No	0	9	5
359	b.b10x1	b.l9x6	3.25464	No	Yes	0	9	8
360	b.l11x1	b.l9x6	7.32789	No	Yes	2	9	8
361	b.l13x6	b.l9x6	9.16789	Yes	Yes	2	9	8
362	b.b14x1	b.l9x6	4.00956	No	Yes	2	8	8
363	b.b11x4	b.l9x7	3.93702	No	No	2	9	7
364	b.b10x1	b.b11x5	3.18238	No	No	0	9	6
365	b.b10x2	b.b14x3	4.58628	No	Yes	0	6	5
366	b.b10x4	b.b14x5	3.28937	No	No	0	6	5
367	b.b10x5	b.b11x2	8.74682	Yes	No	0	9	7
368	b.b11x1	b.l10x1	6.79769	No	No	0	5	3
369	b.b14x5	b.l10x1	4.99213	No	No	0	5	3
370	b.b11x1	b.l10x2	6.48355	No	No	0	5	5
371	b.b12x7	b.l10x4	5.80127	No	No	0	9	3
372	b.l10x4	b.l12x2	5.27603	No	No	0	3	6
373	b.b11x1	b.b12x5	5.91574	No	Yes	0	5	6
374	b.b11x2	b.l12x1	4.00831	No	No	0	7	6
375	b.b11x3	b.b14x3	3.64269	No	Yes	6	5	5
376	b.b11x3	b.b15x1	5.4293	No	Yes	6	5	9
377	b.b11x4	b.b12x6	8.84209	No	Yes	2	9	8
378	b.b11x5	b.l13x7	5.36559	No	No	0	6	9
379	b.b11x5	b.b14x3	4.07585	No	Yes	0	6	5
380	b.b11x6	b.l11x1	3.60781	No	No	2	9	9
381	b.b11x6	b.l11x2	8.25048	No	Yes	2	9	9
382	b.l11x1	b.l13x6	4.26354	No	Yes	2	9	9
383	b.b12x2	b.l11x2	8.76851	No	Yes	0	7	9
384	b.b12x2	b.l13x1	3.10785	No	No	0	7	2
385	b.b12x3	b.b13x7	4.03173	No	Yes	0	8	7
386	b.b12x3	b.l13x7	3.62409	No	No	0	8	9
387	b.b12x4	b.b12x6	4.46784	No	Yes	2	4	8
388	b.b12x4	b.b13x3	5.67956	No	No	2	4	4
389	b.b12x5	b.b13x4	3.76237	Yes	No	0	6	4
390	b.b12x5	b.b13x5	5.03867	Yes	No	0	6	4
391	b.b12x6	b.b13x3	14.2723	Yes	No	2	8	4
392	b.b12x7	b.l12x3	9.03609	No	No	0	9	5
393	b.b13x2	b.l12x3	5.1698	No	No	0	4	5
394	b.b13x3	b.b13x6	5.53392	No	No	0	4	4
395	b.b13x5	b.b13x7	6.10823	No	Yes	0	4	7
396	b.b13x7	b.b15x1	11.1647	Yes	Yes	6	7	9
397	b.b13x7	b.b16x6	14.8007	Yes	Yes	6	7	8
398	b.b13x7	b.b17x1	3.8415	Yes	No	0	7	4
399	b.l13x3	b.l13x7	6.6372	Yes	No	0	9	9
400	b.b15x3	b.l13x3	6.52274	No	Yes	6	9	9
401	b.b15x5	b.l13x3	8.2643	No	Yes	6	8	9
402	b.l13x3	b.l15x2	6.39709	Yes	Yes	6	9	9
403	b.b16x4	b.l13x3	14.8853	Yes	Yes	6	6	9
404	b.b16x6	b.l13x3	3.79846	Yes	Yes	6	8	9
405	b.l13x4	b.l15x2	7.39709	No	Yes	0	3	9
406	b.l13x6	b.l15x1	4.68957	Yes	Yes	2	9	7
407	b.b14x1	b.l15x1	3.0888	No	Yes	2	8	7
408	b.b14x2	b.b18x3	4.34185	No	Yes	0	7	8
409	b.b14x3	b.b15x1	3.6413	Yes	Yes	6	5	9
410	b.b14x4	b.b18x5	6.31803	No	No	0	8	5
411	b.b18x5	b.l14x1	4.68072	No	No	0	5	4
412	b.l14x2	b.l18x4	3.33403	No	No	0	4	7
413	b.l14x3	b.l14x5	7.41471	No	No	0	5	5
414	b.l14x5	b.l16x2	9.26159	No	No	0	5	9
415	b.b16x5	b.l14x6	5.30451	No	No	0	5	3
416	b.b16x7	b.l14x6	3.9876	No	No	0	9	3
417	b.b15x1	b.b16x6	12.8292	Yes	Yes	6	9	8
418	b.b15x2	b.b18x3	6.66302	No	Yes	5	6	8
419	b.b15x2	b.b18x5	9.10078	No	No	0	6	5
420	b.b15x2	b.b19x2	10.1449	No	Yes	5	6	6
421	b.b15x3	b.b16x6	6.77256	No	Yes	6	9	8
422	b.b15x4	b.l17x7	3.39337	No	No	0	6	7
423	b.b15x5	b.l15x2	3.7168	No	Yes	6	8	9
424	b.l15x1	b.l17x6	9.99327	Yes	Yes	2	7	9
425	b.b16x2	b.l15x2	8.3731	No	Yes	0	5	9
426	b.b16x4	b.b16x6	8.42602	Yes	Yes	6	6	8
427	b.b16x4	b.b17x3	6.03602	Yes	No	6	6	5
428	b.b16x4	b.b17x6	11.806	Yes	No	0	6	7
429	b.b16x5	b.b17x5	5.2672	No	Yes	0	5	7
430	b.b16x5	b.l20x1	5.36276	No	No	0	5	6
431	b.b16x6	b.b17x3	7.25173	Yes	No	6	8	5
432	b.b16x7	b.l16x3	11.1775	No	No	0	9	3
433	b.b16x7	b.b17x4	11.6832	No	No	0	9	5
434	b.b17x2	b.l16x3	4.83946	No	No	0	3	3
435	b.b17x2	b.b17x4	3.94682	No	No	0	3	5
436	b.b17x3	g.h1x10	5.70705	No	No	0	5	9
437	b.b17x5	b.b17x7	8.62733	Yes	Yes	5	7	8
438	b.b17x5	b.b21x1	10.3321	Yes	Yes	5	7	7
439	b.b17x5	g.l1x2	4.1755	Yes	No	5	7	2
440	b.b17x6	g.h1x14	8.55128	No	No	0	7	9
441	b.b17x7	b.b19x2	10.5149	Yes	Yes	5	8	6
442	b.b17x7	b.b20x6	9.43682	Yes	Yes	5	8	6
443	b.b17x7	b.b21x1	4.13746	Yes	Yes	5	8	7
444	b.l17x3	b.l17x7	7.45362	Yes	No	5	9	7
445	b.b19x4	b.l17x3	8.78945	Yes	Yes	5	8	9
446	b.b19x6	b.l17x3	12.5949	No	Yes	5	9	9
447	b.l17x3	b.l19x2	7.2132	Yes	Yes	5	9	9
448	b.b20x4	b.l17x3	18.6412	Yes	Yes	5	8	9
449	b.l17x4	b.l19x2	7.557	No	Yes	0	3	9
450	b.l17x5	b.l17x6	4.69357	No	Yes	2	6	9
451	b.l17x5	b.l19x1	4.79611	No	Yes	2	6	9
452	b.l17x6	b.l19x1	5.36	Yes	Yes	2	9	9
453	b.b19x4	b.l17x7	4.60343	Yes	No	5	8	7
454	b.b18x1	b.l19x1	12.5503	No	Yes	2	9	9
455	b.b18x2	b.b22x3	3.13906	No	No	0	5	6
456	b.b18x3	b.b19x2	5.04472	Yes	Yes	5	8	6
457	b.b18x3	b.b19x4	4.61139	Yes	Yes	5	8	8
458	b.l18x1	b.l18x2	10.684	Yes	Yes	11	6	7
459	b.l18x1	b.l18x3	8.20012	Yes	Yes	11	6	5
460	b.b22x5	b.l18x1	9.92006	No	Yes	11	7	6
461	b.l18x1	b.l22x4	4.75459	Yes	No	11	6	9
462	b.l18x1	g.h2x8	5.39942	Yes	No	0	6	7
463	b.l18x1	g.h2x11	4.2877	Yes	Yes	11	6	6
464	b.b22x5	b.l18x2	4.11079	No	Yes	11	7	7
465	b.l18x2	b.l22x4	3.82993	Yes	No	11	7	9
466	b.l18x2	g.h2x11	5.31	Yes	Yes	11	7	6
467	b.l18x3	b.l18x5	10.0355	Yes	No	0	5	2
468	b.l18x3	g.h2x11	9.01056	Yes	Yes	11	5	6
469	b.l18x5	b.l20x2	10.4444	No	No	0	2	9
470	b.b19x2	b.b20x6	10.5531	Yes	Yes	5	6	6
471	b.b19x2	b.l20x1	3.27563	Yes	No	0	6	6
472	b.b19x4	b.b20x6	7.27429	Yes	Yes	5	8	6
473	b.b19x5	b.l21x9	4.41587	No	No	0	5	6
474	b.b19x6	b.l19x2	9.01981	No	Yes	5	9	9
475	b.b20x2	b.l19x2	10.6479	Yes	Yes	5	6	9
476	b.b20x2	b.b20x4	8.40237	Yes	Yes	5	6	8
477	b.b20x2	b.b21x6	3.51157	Yes	No	5	6	1
478	b.b20x2	b.l21x1	4.6706	Yes	No	0	6	2
479	b.b20x3	b.b21x7	4.12492	No	Yes	0	8	5
480	b.b20x3	b.l21x9	5.19527	No	No	0	8	6
481	b.b20x4	b.b20x6	4.31904	Yes	Yes	5	8	6
482	b.b20x4	b.b21x3	15.9055	Yes	Yes	5	8	6
483	b.b20x4	b.b21x6	10.9446	Yes	No	5	8	1
484	b.b20x5	b.b21x7	5.62636	No	Yes	0	7	5
485	b.b20x6	b.b21x3	5.53268	Yes	Yes	5	6	6
486	b.b20x7	b.l20x3	3.99643	No	No	0	9	7
487	b.b20x7	b.b21x4	6.85168	No	No	0	9	5
488	b.b20x7	g.h2x4	4.61195	No	No	0	9	7
489	b.l20x2	g.l1x5	8.45783	No	No	0	9	4
490	b.l20x2	g.h2x7	8.07105	No	No	0	9	5
491	b.b21x1	g.l1x2	4.42067	Yes	No	5	7	2
492	b.b21x1	g.l1x4	10.2592	Yes	Yes	5	7	8
493	b.b21x2	g.h2x1	4.08006	No	No	0	6	8
494	b.b21x3	b.b21x6	5.3055	Yes	No	5	6	1
495	b.b21x5	b.b21x7	10.7294	Yes	Yes	0	4	5
496	b.b21x5	b.b25x1	3.9261	Yes	No	0	4	2
497	b.b21x7	b.b23x2	4.28094	Yes	No	0	5	6
498	b.b21x7	b.b24x6	9.74269	Yes	Yes	0	5	8
499	b.l21x2	b.l21x4	9.62883	Yes	No	0	4	4
500	b.l21x2	b.l21x5	4.33607	Yes	No	0	4	4
501	b.b23x6	b.l21x5	6.32169	Yes	No	0	7	4
502	b.b23x6	b.l21x7	3.16511	Yes	Yes	2	7	5
503	b.l21x7	b.l23x1	3.22315	Yes	Yes	2	5	6
504	b.l21x7	b.l23x2	7.3149	Yes	No	2	5	8
505	b.b23x6	b.l21x9	10.2267	Yes	No	0	7	6
506	b.b22x1	b.b22x2	3.37905	No	No	0	8	8
507	b.b22x1	b.l25x6	7.00068	No	Yes	0	8	8
508	b.b22x2	b.b26x3	4.94135	No	No	0	8	6
509	b.b22x4	b.b26x5	4.54161	No	No	0	5	7
510	b.b22x5	b.b23x2	9.3883	No	No	0	7	6
511	b.b23x1	b.l22x1	3.80908	Yes	No	0	5	9
512	b.l22x1	g.ctx3	8.50715	No	Yes	0	9	9
513	b.l22x1	g.ctx5	3.19782	No	No	0	9	9
514	b.l22x3	g.ctx3	8.27476	No	Yes	0	9	9
515	b.b24x7	b.l22x5	12.3263	No	Yes	12	9	9
516	b.l22x5	b.l24x2	8.91687	Yes	No	0	9	6
517	b.l22x5	g.ctx6	4.9544	Yes	Yes	12	9	6
518	b.b23x1	b.b24x5	5.57189	Yes	No	0	5	5
519	b.b23x1	g.ctx6	3.13979	Yes	Yes	0	5	6
520	b.b23x3	b.b24x5	4.54237	No	No	0	7	5
521	b.b23x3	b.b27x1	4.68853	No	No	0	7	6
522	b.b23x4	b.b23x6	4.83106	No	Yes	0	6	7
523	b.b23x5	b.b24x3	3.08933	No	No	0	7	5
524	b.b23x6	b.l23x2	3.9686	Yes	No	2	7	8
525	b.b23x6	b.b24x4	12.7399	Yes	Yes	2	7	6
526	b.b23x6	b.b24x6	6.8949	Yes	Yes	2	7	8
527	b.l23x1	b.l25x6	11.6352	Yes	Yes	2	6	8
528	b.b24x2	b.l23x2	8.7637	No	No	0	5	8
529	b.b24x1	b.l25x5	3.38014	No	No	0	4	7
530	b.b24x2	b.b25x6	4.18713	No	No	0	5	3
531	b.b24x3	b.b25x7	5.15413	No	Yes	0	5	7
532	b.b24x3	b.l25x7	3.93349	No	No	0	5	7
533	b.b24x4	b.b24x6	4.5722	Yes	Yes	2	6	8
534	b.b24x4	b.b25x3	11.727	Yes	No	2	6	5
535	b.b24x4	b.b25x6	4.04879	Yes	No	0	6	3
536	b.b24x6	b.b25x3	6.48429	Yes	No	2	8	5
537	b.b24x7	b.l24x3	8.75295	No	Yes	0	9	5
538	b.l24x2	g.h2x12	4.57442	No	No	0	6	7
539	b.b25x7	b.b28x6	17.7652	Yes	Yes	0	7	9
540	b.l25x3	b.l25x7	4.19651	Yes	No	0	9	7
541	b.b27x3	b.l25x3	7.77146	No	Yes	0	8	9
542	b.b27x5	b.l25x3	13.1026	No	Yes	10	9	9
543	b.l25x3	b.l28x2	7.45813	Yes	Yes	10	9	9
544	b.b28x4	b.l25x3	11.6877	Yes	Yes	10	6	9
545	b.l25x4	b.l28x2	4.6739	Yes	Yes	0	5	9
546	I1x49	b.l25x4	9.3694	No	Yes	0	7	5
547	8x56	b.l25x4	3.98923	No	Yes	0	7	5
548	b.l25x5	b.l28x1	5.38687	No	Yes	0	7	9
549	b.l25x6	b.l28x1	20.4614	Yes	Yes	2	8	9
550	b.b26x1	b.l28x1	5.89707	No	Yes	0	9	9
551	b.b26x3	b.b27x3	3.63308	No	No	0	6	8
552	b.b26x5	b.b27x1	4.04456	No	No	0	7	6
553	b.l27x1	b.l27x3	6.79968	No	No	4	7	7
554	b.l27x3	b.l27x5	6.86493	No	No	0	7	5
555	b.l27x5	g.ctx4	4.79385	No	No	0	5	7
556	b.l27x5	g.ctx15	5.23438	No	Yes	0	5	9
557	b.l27x6	g.ctx16	4.67686	No	Yes	0	7	8
558	b.b27x3	b.b28x6	7.883	No	Yes	0	8	9
559	b.b27x5	b.l28x2	8.53514	No	Yes	10	9	9
560	b.b28x2	b.l28x2	11.2544	No	Yes	0	4	9
561	b.b28x1	b.b28x2	3.45941	No	No	0	4	4
562	b.b28x4	b.b28x6	6.14358	Yes	Yes	10	6	9
563	b.b28x5	g.ctx16	4.72189	No	Yes	7	5	8
564	b.b28x7	g.ctx14	9.57328	No	Yes	7	9	9
565	b.b28x7	g.ctx16	5.46663	No	Yes	7	9	8
566	g.h1x10	g.h1x14	7.65014	No	No	0	9	9
567	g.l1x2	g.l1x4	8.64755	No	Yes	5	2	8
568	g.h2x3	g.l1x5	3.76616	No	No	0	5	4
569	g.h2x3	g.h2x7	3.89553	No	No	0	5	5
570	g.h2x11	g.h2x15	18.3301	Yes	No	0	6	6
571	g.ctx2	g.h2x15	8.24723	No	No	0	3	6
572	g.ctx3	g.ctx4	4.6391	Yes	No	0	9	7
573	g.ctx3	g.ctx6	6.60666	Yes	Yes	0	9	6
574	g.ctx10	g.ctx9	3.48065	No	No	7	5	6
575	g.ctx14	g.ctx9	3.24034	Yes	No	7	9	6
576	g.ctx14	g.ctx15	6.10396	Yes	Yes	7	9	9
577	g.ctx14	g.ctx16	3.6314	Yes	Yes	7	9	8
578	g.ctx15	g.ctx16	5.35524	Yes	Yes	7	9	8
579	NT	NT	469.014	Yes	Yes	1	4	4
580	Lig	NT	73.1679	Yes	Yes	1	0	4
581	E1	NT	7.55387	Yes	Yes	1	3	4
582	1x29	Lig	8.52252	No	Yes	1	2	0
583	1x31	7x31	7.65034	No	No	0	4	4
584	1x32	Lig	15.9597	No	Yes	1	5	0
585	1x35	7x35	3.25262	No	No	0	6	6
586	1x35	Lig	3.65769	No	Yes	1	6	0
587	1x36	1x39	3.2845	Yes	Yes	1	5	7
588	1x36	2x61	3.73493	Yes	No	1	5	7
589	1x36	Lig	4.79286	Yes	Yes	1	5	0
590	1x39	1x43	3.27249	Yes	Yes	1	7	7
591	1x39	2x57	3.09512	Yes	Yes	1	7	7
592	1x39	2x61	3.18982	Yes	No	1	7	7
593	1x39	7x38	4.23481	Yes	No	1	7	7
594	1x39	7x42	3.27769	Yes	No	1	7	9
595	1x39	Lig	5.25878	Yes	Yes	1	7	0
596	1x42	7x43	6.57814	No	No	0	8	7
597	1x43	2x53	5.96417	Yes	Yes	1	7	8
598	1x43	2x54	4.01758	Yes	No	0	7	7
599	1x43	2x57	12.4621	Yes	Yes	1	7	7
600	1x43	7x42	5.77487	Yes	No	1	7	9
601	1x43	Lig	4.40711	Yes	Yes	1	7	0
602	1x45	7x47	5.45905	No	No	0	5	7
603	1x49	7x47	4.0579	No	No	0	7	7
604	1x50	2x47	5.35595	Yes	No	0	9	8
605	1x50	2x50	3.72987	Yes	Yes	0	9	8
606	1x50	2x51	3.2462	Yes	No	0	9	7
607	1x50	7x50	3.53558	Yes	No	0	9	8
608	1x51	2x51	3.71219	No	No	0	3	7
609	1x52	7x55	3.34405	No	Yes	0	4	8
610	1x53	7x54	3.40677	No	No	0	9	9
611	1x54	2x44	3.511	No	No	0	6	6
612	1x56	7x54	3.62834	No	No	0	8	9
613	1x57	2x40	5.10873	No	No	0	8	9
614	1x57	2x44	5.19324	No	No	0	8	6
615	1x58	2x44	5.00657	No	No	0	3	6
616	1x60	I1x50	3.63489	Yes	No	0	7	9
617	1x60	8x53	7.50983	Yes	No	0	7	8
618	1x60	8x57	3.41027	Yes	No	0	7	5
619	I1x48	I1x51	3.6583	No	No	0	8	7
620	8x53	I1x49	5.41857	No	No	0	8	7
621	8x49	I1x50	5.0584	No	No	0	9	9
622	2x41	I1x51	4.07173	No	No	0	6	7
623	2x37	2x40	3.65982	No	No	0	8	9
624	2x38	3x49	5.36907	Yes	Yes	0	7	8
625	2x38	4x39	3.12613	Yes	No	0	7	6
626	2x38	4x43	3.23262	Yes	No	0	7	6
627	2x39	2x40	7.2678	Yes	No	0	9	9
628	2x39	2x43	3.649	Yes	No	0	9	9
629	2x41	4x43	3.78866	No	No	0	6	6
630	2x42	3x46	5.22236	No	Yes	0	8	9
631	2x42	3x49	4.60227	No	Yes	19	8	8
632	2x42	4x46	3.68365	No	No	19	8	7
633	2x43	3x46	9.52919	No	Yes	0	9	9
634	2x43	7x53	4.88254	No	No	0	9	8
635	2x45	3x42	13.1765	No	Yes	21	9	9
636	2x45	4x47	5.01295	No	No	0	9	5
637	2x45	4x50	4.3617	No	Yes	21	9	9
638	2x46	2x50	7.023	No	Yes	0	9	8
639	2x46	3x46	8.40862	No	Yes	0	9	9
640	2x49	3x39	4.24801	No	No	0	9	9
641	2x49	3x42	3.44628	No	Yes	0	9	9
642	2x50	3x39	13.6701	Yes	No	0	8	9
643	2x50	7x45	6.27448	Yes	Yes	0	8	9
644	2x50	7x46	4.46324	Yes	No	0	8	9
645	2x52	3x35	7.43859	No	Yes	0	7	5
646	2x53	3x36	5.71452	Yes	No	1	8	6
647	2x53	3x39	9.07699	Yes	No	0	8	9
648	2x53	3x40	3.60288	Yes	Yes	1	8	8
649	2x53	Lig	3.35082	Yes	Yes	1	8	0
650	2x56	3x35	4.63747	No	Yes	0	6	5
651	2x57	2x61	3.8926	Yes	No	1	7	7
652	2x57	Lig	3.44571	Yes	Yes	1	7	0
653	2x60	3x32	7.40688	Yes	Yes	1	6	6
654	2x60	Lig	5.77343	Yes	Yes	1	6	0
655	E1	E1	20.115	Yes	Yes	1	3	3
656	E1	Lig	19.4369	Yes	Yes	1	3	0
657	3x25	E1	3.41027	No	Yes	1	9	3
658	E1	E2	4.34483	Yes	Yes	1	3	5
659	E1	E2x50	3.13093	Yes	No	1	3	9
660	3x25	E2x50	6.3336	No	No	1	9	9
661	3x26	E2	6.39606	Yes	Yes	1	8	5
662	3x26	E2x51	18.775	Yes	Yes	1	8	8
663	3x32	3x33	3.15707	Yes	Yes	1	6	7
664	3x32	Lig	8.23129	Yes	Yes	1	6	0
665	3x33	4x60	6.14867	Yes	Yes	1	7	8
666	3x33	5x43	8.25183	Yes	No	1	7	7
667	3x33	Lig	4.7409	Yes	Yes	1	7	0
668	3x34	3x35	3.89958	Yes	Yes	0	9	5
669	3x34	3x38	4.30093	Yes	No	0	9	8
670	3x34	4x54	4.15007	Yes	No	0	9	3
671	3x34	4x57	3.87476	Yes	No	0	9	6
672	3x36	3x40	4.88869	No	Yes	1	6	8
673	3x36	Lig	6.97232	No	Yes	1	6	0
674	3x37	4x53	3.20342	No	No	0	6	9
675	3x38	4x50	4.6903	No	Yes	0	8	9
676	3x38	4x53	3.77773	No	No	0	8	9
677	3x40	5x47	10.2203	Yes	No	1	8	7
678	3x40	5x51	3.41995	Yes	No	1	8	7
679	3x40	6x48	11.4541	Yes	Yes	1	8	8
680	3x40	Lig	3.09523	Yes	Yes	1	8	0
681	3x41	4x52	4.60578	No	No	0	6	3
682	3x42	3x45	4.69025	Yes	No	0	9	8
683	3x42	4x491	6.46795	Yes	No	0	9	9
684	3x42	4x50	15.3646	Yes	Yes	21	9	9
685	3x43	7x45	3.3032	No	Yes	0	9	9
686	3x44	3x48	3.25177	Yes	No	0	8	6
687	3x44	5x50	4.56596	Yes	No	0	8	7
688	3x44	5x53	3.62183	Yes	No	0	8	6
689	3x44	5x54	4.27407	Yes	No	0	8	9
690	3x46	6x43	7.44348	Yes	No	0	9	9
691	3x49	3x53	7.66392	Yes	No	0	8	8
692	3x49	4x46	4.09456	Yes	No	19	8	7
693	3x50	5x61	4.57348	No	No	0	9	9
694	3x51	5x57	11.4852	No	No	0	8	8
695	3x51	5x60	6.41566	No	No	0	8	8
696	3x52	I2	4.07822	No	Yes	3	7	7
697	4x42	I2	5.37091	No	Yes	3	5	7
698	4x43	4x47	3.1969	No	No	0	6	5
699	4x56	5x46	9.54955	No	No	0	5	8
700	4x60	4x64	8.46624	Yes	Yes	1	8	8
701	4x60	E2x51	3.1869	Yes	Yes	1	8	8
702	4x60	5x421	3.26796	Yes	No	0	8	8
703	4x60	5x43	9.21472	Yes	No	1	8	7
704	4x64	4x68	6.20673	Yes	No	1	8	6
705	4x64	E2x51	16.0729	Yes	Yes	1	8	8
706	4x66	4x67	3.49935	No	No	0	3	3
707	4x68	E2	11.898	No	Yes	1	6	5
708	E2	E2x51	5.49143	Yes	Yes	1	5	8
709	E2	E2	14.5475	Yes	Yes	1	5	5
710	E2x52	Lig	13.3905	No	Yes	1	5	0
711	E2	Lig	18.2261	Yes	Yes	1	5	0
712	5x41	E2	7.86826	No	Yes	1	6	5
713	5x41	5x44	6.04431	No	Yes	1	6	6
714	5x41	Lig	5.31622	No	Yes	1	6	0
715	5x42	5x44	5.87107	No	Yes	1	7	6
716	5x45	5x46	3.23297	No	No	0	4	8
717	5x47	Lig	3.30043	No	Yes	1	7	0
718	5x51	6x48	3.49101	No	Yes	1	7	8
719	5x55	5x59	3.40151	No	No	0	6	5
720	5x55	6x49	8.00276	No	No	0	6	6
721	5x58	5x62	4.66877	Yes	No	0	9	7
722	5x58	6x40	3.90134	Yes	No	20	9	9
723	5x58	6x44	4.69463	Yes	Yes	20	9	9
724	5x58	6x46	6.80019	Yes	No	0	9	7
725	5x62	6x37	4.0253	No	No	0	7	9
726	5x69	6x32	4.14449	No	No	0	8	8
727	6x39	7x52	7.04588	No	No	0	8	8
728	6x40	6x44	3.46093	No	Yes	20	9	9
729	6x41	6x46	5.35997	No	No	0	8	7
730	6x42	7x48	4.0959	No	No	0	9	5
731	6x43	6x44	3.11326	No	Yes	0	9	9
732	6x43	7x53	15.4617	No	No	0	9	8
733	6x47	6x48	9.32998	No	Yes	1	8	8
734	6x47	7x40	6.50709	No	No	0	8	6
735	6x47	7x45	7.14788	No	Yes	1	8	9
736	6x48	7x41	6.28515	Yes	No	1	8	6
737	6x50	6x51	3.45507	No	Yes	1	6	7
738	6x51	7x33	6.62012	Yes	Yes	1	7	7
739	6x51	7x36	4.01613	Yes	No	1	7	4
740	6x51	7x37	4.06716	Yes	Yes	1	7	8
741	E3	E3	7.57468	Yes	Yes	1	4	4
742	7x30	E3	5.08525	No	Yes	1	5	4
743	E3	Lig	8.64252	Yes	Yes	1	4	0
744	7x33	E3	3.31011	Yes	Yes	1	7	4
745	7x30	7x34	3.83779	No	No	1	5	5
746	7x30	Lig	5.01395	No	Yes	1	5	0
747	7x33	7x37	6.33462	Yes	Yes	1	7	8
748	7x34	Lig	6.80306	No	Yes	1	5	0
749	7x37	Lig	6.34371	Yes	Yes	1	8	0
750	7x38	Lig	8.82829	No	Yes	1	7	0
751	7x41	Lig	3.92269	No	Yes	1	6	0
752	7x42	7x43	3.2559	No	No	0	9	7
753	7x47	7x51	5.18975	No	No	0	7	6
754	7x51	7x55	3.51331	No	Yes	0	6	8
755	7x52	7x53	6.87555	No	No	0	8	8
756	7x54	7x55	3.63311	No	Yes	0	9	8
757	8x47	8x49	3.7284	No	No	0	9	9
758	8x47	8x50	6.20425	No	No	0	9	9
759	8x58	8x62	3.57434	Yes	No	0	5	4
760	Lig	Lig	85.7267	Yes	Yes	1	0	0
761	G.HN.46	G.HN.49	3.46834	No	No	0	4	4
762	G.H5.04	G.S2.06	3.55915	No	No	0	8	9
763	G.S3.01	I2	8.39617	No	Yes	3	5	7
764	G.H2.03	b.l13x6	3.95538	No	Yes	2	9	9
765	G.H5.15	I2	4.02144	No	Yes	3	8	7
766	b.lhb1x10	b.lhb1x8	5.09742	No	No	0	4	2
767	b.b10x2	b.b10x4	4.28018	No	No	0	6	6
768	g.ctx13	g.ctx9	3.54994	No	No	7	5	6
769	1x47	2x54	3.11507	No	No	0	7	7
770	2x57	3x32	3.4028	Yes	Yes	1	7	6
771	3x26	E1	3.8615	Yes	Yes	1	8	3
772	3x41	4x53	5.78786	No	No	0	6	9
773	3x51	3x55	10.7475	No	No	0	8	6
774	5x44	Lig	8.87703	Yes	Yes	1	6	0
775	5x54	6x44	6.11095	No	Yes	0	9	9
776	7x36	7x40	4.51963	No	No	0	4	6
777	G.HN.34	G.HN.37	3.33597	No	No	0	4	3
778	G.S1.02	I2	5.55643	Yes	Yes	3	6	7
779	G.H3.13	G.h4s6.08	3.12063	Yes	No	0	6	5
780	G.H5.08	I2	4.91856	Yes	Yes	3	8	7
781	G.H5.12	I2	7.32053	No	Yes	3	7	7
782	G.H5.17	I3	5.23585	Yes	Yes	3	5	5
783	b.b1x3	g.ctx17	3.59163	Yes	No	0	7	7
784	b.b25x3	b.l21x2	6.87143	No	Yes	0	5	4
785	g.ctx10	g.ctx13	6.09114	No	No	7	5	5
786	1x28	Lig	3.51938	No	Yes	1	0	0
787	1x33	Lig	3.25678	No	Yes	0	3	0
788	3x29	3x33	3.37938	No	Yes	0	5	7
789	3x56	I2	3.68512	No	Yes	3	5	7
790	I2	I2	6.75213	Yes	Yes	3	7	7
791	4x64	5x40	3.6485	Yes	Yes	1	8	4
792	5x60	5x63	4.67918	No	No	0	8	7
793	I3	I3	5.67635	Yes	Yes	3	5	5
794	6x48	7x45	4.79431	Yes	Yes	1	8	9
795	6x50	7x36	3.47893	No	No	1	6	4
796	7x29	E3	4.33296	No	Yes	0	3	4
797	7x33	Lig	3.24184	Yes	Yes	1	7	0
798	b.1x2	b.1x5	3.75617	No	No	0	1	3
799	5x40	E2	4.85156	Yes	Yes	1	4	5
800	1x31	1x32	4.50331	No	No	0	4	5
801	2x65	Lig	3.88179	No	Yes	0	4	0
802	1x25	NT	6.35883	No	Yes	1	0	4
803	7x39	7x43	3.78493	No	No	0	5	7
804	4x44	4x45	3.66908	No	No	0	4	2
805	5x42	E2	3.2166	No	Yes	1	7	5
806	1x24	NT	4.4713	No	Yes	1	0	4
807	E1	E2x52	3.3345	Yes	No	1	3	5
808	G.H5.16	I2	3.5608	No	Yes	3	6	7
809	5x43	5x44	3.23724	No	Yes	1	7	6
810	1x28	NT	3.3268	No	Yes	1	0	4
811	6x35	6x39	3.0767	No	No	0	8	8
812	1x46	7x46	3.05527	No	No	0	9	9
813	b.l22x2	g.ctx3	3.04638	No	Yes	0	1	9
814	b.l22x2	b.l27x4	3.04508	No	No	0	1	9
815	b.1x4	g.h1x5	3.03861	Yes	Yes	0	8	6
816	6x29	I3	3.0347	No	Yes	3	5	5
817	G.HN.29	G.HN.30	3.02361	No	No	0	2	4
818	G.H3.05	G.S4.06	3.02279	No	No	0	9	7
819	b.h2x1	g.h2x5	3.01737	Yes	No	0	5	6
820	1x34	7x35	3.01587	No	No	0	4	6
821	3x47	6x44	3.01204	No	Yes	0	8	9
822	G.HN.28	G.HN.30	3.00127	No	No	0	2	4
823	b.h2x2	b.lh12x4	2.98667	No	No	0	1	3
824	3x54	5x64	2.96902	No	No	0	8	9
825	5x65	G.H5.20	2.96253	No	Yes	0	8	8
826	b.b10x2	b.b6x2	2.94865	No	No	0	6	8
827	b.l24x3	b.lhb1x5	2.93862	Yes	No	0	5	1
828	G.S5.07	G.s5hg.01	2.92125	Yes	No	0	9	9
829	b.b7x5	b.l9x7	2.9184	No	No	0	9	7
830	b.b19x3	b.b23x2	2.91681	No	No	0	4	6
831	2x60	2x64	2.91368	Yes	No	0	6	7
832	3x30	E2x51	2.91181	No	Yes	0	5	8
833	G.S1.06	G.S4.03	2.91012	No	No	0	8	7
834	4x65	E2x51	2.90841	No	Yes	0	3	8
835	8x58	8x59	2.908	Yes	No	0	5	4
836	g.h1x1	g.h1x5	2.9076	Yes	Yes	0	2	6
837	3x48	5x57	2.90103	No	No	0	6	8
838	1x36	1x40	2.87985	Yes	No	0	5	7
839	b.h2x5	g.h2x9	2.8745	Yes	No	0	5	4
840	b.1x6	b.1x9	2.87133	No	No	0	3	4
841	5x51	6x49	2.84693	No	No	0	7	6
842	6x54	E3	2.8457	No	Yes	1	5	4
843	b.b25x5	b.lhb1x8	2.79314	No	No	0	4	2
844	6x41	6x42	2.77838	No	No	0	8	9
845	b.b24x2	b.l25x1	2.77444	No	No	0	5	3
846	g.h1x12	g.h1x8	2.77073	Yes	No	0	6	7
847	G.h4s6.11	G.h4s6.20	2.76895	No	Yes	0	2	4
848	b.h2x4	g.h2x5	2.7634	No	No	0	3	6
849	1x59	1x60	2.73412	No	Yes	0	1	7
850	b.l10x1	b.l14x4	2.72584	No	No	0	3	1
851	b.l14x1	b.l14x3	2.71868	No	No	0	4	5
852	b.b26x4	b.b2x5	2.71667	No	Yes	0	5	7
853	b.b21x5	b.h2x2	2.70144	Yes	No	0	4	1
854	b.b10x5	b.b6x4	2.69377	Yes	No	0	9	7
855	G.S2.02	G.s3h2.01	2.68997	Yes	No	0	5	9
856	G.S4.05	G.s1h1.05	2.66528	No	No	0	7	9
857	b.l16x1	b.l16x2	2.66373	No	No	0	4	9
858	3x22	3x24	2.6588	No	No	0	0	3
859	6x32	6x35	2.64333	No	No	0	8	8
860	b.b25x2	b.l24x3	2.63517	No	Yes	0	2	5
861	b.b10x3	b.b11x2	2.62973	No	No	0	8	7
862	b.b16x3	b.b19x2	2.6224	No	Yes	0	6	6
863	b.1x1	b.1x5	2.62181	Yes	No	0	4	3
864	G.S2.02	G.hfs2.06	2.61344	Yes	No	0	5	7
865	2x50	7x49	2.613	Yes	No	0	8	9
866	b.1x12	g.h1x11	2.57291	No	No	0	6	9
867	b.l7x5	b.l9x1	2.56816	No	No	0	6	5
868	b.l27x2	b.l2x2	2.56427	No	No	0	1	1
869	b.b24x5	b.b25x5	2.5611	No	No	0	5	4
870	3x30	4x61	2.55625	No	No	0	5	5
871	b.b10x5	b.l6x2	2.5545	Yes	No	0	9	6
872	6x52	Lig	2.55427	No	Yes	0	6	0
873	G.HG.04	G.s4h3.01	2.54113	No	No	0	8	6
874	b.lhb1x4	b.lhb1x5	2.53767	No	No	0	1	1
875	b.b19x1	g.h2x8	2.53744	No	No	0	6	7
876	3x31	3x35	2.53178	No	Yes	0	5	5
877	1x53	2x47	2.53108	No	No	0	9	8
878	G.HG.09	G.hgh4.21	2.5127	No	Yes	0	2	4
879	4x49	4x52	2.5025	No	No	0	6	3
880	b.b5x3	b.l1x2	2.49255	Yes	No	0	9	9
881	g.ctx12	g.ctx13	2.48176	No	No	0	6	5
882	b.1x15	g.h1x15	2.44767	No	No	0	7	8
883	b.b12x5	b.l16x1	2.41238	Yes	No	0	6	4
884	4x63	5x40	2.3907	No	Yes	0	4	4
885	g.ctx7	g.ctx8	2.38417	No	No	0	4	8
886	3x41	4x56	2.3829	No	No	0	6	5
887	b.1x22	g.l1x4	2.36381	No	Yes	0	3	8
888	1x60	8x54	2.36181	Yes	No	0	7	5
889	4x42	G.HN.52	2.336	No	No	0	5	3
890	b.l21x8	b.l23x1	2.32976	No	Yes	0	4	6
891	G.HN.38	G.HN.41	2.32907	Yes	No	0	2	4
892	6x36	G.H5.25	2.32508	No	No	0	9	8
893	b.b28x6	b.l25x2	2.32314	Yes	No	0	9	5
894	1x21	NT	2.31829	No	Yes	0	0	4
895	G.H1.04	G.S5.07	2.31	No	Yes	0	7	9
896	8x56	8x60	2.28952	No	No	0	7	7
897	8x58	8x61	2.2831	Yes	No	0	5	4
898	2x68	Lig	2.27688	No	Yes	0	3	0
899	G.hgh4.11	G.hgh4.13	2.27623	Yes	No	0	5	4
900	1x40	2x58	2.27551	No	No	0	7	7
901	G.HN.41	G.HN.45	2.2707	No	No	0	4	4
902	2x48	4x50	2.26353	No	Yes	0	3	9
903	8x48	G.H5.24	2.24282	No	No	0	6	6
904	b.1x4	g.h1x4	2.2245	Yes	No	0	8	5
905	G.H4.11	G.s4h3.01	2.17685	No	No	0	8	6
906	G.HG.03	G.s4h3.02	2.17621	No	No	0	6	9
907	1x44	2x58	2.17616	No	No	0	6	7
908	g.h2x13	g.h2x9	2.1481	No	No	0	1	4
909	G.HN.28	G.HN.31	2.13567	No	No	0	2	3
910	6x53	Lig	2.1311	No	Yes	0	4	0
911	G.H4.03	G.HG.05	2.12775	Yes	No	0	4	4
912	G.H1.01	G.H1.02	2.12643	No	No	0	9	9
913	g.ctx11	g.ctx17	2.10981	No	No	0	4	7
914	5x48	Lig	2.10334	No	Yes	0	4	0
915	b.b7x1	b.b9x1	2.09369	Yes	No	0	4	4
916	G.HG.14	G.HG.17	2.08316	No	No	0	6	3
917	g.h2x14	g.h2x15	2.0805	No	No	0	4	6
918	G.HN.29	G.HN.32	2.07355	No	No	0	2	6
919	G.H1.09	G.S2.04	2.06705	No	No	0	8	7
920	G.S2.02	G.S3.07	2.05971	Yes	Yes	0	5	9
921	b.l18x3	b.l18x4	2.05578	Yes	No	0	5	7
922	b.b2x2	b.b6x3	2.05314	No	No	0	7	8
923	G.H5.21	G.h4s6.20	2.05093	No	Yes	0	4	4
924	G.HG.02	G.s6h5.02	2.04626	No	No	0	9	8
925	3x43	6x45	2.0452	No	No	0	9	9
926	g.ctx1	g.ctx2	2.03271	No	No	0	1	3
927	b.1x10	b.1x6	2.02403	No	No	0	1	3
928	b.b25x4	b.lhb1x9	2.00734	No	No	0	4	3
929	G.hgh4.04	G.hgh4.07	1.99637	Yes	No	0	6	2
930	b.b27x4	b.b28x3	1.99011	No	Yes	0	5	7
931	G.S4.07	G.s5hg.01	1.986	No	No	0	8	9
932	4x54	4x58	1.98487	No	No	0	3	3
933	b.b13x1	b.l12x3	1.9656	No	No	0	4	5
934	b.b16x6	b.l13x2	1.9469	Yes	No	0	8	6
935	5x67	I3	1.94497	No	Yes	0	7	5
936	b.b12x6	b.l9x2	1.93517	Yes	No	0	8	5
937	G.hgh4.15	G.hgh4.16	1.93417	No	No	0	2	1
938	G.H1.08	G.H5.04	1.9283	No	No	0	9	8
939	b.1x13	b.1x9	1.92587	No	No	0	1	4
940	b.l8x3	b.l8x5	1.92436	No	No	0	3	3
941	G.H4.06	G.hgh4.05	1.89671	No	Yes	0	8	6
942	b.b18x4	b.b22x3	1.89319	No	No	0	3	6
943	8x51	8x55	1.88786	No	No	0	7	6
944	5x66	6x33	1.881	No	No	0	6	9
945	G.HG.07	G.s4h3.04	1.87716	No	No	0	9	8
946	b.b17x2	g.h1x13	1.87284	No	No	0	3	1
947	b.1x11	g.h1x12	1.8706	No	Yes	0	8	6
948	g.h1x11	g.h1x7	1.8644	No	No	0	9	2
949	7x28	E3	1.8642	No	Yes	0	2	4
950	b.b9x2	b.l12x1	1.85578	No	No	0	5	6
951	4x42	4x45	1.83917	No	No	0	5	2
952	b.1x14	g.h1x15	1.83243	No	No	0	4	8
953	b.h2x3	b.lh12x3	1.81172	No	No	0	1	4
954	G.S5.07	G.s6h5.03	1.8109	Yes	No	0	9	9
955	G.hgh4.03	G.hgh4.04	1.80859	No	Yes	0	6	6
956	b.b12x1	b.l13x5	1.8018	No	No	0	6	5
957	3x24	E1	1.794	No	Yes	1	3	3
958	g.h1x12	g.h1x9	1.78457	Yes	No	0	6	6
959	G.H3.01	G.s4h3.13	1.77853	Yes	No	0	9	4
960	6x33	6x37	1.77141	No	No	0	9	9
961	G.HG.15	G.s4h3.04	1.77044	No	No	0	7	8
962	G.h4s6.09	G.h4s6.10	1.76958	No	No	0	4	3
963	3x52	4x41	1.768	No	No	0	7	5
964	G.S2.07	G.s2s3.02	1.75479	No	No	0	3	4
965	4x67	5x40	1.72924	No	Yes	0	3	4
966	b.l2x2	b.l6x2	1.72667	No	No	0	1	6
967	5x56	5x60	1.72523	No	No	0	5	8
968	b.1x11	b.1x14	1.7214	No	No	0	8	4
969	b.l8x3	b.l8x6	1.71687	No	No	0	3	4
970	4x38	4x41	1.70413	No	No	0	7	5
971	7x51	7x56	1.69788	No	No	0	6	6
972	8x55	8x58	1.69253	No	Yes	0	6	5
973	1x38	7x39	1.673	No	No	0	6	5
974	G.HN.30	G.HN.34	1.65611	No	No	0	4	4
975	b.b21x7	b.l24x1	1.64812	Yes	No	0	5	5
976	5x37	5x40	1.64621	No	Yes	0	5	4
977	5x38	5x40	1.6361	No	Yes	0	5	4
978	G.H4.03	G.HG.08	1.62715	Yes	No	0	4	7
979	G.H1.01	G.s1h1.01	1.62507	No	No	0	9	9
980	5x39	5x42	1.60876	No	No	0	3	7
981	b.b19x5	b.b22x3	1.59467	No	No	0	5	6
982	1x26	1x29	1.56208	No	No	0	0	2
983	6x29	6x30	1.54775	No	No	0	5	6
984	1x47	2x55	1.5272	No	No	0	7	3
985	b.b16x2	b.l17x1	1.51924	No	No	0	5	2
986	b.lh12x2	b.lh12x3	1.51024	No	No	0	8	4
987	2x60	3x28	1.5011	Yes	No	0	6	7
988	G.HN.34	G.HN.38	1.49336	No	Yes	0	4	2
989	4x59	5x421	1.47776	No	No	0	5	8
990	6x28	6x31	1.46836	No	No	0	7	7
991	b.1x4	g.h1x8	1.44601	Yes	No	0	8	7
992	2x59	3x28	1.44097	No	No	0	5	7
993	b.1x1	g.h1x1	1.43391	Yes	Yes	0	4	2
994	b.b20x1	b.l21x5	1.4197	No	No	0	5	4
995	4x50	4x51	1.41784	Yes	No	0	9	6
996	G.H1.03	G.s6h5.03	1.41751	No	No	0	9	9
997	6x25	6x28	1.41063	No	No	0	0	7
998	b.1x4	b.1x8	1.3955	Yes	No	0	8	5
999	1x30	1x34	1.37876	No	No	0	2	4
1000	b.b21x3	b.l17x2	1.37633	Yes	No	0	6	6
1001	g.ctx6	g.ctx7	1.37579	Yes	No	0	6	4
1002	G.H1.05	G.S3.07	1.35154	No	Yes	0	7	9
1003	3x23	3x26	1.33577	No	Yes	0	3	8
1004	5x49	5x53	1.3352	No	No	0	4	6
1005	g.h1x1	g.ntx1	1.32855	Yes	No	0	2	4
1006	G.h4s6.02	G.h4s6.03	1.32343	No	No	0	7	4
1007	1x22	NT	1.31899	No	Yes	0	0	4
1008	6x26	6x29	1.3188	No	No	0	0	5
1009	2x67	E1	1.26827	No	Yes	0	3	3
1010	b.ntx1	g.h1x1	1.25181	No	Yes	0	5	2
1011	G.HG.13	G.HG.16	1.24309	No	No	0	7	4
1012	6x51	7x32	1.1921	Yes	No	0	7	4
1013	2x63	3x28	1.18877	No	No	0	4	7
1014	6x34	6x38	1.18014	No	No	0	8	8
1015	b.lhb1x6	b.lhb1x7	1.1741	Yes	No	0	3	1
1016	G.S5.07	G.s1h1.06	1.1725	Yes	No	0	9	9
1017	b.lhb1x1	b.lhb1x2	1.14794	No	No	0	1	1
1018	G.HG.03	G.HG.06	1.1409	No	No	0	6	6
1019	g.ctx6	g.h2x16	1.13083	Yes	No	0	6	4
1020	1x41	1x45	1.11636	No	No	0	5	5
1021	4x54	4x55	1.11613	No	No	0	3	4
1022	b.l21x2	b.l21x3	1.07773	Yes	No	0	4	3
1023	b.1x3	b.ntx3	1.0497	No	No	0	1	0
1024	G.H3.01	G.s4h3.14	1.04189	Yes	No	0	9	6
1025	6x27	6x31	1.03552	No	No	0	0	7
1026	G.HN.38	G.HN.42	1.017	Yes	No	0	2	5
1027	G.s3h2.01	G.s3h2.02	0.9757	No	No	0	9	9
1028	G.H5.01	G.H5.02	0.967257	No	No	0	9	4
1029	G.S4.07	G.s1h1.04	0.966657	No	Yes	0	8	9
1030	G.s1h1.02	G.s1h1.05	0.954343	No	No	0	8	9
1031	G.HG.16	G.hgh4.06	0.946133	No	No	0	4	2
1032	4x44	4x48	0.945714	No	No	0	4	3
1033	5x66	5x70	0.94091	No	No	0	6	6
1034	G.H3.01	G.s4h3.03	0.938438	Yes	No	0	9	8
1035	G.hgh4.12	G.hgh4.13	0.933809	No	No	0	1	4
1036	G.H2.02	G.H2.04	0.9282	No	No	0	8	9
1037	G.s1h1.02	G.s1h1.03	0.926819	No	No	0	8	8
1038	7x27	E3	0.91999	No	Yes	0	4	4
1039	4x40	G.HN.52	0.918571	No	No	0	5	3
1040	b.1x16	b.1x17	0.915286	No	No	0	4	2
1041	G.H1.03	G.H1.07	0.915124	No	Yes	0	9	9
1042	6x31	6x35	0.914029	No	No	0	7	8
1043	2x39	8x64	0.9134	Yes	No	0	9	4
1044	4x62	4x66	0.892729	No	No	0	4	3
1045	b.1x4	b.ntx4	0.8748	Yes	No	0	8	0
1046	8x63	b.l25x4	0.8574	No	Yes	0	4	5
1047	1x36	1x37	0.847033	Yes	No	0	5	4
1048	6x48	7x57	0.844	Yes	No	0	8	0
1049	5x72	G.H5.17	0.84379	No	Yes	0	6	5
1050	G.H1.07	G.s6h5.04	0.838248	Yes	No	0	9	9
1051	3x57	G.H5.19	0.8228	No	Yes	0	0	8
1052	8x48	8x51	0.822438	No	No	0	6	7
1053	g.h1x6	g.h1x9	0.806857	No	No	0	4	6
1054	3x24	3x27	0.783676	No	No	0	3	4
1055	G.HG.14	G.s4h3.12	0.7836	No	No	0	6	0
1056	b.b16x1	b.l17x3	0.780057	No	Yes	0	4	9
1057	1x24	1x27	0.771952	No	No	0	0	0
1058	b.1x1	g.ntx3	0.763543	Yes	No	0	4	0
1059	G.hns1.03	I2	0.751267	No	Yes	0	5	7
1060	6x55	E3	0.733333	No	Yes	0	7	4
1061	H.HC.11	H.HE.06	0.7136	No	No	0	9	7
1062	G.HN.53	G.S1.01	0.711714	No	No	0	2	7
1063	6x56	7x37	0.7028	No	Yes	0	0	8
1064	G.H3.01	G.H3.04	0.691133	Yes	No	0	9	9
1065	G.H1.06	G.H1.07	0.683714	No	Yes	0	9	9
1066	G.HN.26	G.HN.29	0.680267	No	No	0	0	2
1067	g.h1x12	g.l1x1	0.678381	Yes	No	0	6	1
1068	6x38	6x41	0.670819	No	No	0	8	8
1069	g.h1x3	g.h1x7	0.651067	No	No	0	3	2
1070	1x23	1x25	0.644857	No	No	0	0	0
1071	b.l8x4	b.l8x5	0.628324	No	No	0	3	3
1072	g.h1x2	g.h1x5	0.605943	No	Yes	0	2	6
1073	5x52	5x56	0.571314	No	No	0	4	5
1074	G.HN.27	G.HN.28	0.563	No	No	0	0	2
1075	1x64	8x53	0.5596	No	No	0	0	8
1076	H.hbhc.04	H.hbhc.14	0.557333	Yes	No	0	3	4
1077	b.1x21	g.l1x4	0.557	No	Yes	0	3	8
1078	b.lhb1x2	b.lhb1x3	0.55331	No	Yes	0	1	2
1079	6x59	E3	0.5476	No	Yes	0	0	4
1080	H.HC.11	H.HD.04	0.5464	No	No	0	9	5
1081	1x40	2x62	0.538	No	No	0	7	3
1082	G.HG.10	G.HG.12	0.519981	No	No	0	5	3
1083	H.HE.04	H.HF.06	0.5076	Yes	No	0	9	7
1084	g.h2x6	g.h2x7	0.485467	No	No	0	2	5
1085	4x67	5x33	0.4628	No	No	0	3	0
1086	2x69	E1	0.454667	No	Yes	0	4	3
1087	H.HB.02	H.HB.06	0.4532	No	No	0	7	4
1088	5x71	G.H5.17	0.436838	No	Yes	0	7	5
1089	H.HB.08	H.HC.02	0.434	Yes	No	0	1	4
1090	2x71	E1	0.422	No	Yes	0	0	3
1091	G.hgh4.01	G.s4h3.05	0.418667	Yes	Yes	0	6	9
1092	1x55	1x56	0.415867	No	No	0	2	8
1093	G.h4s6.04	G.h4s6.08	0.413657	No	No	0	4	5
1094	H.HB.05	H.HC.06	0.3912	Yes	No	0	3	5
1095	H.HA.29	H.HD.09	0.3888	No	Yes	0	6	8
1096	H.HD.09	H.HD.12	0.3876	Yes	No	0	8	8
1097	G.s1h1.04	H.hehf.07	0.3832	Yes	No	0	9	6
1098	8x48	8x52	0.379733	No	No	0	6	4
1099	b.ntx2	g.h1x5	0.3722	No	Yes	0	0	6
1100	2x62	2x66	0.369314	No	No	0	3	3
1101	H.HC.03	H.hbhc.04	0.3572	No	Yes	0	4	3
1102	b.1x17	b.1x20	0.348838	No	No	0	2	2
1103	G.S2.02	H.HA.04	0.347333	Yes	No	0	5	5
1104	H.HB.05	H.HC.10	0.340133	Yes	No	0	3	8
1105	b.1x1	g.ntx4	0.338771	Yes	No	0	4	0
1106	3x58	G.H5.20	0.332	No	Yes	0	0	8
1107	3x55	3x59	0.332	No	No	0	6	0
1108	H.HA.12	H.hbhc.14	0.330933	No	No	0	4	4
1109	G.s4h3.05	G.s4h3.06	0.3288	Yes	No	0	9	0
1110	8x67	b.l25x2	0.3286	No	No	0	0	5
1111	G.H1.07	G.H1.10	0.321657	Yes	No	0	9	9
1112	H.hehf.04	H.hehf.06	0.315333	Yes	No	0	9	9
1113	H.HD.12	H.hdhe.01	0.314267	No	Yes	0	8	6
1114	H.HC.02	H.HC.06	0.311733	No	No	0	4	5
1115	H.HF.02	H.HF.06	0.311467	No	No	0	8	7
1116	H.HB.04	H.HB.07	0.302533	No	No	0	1	2
1117	H.HB.12	H.hbhc.04	0.2972	No	Yes	0	3	3
1118	H.HE.04	H.HE.08	0.286667	Yes	No	0	9	4
1119	G.H1.12	G.S2.06	0.286533	No	No	0	8	9
1120	H.HA.16	H.hbhc.04	0.281333	No	Yes	0	4	3
1121	G.HG.12	G.s4h3.05	0.2796	No	Yes	0	3	9
1122	G.H1.02	H.HF.01	0.2692	No	No	0	9	5
1123	b.b1x4	g.ctx18	0.2636	Yes	No	0	7	0
1124	H.HC.05	H.HC.06	0.262533	No	No	0	1	5
1125	2x70	3x32	0.2584	No	Yes	0	0	6
1126	b.b25x7	g.b28x6	0.258133	Yes	No	0	7	0
1127	G.HN.35	G.HN.38	0.2567	No	Yes	0	4	2
1128	4x68	5x36	0.2516	No	No	0	6	0
1129	G.H3.08	G.H3.11	0.2496	Yes	No	0	8	8
1130	G.HG.10	G.HG.11	0.247	No	No	0	5	5
1131	H.HE.04	H.HF.03	0.2452	Yes	No	0	9	9
1132	H.HE.03	H.HE.07	0.2436	No	No	0	3	5
1133	H.HA.26	H.hahb.04	0.243467	No	Yes	0	8	7
1134	g.l1x3	g.l1x5	0.242667	No	No	0	1	4
1135	H.HA.06	H.HA.07	0.240267	No	No	0	3	5
1136	G.hfs2.04	H.HF.04	0.24	No	No	0	7	7
1137	H.HB.04	H.HB.08	0.233867	No	Yes	0	1	1
1138	H.HB.08	H.HC.03	0.233867	Yes	No	0	1	4
1139	H.HE.12	H.hehf.04	0.2256	No	Yes	0	7	9
1140	G.s1h1.04	H.HF.03	0.2252	Yes	No	0	9	9
1141	7x58	7x59	0.2236	No	No	0	0	0
1142	G.hfs2.03	H.HA.07	0.222533	No	No	0	6	5
1143	5x33	5x35	0.2216	No	No	0	0	0
1144	H.HD.10	H.hdhe.01	0.2204	No	Yes	0	8	6
1145	1x61	2x47	0.2196	No	No	0	0	8
1146	H.HB.03	H.HB.05	0.218	No	Yes	0	3	3
1147	G.HN.38	G.HN.39	0.2114	Yes	No	0	2	4
1148	H.HA.14	H.HE.05	0.209333	No	Yes	0	9	7
1149	H.HA.11	H.HE.05	0.200933	No	Yes	0	7	7
1150	1x60	7x58	0.1964	Yes	No	0	7	0
1151	G.hgh4.18	G.hgh4.19	0.196233	No	No	0	1	7
1152	H.hbhc.04	H.hbhc.15	0.192667	Yes	No	0	3	4
1153	1x62	2x51	0.1904	No	No	0	0	7
1154	H.HA.08	H.hehf.06	0.188533	No	No	0	4	9
1155	G.H1.06	H.hehf.05	0.182133	No	No	0	9	3
1156	H.HA.03	H.HA.07	0.18	No	No	0	8	5
1157	H.HA.29	H.hahb.04	0.1788	No	Yes	0	6	7
1158	H.HC.03	H.HC.04	0.1788	No	No	0	4	3
1159	H.HA.22	H.HD.07	0.177333	No	Yes	0	7	4
1160	b.b1x3	g.b28x7	0.1768	Yes	No	0	7	0
1161	H.HA.09	H.HA.13	0.176	No	No	0	3	6
1162	G.hfs2.03	H.HA.10	0.1752	No	No	0	6	5
1163	G.H3.01	G.s4h3.11	0.174667	Yes	No	0	9	0
1164	b.1x1	g.ntx2	0.17	Yes	No	0	4	4
1165	G.s1h1.04	G.s4h3.10	0.1692	Yes	No	0	9	0
1166	G.H1.11	G.H5.04	0.169124	No	No	0	9	8
1167	H.HF.03	H.hehf.04	0.168667	No	Yes	0	9	9
1168	H.HE.01	H.HE.05	0.1676	No	Yes	0	9	7
1169	H.HB.05	H.HC.09	0.165867	Yes	No	0	3	1
1170	H.HE.04	H.HE.05	0.165067	Yes	Yes	0	9	7
1171	H.HA.16	H.HA.20	0.162	No	No	0	4	5
1172	H.HD.06	H.hahb.04	0.159333	No	Yes	0	5	7
1173	G.hfs2.01	G.hfs2.03	0.159333	No	No	0	7	6
1174	H.HD.03	H.hchd.01	0.155733	No	No	0	6	9
1175	H.HA.17	H.HA.21	0.150533	No	No	0	5	4
1176	G.hfs2.05	G.hfs2.06	0.149333	No	No	0	9	7
1177	H.HC.11	H.HE.07	0.1488	No	No	0	9	5
1178	1x47	1x48	0.146943	No	No	0	7	3
1179	7x40	7x44	0.146	No	No	0	6	0
1180	H.HF.05	H.HF.06	0.145733	No	No	0	9	7
1181	A:A:Y253	G.HG.15	0.145067	No	No	0	0	7
1182	H.hahb.06	H.hchd.01	0.1448	Yes	No	0	4	9
1183	H.HA.23	H.HB.09	0.143333	No	No	0	5	4
1184	G.hfs2.02	H.hdhe.05	0.142933	No	No	0	9	9
1185	H.hahb.01	H.hahb.02	0.141333	No	No	0	1	8
1186	H.HC.12	H.HD.04	0.1396	No	No	0	1	5
1187	H.HA.19	H.HB.09	0.137467	No	No	0	6	4
1188	H.HC.08	H.HE.09	0.135733	Yes	No	0	3	4
1189	H.HD.07	H.HE.03	0.135333	Yes	No	0	4	3
1190	H.HA.15	H.HE.09	0.1332	No	No	0	6	4
1191	H.HA.22	H.HD.06	0.130933	No	No	0	7	5
1192	H.HC.08	H.HE.10	0.129067	Yes	No	0	3	4
1193	H.HD.11	H.hdhe.03	0.128133	No	No	0	7	8
1194	3x21	E1	0.124781	No	Yes	0	0	3
1195	H.HA.25	H.hdhe.01	0.124533	No	Yes	0	8	6
1196	g.h2x10	g.h2x13	0.123676	No	No	0	3	1
1197	H.hbhc.01	H.hbhc.04	0.122267	No	Yes	0	3	3
1198	6x54	6x58	0.1216	No	No	0	5	0
1199	H.HD.01	H.hahb.07	0.120667	No	No	0	1	1
1200	H.HB.06	H.HC.10	0.1192	No	No	0	4	8
1201	H.HA.23	H.HB.10	0.1192	No	No	0	5	2
1202	H.HE.11	H.hehf.04	0.117867	No	Yes	0	8	9
1203	g.h1x3	g.ntx8	0.1156	No	No	0	3	0
1204	H.HC.08	H.HE.13	0.114933	Yes	No	0	3	3
1205	H.HA.19	H.HE.06	0.114133	No	No	0	6	7
1206	H.HC.04	H.HE.12	0.112933	No	No	0	3	7
1207	H.HC.04	H.HE.13	0.111467	No	No	0	3	3
1208	H.hahb.06	H.hahb.08	0.109867	Yes	No	0	4	3
1209	H.HF.04	H.hehf.06	0.109467	No	No	0	7	9
1210	H.HD.07	H.hdhe.03	0.109333	Yes	No	0	4	8
1211	H.hahb.08	H.hahb.09	0.108667	No	No	0	3	1
1212	H.HE.13	H.hehf.01	0.108533	No	No	0	3	1
1213	H.HC.08	H.HC.12	0.108	Yes	No	0	3	1
1214	H.HD.07	H.HE.02	0.106667	Yes	No	0	4	8
1215	H.hahb.07	H.hchd.01	0.102933	No	No	0	1	9
1216	H.HA.27	H.HA.28	0.0993333	No	No	0	1	3
1217	5x34	5x38	0.0988	No	No	0	0	5
1218	H.HA.26	H.hahb.06	0.0941333	No	Yes	0	8	4
1219	H.hbhc.01	H.hbhc.02	0.0941333	No	No	0	3	2
1220	H.hdhe.04	H.hdhe.05	0.0933333	No	No	0	7	9
1221	8x61	8x65	0.0927714	No	No	0	4	0
1222	b.l21x6	b.l21x7	0.0905905	No	Yes	0	3	5
1223	G.hfs2.01	H.HA.11	0.0872	No	No	0	7	7
1224	G.s4h3.05	G.s4h3.07	0.0788	Yes	No	0	9	0
1225	H.HA.28	H.hdhe.01	0.0774667	No	Yes	0	3	6
1226	H.HD.09	H.hahb.02	0.0768	Yes	No	0	8	8
1227	G.s4h3.08	G.s4h3.12	0.0754667	No	No	0	0	0
1228	H.HD.02	H.hahb.04	0.0736	No	Yes	0	5	7
1229	H.HA.10	H.HA.13	0.0718667	No	No	0	5	6
1230	A:A:S252	G.H3.01	0.0702667	No	Yes	0	0	9
1231	H.hehf.01	H.hehf.03	0.0696	No	No	0	1	3
1232	4x59	5x381	0.068	No	No	0	5	0
1233	3x56	3x60	0.0672	No	No	0	5	0
1234	H.HE.01	H.hdhe.04	0.0654667	No	No	0	9	7
1235	H.HA.19	H.HC.07	0.0649333	No	No	0	6	6
1236	5x47	6x57	0.0648	No	No	0	7	0
1237	2x38	8x68	0.0644	Yes	No	0	7	0
1238	G.H1.06	H.HA.05	0.0642667	No	No	0	9	2
1239	A:A:S366	G.H1.03	0.064	No	No	0	0	9
1240	H.HD.08	H.HD.09	0.062	No	Yes	0	3	8
1241	G.S2.05	G.h1ha.01	0.0606667	No	No	0	4	0
1242	7x55	7x60	0.0596	Yes	No	0	8	0
1243	1x59	1x63	0.0572	No	No	0	1	0
1244	H.HA.20	H.HB.13	0.0541333	No	No	0	5	3
1245	H.hahb.05	H.hahb.06	0.0530667	No	Yes	0	1	4
1246	H.HB.01	H.hahb.08	0.0525333	No	No	0	1	3
1247	H.hahb.02	H.hahb.03	0.052	No	No	0	8	8
1248	H.HC.01	H.hbhc.15	0.052	No	No	0	1	4
1249	H.HB.08	H.HB.11	0.0509333	Yes	No	0	1	1
1250	H.HA.18	H.HE.02	0.0477333	No	No	0	7	8
1251	A:A:N254	G.hgh4.01	0.0465333	No	Yes	0	0	6
1252	H.HD.05	H.hahb.04	0.0452	No	Yes	0	3	7
1253	H.hbhc.02	H.hbhc.03	0.0429333	No	No	0	2	3
1254	H.hbhc.13	H.hbhc.15	0.0429333	No	No	0	1	4
1255	G.hgh4.09	G.hgh4.12	0.0402857	No	No	0	5	1
1256	H.HA.21	H.hdhe.03	0.0393333	No	No	0	4	8
1257	5x73	G.h4s6.03	0.0392	No	No	0	0	4
1258	3x20	E1	0.0354667	No	Yes	0	0	3
1259	H.HA.24	H.HA.28	0.0208	No	No	0	3	3
1260	H.hehf.02	H.hehf.03	0.0205333	No	No	0	1	3
1261	G.s4h3.07	G.s4h3.09	0.0174667	No	No	0	0	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	G.HN.38	1.06151	5	0	2
2	G.hns1.01	7.32237	5	14	4
3	G.S1.02	5.85408	4	3	6
4	G.s1h1.04	1.24179	5	0	9
5	G.H1.07	0.689686	4	0	9
6	H.hahb.04	0.14008	5	0	7
7	H.hahb.06	0.100467	4	0	4
8	H.HB.05	0.2788	4	0	3
9	H.HB.08	0.238167	4	0	1
10	H.hbhc.04	0.301333	6	0	3
11	H.HC.08	0.121933	4	0	3
12	H.HD.07	0.132167	4	0	4
13	H.HD.09	0.2288	4	0	8
14	H.hdhe.01	0.184167	4	0	6
15	H.HE.04	0.301133	4	0	9
16	H.HE.05	0.185733	4	0	7
17	H.hehf.04	0.206867	4	0	9
18	G.S2.02	1.92761	4	0	5
19	G.S3.03	5.9545	6	3	8
20	G.S3.04	10.846	4	15	7
21	G.S3.06	9.57983	5	15	7
22	G.S3.07	3.68693	4	0	9
23	G.H2.06	5.97604	6	2	9
24	G.H2.07	5.81821	6	2	9
25	G.h2s4.01	9.67747	4	0	9
26	G.S4.04	4.26893	4	0	9
27	G.s4h3.05	0.276467	4	0	9
28	G.H3.01	1.30852	7	0	9
29	G.H3.08	4.81379	4	0	8
30	G.H3.09	5.20518	6	16	9
31	G.H3.13	9.27301	5	16	6
32	G.H3.17	10.6887	5	2	5
33	G.S5.05	4.59743	4	18	9
34	G.S5.07	2.55036	6	0	9
35	G.hgh4.01	5.40657	4	0	6
36	G.hgh4.04	2.95453	4	17	6
37	G.hgh4.05	8.34263	5	0	6
38	G.hgh4.08	7.54951	4	0	6
39	G.hgh4.11	3.91579	4	0	5
40	G.hgh4.20	6.31894	4	0	3
41	G.hgh4.21	4.34484	4	0	4
42	G.H4.03	2.8585	4	0	4
43	G.H4.08	6.47554	4	8	3
44	G.H4.10	9.62753	5	17	7
45	G.H4.12	5.58713	5	8	4
46	G.H4.14	6.85788	4	17	5
47	G.H4.15	7.98879	4	0	8
48	G.h4s6.12	5.52591	4	0	2
49	G.h4s6.20	5.9588	4	0	4
50	G.S6.02	9.49158	4	0	8
51	G.S6.05	6.56644	5	8	5
52	G.H5.03	4.29979	4	18	9
53	G.H5.05	5.48875	4	3	5
54	G.H5.08	5.69401	6	3	8
55	G.H5.17	5.957	7	3	5
56	G.H5.19	4.93802	4	0	8
57	G.H5.20	3.66711	5	0	8
58	b.1x1	1.06561	5	0	4
59	b.1x4	1.79588	5	0	8
60	b.h2x1	4.23109	4	0	5
61	b.h2x5	3.46774	4	0	5
62	b.lhb1x3	3.35776	4	0	2
63	b.lhb1x6	4.71458	4	12	3
64	b.b1x3	5.12997	4	0	7
65	b.b1x4	4.03405	4	7	7
66	b.l1x3	9.24683	5	4	9
67	b.l1x6	10.6963	5	2	9
68	b.b2x1	7.89242	5	2	8
69	b.b2x5	6.35541	6	4	7
70	b.b3x3	3.86314	5	9	8
71	b.l3x1	9.10826	4	2	9
72	b.l3x2	7.86621	4	14	9
73	b.b4x2	5.39199	4	0	8
74	b.b4x3	4.90495	4	9	7
75	b.b4x6	9.01343	7	4	9
76	b.b4x7	8.90929	4	4	8
77	b.b5x2	8.75234	4	4	7
78	b.b5x3	6.07645	6	4	9
79	b.b5x7	5.7009	4	0	7
80	b.l5x1	4.40113	5	9	8
81	b.l5x5	10.0766	5	0	9
82	b.b6x1	5.13124	4	2	9
83	b.b6x5	3.91548	6	9	6
84	b.l6x5	5.18161	4	13	4
85	b.b7x1	5.37352	5	13	4
86	b.b8x4	5.59219	5	9	6
87	b.l9x3	6.61025	6	2	9
88	b.l9x6	5.73803	8	2	8
89	b.b10x5	4.65676	6	0	9
90	b.l11x2	7.72206	4	2	9
91	b.b12x5	4.28229	4	0	6
92	b.b12x6	8.88152	6	2	8
93	b.b13x7	7.98937	5	6	7
94	b.l13x3	7.75086	6	6	9
95	b.l13x6	6.02214	5	2	9
96	b.b14x3	3.98653	4	6	5
97	b.b15x1	8.26613	4	6	9
98	b.l15x1	5.49193	5	2	7
99	b.l15x2	6.47102	4	6	9
100	b.b16x4	10.2883	4	6	6
101	b.b16x6	7.97507	7	6	8
102	b.b17x5	7.10054	4	5	7
103	b.b17x7	8.17913	4	5	8
104	b.l17x3	9.24541	6	5	9
105	b.l17x6	7.8347	5	2	9
106	b.b18x3	5.16525	4	5	8
107	b.l18x1	7.20764	6	11	6
108	b.l18x2	5.98367	4	11	7
109	b.l18x3	7.32548	4	11	5
110	b.b19x2	7.02595	6	5	6
111	b.b19x4	6.31964	4	5	8
112	b.l19x1	6.72291	4	2	9
113	b.l19x2	8.60949	4	5	9
114	b.b20x2	6.80812	4	5	6
115	b.b20x4	11.6426	5	5	8
116	b.b20x6	7.42319	5	5	6
117	b.b21x1	7.50345	5	5	7
118	b.b21x3	7.03001	4	5	6
119	b.b21x5	6.06572	4	0	4
120	b.b21x7	6.02541	6	0	5
121	b.l21x2	5.47852	4	0	4
122	b.l21x7	3.44844	4	2	5
123	b.l22x5	7.64181	5	12	9
124	b.b23x1	3.94295	4	0	5
125	b.b23x6	6.87828	7	2	7
126	b.l23x1	6.51013	4	2	6
127	b.b24x4	8.27198	4	2	6
128	b.b24x6	6.92352	4	2	8
129	b.l24x3	4.71925	4	0	5
130	b.b25x7	7.27335	4	0	7
131	b.l25x3	8.84328	5	10	9
132	b.l25x4	4.72248	4	0	5
133	b.l25x6	12.4702	5	2	8
134	b.l28x1	10.7264	7	2	9
135	b.l28x2	7.98038	4	10	9
136	b.b28x3	4.53281	5	4	7
137	b.b28x4	7.89337	4	10	6
138	b.b28x6	8.66641	5	10	9
139	g.h1x1	1.73047	4	0	2
140	g.h1x5	1.73109	4	0	6
141	g.h1x12	1.77607	4	0	6
142	g.l1x4	5.08588	5	5	8
143	g.h2x11	9.2346	4	11	6
144	g.ctx3	6.21481	5	0	9
145	g.ctx6	3.39118	6	12	6
146	g.ctx14	5.63724	4	7	9
147	g.ctx15	7.1311	4	7	9
148	g.ctx16	5.30722	8	7	8
149	NT	115.172	9	1	4
150	1x36	3.10783	5	1	5
151	1x39	3.65903	7	1	7
152	1x43	5.98306	6	1	7
153	1x50	3.9669	4	0	9
154	1x60	3.30789	6	0	7
155	2x38	2.94806	4	0	7
156	2x39	5.20893	5	0	9
157	2x50	6.29561	6	0	8
158	2x53	5.54188	5	1	8
159	2x57	5.25967	5	1	7
160	2x60	4.39877	4	1	6
161	E1	5.96013	15	1	3
162	3x26	7.59207	4	1	8
163	3x32	4.49128	5	1	6
164	3x33	5.13557	5	1	7
165	3x34	4.05634	4	0	9
166	3x35	4.62685	4	0	5
167	3x40	6.11353	6	1	8
168	3x42	8.62911	5	21	9
169	3x44	3.92841	4	0	8
170	3x46	7.65091	4	0	9
171	3x49	5.02728	5	19	8
172	I2	5.09698	12	3	7
173	4x50	5.6196	5	21	9
174	4x60	6.0569	5	1	8
175	4x64	8.59859	4	1	8
176	E2	9.13878	10	1	5
177	E2x51	8.2244	6	1	8
178	5x40	2.65039	6	1	4
179	5x44	6.00741	4	1	6
180	5x58	5.01623	4	20	9
181	6x44	4.07836	5	20	9
182	6x48	6.03309	6	1	8
183	6x51	3.87012	5	1	7
184	E3	3.94827	11	1	4
185	7x33	4.87667	4	1	7
186	7x37	4.36207	4	1	8
187	7x45	5.37997	4	1	9
188	7x55	2.63752	4	0	8
189	8x58	2.6145	4	0	5
190	Lig	12.6082	36	1	0
191	I3	4.31364	5	3	5

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	b.l22x1	g.ctx3	10.1824	8.50715	No	Yes	0	9	9
2	b.l22x1	g.ctx5	13.2064	3.19782	No	No	0	9	9
3	b.lhb1x11	g.ctx5	13.2305	4.77997	No	No	0	4	9
4	b.b25x7	b.lhb1x11	13.2605	5.91591	Yes	No	0	7	4
5	b.b25x7	b.b28x6	13.0646	17.7652	Yes	Yes	0	7	9
6	b.b28x4	b.b28x6	41.0754	6.14358	Yes	Yes	10	6	9
7	b.b1x5	b.b28x4	70.0173	7.37533	No	Yes	0	3	6
8	b.b1x5	b.l1x1	69.9448	10.5171	No	No	0	3	7
9	I1x48	b.l1x1	100	10.6202	No	No	0	8	7
10	I1x48	I1x51	99.8933	3.6583	No	No	0	8	7
11	2x41	I1x51	99.7741	4.07173	No	No	0	6	7
12	2x41	4x43	99.6548	3.78866	No	No	0	6	6
13	2x38	4x43	70.0407	3.23262	Yes	No	0	7	6
14	2x38	3x49	69.6638	5.36907	Yes	Yes	0	7	8
15	3x49	3x53	52.2149	7.66392	Yes	No	0	8	8
16	3x53	G.H5.19	52.0665	11.9094	No	Yes	0	8	8
17	G.H5.15	G.H5.19	51.8291	3.49768	No	Yes	0	8	8
18	G.S3.06	b.l5x5	10.4702	18.1519	Yes	Yes	0	7	9
19	G.h2s4.01	b.l5x5	31.5246	12.922	Yes	Yes	0	9	9
20	G.S1.05	G.h2s4.01	30.6464	19.0894	No	Yes	0	9	9
21	G.S1.05	G.S1.07	29.9119	3.37088	No	No	0	9	8
22	G.S1.07	G.S4.04	29.6673	3.19318	No	Yes	0	8	9
23	G.S4.07	G.s1h1.04	37.1505	0.966657	No	Yes	0	8	9
24	G.S4.07	G.s5hg.01	37.5162	1.986	No	No	0	8	9
25	G.S5.07	G.s5hg.01	38.7423	2.92125	Yes	No	0	9	9
26	G.S5.07	G.s6h5.01	43.7522	3.80701	Yes	No	0	9	9
27	G.S5.05	G.s6h5.01	44.0961	5.83969	Yes	No	18	9	9
28	G.S5.03	G.S5.05	22.8733	3.38937	No	Yes	0	9	9
29	G.H5.10	G.S5.03	23.224	8.33683	No	No	0	7	9
30	G.H5.10	G.S6.02	47.5633	14.5573	No	Yes	0	7	8
31	G.H5.13	G.S6.02	45.4468	10.5357	No	Yes	0	8	8
32	5x68	G.H5.13	43.0148	8.23277	No	No	3	9	8
33	5x68	G.H5.16	45.1202	6.53417	No	No	3	9	6
34	G.H5.16	I2	45.255	3.5608	No	Yes	3	6	7
35	G.H5.15	I2	47.3013	4.02144	No	Yes	3	8	7
36	G.S5.05	G.S6.04	22.8662	4.94966	Yes	No	0	9	9
37	G.H5.10	G.S6.04	24.1719	11.6357	No	No	0	7	9
38	b.b11x5	b.b14x3	19.5211	4.07585	No	Yes	0	6	5
39	b.b10x1	b.b11x5	33.0336	3.18238	No	No	0	9	6
40	b.b10x1	b.l9x6	33.1369	3.25464	No	Yes	0	9	8
41	G.H2.07	b.l9x6	18.5284	4.51882	Yes	Yes	2	9	8
42	G.H2.04	G.H2.07	17.3117	9.14238	No	Yes	0	9	9
43	G.H2.04	G.H3.08	17.0406	8.78099	No	Yes	0	9	8
44	b.l1x6	b.l28x1	20.1328	21.7386	Yes	Yes	2	9	9
45	b.l1x6	b.l3x1	19.9493	9.28226	Yes	Yes	2	9	9
46	b.l3x1	b.l5x5	39.6832	8.14989	Yes	Yes	0	9	9
47	b.l25x6	b.l28x1	86.7763	20.4614	Yes	Yes	2	8	9
48	b.b2x1	b.l28x1	70.3414	8.06874	Yes	Yes	2	8	9
49	b.b2x1	b.l3x1	19.9417	14.0985	Yes	Yes	2	8	9
50	b.b6x1	b.l9x6	50.1642	6.34058	Yes	Yes	2	9	8
51	G.H3.09	G.S4.04	20.8095	3.61193	Yes	Yes	0	9	9
52	G.S4.04	G.S5.04	25.2374	3.41485	Yes	No	0	9	9
53	G.H3.09	G.H4.15	13.1424	7.69898	Yes	Yes	0	9	8
54	G.H4.15	G.S5.04	13.1163	8.24497	Yes	No	0	8	9
55	G.H3.06	G.H4.15	24.0035	10.1605	No	Yes	0	6	8
56	G.H4.10	G.H4.14	11.4719	9.4476	Yes	Yes	17	7	5
57	G.H3.06	G.H4.14	15.1335	4.28356	No	Yes	0	6	5
58	b.l23x1	b.l25x6	10.9893	11.6352	Yes	Yes	2	6	8
59	G.S5.04	G.S5.06	11.864	4.11028	No	No	0	9	8
60	G.S5.06	G.S6.05	11.4987	3.68029	No	Yes	0	8	5
61	6x43	6x44	10.2191	3.11326	No	Yes	0	9	9
62	3x46	6x43	11.6187	7.44348	Yes	No	0	9	9
63	2x42	3x46	14.6506	5.22236	No	Yes	0	8	9
64	2x42	3x49	14.799	4.60227	No	Yes	19	8	8
65	b.l25x3	b.l28x2	31.7382	7.45813	Yes	Yes	10	9	9
66	b.b27x3	b.l25x3	60.3572	7.77146	No	Yes	0	8	9
67	b.b27x3	b.b28x6	30.6407	7.883	No	Yes	0	8	9
68	b.b28x4	b.l25x3	29.7448	11.6877	Yes	Yes	10	6	9
69	b.b12x5	b.l16x1	22.9694	2.41238	Yes	No	0	6	4
70	b.l16x1	b.l16x2	22.7102	2.66373	No	No	0	4	9
71	b.l14x5	b.l16x2	22.4509	9.26159	No	No	0	5	9
72	b.l14x3	b.l14x5	22.1915	7.41471	No	No	0	5	5
73	b.l14x1	b.l14x3	21.932	2.71868	No	No	0	4	5
74	b.b18x5	b.l14x1	21.6724	4.68072	No	No	0	5	4
75	b.b15x2	b.b18x5	21.1529	9.10078	No	No	0	6	5
76	b.b15x2	b.b19x2	18.2548	10.1449	No	Yes	5	6	6
77	b.b17x7	b.b19x2	12.9905	10.5149	Yes	Yes	5	8	6
78	b.b17x7	b.b21x1	12.2548	4.13746	Yes	Yes	5	8	7
79	b.1x19	b.b21x1	10.6988	8.36776	No	Yes	0	6	7
80	b.b28x2	b.l28x2	30.3169	11.2544	No	Yes	0	4	9
81	b.b28x2	b.l1x1	30.2416	8.28656	No	No	0	4	7
82	b.b14x3	b.b15x1	12.481	3.6413	Yes	Yes	6	5	9
83	b.b11x5	b.l13x7	13.653	5.36559	No	No	0	6	9
84	b.b12x3	b.l13x7	11.4724	3.62409	No	No	0	8	9
85	b.b13x7	b.b15x1	11.6235	11.1647	Yes	Yes	6	7	9
86	b.b12x3	b.b13x7	11.354	4.03173	No	Yes	0	8	7
87	b.b12x5	b.b13x5	22.2624	5.03867	Yes	No	0	6	4
88	b.b13x5	b.b13x7	22.5042	6.10823	No	Yes	0	4	7
89	b.b21x7	b.b24x6	10.1563	9.74269	Yes	Yes	0	5	8
90	b.b23x6	b.b24x6	10.4311	6.8949	Yes	Yes	2	7	8
91	b.l21x7	b.l23x1	14.6277	3.22315	Yes	Yes	2	5	6
92	b.b23x6	b.l21x7	13.4543	3.16511	Yes	Yes	2	7	5
93	b.b22x1	b.l25x6	89.9997	7.00068	No	Yes	0	8	8
94	b.b26x3	b.b27x3	90.1698	3.63308	No	No	0	6	8
95	b.b22x2	b.b26x3	90.1083	4.94135	No	No	0	8	6
96	b.b22x1	b.b22x2	90.0518	3.37905	No	No	0	8	8
97	4x43	4x47	30.5004	3.1969	No	No	0	6	5
98	2x45	4x47	30.3357	5.01295	No	No	0	9	5
99	2x45	3x42	26.583	13.1765	No	Yes	21	9	9
100	2x49	3x42	26.3432	3.44628	No	Yes	0	9	9
101	2x49	3x39	26.2308	4.24801	No	No	0	9	9
102	2x53	3x39	24.5067	9.07699	Yes	No	0	8	9
103	2x53	Lig	20.0276	3.35082	Yes	Yes	1	8	0
104	2x46	3x46	10.0195	8.40862	No	Yes	0	9	9
105	G.s1h1.04	H.HF.03	33.9538	0.2252	Yes	No	0	9	9
106	H.HF.03	H.hehf.04	27.4717	0.168667	No	Yes	0	9	9
107	H.HE.12	H.hehf.04	25.6197	0.2256	No	Yes	0	7	9
108	H.HC.04	H.HE.12	25.311	0.112933	No	No	0	3	7
109	H.HC.04	H.HE.13	16.6682	0.111467	No	No	0	3	3
110	H.HC.08	H.HE.13	15.4336	0.114933	Yes	No	0	3	3
111	H.HC.08	H.HC.12	14.1989	0.108	Yes	No	0	3	1
112	H.HC.12	H.HD.04	13.8902	0.1396	No	No	0	1	5
113	H.HC.11	H.HD.04	13.5815	0.5464	No	No	0	9	5
114	H.HC.11	H.HE.07	11.4208	0.1488	No	No	0	9	5
115	H.HE.03	H.HE.07	11.1122	0.2436	No	No	0	3	5
116	H.HD.07	H.HE.03	10.8035	0.135333	Yes	No	0	4	3
117	G.H3.08	G.S4.04	16.6787	6.85575	Yes	Yes	0	8	9
118	b.b2x1	b.b6x1	50.3048	5.89745	Yes	Yes	2	8	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
NT	NT	469.014	1	Yes	Yes	4	4	1	1
Lig	NT	73.1679	1	Yes	Yes	0	4	0	1
E1	NT	7.55387	1	Yes	Yes	3	4	1	1
1x29	Lig	8.52252	1	No	Yes	2	0	1	0
1x32	Lig	15.9597	1	No	Yes	5	0	1	0
1x35	7x35	3.25262	1	No	No	6	6	1	2
1x35	Lig	3.65769	1	No	Yes	6	0	1	0
1x36	1x39	3.2845	1	Yes	Yes	5	7	1	1
1x36	2x61	3.73493	1	Yes	No	5	7	1	2
1x36	Lig	4.79286	1	Yes	Yes	5	0	1	0
1x39	1x43	3.27249	1	Yes	Yes	7	7	1	1
1x39	2x57	3.09512	1	Yes	Yes	7	7	1	1
1x39	2x61	3.18982	1	Yes	No	7	7	1	2
1x39	7x38	4.23481	1	Yes	No	7	7	1	1
1x39	7x42	3.27769	1	Yes	No	7	9	1	2
1x39	Lig	5.25878	1	Yes	Yes	7	0	1	0
1x43	2x53	5.96417	1	Yes	Yes	7	8	1	1
1x43	2x54	4.01758	1	Yes	No	7	7	1	2
1x43	2x57	12.4621	1	Yes	Yes	7	7	1	1
1x43	7x42	5.77487	1	Yes	No	7	9	1	2
1x43	Lig	4.40711	1	Yes	Yes	7	0	1	0
2x53	3x36	5.71452	1	Yes	No	8	6	1	1
2x53	3x39	9.07699	1	Yes	No	8	9	1	2
2x53	3x40	3.60288	1	Yes	Yes	8	8	1	1
2x53	Lig	3.35082	1	Yes	Yes	8	0	1	0
2x57	2x61	3.8926	1	Yes	No	7	7	1	2
2x57	Lig	3.44571	1	Yes	Yes	7	0	1	0
2x60	3x32	7.40688	1	Yes	Yes	6	6	1	1
2x60	Lig	5.77343	1	Yes	Yes	6	0	1	0
E1	E1	20.115	1	Yes	Yes	3	3	1	1
E1	Lig	19.4369	1	Yes	Yes	3	0	1	0
3x25	E1	3.41027	1	No	Yes	9	3	2	1
E1	E2	4.34483	1	Yes	Yes	3	5	1	1
E1	E2x50	3.13093	1	Yes	No	3	9	1	2
3x25	E2x50	6.3336	1	No	No	9	9	2	2
3x26	E2	6.39606	1	Yes	Yes	8	5	2	1
3x26	E2x51	18.775	1	Yes	Yes	8	8	2	2
3x32	3x33	3.15707	1	Yes	Yes	6	7	1	1
3x32	Lig	8.23129	1	Yes	Yes	6	0	1	0
3x33	4x60	6.14867	1	Yes	Yes	7	8	1	2
3x33	5x43	8.25183	1	Yes	No	7	7	1	2
3x33	Lig	4.7409	1	Yes	Yes	7	0	1	0
3x36	3x40	4.88869	1	No	Yes	6	8	1	1
3x36	Lig	6.97232	1	No	Yes	6	0	1	0
3x40	5x47	10.2203	1	Yes	No	8	7	1	1
3x40	5x51	3.41995	1	Yes	No	8	7	1	2
3x40	6x48	11.4541	1	Yes	Yes	8	8	1	2
3x40	Lig	3.09523	1	Yes	Yes	8	0	1	0
4x60	E2x51	3.1869	1	Yes	Yes	8	8	2	2
4x60	5x43	9.21472	1	Yes	No	8	7	2	2
4x68	E2	11.898	1	No	Yes	6	5	2	1
E2	E2x51	5.49143	1	Yes	Yes	5	8	1	2
E2	E2	14.5475	1	Yes	Yes	5	5	1	1
E2x52	Lig	13.3905	1	No	Yes	5	0	1	0
E2	Lig	18.2261	1	Yes	Yes	5	0	1	0
5x41	E2	7.86826	1	No	Yes	6	5	1	1
5x41	5x44	6.04431	1	No	Yes	6	6	1	1
5x41	Lig	5.31622	1	No	Yes	6	0	1	0
5x42	5x44	5.87107	1	No	Yes	7	6	2	1
5x47	Lig	3.30043	1	No	Yes	7	0	1	0
5x51	6x48	3.49101	1	No	Yes	7	8	2	2
6x48	7x41	6.28515	1	Yes	No	8	6	2	1
6x51	7x33	6.62012	1	Yes	Yes	7	7	2	1
6x51	7x37	4.06716	1	Yes	Yes	7	8	2	1
E3	E3	7.57468	1	Yes	Yes	4	4	1	1
7x30	E3	5.08525	1	No	Yes	5	4	1	1
E3	Lig	8.64252	1	Yes	Yes	4	0	1	0
7x33	E3	3.31011	1	Yes	Yes	7	4	1	1
7x30	7x34	3.83779	1	No	No	5	5	1	1
7x30	Lig	5.01395	1	No	Yes	5	0	1	0
7x33	7x37	6.33462	1	Yes	Yes	7	8	1	1
7x34	Lig	6.80306	1	No	Yes	5	0	1	0
7x37	Lig	6.34371	1	Yes	Yes	8	0	1	0
7x38	Lig	8.82829	1	No	Yes	7	0	1	0
7x41	Lig	3.92269	1	No	Yes	6	0	1	0
2x57	3x32	3.4028	1	Yes	Yes	7	6	1	1
3x26	E1	3.8615	1	Yes	Yes	8	3	2	1
5x44	Lig	8.87703	1	Yes	Yes	6	0	1	0
1x28	Lig	3.51938	1	No	Yes	0	0	1	0
1x33	Lig	3.25678	0	No	Yes	3	0	1	0
3x29	3x33	3.37938	0	No	Yes	5	7	2	1
7x29	E3	4.33296	0	No	Yes	3	4	2	1
7x33	Lig	3.24184	1	Yes	Yes	7	0	1	0
5x40	E2	4.85156	1	Yes	Yes	4	5	2	1
1x31	1x32	4.50331	0	No	No	4	5	2	1
2x65	Lig	3.88179	0	No	Yes	4	0	1	0
1x25	NT	6.35883	1	No	Yes	0	4	2	1
5x42	E2	3.2166	1	No	Yes	7	5	2	1
1x24	NT	4.4713	1	No	Yes	0	4	2	1
E1	E2x52	3.3345	1	Yes	No	3	5	1	1
5x43	5x44	3.23724	1	No	Yes	7	6	2	1
1x28	NT	3.3268	1	No	Yes	0	4	1	1
2x60	2x64	2.91368	1	Yes	No	6	7	1	2
1x36	1x40	2.87985	1	Yes	No	5	7	1	2
6x54	E3	2.8457	1	No	Yes	5	4	2	1
6x52	Lig	2.55427	0	No	Yes	6	0	1	0
1x21	NT	2.31829	0	No	Yes	0	4	2	1
2x68	Lig	2.27688	0	No	Yes	3	0	1	0
6x53	Lig	2.1311	0	No	Yes	4	0	1	0
5x48	Lig	2.10334	0	No	Yes	4	0	1	0
7x28	E3	1.8642	0	No	Yes	2	4	2	1
3x24	E1	1.794	1	No	Yes	3	3	2	1
1x26	1x29	1.56208	0	No	No	0	2	2	1
2x60	3x28	1.5011	1	Yes	No	6	7	1	2
1x22	NT	1.31899	0	No	Yes	0	4	2	1
2x67	E1	1.26827	0	No	Yes	3	3	2	1
7x27	E3	0.91999	0	No	Yes	4	4	2	1
1x36	1x37	0.847033	1	Yes	No	5	4	1	2
6x55	E3	0.733333	0	No	Yes	7	4	2	1
6x56	7x37	0.7028	0	No	Yes	0	8	2	1
6x59	E3	0.5476	0	No	Yes	0	4	2	1
2x69	E1	0.454667	0	No	Yes	4	3	2	1
2x71	E1	0.422	0	No	Yes	0	3	2	1
2x70	3x32	0.2584	0	No	Yes	0	6	2	1
3x21	E1	0.124781	0	No	Yes	0	3	2	1
5x47	6x57	0.0648	1	No	No	7	0	1	2
3x20	E1	0.0354667	0	No	Yes	0	3	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
76.47	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/&β;1/&γ;2
74.29	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/&β;1/&γ;2
71.43	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/&β;1/&γ;1
71.05	Consensus	gs_pth	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7F16-PTH2-TIP39-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
68.57	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
67.65	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2
67.57	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2
67.57	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2
66.67	Single	8FLU	Long-acting PTH	8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2
65.79	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
65.71	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
65.71	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2
64.71	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/&β;1/&γ;2
64.71	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/&β;1/&γ;2
64.71	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
63.16	Consensus	gs_glucagon	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 6WZG-Secretin-Secretin-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2 7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2 7DTY-GIP-GIP-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
63.16	Consensus	gs_vip-pacap	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
62.86	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
62.86	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
62.50	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
62.16	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
61.54	Consensus	gs_class-b	Orthosteric Ligand	gs_class-b1 gs_class-b2
61.11	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2
61.11	Single	6LML	Glucagon	6LML-Glucagon-Glucagon
61.11	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
61.11	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/&β;1/&γ;2
61.11	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/&β;1/&γ;2
60.98	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on calcitonin_on vip-pacap_on pth_on crf_on
60.00	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/&β;1/&γ;2
60.00	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
60.00	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/&β;1/&γ;2
60.00	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
60.00	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2
60.00	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2
59.46	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
59.46	Consensus	gs_crf	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
58.54	Consensus	glucagon_on	Orthosteric Ligand	gip_on glu_on secretin_on ghrh_on glp_on
58.33	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2
58.33	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/&β;1/&γ;2
57.50	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
57.14	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2
57.14	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/&β;1/&γ;2
57.14	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/&β;1/&γ;2
57.14	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2
56.76	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/&β;1/&γ;2
56.76	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/&β;1/&γ;2
56.41	Consensus	vip-pacap_on	Orthosteric Ligand	vpac1_on vpac2_on pca1_on
55.56	Single	6NBF	Long-acting PTH analog	6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
55.56	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
55.56	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
54.29	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
54.29	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
54.05	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
54.05	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
54.05	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
54.05	Consensus	gs_cgrp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
53.85	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
52.94	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2
52.78	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2
52.78	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2
52.63	Single	6NBH	Long-acting PTH analog	6NBH-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
52.50	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2
51.35	Single	6FJ3	PTH	6FJ3-PTH1-PTH
51.22	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2
50.00	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
50.00	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
50.00	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/&β;1/&γ;2; RAMP3
50.00	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/&β;1/&γ;2
50.00	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2
50.00	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2
50.00	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2
50.00	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
48.78	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2
48.72	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
48.72	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
47.37	Single	6NBI	Long-acting PTH analog	6NBI-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
47.37	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
47.22	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
45.95	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
45.65	Consensus	gs_calcitonin	Orthosteric Ligand	gs_ct gs_cgrp
45.00	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP3
44.12	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2
43.90	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/&β;1/&γ;2
42.50	Consensus	go_class-b1	Orthosteric Ligand	go_crf
42.50	Consensus	go_crf	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
41.67	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2
41.03	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
41.03	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/&β;1/&γ;2
41.03	Consensus	vpac1_on	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
40.54	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
40.48	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
40.48	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
40.00	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/&β;1/&γ;2
39.47	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/&β;1/&γ;2
39.02	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
39.02	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
39.02	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
39.02	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
38.46	Consensus	go_class-b	Orthosteric Ligand	go_class-b1 go_class-b2
38.10	Consensus	calcitonin_on	Orthosteric Ligand	ct_on ctlike_on
38.10	Consensus	secretin_on	Orthosteric Ligand	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
38.10	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
37.50	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/&β;1/&γ;2
36.59	Consensus	class-d_on	Orthosteric Ligand	ste2_on
35.56	Consensus	pth1_on	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2
35.00	Consensus	pca1_on	Orthosteric Ligand	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
34.09	Consensus	gip_on_allo	Orthosteric Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
33.33	Consensus	ghrh_on	Orthosteric Ligand	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
33.33	Consensus	glp1_on_allo	Orthosteric Ligand	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
32.56	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
31.91	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
31.82	Consensus	glp1_on	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2 6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2 7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2 8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
31.58	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
31.37	Consensus	gs_ct	Orthosteric Ligand	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 7TYL-CT-Amylin-Gs/&β;1/&γ;2 8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
31.11	Consensus	gip_on	Orthosteric Ligand	7DTY-GIP-GIP-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
30.77	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2
30.23	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
30.00	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/&β;1/&γ;2
29.73	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/&β;1/&γ;2
29.55	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
28.89	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
28.89	Consensus	crf1_on	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
28.57	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
28.21	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/&β;1/&γ;2
28.21	Consensus	class-d_off	Orthosteric Ligand	ste2_off
28.21	Consensus	gs_adgr	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
28.21	Consensus	gs_class-b2	Orthosteric Ligand	gs_adgr
28.00	Consensus	ct_on	Orthosteric Ligand	7TYL-CT-Amylin-Gs/&β;1/&γ;2 7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
27.91	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
27.91	Consensus	gq_class-a	Orthosteric Ligand	gq_amine gq_peptide
27.50	Single	7QA8	Peptide	7QA8-STE2-Peptide
27.50	Single	7QA8	Peptide	7QA8-STE2-Peptide
27.50	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/&β;1/&γ;2
27.50	Consensus	class-d_off	Orthosteric Ligand	ste2_off
27.27	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
26.92	Consensus	glu_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2 6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2 8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2 8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2 7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2 6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
26.83	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
26.83	Single	8F7Q	Beta-endorphin	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2
26.32	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2
26.32	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
26.09	Consensus	peptide_on	Orthosteric Ligand	opioid_on angiotensin_on bombesin_on cck_on endothelin_on ghrelin_on npy_on nts_on orexin_on vasopressin-ot_on tachykinin_on sst_on relaxin_on trh_on nmur_on motilin_on melanocortin_on galanin_on fpr-alx_on compl-peptide_on bradykinin_on apelin_on
25.71	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/&β;1/&γ;2
25.64	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2
25.58	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
25.58	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.58	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
25.53	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/&β;1/&γ;2; RAMP2
25.53	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
25.53	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
25.00	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
25.00	Single	7XY6	PubChem 11717831	7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2
25.00	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/&β;1/&γ;2
25.00	Consensus	bk1_on	Orthosteric Ligand	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
24.53	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/&β;1/&γ;2
24.49	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2
24.44	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
24.44	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
24.44	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
24.39	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
24.39	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2
24.39	Consensus	apelin_on	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
24.39	Consensus	mop_off	Orthosteric Ligand	7UL4-μ-Alvimopan 4DKL-μ-Beta-funaltrexamine 8QOT-μ-Nanobody E
24.00	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
23.91	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
23.91	Single	7YOO	Neuropeptide Y	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
23.81	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
23.81	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
23.81	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/&β;1/&γ;2
23.81	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
23.81	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
23.81	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
23.81	Consensus	gi_lpl	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2 7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
23.68	Single	3UON	Quinuclidinyl benzilate hydrobromide	3UON-M₂-Quinuclidinyl benzilate hydrobromide
23.68	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
23.68	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
23.40	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_angiotensin gq_bombesin gq_bradykinin
23.40	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_motilin gs_neuromedin gs_orexin gs_sst gs_tachykinin gs_trh gs_vasopressin-ot gs_bombesin gs_bradykinin gs_compl-peptide gs_endothelin gs_galanin gs_ghrelin gs_melanocortin
23.26	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
23.26	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2
23.26	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
23.26	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
23.26	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
23.26	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
23.26	Consensus	gi_chemerin	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
23.26	Consensus	gi_formylpeptide	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2 7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
23.26	Consensus	gs_class-a	Orthosteric Ligand	gs_amine gs_nucleotide gs_lipid gs_peptide gs_protein gs_steroid
23.26	Consensus	opioid_on	Orthosteric Ligand	kop_on mop_on nop_on dop_on
23.08	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/&β;1/&γ;2
23.08	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
23.08	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
23.08	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
23.08	Consensus	cannabinoid_on	Orthosteric Ligand	cb1_on cb2_on
23.08	Consensus	cb1_on	Orthosteric Ligand	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
23.08	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
23.08	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2 8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
23.08	Consensus	gpr119_on	Orthosteric Ligand	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2 7WCN-GPR119-AR231453-Gs/&β;1/&γ;2 7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2 7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
22.92	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
22.92	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/&β;1/&γ;2
22.92	Consensus	gi_peptide	Orthosteric Ligand	gi_opioid gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_neuromedin gi_neurotensin gi_relaxin gi_neuropeptide gi_somatostatin gi_apelin gi_compl-peptide gi_cck
22.86	Single	5U09	Taranabant	5U09-CB₁-Taranabant
22.73	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
22.73	Single	7DW9	Acyclovir triphosphate	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
22.73	Single	7YON	Peptide YY(3-36)	7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
22.73	Consensus	class-d_on	Orthosteric Ligand	ste2_on
22.73	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
22.73	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
22.73	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
22.50	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
22.50	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
22.50	Consensus	class-a_on	Orthosteric Ligand	sensory_on amine_on lipid_on nucleotide_on peptide_on protein_on hcar_on steroid_on melatonin_on
22.50	Consensus	gi_class-a	Orthosteric Ligand	gi_amine gi_lipid gi_melatonin gi_peptide gi_protein gi_nucleotide gi_hcar
22.22	Single	7X9B	Neuropeptide Y	7X9B-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
22.22	Consensus	bombesin_on	Orthosteric Ligand	bb2_on bb1_on
22.22	Consensus	cb1_off	Orthosteric Ligand	5TGZ-CB₁-AM6538 5U09-CB₁-Taranabant
22.22	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
22.00	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/&β;1/&γ;2; RAMP3
22.00	Single	8F0K	Pramlintide analogue san385	8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
21.95	Single	3NY9	PubChem 913103	3NY9-β₂-PubChem 913103
21.95	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2
21.95	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
21.95	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
21.95	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
21.95	Consensus	gi_apelin	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
21.95	Consensus	go_compl-peptide	Orthosteric Ligand	8I95-C3a_B-EP54-Go/&β;1/&γ;2 8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2 8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2
21.95	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on gpr119_on leuko_on lpl_on prostanoid_on
21.74	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
21.74	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on bk1_on
21.74	Consensus	gi_compl-peptide	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2 7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
21.74	Consensus	gs_vasopressin-ot	Orthosteric Ligand	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
21.62	Single	8J18	(3R)-3-hydroxydodecanoic acid	8J18-GPR84-(3R)-3-hydroxydodecanoic acid-Gi1/&β;1/&γ;2
21.57	Consensus	gi_neuropeptide	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2 7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2 7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
21.57	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
21.57	Consensus	npy1_on	Orthosteric Ligand	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
21.57	Consensus	npy_on	Orthosteric Ligand	npy2_on npy4_on npy1_on
21.43	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2
21.43	Consensus	gi_opioid	Orthosteric Ligand	8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 7U2K-μ-C6-guano-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2 8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 7SCG-μ-FH210-Gi1/&β;1/&γ;2 7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2 7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2 7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
21.43	Consensus	go_class-a	Orthosteric Ligand	go_amine go_peptide go_protein
21.28	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
21.28	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2
21.28	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
21.05	Single	5C1M	BU72	5C1M-μ-BU72
21.05	Single	5ZK3	Quinuclidinyl benzilate hydrobromide	5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
21.05	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
21.05	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
21.05	Single	7BB7	Acyclovir triphosphate	7BB7-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
21.05	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/&β;1/&γ;2
21.05	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
21.05	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
21.05	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
21.05	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
21.05	Single	8J19	PubChem 127045422	8J19-GPR84-PubChem 127045422-Gi1/&β;1/&γ;2
21.05	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
21.05	Consensus	a1_on_allo	Orthosteric Ligand	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
21.05	Consensus	cb2_on	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
20.93	Single	6DO1	Angiotensin-Like peptide S1I8	6DO1-AT₁-Angiotensin-Like peptide S1I8
20.93	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/&β;1/&γ;2
20.93	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off alpha1b_off
20.83	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP1
20.83	Single	7VGX	Neuropeptide Y	7VGX-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
20.83	Consensus	gi_chemokine	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2 7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2 7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2 7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2 8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2 6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2 8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
20.75	Single	8F2A	Pramlintide analogue san385	8F2A-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
20.51	Single	2YDV	NECA	2YDV-A_2A-NECA
20.51	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
20.51	Single	5G53	NECA	5G53-A_2A-NECA-Gs
20.51	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
20.51	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/&β;1/&γ;2
20.51	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/&β;1/&γ;2
20.51	Single	7EPE	NAM563	7EPE-mGlu-NAM563
20.51	Single	7EW7	PubChem 4077460	7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
20.51	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/&β;1/&γ;2
20.51	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/&β;1/&γ;2
20.51	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2
20.51	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
20.51	Single	7WV9	PubMed 104895	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
20.51	Single	8E0G	BU72	8E0G-μ-BU72
20.51	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/&β;1/&γ;2
20.51	Single	8JD0	J9R	8JD0-mGlu2; mGlu3-Glutamate-J9R
20.51	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
20.51	Consensus	arrestin2	Orthosteric Ligand	6TKO-β₁-Arformoterol-Arrestin2 6PWC-NTS₁-Neurotensin-Arrestin2 7R0C-V₂-Acyclovir triphosphate-Arrestin2
20.51	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
20.51	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
20.45	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
20.45	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/&β;1/&γ;2
20.45	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
20.45	Consensus	go_peptide	Orthosteric Ligand	go_opioid go_ghrelin go_compl-peptide go_galanin go_vasopressin
20.45	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
20.41	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
20.41	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/&β;1/&γ;2; RAMP1
20.41	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2
20.00	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
20.00	Single	6OS2	TRV026	6OS2-AT₁-TRV026
20.00	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
20.00	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
20.00	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2
20.00	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/&β;1/&γ;2
20.00	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
20.00	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
20.00	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2
20.00	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.00	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2
20.00	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/&β;1/&γ;2
20.00	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
20.00	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/&β;1/&γ;2
20.00	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
20.00	Consensus	adgrg_on	Orthosteric Ligand	adgrg2_on adgrg3_on
20.00	Consensus	cannabinoid_off	Orthosteric Ligand	cb1_off cb2_off
20.00	Consensus	class-b2_on	Orthosteric Ligand	adgrg_on
20.00	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
20.00	Consensus	dp2_off	Orthosteric Ligand	6D27-DP₂-CAY10471 6D26-DP₂-Fevipiprant
20.00	Consensus	dp_off	Orthosteric Ligand	dp2_off
20.00	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_muscarinic gs_tar
20.00	Consensus	mop_on	Orthosteric Ligand	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
20.00	Consensus	s1p_on	Orthosteric Ligand	s1p3_on s1p5_on s1p1_on s1p2_on
19.64	Single	8F2B	Pramlintide analogue san45	8F2B-CT (AMY3)-Pramlintide analogue san45-Gs/&β;1/&γ;2; RAMP3
19.61	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
19.57	Single	7KH0	Acyclovir triphosphate	7KH0-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
19.57	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
19.57	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
19.57	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
19.57	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2
19.57	Consensus	c5a1_on	Orthosteric Ligand	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2 8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
19.57	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
19.57	Consensus	gs_bradykinin	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
19.51	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
19.51	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
19.51	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2
19.51	Single	7EZC	UKA	7EZC-A_2A-UKA
19.51	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
19.51	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
19.51	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/&β;1/&γ;2
19.51	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/&β;1/&γ;2
19.51	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/&β;1/&γ;2
19.51	Single	8WRZ	8D0	8WRZ-CB₁-8D0-Arrestin1
19.51	Single	8XJO	U46619	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
19.51	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
19.51	Consensus	adgrg2_on	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
19.51	Consensus	beta1_off_allo	Orthosteric Ligand	4BVN-β₁-Cyanopindolol-Na
19.51	Consensus	bileacid_on	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
19.51	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
19.51	Consensus	s1p1_on	Orthosteric Ligand	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
19.51	Consensus	steroid_on	Orthosteric Ligand	bileacid_on
19.30	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
19.23	Single	7X9A	Neuropeptide Y	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
19.23	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
19.15	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
19.15	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
19.15	Consensus	bb1_on	Orthosteric Ligand	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
19.15	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
19.15	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
19.05	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
19.05	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
19.05	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
19.05	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/&β;1/&γ;2
19.05	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/&β;1/&γ;2
19.05	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2 8I95-C3a_B-EP54-Go/&β;1/&γ;2
19.05	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
19.05	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
19.05	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_prostanoid gi_ffa gi_lpl gi_leukotriene
19.05	Consensus	go_ghrelin	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
19.05	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
19.05	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
19.05	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
19.05	Consensus	protein_on	Orthosteric Ligand	ccr_on chemokine_on gphr_on chemerin_on
18.92	Single	7T32	ZM241385	7T32-A_2A-ZM241385
18.92	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/&β;1/&γ;2
18.92	Single	8GDZ	Epinephrine	8GDZ-β₂-Epinephrine-Gs/&β;1/&γ;2
18.92	Single	8GGT	Epinephrine	8GGT-β₂-Epinephrine
18.92	Single	8GUR	PubChem 104895	8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2
18.92	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
18.92	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2
18.92	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2
18.75	Single	7F53	Alpha-MSH	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2
18.75	Consensus	ccr_on	Orthosteric Ligand	ccr5_on ccr6_on ccr1_on ccr2_on ccr8_on
18.75	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
18.60	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
18.60	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2
18.60	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2
18.60	Single	8G59	TUG-891	8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
18.60	Single	8GHV	PubChem 145964903	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
18.60	Consensus	fpr-alx_on	Orthosteric Ligand	fpr1-alx_on fpr2-alx_on
18.60	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
18.42	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
18.42	Single	4U16	N-Methyl Scopolamine	4U16-M₃-N-Methyl Scopolamine
18.42	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
18.42	Single	5JQH	(S)-Carazolol	5JQH-β₂-(S)-Carazolol
18.42	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2
18.42	Single	6PS1	Timolol	6PS1-β₂-Timolol
18.42	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/&β;1/&γ;2
18.42	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
18.42	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
18.42	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
18.42	Single	7T2G	Mitragynine pseudoindoxyl	7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2
18.42	Single	7V3Z	PubMed 104895	7V3Z-CB₁-PubMed 104895
18.42	Single	8GEB	Epinephrine	8GEB-β₂-Epinephrine-Gs/&β;1/&γ;2
18.42	Single	8GEH	Epinephrine	8GEH-β₂-Epinephrine-Gs/&β;1/&γ;2
18.42	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/&β;1/&γ;2
18.42	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2
18.42	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
18.42	Consensus	cb1_on_allo	Orthosteric Ligand	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
18.42	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
18.42	Consensus	gi_hca	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
18.42	Consensus	gi_hcar	Orthosteric Ligand	gi_hca
18.42	Consensus	hca2_on	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JHY-HCA₂-Compound 9n-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2 8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
18.37	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
18.37	Single	8FEG	PRD_002517	8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
18.37	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2
18.37	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
18.37	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
18.37	Consensus	gs_endothelin	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
18.18	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
18.18	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
18.18	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/&β;1/&γ;2
18.18	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
18.18	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
18.18	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
18.18	Consensus	sst_off	Orthosteric Ligand	sst2_off
17.95	Single	4WW3	All-trans-retinal	4WW3-Rhodopsin-All-trans-retinal
17.95	Single	5NM2	ZM241385	5NM2-A_2A-ZM241385-Na
17.95	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
17.95	Single	5TVN	LSD	5TVN-5-HT_2B-LSD
17.95	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
17.95	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
17.95	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
17.95	Single	6PS6	Timolol	6PS6-β₂-Timolol
17.95	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
17.95	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/&β;1/&γ;2
17.95	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2
17.95	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2
17.95	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2
17.95	Single	7XKA	Epinephrine	7XKA-β₂-Epinephrine
17.95	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
17.95	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
17.95	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2
17.95	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/&β;1/&γ;2
17.95	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/&β;1/&γ;2
17.95	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/&β;1/&γ;2
17.95	Single	8QOT	Nanobody E	8QOT-μ-Nanobody E
17.95	Single	8UNY	Epinephrine	8UNY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
17.95	Consensus	a2a_on	Orthosteric Ligand	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
17.95	Consensus	adrenergic_off	Orthosteric Ligand	beta_off alpha_off
17.95	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
17.95	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
17.95	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
17.95	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
17.95	Consensus	gs_adrenergic	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2 7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJI-β₃-Solabegron-Gs/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
17.95	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
17.95	Consensus	m2_off	Orthosteric Ligand	5ZKB-M₂-AF-DX 384 5ZKC-M₂-N-Methyl Scopolamine 5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
17.95	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2 8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2 8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
17.78	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
17.78	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
17.78	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1
17.78	Single	7O7F	(6P4)CCL5	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1
17.78	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/&β;1/&γ;2
17.78	Consensus	gs_motilin	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.78	Consensus	gs_tachykinin	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.65	Single	7XKD	Betahydroxyandrosterone	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
17.65	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
17.65	Consensus	melanocortin_on	Orthosteric Ligand	mc2_on mc1_on mc3_on mc4_on mc5_on
17.50	Single	3P0G	BI167107	3P0G-β₂-BI167107
17.50	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/&β;1/&γ;2
17.50	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
17.50	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
17.50	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
17.50	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
17.50	Single	5V54	Methiothepin	5V54-5-HT_1B-Methiothepin
17.50	Single	5XR8	AM841	5XR8-CB₁-AM841
17.50	Single	5XRA	AM11542	5XRA-CB₁-AM11542
17.50	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
17.50	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
17.50	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
17.50	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
17.50	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
17.50	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
17.50	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
17.50	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2
17.50	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/&β;1/&γ;2
17.50	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2
17.50	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/&β;1/&γ;2
17.50	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
17.50	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2
17.50	Single	8ID6	Oleic acid	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2
17.50	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2
17.50	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2
17.50	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/&β;1/&γ;2
17.50	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/&β;1/&γ;2
17.50	Consensus	5ht1_off	Orthosteric Ligand	5ht1b_off
17.50	Consensus	5ht1b_off	Orthosteric Ligand	5V54-5-HT_1B-Methiothepin
17.50	Consensus	5ht1b_on	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
17.50	Consensus	5ht_off	Orthosteric Ligand	5ht2_off 5ht5_off 5ht1_off
17.50	Consensus	a2_on	Orthosteric Ligand	a2a_on a2b_on
17.50	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
17.50	Consensus	class-a_off	Orthosteric Ligand	sensory_off amine_off lipid_off nucleotide_off peptide_off protein_off hcar_off
17.50	Consensus	dopamine_off	Orthosteric Ligand	d3_off d2_off d4_off
17.50	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_adrenergic gi_dopamine gi_muscarinic gi_histamine
17.50	Consensus	gi_dopamine	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
17.50	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2
17.50	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-Methyl Scopolamine 5ZHP-M₃-PubChem 134828589
17.50	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
17.39	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
17.39	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
17.39	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
17.39	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
17.39	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
17.39	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2
17.39	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/&β;1/&γ;2
17.39	Consensus	bk2_on	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
17.39	Consensus	ccr1_on	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
17.39	Consensus	ghrelin_on	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
17.14	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
17.07	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
17.07	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
17.07	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
17.07	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
17.07	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
17.07	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
17.07	Single	6KQI	PubMed 104895	6KQI-CB₁-PubMed 104895-ORG27569
17.07	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
17.07	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
17.07	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
17.07	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
17.07	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
17.07	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2
17.07	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
17.07	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2
17.07	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2
17.07	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2
17.07	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
17.07	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
17.07	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2
17.07	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2
17.07	Single	8IBU	Erythromycin A	8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.07	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
17.07	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
17.07	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
17.07	Single	8JWY	PubChem 168451710	8JWY-A_2A-PubChem 168451710
17.07	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
17.07	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/&β;1/&γ;2
17.07	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2
17.07	Single	8WU1	KCA	8WU1-CB₁-KCA-Arrestin1
17.07	Consensus	cb1_off_allo	Orthosteric Ligand	6KQI-CB₁-PubMed 104895-ORG27569
17.07	Consensus	gi_prostanoid	Orthosteric Ligand	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2 8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
17.07	Consensus	go_5ht	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2 7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
17.07	Consensus	gs_bileacid	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
17.07	Consensus	gs_steroid	Orthosteric Ligand	gs_bileacid
17.07	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z34-LPA₁-ONO-9780307 4Z35-LPA₁-ONO-9910539 7YU4-LPA₁-ONO-0740556
17.07	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
17.07	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
17.07	Consensus	opioid_off	Orthosteric Ligand	kop_off mop_off nop_off dop_off
17.02	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2
17.02	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
17.02	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/&β;1/&γ;2
17.02	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
17.02	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
17.02	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
17.02	Consensus	gs_ghrelin	Orthosteric Ligand	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.67	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
16.67	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
16.67	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
16.67	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
16.67	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
16.67	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
16.67	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
16.67	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
16.67	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/&β;1/&γ;2
16.67	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
16.67	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
16.67	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2
16.67	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2
16.67	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2
16.67	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
16.67	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
16.67	Single	7P00	Substance P	7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.67	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
16.67	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
16.67	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
16.67	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.67	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2
16.67	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/&β;1/&γ;2
16.67	Single	7XKF	Betahydroxyandrosterone	7XKF-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
16.67	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/&β;1/&γ;2
16.67	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
16.67	Single	8DPF	Lorcaserin	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
16.67	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2
16.67	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
16.67	Single	8GAG	YVF	8GAG-CB₁-YVF-Gi1/&β;1/&γ;2
16.67	Single	8GGC	Epinephrine	8GGC-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
16.67	Single	8GGE	Epinephrine	8GGE-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
16.67	Single	8GGS	Epinephrine	8GGS-β₂-Epinephrine
16.67	Single	8GH1	Epinephrine	8GH1-β₂-Epinephrine
16.67	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2
16.67	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2
16.67	Single	8ID8	TUG-891	8ID8-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
16.67	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.67	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/&β;1/&γ;2
16.67	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
16.67	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2
16.67	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/&β;1/&γ;2
16.67	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
16.67	Single	8UNV	Epinephrine	8UNV-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
16.67	Consensus	5ht5a_off	Orthosteric Ligand	7UM4-5-HT_5A-AS2674723
16.67	Consensus	cckb_on	Orthosteric Ligand	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
16.67	Consensus	endothelin_off	Orthosteric Ligand	etb_off
16.67	Consensus	ep4_on	Orthosteric Ligand	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2
16.67	Consensus	etb_off	Orthosteric Ligand	5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500 5X93-ET_B-K-8794
16.67	Consensus	fpa_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.67	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
16.67	Consensus	gi_neuromedin	Orthosteric Ligand	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
16.67	Consensus	gs_galanin	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
16.67	Consensus	gs_lipid	Orthosteric Ligand	gs_ffa gs_prostanoid
16.67	Consensus	gs_orexin	Orthosteric Ligand	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
16.67	Consensus	gs_prostanoid	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2 7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.67	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
16.67	Consensus	orexin_on	Orthosteric Ligand	ox2_on
16.33	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
16.33	Consensus	ccr8_on	Orthosteric Ligand	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
16.33	Consensus	etb_on	Orthosteric Ligand	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
16.28	Single	6PT3	DPI-287	6PT3-δ-DPI-287
16.28	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.28	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
16.28	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/&β;1/&γ;2
16.28	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
16.28	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
16.28	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.28	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.28	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2
16.28	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
16.28	Consensus	chemokine_on	Orthosteric Ligand	cxcr_on cx3cr_on
16.28	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
16.28	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2 7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
16.28	Consensus	gs_bombesin	Orthosteric Ligand	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.28	Consensus	motilin_on	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.28	Consensus	nk1_on	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.28	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
16.22	Single	3VGA	ZM241385	3VGA-A_2A-ZM241385-Antibody
16.22	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
16.22	Single	5K2D	ZM241385	5K2D-A_2A-ZM241385
16.22	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
16.22	Single	6AKX	A4R	6AKX-CCR5-A4R
16.22	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
16.22	Single	6JZH	ZM241385	6JZH-A_2A-ZM241385-Na
16.22	Single	6OBA	(S)-Alprenolol	6OBA-β₂-(S)-Alprenolol-GTPL11074
16.22	Single	6PS7	ZM241385	6PS7-A_2A-ZM241385-Na
16.22	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
16.22	Single	7EJ0	L-Norepinephrine	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2
16.22	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
16.22	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
16.22	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/&β;1/&γ;2
16.22	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/&β;1/&γ;2
16.22	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
16.22	Single	7YMH	Norepinephrine	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2
16.22	Single	8GEC	Epinephrine	8GEC-β₂-Epinephrine-Gs/&β;1/&γ;2
16.22	Single	8GEF	Epinephrine	8GEF-β₂-Epinephrine-Gs/&β;1/&γ;2
16.22	Single	8GG7	Epinephrine	8GG7-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
16.22	Single	8GGA	Epinephrine	8GGA-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
16.22	Single	8GGF	Epinephrine	8GGF-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
16.22	Single	8GGV	Epinephrine	8GGV-β₂-Epinephrine
16.22	Single	8GGX	Epinephrine	8GGX-β₂-Epinephrine
16.22	Single	8GH0	Epinephrine	8GH0-β₂-Epinephrine
16.22	Single	8HMP	PubChem 69921479	8HMP-GPR52-PubChem 69921479-Gs/&β;1/&γ;2
16.22	Single	8IW4	Spermidine	8IW4-TAAR9-Spermidine-chim(NtGi1-Gs)/&β;1/&γ;2
16.22	Single	8IWE	Spermidine	8IWE-TAAR9-Spermidine
16.22	Single	8UNO	Epinephrine	8UNO-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
16.22	Single	8UO1	Epinephrine	8UO1-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
16.22	Single	8UO3	Epinephrine	8UO3-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
16.22	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
16.22	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
16.22	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
16.22	Consensus	5ht2_on	Orthosteric Ligand	5ht2a_on 5ht2c_on
16.22	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
16.22	Consensus	beta2_off_allo	Orthosteric Ligand	6OBA-β₂-(S)-Alprenolol-GTPL11074
16.22	Consensus	gi_nucleotide	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
16.22	Consensus	mglu_on	Other Ligand	mglu2_on mglu4_on
15.91	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
15.91	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
15.91	Single	5VBL	Apelin Mimetic Peptide Agonist	5VBL-Apelin-Apelin Mimetic Peptide Agonist
15.91	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
15.91	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
15.91	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
15.91	Single	7RMH	Substance P	7RMH-NK₁-Substance P-Gs/&β;1/&γ;2
15.91	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
15.91	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
15.91	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
15.91	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
15.91	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/&β;1/&γ;2
15.91	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin 8HN1-Alpha1A-Toxin AdTx1
15.91	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
15.91	Consensus	protein_off	Orthosteric Ligand	ccr_off chemokine_off gnrh_off
15.91	Consensus	sst_on	Orthosteric Ligand	sst2_on sst4_on
15.91	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
15.79	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
15.79	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
15.79	Single	4LDO	L-Epinephrine	4LDO-β₂-L-Epinephrine
15.79	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
15.79	Single	5IU4	ZM241385	5IU4-A_2A-ZM241385-Na
15.79	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
15.79	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
15.79	Single	5JTB	ZM241385	5JTB-A_2A-ZM241385
15.79	Single	5K2B	ZM241385	5K2B-A_2A-ZM241385-Na
15.79	Single	5K2C	ZM241385	5K2C-A_2A-ZM241385-Na
15.79	Single	5NLX	ZM241385	5NLX-A_2A-ZM241385-Na
15.79	Single	5NM4	ZM241385	5NM4-A_2A-ZM241385-Na
15.79	Single	6PS4	ICI 118-551	6PS4-β₂-ICI 118-551
15.79	Single	6PS5	(S)-Propranolol	6PS5-β₂-(S)-Propranolol
15.79	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
15.79	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
15.79	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
15.79	Single	7BB6	Acyclovir triphosphate	7BB6-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
15.79	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/&β;1/&γ;2
15.79	Single	7DHI	Salbutamol	7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
15.79	Single	7F61	PF-03654746	7F61-H₃-PF-03654746-Cholesterol
15.79	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
15.79	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
15.79	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
15.79	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
15.79	Single	8GE1	Epinephrine	8GE1-β₂-Epinephrine-Gs/&β;1/&γ;2
15.79	Single	8GE4	Epinephrine	8GE4-β₂-Epinephrine-Gs/&β;1/&γ;2
15.79	Single	8GE6	Epinephrine	8GE6-β₂-Epinephrine-Gs/&β;1/&γ;2
15.79	Single	8GE7	Epinephrine	8GE7-β₂-Epinephrine-Gs/&β;1/&γ;2
15.79	Single	8GE8	Epinephrine	8GE8-β₂-Epinephrine-Gs/&β;1/&γ;2
15.79	Single	8GE9	Epinephrine	8GE9-β₂-Epinephrine-Gs/&β;1/&γ;2
15.79	Single	8GEG	Epinephrine	8GEG-β₂-Epinephrine-Gs/&β;1/&γ;2
15.79	Single	8GFV	Epinephrine	8GFV-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
15.79	Single	8GG4	Epinephrine	8GG4-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
15.79	Single	8GG8	Epinephrine	8GG8-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
15.79	Single	8GGI	Epinephrine	8GGI-β₂-Epinephrine
15.79	Single	8GGK	Epinephrine	8GGK-β₂-Epinephrine
15.79	Single	8GGL	Epinephrine	8GGL-β₂-Epinephrine
15.79	Single	8GGM	Epinephrine	8GGM-β₂-Epinephrine
15.79	Single	8GGP	Epinephrine	8GGP-β₂-Epinephrine
15.79	Single	8GGQ	Epinephrine	8GGQ-β₂-Epinephrine
15.79	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2
15.79	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/&β;1/&γ;2
15.79	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/&β;1/&γ;2
15.79	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2
15.79	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/&β;1/&γ;2
15.79	Single	8JLN	T1AM	8JLN-TA1-T1AM-Gs/&β;1/&γ;2
15.79	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
15.79	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/&β;1/&γ;2
15.79	Single	8UNQ	Epinephrine	8UNQ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
15.79	Single	8UNZ	Epinephrine	8UNZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
15.79	Single	8UO2	Epinephrine	8UO2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
15.79	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
15.79	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6WH4-5-HT_2A-Methiothepin 7VOE-5-HT_2A-Aripiprazole 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 6A93-5-HT_2A-Risperidone
15.79	Consensus	5ht2a_on	Orthosteric Ligand	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
15.79	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
15.79	Consensus	gnrh_off	Orthosteric Ligand	gnrh1_off
15.79	Consensus	gs_tar	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2 8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
15.79	Consensus	h3_on_allo	Orthosteric Ligand	7F61-H₃-PF-03654746-Cholesterol
15.79	Consensus	hca_on	Orthosteric Ligand	hca2_on hca3_on
15.79	Consensus	hcar_on	Orthosteric Ligand	hca_on
15.79	Consensus	lh_on_allo	Other Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
15.79	Consensus	m1_off_allo	Orthosteric Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
15.79	Consensus	s1p1_off	Orthosteric Ligand	3V2Y-S1P₁-PubChem 51892645
15.79	Consensus	s1p_off	Orthosteric Ligand	s1p1_off
15.56	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
15.56	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
15.56	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
15.56	Single	7RMI	Substance P	7RMI-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
15.56	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
15.56	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2
15.56	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
15.38	Single	2Y04	Salbutamol	2Y04-β₁-Salbutamol
15.38	Single	3EML	ZM241385	3EML-A_2A-ZM241385
15.38	Single	3NY8	ICI 118-551	3NY8-β₂-ICI 118-551
15.38	Single	3NYA	(S)-Alprenolol	3NYA-β₂-(S)-Alprenolol
15.38	Single	3ZPQ	4-(piperazin-1- yl)-1H-indole	3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na
15.38	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
15.38	Single	4EIY	ZM241385	4EIY-A_2A-ZM241385-Na
15.38	Single	4GBR	(S)-Carazolol	4GBR-β₂-(S)-Carazolol
15.38	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
15.38	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
15.38	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
15.38	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
15.38	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
15.38	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
15.38	Single	5K2A	ZM241385	5K2A-A_2A-ZM241385-Na
15.38	Single	5OLG	ZM241385	5OLG-A_2A-ZM241385-Na
15.38	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
15.38	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
15.38	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
15.38	Single	5UEN	DU172	5UEN-A₁-DU172
15.38	Single	5VRA	ZM241385	5VRA-A_2A-ZM241385-Na
15.38	Single	5YC8	N-Methyl Scopolamine	5YC8-M₂-N-Methyl Scopolamine
15.38	Single	5ZK8	N-Methyl Scopolamine	5ZK8-M₂-N-Methyl Scopolamine
15.38	Single	5ZKC	N-Methyl Scopolamine	5ZKC-M₂-N-Methyl Scopolamine
15.38	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
15.38	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
15.38	Single	6H7M	Salbutamol	6H7M-β₁-Salbutamol
15.38	Single	6LPJ	ZM241385	6LPJ-A_2A-ZM241385-Na
15.38	Single	6LPK	ZM241385	6LPK-A_2A-ZM241385-Na
15.38	Single	6PS0	(S)-Carazolol	6PS0-β₂-(S)-Carazolol
15.38	Single	6PS2	(S)-Alprenolol	6PS2-β₂-(S)-Alprenolol
15.38	Single	6S0L	ZM241385	6S0L-A_2A-ZM241385
15.38	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
15.38	Single	7BTS	L-Epinephrine	7BTS-β₁-L-Epinephrine
15.38	Single	7BU6	L-Norepinephrine	7BU6-β₁-L-Norepinephrine
15.38	Single	7CFM	P395	7CFM-GPBA-P395-Gs/&β;1/&γ;2
15.38	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
15.38	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/&β;1/&γ;2
15.38	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
15.38	Single	7LJC	PubChem 86764103	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2
15.38	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
15.38	Single	7S0G	Isoprenaline	7S0G-β₁-Isoprenaline-chim(Gi1-CtGs)/&β;1/&γ;2
15.38	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
15.38	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
15.38	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/&β;1/&γ;2
15.38	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
15.38	Single	7UM5	5-CT	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2
15.38	Single	7UM6	Lisuride	7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2
15.38	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/&β;1/&γ;2
15.38	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/&β;1/&γ;2
15.38	Single	7WC7	Lisuride	7WC7-5-HT_2A-Lisuride
15.38	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
15.38	Single	7XJH	Isoproterenol	7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
15.38	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
15.38	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2
15.38	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
15.38	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
15.38	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
15.38	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
15.38	Single	8GE3	Epinephrine	8GE3-β₂-Epinephrine-Gs/&β;1/&γ;2
15.38	Single	8GEE	Epinephrine	8GEE-β₂-Epinephrine-Gs/&β;1/&γ;2
15.38	Single	8GFW	Epinephrine	8GFW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
15.38	Single	8GFX	Epinephrine	8GFX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
15.38	Single	8GFY	Epinephrine	8GFY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
15.38	Single	8GFZ	Epinephrine	8GFZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
15.38	Single	8GG0	Epinephrine	8GG0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
15.38	Single	8GG1	Epinephrine	8GG1-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
15.38	Single	8GG2	Epinephrine	8GG2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
15.38	Single	8GG6	Epinephrine	8GG6-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
15.38	Single	8GGB	Epinephrine	8GGB-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
15.38	Single	8GGJ	Epinephrine	8GGJ-β₂-Epinephrine
15.38	Single	8GGN	Epinephrine	8GGN-β₂-Epinephrine
15.38	Single	8GGO	Epinephrine	8GGO-β₂-Epinephrine
15.38	Single	8GGU	Epinephrine	8GGU-β₂-Epinephrine
15.38	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
15.38	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/&β;1/&γ;2
15.38	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
15.38	Single	8JJO	Alprenolol	8JJO-β₂-Alprenolol
15.38	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
15.38	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
15.38	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
15.38	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
15.38	Single	8UNM	Epinephrine	8UNM-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
15.38	Single	8UNN	Epinephrine	8UNN-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
15.38	Single	8UNP	Epinephrine	8UNP-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
15.38	Single	8UO4	Epinephrine	8UO4-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
15.38	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2
15.38	Single	8X17	Namodenoson	8X17-A3A-Namodenoson-Gi1/&β;1/&γ;2
15.38	Single	8X63	Mepyramine	8X63-H₁-Mepyramine
15.38	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-alpha-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
15.38	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
15.38	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
15.38	Consensus	a2_off	Orthosteric Ligand	a2a_off
15.38	Consensus	a2a_off	Orthosteric Ligand	8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 5UIG-A_2A-J3.651.884G 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-PubChem 168451710 5K2D-A_2A-ZM241385
15.38	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on
15.38	Consensus	adrenergic_on	Orthosteric Ligand	beta_on alpha_on
15.38	Consensus	amine_on	Orthosteric Ligand	adrenergic_on histamine_on muscarinic_on tar_on 5ht_on dopamine_on
15.38	Consensus	dopamine_on	Orthosteric Ligand	d3_on d2_on d5_on d1_on
15.38	Consensus	fsh_on_allo	Other Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
15.38	Consensus	go_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
15.38	Consensus	histamine_on	Orthosteric Ligand	h1_on h4_on
15.38	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off leuko_off lpl_off paf_off prostanoid_off
15.38	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
15.38	Consensus	m4_on_allo	Orthosteric Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
15.38	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
15.38	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on
15.38	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491 5ZKP-PAF-Foropafant (SR27417)
15.38	Consensus	smo_off	Orthosteric Ligand	5L7I-SMO-Vismodegib 4O9R-SMO-Cyclopamine 4QIM-SMO-PubChem 24905375 4JKV-SMO-Taladegib (LY2940680)
15.38	Consensus	tar_on	Orthosteric Ligand	ta1_on
15.22	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
15.22	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
15.22	Single	7F4D	Alpha-MSH	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2
15.22	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
15.22	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2
15.22	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/&β;1/&γ;2
15.22	Consensus	ccr_off	Orthosteric Ligand	ccr5_off ccr8_off
15.22	Consensus	cx3cr1_on	Orthosteric Ligand	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
15.22	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on
15.09	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
15.00	Single	2RH1	(S)-Carazolol	2RH1-β₂-(S)-Carazolol
15.00	Single	2Y03	Isoprenaline	2Y03-β₁-Isoprenaline
15.00	Single	2YCW	(S)-Carazolol	2YCW-β₁-(S)-Carazolol
15.00	Single	4JKV	Taladegib (LY2940680)	4JKV-SMO-Taladegib (LY2940680)
15.00	Single	5D6L	(S)-Carazolol	5D6L-β₂-(S)-Carazolol
15.00	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
15.00	Single	5N2R	PubChem 92460631; psb36	5N2R-A_2A-PubChem 92460631; psb36-Na
15.00	Single	5N2S	PSB36	5N2S-A₁-PSB36
15.00	Single	5WIU	Nemonapride	5WIU-D₄-Nemonapride
15.00	Single	5WIV	Nemonapride	5WIV-D₄-Nemonapride-Na
15.00	Single	5X7D	(S)-Carazolol	5X7D-β₂-(S)-Carazolol-PubChem 129318963
15.00	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
15.00	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/&β;1/&γ;2
15.00	Single	6E67	BI167107	6E67-β₂-BI167107-Gs (fused)
15.00	Single	6KUW	PubChem 57213234	6KUW-α_2c-PubChem 57213234
15.00	Single	6LPL	ZM241385	6LPL-A_2A-ZM241385-Na
15.00	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
15.00	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
15.00	Single	6PS3	(S)-Carvedilol	6PS3-β₂-(S)-Carvedilol
15.00	Single	6S0Q	ZM241385	6S0Q-A_2A-ZM241385
15.00	Single	6WQA	ZM241385	6WQA-A_2A-ZM241385-Na
15.00	Single	7BVQ	(S)-Carazolol	7BVQ-β₁-(S)-Carazolol
15.00	Single	7C4S	S1P	7C4S-S1P₃-S1P
15.00	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2
15.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
15.00	Single	7RM5	ZM241385	7RM5-A_2A-ZM241385-Na
15.00	Single	7S0F	Isoprenaline	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2
15.00	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/&β;1/&γ;2
15.00	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
15.00	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/&β;1/&γ;2
15.00	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
15.00	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
15.00	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
15.00	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/&β;1/&γ;2
15.00	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2
15.00	Single	8F0J	Pramlintide analogue san45	8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2
15.00	Single	8FN1	Neurotensin/neuromedin N	8FN1-NTS₁-Neurotensin/neuromedin N-chim(NtGi1-Go)/&β;1/&γ;2
15.00	Single	8FYN	ZM241385	8FYN-A_2A-ZM241385-Na
15.00	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2
15.00	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/&β;1/&γ;2
15.00	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
15.00	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
15.00	Single	8JPC	Neurotensin 8-13	8JPC-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
15.00	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
15.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
15.00	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
15.00	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide 6DRX-5-HT_2B-Lisuride
15.00	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
15.00	Consensus	alpha2c_off	Orthosteric Ligand	6KUW-α_2c-PubChem 57213234
15.00	Consensus	amine_off	Orthosteric Ligand	adrenergic_off histamine_off muscarinic_off 5ht_off dopamine_off
15.00	Consensus	beta2_off	Orthosteric Ligand	6PS2-β₂-(S)-Alprenolol 6PS3-β₂-(S)-Carvedilol 6PS5-β₂-(S)-Propranolol 6PS6-β₂-Timolol 2RH1-β₂-(S)-Carazolol 6PS4-β₂-ICI 118-551 3NY9-β₂-PubChem 913103
15.00	Consensus	beta2_on	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
15.00	Consensus	beta_off	Orthosteric Ligand	beta1_off beta2_off
15.00	Consensus	beta_on	Orthosteric Ligand	beta1_on beta2_on beta3_on
15.00	Consensus	d4_off	Orthosteric Ligand	5WIU-D₄-Nemonapride
15.00	Consensus	d4_off_allo	Orthosteric Ligand	5WIV-D₄-Nemonapride-Na
15.00	Consensus	gi_adrenergic	Orthosteric Ligand	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2 6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
15.00	Consensus	go_opioid	Orthosteric Ligand	8DZQ-κ-momSalB-Go/&β;1/&γ;2
15.00	Consensus	gs_muscarinic	Orthosteric Ligand	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
15.00	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
14.89	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
14.89	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
14.89	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/&β;1/&γ;2
14.89	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/&β;1/&γ;2
14.89	Consensus	gi_somatostatin	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XMT-SST4-J-2156-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
14.89	Consensus	nmur2_on	Orthosteric Ligand	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
14.71	Single	8GEJ	Epinephrine	8GEJ-β₂-Epinephrine-Gs/&β;1/&γ;2
14.63	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
14.63	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
14.63	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
14.63	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
14.63	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
14.63	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
14.63	Single	5D5A	(S)-Carazolol	5D5A-β₂-(S)-Carazolol
14.63	Single	5D5B	(S)-Carazolol	5D5B-β₂-(S)-Carazolol
14.63	Single	5V56	TC114	5V56-SMO-TC114
14.63	Single	5V57	TC114	5V57-SMO-TC114
14.63	Single	5X93	K-8794	5X93-ET_B-K-8794
14.63	Single	6H7J	Isoprenaline	6H7J-β₁-Isoprenaline
14.63	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
14.63	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
14.63	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
14.63	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
14.63	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
14.63	Single	6OS1	TRV026	6OS1-AT₁-TRV026
14.63	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
14.63	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
14.63	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2
14.63	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
14.63	Single	7FEE	PubMed 104895	7FEE-CB₁-PubMed 104895-ZCZ011
14.63	Single	7JJO	Isoprenaline	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2
14.63	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
14.63	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
14.63	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/&β;1/&γ;2
14.63	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2
14.63	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2
14.63	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2
14.63	Single	7W6P	W96	7W6P-α_2a-W96-Go/&β;1/&γ;2
14.63	Single	7W7E	W58	7W7E-α_2a-W58-Go/&β;1/&γ;2
14.63	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
14.63	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
14.63	Single	7XOX	Cholecystokinin-8	7XOX-CCK_B-Cholecystokinin-8-Gq/&β;1/&γ;2
14.63	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/&β;1/&γ;2
14.63	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
14.63	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/&β;1/&γ;2
14.63	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2
14.63	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2
14.63	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
14.63	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
14.63	Single	8IRR	Rotigotine	8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2
14.63	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
14.63	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/&β;1/&γ;2
14.63	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
14.63	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
14.63	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2
14.63	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/&β;1/&γ;2
14.63	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/&β;1/&γ;2
14.63	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/&β;1/&γ;2
14.63	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
14.63	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
14.63	Single	8X16	Piclidenoson	8X16-A3A-Piclidenoson-Gi1/&β;1/&γ;2
14.63	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
14.63	Consensus	5ht5_off	Orthosteric Ligand	5ht5a_off
14.63	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
14.63	Consensus	alpha1b_off	Orthosteric Ligand	7B6W-α_1b-Cyclazosin
14.63	Consensus	angiotensin_off	Orthosteric Ligand	at1_off at2_off
14.63	Consensus	beta1_off	Orthosteric Ligand	2VT4-β₁-Cyanopindolol 2YCZ-β₁-Iodocyanopindolol
14.63	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
14.63	Consensus	cml1_on	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
14.63	Consensus	ffa4_on	Orthosteric Ligand	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
14.63	Consensus	gi_muscarinic	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
14.63	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 6GDG-A_2A-NECA-Gs/&β;1/&γ;1 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
14.63	Consensus	gs_compl-peptide	Orthosteric Ligand	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
14.63	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
14.63	Consensus	h1_off	Orthosteric Ligand	3RZE-H₁-Cidoxepin 8X5Y-H₁-Astemizole 8X63-H₁-Mepyramine 8X64-H₁-Desloratadine
14.63	Consensus	histamine_off	Orthosteric Ligand	h1_off
14.63	Consensus	lpa1_on	Orthosteric Ligand	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
14.63	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
14.63	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
14.63	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
14.63	Consensus	mglu2_on	Other Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
14.63	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
14.63	Consensus	npy_off	Orthosteric Ligand	npy2_off npy1_off
14.63	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
14.63	Consensus	s1p2_on	Orthosteric Ligand	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
14.58	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
14.58	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
14.58	Consensus	gs_melanocortin	Orthosteric Ligand	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2 7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2
14.29	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
14.29	Single	3D4S	Timolol Maleate	3D4S-β₂-Timolol Maleate
14.29	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
14.29	Single	4GRV	Neurotensin 8-13	4GRV-NTS₁-Neurotensin 8-13
14.29	Single	4LDE	BI167107	4LDE-β₂-BI167107
14.29	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
14.29	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
14.29	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
14.29	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
14.29	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
14.29	Single	6H7N	(S)-Xamoterol	6H7N-β₁-(S)-Xamoterol
14.29	Single	6H7O	Cyanopindolol	6H7O-β₁-Cyanopindolol
14.29	Single	6IIU	Ramatroban	6IIU-TP-Ramatroban
14.29	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
14.29	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/&β;1/&γ;2
14.29	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
14.29	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
14.29	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
14.29	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
14.29	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/&β;1/γ1
14.29	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
14.29	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
14.29	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
14.29	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
14.29	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/&β;1/&γ;2
14.29	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
14.29	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
14.29	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
14.29	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2
14.29	Single	8I95	EP54	8I95-C3a_B-EP54-Go/&β;1/&γ;2
14.29	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
14.29	Single	8JPB	Neurotensin 8-13	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
14.29	Single	8T3Q	DHA	8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
14.29	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
14.29	Consensus	at2_off	Orthosteric Ligand	7JNI-AT₂-Olodanrigan
14.29	Consensus	beta1_on	Orthosteric Ligand	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
14.29	Consensus	blt1_off	Orthosteric Ligand	7K15-BLT₁-MKD046-Na
14.29	Consensus	blt_off	Orthosteric Ligand	blt1_off
14.29	Consensus	ep_on	Orthosteric Ligand	ep4_on ep2_on ep3_on
14.29	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
14.29	Consensus	hca2_on_allo	Orthosteric Ligand	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2 8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
14.29	Consensus	leuko_off	Orthosteric Ligand	blt_off cyslt_off
14.29	Consensus	nts1_on	Orthosteric Ligand	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
14.29	Consensus	nts_on	Orthosteric Ligand	nts1_on
14.29	Consensus	peptide_off	Orthosteric Ligand	opioid_off angiotensin_off bombesin_off cck_off endothelin_off ghrelin_off npy_off nts_off orexin_off vasopressin-ot_off tachykinin_off sst_off
14.29	Consensus	prostanoid_on	Orthosteric Ligand	ep_on fpa_on
14.29	Consensus	tsh_on_allo	Other Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
14.00	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
13.95	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
13.95	Single	5CGD	HTL14242	5CGD-mGlu₅-HTL14242
13.95	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
13.95	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
13.95	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
13.95	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2
13.95	Single	8E9Y	PubChem 446603	8E9Y-M₃-PubChem 446603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
13.95	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
13.95	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
13.95	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
13.95	Consensus	c5a1_off_ortoallo	Orthosteric Ligand	6C1Q-C5a₁-PMX53-NDT9513727 6C1R-C5a₁-PMX53-Avacopan; Na
13.95	Consensus	gi_neurotensin	Orthosteric Ligand	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1 6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
13.95	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
13.89	Single	6LI0	GTPL9804	6LI0-GPR52-GTPL9804
13.89	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2
13.89	Single	8DPI	Lorcaserin	8DPI-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
13.89	Single	8GGR	Epinephrine	8GGR-β₂-Epinephrine
13.89	Single	8IW7	2-Phenylethylamine	8IW7-TAAR9-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
13.89	Single	8J6Q	Beta-hydroxybutyrate	8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
13.89	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
13.89	Single	8WC9	ZH8651	8WC9-TA1-ZH8651-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
13.64	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
13.64	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
13.64	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/&β;1/&γ;2
13.64	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
13.64	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2
13.64	Single	7RMG	Substance P	7RMG-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
13.64	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
13.64	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/&β;1/&γ;2
13.64	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2
13.64	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/&β;1/&γ;2
13.64	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/&β;1/&γ;2
13.64	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
13.64	Consensus	mc4_on	Orthosteric Ligand	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
13.51	Single	3AYM	All-trans-retinal	3AYM-Rhodopsin-All-trans-retinal
13.51	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
13.51	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
13.51	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
13.51	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
13.51	Single	7EJK	Oxymetazoline	7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2
13.51	Single	7V68	Iperoxo	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
13.51	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2
13.51	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
13.51	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
13.51	Single	7YS6	Serotonin	7YS6-5-HT₆-Serotonin-chim(NtGi1-Gs)/&β;1/&γ;2
13.51	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/&β;1/&γ;2
13.51	Single	8GEI	Epinephrine	8GEI-β₂-Epinephrine-Gs/&β;1/&γ;2
13.51	Single	8GGY	Epinephrine	8GGY-β₂-Epinephrine
13.51	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/&β;1/&γ;2
13.51	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/&β;1/&γ;2
13.51	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2
13.51	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
13.51	Single	8UNX	Epinephrine	8UNX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
13.51	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2
13.51	Single	8WC3	SEP-363856	8WC3-TA1-SEP-363856-chim(NtGi1-Gs)/&β;1/&γ;2
13.51	Consensus	5ht4_on	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
13.51	Consensus	go_adhesion	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
13.51	Consensus	go_class-b2	Orthosteric Ligand	go_adhesion
13.46	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/&β;1/&γ;2
13.33	Single	4AMJ	(S)-Carvedilol	4AMJ-β₁-(S)-Carvedilol
13.33	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
13.33	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
13.33	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/&β;1/&γ;2
13.33	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
13.33	Consensus	sst2_on	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
13.16	Single	2X72	All-trans-retinal	2X72-Rhodopsin-All-trans-retinal-Gt(CT)
13.16	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
13.16	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
13.16	Single	3VG9	ZM241385	3VG9-A_2A-ZM241385-Antibody
13.16	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
13.16	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
13.16	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
13.16	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/&β;1/&γ;2
13.16	Single	6KUX	RS-79948	6KUX-α_2a-RS-79948
13.16	Single	6KUY	PubChem 145704643	6KUY-α_2a-PubChem 145704643
13.16	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
13.16	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
13.16	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
13.16	Single	7DHR	Isoprenaline	7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2
13.16	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/&β;1/&γ;2
13.16	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
13.16	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
13.16	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
13.16	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
13.16	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/&β;1/&γ;2
13.16	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
13.16	Single	7X5H	5-CT	7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2
13.16	Single	7YM8	Oxymetazoline	7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2
13.16	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
13.16	Single	8EFO	PZM21	8EFO-μ-PZM21-Gi1/&β;1/&γ;2
13.16	Single	8GEA	Epinephrine	8GEA-β₂-Epinephrine-Gs/&β;1/&γ;2
13.16	Single	8GED	Epinephrine	8GED-β₂-Epinephrine-Gs/&β;1/&γ;2
13.16	Single	8GG9	Epinephrine	8GG9-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
13.16	Single	8GGW	Epinephrine	8GGW-β₂-Epinephrine
13.16	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
13.16	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2
13.16	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/&β;1/&γ;2
13.16	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2
13.16	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/&β;1/&γ;2
13.16	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
13.16	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/&β;1/&γ;2
13.16	Single	8UNL	Epinephrine	8UNL-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
13.16	Single	8UNT	Epinephrine	8UNT-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
13.16	Single	8UNU	Epinephrine	8UNU-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
13.16	Single	8UNW	Epinephrine	8UNW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
13.16	Single	8UO0	Epinephrine	8UO0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
13.16	Consensus	5ht2c_on	Orthosteric Ligand	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
13.16	Consensus	5ht_on	Orthosteric Ligand	5ht1_on 5ht2_on 5ht4_on 5ht5_on 5ht6_on 5ht7_on
13.16	Consensus	a2a_off_allo	Orthosteric Ligand	6ZDR-A_2A-HMS1413f12-Na 6GT3-A_2A-Imaradenant-Na 8CU7-A_2A-LJ-4517-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PubChem 92460631; psb36-Na 5MZJ-A_2A-Theophylline-Na 5OLO-A_2A-Tozadenant-Na 5OLH-A_2A-Vipadenant-Na 5NM4-A_2A-ZM241385-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5MZP-A_2A-Caffeine-Na 8CIC-A_2A-Etrumadenant-Na
13.16	Consensus	alpha1_on	Orthosteric Ligand	alpha1a_on
13.16	Consensus	alpha1a_on	Orthosteric Ligand	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2 7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
13.16	Consensus	alpha2_off	Orthosteric Ligand	alpha2a_off alpha2c_off
13.16	Consensus	alpha2a_off	Orthosteric Ligand	6KUX-α_2a-RS-79948
13.16	Consensus	gi_histamine	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/&β;1/&γ;2 8HOC-H₄-Imetit-Gi1/&β;1/&γ;2
13.16	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
13.16	Consensus	gs_5ht	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2 7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2 7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
13.16	Consensus	gs_histamine	Orthosteric Ligand	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
13.16	Consensus	h4_on	Orthosteric Ligand	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
13.16	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
13.04	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
13.04	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
13.04	Consensus	cx3cr_on	Orthosteric Ligand	cx3cr1_on
13.04	Consensus	vasopressin-ot_on	Orthosteric Ligand	ot_on v2_on
12.82	Single	3UZC	PubChem 135566609	3UZC-A_2A-PubChem 135566609
12.82	Single	4MQT	Iperoxo	4MQT-M₂-Iperoxo-LY2119620
12.82	Single	5TE3	Octyl Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl Beta-D-Glucopyranoside
12.82	Single	5UVI	ZM241385	5UVI-A_2A-ZM241385
12.82	Single	6A94	Zotepine	6A94-5-HT_2A-Zotepine
12.82	Single	6AQF	ZM241385	6AQF-A_2A-ZM241385
12.82	Single	6K41	Dexmedetomidine	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
12.82	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
12.82	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
12.82	Single	6TPG	EMPA	6TPG-OX₂-EMPA
12.82	Single	6WH4	Methiothepin	6WH4-5-HT_2A-Methiothepin
12.82	Single	6ZDV	PubChem 984073	6ZDV-A_2A-PubChem 984073-Na
12.82	Single	6ZFZ	77-LH-28-1	6ZFZ-M₁-77-LH-28-1
12.82	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
12.82	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2
12.82	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
12.82	Single	7CMU	Pramipexole	7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
12.82	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2
12.82	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/&β;1/&γ;2
12.82	Single	7RAN	PubChem 164575847	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
12.82	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
12.82	Single	7SR8	TAK-925	7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
12.82	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
12.82	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2
12.82	Single	7UM7	Methylergometrine	7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
12.82	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
12.82	Single	7XJJ	Galanin	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
12.82	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
12.82	Single	8GG3	Epinephrine	8GG3-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
12.82	Single	8GG5	Epinephrine	8GG5-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
12.82	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/&β;1/&γ;2
12.82	Single	8JSP	Ulotaront	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2
12.82	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
12.82	Single	8THK	A61603	8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
12.82	Single	8THL	Epinephrine	8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
12.82	Single	8UNR	Epinephrine	8UNR-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
12.82	Single	8UNS	Epinephrine	8UNS-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
12.82	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
12.82	Consensus	5ht5_on	Orthosteric Ligand	5ht5a_on
12.82	Consensus	5ht5a_on	Orthosteric Ligand	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
12.82	Consensus	alpha2b_on	Orthosteric Ligand	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
12.82	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
12.82	Consensus	d1_on_allo	Orthosteric Ligand	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2 7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
12.82	Consensus	d3_on	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
12.82	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
12.82	Consensus	go_galanin	Orthosteric Ligand	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
12.82	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-PubChem 25001412 5DHH-NOP-SB-612111
12.82	Consensus	ox2_off	Orthosteric Ligand	6TPN-OX₂-HTL6641 7XRR-OX₂-Lemborexant
12.82	Consensus	sensory_off	Orthosteric Ligand	opsin_off
12.77	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
12.77	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;2
12.50	Single	2VT4	Cyanopindolol	2VT4-β₁-Cyanopindolol
12.50	Single	2Y01	Dobutamine	2Y01-β₁-Dobutamine
12.50	Single	2Y02	Carmoterol	2Y02-β₁-Carmoterol
12.50	Single	2YCY	Cyanopindolol	2YCY-β₁-Cyanopindolol
12.50	Single	3ZPR	4-methyl-2-(piperazin-1-yl)	3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
12.50	Single	4QKX	PubChem 76210628	4QKX-β₂-PubChem 76210628
12.50	Single	4X1H	Nonyl Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl Beta-D-Glucopyranoside-Gt(CT)
12.50	Single	5DHG	PubChem 25001412	5DHG-NOP-PubChem 25001412
12.50	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
12.50	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
12.50	Single	5UIG	J3.651.884G	5UIG-A_2A-J3.651.884G
12.50	Single	6D27	CAY10471	6D27-DP₂-CAY10471
12.50	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
12.50	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
12.50	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
12.50	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
12.50	Single	6GPS	MK0812	6GPS-CCR2-MK0812
12.50	Single	6K42	Dexmedetomidine	6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
12.50	Single	6ORV	TT-OAD2	6ORV-GLP-1-TT-OAD2-Gs/&β;1/&γ;2
12.50	Single	6PRZ	(S)-Alprenolol	6PRZ-β₂-(S)-Alprenolol
12.50	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
12.50	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
12.50	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
12.50	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2
12.50	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
12.50	Single	7E32	Serotonin	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
12.50	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
12.50	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
12.50	Single	7UL4	Alvimopan	7UL4-μ-Alvimopan
12.50	Single	7VH0	Ramelteon	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
12.50	Single	7VIF	(S)-FTY720-P	7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2
12.50	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
12.50	Single	7XTC	5-CT	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
12.50	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/&β;1/&γ;2
12.50	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/&β;1/&γ;2
12.50	Single	8IRT	Rotigotine	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2
12.50	Single	8JLJ	T1AM	8JLJ-TA1-T1AM-chim(NtGi1-Gs)/&β;1/&γ;2
12.50	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/&β;1/&γ;2
12.50	Single	8WC7	ZH8667	8WC7-TA1-ZH8667-chim(NtGi1-Gs)/&β;1/&γ;2
12.50	Single	8X64	Desloratadine	8X64-H₁-Desloratadine
12.50	Consensus	5ht1a_on	Orthosteric Ligand	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2 7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
12.50	Consensus	5ht1d_on	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
12.50	Consensus	5ht7_on	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
12.50	Consensus	alpha2_on	Orthosteric Ligand	alpha2a_on alpha2b_on
12.50	Consensus	alpha_on	Orthosteric Ligand	alpha1_on alpha2_on
12.50	Consensus	cck_off	Orthosteric Ligand	ccka_off
12.50	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
12.50	Consensus	gi_5ht	Orthosteric Ligand	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2 8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2 7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2 7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2 7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2 7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
12.50	Consensus	gq_amine	Orthosteric Ligand	gq_muscarinic gq_histamine
12.50	Consensus	hca3_on	Orthosteric Ligand	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
12.50	Consensus	m2_on_allo	Orthosteric Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
12.50	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
12.50	Consensus	nmur_on	Orthosteric Ligand	nmur1_on nmur2_on
12.24	Consensus	gs_neuromedin	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
12.20	Single	2Y00	Dobutamine	2Y00-β₁-Dobutamine
12.20	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
12.20	Single	5CGC	HTL14242	5CGC-mGlu₅-HTL14242
12.20	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
12.20	Single	5WQC	EMPA	5WQC-OX₂-EMPA
12.20	Single	5XPR	Bosentan	5XPR-ET_B-Bosentan
12.20	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
12.20	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
12.20	Single	6GPX	MK0812	6GPX-CCR2-MK0812
12.20	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
12.20	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
12.20	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
12.20	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
12.20	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
12.20	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
12.20	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
12.20	Single	7WC6	LSD	7WC6-5-HT_2A-LSD
12.20	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/&β;1/&γ;2
12.20	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
12.20	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2
12.20	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
12.20	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
12.20	Consensus	5ht1_on	Orthosteric Ligand	5ht1a_on 5ht1d_on 5ht1e_on 5ht1f_on 5ht1b_on
12.20	Consensus	alpha2a_on	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
12.20	Consensus	ccr2_off_allo	Other Ligand	5T1A-CCR2-PubChem 68764898; PubChem 12093170 6GPX-CCR2-MK0812
12.20	Consensus	ep3_on	Orthosteric Ligand	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
12.20	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
12.20	Consensus	ep_off	Orthosteric Ligand	ep4_off
12.20	Consensus	go_amine	Orthosteric Ligand	go_adrenergic go_muscarinic go_5ht
12.20	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
11.90	Single	3PDS	Hydroxybenzylisoproterenol	3PDS-β₂-Hydroxybenzylisoproterenol
11.90	Single	4DJH	JDTic	4DJH-κ-JDTic
11.90	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
11.90	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
11.90	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
11.90	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2
11.90	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/&β;1/&γ;2
11.90	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
11.90	Single	7P2L	4YI	7P2L-mGlu₅-4YI
11.90	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
11.90	Single	7W41	PD176252	7W41-BB₂-PD176252
11.90	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
11.90	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
11.90	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2
11.90	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/&β;1/&γ;2
11.90	Single	8FMZ	Neurotensin/neuromedin N	8FMZ-NTS₁-Neurotensin/neuromedin N-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
11.90	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
11.90	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/&β;1/&γ;2
11.90	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
11.90	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
11.90	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
11.90	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
11.90	Consensus	go_adrenergic	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
11.90	Consensus	gs_ffa	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2 8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
11.90	Consensus	kop_off	Orthosteric Ligand	4DJH-κ-JDTic
11.90	Consensus	nk1_off	Orthosteric Ligand	6J20-NK₁-Aprepitant 6HLL-NK₁-CP99994 6E59-NK₁-L-760735
11.90	Consensus	nts1_on_allo	Orthosteric Ligand	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
11.90	Consensus	sst4_on	Orthosteric Ligand	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
11.63	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
11.63	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
11.63	Single	6ZG4	HTL0009936	6ZG4-M₁-HTL0009936
11.63	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1
11.63	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
11.63	Single	7L1V	PubChem 155491009	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
11.63	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
11.63	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
11.63	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
11.63	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/&β;1/&γ;2
11.63	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
11.63	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
11.63	Consensus	gi_class-f	Other Ligand	gi_frizzled
11.63	Consensus	gi_frizzled	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
11.63	Consensus	gs_trh	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
11.63	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
11.43	Single	7XKE	Betahydroxyandrosterone	7XKE-ADGRG2-Betahydroxyandrosterone-chim(NtGi1-Gs)/&β;1/&γ;2
11.43	Single	8HSC	Fab046	8HSC-GPR20-Fab046-Gi1/&β;1/&γ;2
11.36	Single	6K1Q	IRL2500	6K1Q-ET_B-IRL2500
11.36	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/&β;1/&γ;2
11.36	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2
11.36	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/&β;1/&γ;2
11.36	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
11.36	Consensus	ep2_on	Orthosteric Ligand	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
11.36	Consensus	ffa4_on_allo	Orthosteric Ligand	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
11.36	Consensus	ot_on	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
11.11	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
11.11	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
11.11	Single	8DPH	Lorcaserin	8DPH-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
11.11	Single	8INR	Alpha-MSH	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
11.11	Single	8IWM	2-Phenylethylamine	8IWM-TAAR9-2-Phenylethylamine
11.11	Consensus	go_vasopressin	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
10.87	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
10.87	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
10.87	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
10.81	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
10.81	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
10.81	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
10.81	Single	8GGZ	Epinephrine	8GGZ-β₂-Epinephrine
10.81	Single	8JXT	Histamine	8JXT-H₄-Histamine-PO4-Gi1/&β;1/&γ;2
10.81	Single	8POK	Histamine	8POK-H₂-Histamine-Gs/&β;1/&γ;2
10.81	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
10.81	Consensus	smo_off_allo	Orthosteric Ligand	6D32-SMO-Cyclopamine-Cyclopamine
10.64	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/&β;1/&γ;2
10.64	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2
10.64	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
10.53	Single	1U19	11-cis-Retinal	1U19-Rhodopsin-11-cis-Retinal
10.53	Single	2G87	All-trans-retinal	2G87-Rhodopsin-All-trans-retinal
10.53	Single	2I35	11-cis-Retinal	2I35-Rhodopsin-11-cis-Retinal
10.53	Single	3PBL	Eticlopride	3PBL-D₃-Eticlopride
10.53	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
10.53	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
10.53	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
10.53	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
10.53	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
10.53	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
10.53	Single	7DFL	Histamine	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
10.53	Single	7SRQ	LSD	7SRQ-5-HT_2B-LSD
10.53	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
10.53	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
10.53	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/&β;1/&γ;2
10.53	Single	7XP6	Strychnine	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
10.53	Single	7XTB	Serotonin	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2
10.53	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2
10.53	Single	8ITF	DMCHA	8ITF-TAAR9-DMCHA-chim(NtGi1-Gs)/&β;1/&γ;2
10.53	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/&β;1/&γ;2
10.53	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab-Cholesterol
10.53	Single	8W8B	SEP-363856	8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
10.53	Consensus	class-t_on	Orthosteric Ligand	taste2_on
10.53	Consensus	d3_off	Orthosteric Ligand	3PBL-D₃-Eticlopride
10.53	Consensus	go_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
10.53	Consensus	go_protein	Orthosteric Ligand	go_chemokine
10.53	Consensus	gq_histamine	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
10.53	Consensus	gs_class-t	Orthosteric Ligand	gs_taste
10.53	Consensus	gs_taste	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
10.53	Consensus	h1_on	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
10.53	Consensus	m4_on_allo	Other Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
10.53	Consensus	smo_on_allo	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
10.53	Consensus	taste2_on	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
10.42	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
10.42	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
10.26	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
10.26	Single	2PED	9-cis-Retinal	2PED-Rhodopsin-9-cis-Retinal
10.26	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
10.26	Single	3PWH	ZM241385	3PWH-A_2A-ZM241385
10.26	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
10.26	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
10.26	Single	6B73	PubChem 131955138	6B73-κ-PubChem 131955138
10.26	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
10.26	Single	6NWE	Octyl Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
10.26	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
10.26	Single	6OYA	All-trans-retinal	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
10.26	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
10.26	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
10.26	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
10.26	Single	7F24	Dopamine	7F24-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
10.26	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
10.26	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
10.26	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
10.26	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
10.26	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
10.26	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
10.26	Single	7SRR	LSD	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
10.26	Single	7SRS	LSD	7SRS-5-HT_2B-LSD-Arrestin2
10.26	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2
10.26	Single	7T94	PubChem 57664406	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
10.26	Single	7TUZ	7alpha,25-dihydroxycholesterol	7TUZ-GPR183-7alpha,25-dihydroxycholesterol-Gi1/&β;1/&γ;2
10.26	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
10.26	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/&β;1/&γ;2
10.26	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
10.26	Single	7X2F	Dopamine	7X2F-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
10.26	Single	8FN0	Neurotensin/neuromedin N	8FN0-NTS₁-Neurotensin/neuromedin N-PubChem 118610427-chim(NtGi1-Go)/&β;1/&γ;2
10.26	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
10.26	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
10.26	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
10.26	Consensus	class-f_off	Orthosteric Ligand	smo_off
10.26	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
10.26	Consensus	gt_class-a	Orthosteric Ligand	gt_opsin
10.26	Consensus	gt_opsin	Orthosteric Ligand	gt_sensory
10.26	Consensus	gt_sensory	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
10.26	Consensus	m2_on_allo	Other Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
10.26	Consensus	melatonin_on	Orthosteric Ligand	mt1_on mt2_on
10.26	Consensus	opsin_off	Orthosteric Ligand	1U19-Rhodopsin-11-cis-Retinal 2PED-Rhodopsin-9-cis-Retinal 5TE5-Rhodopsin-20-Methanoretinal
10.26	Consensus	orexin_off	Orthosteric Ligand	ox2_off ox1_off
10.26	Consensus	p2y_off	Orthosteric Ligand	p2y1_off p2y12_off
10.20	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
10.00	Single	3REY	PubChem 5697	3REY-A_2A-PubChem 5697
10.00	Single	3RZE	Cidoxepin	3RZE-H₁-Cidoxepin
10.00	Single	4DKL	Beta-funaltrexamine	4DKL-μ-Beta-funaltrexamine
10.00	Single	4ZJC	SB-674042	4ZJC-OX₁-SB-674042
10.00	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
10.00	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
10.00	Single	6IQL	L745870	6IQL-D₄-L745870
10.00	Single	6MH8	ZM241385	6MH8-A_2A-ZM241385
10.00	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
10.00	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
10.00	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
10.00	Single	6TPN	HTL6641	6TPN-OX₂-HTL6641
10.00	Single	6V9S	GTPL11403	6V9S-OX₁-GTPL11403
10.00	Single	6VI4	JDTic	6VI4-κ-JDTic
10.00	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
10.00	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
10.00	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
10.00	Single	6ZG9	GSK1034702	6ZG9-M₁-GSK1034702
10.00	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/&β;1/&γ;2
10.00	Single	7E33	BRL-54443	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
10.00	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
10.00	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
10.00	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
10.00	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/&β;1/&γ;2
10.00	Single	7ZBE	11-cis-Retinal	7ZBE-Rhodopsin-11-cis-Retinal
10.00	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
10.00	Single	8DPG	Psilocin	8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
10.00	Single	8FCZ	11-cis-Retinal	8FCZ-Rhodopsin-11-cis-Retinal
10.00	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
10.00	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
10.00	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
10.00	Single	8JD6	N-(3-chlorophenyl)pyridine-2-carboxamide	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
10.00	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/&β;1/&γ;2
10.00	Consensus	5ht1e_on	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
10.00	Consensus	cxcr_on	Orthosteric Ligand	cxcr1_on cxcr2_on
10.00	Consensus	gi_class-f	Orthosteric Ligand	gi_frizzled
10.00	Consensus	gi_frizzled	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
10.00	Consensus	gi_melatonin	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2 7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
10.00	Consensus	m1_off_allo	Other Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
10.00	Consensus	ox1_off	Orthosteric Ligand	6TOT-OX₁-Lemborexant 6TP4-OX₁-ACT-462206 6TP6-OX₁-Filorexant 6V9S-OX₁-GTPL11403 6TP3-OX₁-Nemorexant 6TQ6-OX₁-PubChem 145714283 6TQ7-OX₁-SB-334867 6TQ9-OX₁-SB-408124 4ZJC-OX₁-SB-674042 4ZJ8-OX₁-Suvorexant
9.76	Single	1HZX	11-cis-Retinal	1HZX-Rhodopsin-11-cis-Retinal
9.76	Single	4EJ4	Naltrindole	4EJ4-δ-Naltrindole
9.76	Single	4QIM	PubChem 24905375	4QIM-SMO-PubChem 24905375
9.76	Single	6IIV	Daltroban	6IIV-TP-Daltroban
9.76	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
9.76	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
9.76	Single	7BU7	BI167107	7BU7-β₁-BI167107
9.76	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
9.76	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
9.76	Single	7SCG	FH210	7SCG-μ-FH210-Gi1/&β;1/&γ;2
9.76	Single	7SQO	TAK-925	7SQO-OX₂-TAK-925-Gi1/&β;1/&γ;2
9.76	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
9.76	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
9.76	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
9.76	Single	8ID4	Linoleic acid	8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2
9.76	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
9.76	Consensus	blt_on	Orthosteric Ligand	blt1_on
9.76	Consensus	dop_off	Orthosteric Ligand	4EJ4-δ-Naltrindole
9.76	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
9.76	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
9.76	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
9.76	Consensus	hcar_off	Orthosteric Ligand	succinate_off
9.76	Consensus	leuko_on	Orthosteric Ligand	blt_on
9.76	Consensus	prostanoid_off	Orthosteric Ligand	ep_off tp_off dp_off
9.76	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
9.76	Consensus	tachykinin_off	Orthosteric Ligand	nk1_off
9.76	Consensus	tp_off	Orthosteric Ligand	6IIV-TP-Daltroban 6IIU-TP-Ramatroban
9.52	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
9.52	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/&β;1/&γ;2
9.52	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
9.52	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
9.52	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
9.52	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
9.52	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
9.52	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
9.52	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
9.52	Single	7Y27	Somatostatin-14	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
9.52	Consensus	gs_sst	Orthosteric Ligand	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
9.30	Single	6E59	L-760735	6E59-NK₁-L-760735
9.30	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/&β;1/&γ;2
9.30	Single	7R0C	Acyclovir triphosphate	7R0C-V₂-Acyclovir triphosphate-Arrestin2
9.30	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
9.30	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
9.30	Consensus	cyslt1_off_ortoallo	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
9.30	Consensus	gi_ffa	Orthosteric Ligand	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2 8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
9.09	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
9.09	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2
9.09	Single	8DWC	Proenkephalin-A	8DWC-MRGPRX1-Proenkephalin-A-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
9.09	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
9.09	Consensus	chemokine_off	Orthosteric Ligand	cxcr_off
9.09	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II
9.09	Consensus	cxcr_off	Orthosteric Ligand	cxcr4_off
8.89	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
8.89	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
8.82	Single	8HS2	Fab046	8HS2-GPR20-Fab046
8.70	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
8.70	Single	8SAI	1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine	8SAI-GPR34-1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-Gi1/&β;1/&γ;2
8.57	Single	8WCB	Cyclohexylammonium ion	8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8.57	Single	8WCC	Cyclohexylammonium ion	8WCC-TA1-Cyclohexylammonium ion
8.51	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/&β;1/&γ;2
8.51	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/&β;1/&γ;2
8.51	Consensus	nmur1_on	Orthosteric Ligand	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8.33	Single	5MZJ	Theophylline	5MZJ-A_2A-Theophylline-Na
8.33	Single	6VCB	LSN3160440	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
8.33	Single	7V68	PubChem 57664406	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
8.33	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8.33	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/&β;1/&γ;2
8.33	Single	8IOC	Gamma-MSH	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
8.33	Single	8PWN	Theophylline	8PWN-A_2A-Theophylline
8.33	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
8.33	Consensus	class-c_on	Other Ligand	gabab_on mglu_on
8.11	Single	2HPY	All-trans-retinal	2HPY-Rhodopsin-All-trans-retinal
8.11	Single	3RFM	Caffeine	3RFM-A_2A-Caffeine
8.11	Single	6TQ9	SB-408124	6TQ9-OX₁-SB-408124
8.11	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
8.11	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
8.11	Single	7MTB	All-trans-retinal	7MTB-Rhodopsin-All-trans-retinal-GRK1
8.11	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/&β;1/&γ;2
8.11	Single	8WC5	Tetramethylammonium ion	8WC5-TA1-Tetramethylammonium ion-chim(NtGi1-Gs)/&β;1/&γ;2
7.89	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
7.89	Single	3C9M	11-cis-Retinal	3C9M-Rhodopsin-11-cis-Retinal
7.89	Single	3OE8	IT1t	3OE8-CXCR4-IT1t
7.89	Single	3UZA	GTPL9236	3UZA-A_2A-GTPL9236
7.89	Single	5WKT	Octyl Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
7.89	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
7.89	Single	6FUF	All-trans-retinal	6FUF-Rhodopsin-All-trans-retinal-Go/&β;1/&γ;2
7.89	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
7.89	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
7.89	Single	6OIK	LY2119620	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
7.89	Single	7MT8	All-trans-retinal	7MT8-Rhodopsin-All-trans-retinal-GRK1
7.89	Single	7MT9	All-trans-retinal	7MT9-Rhodopsin-All-trans-retinal-GRK1
7.89	Single	7MTA	All-trans-retinal	7MTA-Rhodopsin-All-trans-retinal-GRK1
7.89	Single	8F76	-	8F76-OR51E2-Gs/&β;1/&γ;2
7.89	Single	8IU2	Retinal	8IU2-Opsin1LW-Retinal-Gi1/&β;1/&γ;2
7.89	Consensus	adgrg3_on	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
7.69	Single	1L9H	11-cis-Retinal	1L9H-Rhodopsin-11-cis-Retinal
7.69	Single	5TE5	20-Methanoretinal	5TE5-Rhodopsin-20-Methanoretinal
7.69	Single	6HLL	CP99994	6HLL-NK₁-CP99994
7.69	Single	6QNO	All-trans-retinal	6QNO-Rhodopsin-All-trans-retinal-Gi1/&β;1/&γ;1
7.69	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
7.69	Single	7E2Y	Serotonin	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
7.69	Single	7UL2	SR48692	7UL2-NTS₁-SR48692-Na
7.69	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
7.69	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/&β;1/&γ;2
7.69	Consensus	mt1_on	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
7.69	Consensus	mt2_on	Orthosteric Ligand	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
7.69	Consensus	nts1_off_allo	Orthosteric Ligand	7UL2-NTS₁-SR48692-Na
7.50	Single	1GZM	11-cis-Retinal	1GZM-Rhodopsin-11-cis-Retinal
7.50	Single	3C9L	11-cis-Retinal	3C9L-Rhodopsin-11-cis-Retinal
7.50	Single	5WS3	EMPA	5WS3-OX₂-EMPA
7.50	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
7.50	Single	6TOD	EMPA	6TOD-OX₁-EMPA-Na
7.50	Single	7LJD	Dopamine	7LJD-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;1
7.50	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
7.50	Single	7XRR	Lemborexant	7XRR-OX₂-Lemborexant
7.50	Single	8A6C	All-trans-retinal	8A6C-Rhodopsin-All-trans-retinal
7.50	Single	8A6D	All-trans-retinal	8A6D-Rhodopsin-All-trans-retinal
7.50	Single	8A6E	All-trans-retinal	8A6E-Rhodopsin-All-trans-retinal
7.50	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7.50	Single	8U8F	PML	8U8F-GPR3-PML-Gs/&β;1/&γ;2
7.50	Consensus	smo_on_allo	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
7.32	Single	3OAX	11-cis-Retinal	3OAX-Rhodopsin-11-cis-Retinal
7.32	Single	4N6H	Naltrindole	4N6H-δ-Naltrindole-Na
7.32	Single	6DS0	Ly266097	6DS0-5-HT_2B-Ly266097
7.32	Single	6FFI	MMPEP	6FFI-mGlu₅-MMPEP
7.32	Single	7EJ8	Brimonidine	7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2
7.32	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
7.32	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
7.32	Single	7ZBC	11-cis-Retinal	7ZBC-Rhodopsin-11-cis-Retinal
7.32	Single	8HQN	9(S)-HODE	8HQN-GPR132-9(S)-HODE-Gi1/&β;1/&γ;2
7.32	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
7.32	Consensus	dop_off_allo	Orthosteric Ligand	4N6H-δ-Naltrindole-Na
7.32	Consensus	ffa2_on	Orthosteric Ligand	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
7.14	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
7.14	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
7.14	Consensus	ffa_on	Orthosteric Ligand	ffa4_on ffa1_on ffa2_on ffa3_on
6.98	Single	4PHU	Fasiglifam	4PHU-FFA1 (GPR40)-Fasiglifam
6.98	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
6.98	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
6.82	Single	5TZR	-	5TZR-FFA1 (GPR40)-MK8666
6.82	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
6.82	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
6.67	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
6.67	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
6.67	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.67	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
6.67	Consensus	nts1_off	Orthosteric Ligand	6Z4Q-NTS₁-SR142948A 6Z4S-NTS₁-SR48692
6.67	Consensus	nts_off	Orthosteric Ligand	nts1_off
6.52	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
6.52	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1 (GPR40)-MK8666; PubChem 127053597
6.38	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
6.12	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
5.56	Single	5MZP	Caffeine	5MZP-A_2A-Caffeine-Na
5.41	Single	7WC4	Serotonin	7WC4-5-HT_2A-Serotonin
5.41	Consensus	gabab_off	Other Ligand	7C7S-GABA_B1, GABA_B2-CGP54626 7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid 6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
5.26	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
5.26	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Cholesterol-Gi1/&β;1/&γ;2
5.26	Consensus	sensory_on	Orthosteric Ligand	opsin_on
5.13	Single	2ZIY	11-cis-Retinal	2ZIY-Rhodopsin-11-cis-Retinal
5.13	Single	3PQR	All-trans-retinal	3PQR-Rhodopsin-All-trans-retinal-Gt(CT)
5.13	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
5.13	Single	7V6A	PubChem 9864275	7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
5.13	Single	7WC5	Psilocin	7WC5-5-HT_2A-Psilocin
5.13	Single	8EIT	Doconexent	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
5.13	Single	8J21	Butyric acid	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
5.13	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2
5.13	Consensus	ffa3_on	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
5.13	Consensus	opsin_on	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
5.00	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
5.00	Single	6TP4	ACT-462206	6TP4-OX₁-ACT-462206
5.00	Single	6TQ4	PubChem 16046844	6TQ4-OX₁-PubChem 16046844-Na
5.00	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
5.00	Single	8JII	Compound 9n	8JII-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
5.00	Single	8X2K	5YM	8X2K-GPR3-5YM-chim(NtGi1-Gs)/&β;1/&γ;2
5.00	Consensus	ox1_off_allo	Orthosteric Ligand	6TOD-OX₁-EMPA-Na 6TOS-OX₁-GSK1059865-Na 6TQ4-OX₁-PubChem 16046844-Na 6TO7-OX₁-Suvorexant-Na
4.88	Single	8DWH	Compound-16	8DWH-MRGPRX1-Compound-16-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.88	Single	8J20	Valeric acid	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
4.88	Single	8J6P	Compound 9n	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
4.88	Single	8JHY	Compound 9n	8JHY-HCA₂-Compound 9n-Gi1/&β;1/&γ;2
4.88	Consensus	ffa3_on_allo	Orthosteric Ligand	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
4.76	Single	6TPK	Retosiban	6TPK-OT-Retosiban
4.76	Single	7EJA	Dexmedetomidine	7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
4.76	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/&β;1/&γ;2
4.76	Single	8T3V	DHA	8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.76	Consensus	ot_off	Orthosteric Ligand	6TPK-OT-Retosiban
4.76	Consensus	vasopressin-ot_off	Orthosteric Ligand	ot_off
4.65	Single	8EJC	TAK-875	8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
4.65	Single	8EJK	TAK-875	8EJK-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
4.65	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/&β;1/&γ;2
4.65	Consensus	ffa1_on	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.65	Consensus	p2y12_off	Orthosteric Ligand	4NTJ-P2Y₁₂-AZD1283 7PP1-P2Y₁₂-Selatogrel
4.55	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
4.55	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
4.55	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
4.35	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
4.35	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/&β;1/&γ;2
4.26	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
4.26	Consensus	cyslt2_off	Orthosteric Ligand	6RZ6-CysLT₂-ONO-2570366 6RZ9-CysLT₂-ONO-2770372 6RZ8-CysLT₂-ONO-2080365
4.26	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off
4.08	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
4.00	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
2.94	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
2.94	Single	6D35	Cholesterol	6D35-SMO-Cholesterol
2.94	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
2.94	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
2.94	Single	6UO8	SKF97541	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
2.94	Single	6UO9	SKF97541	6UO9-GABA_B1, GABA_B2-SKF97541
2.94	Single	6W2X	PubChem 5311042	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
2.94	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
2.94	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
2.94	Single	7C7Q	Baclofen	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
2.94	Single	7C7S	CGP54626	7C7S-GABA_B1, GABA_B2-CGP54626
2.94	Single	7CUM	CGP54626	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
2.94	Single	7DD5	Ca3	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
2.94	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
2.94	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
2.94	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
2.94	Single	7DGE	Quisqualate	7DGE-mGlu1; mGlu1-Quisqualate
2.94	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
2.94	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
2.94	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
2.94	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
2.94	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
2.94	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
2.94	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
2.94	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
2.94	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
2.94	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
2.94	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
2.94	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
2.94	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
2.94	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
2.94	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
2.94	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
2.94	Single	7EB2	Baclofen	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
2.94	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
2.94	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
2.94	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
2.94	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
2.94	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
2.94	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
2.94	Single	7FIH	hCG	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
2.94	Single	7FII	hCG	7FII-LH-hCG-6fuf
2.94	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
2.94	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
2.94	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
2.94	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
2.94	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
2.94	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
2.94	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
2.94	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
2.94	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
2.94	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
2.94	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
2.94	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
2.94	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
2.94	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
2.94	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
2.94	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
2.94	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
2.94	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
2.94	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
2.94	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
2.94	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
2.94	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
2.94	Single	7T9N	M22 Fab	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
2.94	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
2.94	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
2.94	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
2.94	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
2.94	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
2.94	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
2.94	Single	7XW6	M22 Fab	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
2.94	Single	7XW7	K1-70	7XW7-TSH-K1-70
2.94	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
2.94	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
2.94	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
2.94	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
2.94	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
2.94	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
2.94	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
2.94	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
2.94	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
2.94	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
2.94	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
2.94	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
2.94	Single	8JD0	Glutamate	8JD0-mGlu2; mGlu3-Glutamate-J9R
2.94	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
2.94	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
2.94	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
2.94	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
2.94	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
2.94	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
2.94	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
2.94	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
2.94	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
2.94	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
2.94	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
2.94	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
2.94	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
2.94	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
2.94	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
2.94	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
2.94	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
2.94	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
2.94	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
2.94	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
2.94	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
2.94	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
2.94	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
2.94	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
2.94	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
2.94	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
2.94	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
2.94	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
2.94	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
2.94	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
2.94	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
2.94	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
2.94	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
2.94	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
2.94	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
2.94	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
2.94	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
2.94	Consensus	class-c_off	Orthosteric Ligand	gabab_off mglu_off
2.94	Consensus	class-c_off	Orthosteric Ligand	gabab_off mglu_off
2.94	Consensus	class-c_off	Other Ligand	gabab_off mglu_off
2.94	Consensus	class-c_on	Orthosteric Ligand	gabab_on mglu_on
2.94	Consensus	class-c_on	Orthosteric Ligand	gabab_on mglu_on
2.94	Consensus	fsh_on_allo	Orthosteric Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
2.94	Consensus	gabab_off	Orthosteric Ligand	7C7S-GABA_B1, GABA_B2-CGP54626 7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid 6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
2.94	Consensus	gabab_on	Orthosteric Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
2.94	Consensus	gi_class-c	Orthosteric Ligand	gi_mglu gi_gaba
2.94	Consensus	gi_class-c	Orthosteric Ligand	gi_mglu gi_gaba
2.94	Consensus	gi_gaba	Orthosteric Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
2.94	Consensus	gi_mglu	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
2.94	Consensus	gi_mglu	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
2.94	Consensus	gphr_on	Orthosteric Ligand	lh_on tsh_on
2.94	Consensus	gs_gphr	Orthosteric Ligand	7T9I-TSH-TSH-Gs/&β;1/&γ;2 7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
2.94	Consensus	gs_protein	Orthosteric Ligand	gs_gphr
2.94	Consensus	lh_on	Orthosteric Ligand	7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
2.94	Consensus	lh_on_allo	Orthosteric Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
2.94	Consensus	mglu2_off	Orthosteric Ligand	7MTQ-mGlu2; mGlu2-LY341495
2.94	Consensus	mglu2_off	Orthosteric Ligand	7MTQ-mGlu2; mGlu2-LY341495
2.94	Consensus	mglu2_on	Orthosteric Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
2.94	Consensus	mglu2_on	Orthosteric Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
2.94	Consensus	mglu3_off	Orthosteric Ligand	7WI8-mGlu3; mGlu3-LY341495 7WIH-mGlu3; mGlu3-LY2794193
2.94	Consensus	mglu3_off	Orthosteric Ligand	7WI8-mGlu3; mGlu3-LY341495 7WIH-mGlu3; mGlu3-LY2794193
2.94	Consensus	mglu4_on	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
2.94	Consensus	mglu4_on	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
2.94	Consensus	mglu5_off	Orthosteric Ligand	7FD9-mGlu5; mGlu5-LY341495
2.94	Consensus	mglu5_off	Orthosteric Ligand	7FD9-mGlu5; mGlu5-LY341495
2.94	Consensus	mglu_off	Orthosteric Ligand	mglu2_off mglu3_off mglu5_off
2.94	Consensus	mglu_off	Orthosteric Ligand	mglu2_off mglu3_off mglu5_off
2.94	Consensus	mglu_on	Orthosteric Ligand	mglu2_on mglu4_on
2.94	Consensus	mglu_on	Orthosteric Ligand	mglu2_on mglu4_on
2.94	Consensus	smo_off_allo	Other Ligand	6D32-SMO-Cyclopamine-Cyclopamine
2.94	Consensus	tsh_on	Orthosteric Ligand	7T9I-TSH-TSH-Gs/&β;1/&γ;2
2.94	Consensus	tsh_on_allo	Orthosteric Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
2.86	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
2.86	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
2.86	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
2.86	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
2.86	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
2.86	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
2.86	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
2.86	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
2.86	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
2.86	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
2.78	Single	7KNU	Calcitonin gene-related peptide-1	7KNU-CT Like-Calcitonin gene-related peptide-1-RAMP1
2.78	Single	7T9M	CS-17 Antibody	7T9M-TSH-CS-17 Antibody
2.70	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
2.70	Single	6W25	Ca	6W25-MC₄-SHU9119-Ca
2.70	Single	7FIG	hCG	7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
2.70	Single	7UTZ	TR1402	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
2.70	Single	7XW5	TSH	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
2.70	Single	7ZI0	Cholesterol	7ZI0-SMO-SAG-Cholesterol
2.70	Single	8TLM	Anti-murine CCR8 antibody	8TLM-CCR8-Anti-murine CCR8 antibody
2.70	Consensus	ccr8_off	Orthosteric Ligand	8TLM-CCR8-Anti-murine CCR8 antibody
2.63	Single	3PXO	All-trans-retinal	3PXO-Rhodopsin-All-trans-retinal
2.63	Single	5DYS	All-trans-retinal	5DYS-Rhodopsin-All-trans-retinal
2.63	Single	5L7D	Cholesterol	5L7D-SMO-Cholesterol
2.63	Single	7T9I	TSH	7T9I-TSH-TSH-Gs/&β;1/&γ;2
2.63	Single	8I2G	Glycoprotein hormones alpha chain	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
2.56	Single	6OY9	All-trans-retinal	6OY9-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
2.56	Single	7VDM	Substance P	7VDM-MRGPRX2-Substance P-Gi1/&β;1/&γ;2
2.50	Single	7F61	Cholesterol	7F61-H₃-PF-03654746-Cholesterol
2.50	Single	7S8O	(R)-Zinc-3573	7S8O-MRGPRX2-(R)-Zinc-3573-Gi1/&β;1/&γ;2
2.50	Consensus	gip_on_allo	Other Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
2.50	Consensus	h3_on_allo	Other Ligand	7F61-H₃-PF-03654746-Cholesterol
2.44	Single	6I9K	9-cis-Retinal	6I9K-Rhodopsin-9-cis-Retinal
2.44	Single	7S8N	(R)-Zinc-3573	7S8N-MRGPRX2-(R)-Zinc-3573-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
2.44	Single	8J6Q	Compound 9n	8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
2.44	Consensus	hca2_on_allo	Other Ligand	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2 8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
2.38	Single	4K5Y	CP-376395	4K5Y-CRF₁-CP-376395
2.38	Single	4XNV	BPTU	4XNV-P2Y₁-BPTU
2.38	Single	6C1Q	NDT9513727	6C1Q-C5a₁-PMX53-NDT9513727
2.38	Single	6TQ6	PubChem 145714283	6TQ6-OX₁-PubChem 145714283
2.38	Single	8HNN	SCH546738	8HNN-CXCR3-SCH546738
2.33	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
2.33	Single	8IYX	YL-365	8IYX-GPR34-YL-365
2.27	Single	4Z9G	CP-376395	4Z9G-CRF₁-CP-376395
2.27	Single	8GTI	BMK-C205	8GTI-CRF₁-BMK-C205
2.22	Single	8GTG	BMK-I152	8GTG-CRF₁-BMK-I152
2.13	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
2.13	Single	8GTM	BMK-C203	8GTM-CRF₁-BMK-C203
2.08	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7

Consensus Members
	Id	Members
	gs_glucagon	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 6WZG-Secretin-Secretin-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2 7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2 7DTY-GIP-GIP-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
	gs_vip-pacap	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
	gs_pth	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7F16-PTH2-TIP39-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
	gs_calcitonin	gs_ct gs_cgrp
	gs_crf	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2

Net Summary
I_min	3.07772
Number of Linked Nodes	1069
Number of Links	1261
Number of Hubs	191
Number of Links mediated by Hubs	778
Number of Communities	21
Number of Nodes involved in Communities	228
Number of Links involved in Communities	351

Path Summary
Number Of Nodes in MetaPath	119
Number Of Links MetaPath	118
Number of Shortest Paths	2882427
Length Of Smallest Path	3
Average Path Length	36.4852
Length of Longest Path	86
Minimum Path Strength	0.23405
Average Path Strength	6.336
Maximum Path Strength	34.4307
Minimum Path Correlation	0.700405
Average Path Correlation	0.975704
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.49254
Average % Of Corr. Nodes	33.0239
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	42.7407
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

This network is also present in following consensuses:
	Id	Components
	gs_class-b	gs_class-b1 gs_class-b2

You can download a compressed (zip) file with structure(s), 3D outputs (as PyMol and VMD scripts) and numerical data files (as csv and plain text files).

Download gs_class-b1.zip

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