psnGPCR

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Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	G.HN.30	G.HN.33	6.09702	Yes	No	0	8	4
2	G.HN.37	G.HN.41	3.7346	No	No	0	2	4
3	G.HN.39	b.b5x5	3.65147	No	Yes	0	4	5
4	G.HN.40	b.b5x2	6.02977	No	Yes	0	7	7
5	G.HN.43	b.b5x3	4.89953	No	Yes	0	8	9
6	G.HN.44	b.b5x3	7.84821	No	Yes	0	6	9
7	G.HN.47	b.b4x2	2.65438	No	No	0	6	8
8	G.HN.50	b.b4x2	5.0055	Yes	No	0	5	8
9	G.S1.01	G.S3.02	9.34993	No	No	0	6	3
10	G.S1.02	G.S3.03	7.03954	Yes	Yes	3	4	7
11	G.S1.02	G.h2s4.05	5.016	Yes	No	0	4	7
12	G.S1.03	G.S3.06	6.60712	No	Yes	0	9	6
13	G.S1.04	G.S3.03	2.56692	Yes	Yes	3	7	7
14	G.S1.04	G.S4.03	3.25329	Yes	Yes	3	7	7
15	G.S1.05	G.S1.07	6.44331	Yes	No	0	9	9
16	G.S1.05	G.h2s4.01	8.43499	Yes	Yes	0	9	9
17	G.S1.05	G.S4.02	2.76334	Yes	Yes	0	9	7
18	G.H1.01	G.S1.06	5.2696	No	Yes	3	9	8
19	G.S1.06	G.S3.05	3.64821	Yes	Yes	0	8	6
20	G.S1.06	G.S3.07	3.14398	Yes	Yes	3	8	9
21	G.S1.06	G.S4.03	3.09738	Yes	Yes	3	8	7
22	G.H3.12	G.S1.07	3.67865	No	No	0	8	9
23	G.H1.04	G.S4.05	3.19634	No	No	3	7	7
24	G.H1.04	G.S5.05	3.30045	No	Yes	3	7	9
25	G.hfs2.07	b.l7x4	4.16448	No	Yes	0	8	9
26	G.S2.01	G.S3.08	2.69532	No	No	0	9	9
27	G.S2.01	b.l5x5	6.44241	No	Yes	0	9	9
28	G.S2.03	G.S3.04	9.97418	No	No	2	8	6
29	G.S2.03	G.S3.06	9.29098	No	Yes	2	8	6
30	G.S2.05	G.S3.02	5.84413	No	No	0	3	3
31	G.S2.06	G.S3.03	12.0485	Yes	Yes	0	8	7
32	G.S2.08	G.s2s3.01	9.69069	Yes	No	3	5	4
33	G.H5.04	G.S2.08	5.60318	No	Yes	0	7	5
34	G.H5.05	G.S2.08	3.83225	Yes	Yes	3	5	5
35	G.H5.08	G.S2.08	6.19956	Yes	Yes	3	8	5
36	G.H5.08	G.s2s3.01	7.34736	Yes	No	3	8	4
37	G.S3.01	G.S3.03	5.92371	Yes	Yes	3	4	7
38	G.H5.08	G.S3.01	2.79232	Yes	Yes	3	8	4
39	G.H5.11	G.S3.03	3.67086	No	Yes	3	8	7
40	G.S3.04	G.S3.06	7.8114	No	Yes	2	6	6
41	G.S3.06	G.h2s4.01	4.59529	Yes	Yes	2	6	9
42	G.S3.06	b.l5x5	11.116	Yes	Yes	2	6	9
43	G.H2.07	G.S3.08	8.1859	Yes	No	0	9	9
44	G.S3.08	G.h2s4.01	2.41431	No	Yes	0	9	9
45	G.H2.07	G.s3h2.03	7.89827	Yes	No	2	9	9
46	G.s3h2.03	b.l7x4	3.74733	No	Yes	0	9	9
47	G.s3h2.03	b.l9x6	5.34406	No	Yes	2	9	8
48	G.H2.02	b.l9x6	4.90606	No	Yes	2	8	8
49	G.H2.02	b.l13x6	5.85833	No	Yes	2	8	9
50	G.H2.03	G.H2.05	7.07036	No	No	2	9	7
51	G.H2.04	G.H2.07	5.06413	No	Yes	0	9	9
52	G.H2.04	G.H3.08	4.08028	No	No	0	9	9
53	G.H2.05	G.H2.06	2.91273	No	Yes	2	7	9
54	G.H2.06	b.l9x6	3.12706	Yes	Yes	2	9	8
55	G.H2.06	b.b14x1	6.43543	Yes	No	2	9	8
56	G.H2.06	b.l17x6	7.7046	Yes	No	2	9	9
57	G.H2.07	b.l9x6	3.5906	Yes	Yes	2	9	8
58	G.H2.09	G.H2.10	4.01434	Yes	No	12	8	6
59	G.H2.09	G.H3.17	4.59794	Yes	Yes	0	8	4
60	G.H2.09	b.b2x1	8.56574	Yes	Yes	12	8	8
61	G.H2.09	b.l28x1	3.95789	Yes	Yes	12	8	9
62	G.H2.10	b.b2x1	3.55462	No	Yes	12	6	8
63	G.h2s4.01	b.l5x5	7.10375	Yes	Yes	2	9	9
64	G.h2s4.02	G.h2s4.03	2.53071	No	No	0	7	5
65	G.h2s4.02	b.l1x6	4.30929	No	No	0	7	9
66	G.H3.18	G.S4.02	5.28161	Yes	Yes	19	9	7
67	G.S4.02	G.S5.02	2.66886	Yes	No	0	7	6
68	G.S4.03	G.S5.05	2.63727	Yes	Yes	3	7	9
69	G.S4.04	G.S4.06	2.65535	Yes	Yes	0	9	7
70	G.H3.08	G.S4.04	4.02735	No	Yes	0	9	9
71	G.H3.09	G.S4.04	12.1562	Yes	Yes	0	9	9
72	G.H3.05	G.S4.06	3.34621	No	Yes	0	9	7
73	G.S4.06	G.S5.06	2.9256	Yes	Yes	0	7	8
74	G.H4.15	G.S4.06	6.22107	Yes	Yes	0	8	7
75	G.S5.06	G.s4h3.01	4.96371	Yes	No	0	8	7
76	G.HG.04	G.s4h3.01	9.0776	Yes	No	0	8	7
77	G.HG.03	G.s4h3.02	3.8168	No	No	20	6	9
78	G.H3.01	G.s4h3.05	4.03811	Yes	No	0	8	8
79	G.HG.07	G.s4h3.04	6.42085	No	No	0	9	8
80	G.HG.17	G.s4h3.04	2.6481	No	No	0	3	8
81	G.H3.06	G.H4.15	5.75209	No	Yes	0	7	8
82	G.H3.06	G.h4s6.01	5.42402	No	No	0	7	4
83	G.H3.09	G.S5.02	4.97794	Yes	No	0	9	6
84	G.H3.09	G.S5.04	3.07998	Yes	Yes	9	9	9
85	G.H3.09	G.H4.15	7.8584	Yes	Yes	9	9	8
86	G.H3.10	G.H3.14	3.6709	No	No	21	4	8
87	G.H3.10	G.h4s6.01	10.5216	No	No	0	4	4
88	G.H3.10	G.h4s6.03	2.42161	No	No	21	4	4
89	G.H3.13	G.H3.14	2.60551	No	No	0	5	8
90	G.H3.13	G.h4s6.11	4.284	No	No	0	5	8
91	G.H3.14	G.h4s6.03	7.88144	No	No	21	8	4
92	G.H3.15	G.H3.18	3.70874	No	Yes	0	8	9
93	G.H3.16	G.H3.17	6.19113	No	Yes	0	4	4
94	G.H3.18	G.h3s5.03	7.24655	Yes	No	19	9	8
95	G.h3s5.01	G.h3s5.02	2.99889	No	No	0	2	4
96	G.H5.14	G.S5.01	7.77757	No	No	0	6	7
97	G.S5.03	G.S5.05	3.24394	No	Yes	0	8	9
98	G.H5.10	G.S5.03	3.28416	No	No	0	7	8
99	G.S5.04	G.S5.06	3.47373	Yes	Yes	0	9	8
100	G.H4.15	G.S5.04	4.18571	Yes	Yes	9	8	9
101	G.S5.04	G.S6.03	4.14837	Yes	No	9	9	4
102	G.S5.05	G.S6.04	2.74575	Yes	No	3	9	8
103	G.H5.03	G.S5.05	5.31444	No	Yes	3	8	9
104	G.H5.07	G.S5.05	3.26172	No	Yes	3	8	9
105	G.S5.06	G.S6.05	3.55215	Yes	No	0	8	5
106	G.S5.07	G.s6h5.01	4.77532	Yes	Yes	3	9	9
107	G.HG.03	G.s5hg.01	3.99836	No	Yes	20	6	9
108	G.HG.01	G.S6.05	5.20686	No	No	0	5	5
109	G.HG.01	G.s6h5.02	7.22225	No	No	0	5	7
110	G.HG.02	G.s6h5.02	2.65	No	No	0	9	7
111	G.H4.01	G.HG.14	2.97136	No	No	0	3	5
112	G.HG.15	G.hgh4.05	2.90298	No	Yes	0	7	6
113	G.H4.10	G.hgh4.02	4.81672	No	Yes	13	6	8
114	G.H4.14	G.hgh4.02	5.14793	No	Yes	13	6	8
115	G.hgh4.05	G.hgh4.07	5.26248	Yes	No	0	6	8
116	G.H4.05	G.hgh4.05	2.35551	Yes	Yes	0	4	6
117	G.H4.10	G.hgh4.05	7.88702	No	Yes	0	6	6
118	G.hgh4.07	G.hgh4.08	4.06	No	No	0	8	1
119	G.H4.05	G.hgh4.08	9.73155	Yes	No	0	4	1
120	G.H4.03	G.H4.04	4.70523	Yes	No	0	3	4
121	G.H4.10	G.H4.14	11.1204	No	No	13	6	6
122	G.H4.11	G.H4.15	2.39163	No	Yes	0	8	8
123	G.H4.12	G.H4.16	4.24348	No	Yes	9	5	3
124	G.H4.12	G.S6.03	8.11555	No	No	9	5	4
125	G.H4.16	G.S6.03	2.91679	Yes	No	9	3	4
126	G.h4s6.02	G.h4s6.11	5.83136	No	No	0	7	8
127	G.S6.01	G.h4s6.02	5.04283	Yes	No	0	5	7
128	G.h4s6.08	G.h4s6.09	4.02619	No	No	0	5	4
129	G.H5.21	G.h4s6.10	3.5933	Yes	No	0	4	3
130	G.S6.02	G.h4s6.12	10.8051	Yes	No	0	8	4
131	G.H5.10	G.S6.02	3.86975	No	Yes	0	7	8
132	G.H5.13	G.S6.02	7.94286	Yes	Yes	23	7	8
133	G.H5.06	G.S6.04	14.5402	No	No	3	3	8
134	G.H5.05	G.H5.09	5.64575	Yes	No	0	5	4
135	G.H5.16	I2x50	2.88454	No	No	0	7	9
136	G.H5.18	G.H5.21	2.52106	No	Yes	0	4	4
137	3x53	G.H5.19	3.4205	No	No	0	9	8
138	G.H5.20	G.H5.25	3.03916	No	No	0	8	6
139	3x54	G.H5.20	2.95642	No	No	0	8	8
140	G.H5.21	G.H5.26	3.45041	Yes	Yes	0	4	5
141	3x50	G.H5.23	4.77753	Yes	No	0	9	4
142	6x29	G.H5.26	7.91779	No	Yes	0	8	5
143	b.1x11	g.h1x12	3.90548	Yes	No	0	8	6
144	b.1x12	g.h1x11	3.3314	No	No	0	6	9
145	b.1x13	b.1x16	5.31573	No	No	0	1	4
146	b.1x15	b.1x19	3.79582	No	No	0	7	6
147	b.1x18	g.l1x4	2.93055	No	Yes	0	4	8
148	b.1x22	g.l1x4	2.78095	No	Yes	0	3	8
149	b.h2x2	b.lh12x4	2.61841	No	No	0	1	3
150	b.h2x3	b.lh12x4	5.50579	No	No	0	1	3
151	b.b21x5	b.h2x1	4.42692	Yes	No	0	4	5
152	b.h2x1	g.h2x5	2.5401	No	No	0	5	6
153	b.lhb1x4	b.lhb1x5	2.67056	No	No	0	1	1
154	b.l24x3	b.lhb1x5	2.49509	Yes	No	0	5	1
155	b.lhb1x6	b.lhb1x9	2.37271	Yes	No	0	3	3
156	b.l22x5	b.lhb1x6	3.99756	Yes	Yes	8	9	3
157	b.b24x7	b.lhb1x6	5.5325	Yes	Yes	8	9	3
158	b.lhb1x6	g.ctx6	2.39583	Yes	Yes	8	3	6
159	b.lhb1x10	b.lhb1x8	5.88152	No	No	0	4	2
160	b.b25x7	b.lhb1x11	3.90899	No	No	0	7	4
161	b.lhb1x11	g.ctx5	3.64457	No	No	0	4	9
162	b.b1x1	b.b1x3	7.94426	No	No	0	5	7
163	b.b1x2	b.b28x4	6.78139	No	Yes	10	3	6
164	b.b1x2	b.b28x6	8.77093	No	Yes	10	3	9
165	b.b1x3	b.b28x7	5.31152	No	No	0	7	9
166	b.b1x4	b.b5x1	4.17683	No	No	0	7	5
167	b.b1x4	b.b28x5	3.16576	No	No	4	7	5
168	b.b1x4	g.ctx16	5.30909	No	Yes	4	7	8
169	b.b1x5	b.l1x1	7.34449	No	No	0	3	7
170	b.b1x5	b.b28x4	4.6001	No	Yes	0	3	6
171	b.b1x6	b.b4x6	15.6011	No	Yes	0	9	9
172	b.b1x6	b.b5x1	3.68634	No	No	0	9	5
173	b.b1x6	b.b28x3	6.81789	No	No	0	9	7
174	b.b28x2	b.l1x1	7.88054	No	No	0	4	7
175	b.l1x3	b.l1x7	8.09258	Yes	No	0	9	9
176	b.b3x4	b.l1x3	6.45675	No	Yes	4	9	9
177	b.b3x6	b.l1x3	11.3424	No	Yes	4	9	9
178	b.b4x4	b.l1x3	10.8709	No	Yes	4	8	9
179	b.b4x6	b.l1x3	2.59555	Yes	Yes	4	9	9
180	b.l1x4	b.l3x2	3.25483	No	Yes	0	6	9
181	b.b2x1	b.l1x6	6.4414	Yes	No	12	8	9
182	b.l1x6	b.l28x1	21.565	No	Yes	12	9	9
183	b.b28x3	b.l1x7	2.67119	No	No	0	7	9
184	b.b2x1	b.l3x1	13.7444	Yes	No	0	8	9
185	b.b2x3	b.b2x5	3.82666	Yes	Yes	4	6	7
186	b.b26x2	b.b2x3	4.536	No	Yes	0	7	6
187	b.b2x4	b.b6x5	2.55977	No	Yes	0	6	6
188	b.b10x4	b.b2x4	12.2743	No	No	0	6	6
189	b.b2x5	b.b3x2	8.72213	Yes	No	4	7	5
190	b.b2x5	b.l4x1	4.94311	Yes	No	4	7	5
191	b.b2x5	b.l27x1	12.2559	Yes	Yes	4	7	7
192	b.b27x2	b.b2x5	4.03857	No	Yes	0	5	7
193	b.b6x5	b.l2x1	4.21485	Yes	No	0	6	5
194	b.l2x3	b.l2x5	4.15694	No	No	0	8	5
195	b.l27x1	b.l2x4	5.66666	Yes	No	4	7	5
196	b.l27x3	b.l2x4	8.45971	No	No	4	7	5
197	b.b4x7	b.l2x5	13.9365	Yes	No	0	8	5
198	b.l2x5	b.l4x2	23.5592	No	Yes	0	5	4
199	b.b3x1	b.b6x5	3.37629	No	Yes	0	5	6
200	b.b3x2	b.b4x6	5.42066	No	Yes	4	5	9
201	b.b3x3	b.b4x3	3.15502	No	Yes	0	8	7
202	b.b3x3	b.b4x5	3.33444	No	Yes	0	8	7
203	b.b3x3	b.b6x5	6.3875	No	Yes	0	8	6
204	b.b3x4	b.b4x6	4.96313	No	Yes	4	9	9
205	b.b28x3	b.b3x4	3.54783	No	No	0	7	9
206	b.b3x5	b.l5x6	2.36772	No	No	0	9	9
207	b.b3x5	b.b6x3	2.52489	No	No	0	9	8
208	b.b3x6	b.l3x2	8.89744	No	Yes	4	9	9
209	b.l3x1	b.l5x5	4.42536	No	Yes	0	9	9
210	b.b4x2	b.l3x2	5.39662	No	Yes	0	8	9
211	b.b4x3	b.b5x7	3.91506	Yes	Yes	0	7	7
212	b.b4x3	b.l5x1	4.08154	Yes	Yes	14	7	8
213	b.b4x3	b.b7x4	3.80164	Yes	Yes	14	7	8
214	b.b4x4	b.b4x6	13.0116	No	Yes	4	8	9
215	b.b4x4	b.b5x3	3.1373	No	Yes	4	8	9
216	b.b4x5	b.b5x4	2.85851	Yes	No	17	7	5
217	b.b4x5	b.b5x5	5.73921	Yes	Yes	17	7	5
218	b.b4x5	b.l8x1	3.10331	Yes	No	0	7	5
219	b.b4x6	b.b5x3	9.59946	Yes	Yes	4	9	9
220	b.b4x7	b.l4x3	8.1374	Yes	No	18	8	6
221	b.l4x1	b.l4x2	2.52278	No	Yes	4	5	4
222	b.l4x1	g.ctx16	3.14175	No	Yes	4	5	8
223	b.l4x2	g.ctx15	8.62631	Yes	Yes	4	4	9
224	b.l4x2	g.ctx16	5.20038	Yes	Yes	4	4	8
225	b.b5x2	b.l4x3	9.31244	Yes	No	18	7	6
226	b.b5x4	b.b5x5	6.20929	No	Yes	17	5	5
227	b.b5x5	b.l8x8	3.29281	Yes	No	0	5	4
228	b.b5x7	b.b5x8	3.39	Yes	No	0	7	5
229	b.b5x7	b.b8x4	4.5226	Yes	Yes	0	7	6
230	b.b5x7	b.l8x8	5.40684	Yes	No	0	7	4
231	b.l5x1	b.l5x6	3.81369	Yes	No	14	8	9
232	b.b7x4	b.l5x1	3.46917	Yes	Yes	14	8	8
233	b.b8x4	b.l5x1	4.26602	Yes	Yes	14	6	8
234	b.b9x3	b.l5x2	3.47643	No	No	0	6	6
235	b.l5x3	b.l7x3	7.88777	No	No	0	8	9
236	b.l5x5	b.l7x2	4.59499	Yes	No	2	9	9
237	b.b6x1	b.l7x2	3.80718	No	No	2	9	9
238	b.b6x1	b.l9x6	3.68004	No	Yes	2	9	8
239	b.b6x5	b.l6x4	2.72528	Yes	No	0	6	5
240	b.b6x5	b.b7x2	2.83438	Yes	No	0	6	8
241	b.b10x5	b.l6x1	6.00093	Yes	No	0	9	6
242	b.l6x3	b.l6x5	7.59427	No	Yes	15	6	4
243	b.l10x3	b.l6x3	8.48971	No	No	15	6	6
244	b.b7x1	b.l6x5	3.36419	Yes	Yes	15	4	4
245	b.l6x5	b.l8x2	6.76869	Yes	No	0	4	4
246	b.l10x3	b.l6x5	2.56591	No	Yes	15	6	4
247	b.b7x1	b.b8x3	3.22859	Yes	No	0	4	6
248	b.b7x1	b.b8x5	9.28848	Yes	No	0	4	4
249	b.b7x1	b.l10x3	5.68611	Yes	No	15	4	6
250	b.b7x2	b.l8x1	3.2307	No	No	0	8	5
251	b.b10x5	b.b7x3	3.74741	Yes	No	0	9	9
252	b.b7x4	b.b8x4	2.56628	Yes	Yes	14	8	6
253	b.l7x2	b.l9x6	2.89805	No	Yes	2	9	8
254	b.l7x3	b.l7x5	5.17429	No	No	0	9	6
255	b.l7x4	b.l9x5	4.34504	Yes	No	0	9	8
256	b.b9x3	b.l7x5	4.9589	No	No	0	6	6
257	b.l7x5	b.l9x1	3.76683	No	No	0	6	5
258	b.b8x1	b.l9x7	2.86917	No	No	0	8	7
259	b.b10x3	b.b8x1	2.36167	No	No	0	8	8
260	b.b8x2	b.b9x3	3.95378	No	No	0	8	6
261	b.b10x5	b.b8x3	2.76683	Yes	No	0	9	6
262	b.b8x3	b.l12x1	3.23015	No	No	0	6	6
263	b.b8x4	b.l8x10	5.40772	Yes	No	0	6	4
264	b.l8x1	b.l8x8	3.56417	No	No	0	5	4
265	b.l8x3	b.l8x5	2.95814	No	Yes	16	3	3
266	b.l8x3	b.l8x9	3.96771	No	No	16	3	3
267	b.l8x5	b.l8x7	5.31647	Yes	No	16	3	3
268	b.l8x5	b.l8x9	4.65749	Yes	No	16	3	3
269	b.l8x7	b.l8x9	2.52649	No	No	16	3	3
270	b.b12x6	b.b9x4	13.7788	Yes	No	0	8	9
271	b.b12x6	b.l9x2	2.53076	Yes	No	0	8	5
272	b.l9x3	b.l9x7	2.55963	Yes	No	2	9	7
273	b.b11x4	b.l9x3	5.3972	No	Yes	2	9	9
274	b.b11x6	b.l9x3	14.9023	No	Yes	2	9	9
275	b.l11x2	b.l9x3	4.43132	Yes	Yes	2	9	9
276	b.b12x6	b.l9x3	3.4917	Yes	Yes	2	8	9
277	b.l11x2	b.l9x4	9.15714	Yes	No	0	9	5
278	b.l11x1	b.l9x6	5.62848	No	Yes	2	9	8
279	b.l13x6	b.l9x6	7.19699	Yes	Yes	2	9	8
280	b.b14x1	b.l9x6	3.41957	No	Yes	2	8	8
281	b.b11x4	b.l9x7	4.23821	No	No	2	9	7
282	b.b10x2	b.b14x3	4.03429	No	Yes	0	6	5
283	b.b10x4	b.b14x5	2.74285	No	No	0	6	5
284	b.b10x5	b.b11x2	6.62396	Yes	No	0	9	7
285	b.b11x1	b.l10x1	4.91016	No	No	0	5	3
286	b.b14x5	b.l10x1	4.34383	No	No	0	5	3
287	b.l10x1	b.l14x4	2.42183	No	No	0	3	1
288	b.b11x1	b.l10x2	5.18108	No	No	0	5	5
289	b.l10x4	b.l12x1	2.65934	No	No	0	3	6
290	b.l10x4	b.l12x2	8.60305	No	No	24	3	6
291	b.b11x1	b.b12x5	3.1255	No	No	0	5	6
292	b.b11x2	b.b12x6	3.16212	No	Yes	0	7	8
293	b.b11x2	b.l12x1	3.67597	No	No	0	7	6
294	b.b11x3	b.b14x3	2.61341	No	Yes	5	5	5
295	b.b11x3	b.b15x1	3.86533	No	Yes	5	5	9
296	b.b11x4	b.b12x6	7.11784	No	Yes	2	9	8
297	b.b11x5	b.l13x7	5.34004	No	No	0	6	9
298	b.b11x5	b.b14x3	5.01956	No	Yes	0	6	5
299	b.b11x6	b.l11x1	3.33266	No	No	2	9	9
300	b.b11x6	b.l11x2	6.25894	No	Yes	2	9	9
301	b.l11x1	b.l13x6	5.38777	No	Yes	2	9	9
302	b.b12x2	b.l11x2	7.41691	No	Yes	0	7	9
303	b.b12x3	b.b13x7	4.18905	No	Yes	5	8	7
304	b.b12x4	b.b12x6	3.07821	No	Yes	2	4	8
305	b.b12x4	b.b13x3	5.72155	No	No	2	4	4
306	b.b12x5	b.b13x4	3.48091	No	No	5	6	4
307	b.b12x6	b.b13x3	13.3289	Yes	No	2	8	4
308	b.b12x7	b.l12x2	2.72496	No	No	24	9	6
309	b.b12x7	b.l12x3	9.47662	No	No	0	9	5
310	b.b13x2	b.l12x3	3.45677	No	No	0	4	5
311	b.b13x4	b.b13x5	2.44721	No	No	5	4	4
312	b.b13x5	b.b13x7	4.88897	No	Yes	5	4	7
313	b.b13x7	b.b15x1	8.67657	Yes	Yes	5	7	9
314	b.b13x7	b.b16x6	14.1796	Yes	Yes	5	7	8
315	b.b13x7	b.b17x1	3.43424	Yes	No	0	7	4
316	b.l13x3	b.l13x7	4.87025	Yes	No	5	9	9
317	b.b15x3	b.l13x3	5.13506	No	Yes	5	9	9
318	b.b15x5	b.l13x3	6.53593	No	Yes	5	8	9
319	b.b16x4	b.l13x3	14.8228	Yes	Yes	5	6	9
320	b.b16x6	b.l13x3	3.06783	Yes	Yes	5	8	9
321	b.l13x4	b.l15x2	6.01191	No	Yes	0	3	9
322	b.l13x6	b.l15x1	2.73433	Yes	Yes	2	9	7
323	b.b14x1	b.l15x1	3.915	No	Yes	2	8	7
324	b.b14x2	b.b18x3	4.00992	No	Yes	0	7	8
325	b.b14x3	b.b15x1	4.13561	Yes	Yes	5	5	9
326	b.b14x4	b.b18x5	5.66872	No	No	0	8	5
327	b.b18x5	b.l14x1	4.15783	No	No	0	5	4
328	b.l14x2	b.l18x4	3.54444	No	No	0	4	7
329	b.l14x3	b.l14x5	7.68484	No	No	0	5	5
330	b.l14x5	b.l16x2	6.47068	No	No	0	5	9
331	b.b16x5	b.l14x6	4.35321	Yes	No	0	5	3
332	b.b15x1	b.b16x6	11.3932	Yes	Yes	5	9	8
333	b.b15x2	b.b16x5	3.71317	Yes	Yes	0	6	5
334	b.b15x2	b.b18x3	5.2375	Yes	Yes	6	6	8
335	b.b15x2	b.b18x5	8.58427	Yes	No	0	6	5
336	b.b15x2	b.b19x2	6.30692	Yes	Yes	6	6	6
337	b.b15x3	b.b16x6	5.66745	No	Yes	5	9	8
338	b.b15x4	b.l17x7	3.2691	No	No	0	6	7
339	b.b15x5	b.l15x2	2.43684	No	Yes	5	8	9
340	b.l15x1	b.l17x6	8.88994	Yes	No	2	7	9
341	b.b16x2	b.l15x2	8.33149	No	Yes	0	5	9
342	b.b16x4	b.b16x6	6.76575	Yes	Yes	5	6	8
343	b.b16x4	b.b17x3	4.33107	Yes	No	5	6	5
344	b.b16x4	b.b17x6	10.9306	Yes	No	0	6	7
345	b.b16x5	b.b17x5	2.89376	Yes	Yes	0	5	7
346	b.b16x5	b.l20x1	5.19192	Yes	No	0	5	6
347	b.b16x6	b.b17x3	6.14075	Yes	No	5	8	5
348	b.b16x7	b.l16x3	9.94095	No	No	0	9	3
349	b.b16x7	b.b17x4	8.42117	No	No	0	9	5
350	b.b17x2	b.l16x3	5.83508	No	No	0	3	3
351	b.b17x3	g.h1x10	4.7351	No	No	0	5	9
352	b.b17x5	b.b17x7	8.31994	Yes	Yes	6	7	8
353	b.b17x5	b.b21x1	10.8414	Yes	Yes	6	7	7
354	b.b17x6	g.h1x14	6.83077	No	No	0	7	9
355	b.b17x7	b.b19x2	8.89655	Yes	Yes	6	8	6
356	b.b17x7	b.b20x6	8.53798	Yes	Yes	6	8	6
357	b.b17x7	b.b21x1	3.43837	Yes	Yes	6	8	7
358	b.l17x3	b.l17x7	6.04348	Yes	No	6	9	7
359	b.b19x6	b.l17x3	11.837	No	Yes	6	9	9
360	b.b20x4	b.l17x3	11.8413	Yes	Yes	6	8	9
361	b.l17x4	b.l19x2	5.34622	No	Yes	0	3	9
362	b.l17x5	b.l19x2	4.00558	No	Yes	0	6	9
363	b.b19x4	b.l17x7	3.72279	Yes	No	6	8	7
364	b.b18x1	b.l19x1	7.6894	No	No	0	9	9
365	b.b18x2	b.b22x3	2.5897	No	No	0	5	6
366	b.b18x3	b.b19x2	4.14514	Yes	Yes	6	8	6
367	b.b18x3	b.b19x4	4.62997	Yes	Yes	6	8	8
368	b.l18x1	b.l18x2	9.89254	Yes	Yes	11	6	7
369	b.b19x1	b.l18x1	2.66299	No	Yes	0	6	6
370	b.b22x5	b.l18x1	8.32402	Yes	Yes	11	7	6
371	b.l18x1	b.l22x4	3.41968	Yes	No	11	6	9
372	b.l18x1	g.h2x8	4.64098	Yes	No	0	6	7
373	b.l18x1	g.h2x11	3.77438	Yes	Yes	11	6	6
374	b.l18x2	g.h2x11	5.02055	Yes	Yes	11	7	6
375	b.l18x3	b.l18x5	8.77528	No	No	0	5	2
376	b.b19x2	b.b20x6	10.5289	Yes	Yes	6	6	6
377	b.b19x3	b.b22x5	2.88252	No	Yes	0	4	7
378	b.b19x4	b.b20x6	6.3001	Yes	Yes	6	8	6
379	b.b19x5	b.l21x9	4.11328	No	No	0	5	6
380	b.b19x6	b.l19x2	6.65309	No	Yes	6	9	9
381	b.b20x2	b.l19x2	7.53738	No	Yes	0	6	9
382	b.b20x2	b.b20x4	5.37426	No	Yes	0	6	8
383	b.b20x3	b.b21x7	3.56396	No	Yes	0	8	5
384	b.b20x3	b.l21x9	4.16925	No	No	0	8	6
385	b.b20x4	b.b20x6	3.352	Yes	Yes	6	8	6
386	b.b20x4	b.b21x3	15.8093	Yes	Yes	6	8	6
387	b.b20x4	b.b21x6	9.75817	Yes	No	6	8	1
388	b.b20x5	b.b21x4	2.55129	No	No	0	7	5
389	b.b20x5	b.b21x7	5.54294	No	Yes	0	7	5
390	b.b20x6	b.b21x3	5.81575	Yes	Yes	6	6	6
391	b.b20x7	b.l20x3	2.58217	No	No	0	9	7
392	b.b20x7	b.b21x4	8.49968	No	No	0	9	5
393	b.b20x7	g.h2x4	3.38046	No	No	0	9	7
394	b.l20x2	g.l1x5	6.32635	No	No	0	9	4
395	b.b21x3	b.b21x6	4.00492	Yes	No	6	6	1
396	b.b21x4	g.h2x1	2.69974	No	No	0	5	8
397	b.b21x5	b.b21x7	9.5869	Yes	Yes	7	4	5
398	b.b21x5	b.b25x1	3.3235	Yes	No	7	4	2
399	b.b21x7	b.b23x2	3.78929	Yes	No	0	5	6
400	b.b21x7	b.b24x6	7.98349	Yes	Yes	7	5	8
401	b.b21x7	b.b25x1	2.55345	Yes	No	7	5	2
402	b.l21x2	b.l21x4	6.53398	Yes	No	0	4	4
403	b.l21x2	b.l21x5	3.05333	Yes	No	0	4	4
404	b.b23x6	b.l21x5	5.69494	Yes	No	0	7	4
405	b.l21x7	b.l23x2	5.91502	No	No	0	5	8
406	b.b23x6	b.l21x9	8.71124	Yes	No	0	7	6
407	b.b22x2	b.b26x3	4.28367	No	No	0	8	6
408	b.b22x4	b.b26x5	4.34461	No	No	0	5	7
409	b.b22x5	b.b23x2	8.60383	Yes	No	0	7	6
410	b.l22x1	g.ctx3	7.34046	No	Yes	0	9	9
411	b.l22x1	g.ctx5	3.67386	No	No	0	9	9
412	b.l22x3	g.ctx3	10.3726	No	Yes	0	9	9
413	b.b24x7	b.l22x5	11.7016	Yes	Yes	8	9	9
414	b.l22x5	b.l24x2	7.22418	Yes	No	8	9	6
415	b.l22x5	g.h2x12	4.24834	Yes	No	8	9	7
416	b.l22x5	g.ctx6	3.63848	Yes	Yes	8	9	6
417	b.b23x1	b.b24x5	4.26542	No	No	0	5	5
418	b.b23x1	g.ctx6	2.51882	No	Yes	0	5	6
419	b.b23x3	b.b24x5	3.8267	No	No	0	7	5
420	b.b23x3	b.b27x1	4.08331	No	No	0	7	6
421	b.b23x4	b.b23x6	3.79194	No	Yes	0	6	7
422	b.b23x5	b.l25x7	2.71035	No	No	0	7	7
423	b.b23x6	b.b24x4	10.0103	Yes	Yes	7	7	6
424	b.b23x6	b.b24x6	6.96063	Yes	Yes	7	7	8
425	b.l23x1	b.l25x6	15.4212	Yes	No	0	6	8
426	b.b24x2	b.l23x2	5.45107	Yes	No	0	5	8
427	b.b24x1	b.l25x5	2.90106	No	No	0	4	7
428	b.b24x2	b.b25x6	4.06314	Yes	Yes	7	5	3
429	b.b24x3	b.b25x7	4.80685	No	No	0	5	7
430	b.b24x4	b.b24x6	3.56488	Yes	Yes	7	6	8
431	b.b24x4	b.b25x3	11.2521	Yes	Yes	7	6	5
432	b.b24x4	b.b25x6	3.65817	Yes	Yes	7	6	3
433	b.b24x6	b.b25x3	6.05063	Yes	Yes	7	8	5
434	b.b24x7	b.l24x3	8.85926	Yes	Yes	8	9	5
435	b.l24x2	g.h2x12	3.06556	No	No	8	6	7
436	b.b25x2	b.l24x3	5.87604	No	Yes	8	2	5
437	b.b25x3	b.b25x6	2.8281	Yes	Yes	7	5	3
438	b.b25x7	b.b28x6	11.6233	No	Yes	0	7	9
439	b.l25x3	b.l25x7	2.84428	Yes	No	0	9	7
440	b.b27x3	b.l25x3	6.29825	No	Yes	0	8	9
441	b.b27x5	b.l25x3	13.5276	No	Yes	10	9	9
442	b.l25x3	b.l28x2	9.02909	Yes	Yes	10	9	9
443	b.b28x4	b.l25x3	10.872	Yes	Yes	10	6	9
444	b.l25x4	b.l28x2	5.68304	No	Yes	0	5	9
445	b.l25x6	b.l28x1	16.4572	No	Yes	0	8	9
446	b.b26x1	b.l28x1	5.44397	No	Yes	0	9	9
447	b.b26x3	b.b27x3	3.3455	No	No	0	6	8
448	b.b26x5	b.b27x1	2.86751	No	No	0	7	6
449	b.l27x1	b.l27x3	6.2417	Yes	No	4	7	7
450	b.l27x3	b.l27x5	6.35698	No	No	0	7	5
451	b.l27x5	g.ctx4	4.97483	No	No	0	5	7
452	b.l27x5	g.ctx15	5.86721	No	Yes	0	5	9
453	b.l27x6	g.ctx16	4.48587	No	Yes	0	7	8
454	b.b27x3	b.b28x6	7.37274	No	Yes	0	8	9
455	b.b27x5	b.l28x2	7.36073	No	Yes	10	9	9
456	b.b28x2	b.l28x2	5.69933	No	Yes	0	4	9
457	b.b28x1	b.b28x2	2.84094	No	No	0	4	4
458	b.b28x4	b.b28x6	6.69578	Yes	Yes	10	6	9
459	b.b28x5	g.ctx16	4.89176	No	Yes	4	5	8
460	b.b28x7	g.ctx14	8.97213	No	No	0	9	9
461	b.b28x7	g.ctx16	3.58813	No	Yes	0	9	8
462	g.h1x1	g.h1x5	3.93001	No	Yes	0	2	6
463	g.h1x10	g.h1x14	5.8405	No	No	0	9	9
464	g.l1x2	g.l1x4	4.14733	No	Yes	0	2	8
465	g.h2x3	g.l1x5	3.15366	No	No	0	5	4
466	g.h2x11	g.h2x15	13.7273	Yes	No	0	6	6
467	g.ctx3	g.ctx4	4.49267	Yes	No	0	9	7
468	g.ctx3	g.ctx6	7.46142	Yes	Yes	0	9	6
469	g.ctx10	g.ctx9	3.28721	No	No	0	5	6
470	g.ctx12	g.ctx13	3.46637	No	No	0	6	5
471	g.ctx14	g.ctx15	5.1552	No	Yes	0	9	9
472	g.ctx15	g.ctx16	4.43643	Yes	Yes	4	9	8
473	1x46	7x47	2.39211	No	No	0	8	8
474	1x50	2x50	10.2755	No	Yes	1	9	9
475	1x50	2x51	3.00905	No	No	0	9	8
476	1x50	7x50	6.88529	No	No	1	9	9
477	1x52	8x54	5.9963	No	No	0	8	8
478	1x56	8x54	3.03215	No	No	0	9	8
479	8x50	I1x50	3.96894	Yes	No	0	8	9
480	2x37	2x40	3.74519	No	No	0	8	9
481	2x41	4x42	2.37909	No	No	0	8	8
482	2x42	3x46	4.20955	Yes	No	0	8	9
483	2x42	4x42	3.71789	Yes	No	0	8	8
484	2x42	4x45	2.80948	Yes	No	0	8	7
485	2x42	4x46	2.83693	Yes	No	0	8	8
486	2x43	7x53	2.87838	No	Yes	0	8	9
487	2x45	3x42	5.67102	No	No	0	9	8
488	2x45	4x46	6.69299	No	No	0	9	8
489	2x45	4x50	3.44821	No	No	0	9	9
490	2x46	3x42	3.89925	Yes	No	0	9	8
491	2x46	3x43	3.40167	Yes	No	1	9	8
492	2x46	7x49	3.14723	Yes	Yes	1	9	9
493	2x50	7x46	5.234	Yes	No	0	9	9
494	2x50	7x50	2.64117	Yes	No	1	9	9
495	2x52	3x35	6.01544	No	No	0	8	7
496	2x53	3x35	4.4259	Yes	No	0	8	7
497	2x53	7x46	3.66221	Yes	No	0	8	9
498	2x551	3x31	2.65895	No	No	0	7	7
499	2x56	3x32	4.21483	No	Yes	1	8	8
500	2x56	7x42	2.53293	No	Yes	1	8	8
501	2x57	7x42	4.58904	Yes	Yes	0	8	8
502	2x59	3x28	8.07214	No	No	0	7	7
503	2x63	E1x50	4.71264	No	Yes	0	8	8
504	2x64	7x35	2.39496	No	No	0	7	7
505	E1x50	E1x52	6.14779	Yes	Yes	0	8	7
506	3x25	E1x50	5.99664	No	Yes	1	9	8
507	E1x50	E2x50	8.99929	Yes	No	1	8	9
508	E1x51	E1x52	3.351	No	Yes	0	5	7
509	3x24	E1x52	5.46958	No	Yes	0	6	7
510	3x25	E2x50	6.71956	No	No	1	9	9
511	3x28	3x29	2.43734	No	No	0	7	7
512	3x29	E2x50	2.64437	No	No	0	7	9
513	3x32	7x42	5.36489	Yes	Yes	1	8	8
514	3x32	Lig	5.1264	Yes	Yes	1	8	0
515	3x33	4x57	3.86988	No	No	0	8	8
516	3x33	Lig	3.94025	No	Yes	1	8	0
517	3x34	4x53	3.05356	No	No	0	7	8
518	3x34	4x57	4.63964	No	No	0	7	8
519	3x36	6x48	2.94307	No	Yes	1	7	9
520	3x36	Lig	3.72214	No	Yes	1	7	0
521	3x37	3x41	3.06657	No	No	0	8	7
522	3x38	4x50	10.0311	No	No	0	8	9
523	3x38	4x53	2.88852	No	No	0	8	8
524	3x40	6x48	4.98767	No	Yes	0	9	9
525	3x41	4x49	3.20729	No	No	0	7	8
526	3x42	4x49	2.81746	No	No	0	8	8
527	3x43	7x49	5.55705	No	Yes	1	8	9
528	3x43	7x53	4.90294	No	Yes	1	8	9
529	3x46	3x50	3.32591	No	Yes	1	9	9
530	3x47	5x58	6.41728	No	Yes	0	9	8
531	3x49	I2x57	3.87608	Yes	No	0	9	7
532	3x51	3x55	9.35696	Yes	No	0	8	7
533	3x52	I2x53	5.29183	No	No	0	6	9
534	3x55	3x56	2.91987	No	No	0	7	7
535	I2x53	I2x57	3.81508	No	No	0	9	7
536	4x38	4x40	2.40016	No	No	0	8	5
537	5x36	E2	7.61191	No	Yes	1	5	7
538	5x47	6x52	12.9917	Yes	Yes	1	8	8
539	5x54	5x58	3.07742	No	Yes	0	8	8
540	6x36	7x56	4.2239	No	No	0	8	8
541	6x40	7x53	4.59053	No	Yes	0	8	9
542	6x44	6x48	6.5172	No	Yes	1	9	9
543	6x44	7x45	2.69829	No	Yes	1	9	9
544	6x45	6x49	2.70563	No	Yes	0	7	7
545	6x47	7x45	9.13656	No	Yes	0	8	9
546	6x48	6x52	3.87736	Yes	Yes	1	9	8
547	6x48	7x41	3.36206	Yes	No	0	9	8
548	6x48	7x45	8.65636	Yes	Yes	1	9	9
549	6x49	6x50	3.18341	Yes	No	0	7	9
550	6x50	7x37	3.99779	No	No	0	9	7
551	6x51	6x52	4.25506	Yes	Yes	1	8	8
552	6x51	6x55	3.485	Yes	No	1	8	8
553	6x51	7x38	3.25679	Yes	Yes	1	8	7
554	6x51	Lig	5.89549	Yes	Yes	1	8	0
555	6x54	7x34	3.29863	No	No	0	7	6
556	6x54	7x37	5.31003	No	No	0	7	7
557	6x55	Lig	4.00245	No	Yes	1	8	0
558	7x38	7x42	4.56389	Yes	Yes	1	7	8
559	7x38	Lig	4.58808	Yes	Yes	1	7	0
560	7x42	Lig	2.68876	Yes	Yes	1	8	0
561	7x45	7x49	6.77086	Yes	Yes	1	9	9
562	7x52	7x53	2.43115	No	Yes	0	8	9
563	7x54	8x50	6.89081	No	Yes	0	9	8
564	8x47	8x49	2.54691	No	No	0	9	8
565	8x47	8x50	2.64508	No	Yes	0	9	8
566	8x48	8x51	3.30141	No	No	0	6	9
567	8x48	8x52	3.04035	No	No	0	6	6
568	G.HN.40	b.b5x3	3.264	No	Yes	0	7	9
569	G.S1.01	G.S3.04	5.99891	No	No	0	6	6
570	G.H1.05	G.S2.04	2.9537	No	No	0	7	7
571	G.H1.07	G.H5.03	2.64314	No	No	0	9	8
572	G.H2.06	b.l15x1	4.49859	Yes	Yes	2	9	7
573	G.H2.06	b.b18x1	2.5985	Yes	No	0	9	9
574	G.H3.17	G.h2s4.02	5.15671	Yes	No	0	4	7
575	G.S4.05	G.S5.07	2.78592	No	Yes	3	7	9
576	G.S4.07	G.s5hg.01	5.16189	No	Yes	0	8	9
577	G.H4.11	G.s4h3.01	3.1226	No	No	0	8	7
578	G.H3.03	G.hgh4.01	2.77935	No	Yes	0	4	4
579	G.H3.09	G.H3.13	3.98409	Yes	No	0	9	5
580	G.S5.04	G.S6.01	2.35638	Yes	Yes	9	9	5
581	G.S5.05	G.s6h5.01	4.09348	Yes	Yes	3	9	9
582	G.H5.06	G.S5.05	2.55034	No	Yes	3	3	9
583	G.HG.04	G.HG.08	6.45501	Yes	No	0	8	7
584	G.H4.03	G.HG.04	3.62617	Yes	Yes	0	3	8
585	G.H4.03	G.HG.05	3.40714	Yes	No	0	3	4
586	G.hgh4.01	G.hgh4.02	5.3617	Yes	Yes	13	4	8
587	G.hgh4.03	G.hgh4.04	8.31129	No	No	0	6	5
588	G.H4.02	G.H4.05	2.65083	No	Yes	22	5	4
589	G.H4.16	G.S6.01	4.97676	Yes	Yes	9	3	5
590	G.H5.14	G.S6.02	5.0651	No	Yes	0	6	8
591	G.H5.03	G.s6h5.01	5.67999	No	Yes	3	8	9
592	G.H5.02	G.H5.05	2.706	No	Yes	0	4	5
593	5x68	G.H5.13	3.13466	No	Yes	0	7	7
594	b.1x13	b.1x9	4.74082	No	No	0	1	4
595	b.1x11	g.h1x11	4.72156	Yes	No	0	8	9
596	b.1x16	b.1x17	3.34882	No	No	0	4	2
597	b.1x19	b.b21x1	10.7629	No	Yes	0	6	7
598	b.1x19	b.b21x2	2.91112	No	Yes	0	6	6
599	b.b21x2	b.lh12x1	2.94939	Yes	No	0	6	3
600	b.lh12x2	g.l1x6	6.03911	No	No	0	8	4
601	b.l22x5	b.lhb1x3	3.15599	Yes	No	0	9	2
602	b.l24x3	b.lhb1x3	3.28746	Yes	No	0	5	2
603	b.l1x3	b.l3x2	5.62583	Yes	Yes	4	9	9
604	b.b2x1	b.l28x1	4.28437	Yes	Yes	12	8	9
605	b.b2x2	b.b6x3	2.36841	No	No	0	7	8
606	b.b2x3	b.b3x2	2.48685	Yes	No	4	6	5
607	b.b3x1	b.l2x3	3.62594	No	No	0	5	8
608	b.b3x1	b.b4x7	2.60844	No	Yes	0	5	8
609	b.b4x7	b.b5x2	3.20613	Yes	Yes	18	8	7
610	b.b7x4	b.l5x6	2.92802	Yes	No	14	8	9
611	b.b10x3	b.b6x2	4.67567	No	No	0	8	8
612	b.b10x5	b.b6x4	2.42452	Yes	No	0	9	7
613	b.b8x1	b.b9x4	2.57535	No	No	0	8	9
614	b.b8x2	b.b8x4	4.87444	No	Yes	0	8	6
615	b.b8x5	b.l8x3	4.54164	No	No	0	4	3
616	b.b10x1	b.l9x6	3.0526	No	Yes	0	9	8
617	b.b10x2	b.b10x4	3.21319	No	No	0	6	6
618	b.b12x7	b.l10x4	7.92957	No	No	24	9	3
619	b.b12x5	b.b13x5	2.67613	No	No	5	6	4
620	b.b13x3	b.b13x6	4.04967	No	No	0	4	4
621	b.l13x3	b.l15x2	4.175	Yes	Yes	5	9	9
622	b.b16x5	b.b17x4	3.01931	Yes	No	0	5	5
623	b.l16x2	b.l16x3	2.67647	No	No	0	9	3
624	b.b17x5	g.l1x2	3.09956	Yes	No	0	7	2
625	b.l17x3	b.l19x2	3.705	Yes	Yes	6	9	9
626	b.l17x6	b.l19x1	4.20783	No	No	0	9	9
627	b.l18x1	b.l18x3	4.66861	Yes	No	11	6	5
628	b.b22x5	b.l18x2	3.20355	Yes	Yes	11	7	7
629	b.l18x2	b.l22x4	3.78611	Yes	No	11	7	9
630	b.l18x3	g.h2x11	10.5894	No	Yes	11	5	6
631	b.l18x5	b.l20x2	6.73648	No	No	0	2	9
632	b.b20x2	b.l21x1	3.80378	No	No	0	6	2
633	b.l20x2	g.h2x7	6.25537	No	No	0	9	5
634	b.b21x1	g.l1x4	8.4878	Yes	Yes	0	7	8
635	b.b21x2	g.h2x1	3.57915	Yes	No	0	6	8
636	b.l21x7	b.l23x1	5.71171	No	Yes	0	5	6
637	b.b22x1	b.b22x2	3.72698	No	No	0	8	8
638	b.b22x1	b.l23x1	3.32628	No	Yes	0	8	6
639	b.b23x1	b.l22x1	2.79479	No	No	0	5	9
640	b.b23x6	b.l23x2	3.75467	Yes	No	0	7	8
641	b.b26x1	b.b26x2	3.57241	No	No	0	9	7
642	g.h1x12	g.h1x9	3.39643	No	No	0	6	6
643	g.ctx10	g.ctx13	3.73802	No	No	0	5	5
644	1x31	1x35	2.45427	No	Yes	0	5	6
645	1x53	8x50	2.88638	No	Yes	0	9	8
646	1x56	8x50	4.73708	No	Yes	0	9	8
647	1x57	8x50	3.86906	No	Yes	0	8	8
648	2x42	3x45	4.05692	Yes	No	0	8	8
649	2x42	3x49	5.65052	Yes	Yes	0	8	9
650	2x46	2x50	3.31982	Yes	Yes	1	9	9
651	E1x49	E2	4.3572	No	Yes	1	5	7
652	3x28	E1x50	2.81314	No	Yes	0	7	8
653	3x22	3x26	3.16856	No	No	0	4	7
654	3x40	5x50	2.78881	No	No	0	9	6
655	3x44	5x53	5.66682	No	No	0	7	5
656	3x46	7x53	4.18452	No	Yes	1	9	9
657	3x47	5x57	3.59332	No	No	0	9	5
658	3x50	5x58	7.02151	Yes	Yes	0	9	8
659	3x50	7x53	4.74258	Yes	Yes	1	9	9
660	3x51	3x52	2.39364	Yes	No	0	8	6
661	3x51	5x57	5.89367	Yes	No	0	8	5
662	3x51	5x60	4.12548	Yes	No	0	8	4
663	3x54	5x61	2.73795	No	No	0	8	7
664	I2x55	I2x56	2.56738	No	No	0	6	6
665	4x60	5x39	2.84958	No	No	0	8	5
666	E2	E2x52	3.81239	Yes	No	1	7	7
667	5x39	E2	4.76418	No	Yes	1	5	7
668	5x39	5x43	2.7381	No	No	0	5	7
669	5x40	6x55	2.61429	No	No	0	8	8
670	5x47	5x48	5.08482	Yes	No	0	8	9
671	5x47	6x48	3.03015	Yes	Yes	1	8	9
672	5x47	6x49	4.22776	Yes	Yes	0	8	7
673	5x49	5x50	3.04367	No	No	0	7	6
674	5x54	6x44	4.34633	No	No	0	8	9
675	5x58	6x37	6.55594	Yes	No	0	8	8
676	5x58	6x40	2.99795	Yes	No	0	8	8
677	5x58	6x41	3.02398	Yes	No	0	8	7
678	5x62	6x34	2.61301	No	No	0	9	8
679	5x62	6x37	3.14929	No	No	0	9	8
680	5x65	6x33	2.88596	No	No	0	7	8
681	5x66	6x30	2.88425	No	No	0	8	9
682	7x49	7x53	3.72927	Yes	Yes	1	9	9
683	G.S1.02	G.S1.04	2.72812	Yes	Yes	3	4	7
684	G.S1.02	G.S3.01	3.85981	Yes	Yes	3	4	4
685	G.H5.11	G.S1.02	2.95183	No	Yes	3	8	4
686	G.S4.04	G.s1h1.01	3.3191	Yes	No	0	9	9
687	G.S4.07	G.s1h1.05	4.79882	No	No	0	8	9
688	G.H1.01	G.S3.07	8.93132	No	Yes	3	9	9
689	G.H1.04	G.S5.07	3.75037	No	Yes	3	7	9
690	G.S2.06	G.S3.05	2.47087	Yes	Yes	0	8	6
691	G.H5.05	G.s2s3.01	3.63732	Yes	No	3	5	4
692	G.H2.08	G.H3.18	4.24883	No	Yes	0	8	9
693	G.S4.02	G.h3s5.03	2.72876	Yes	No	19	7	8
694	G.H5.07	G.S4.03	2.47301	No	Yes	3	8	7
695	G.s4h3.02	G.s5hg.01	3.58579	No	Yes	20	9	9
696	G.H3.09	G.S6.01	2.3803	Yes	Yes	9	9	5
697	G.H3.15	G.H3.17	3.25617	No	Yes	0	8	4
698	G.H4.03	G.HG.01	6.89399	Yes	No	0	3	5
699	G.H4.06	G.HG.04	2.42562	No	Yes	0	7	8
700	G.H4.02	G.H4.04	5.17998	No	No	22	5	4
701	G.h4s6.08	G.h4s6.11	5.98521	No	No	0	5	8
702	G.H5.08	G.H5.12	3.33328	Yes	No	0	8	7
703	5x65	G.H5.20	3.03705	No	No	0	7	8
704	b.1x4	g.h1x4	3.09669	Yes	No	0	8	5
705	b.lh12x2	g.h2x2	3.77541	No	No	0	8	9
706	b.h2x3	b.lh12x3	2.36564	No	No	0	1	4
707	b.h2x5	b.lhb1x3	2.70825	No	No	0	5	2
708	b.b12x3	b.b15x1	2.75246	No	Yes	5	8	9
709	b.b15x3	b.l13x7	2.66987	No	No	5	9	9
710	b.b19x4	b.l17x3	5.68121	Yes	Yes	6	8	9
711	b.l17x5	b.l19x1	3.02433	No	No	0	6	9
712	b.l25x5	b.l28x1	6.86968	No	Yes	0	7	9
713	g.ctx2	g.h2x15	3.31679	No	No	0	3	6
714	1x39	2x57	3.58471	Yes	Yes	0	5	8
715	1x43	2x57	3.34844	No	Yes	0	7	8
716	1x43	2x58	3.43227	No	No	0	7	9
717	2x50	3x39	2.44965	Yes	No	0	9	9
718	E1x50	E2	2.93626	Yes	Yes	1	8	7
719	3x37	4x56	3.7902	No	No	0	8	8
720	3x48	5x53	2.89665	No	No	0	7	5
721	3x48	5x57	2.90499	No	No	0	7	5
722	5x40	6x59	3.60933	No	No	0	8	7
723	5x44	5x48	2.65894	No	No	0	9	9
724	5x44	6x52	3.45684	No	Yes	0	9	8
725	5x47	5x51	3.84964	Yes	No	0	8	9
726	5x56	5x60	3.4594	No	No	0	6	4
727	G.HN.45	G.HN.49	3.82071	No	No	0	4	4
728	G.S1.04	G.S3.05	3.62522	Yes	Yes	0	7	6
729	G.H3.02	G.H4.11	2.38411	No	No	0	6	8
730	6x32	G.H5.26	4.65883	No	Yes	0	9	5
731	b.1x22	b.b21x2	2.87986	No	Yes	0	3	6
732	b.l5x4	b.l5x5	3.71395	No	Yes	0	8	9
733	b.b25x3	b.l21x2	4.82523	Yes	Yes	0	5	4
734	b.b24x2	b.b24x4	2.49094	Yes	Yes	7	5	6
735	1x39	7x39	2.65045	Yes	No	0	5	7
736	2x50	7x49	4.3852	Yes	Yes	1	9	9
737	2x53	3x32	3.41073	Yes	Yes	1	8	8
738	2x53	7x42	2.69706	Yes	Yes	1	8	8
739	3x56	I2x52	3.98426	No	No	0	7	6
740	E2	E2x51	7.78248	Yes	No	1	7	4
741	E2x51	E2x52	4.18608	No	No	1	4	7
742	g.h1x5	g.h1x9	5.61043	Yes	No	0	6	6
743	G.H2.03	G.H2.06	2.90786	No	Yes	2	9	9
744	G.H2.03	b.l13x6	3.18999	No	Yes	2	9	9
745	G.hgh4.01	G.s4h3.04	3.79557	Yes	No	0	4	8
746	G.H3.02	G.hgh4.01	2.64086	No	Yes	13	6	4
747	G.H3.02	G.hgh4.02	2.64422	No	Yes	13	6	8
748	b.1x2	b.1x5	2.61041	Yes	No	0	0	3
749	b.b24x7	b.b25x2	3.11706	Yes	No	8	9	2
750	b.l21x2	b.l21x3	2.58928	Yes	No	0	4	3
751	E2	E2	37.3707	Yes	Yes	1	7	7
752	6x30	6x31	3.05286	No	No	0	9	7
753	7x34	7x38	2.75671	No	Yes	1	6	7
754	1x35	2x64	4.47183	Yes	No	0	6	7
755	1x60	8x53	12.901	No	No	0	8	8
756	3x22	E2	6.23894	No	Yes	1	4	7
757	3x30	4x62	5.39394	No	No	0	8	5
758	3x50	G.H5.25	4.03411	Yes	No	0	9	6
759	4x56	5x46	2.77761	No	No	0	8	6
760	4x64	E2	10.2259	No	Yes	1	0	7
761	E2	Lig	18.9416	Yes	Yes	1	7	0
762	G.S4.07	G.s4h3.03	3.25167	No	No	0	8	0
763	3x33	4x61	3.68778	No	No	0	8	7
764	1x59	8x57	4.62817	No	No	0	7	8
765	7x34	Lig	5.94917	No	Yes	1	6	0
766	4x63	4x64	3.08944	No	No	0	0	0
767	G.H4.04	G.H4.05	2.46211	No	Yes	22	4	4
768	G.S6.02	I3	3.23083	Yes	Yes	23	8	0
769	G.H5.13	I3	2.758	Yes	Yes	23	7	0
770	2x60	Lig	2.74	No	Yes	1	8	0
771	5x35	E2	7.43117	No	Yes	1	0	7
772	Lig	NT	18.3923	Yes	Yes	1	0	5.33333
773	NT	NT	8.3775	Yes	Yes	1	5.33333	5.33333
774	I1x49	b.l25x4	2.39	No	No	0	7	5
775	3x29	4x65	6.989	No	Yes	0	7	0
776	4x61	4x65	2.70567	No	Yes	0	7	0
777	4x65	E2x52	4.30433	Yes	No	0	0	7
778	E3	Lig	8.00817	Yes	Yes	1	5	0
779	7x27	E3	2.54867	No	Yes	0	0	5
780	Lig	Lig	114.42	Yes	Yes	1	0	0
781	E2x51	Lig	3.0975	No	Yes	1	4	0
782	2x60	3x32	5.29383	No	Yes	1	8	8
783	G.HG.15	G.hgh4.06	2.75133	No	No	0	7	2
784	5x34	E2	3.086	No	Yes	0	0	7
785	2x38	I2	2.89667	No	No	0	7	0
786	3x49	I2	2.78	Yes	No	0	9	0
787	6x29	I3	2.79667	No	Yes	0	8	0
788	2x39	3x49	2.34554	No	Yes	0	9	9
789	b.l22x2	g.ctx3	2.33806	No	Yes	0	1	9
790	G.h4s6.09	G.h4s6.10	2.33763	No	No	0	4	3
791	G.h3s5.02	G.h4s6.10	2.3301	No	No	0	4	3
792	G.H3.01	G.s1h1.04	2.3216	Yes	No	0	8	8
793	b.1x7	g.h1x8	2.30489	No	No	0	8	7
794	1x53	2x47	2.30173	No	No	0	9	9
795	G.S2.07	G.S3.02	2.29715	No	No	0	3	3
796	7x51	7x55	2.28736	No	No	0	7	7
797	1x39	2x61	2.28337	Yes	No	0	5	8
798	G.H3.01	G.s4h3.03	2.28024	Yes	No	0	8	0
799	G.S1.05	G.h2s4.04	2.27757	Yes	No	0	9	9
800	I1x48	I1x51	2.27625	No	No	0	8	7
801	3x31	3x35	2.27025	No	No	0	7	7
802	1x55	1x59	2.2581	No	No	0	7	7
803	b.b15x1	b.l16x1	2.24987	Yes	No	0	9	4
804	b.b10x5	b.l6x2	2.23686	Yes	No	0	9	6
805	b.b18x4	b.b22x3	2.23095	No	No	0	3	6
806	G.H4.07	G.S6.05	2.22717	No	No	0	4	5
807	G.S5.07	G.s1h1.06	2.21898	Yes	No	0	9	9
808	b.b13x1	b.l12x3	2.21433	No	No	0	4	5
809	G.HG.13	G.HG.14	2.20946	No	No	0	6	5
810	G.H1.08	G.S2.06	2.20255	No	Yes	0	8	8
811	b.l21x8	b.l23x1	2.19491	No	Yes	0	4	6
812	b.1x15	g.h1x15	2.19475	No	No	0	7	8
813	G.H5.15	I2x50	2.17821	No	No	0	8	9
814	G.HG.14	G.HG.16	2.17611	No	No	0	5	4
815	2x54	2x57	2.17252	No	Yes	0	9	8
816	1x36	2x65	2.16969	No	No	0	6	7
817	g.h1x12	g.l1x1	2.16017	No	No	0	6	1
818	b.b1x3	g.ctx17	2.15539	No	No	0	7	7
819	2x39	2x40	2.14333	No	No	0	9	9
820	g.ctx7	g.ctx8	2.14167	No	No	0	4	8
821	G.H3.01	G.s1h1.03	2.12737	Yes	No	0	8	7
822	b.h2x4	g.h2x5	2.11754	No	No	0	3	6
823	b.b7x5	b.l7x1	2.11	No	No	0	9	9
824	1x27	7x32	2.10333	No	No	0	0	5
825	g.ctx17	g.ctx18	2.09533	No	No	0	7	0
826	b.b7x1	b.b9x1	2.0911	Yes	No	0	4	4
827	g.h2x14	g.h2x15	2.08988	No	No	0	4	6
828	G.H1.03	G.s6h5.04	2.08461	No	No	0	9	8
829	G.HG.07	G.HG.13	2.074	No	No	0	9	6
830	5x37	6x60	2.07397	No	No	0	6	5
831	1x54	2x47	2.07156	No	No	0	8	9
832	3x53	G.H5.23	2.0686	No	No	0	9	4
833	b.b6x1	b.l7x1	2.06667	No	No	0	9	9
834	6x43	7x52	2.04419	No	No	0	8	8
835	G.H3.03	G.s4h3.15	2.03873	No	No	0	4	9
836	b.b26x2	b.b27x4	2.03778	No	No	0	7	5
837	1x47	2x54	2.02839	No	No	0	7	9
838	b.1x4	g.h1x5	2.02278	Yes	Yes	0	8	6
839	b.l27x1	b.l27x4	2.02078	Yes	No	0	7	9
840	6x58	Lig	2.01906	No	Yes	1	5	0
841	b.l1x5	b.l3x2	2.00905	No	Yes	0	7	9
842	2x40	8x50	2.00536	No	Yes	0	9	8
843	4x40	4x43	2.00467	No	No	0	5	6
844	1x57	2x44	1.99714	No	No	0	8	7
845	b.b4x1	b.l5x1	1.995	No	Yes	0	8	8
846	G.H4.17	G.h4s6.01	1.99264	No	No	0	3	4
847	G.HG.02	G.HG.03	1.99205	No	No	0	9	6
848	G.S2.02	G.S3.07	1.98838	No	Yes	0	5	9
849	I2x52	I2x56	1.98196	No	No	0	6	6
850	5x51	5x55	1.97848	No	No	0	9	9
851	G.H3.01	G.H3.04	1.96972	Yes	No	0	8	9
852	G.s3h2.01	G.s3h2.02	1.96933	No	No	0	9	9
853	3x30	4x57	1.9627	No	No	0	8	8
854	6x61	E3	1.94583	No	Yes	0	3	5
855	b.b18x4	b.b22x5	1.92548	No	Yes	0	3	7
856	7x31	Lig	1.91172	No	Yes	0	4	0
857	G.HN.51	b.l1x4	1.9	No	No	0	4	6
858	b.b26x4	b.b2x3	1.89367	No	Yes	0	5	6
859	G.HN.43	b.b5x6	1.88029	No	No	0	8	6
860	b.b12x1	b.l13x5	1.87778	No	No	0	6	5
861	b.l14x1	b.l14x2	1.87	No	No	0	4	4
862	6x57	E3	1.86926	No	Yes	0	7	5
863	G.H5.11	G.H5.15	1.86918	No	No	0	8	8
864	b.l2x2	b.l6x2	1.86667	No	No	0	1	6
865	G.H1.05	G.S3.05	1.86013	No	Yes	0	7	6
866	G.hfs2.05	b.l7x4	1.85333	No	Yes	0	9	9
867	1x35	1x39	1.8464	Yes	Yes	0	6	5
868	4x38	4x41	1.84632	No	No	0	8	8
869	b.h2x4	g.h2x2	1.84032	No	No	0	3	9
870	b.1x11	b.1x7	1.83955	Yes	No	0	8	8
871	b.1x2	b.1x6	1.83572	Yes	No	0	0	3
872	4x41	4x45	1.83322	No	No	0	8	7
873	5x62	5x66	1.82852	No	No	0	9	8
874	5x37	6x59	1.82817	No	No	0	6	7
875	8x52	8x55	1.82697	No	No	0	6	6
876	7x24	NT	1.82	No	Yes	1	0	5.33333
877	G.H5.15	G.H5.19	1.81535	No	No	0	8	8
878	G.HN.37	b.b5x2	1.81509	No	Yes	0	2	7
879	5x44	6x56	1.81336	No	No	0	9	7
880	3x41	4x52	1.81061	No	No	0	7	7
881	g.ctx1	g.ctx2	1.80107	No	No	0	1	3
882	1x26	7x28	1.8	No	No	0	0	0
883	b.b12x2	b.l13x1	1.79553	No	No	0	7	2
884	b.l13x5	b.l15x2	1.7919	No	Yes	0	5	9
885	5x45	5x48	1.78549	No	No	0	7	9
886	b.b4x6	b.l1x2	1.78115	Yes	No	0	9	9
887	G.S4.01	G.S5.03	1.778	No	No	0	8	8
888	b.1x1	b.1x5	1.77584	No	No	0	0	3
889	b.1x11	b.1x14	1.7731	Yes	No	0	8	4
890	3x34	4x54	1.76917	No	No	0	7	7
891	1x54	2x48	1.75061	No	No	0	8	7
892	2x66	2x67	1.72722	No	No	0	7	6
893	b.l27x2	b.l2x2	1.7197	No	No	0	1	1
894	6x64	E3	1.70333	No	Yes	0	0	5
895	g.ctx14	g.ctx9	1.70059	No	No	0	9	6
896	5x51	5x52	1.69406	No	No	0	9	7
897	b.b9x2	b.b9x4	1.65263	No	No	0	5	9
898	1x46	2x54	1.65051	No	No	0	8	9
899	G.s6h5.02	G.s6h5.05	1.6486	No	No	0	7	9
900	1x60	I1x50	1.64582	No	No	0	8	9
901	3x37	5x461	1.6436	No	No	0	8	0
902	2x44	I1x51	1.62	No	No	0	7	7
903	4x59	4x60	1.61837	No	No	0	8	8
904	8x53	8x57	1.61333	No	No	0	8	8
905	1x32	2x65	1.60994	No	No	0	4	7
906	6x65	Lig	1.59667	No	Yes	0	0	0
907	1x45	7x47	1.58992	No	No	0	5	8
908	1x35	1x36	1.57	Yes	No	0	6	6
909	g.h1x11	g.h1x7	1.56759	No	No	0	9	2
910	4x64	4x68	1.56611	No	No	0	0	0
911	4x65	4x66	1.56167	Yes	No	0	0	0
912	3x27	3x31	1.54732	No	No	0	6	7
913	G.hgh4.02	G.hgh4.03	1.54345	Yes	No	0	8	6
914	5x60	5x63	1.54231	No	No	0	4	8
915	b.b24x2	b.l25x1	1.54052	Yes	No	0	5	3
916	8x48	G.H5.26	1.53898	No	Yes	0	6	5
917	g.h1x13	g.h1x9	1.53054	No	No	0	1	6
918	G.H3.05	G.s1h1.02	1.5295	No	No	0	9	7
919	2x49	4x50	1.52808	No	No	0	8	9
920	6x57	7x30	1.52617	No	No	0	7	7
921	b.b25x4	b.lhb1x6	1.52567	No	Yes	0	4	3
922	G.HN.44	G.HN.48	1.51929	No	No	0	6	4
923	7x55	8x50	1.51611	No	Yes	0	7	8
924	6x39	7x52	1.50763	No	No	0	7	8
925	G.HG.09	G.HG.12	1.50179	No	No	0	1	2
926	1x27	NT	1.49	No	Yes	1	0	5.33333
927	b.h2x5	g.h2x9	1.48324	No	No	0	5	4
928	3x21	3x24	1.48187	No	No	0	7	6
929	3x55	5x64	1.47421	No	No	0	7	6
930	b.lhb1x6	b.lhb1x7	1.46616	Yes	No	0	3	1
931	b.b21x5	b.h2x2	1.46483	Yes	No	0	4	1
932	b.b16x3	b.b19x2	1.45938	No	Yes	0	6	6
933	G.H1.03	G.s1h1.06	1.45456	No	No	0	9	9
934	1x51	2x51	1.42302	No	No	0	6	8
935	2x38	4x39	1.4148	No	No	0	7	6
936	2x66	E1x51	1.40635	No	No	0	7	5
937	6x50	7x40	1.39394	No	No	0	9	8
938	6x24	6x25	1.38943	No	No	0	6	4
939	b.b16x1	b.l17x3	1.38932	No	Yes	0	4	9
940	G.S3.01	I2x51	1.38875	Yes	No	0	4	7
941	G.hns1.02	I2	1.38333	No	No	0	4	0
942	b.1x10	b.1x14	1.37752	No	No	0	1	4
943	5x41	6x56	1.3696	No	No	0	7	7
944	b.lhb1x1	b.lhb1x2	1.36003	No	No	0	1	1
945	6x43	7x48	1.35779	No	No	0	8	7
946	b.b1x1	b.lhb1x10	1.35052	No	No	0	5	4
947	b.1x12	b.1x9	1.34786	No	No	0	6	4
948	1x49	7x50	1.33383	No	No	0	9	9
949	1x41	1x45	1.32676	No	No	0	5	5
950	5x69	6x26	1.31822	No	No	0	8	5
951	G.HN.49	G.HN.50	1.31651	No	Yes	0	4	5
952	g.h1x10	g.h1x6	1.31117	No	No	0	9	4
953	7x55	7x56	1.3032	No	No	0	7	8
954	G.s2s3.02	I2x55	1.29375	No	No	0	4	6
955	G.H1.09	G.S2.05	1.28089	No	No	0	7	3
956	6x49	6x53	1.2801	Yes	No	0	7	7
957	g.ctx6	g.ctx7	1.27621	Yes	No	0	6	4
958	b.1x2	b.ntx3	1.27444	Yes	No	0	0	0
959	1x38	7x39	1.27017	No	No	0	5	7
960	6x32	6x35	1.26094	No	No	0	9	7
961	b.b16x6	b.l13x2	1.18984	Yes	No	0	8	6
962	1x42	7x47	1.1893	No	No	0	7	8
963	b.1x12	b.1x15	1.1861	No	No	0	6	7
964	1x25	1x28	1.16667	No	No	0	0	0
965	8x47	G.H5.24	1.15711	No	No	0	9	8
966	2x62	E1x52	1.1535	No	Yes	0	7	7
967	5x64	5x67	1.1459	No	No	0	6	8
968	b.1x3	b.1x4	1.14422	No	Yes	0	1	8
969	7x30	7x33	1.14329	No	No	0	7	7
970	b.l22x3	g.h2x16	1.14	No	No	0	9	4
971	G.H1.11	G.S2.05	1.13417	No	No	0	0	3
972	G.H5.01	G.s6h5.01	1.13389	No	Yes	0	8	9
973	6x34	6x38	1.12028	No	No	0	8	7
974	G.HG.12	G.HG.13	1.11836	No	No	0	2	6
975	7x40	7x43	1.09876	No	No	0	8	7
976	b.1x4	b.1x8	1.09833	Yes	No	0	8	5
977	5x42	5x46	1.09267	No	No	0	7	6
978	2x51	2x55	1.08733	No	No	0	8	6
979	G.H1.02	G.H1.03	1.08063	No	No	0	9	9
980	1x29	1x33	1.04939	No	No	0	0	5
981	G.HN.11	G.HN.33	1.04256	No	No	0	3	4
982	b.b28x6	b.l25x2	1.04003	Yes	No	0	9	5
983	6x23	6x26	1.0399	No	No	0	0	5
984	6x27	6x31	1.0399	No	No	0	6	7
985	E1	E1x49	1.03544	No	No	0	0	5
986	1x29	1x30	1.0295	No	No	0	0	4
987	G.H3.01	G.s4h3.06	1.02349	Yes	No	0	8	0
988	8x53	8x56	1.01672	No	No	0	8	7
989	b.b21x3	b.l17x2	1.01594	Yes	No	0	6	6
990	b.b20x1	b.l21x5	1.0061	No	No	0	5	4
991	G.S3.07	G.s3h2.01	0.996	Yes	No	0	9	9
992	G.H2.04	G.H3.11	0.990381	No	No	0	9	7
993	b.b25x5	b.b25x6	0.979873	No	Yes	0	4	3
994	b.b22x5	b.l24x1	0.975317	Yes	No	0	7	5
995	b.1x2	b.1x3	0.966	Yes	No	0	0	1
996	b.l8x4	b.l8x5	0.953325	No	Yes	0	3	3
997	1x28	1x31	0.951111	No	No	0	0	5
998	1x26	1x27	0.95	No	No	0	0	0
999	5x69	G.H5.13	0.938222	No	Yes	0	8	7
1000	1x48	1x49	0.934762	No	No	0	5	9
1001	G.s5hg.01	G.s6h5.03	0.934389	Yes	No	0	9	9
1002	G.H5.17	I3	0.916833	No	Yes	0	5	0
1003	1x29	NT	0.875667	No	Yes	1	0	5.33333
1004	4x58	4x59	0.875238	No	No	0	6	8
1005	5x36	5x38	0.863492	No	No	0	5	5
1006	1x34	7x35	0.863333	No	No	0	3	7
1007	G.hfs2.06	b.l7x4	0.852706	No	Yes	0	8	9
1008	G.HN.46	G.HN.50	0.846421	No	Yes	0	4	5
1009	G.H2.01	G.s3h2.02	0.844048	No	No	0	9	9
1010	g.h2x13	g.h2x9	0.827	No	No	0	1	4
1011	b.l24x3	b.lhb1x1	0.814444	Yes	No	0	5	1
1012	I2x54	I2x55	0.811667	No	No	0	7	6
1013	6x24	6x27	0.81	No	No	0	6	6
1014	g.ctx11	g.ctx18	0.805333	No	No	0	4	0
1015	b.b16x2	b.l17x1	0.80127	No	No	0	5	2
1016	b.l8x5	b.l8x6	0.765333	Yes	No	0	3	4
1017	5x32	5x35	0.756667	No	No	0	0	0
1018	7x36	7x40	0.753778	No	No	0	6	8
1019	G.HN.10	G.HN.37	0.746111	No	No	0	3	2
1020	G.HN.48	G.HN.52	0.73469	No	No	0	4	4
1021	G.HG.06	G.HG.09	0.730714	No	No	0	5	1
1022	5x59	5x63	0.684087	No	No	0	9	8
1023	G.HN.30	G.HN.31	0.684	Yes	No	0	8	3
1024	6x28	6x29	0.669873	No	No	0	5	8
1025	4x48	4x52	0.643159	No	No	0	5	7
1026	1x44	1x45	0.635333	No	No	0	6	5
1027	5x32	5x33	0.628833	No	No	0	0	0
1028	8x55	8x61	0.622	No	No	0	6	0
1029	4x40	4x44	0.614167	No	No	0	5	3
1030	G.H1.10	G.S2.04	0.608	No	No	0	0	7
1031	b.1x16	b.1x20	0.577722	No	No	0	4	2
1032	1x40	1x43	0.576063	No	No	0	6	7
1033	6x42	6x46	0.573095	No	No	0	7	5
1034	3x23	3x27	0.562944	No	No	0	5	6
1035	6x63	Lig	0.56	No	Yes	0	0	0
1036	g.l1x3	g.l1x5	0.553333	No	No	0	1	4
1037	7x23	7x26	0.543333	No	No	0	0	0
1038	G.H3.01	G.s4h3.08	0.539587	Yes	No	0	8	0
1039	1x34	1x37	0.526262	No	No	0	3	5
1040	6x41	6x42	0.526222	No	No	0	7	7
1041	G.HN.36	b.b5x2	0.52619	No	Yes	0	4	7
1042	4x55	4x56	0.519111	No	No	0	6	8
1043	8x50	I1	0.518333	Yes	No	0	8	0
1044	g.h1x2	g.h1x5	0.517944	No	Yes	0	2	6
1045	7x26	7x30	0.516667	No	No	0	0	7
1046	1x58	2x44	0.50781	No	No	0	6	7
1047	G.HN.11	G.HN.34	0.504683	No	No	0	3	3
1048	G.hns1.03	I2x52	0.500556	No	No	0	4	6
1049	b.1x1	g.ntx1	0.5	No	No	0	0	0
1050	G.H1.06	G.S2.06	0.496	No	Yes	0	9	8
1051	6x58	6x62	0.49	No	No	0	5	0
1052	1x60	CT	0.4855	No	No	0	8	0
1053	g.h1x1	g.ntx3	0.482722	No	No	0	2	0
1054	G.HN.38	G.HN.42	0.475302	No	No	0	3	4
1055	5x66	5x70	0.466667	No	No	0	8	5
1056	8x56	8x60	0.46	No	No	0	7	0
1057	G.HN.51	G.hns1.01	0.44881	No	No	0	4	3
1058	b.1x3	b.ntx1	0.423333	No	No	0	1	0
1059	G.H3.05	G.H3.07	0.408	No	No	0	9	5
1060	4x43	4x47	0.404667	No	No	0	6	5
1061	g.h1x3	g.h1x4	0.379167	No	No	0	3	5
1062	8x54	8x58	0.373111	No	No	0	8	8
1063	7x29	E3	0.366667	No	Yes	0	0	5
1064	4x51	4x55	0.34481	No	No	0	5	6
1065	G.HN.29	G.HN.34	0.324	No	No	0	0	3
1066	G.H5.21	G.H5.22	0.277381	Yes	No	0	4	4
1067	G.HN.10	G.HN.34	0.273143	No	No	0	3	3
1068	G.HN.30	G.HN.32	0.261714	Yes	No	0	8	5
1069	7x60	CT	0.236667	No	No	0	0	0
1070	7x24	7x25	0.234333	No	No	0	0	0
1071	G.HN.50	G.HN.53	0.220667	Yes	No	0	5	2
1072	7x58	7x61	0.213333	No	No	0	0	0
1073	g.h2x3	g.h2x6	0.205556	No	No	0	5	2
1074	6x32	7x58	0.180833	No	No	0	9	0
1075	G.HN.28	G.HN.30	0.177778	No	Yes	0	0	8
1076	8x58	8x59	0.176349	No	No	0	8	6
1077	b.1x21	b.b21x2	0.169444	No	Yes	0	3	6
1078	G.HN.38	G.HN.41	0.1425	No	No	0	3	4
1079	G.s4h3.08	G.s4h3.14	0.140317	No	No	0	0	0
1080	4x63	4x67	0.139444	No	No	0	0	0
1081	b.l21x6	b.l21x7	0.109333	No	No	0	3	5
1082	G.HG.17	G.s4h3.07	0.102667	No	No	0	3	0
1083	5x70	5x71	0.1	No	No	0	5	7
1084	G.s4h3.13	G.s4h3.14	0.0996825	No	No	0	0	0
1085	4x69	E2	0.0966667	No	Yes	0	0	7
1086	g.h2x10	g.h2x13	0.0838889	No	No	0	3	1
1087	b.1x1	g.ntx2	0.0833333	No	No	0	0	0
1088	b.lh12x5	g.h2x5	0.0750794	No	No	0	0	6
1089	b.1x4	b.ntx2	0.0736111	Yes	No	0	8	0
1090	6x22	G.h4s6.03	0.067619	No	No	0	0	4
1091	G.HN.35	G.HN.38	0.0659127	No	No	0	3	3
1092	g.h1x1	g.ntx4	0.0516667	No	No	0	2	0
1093	G.H4.13	G.H4.16	0.0479365	No	Yes	0	2	3
1094	7x57	G.H5.24	0.0351667	No	No	0	0	8
1095	7x59	7x60	0.0251667	No	No	0	0	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	G.HN.30	1.80513	4	0	8
2	G.HN.50	1.84727	4	0	5
3	G.S1.02	4.31906	5	3	4
4	G.S1.04	3.04339	4	3	7
5	G.S1.05	4.9798	4	0	9
6	G.S1.06	3.78979	4	3	8
7	G.S2.06	4.30448	4	0	8
8	G.S2.08	6.33142	4	3	5
9	G.S3.01	3.49115	4	3	4
10	G.S3.03	6.24991	5	3	7
11	G.S3.05	2.90111	4	0	6
12	G.S3.06	7.88417	5	2	6
13	G.S3.07	3.76492	4	3	9
14	G.H2.06	4.31211	7	2	9
15	G.H2.07	6.18472	4	2	9
16	G.H2.09	5.28398	4	12	8
17	G.h2s4.01	5.63708	4	2	9
18	G.S4.02	3.36064	4	19	7
19	G.S4.03	2.86524	4	3	7
20	G.S4.04	5.53949	4	0	9
21	G.S4.06	3.78706	4	0	7
22	G.H3.01	2.04287	7	0	8
23	G.H3.09	5.73948	6	9	9
24	G.H3.17	4.80049	4	0	4
25	G.H3.18	5.12143	4	19	9
26	G.S5.04	3.44883	5	9	9
27	G.S5.05	3.39343	8	3	9
28	G.S5.06	3.7288	4	0	8
29	G.S5.07	3.38265	4	3	9
30	G.s5hg.01	3.42011	4	20	9
31	G.HG.04	5.3961	4	0	8
32	G.hgh4.01	3.64437	4	13	4
33	G.hgh4.02	3.9028	5	13	8
34	G.hgh4.05	4.602	4	0	6
35	G.H4.03	4.65813	4	0	3
36	G.H4.05	4.3	4	22	4
37	G.H4.15	5.28178	5	9	8
38	G.H4.16	3.04624	4	9	3
39	G.S6.01	3.68907	4	9	5
40	G.S6.02	6.18273	5	23	8
41	G.s6h5.01	3.92067	4	3	9
42	G.H5.05	3.95533	4	3	5
43	G.H5.08	4.91813	4	3	8
44	G.H5.13	3.69343	4	23	7
45	G.H5.21	2.46054	4	0	4
46	G.H5.26	4.3915	4	0	5
47	b.1x4	1.48713	5	0	8
48	b.1x11	3.05992	4	0	8
49	b.lhb1x6	2.88174	6	8	3
50	b.l1x3	7.49733	6	4	9
51	b.b2x1	7.3181	5	12	8
52	b.b2x3	3.1858	4	4	6
53	b.b2x5	6.75727	5	4	7
54	b.l3x2	5.03675	5	4	9
55	b.b4x3	3.73831	4	14	7
56	b.b4x5	3.75887	4	17	7
57	b.b4x6	7.56752	7	4	9
58	b.b4x7	6.97212	4	18	8
59	b.l4x2	9.97715	4	4	4
60	b.b5x2	4.17792	5	18	7
61	b.b5x3	5.7497	5	4	9
62	b.b5x5	4.72319	4	17	5
63	b.b5x7	4.30863	4	0	7
64	b.l5x1	3.52509	5	14	8
65	b.l5x5	6.23275	6	2	9
66	b.b6x5	3.68301	6	0	6
67	b.l6x5	5.07327	4	15	4
68	b.b7x1	4.7317	5	15	4
69	b.b7x4	3.19128	4	14	8
70	b.l7x4	2.99258	5	0	9
71	b.b8x4	4.32741	5	14	6
72	b.l8x5	2.93015	5	16	3
73	b.l9x3	6.15642	5	2	9
74	b.l9x6	4.28435	10	2	8
75	b.b10x5	3.96675	6	0	9
76	b.l11x2	6.81608	4	2	9
77	b.b12x6	6.64119	7	2	8
78	b.b13x7	7.07369	5	5	7
79	b.l13x3	6.43447	6	5	9
80	b.l13x6	4.87348	5	2	9
81	b.b14x3	3.95072	4	5	5
82	b.b15x1	5.51217	6	5	9
83	b.b15x2	5.96047	4	6	6
84	b.l15x1	5.00946	4	2	7
85	b.l15x2	4.54943	5	5	9
86	b.b16x4	9.21253	4	5	6
87	b.b16x5	3.83428	5	0	5
88	b.b16x6	6.91492	7	5	8
89	b.b17x5	6.28866	4	6	7
90	b.b17x7	7.29821	4	6	8
91	b.l17x3	6.74955	6	6	9
92	b.b18x3	4.50563	4	6	8
93	b.l18x1	5.34046	7	11	6
94	b.l18x2	5.47569	4	11	7
95	b.b19x2	6.26738	5	6	6
96	b.b19x4	5.08352	4	6	8
97	b.l19x2	5.44945	5	6	9
98	b.b20x4	9.22699	5	6	8
99	b.b20x6	6.90695	5	6	6
100	b.b21x1	8.38261	4	6	7
101	b.b21x2	2.49779	5	0	6
102	b.b21x3	6.66147	4	6	6
103	b.b21x5	4.70054	4	7	4
104	b.b21x7	5.50334	6	7	5
105	b.l21x2	4.25045	4	0	4
106	b.b22x5	4.31912	6	11	7
107	b.l22x5	5.66103	6	8	9
108	b.b23x6	6.48729	6	7	7
109	b.l23x1	6.66353	4	0	6
110	b.b24x2	3.38642	4	7	5
111	b.b24x4	6.19528	5	7	6
112	b.b24x6	6.13991	4	7	8
113	b.b24x7	7.30261	4	8	9
114	b.l24x3	4.26646	5	8	5
115	b.b25x3	6.23901	4	7	5
116	b.b25x6	2.88232	4	7	3
117	b.l25x3	8.51423	5	10	9
118	b.l27x1	6.54625	4	4	7
119	b.l28x1	9.76303	6	12	9
120	b.l28x2	6.94305	4	10	9
121	b.b28x4	7.23731	4	10	6
122	b.b28x6	7.10056	5	10	9
123	g.h1x5	3.02029	4	0	6
124	g.l1x4	4.58666	4	0	8
125	g.h2x11	8.27792	4	11	6
126	g.ctx3	6.40105	5	0	9
127	g.ctx6	3.45815	5	8	6
128	g.ctx15	6.02129	4	4	9
129	g.ctx16	4.4362	7	4	8
130	1x35	2.58563	4	0	6
131	1x39	2.59123	4	0	5
132	2x42	3.88021	6	0	8
133	2x46	3.44199	4	1	9
134	2x50	4.71756	6	1	9
135	2x53	3.54898	4	1	8
136	2x57	3.42368	4	0	8
137	E1x50	5.26763	6	1	8
138	E1x52	4.03047	4	0	7
139	3x32	4.68214	5	1	8
140	3x49	3.66303	4	0	9
141	3x50	4.78033	5	1	9
142	3x51	5.44244	4	0	8
143	E2	10.859	14	1	7
144	5x47	5.83682	5	1	8
145	5x58	4.84901	6	0	8
146	6x48	4.76769	7	1	9
147	6x49	2.84922	4	0	7
148	6x51	4.22309	4	1	8
149	6x52	6.14525	4	1	8
150	E3	2.74032	6	1	5
151	7x38	3.79137	4	1	7
152	7x42	3.73943	6	1	8
153	7x45	6.81552	4	1	9
154	7x49	4.71792	5	1	9
155	7x53	3.92277	7	1	9
156	8x50	3.22635	9	0	8
157	Lig	16.9484	19	1	0
158	b.1x2	1.67164	4	0	0
159	4x65	3.89017	4	0	0
160	I3	2.42558	4	23	0
161	NT	6.5555	6	1	5.33333

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	b.b3x1	b.b4x7	15.1791	2.60844	No	Yes	0	5	8
2	b.b3x1	b.b6x5	29.4995	3.37629	No	Yes	0	5	6
3	b.b3x3	b.b6x5	13.7816	6.3875	No	Yes	0	8	6
4	b.b26x2	b.b2x3	45.5606	4.536	No	Yes	0	7	6
5	b.b26x1	b.b26x2	45.7698	3.57241	No	No	0	9	7
6	b.b26x1	b.l28x1	45.8744	5.44397	No	Yes	0	9	9
7	G.H2.09	b.l28x1	45.6729	3.95789	Yes	Yes	12	8	9
8	G.H2.09	G.H3.17	45.9414	4.59794	Yes	Yes	0	8	4
9	G.H3.15	G.H3.17	46.3111	3.25617	No	Yes	0	8	4
10	G.H3.15	G.H3.18	46.3843	3.70874	No	Yes	0	8	9
11	G.H3.18	G.S4.02	46.5289	5.28161	Yes	Yes	19	9	7
12	G.S4.02	G.S5.02	48.8674	2.66886	Yes	No	0	7	6
13	G.H3.09	G.S5.02	48.8813	4.97794	Yes	No	0	9	6
14	G.H3.09	G.H3.13	95.7719	3.98409	Yes	No	0	9	5
15	G.H3.13	G.h4s6.11	95.9085	4.284	No	No	0	5	8
16	G.h4s6.08	G.h4s6.11	100	5.98521	No	No	0	5	8
17	G.h4s6.08	G.h4s6.09	99.9882	4.02619	No	No	0	5	4
18	G.h4s6.09	G.h4s6.10	99.9763	2.33763	No	No	0	4	3
19	G.H5.21	G.h4s6.10	99.9394	3.5933	Yes	No	0	4	3
20	G.H5.21	G.H5.26	99.9009	3.45041	Yes	Yes	0	4	5
21	6x29	G.H5.26	99.7206	7.91779	No	Yes	0	8	5
22	6x29	I3	99.6897	2.79667	No	Yes	0	8	0
23	G.S6.02	I3	99.148	3.23083	Yes	Yes	23	8	0
24	G.H5.10	G.S6.02	99.4607	3.86975	No	Yes	0	7	8
25	G.H5.10	G.S5.03	99.4434	3.28416	No	No	0	7	8
26	G.S5.03	G.S5.05	99.4082	3.24394	No	Yes	0	8	9
27	G.S4.03	G.S5.05	98.9197	2.63727	Yes	Yes	3	7	9
28	G.S1.04	G.S4.03	98.0863	3.25329	Yes	Yes	3	7	7
29	G.S1.02	G.S1.04	49.0081	2.72812	Yes	Yes	3	4	7
30	G.S1.04	G.S3.03	49.2126	2.56692	Yes	Yes	3	7	7
31	G.H5.11	G.S3.03	48.4883	3.67086	No	Yes	3	8	7
32	G.H5.11	G.S1.02	47.9871	2.95183	No	Yes	3	8	4
33	G.H2.07	b.l9x6	47.7765	3.5906	Yes	Yes	2	9	8
34	G.H2.06	b.l9x6	47.0473	3.12706	Yes	Yes	2	9	8
35	G.H2.04	G.H2.07	48.3636	5.06413	No	Yes	0	9	9
36	G.H2.04	G.H3.08	48.203	4.08028	No	No	0	9	9
37	G.H2.06	b.l17x6	23.3013	7.7046	Yes	No	2	9	9
38	G.H3.09	G.S4.04	45.6993	12.1562	Yes	Yes	0	9	9
39	G.H5.11	G.H5.15	96.2954	1.86918	No	No	0	8	8
40	3x53	G.H5.19	95.5734	3.4205	No	No	0	9	8
41	G.H5.15	G.H5.19	95.7542	1.81535	No	No	0	8	8
42	3x50	G.H5.23	95.2114	4.77753	Yes	No	0	9	4
43	3x53	G.H5.23	95.3925	2.0686	No	No	0	9	4
44	b.l25x6	b.l28x1	15.6801	16.4572	No	Yes	0	8	9
45	b.l23x1	b.l25x6	15.549	15.4212	Yes	No	0	6	8
46	b.l21x7	b.l23x1	13.4256	5.71171	No	Yes	0	5	6
47	b.l21x7	b.l23x2	13.1548	5.91502	No	No	0	5	8
48	b.b23x6	b.l23x2	11.979	3.75467	Yes	No	0	7	8
49	b.b23x6	b.b24x6	10.246	6.96063	Yes	Yes	7	7	8
50	b.b21x7	b.b24x6	10.1122	7.98349	Yes	Yes	7	5	8
51	b.1x15	b.1x19	27.1137	3.79582	No	No	0	7	6
52	b.1x12	b.1x15	25.6471	1.1861	No	No	0	6	7
53	b.1x12	g.h1x11	21.2429	3.3314	No	No	0	6	9
54	b.1x11	g.h1x11	19.7734	4.72156	Yes	No	0	8	9
55	b.1x11	g.h1x12	16.0965	3.90548	Yes	No	0	8	6
56	b.b4x7	b.l2x5	15.0717	13.9365	Yes	No	0	8	5
57	b.l2x5	b.l4x2	29.9383	23.5592	No	Yes	0	5	4
58	b.l4x1	b.l4x2	28.762	2.52278	No	Yes	4	5	4
59	b.b2x5	b.l4x1	31.9924	4.94311	Yes	No	4	7	5
60	b.b2x4	b.b6x5	14.3839	2.55977	No	Yes	0	6	6
61	b.b10x4	b.b2x4	14.0884	12.2743	No	No	0	6	6
62	b.l2x3	b.l2x5	14.7542	4.15694	No	No	0	8	5
63	b.b3x1	b.l2x3	14.6168	3.62594	No	No	0	5	8
64	b.b3x3	b.b4x3	12.2954	3.15502	No	Yes	0	8	7
65	b.l11x1	b.l9x6	12.2389	5.62848	No	Yes	2	9	8
66	b.b11x6	b.l11x1	13.3259	3.33266	No	No	2	9	9
67	b.b11x6	b.l9x3	12.3062	14.9023	No	Yes	2	9	9
68	b.b12x6	b.l9x3	11.1045	3.4917	Yes	Yes	2	8	9
69	b.b10x2	b.b10x4	11.3992	3.21319	No	No	0	6	6
70	b.b10x2	b.b14x3	11.1024	4.03429	No	Yes	0	6	5
71	b.l17x6	b.l19x1	24.5063	4.20783	No	No	0	9	9
72	b.l17x5	b.l19x1	47.4139	3.02433	No	No	0	6	9
73	b.l17x5	b.l19x2	47.1477	4.00558	No	Yes	0	6	9
74	b.l17x3	b.l19x2	32.5129	3.705	Yes	Yes	6	9	9
75	b.b19x4	b.l17x3	18.145	5.68121	Yes	Yes	6	8	9
76	G.H2.06	b.b18x1	23.3016	2.5985	Yes	No	0	9	9
77	b.b18x1	b.l19x1	23.1797	7.6894	No	No	0	9	9
78	b.1x19	b.b21x1	29.4691	10.7629	No	Yes	0	6	7
79	b.b20x2	b.l19x2	13.8082	7.53738	No	Yes	0	6	9
80	b.b20x2	b.b20x4	13.2354	5.37426	No	Yes	0	6	8
81	b.b20x4	b.b20x6	24.1241	3.352	Yes	Yes	6	8	6
82	b.b20x4	b.l17x3	13.2425	11.8413	Yes	Yes	6	8	9
83	b.b19x4	b.b20x6	12.0868	6.3001	Yes	Yes	6	8	6
84	b.b17x7	b.b21x1	31.5698	3.43837	Yes	Yes	6	8	7
85	b.b17x7	b.b20x6	33.6237	8.53798	Yes	Yes	6	8	6
86	g.h1x12	g.h1x9	14.6244	3.39643	No	No	0	6	6
87	g.h1x5	g.h1x9	13.1517	5.61043	Yes	No	0	6	6
88	2x50	7x49	11.4571	4.3852	Yes	Yes	1	9	9
89	7x49	7x53	41.4849	3.72927	Yes	Yes	1	9	9
90	3x50	7x53	45.1164	4.74258	Yes	Yes	1	9	9
91	2x42	3x49	11.0076	5.65052	Yes	Yes	0	8	9
92	2x42	3x46	15.2319	4.20955	Yes	No	0	8	9
93	3x46	3x50	14.5585	3.32591	No	Yes	1	9	9
94	E2	Lig	18.3034	18.9416	Yes	Yes	1	7	0
95	3x36	Lig	39.0335	3.72214	No	Yes	1	7	0
96	3x36	6x48	39.4521	2.94307	No	Yes	1	7	9
97	6x44	6x48	26.2901	6.5172	No	Yes	1	9	9
98	5x54	6x44	26.5152	4.34633	No	No	0	8	9
99	5x54	5x58	26.7282	3.07742	No	Yes	0	8	8
100	3x50	5x58	34.8165	7.02151	Yes	Yes	0	9	8
101	6x48	7x45	26.6194	8.65636	Yes	Yes	1	9	9
102	7x45	7x49	27.0653	6.77086	Yes	Yes	1	9	9
103	b.b2x3	b.b2x5	38.9222	3.82666	Yes	Yes	4	6	7
104	G.H3.08	G.S4.04	48.1379	4.02735	No	Yes	0	9	9

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
2x56	3x32	4.21483	1	No	Yes	8	8	2	1
2x56	7x42	2.53293	1	No	Yes	8	8	2	1
2x57	7x42	4.58904	0	Yes	Yes	8	8	2	1
3x32	7x42	5.36489	1	Yes	Yes	8	8	1	1
3x32	Lig	5.1264	1	Yes	Yes	8	0	1	0
3x33	4x57	3.86988	1	No	No	8	8	1	2
3x33	Lig	3.94025	1	No	Yes	8	0	1	0
3x36	6x48	2.94307	1	No	Yes	7	9	1	2
3x36	Lig	3.72214	1	No	Yes	7	0	1	0
5x36	E2	7.61191	1	No	Yes	5	7	2	1
6x48	6x52	3.87736	1	Yes	Yes	9	8	2	2
6x51	6x52	4.25506	1	Yes	Yes	8	8	1	2
6x51	6x55	3.485	1	Yes	No	8	8	1	1
6x51	7x38	3.25679	1	Yes	Yes	8	7	1	1
6x51	Lig	5.89549	1	Yes	Yes	8	0	1	0
6x54	7x34	3.29863	0	No	No	7	6	2	1
6x55	Lig	4.00245	1	No	Yes	8	0	1	0
7x38	7x42	4.56389	1	Yes	Yes	7	8	1	1
7x38	Lig	4.58808	1	Yes	Yes	7	0	1	0
7x42	Lig	2.68876	1	Yes	Yes	8	0	1	0
E1x49	E2	4.3572	1	No	Yes	5	7	2	1
E2	E2x52	3.81239	1	Yes	No	7	7	1	2
5x39	E2	4.76418	1	No	Yes	5	7	2	1
5x40	6x55	2.61429	0	No	No	8	8	2	1
E1x50	E2	2.93626	1	Yes	Yes	8	7	2	1
2x53	3x32	3.41073	1	Yes	Yes	8	8	2	1
2x53	7x42	2.69706	1	Yes	Yes	8	8	2	1
E2	E2x51	7.78248	1	Yes	No	7	4	1	1
E2x51	E2x52	4.18608	1	No	No	4	7	1	2
E2	E2	37.3707	1	Yes	Yes	7	7	1	1
7x34	7x38	2.75671	1	No	Yes	6	7	1	1
3x22	E2	6.23894	1	No	Yes	4	7	2	1
4x64	E2	10.2259	1	No	Yes	0	7	2	1
E2	Lig	18.9416	1	Yes	Yes	7	0	1	0
3x33	4x61	3.68778	1	No	No	8	7	1	2
7x34	Lig	5.94917	1	No	Yes	6	0	1	0
2x60	Lig	2.74	1	No	Yes	8	0	1	0
5x35	E2	7.43117	1	No	Yes	0	7	2	1
Lig	NT	18.3923	1	Yes	Yes	0	5.33333	0	1
NT	NT	8.3775	1	Yes	Yes	5.33333	5.33333	1	1
E3	Lig	8.00817	1	Yes	Yes	5	0	1	0
7x27	E3	2.54867	0	No	Yes	0	5	2	1
E2x51	Lig	3.0975	1	No	Yes	4	0	1	0
2x60	3x32	5.29383	1	No	Yes	8	8	1	1
5x34	E2	3.086	0	No	Yes	0	7	2	1
6x58	Lig	2.01906	1	No	Yes	5	0	1	0
6x61	E3	1.94583	0	No	Yes	3	5	2	1
7x31	Lig	1.91172	0	No	Yes	4	0	1	0
6x57	E3	1.86926	0	No	Yes	7	5	2	1
7x24	NT	1.82	1	No	Yes	0	5.33333	2	1
6x64	E3	1.70333	0	No	Yes	0	5	2	1
6x65	Lig	1.59667	0	No	Yes	0	0	1	0
1x27	NT	1.49	1	No	Yes	0	5.33333	2	1
1x29	NT	0.875667	1	No	Yes	0	5.33333	2	1
6x63	Lig	0.56	0	No	Yes	0	0	1	0
6x58	6x62	0.49	1	No	No	5	0	1	2
7x29	E3	0.366667	0	No	Yes	0	5	2	1
4x69	E2	0.0966667	0	No	Yes	0	7	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
61.90	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2
61.90	Consensus	apelin_on	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
60.00	Consensus	gi_class-a	Orthosteric Ligand	gi_amine gi_lipid gi_melatonin gi_peptide gi_protein gi_nucleotide gi_hcar
58.33	Consensus	gq_class-a	Orthosteric Ligand	gq_amine gq_peptide
57.69	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_angiotensin gq_bombesin gq_bradykinin
57.14	Consensus	gi_apelin	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
55.56	Consensus	gi_peptide	Orthosteric Ligand	gi_opioid gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_neuromedin gi_neurotensin gi_relaxin gi_neuropeptide gi_somatostatin gi_apelin gi_compl-peptide gi_cck
55.00	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
54.55	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/&β;1/&γ;2
54.55	Consensus	sst2_on	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
52.63	Single	5C1M	BU72	5C1M-μ-BU72
52.38	Single	7EZC	UKA	7EZC-A_2A-UKA
52.17	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
52.17	Single	6DO1	Angiotensin-Like peptide S1I8	6DO1-AT₁-Angiotensin-Like peptide S1I8
52.17	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/&β;1/&γ;2
51.85	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_motilin gs_neuromedin gs_orexin gs_sst gs_tachykinin gs_trh gs_vasopressin-ot gs_bombesin gs_bradykinin gs_compl-peptide gs_endothelin gs_galanin gs_ghrelin gs_melanocortin
51.85	Consensus	peptide_on	Orthosteric Ligand	opioid_on angiotensin_on bombesin_on cck_on endothelin_on ghrelin_on npy_on nts_on orexin_on vasopressin-ot_on tachykinin_on sst_on relaxin_on trh_on nmur_on motilin_on melanocortin_on galanin_on fpr-alx_on compl-peptide_on bradykinin_on apelin_on
50.00	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
50.00	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
50.00	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
50.00	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
50.00	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2
50.00	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/&β;1/&γ;2
50.00	Single	8E0G	BU72	8E0G-μ-BU72
50.00	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
50.00	Consensus	arrestin2	Orthosteric Ligand	6TKO-β₁-Arformoterol-Arrestin2 6PWC-NTS₁-Neurotensin-Arrestin2 7R0C-V₂-Acyclovir triphosphate-Arrestin2
50.00	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
50.00	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on bk1_on
50.00	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2 8I95-C3a_B-EP54-Go/&β;1/&γ;2
50.00	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
50.00	Consensus	go_peptide	Orthosteric Ligand	go_opioid go_ghrelin go_compl-peptide go_galanin go_vasopressin
50.00	Consensus	gs_class-a	Orthosteric Ligand	gs_amine gs_nucleotide gs_lipid gs_peptide gs_protein gs_steroid
50.00	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
50.00	Consensus	opioid_on	Orthosteric Ligand	kop_on mop_on nop_on dop_on
50.00	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
48.15	Single	7YOO	Neuropeptide Y	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
48.00	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
48.00	Consensus	bk2_on	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
48.00	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
47.83	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
47.83	Consensus	gi_opioid	Orthosteric Ligand	8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 7U2K-μ-C6-guano-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2 8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 7SCG-μ-FH210-Gi1/&β;1/&γ;2 7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2 7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2 7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
47.83	Consensus	mop_off	Orthosteric Ligand	7UL4-μ-Alvimopan 4DKL-μ-Beta-funaltrexamine 8QOT-μ-Nanobody E
47.62	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
47.62	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
47.62	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
47.62	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
47.62	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2
47.62	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/&β;1/&γ;2
47.62	Consensus	dp2_off	Orthosteric Ligand	6D27-DP₂-CAY10471 6D26-DP₂-Fevipiprant
47.62	Consensus	dp_off	Orthosteric Ligand	dp2_off
47.62	Consensus	mop_on	Orthosteric Ligand	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
47.37	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
47.37	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/&β;1/&γ;2
47.37	Single	8X17	Namodenoson	8X17-A3A-Namodenoson-Gi1/&β;1/&γ;2
46.43	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
46.43	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
46.15	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2
46.15	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
46.15	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
46.15	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
46.15	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
46.15	Consensus	gs_bradykinin	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
45.83	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
45.83	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
45.45	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
45.45	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
45.45	Consensus	class-a_on	Orthosteric Ligand	sensory_on amine_on lipid_on nucleotide_on peptide_on protein_on hcar_on steroid_on melatonin_on
45.45	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
45.45	Consensus	gs_orexin	Orthosteric Ligand	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
45.45	Consensus	orexin_on	Orthosteric Ligand	ox2_on
45.00	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
45.00	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/&β;1/&γ;2
45.00	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/&β;1/&γ;2
45.00	Consensus	a1_on_allo	Orthosteric Ligand	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
45.00	Consensus	go_opioid	Orthosteric Ligand	8DZQ-κ-momSalB-Go/&β;1/&γ;2
44.83	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
44.44	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
44.44	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
44.44	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/&β;1/&γ;2
44.44	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
44.44	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
44.44	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
44.44	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
44.44	Consensus	gi_compl-peptide	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2 7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
44.44	Consensus	gi_neuromedin	Orthosteric Ligand	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
44.44	Consensus	gi_nucleotide	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
44.44	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
44.00	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
44.00	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2
44.00	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;2
44.00	Consensus	gs_motilin	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
43.48	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
43.48	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
43.48	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
43.48	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
43.48	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/&β;1/&γ;2
43.48	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2
43.48	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
43.48	Consensus	chemokine_on	Orthosteric Ligand	cxcr_on cx3cr_on
43.48	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_prostanoid gi_ffa gi_lpl gi_leukotriene
43.48	Consensus	motilin_on	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
42.86	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
42.86	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
42.86	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/&β;1/&γ;2
42.86	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/&β;1/&γ;2
42.86	Single	8ID6	Oleic acid	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2
42.86	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
42.86	Consensus	gi_dopamine	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
42.31	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
42.31	Single	7YON	Peptide YY(3-36)	7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
42.31	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
42.31	Consensus	gi_somatostatin	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XMT-SST4-J-2156-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
42.31	Consensus	nmur2_on	Orthosteric Ligand	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
42.11	Single	7F61	PF-03654746	7F61-H₃-PF-03654746-Cholesterol
42.11	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
42.11	Single	8UO2	Epinephrine	8UO2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
42.11	Consensus	gnrh_off	Orthosteric Ligand	gnrh1_off
42.11	Consensus	h3_on_allo	Orthosteric Ligand	7F61-H₃-PF-03654746-Cholesterol
41.94	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
41.67	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
41.67	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
41.67	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
41.67	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
41.67	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2
41.67	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin 8HN1-Alpha1A-Toxin AdTx1
41.67	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
41.67	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
41.67	Consensus	protein_off	Orthosteric Ligand	ccr_off chemokine_off gnrh_off
41.67	Consensus	sst_on	Orthosteric Ligand	sst2_on sst4_on
41.38	Single	8FEG	PRD_002517	8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
41.38	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2
41.38	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
41.38	Consensus	gs_endothelin	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
41.18	Single	7V6A	PubChem 9864275	7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
40.91	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
40.91	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
40.91	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
40.91	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
40.91	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
40.91	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2
40.91	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2
40.91	Single	8IBU	Erythromycin A	8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.91	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
40.91	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
40.91	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2
40.91	Consensus	go_5ht	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2 7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
40.91	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
40.91	Consensus	opioid_off	Orthosteric Ligand	kop_off mop_off nop_off dop_off
40.91	Consensus	peptide_off	Orthosteric Ligand	opioid_off angiotensin_off bombesin_off cck_off endothelin_off ghrelin_off npy_off nts_off orexin_off vasopressin-ot_off tachykinin_off sst_off
40.74	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.74	Single	7KH0	Acyclovir triphosphate	7KH0-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
40.74	Single	7X9B	Neuropeptide Y	7X9B-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
40.74	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
40.74	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/&β;1/&γ;2
40.74	Consensus	bk1_on	Orthosteric Ligand	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.74	Consensus	c5a1_on	Orthosteric Ligand	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2 8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
40.62	Consensus	gi_neuropeptide	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2 7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2 7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
40.62	Consensus	npy1_on	Orthosteric Ligand	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
40.62	Consensus	npy_on	Orthosteric Ligand	npy2_on npy4_on npy1_on
40.00	Single	4EJ4	Naltrindole	4EJ4-δ-Naltrindole
40.00	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
40.00	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
40.00	Single	6PS1	Timolol	6PS1-β₂-Timolol
40.00	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
40.00	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
40.00	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/&β;1/&γ;2
40.00	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
40.00	Single	7LJC	PubChem 86764103	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2
40.00	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/&β;1/&γ;2
40.00	Single	7T2G	Mitragynine pseudoindoxyl	7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2
40.00	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/&β;1/&γ;2
40.00	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
40.00	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
40.00	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
40.00	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2
40.00	Single	8GEH	Epinephrine	8GEH-β₂-Epinephrine-Gs/&β;1/&γ;2
40.00	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.00	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
40.00	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on
40.00	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off alpha1b_off
40.00	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
40.00	Consensus	cx3cr_on	Orthosteric Ligand	cx3cr1_on
40.00	Consensus	dop_off	Orthosteric Ligand	4EJ4-δ-Naltrindole
40.00	Consensus	gi_hca	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
40.00	Consensus	gi_hcar	Orthosteric Ligand	gi_hca
40.00	Consensus	gi_lpl	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2 7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
40.00	Consensus	hca2_on	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JHY-HCA₂-Compound 9n-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2 8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
40.00	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
40.00	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on
39.29	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
39.13	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
39.13	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/&β;1/&γ;2
39.13	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
39.13	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2
39.13	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/&β;1/&γ;2
39.13	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/&β;1/&γ;2
39.13	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
39.13	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/&β;1/&γ;2
39.13	Consensus	s1p1_on	Orthosteric Ligand	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
38.89	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
38.89	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
38.89	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
38.89	Consensus	go_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
38.89	Consensus	go_protein	Orthosteric Ligand	go_chemokine
38.71	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
38.46	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
38.46	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2
38.46	Consensus	cx3cr1_on	Orthosteric Ligand	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
38.46	Consensus	gi_chemerin	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
38.10	Single	5N2R	PubChem 92460631; psb36	5N2R-A_2A-PubChem 92460631; psb36-Na
38.10	Single	5N2S	PSB36	5N2S-A₁-PSB36
38.10	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
38.10	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
38.10	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/&β;1/&γ;2
38.10	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
38.10	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
38.10	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/&β;1/&γ;2
38.10	Single	7BB7	Acyclovir triphosphate	7BB7-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
38.10	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2
38.10	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/&β;1/&γ;2
38.10	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
38.10	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/&β;1/&γ;2
38.10	Single	7XKA	Epinephrine	7XKA-β₂-Epinephrine
38.10	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2
38.10	Single	8J19	PubChem 127045422	8J19-GPR84-PubChem 127045422-Gi1/&β;1/&γ;2
38.10	Single	8UNY	Epinephrine	8UNY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
38.10	Consensus	adrenergic_off	Orthosteric Ligand	beta_off alpha_off
38.10	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
37.93	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
37.93	Consensus	ccr8_on	Orthosteric Ligand	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
37.93	Consensus	etb_on	Orthosteric Ligand	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
37.50	Single	3NY9	PubChem 913103	3NY9-β₂-PubChem 913103
37.50	Single	6PT3	DPI-287	6PT3-δ-DPI-287
37.50	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2
37.50	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/&β;1/&γ;2
37.50	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/&β;1/&γ;2
37.50	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
37.50	Consensus	go_compl-peptide	Orthosteric Ligand	8I95-C3a_B-EP54-Go/&β;1/&γ;2 8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2 8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2
37.50	Consensus	go_ghrelin	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
37.50	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2 7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
37.50	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
37.50	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
37.50	Consensus	nk1_on	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
37.50	Consensus	protein_on	Orthosteric Ligand	ccr_on chemokine_on gphr_on chemerin_on
37.04	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
37.04	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
37.04	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
37.04	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
37.04	Single	7DW9	Acyclovir triphosphate	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
37.04	Consensus	ghrelin_on	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
37.04	Consensus	nmur_on	Orthosteric Ligand	nmur1_on nmur2_on
37.04	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
36.84	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
36.84	Single	6AKX	A4R	6AKX-CCR5-A4R
36.84	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
36.84	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
36.84	Single	7EJ0	L-Norepinephrine	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2
36.84	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
36.84	Single	7T94	PubChem 57664406	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
36.84	Single	8EFO	PZM21	8EFO-μ-PZM21-Gi1/&β;1/&γ;2
36.84	Single	8GGF	Epinephrine	8GGF-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
36.84	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/&β;1/&γ;2
36.84	Single	8UO0	Epinephrine	8UO0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
36.84	Single	8UO3	Epinephrine	8UO3-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
36.84	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
36.84	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
36.84	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
36.84	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
36.84	Consensus	m2_on_allo	Other Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
36.84	Consensus	p2y_off	Orthosteric Ligand	p2y1_off p2y12_off
36.67	Single	7VGX	Neuropeptide Y	7VGX-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
36.67	Consensus	gi_chemokine	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2 7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2 7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2 7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2 8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2 6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2 8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
36.36	Single	2YDV	NECA	2YDV-A_2A-NECA
36.36	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
36.36	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
36.36	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
36.36	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
36.36	Single	5G53	NECA	5G53-A_2A-NECA-Gs
36.36	Single	6OS1	TRV026	6OS1-AT₁-TRV026
36.36	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
36.36	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
36.36	Single	7EW7	PubChem 4077460	7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
36.36	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/&β;1/&γ;2
36.36	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/&β;1/&γ;2
36.36	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2
36.36	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2
36.36	Single	7X9A	Neuropeptide Y	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
36.36	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/&β;1/&γ;2
36.36	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2
36.36	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/&β;1/&γ;2
36.36	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
36.36	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
36.36	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2
36.36	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/&β;1/&γ;2
36.36	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/&β;1/&γ;2
36.36	Single	8X16	Piclidenoson	8X16-A3A-Piclidenoson-Gi1/&β;1/&γ;2
36.36	Consensus	5ht1b_on	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
36.36	Consensus	a2_on	Orthosteric Ligand	a2a_on a2b_on
36.36	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
36.36	Consensus	class-a_off	Orthosteric Ligand	sensory_off amine_off lipid_off nucleotide_off peptide_off protein_off hcar_off
36.36	Consensus	dopamine_off	Orthosteric Ligand	d3_off d2_off d4_off
36.36	Consensus	ffa4_on	Orthosteric Ligand	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
36.36	Consensus	gi_muscarinic	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
36.36	Consensus	gs_compl-peptide	Orthosteric Ligand	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
36.36	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2
36.36	Consensus	gs_ffa	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2 8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
36.36	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
36.00	Single	5VBL	Apelin Mimetic Peptide Agonist	5VBL-Apelin-Apelin Mimetic Peptide Agonist
36.00	Single	7RMH	Substance P	7RMH-NK₁-Substance P-Gs/&β;1/&γ;2
36.00	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
36.00	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
36.00	Single	8GHV	PubChem 145964903	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
36.00	Consensus	fpr-alx_on	Orthosteric Ligand	fpr1-alx_on fpr2-alx_on
36.00	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
35.71	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
35.71	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
35.71	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2
35.71	Consensus	gs_ghrelin	Orthosteric Ligand	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
35.71	Consensus	gs_neuromedin	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
35.71	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
35.48	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
35.48	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
35.29	Single	8DPH	Lorcaserin	8DPH-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
35.00	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
35.00	Single	4DKL	Beta-funaltrexamine	4DKL-μ-Beta-funaltrexamine
35.00	Single	4LDO	L-Epinephrine	4LDO-β₂-L-Epinephrine
35.00	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
35.00	Single	4N6H	Naltrindole	4N6H-δ-Naltrindole-Na
35.00	Single	4ZJC	SB-674042	4ZJC-OX₁-SB-674042
35.00	Single	5K2B	ZM241385	5K2B-A_2A-ZM241385-Na
35.00	Single	5NLX	ZM241385	5NLX-A_2A-ZM241385-Na
35.00	Single	6DS0	Ly266097	6DS0-5-HT_2B-Ly266097
35.00	Single	6K41	Dexmedetomidine	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
35.00	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
35.00	Single	6MH8	ZM241385	6MH8-A_2A-ZM241385
35.00	Single	6PS4	ICI 118-551	6PS4-β₂-ICI 118-551
35.00	Single	6TPG	EMPA	6TPG-OX₂-EMPA
35.00	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
35.00	Single	7BB6	Acyclovir triphosphate	7BB6-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
35.00	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
35.00	Single	7CMU	Pramipexole	7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
35.00	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2
35.00	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
35.00	Single	7RAN	PubChem 164575847	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
35.00	Single	7SR8	TAK-925	7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
35.00	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
35.00	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/&β;1/&γ;2
35.00	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
35.00	Single	8GEG	Epinephrine	8GEG-β₂-Epinephrine-Gs/&β;1/&γ;2
35.00	Single	8GGQ	Epinephrine	8GGQ-β₂-Epinephrine
35.00	Single	8GGT	Epinephrine	8GGT-β₂-Epinephrine
35.00	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2
35.00	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/&β;1/&γ;2
35.00	Single	8THL	Epinephrine	8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
35.00	Single	8UNZ	Epinephrine	8UNZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
35.00	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2
35.00	Consensus	alpha2b_on	Orthosteric Ligand	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
35.00	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
35.00	Consensus	cxcr_on	Orthosteric Ligand	cxcr1_on cxcr2_on
35.00	Consensus	d1_on_allo	Orthosteric Ligand	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2 7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
35.00	Consensus	d3_on	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
35.00	Consensus	dop_off_allo	Orthosteric Ligand	4N6H-δ-Naltrindole-Na
35.00	Consensus	gs_tar	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2 8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
35.00	Consensus	hca_on	Orthosteric Ligand	hca2_on hca3_on
35.00	Consensus	hcar_on	Orthosteric Ligand	hca_on
35.00	Consensus	ox1_off	Orthosteric Ligand	6TOT-OX₁-Lemborexant 6TP4-OX₁-ACT-462206 6TP6-OX₁-Filorexant 6V9S-OX₁-GTPL11403 6TP3-OX₁-Nemorexant 6TQ6-OX₁-PubChem 145714283 6TQ7-OX₁-SB-334867 6TQ9-OX₁-SB-408124 4ZJC-OX₁-SB-674042 4ZJ8-OX₁-Suvorexant
35.00	Consensus	ox2_off	Orthosteric Ligand	6TPN-OX₂-HTL6641 7XRR-OX₂-Lemborexant
34.78	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
34.78	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
34.78	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
34.78	Single	6OS2	TRV026	6OS2-AT₁-TRV026
34.78	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/&β;1/&γ;2
34.78	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
34.78	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
34.78	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
34.78	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2
34.78	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/&β;1/&γ;2
34.78	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
34.78	Single	7L1V	PubChem 155491009	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
34.78	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
34.78	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/&β;1/&γ;2
34.78	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
34.78	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/&β;1/&γ;2
34.78	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
34.78	Single	8I95	EP54	8I95-C3a_B-EP54-Go/&β;1/&γ;2
34.78	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2
34.78	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
34.78	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
34.78	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/&β;1/&γ;2
34.78	Single	8T3Q	DHA	8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
34.78	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
34.78	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_muscarinic gs_tar
34.78	Consensus	gs_bileacid	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
34.78	Consensus	gs_steroid	Orthosteric Ligand	gs_bileacid
34.78	Consensus	gs_trh	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
34.78	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z34-LPA₁-ONO-9780307 4Z35-LPA₁-ONO-9910539 7YU4-LPA₁-ONO-0740556
34.78	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
34.62	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
34.62	Single	8F7Q	Beta-endorphin	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2
34.48	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
34.48	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
34.48	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
34.48	Consensus	bb1_on	Orthosteric Ligand	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
34.48	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
34.48	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
34.38	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
34.38	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
34.38	Consensus	melanocortin_on	Orthosteric Ligand	mc2_on mc1_on mc3_on mc4_on mc5_on
33.33	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
33.33	Single	3EML	ZM241385	3EML-A_2A-ZM241385
33.33	Single	3NY8	ICI 118-551	3NY8-β₂-ICI 118-551
33.33	Single	3NYA	(S)-Alprenolol	3NYA-β₂-(S)-Alprenolol
33.33	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
33.33	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
33.33	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
33.33	Single	4GBR	(S)-Carazolol	4GBR-β₂-(S)-Carazolol
33.33	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
33.33	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
33.33	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
33.33	Single	5JQH	(S)-Carazolol	5JQH-β₂-(S)-Carazolol
33.33	Single	5K2A	ZM241385	5K2A-A_2A-ZM241385-Na
33.33	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
33.33	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
33.33	Single	5VRA	ZM241385	5VRA-A_2A-ZM241385-Na
33.33	Single	6D27	CAY10471	6D27-DP₂-CAY10471
33.33	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
33.33	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
33.33	Single	6K42	Dexmedetomidine	6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
33.33	Single	6LPJ	ZM241385	6LPJ-A_2A-ZM241385-Na
33.33	Single	6LPK	ZM241385	6LPK-A_2A-ZM241385-Na
33.33	Single	6PS0	(S)-Carazolol	6PS0-β₂-(S)-Carazolol
33.33	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
33.33	Single	6S0L	ZM241385	6S0L-A_2A-ZM241385
33.33	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
33.33	Single	7BTS	L-Epinephrine	7BTS-β₁-L-Epinephrine
33.33	Single	7BU6	L-Norepinephrine	7BU6-β₁-L-Norepinephrine
33.33	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2
33.33	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2
33.33	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2
33.33	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2
33.33	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
33.33	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
33.33	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
33.33	Single	7F53	Alpha-MSH	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2
33.33	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
33.33	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1
33.33	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
33.33	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
33.33	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
33.33	Single	7O7F	(6P4)CCL5	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1
33.33	Single	7P00	Substance P	7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Single	7S0G	Isoprenaline	7S0G-β₁-Isoprenaline-chim(Gi1-CtGs)/&β;1/&γ;2
33.33	Single	7SCG	FH210	7SCG-μ-FH210-Gi1/&β;1/&γ;2
33.33	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/&β;1/&γ;2
33.33	Single	7UL4	Alvimopan	7UL4-μ-Alvimopan
33.33	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
33.33	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2
33.33	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
33.33	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2
33.33	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
33.33	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
33.33	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
33.33	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2
33.33	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/&β;1/&γ;2
33.33	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
33.33	Single	8GE3	Epinephrine	8GE3-β₂-Epinephrine-Gs/&β;1/&γ;2
33.33	Single	8GEB	Epinephrine	8GEB-β₂-Epinephrine-Gs/&β;1/&γ;2
33.33	Single	8GEE	Epinephrine	8GEE-β₂-Epinephrine-Gs/&β;1/&γ;2
33.33	Single	8GFW	Epinephrine	8GFW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8GFX	Epinephrine	8GFX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8GFY	Epinephrine	8GFY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8GFZ	Epinephrine	8GFZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8GG0	Epinephrine	8GG0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8GG1	Epinephrine	8GG1-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8GG2	Epinephrine	8GG2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8GG6	Epinephrine	8GG6-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8GGB	Epinephrine	8GGB-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8GGJ	Epinephrine	8GGJ-β₂-Epinephrine
33.33	Single	8GGN	Epinephrine	8GGN-β₂-Epinephrine
33.33	Single	8GGO	Epinephrine	8GGO-β₂-Epinephrine
33.33	Single	8GGU	Epinephrine	8GGU-β₂-Epinephrine
33.33	Single	8IRT	Rotigotine	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2
33.33	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
33.33	Single	8JJO	Alprenolol	8JJO-β₂-Alprenolol
33.33	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
33.33	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
33.33	Single	8UNM	Epinephrine	8UNM-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8UNN	Epinephrine	8UNN-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8UNP	Epinephrine	8UNP-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
33.33	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2
33.33	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2
33.33	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
33.33	Single	8WC9	ZH8651	8WC9-TA1-ZH8651-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/&β;1/&γ;2
33.33	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
33.33	Consensus	adrenergic_on	Orthosteric Ligand	beta_on alpha_on
33.33	Consensus	alpha2_on	Orthosteric Ligand	alpha2a_on alpha2b_on
33.33	Consensus	alpha_on	Orthosteric Ligand	alpha1_on alpha2_on
33.33	Consensus	beta1_off_allo	Orthosteric Ligand	4BVN-β₁-Cyanopindolol-Na
33.33	Consensus	bileacid_on	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
33.33	Consensus	c5a1_off_ortoallo	Orthosteric Ligand	6C1Q-C5a₁-PMX53-NDT9513727 6C1R-C5a₁-PMX53-Avacopan; Na
33.33	Consensus	cck_off	Orthosteric Ligand	ccka_off
33.33	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
33.33	Consensus	cckb_on	Orthosteric Ligand	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
33.33	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
33.33	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
33.33	Consensus	dopamine_on	Orthosteric Ligand	d3_on d2_on d5_on d1_on
33.33	Consensus	endothelin_off	Orthosteric Ligand	etb_off
33.33	Consensus	etb_off	Orthosteric Ligand	5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500 5X93-ET_B-K-8794
33.33	Consensus	fsh_on_allo	Other Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
33.33	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
33.33	Consensus	gi_formylpeptide	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2 7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
33.33	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
33.33	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
33.33	Consensus	gs_tachykinin	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Consensus	hca3_on	Orthosteric Ligand	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
33.33	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off leuko_off lpl_off paf_off prostanoid_off
33.33	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
33.33	Consensus	smo_off	Orthosteric Ligand	5L7I-SMO-Vismodegib 4O9R-SMO-Cyclopamine 4QIM-SMO-PubChem 24905375 4JKV-SMO-Taladegib (LY2940680)
33.33	Consensus	steroid_on	Orthosteric Ligand	bileacid_on
33.33	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on
33.33	Consensus	tar_on	Orthosteric Ligand	ta1_on
32.35	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
32.14	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2
32.14	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
32.14	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/&β;1/&γ;2
32.14	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
32.14	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/&β;1/&γ;2
32.14	Consensus	ccr1_on	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
32.00	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
32.00	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
32.00	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
32.00	Single	7RMG	Substance P	7RMG-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
32.00	Single	7XY6	PubChem 11717831	7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
32.00	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
32.00	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2
32.00	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
32.00	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
32.00	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
32.00	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
32.00	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on gpr119_on leuko_on lpl_on prostanoid_on
32.00	Consensus	mc4_on	Orthosteric Ligand	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
31.82	Single	2RH1	(S)-Carazolol	2RH1-β₂-(S)-Carazolol
31.82	Single	2YCW	(S)-Carazolol	2YCW-β₁-(S)-Carazolol
31.82	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
31.82	Single	5D6L	(S)-Carazolol	5D6L-β₂-(S)-Carazolol
31.82	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
31.82	Single	5NM2	ZM241385	5NM2-A_2A-ZM241385-Na
31.82	Single	5WQC	EMPA	5WQC-OX₂-EMPA
31.82	Single	5X7D	(S)-Carazolol	5X7D-β₂-(S)-Carazolol-PubChem 129318963
31.82	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
31.82	Single	6KUW	PubChem 57213234	6KUW-α_2c-PubChem 57213234
31.82	Single	6LPL	ZM241385	6LPL-A_2A-ZM241385-Na
31.82	Single	6PS3	(S)-Carvedilol	6PS3-β₂-(S)-Carvedilol
31.82	Single	6PS6	Timolol	6PS6-β₂-Timolol
31.82	Single	6S0Q	ZM241385	6S0Q-A_2A-ZM241385
31.82	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
31.82	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
31.82	Single	6WQA	ZM241385	6WQA-A_2A-ZM241385-Na
31.82	Single	7BVQ	(S)-Carazolol	7BVQ-β₁-(S)-Carazolol
31.82	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/&β;1/&γ;2
31.82	Single	7RM5	ZM241385	7RM5-A_2A-ZM241385-Na
31.82	Single	7S0F	Isoprenaline	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2
31.82	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/&β;1/&γ;2
31.82	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2
31.82	Single	7WC6	LSD	7WC6-5-HT_2A-LSD
31.82	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
31.82	Single	7Y27	Somatostatin-14	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
31.82	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
31.82	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2
31.82	Single	8FN1	Neurotensin/neuromedin N	8FN1-NTS₁-Neurotensin/neuromedin N-chim(NtGi1-Go)/&β;1/&γ;2
31.82	Single	8FYN	ZM241385	8FYN-A_2A-ZM241385-Na
31.82	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
31.82	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
31.82	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
31.82	Single	8JPC	Neurotensin 8-13	8JPC-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
31.82	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/&β;1/&γ;2
31.82	Single	8QOT	Nanobody E	8QOT-μ-Nanobody E
31.82	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide 6DRX-5-HT_2B-Lisuride
31.82	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
31.82	Consensus	a2a_on	Orthosteric Ligand	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
31.82	Consensus	alpha2a_on	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
31.82	Consensus	alpha2c_off	Orthosteric Ligand	6KUW-α_2c-PubChem 57213234
31.82	Consensus	amine_off	Orthosteric Ligand	adrenergic_off histamine_off muscarinic_off 5ht_off dopamine_off
31.82	Consensus	beta2_off	Orthosteric Ligand	6PS2-β₂-(S)-Alprenolol 6PS3-β₂-(S)-Carvedilol 6PS5-β₂-(S)-Propranolol 6PS6-β₂-Timolol 2RH1-β₂-(S)-Carazolol 6PS4-β₂-ICI 118-551 3NY9-β₂-PubChem 913103
31.82	Consensus	beta2_on	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
31.82	Consensus	beta_off	Orthosteric Ligand	beta1_off beta2_off
31.82	Consensus	cb2_on	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
31.82	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
31.82	Consensus	gi_adrenergic	Orthosteric Ligand	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2 6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
31.82	Consensus	go_amine	Orthosteric Ligand	go_adrenergic go_muscarinic go_5ht
31.82	Consensus	gs_adrenergic	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2 7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJI-β₃-Solabegron-Gs/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
31.82	Consensus	gs_sst	Orthosteric Ligand	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
31.82	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2 8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2 8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
31.58	Single	7EJK	Oxymetazoline	7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2
31.58	Single	7SRQ	LSD	7SRQ-5-HT_2B-LSD
31.58	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/&β;1/&γ;2
31.58	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/&β;1/&γ;2
31.58	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2
31.58	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/&β;1/&γ;2
31.58	Single	8GEI	Epinephrine	8GEI-β₂-Epinephrine-Gs/&β;1/&γ;2
31.58	Single	8GGC	Epinephrine	8GGC-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
31.58	Single	8GGE	Epinephrine	8GGE-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
31.58	Single	8GH1	Epinephrine	8GH1-β₂-Epinephrine
31.58	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2
31.58	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/&β;1/&γ;2
31.58	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/&β;1/&γ;2
31.58	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/&β;1/&γ;2
31.58	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2
31.58	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2
31.58	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
31.58	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2
31.58	Single	8WC3	SEP-363856	8WC3-TA1-SEP-363856-chim(NtGi1-Gs)/&β;1/&γ;2
31.58	Consensus	m4_on_allo	Other Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
31.03	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/&β;1/&γ;2
31.03	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
31.03	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2
31.03	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2
31.03	Consensus	bombesin_on	Orthosteric Ligand	bb2_on bb1_on
31.03	Consensus	gs_melanocortin	Orthosteric Ligand	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2 7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2
30.77	Single	4AMJ	(S)-Carvedilol	4AMJ-β₁-(S)-Carvedilol
30.77	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
30.77	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
30.77	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
30.77	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
30.77	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
30.77	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/&β;1/&γ;2
30.77	Consensus	nmur1_on	Orthosteric Ligand	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
30.43	Single	3P0G	BI167107	3P0G-β₂-BI167107
30.43	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/&β;1/&γ;2
30.43	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
30.43	Single	4DJH	JDTic	4DJH-κ-JDTic
30.43	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
30.43	Single	5D5A	(S)-Carazolol	5D5A-β₂-(S)-Carazolol
30.43	Single	5D5B	(S)-Carazolol	5D5B-β₂-(S)-Carazolol
30.43	Single	5X93	K-8794	5X93-ET_B-K-8794
30.43	Single	6H7J	Isoprenaline	6H7J-β₁-Isoprenaline
30.43	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
30.43	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
30.43	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
30.43	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/&β;1/&γ;2
30.43	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
30.43	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
30.43	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
30.43	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
30.43	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/&β;1/&γ;2
30.43	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2
30.43	Single	7JJO	Isoprenaline	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2
30.43	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/&β;1/&γ;2
30.43	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
30.43	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
30.43	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
30.43	Single	7R0C	Acyclovir triphosphate	7R0C-V₂-Acyclovir triphosphate-Arrestin2
30.43	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
30.43	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
30.43	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2
30.43	Single	7W6P	W96	7W6P-α_2a-W96-Go/&β;1/&γ;2
30.43	Single	7W7E	W58	7W7E-α_2a-W58-Go/&β;1/&γ;2
30.43	Single	7WV9	PubMed 104895	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
30.43	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
30.43	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
30.43	Single	7XOX	Cholecystokinin-8	7XOX-CCK_B-Cholecystokinin-8-Gq/&β;1/&γ;2
30.43	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
30.43	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/&β;1/&γ;2
30.43	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2
30.43	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/&β;1/&γ;2
30.43	Single	8FMZ	Neurotensin/neuromedin N	8FMZ-NTS₁-Neurotensin/neuromedin N-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
30.43	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
30.43	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2
30.43	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2
30.43	Single	8IRR	Rotigotine	8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2
30.43	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/&β;1/&γ;2
30.43	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/&β;1/&γ;2
30.43	Consensus	5ht_off	Orthosteric Ligand	5ht2_off 5ht5_off 5ht1_off
30.43	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
30.43	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
30.43	Consensus	alpha1b_off	Orthosteric Ligand	7B6W-α_1b-Cyclazosin
30.43	Consensus	angiotensin_off	Orthosteric Ligand	at1_off at2_off
30.43	Consensus	beta1_off	Orthosteric Ligand	2VT4-β₁-Cyanopindolol 2YCZ-β₁-Iodocyanopindolol
30.43	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
30.43	Consensus	cml1_on	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
30.43	Consensus	cyslt1_off_ortoallo	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
30.43	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_adrenergic gi_dopamine gi_muscarinic gi_histamine
30.43	Consensus	gi_ffa	Orthosteric Ligand	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2 8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
30.43	Consensus	go_adrenergic	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
30.43	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 6GDG-A_2A-NECA-Gs/&β;1/&γ;1 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
30.43	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
30.43	Consensus	h1_off	Orthosteric Ligand	3RZE-H₁-Cidoxepin 8X5Y-H₁-Astemizole 8X63-H₁-Mepyramine 8X64-H₁-Desloratadine
30.43	Consensus	histamine_off	Orthosteric Ligand	h1_off
30.43	Consensus	kop_off	Orthosteric Ligand	4DJH-κ-JDTic
30.43	Consensus	lpa1_on	Orthosteric Ligand	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
30.43	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
30.43	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
30.43	Consensus	npy_off	Orthosteric Ligand	npy2_off npy1_off
30.43	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
30.00	Single	2X72	All-trans-retinal	2X72-Rhodopsin-All-trans-retinal-Gt(CT)
30.00	Single	3VGA	ZM241385	3VGA-A_2A-ZM241385-Antibody
30.00	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
30.00	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
30.00	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
30.00	Single	5K2D	ZM241385	5K2D-A_2A-ZM241385
30.00	Single	5WS3	EMPA	5WS3-OX₂-EMPA
30.00	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
30.00	Single	6B73	PubChem 131955138	6B73-κ-PubChem 131955138
30.00	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/&β;1/&γ;2
30.00	Single	6FJ3	PTH	6FJ3-PTH1-PTH
30.00	Single	6JZH	ZM241385	6JZH-A_2A-ZM241385-Na
30.00	Single	6KUY	PubChem 145704643	6KUY-α_2a-PubChem 145704643
30.00	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
30.00	Single	6PS7	ZM241385	6PS7-A_2A-ZM241385-Na
30.00	Single	6TOD	EMPA	6TOD-OX₁-EMPA-Na
30.00	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
30.00	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/&β;1/&γ;2
30.00	Single	7F24	Dopamine	7F24-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
30.00	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
30.00	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
30.00	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
30.00	Single	7SRR	LSD	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
30.00	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
30.00	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
30.00	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/&β;1/&γ;2
30.00	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/&β;1/&γ;2
30.00	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
30.00	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/&β;1/&γ;2
30.00	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
30.00	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
30.00	Single	7YM8	Oxymetazoline	7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2
30.00	Single	7YMH	Norepinephrine	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2
30.00	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/&β;1/&γ;2
30.00	Single	8GEC	Epinephrine	8GEC-β₂-Epinephrine-Gs/&β;1/&γ;2
30.00	Single	8GEF	Epinephrine	8GEF-β₂-Epinephrine-Gs/&β;1/&γ;2
30.00	Single	8GG9	Epinephrine	8GG9-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
30.00	Single	8GGA	Epinephrine	8GGA-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
30.00	Single	8GGV	Epinephrine	8GGV-β₂-Epinephrine
30.00	Single	8GGW	Epinephrine	8GGW-β₂-Epinephrine
30.00	Single	8GGX	Epinephrine	8GGX-β₂-Epinephrine
30.00	Single	8GH0	Epinephrine	8GH0-β₂-Epinephrine
30.00	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2
30.00	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/&β;1/&γ;2
30.00	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
30.00	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2
30.00	Single	8IW4	Spermidine	8IW4-TAAR9-Spermidine-chim(NtGi1-Gs)/&β;1/&γ;2
30.00	Single	8IWE	Spermidine	8IWE-TAAR9-Spermidine
30.00	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/&β;1/&γ;2
30.00	Single	8UNW	Epinephrine	8UNW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
30.00	Consensus	5ht2_on	Orthosteric Ligand	5ht2a_on 5ht2c_on
30.00	Consensus	alpha1_on	Orthosteric Ligand	alpha1a_on
30.00	Consensus	alpha1a_on	Orthosteric Ligand	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2 7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
30.00	Consensus	alpha2_off	Orthosteric Ligand	alpha2a_off alpha2c_off
30.00	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
30.00	Consensus	gi_histamine	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/&β;1/&γ;2 8HOC-H₄-Imetit-Gi1/&β;1/&γ;2
30.00	Consensus	gs_histamine	Orthosteric Ligand	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
30.00	Consensus	gs_vasopressin-ot	Orthosteric Ligand	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
30.00	Consensus	h4_on	Orthosteric Ligand	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
30.00	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
30.00	Consensus	orexin_off	Orthosteric Ligand	ox2_off ox1_off
29.63	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
29.63	Single	7RMI	Substance P	7RMI-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
29.63	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
29.63	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
29.63	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
29.63	Consensus	vasopressin-ot_on	Orthosteric Ligand	ot_on v2_on
29.41	Single	7V68	PubChem 57664406	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
29.17	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
29.17	Single	3D4S	Timolol Maleate	3D4S-β₂-Timolol Maleate
29.17	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
29.17	Single	4GRV	Neurotensin 8-13	4GRV-NTS₁-Neurotensin 8-13
29.17	Single	4LDE	BI167107	4LDE-β₂-BI167107
29.17	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
29.17	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
29.17	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
29.17	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
29.17	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
29.17	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
29.17	Single	6H7O	Cyanopindolol	6H7O-β₁-Cyanopindolol
29.17	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
29.17	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
29.17	Single	6ZG4	HTL0009936	6ZG4-M₁-HTL0009936
29.17	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2
29.17	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
29.17	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
29.17	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/&β;1/γ1
29.17	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
29.17	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
29.17	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
29.17	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2
29.17	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
29.17	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
29.17	Single	8WU1	KCA	8WU1-CB₁-KCA-Arrestin1
29.17	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
29.17	Consensus	at2_off	Orthosteric Ligand	7JNI-AT₂-Olodanrigan
29.17	Consensus	cannabinoid_off	Orthosteric Ligand	cb1_off cb2_off
29.17	Consensus	cannabinoid_on	Orthosteric Ligand	cb1_on cb2_on
29.17	Consensus	cb1_on	Orthosteric Ligand	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
29.17	Consensus	chemokine_off	Orthosteric Ligand	cxcr_off
29.17	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II
29.17	Consensus	cxcr_off	Orthosteric Ligand	cxcr4_off
29.17	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
29.17	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2 8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
29.17	Consensus	gi_class-f	Other Ligand	gi_frizzled
29.17	Consensus	gi_frizzled	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
29.17	Consensus	leuko_off	Orthosteric Ligand	blt_off cyslt_off
29.17	Consensus	s1p_on	Orthosteric Ligand	s1p3_on s1p5_on s1p1_on s1p2_on
29.17	Consensus	tsh_on_allo	Other Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
29.03	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
29.03	Consensus	ccr_on	Orthosteric Ligand	ccr5_on ccr6_on ccr1_on ccr2_on ccr8_on
28.57	Single	3UZC	PubChem 135566609	3UZC-A_2A-PubChem 135566609
28.57	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
28.57	Single	5IU4	ZM241385	5IU4-A_2A-ZM241385-Na
28.57	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
28.57	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
28.57	Single	5JTB	ZM241385	5JTB-A_2A-ZM241385
28.57	Single	5K2C	ZM241385	5K2C-A_2A-ZM241385-Na
28.57	Single	5NM4	ZM241385	5NM4-A_2A-ZM241385-Na
28.57	Single	5UVI	ZM241385	5UVI-A_2A-ZM241385
28.57	Single	6IQL	L745870	6IQL-D₄-L745870
28.57	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
28.57	Single	6PS5	(S)-Propranolol	6PS5-β₂-(S)-Propranolol
28.57	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
28.57	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
28.57	Single	6V9S	GTPL11403	6V9S-OX₁-GTPL11403
28.57	Single	6VI4	JDTic	6VI4-κ-JDTic
28.57	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
28.57	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
28.57	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
28.57	Single	6ZFZ	77-LH-28-1	6ZFZ-M₁-77-LH-28-1
28.57	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/&β;1/&γ;2
28.57	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/&β;1/&γ;2
28.57	Single	7DHI	Salbutamol	7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
28.57	Single	7E33	BRL-54443	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
28.57	Single	7F4D	Alpha-MSH	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2
28.57	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/&β;1/&γ;2
28.57	Single	7T32	ZM241385	7T32-A_2A-ZM241385
28.57	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
28.57	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
28.57	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2
28.57	Single	7UM7	Methylergometrine	7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
28.57	Single	7XJJ	Galanin	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
28.57	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
28.57	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.57	Single	8GDZ	Epinephrine	8GDZ-β₂-Epinephrine-Gs/&β;1/&γ;2
28.57	Single	8GE1	Epinephrine	8GE1-β₂-Epinephrine-Gs/&β;1/&γ;2
28.57	Single	8GE4	Epinephrine	8GE4-β₂-Epinephrine-Gs/&β;1/&γ;2
28.57	Single	8GE6	Epinephrine	8GE6-β₂-Epinephrine-Gs/&β;1/&γ;2
28.57	Single	8GE7	Epinephrine	8GE7-β₂-Epinephrine-Gs/&β;1/&γ;2
28.57	Single	8GE8	Epinephrine	8GE8-β₂-Epinephrine-Gs/&β;1/&γ;2
28.57	Single	8GE9	Epinephrine	8GE9-β₂-Epinephrine-Gs/&β;1/&γ;2
28.57	Single	8GFV	Epinephrine	8GFV-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
28.57	Single	8GG3	Epinephrine	8GG3-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
28.57	Single	8GG4	Epinephrine	8GG4-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
28.57	Single	8GG5	Epinephrine	8GG5-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
28.57	Single	8GG8	Epinephrine	8GG8-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
28.57	Single	8GGI	Epinephrine	8GGI-β₂-Epinephrine
28.57	Single	8GGK	Epinephrine	8GGK-β₂-Epinephrine
28.57	Single	8GGM	Epinephrine	8GGM-β₂-Epinephrine
28.57	Single	8GGP	Epinephrine	8GGP-β₂-Epinephrine
28.57	Single	8GUR	PubChem 104895	8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2
28.57	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/&β;1/&γ;2
28.57	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
28.57	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/&β;1/&γ;2
28.57	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/&β;1/&γ;2
28.57	Single	8JLN	T1AM	8JLN-TA1-T1AM-Gs/&β;1/&γ;2
28.57	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2
28.57	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
28.57	Single	8THK	A61603	8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.57	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/&β;1/&γ;2
28.57	Single	8UNQ	Epinephrine	8UNQ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
28.57	Single	8UNR	Epinephrine	8UNR-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
28.57	Single	8UNS	Epinephrine	8UNS-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
28.57	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/&β;1/&γ;2
28.57	Consensus	5ht1e_on	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
28.57	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6WH4-5-HT_2A-Methiothepin 7VOE-5-HT_2A-Aripiprazole 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 6A93-5-HT_2A-Risperidone
28.57	Consensus	5ht2a_on	Orthosteric Ligand	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.57	Consensus	5ht5_on	Orthosteric Ligand	5ht5a_on
28.57	Consensus	5ht5a_on	Orthosteric Ligand	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
28.57	Consensus	ccr_off	Orthosteric Ligand	ccr5_off ccr8_off
28.57	Consensus	ffa2_on	Orthosteric Ligand	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
28.57	Consensus	go_galanin	Orthosteric Ligand	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
28.57	Consensus	lh_on_allo	Other Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
28.57	Consensus	m1_off_allo	Other Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
28.57	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-PubChem 25001412 5DHH-NOP-SB-612111
28.57	Consensus	s1p1_off	Orthosteric Ligand	3V2Y-S1P₁-PubChem 51892645
28.57	Consensus	s1p_off	Orthosteric Ligand	s1p1_off
28.12	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2
28.00	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
28.00	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
28.00	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
28.00	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
28.00	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
28.00	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
28.00	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
28.00	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2
28.00	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
28.00	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
28.00	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/&β;1/&γ;2
28.00	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/&β;1/&γ;2
28.00	Single	8E9Y	PubChem 446603	8E9Y-M₃-PubChem 446603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.00	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2
28.00	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
28.00	Single	8ID8	TUG-891	8ID8-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
28.00	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
28.00	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
28.00	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/&β;1/&γ;2
28.00	Single	8WRZ	8D0	8WRZ-CB₁-8D0-Arrestin1
28.00	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
28.00	Consensus	gi_neurotensin	Orthosteric Ligand	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1 6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
28.00	Consensus	ot_on	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
27.78	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
27.78	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
27.78	Single	8IWM	2-Phenylethylamine	8IWM-TAAR9-2-Phenylethylamine
27.78	Single	8WC5	Tetramethylammonium ion	8WC5-TA1-Tetramethylammonium ion-chim(NtGi1-Gs)/&β;1/&γ;2
27.78	Consensus	hca2_on_allo	Orthosteric Ligand	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2 8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
27.59	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
27.59	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
27.59	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2
27.59	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/&β;1/&γ;2
27.50	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
27.27	Single	2VT4	Cyanopindolol	2VT4-β₁-Cyanopindolol
27.27	Single	2Y02	Carmoterol	2Y02-β₁-Carmoterol
27.27	Single	2Y04	Salbutamol	2Y04-β₁-Salbutamol
27.27	Single	2YCY	Cyanopindolol	2YCY-β₁-Cyanopindolol
27.27	Single	3ZPQ	4-(piperazin-1- yl)-1H-indole	3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na
27.27	Single	3ZPR	4-methyl-2-(piperazin-1-yl)	3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
27.27	Single	4EIY	ZM241385	4EIY-A_2A-ZM241385-Na
27.27	Single	4QIM	PubChem 24905375	4QIM-SMO-PubChem 24905375
27.27	Single	4QKX	PubChem 76210628	4QKX-β₂-PubChem 76210628
27.27	Single	4U16	N-Methyl Scopolamine	4U16-M₃-N-Methyl Scopolamine
27.27	Single	4X1H	Nonyl Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl Beta-D-Glucopyranoside-Gt(CT)
27.27	Single	5DHG	PubChem 25001412	5DHG-NOP-PubChem 25001412
27.27	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
27.27	Single	5OLG	ZM241385	5OLG-A_2A-ZM241385-Na
27.27	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
27.27	Single	5UEN	DU172	5UEN-A₁-DU172
27.27	Single	5YC8	N-Methyl Scopolamine	5YC8-M₂-N-Methyl Scopolamine
27.27	Single	5ZK8	N-Methyl Scopolamine	5ZK8-M₂-N-Methyl Scopolamine
27.27	Single	5ZKC	N-Methyl Scopolamine	5ZKC-M₂-N-Methyl Scopolamine
27.27	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
27.27	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
27.27	Single	6H7M	Salbutamol	6H7M-β₁-Salbutamol
27.27	Single	6PRZ	(S)-Alprenolol	6PRZ-β₂-(S)-Alprenolol
27.27	Single	6PS2	(S)-Alprenolol	6PS2-β₂-(S)-Alprenolol
27.27	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
27.27	Single	7BU7	BI167107	7BU7-β₁-BI167107
27.27	Single	7CFM	P395	7CFM-GPBA-P395-Gs/&β;1/&γ;2
27.27	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
27.27	Single	7E32	Serotonin	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
27.27	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
27.27	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
27.27	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
27.27	Single	7SQO	TAK-925	7SQO-OX₂-TAK-925-Gi1/&β;1/&γ;2
27.27	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/&β;1/&γ;2
27.27	Single	7UM5	5-CT	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2
27.27	Single	7UM6	Lisuride	7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2
27.27	Single	7V3Z	PubMed 104895	7V3Z-CB₁-PubMed 104895
27.27	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/&β;1/&γ;2
27.27	Single	7VIF	(S)-FTY720-P	7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2
27.27	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
27.27	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
27.27	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/&β;1/&γ;2
27.27	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/&β;1/&γ;2
27.27	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/&β;1/&γ;2
27.27	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
27.27	Single	8ID4	Linoleic acid	8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2
27.27	Single	8J18	(3R)-3-hydroxydodecanoic acid	8J18-GPR84-(3R)-3-hydroxydodecanoic acid-Gi1/&β;1/&γ;2
27.27	Single	8JLJ	T1AM	8JLJ-TA1-T1AM-chim(NtGi1-Gs)/&β;1/&γ;2
27.27	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
27.27	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
27.27	Single	8UO4	Epinephrine	8UO4-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
27.27	Single	8WC7	ZH8667	8WC7-TA1-ZH8667-chim(NtGi1-Gs)/&β;1/&γ;2
27.27	Single	8X63	Mepyramine	8X63-H₁-Mepyramine
27.27	Single	8X64	Desloratadine	8X64-H₁-Desloratadine
27.27	Consensus	5ht1a_on	Orthosteric Ligand	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2 7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
27.27	Consensus	5ht1d_on	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
27.27	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
27.27	Consensus	a2_off	Orthosteric Ligand	a2a_off
27.27	Consensus	a2a_off	Orthosteric Ligand	8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 5UIG-A_2A-J3.651.884G 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-PubChem 168451710 5K2D-A_2A-ZM241385
27.27	Consensus	amine_on	Orthosteric Ligand	adrenergic_on histamine_on muscarinic_on tar_on 5ht_on dopamine_on
27.27	Consensus	cb1_on_allo	Orthosteric Ligand	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
27.27	Consensus	ffa_on	Orthosteric Ligand	ffa4_on ffa1_on ffa2_on ffa3_on
27.27	Consensus	gi_5ht	Orthosteric Ligand	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2 8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2 7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2 7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2 7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2 7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
27.27	Consensus	go_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
27.27	Consensus	gq_amine	Orthosteric Ligand	gq_muscarinic gq_histamine
27.27	Consensus	histamine_on	Orthosteric Ligand	h1_on h4_on
27.27	Consensus	m2_on_allo	Orthosteric Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
27.27	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
27.27	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491 5ZKP-PAF-Foropafant (SR27417)
27.27	Consensus	prostanoid_off	Orthosteric Ligand	ep_off tp_off dp_off
26.92	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
26.92	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/&β;1/&γ;2
26.92	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
26.92	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
26.92	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2
26.92	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
26.92	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/&β;1/&γ;2
26.92	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
26.92	Consensus	go_vasopressin	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
26.92	Consensus	gs_bombesin	Orthosteric Ligand	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
26.92	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
26.67	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2
26.67	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/&β;1/&γ;2
26.67	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/&β;1/&γ;2
26.67	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
26.47	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/&β;1/&γ;2
26.47	Single	8FLU	Long-acting PTH	8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2
26.32	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
26.32	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
26.32	Single	6OIK	LY2119620	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
26.32	Single	7WC5	Psilocin	7WC5-5-HT_2A-Psilocin
26.32	Single	8GGR	Epinephrine	8GGR-β₂-Epinephrine
26.32	Single	8GGZ	Epinephrine	8GGZ-β₂-Epinephrine
26.32	Single	8IW7	2-Phenylethylamine	8IW7-TAAR9-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
26.32	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2
26.32	Single	8J6Q	Beta-hydroxybutyrate	8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
26.32	Single	8JXT	Histamine	8JXT-H₄-Histamine-PO4-Gi1/&β;1/&γ;2
26.32	Consensus	smo_off_allo	Orthosteric Ligand	6D32-SMO-Cyclopamine-Cyclopamine
26.09	Single	2Y03	Isoprenaline	2Y03-β₁-Isoprenaline
26.09	Single	5TVN	LSD	5TVN-5-HT_2B-LSD
26.09	Single	5WIU	Nemonapride	5WIU-D₄-Nemonapride
26.09	Single	5WIV	Nemonapride	5WIV-D₄-Nemonapride-Na
26.09	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
26.09	Single	5ZK3	Quinuclidinyl benzilate hydrobromide	5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
26.09	Single	6E67	BI167107	6E67-β₂-BI167107-Gs (fused)
26.09	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
26.09	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
26.09	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
26.09	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
26.09	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
26.09	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
26.09	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
26.09	Single	7C4S	S1P	7C4S-S1P₃-S1P
26.09	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
26.09	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2
26.09	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
26.09	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
26.09	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
26.09	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
26.09	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
26.09	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
26.09	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
26.09	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2
26.09	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/&β;1/&γ;2
26.09	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2
26.09	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/&β;1/&γ;2
26.09	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
26.09	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
26.09	Consensus	5ht1_on	Orthosteric Ligand	5ht1a_on 5ht1d_on 5ht1e_on 5ht1f_on 5ht1b_on
26.09	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
26.09	Consensus	beta_on	Orthosteric Ligand	beta1_on beta2_on beta3_on
26.09	Consensus	d4_off	Orthosteric Ligand	5WIU-D₄-Nemonapride
26.09	Consensus	d4_off_allo	Orthosteric Ligand	5WIV-D₄-Nemonapride-Na
26.09	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
26.09	Consensus	gs_muscarinic	Orthosteric Ligand	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
26.09	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
26.09	Consensus	m2_off	Orthosteric Ligand	5ZKB-M₂-AF-DX 384 5ZKC-M₂-N-Methyl Scopolamine 5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
26.09	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.93	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
25.93	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
25.93	Single	7QA8	Peptide	7QA8-STE2-Peptide
25.93	Single	7QA8	Peptide	7QA8-STE2-Peptide
25.93	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2
25.93	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2
25.93	Single	8G59	TUG-891	8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
25.93	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/&β;1/&γ;2
25.93	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/&β;1/&γ;2
25.93	Consensus	class-d_off	Orthosteric Ligand	ste2_off
25.93	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
25.81	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2
25.81	Consensus	glp1_on_allo	Orthosteric Ligand	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
25.71	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/&β;1/&γ;2
25.00	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
25.00	Single	3PBL	Eticlopride	3PBL-D₃-Eticlopride
25.00	Single	3UON	Quinuclidinyl benzilate hydrobromide	3UON-M₂-Quinuclidinyl benzilate hydrobromide
25.00	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
25.00	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
25.00	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
25.00	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
25.00	Single	5TE5	20-Methanoretinal	5TE5-Rhodopsin-20-Methanoretinal
25.00	Single	5V56	TC114	5V56-SMO-TC114
25.00	Single	5V57	TC114	5V57-SMO-TC114
25.00	Single	5XR8	AM841	5XR8-CB₁-AM841
25.00	Single	5XRA	AM11542	5XRA-CB₁-AM11542
25.00	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
25.00	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
25.00	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
25.00	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
25.00	Single	6QNO	All-trans-retinal	6QNO-Rhodopsin-All-trans-retinal-Gi1/&β;1/&γ;1
25.00	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
25.00	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
25.00	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
25.00	Single	7DFL	Histamine	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
25.00	Single	7E2Y	Serotonin	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
25.00	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
25.00	Single	7FEE	PubMed 104895	7FEE-CB₁-PubMed 104895-ZCZ011
25.00	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
25.00	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/&β;1/&γ;2
25.00	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2
25.00	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2
25.00	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/&β;1/&γ;2
25.00	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
25.00	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2
25.00	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
25.00	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2
25.00	Single	7XTB	Serotonin	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2
25.00	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2
25.00	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Single	7YS6	Serotonin	7YS6-5-HT₆-Serotonin-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
25.00	Single	8DPF	Lorcaserin	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.00	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2
25.00	Single	8GGS	Epinephrine	8GGS-β₂-Epinephrine
25.00	Single	8GGY	Epinephrine	8GGY-β₂-Epinephrine
25.00	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/&β;1/&γ;2
25.00	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/&β;1/&γ;2
25.00	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2
25.00	Single	8ITF	DMCHA	8ITF-TAAR9-DMCHA-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Single	8JD0	J9R	8JD0-mGlu2; mGlu3-Glutamate-J9R
25.00	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2
25.00	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/&β;1/&γ;2
25.00	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab-Cholesterol
25.00	Single	8UNV	Epinephrine	8UNV-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
25.00	Single	8UNX	Epinephrine	8UNX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
25.00	Single	8W8B	SEP-363856	8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
25.00	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
25.00	Consensus	5ht4_on	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
25.00	Consensus	5ht5_off	Orthosteric Ligand	5ht5a_off
25.00	Consensus	d3_off	Orthosteric Ligand	3PBL-D₃-Eticlopride
25.00	Consensus	gq_histamine	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
25.00	Consensus	gs_vip-pacap	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
25.00	Consensus	h1_on	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
25.00	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
25.00	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
25.00	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
25.00	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
25.00	Consensus	ox1_off_allo	Orthosteric Ligand	6TOD-OX₁-EMPA-Na 6TOS-OX₁-GSK1059865-Na 6TQ4-OX₁-PubChem 16046844-Na 6TO7-OX₁-Suvorexant-Na
25.00	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
25.00	Consensus	sst4_on	Orthosteric Ligand	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
25.00	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
24.32	Consensus	gs_class-b	Orthosteric Ligand	gs_class-b1 gs_class-b2
24.32	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
24.24	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2
24.24	Single	6NBH	Long-acting PTH analog	6NBH-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
24.24	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
24.24	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/&β;1/&γ;2
24.24	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/&β;1/&γ;2
24.14	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
24.14	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
24.14	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
24.00	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
24.00	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
24.00	Single	6H7N	(S)-Xamoterol	6H7N-β₁-(S)-Xamoterol
24.00	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/&β;1/&γ;2
24.00	Single	6KQI	PubMed 104895	6KQI-CB₁-PubMed 104895-ORG27569
24.00	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
24.00	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2
24.00	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
24.00	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
24.00	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
24.00	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2
24.00	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
24.00	Single	8JPB	Neurotensin 8-13	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
24.00	Single	8JWY	PubChem 168451710	8JWY-A_2A-PubChem 168451710
24.00	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
24.00	Consensus	adgrg_on	Orthosteric Ligand	adgrg2_on adgrg3_on
24.00	Consensus	beta1_on	Orthosteric Ligand	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
24.00	Consensus	blt1_off	Orthosteric Ligand	7K15-BLT₁-MKD046-Na
24.00	Consensus	blt_off	Orthosteric Ligand	blt1_off
24.00	Consensus	cb1_off_allo	Orthosteric Ligand	6KQI-CB₁-PubMed 104895-ORG27569
24.00	Consensus	class-b2_on	Orthosteric Ligand	adgrg_on
24.00	Consensus	gi_prostanoid	Orthosteric Ligand	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2 8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
24.00	Consensus	gpr119_on	Orthosteric Ligand	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2 7WCN-GPR119-AR231453-Gs/&β;1/&γ;2 7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2 7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
24.00	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
24.00	Consensus	nts1_on	Orthosteric Ligand	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
24.00	Consensus	nts_on	Orthosteric Ligand	nts1_on
23.81	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
23.81	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
23.81	Single	3PWH	ZM241385	3PWH-A_2A-ZM241385
23.81	Single	3VG9	ZM241385	3VG9-A_2A-ZM241385-Antibody
23.81	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
23.81	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
23.81	Single	6KUX	RS-79948	6KUX-α_2a-RS-79948
23.81	Single	6NWE	Octyl Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
23.81	Single	6OBA	(S)-Alprenolol	6OBA-β₂-(S)-Alprenolol-GTPL11074
23.81	Single	7DHR	Isoprenaline	7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2
23.81	Single	7LJD	Dopamine	7LJD-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;1
23.81	Single	7SRS	LSD	7SRS-5-HT_2B-LSD-Arrestin2
23.81	Single	7TUZ	7alpha,25-dihydroxycholesterol	7TUZ-GPR183-7alpha,25-dihydroxycholesterol-Gi1/&β;1/&γ;2
23.81	Single	7X2F	Dopamine	7X2F-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
23.81	Single	7X5H	5-CT	7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2
23.81	Single	7XRR	Lemborexant	7XRR-OX₂-Lemborexant
23.81	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
23.81	Single	8FN0	Neurotensin/neuromedin N	8FN0-NTS₁-Neurotensin/neuromedin N-PubChem 118610427-chim(NtGi1-Go)/&β;1/&γ;2
23.81	Single	8GEA	Epinephrine	8GEA-β₂-Epinephrine-Gs/&β;1/&γ;2
23.81	Single	8GED	Epinephrine	8GED-β₂-Epinephrine-Gs/&β;1/&γ;2
23.81	Single	8GG7	Epinephrine	8GG7-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
23.81	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
23.81	Single	8UNL	Epinephrine	8UNL-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
23.81	Single	8UNO	Epinephrine	8UNO-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
23.81	Single	8UNT	Epinephrine	8UNT-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
23.81	Single	8UNU	Epinephrine	8UNU-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
23.81	Single	8UO1	Epinephrine	8UO1-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
23.81	Consensus	5ht_on	Orthosteric Ligand	5ht1_on 5ht2_on 5ht4_on 5ht5_on 5ht6_on 5ht7_on
23.81	Consensus	a2a_off_allo	Orthosteric Ligand	6ZDR-A_2A-HMS1413f12-Na 6GT3-A_2A-Imaradenant-Na 8CU7-A_2A-LJ-4517-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PubChem 92460631; psb36-Na 5MZJ-A_2A-Theophylline-Na 5OLO-A_2A-Tozadenant-Na 5OLH-A_2A-Vipadenant-Na 5NM4-A_2A-ZM241385-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5MZP-A_2A-Caffeine-Na 8CIC-A_2A-Etrumadenant-Na
23.81	Consensus	alpha2a_off	Orthosteric Ligand	6KUX-α_2a-RS-79948
23.81	Consensus	beta2_off_allo	Orthosteric Ligand	6OBA-β₂-(S)-Alprenolol-GTPL11074
23.81	Consensus	gs_5ht	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2 7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2 7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
23.81	Consensus	mglu_on	Other Ligand	mglu2_on mglu4_on
23.53	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/&β;1/&γ;2
23.53	Single	8WCC	Cyclohexylammonium ion	8WCC-TA1-Cyclohexylammonium ion
23.33	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
23.33	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/&β;1/&γ;2
23.33	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
23.33	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
23.33	Consensus	go_class-b	Orthosteric Ligand	go_class-b1 go_class-b2
23.33	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
23.08	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
23.08	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
23.08	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/&β;1/&γ;2
23.08	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2
23.08	Single	8GAG	YVF	8GAG-CB₁-YVF-Gi1/&β;1/&γ;2
23.08	Single	8XJO	U46619	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
23.08	Consensus	5ht5a_off	Orthosteric Ligand	7UM4-5-HT_5A-AS2674723
23.08	Consensus	ep4_on	Orthosteric Ligand	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2
23.08	Consensus	fpa_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
23.08	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
23.08	Consensus	gs_galanin	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
23.08	Consensus	gs_lipid	Orthosteric Ligand	gs_ffa gs_prostanoid
23.08	Consensus	gs_prostanoid	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2 7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
23.08	Consensus	gs_pth	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7F16-PTH2-TIP39-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
22.86	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/&β;1/&γ;1
22.86	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
22.73	Single	3REY	PubChem 5697	3REY-A_2A-PubChem 5697
22.73	Single	3RZE	Cidoxepin	3RZE-H₁-Cidoxepin
22.73	Single	4MQT	Iperoxo	4MQT-M₂-Iperoxo-LY2119620
22.73	Single	5TE3	Octyl Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl Beta-D-Glucopyranoside
22.73	Single	6AQF	ZM241385	6AQF-A_2A-ZM241385
22.73	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
22.73	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
22.73	Single	6TPN	HTL6641	6TPN-OX₂-HTL6641
22.73	Single	6WH4	Methiothepin	6WH4-5-HT_2A-Methiothepin
22.73	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
22.73	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
22.73	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
22.73	Single	6ZDV	PubChem 984073	6ZDV-A_2A-PubChem 984073-Na
22.73	Single	6ZG9	GSK1034702	6ZG9-M₁-GSK1034702
22.73	Single	7EJ8	Brimonidine	7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2
22.73	Single	7EJA	Dexmedetomidine	7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
22.73	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
22.73	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/&β;1/&γ;2
22.73	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
22.73	Single	8DPG	Psilocin	8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
22.73	Single	8GGL	Epinephrine	8GGL-β₂-Epinephrine
22.73	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2
22.73	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
22.73	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/&β;1/&γ;2
22.73	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
22.73	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
22.73	Consensus	cb1_off	Orthosteric Ligand	5TGZ-CB₁-AM6538 5U09-CB₁-Taranabant
22.73	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
22.73	Consensus	gi_class-f	Orthosteric Ligand	gi_frizzled
22.73	Consensus	gi_frizzled	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
22.73	Consensus	m1_off_allo	Orthosteric Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
22.73	Consensus	sensory_off	Orthosteric Ligand	opsin_off
22.58	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
22.58	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
22.58	Consensus	vpac1_on	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
22.50	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on calcitonin_on vip-pacap_on pth_on crf_on
22.22	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
22.22	Single	5MZJ	Theophylline	5MZJ-A_2A-Theophylline-Na
22.22	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
22.22	Single	7WC4	Serotonin	7WC4-5-HT_2A-Serotonin
22.22	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/&β;1/&γ;2
22.22	Single	8GEJ	Epinephrine	8GEJ-β₂-Epinephrine-Gs/&β;1/&γ;2
22.22	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
22.22	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/&β;1/&γ;2
22.22	Single	8PWN	Theophylline	8PWN-A_2A-Theophylline
22.22	Single	8SAI	1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine	8SAI-GPR34-1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-Gi1/&β;1/&γ;2
22.22	Consensus	class-d_off	Orthosteric Ligand	ste2_off
22.22	Consensus	pth1_on	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2
22.22	Consensus	vip-pacap_on	Orthosteric Ligand	vpac1_on vpac2_on pca1_on
21.88	Single	6NBF	Long-acting PTH analog	6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
21.88	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/&β;1/&γ;2
21.88	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
21.88	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2
21.88	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
21.88	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/&β;1/&γ;2
21.88	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
21.88	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
21.74	Single	2Y01	Dobutamine	2Y01-β₁-Dobutamine
21.74	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
21.74	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
21.74	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
21.74	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
21.74	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
21.74	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
21.74	Single	5UIG	J3.651.884G	5UIG-A_2A-J3.651.884G
21.74	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
21.74	Single	6GPS	MK0812	6GPS-CCR2-MK0812
21.74	Single	6IIV	Daltroban	6IIV-TP-Daltroban
21.74	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2
21.74	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
21.74	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
21.74	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
21.74	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
21.74	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
21.74	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
21.74	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
21.74	Single	7WC7	Lisuride	7WC7-5-HT_2A-Lisuride
21.74	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
21.74	Single	7XJH	Isoproterenol	7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
21.74	Single	7XTC	5-CT	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
21.74	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2
21.74	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
21.74	Consensus	5ht7_on	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
21.74	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
21.74	Consensus	blt_on	Orthosteric Ligand	blt1_on
21.74	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
21.74	Consensus	leuko_on	Orthosteric Ligand	blt_on
21.74	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
21.74	Consensus	m4_on_allo	Orthosteric Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
21.74	Consensus	p2y12_off	Orthosteric Ligand	4NTJ-P2Y₁₂-AZD1283 7PP1-P2Y₁₂-Selatogrel
21.74	Consensus	tachykinin_off	Orthosteric Ligand	nk1_off
21.74	Consensus	tp_off	Orthosteric Ligand	6IIV-TP-Daltroban 6IIU-TP-Ramatroban
21.62	Consensus	gs_glucagon	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 6WZG-Secretin-Secretin-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2 7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2 7DTY-GIP-GIP-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
21.43	Consensus	gs_class-b1	Orthosteric Ligand	gs_glucagon gs_vip-pacap gs_pth gs_calcitonin gs_crf
21.21	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/&β;1/&γ;2
21.21	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
21.21	Consensus	go_class-b1	Orthosteric Ligand	go_crf
21.21	Consensus	go_crf	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
21.21	Consensus	gs_cgrp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
21.05	Single	3RFM	Caffeine	3RFM-A_2A-Caffeine
21.05	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
21.05	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
20.83	Single	2Y00	Dobutamine	2Y00-β₁-Dobutamine
20.83	Single	4JKV	Taladegib (LY2940680)	4JKV-SMO-Taladegib (LY2940680)
20.83	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
20.83	Single	5CGC	HTL14242	5CGC-mGlu₅-HTL14242
20.83	Single	5XPR	Bosentan	5XPR-ET_B-Bosentan
20.83	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
20.83	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
20.83	Single	6GPX	MK0812	6GPX-CCR2-MK0812
20.83	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
20.83	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
20.83	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
20.83	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
20.83	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
20.83	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
20.83	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
20.83	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2
20.83	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
20.83	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
20.83	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/&β;1/&γ;2
20.83	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
20.83	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
20.83	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
20.83	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
20.83	Consensus	ep3_on	Orthosteric Ligand	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
20.83	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
20.83	Consensus	ep_off	Orthosteric Ligand	ep4_off
20.83	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
20.69	Consensus	sst_off	Orthosteric Ligand	sst2_off
20.59	Single	6LML	Glucagon	6LML-Glucagon-Glucagon
20.59	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
20.59	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
20.59	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/&β;1/&γ;2
20.59	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
20.59	Consensus	glp1_on	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2 6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2 7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2 8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
20.59	Consensus	secretin_on	Orthosteric Ligand	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
20.00	Single	3C9M	11-cis-Retinal	3C9M-Rhodopsin-11-cis-Retinal
20.00	Single	3OE8	IT1t	3OE8-CXCR4-IT1t
20.00	Single	3PDS	Hydroxybenzylisoproterenol	3PDS-β₂-Hydroxybenzylisoproterenol
20.00	Single	3UZA	GTPL9236	3UZA-A_2A-GTPL9236
20.00	Single	5TZR	-	5TZR-FFA1 (GPR40)-MK8666
20.00	Single	5V54	Methiothepin	5V54-5-HT_1B-Methiothepin
20.00	Single	5WKT	Octyl Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
20.00	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
20.00	Single	6E59	L-760735	6E59-NK₁-L-760735
20.00	Single	6FUF	All-trans-retinal	6FUF-Rhodopsin-All-trans-retinal-Go/&β;1/&γ;2
20.00	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
20.00	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
20.00	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
20.00	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2
20.00	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
20.00	Single	7MT8	All-trans-retinal	7MT8-Rhodopsin-All-trans-retinal-GRK1
20.00	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
20.00	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
20.00	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2
20.00	Single	7W41	PD176252	7W41-BB₂-PD176252
20.00	Single	8DPI	Lorcaserin	8DPI-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.00	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2
20.00	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2
20.00	Single	8J21	Butyric acid	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
20.00	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/&β;1/&γ;2
20.00	Single	8POK	Histamine	8POK-H₂-Histamine-Gs/&β;1/&γ;2
20.00	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
20.00	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.00	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/&β;1/&γ;2
20.00	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
20.00	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
20.00	Consensus	5ht1_off	Orthosteric Ligand	5ht1b_off
20.00	Consensus	5ht1b_off	Orthosteric Ligand	5V54-5-HT_1B-Methiothepin
20.00	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
20.00	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
20.00	Consensus	ffa3_on	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
20.00	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-Methyl Scopolamine 5ZHP-M₃-PubChem 134828589
20.00	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
20.00	Consensus	nk1_off	Orthosteric Ligand	6J20-NK₁-Aprepitant 6HLL-NK₁-CP99994 6E59-NK₁-L-760735
20.00	Consensus	nts1_on_allo	Orthosteric Ligand	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
19.44	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
19.44	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2
19.35	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
19.35	Consensus	pca1_on	Orthosteric Ligand	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
19.23	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
19.23	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
19.23	Single	6IIU	Ramatroban	6IIU-TP-Ramatroban
19.23	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
19.23	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2
19.23	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
19.23	Consensus	ep_on	Orthosteric Ligand	ep4_on ep2_on ep3_on
19.23	Consensus	prostanoid_on	Orthosteric Ligand	ep_on fpa_on
19.05	Single	1L9H	11-cis-Retinal	1L9H-Rhodopsin-11-cis-Retinal
19.05	Single	1U19	11-cis-Retinal	1U19-Rhodopsin-11-cis-Retinal
19.05	Single	2G87	All-trans-retinal	2G87-Rhodopsin-All-trans-retinal
19.05	Single	2I35	11-cis-Retinal	2I35-Rhodopsin-11-cis-Retinal
19.05	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
19.05	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
19.05	Single	6HLL	CP99994	6HLL-NK₁-CP99994
19.05	Single	6I9K	9-cis-Retinal	6I9K-Rhodopsin-9-cis-Retinal
19.05	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
19.05	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
19.05	Single	7V68	Iperoxo	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
19.05	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
19.05	Single	7XP6	Strychnine	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
19.05	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
19.05	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
19.05	Consensus	class-t_on	Orthosteric Ligand	taste2_on
19.05	Consensus	go_adhesion	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
19.05	Consensus	go_class-b2	Orthosteric Ligand	go_adhesion
19.05	Consensus	gs_class-t	Orthosteric Ligand	gs_taste
19.05	Consensus	gs_taste	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
19.05	Consensus	mt2_on	Orthosteric Ligand	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
19.05	Consensus	smo_on_allo	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
19.05	Consensus	taste2_on	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
18.92	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2
18.75	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
18.75	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/&β;1/&γ;2
18.75	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2
18.52	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
18.52	Single	5CGD	HTL14242	5CGD-mGlu₅-HTL14242
18.52	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1 (GPR40)-MK8666; PubChem 127053597
18.52	Single	6K1Q	IRL2500	6K1Q-ET_B-IRL2500
18.52	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
18.52	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
18.52	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
18.52	Consensus	ffa4_on_allo	Orthosteric Ligand	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
18.42	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
18.18	Single	1GZM	11-cis-Retinal	1GZM-Rhodopsin-11-cis-Retinal
18.18	Single	2PED	9-cis-Retinal	2PED-Rhodopsin-9-cis-Retinal
18.18	Single	3C9L	11-cis-Retinal	3C9L-Rhodopsin-11-cis-Retinal
18.18	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
18.18	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
18.18	Single	5U09	Taranabant	5U09-CB₁-Taranabant
18.18	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
18.18	Single	6NBI	Long-acting PTH analog	6NBI-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
18.18	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
18.18	Single	6OYA	All-trans-retinal	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
18.18	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
18.18	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
18.18	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/&β;1/&γ;2
18.18	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
18.18	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
18.18	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
18.18	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
18.18	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2
18.18	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
18.18	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
18.18	Single	8A6C	All-trans-retinal	8A6C-Rhodopsin-All-trans-retinal
18.18	Single	8A6D	All-trans-retinal	8A6D-Rhodopsin-All-trans-retinal
18.18	Single	8A6E	All-trans-retinal	8A6E-Rhodopsin-All-trans-retinal
18.18	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
18.18	Single	8HMP	PubChem 69921479	8HMP-GPR52-PubChem 69921479-Gs/&β;1/&γ;2
18.18	Single	8J20	Valeric acid	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
18.18	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
18.18	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
18.18	Consensus	5ht2c_on	Orthosteric Ligand	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
18.18	Consensus	class-d_on	Orthosteric Ligand	ste2_on
18.18	Consensus	class-f_off	Orthosteric Ligand	smo_off
18.18	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
18.18	Consensus	ffa3_on_allo	Orthosteric Ligand	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
18.18	Consensus	gt_class-a	Orthosteric Ligand	gt_opsin
18.18	Consensus	gt_opsin	Orthosteric Ligand	gt_sensory
18.18	Consensus	gt_sensory	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
18.18	Consensus	melatonin_on	Orthosteric Ligand	mt1_on mt2_on
18.18	Consensus	opsin_off	Orthosteric Ligand	1U19-Rhodopsin-11-cis-Retinal 2PED-Rhodopsin-9-cis-Retinal 5TE5-Rhodopsin-20-Methanoretinal
17.86	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
17.86	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
17.86	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.86	Consensus	gs_adgr	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
17.86	Consensus	gs_class-b2	Orthosteric Ligand	gs_adgr
17.65	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
17.65	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
17.65	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
17.65	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
17.65	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
17.39	Single	3OAX	11-cis-Retinal	3OAX-Rhodopsin-11-cis-Retinal
17.39	Single	6A94	Zotepine	6A94-5-HT_2A-Zotepine
17.39	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
17.39	Single	6TPK	Retosiban	6TPK-OT-Retosiban
17.39	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
17.39	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
17.39	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
17.39	Single	7ZBC	11-cis-Retinal	7ZBC-Rhodopsin-11-cis-Retinal
17.39	Single	8FCZ	11-cis-Retinal	8FCZ-Rhodopsin-11-cis-Retinal
17.39	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
17.39	Single	8HQN	9(S)-HODE	8HQN-GPR132-9(S)-HODE-Gi1/&β;1/&γ;2
17.39	Single	8JSP	Ulotaront	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2
17.39	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
17.39	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
17.39	Consensus	gi_melatonin	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2 7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
17.39	Consensus	ot_off	Orthosteric Ligand	6TPK-OT-Retosiban
17.39	Consensus	vasopressin-ot_off	Orthosteric Ligand	ot_off
17.24	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/&β;1/&γ;2
17.24	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
17.14	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/&β;1/&γ;2
17.14	Consensus	crf1_on	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
17.14	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
17.07	Consensus	glucagon_on	Orthosteric Ligand	gip_on glu_on secretin_on ghrh_on glp_on
16.67	Single	1HZX	11-cis-Retinal	1HZX-Rhodopsin-11-cis-Retinal
16.67	Single	5MZP	Caffeine	5MZP-A_2A-Caffeine-Na
16.67	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
16.67	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
16.67	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
16.67	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
16.67	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
16.67	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/&β;1/&γ;2
16.67	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
16.67	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
16.67	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
16.67	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
16.67	Single	7VH0	Ramelteon	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
16.67	Single	8EJC	TAK-875	8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
16.67	Single	8IOC	Gamma-MSH	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
16.67	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/&β;1/&γ;2
16.67	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
16.67	Single	8WCB	Cyclohexylammonium ion	8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.67	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-alpha-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
16.67	Consensus	gip_on	Orthosteric Ligand	7DTY-GIP-GIP-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
16.67	Consensus	gip_on_allo	Orthosteric Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
16.67	Consensus	gs_crf	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
16.67	Consensus	hcar_off	Orthosteric Ligand	succinate_off
16.67	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
16.13	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/&β;1/&γ;2
16.13	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
16.00	Single	4PHU	Fasiglifam	4PHU-FFA1 (GPR40)-Fasiglifam
16.00	Single	4WW3	All-trans-retinal	4WW3-Rhodopsin-All-trans-retinal
16.00	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
16.00	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
16.00	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
16.00	Consensus	ccr2_off_allo	Other Ligand	5T1A-CCR2-PubChem 68764898; PubChem 12093170 6GPX-CCR2-MK0812
15.79	Single	3PXO	All-trans-retinal	3PXO-Rhodopsin-All-trans-retinal
15.79	Single	5DYS	All-trans-retinal	5DYS-Rhodopsin-All-trans-retinal
15.79	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2
15.79	Single	7XKE	Betahydroxyandrosterone	7XKE-ADGRG2-Betahydroxyandrosterone-chim(NtGi1-Gs)/&β;1/&γ;2
15.79	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2
15.79	Consensus	gabab_off	Other Ligand	7C7S-GABA_B1, GABA_B2-CGP54626 7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid 6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
15.62	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
15.62	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
15.62	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2
15.62	Consensus	class-d_on	Orthosteric Ligand	ste2_on
15.62	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
15.62	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
15.38	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
15.38	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
15.38	Single	7EPE	NAM563	7EPE-mGlu-NAM563
15.38	Single	7P2L	4YI	7P2L-mGlu₅-4YI
15.38	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
15.38	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
15.38	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
15.38	Consensus	s1p2_on	Orthosteric Ligand	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
15.15	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/&β;1/&γ;2
15.15	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
15.00	Single	2HPY	All-trans-retinal	2HPY-Rhodopsin-All-trans-retinal
15.00	Single	6OY9	All-trans-retinal	6OY9-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
15.00	Single	6TQ9	SB-408124	6TQ9-OX₁-SB-408124
15.00	Single	7MTB	All-trans-retinal	7MTB-Rhodopsin-All-trans-retinal-GRK1
15.00	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
15.00	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Cholesterol-Gi1/&β;1/&γ;2
15.00	Consensus	sensory_on	Orthosteric Ligand	opsin_on
14.81	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
14.81	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
14.81	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
14.81	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
14.81	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1
14.81	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
14.81	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/&β;1/&γ;2
14.81	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
14.81	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
14.81	Consensus	nts1_off	Orthosteric Ligand	6Z4Q-NTS₁-SR142948A 6Z4S-NTS₁-SR48692
14.81	Consensus	nts_off	Orthosteric Ligand	nts1_off
14.71	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/&β;1/&γ;2
14.63	Consensus	ct_on	Orthosteric Ligand	7TYL-CT-Amylin-Gs/&β;1/&γ;2 7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
14.29	Single	3PQR	All-trans-retinal	3PQR-Rhodopsin-All-trans-retinal-Gt(CT)
14.29	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
14.29	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
14.29	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
14.29	Single	6LI0	GTPL9804	6LI0-GPR52-GTPL9804
14.29	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/&β;1/&γ;2
14.29	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
14.29	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
14.29	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/&β;1/&γ;2; RAMP3
14.29	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2
14.29	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2
14.29	Single	7MT9	All-trans-retinal	7MT9-Rhodopsin-All-trans-retinal-GRK1
14.29	Single	7MTA	All-trans-retinal	7MTA-Rhodopsin-All-trans-retinal-GRK1
14.29	Single	8EIT	Doconexent	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
14.29	Single	8IU2	Retinal	8IU2-Opsin1LW-Retinal-Gi1/&β;1/&γ;2
14.29	Consensus	adgrg2_on	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
14.29	Consensus	cyslt2_off	Orthosteric Ligand	6RZ6-CysLT₂-ONO-2570366 6RZ9-CysLT₂-ONO-2770372 6RZ8-CysLT₂-ONO-2080365
14.29	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off
14.29	Consensus	ep2_on	Orthosteric Ligand	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
14.29	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
14.29	Consensus	opsin_on	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
13.89	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
13.89	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP3
13.79	Single	8INR	Alpha-MSH	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
13.64	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
13.64	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
13.64	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
13.64	Single	6TP4	ACT-462206	6TP4-OX₁-ACT-462206
13.64	Single	6TQ4	PubChem 16046844	6TQ4-OX₁-PubChem 16046844-Na
13.64	Single	7UL2	SR48692	7UL2-NTS₁-SR48692-Na
13.64	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
13.64	Consensus	gs_calcitonin	Orthosteric Ligand	gs_ct gs_cgrp
13.64	Consensus	mt1_on	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
13.64	Consensus	nts1_off_allo	Orthosteric Ligand	7UL2-NTS₁-SR48692-Na
13.51	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
13.33	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
13.33	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
13.33	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2
13.04	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
13.04	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
13.04	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
13.04	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
13.04	Single	6TQ6	PubChem 145714283	6TQ6-OX₁-PubChem 145714283
13.04	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
13.04	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
13.04	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
13.04	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
13.04	Consensus	smo_on_allo	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
12.90	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
12.90	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
12.50	Single	6FFI	MMPEP	6FFI-mGlu₅-MMPEP
12.50	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
12.50	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
12.50	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2
12.50	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
12.50	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/&β;1/&γ;2
12.50	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2
12.50	Single	8T3V	DHA	8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
12.50	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
12.50	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/&β;1/&γ;2
12.12	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
12.00	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
12.00	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2
12.00	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
12.00	Single	8EJK	TAK-875	8EJK-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
12.00	Consensus	ffa1_on	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
11.54	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
11.54	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
11.43	Consensus	ghrh_on	Orthosteric Ligand	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
11.36	Consensus	glu_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2 6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2 8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2 8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2 7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2 6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
11.11	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2
11.11	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
11.11	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
11.11	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/&β;1/&γ;2
11.11	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
11.11	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
11.11	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
10.81	Consensus	calcitonin_on	Orthosteric Ligand	ct_on ctlike_on
10.71	Single	8DWC	Proenkephalin-A	8DWC-MRGPRX1-Proenkephalin-A-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
10.71	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
10.71	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
10.53	Single	4A4M	All-trans-retinal	4A4M-Rhodopsin-All-trans-retinal-Gt(CT)
10.53	Single	5EN0	All-trans-retinal	5EN0-Rhodopsin-All-trans-retinal-Gt(CT)
10.34	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/&β;1/&γ;2
10.00	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/&β;1/&γ;2
10.00	Consensus	class-c_on	Other Ligand	gabab_on mglu_on
9.68	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2
9.68	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2
9.52	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
9.52	Single	7VDM	Substance P	7VDM-MRGPRX2-Substance P-Gi1/&β;1/&γ;2
9.52	Single	7XKD	Betahydroxyandrosterone	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
9.52	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/&β;1/&γ;2
9.38	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/&β;1/&γ;2
9.09	Single	2ZIY	11-cis-Retinal	2ZIY-Rhodopsin-11-cis-Retinal
9.09	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
9.09	Single	7S8O	(R)-Zinc-3573	7S8O-MRGPRX2-(R)-Zinc-3573-Gi1/&β;1/&γ;2
9.09	Single	8F76	-	8F76-OR51E2-Gs/&β;1/&γ;2
9.09	Single	8JGB	Conorfamide-Tx2	8JGB-MRGPRX1-Conorfamide-Tx2-Gi1/&β;1/&γ;2
9.09	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
9.09	Consensus	adgrg3_on	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
8.70	Single	3AYM	All-trans-retinal	3AYM-Rhodopsin-All-trans-retinal
8.70	Single	7S8N	(R)-Zinc-3573	7S8N-MRGPRX2-(R)-Zinc-3573-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8.33	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
8.33	Single	8DWH	Compound-16	8DWH-MRGPRX1-Compound-16-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8.33	Single	8U8F	PML	8U8F-GPR3-PML-Gs/&β;1/&γ;2
8.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
8.00	Single	7ZBE	11-cis-Retinal	7ZBE-Rhodopsin-11-cis-Retinal
7.69	Single	6ORV	TT-OAD2	6ORV-GLP-1-TT-OAD2-Gs/&β;1/&γ;2
7.69	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/&β;1/&γ;2
7.14	Consensus	mglu2_on	Other Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
6.90	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2
6.38	Consensus	gs_ct	Orthosteric Ligand	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 7TYL-CT-Amylin-Gs/&β;1/&γ;2 8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
6.06	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
5.88	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
5.88	Single	6D35	Cholesterol	6D35-SMO-Cholesterol
5.88	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
5.88	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
5.88	Single	6UO8	SKF97541	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
5.88	Single	6UO9	SKF97541	6UO9-GABA_B1, GABA_B2-SKF97541
5.88	Single	6W2X	PubChem 5311042	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
5.88	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
5.88	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
5.88	Single	7C7Q	Baclofen	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
5.88	Single	7C7S	CGP54626	7C7S-GABA_B1, GABA_B2-CGP54626
5.88	Single	7CUM	CGP54626	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
5.88	Single	7DD5	Ca3	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
5.88	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
5.88	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
5.88	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
5.88	Single	7DGE	Quisqualate	7DGE-mGlu1; mGlu1-Quisqualate
5.88	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
5.88	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
5.88	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
5.88	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
5.88	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
5.88	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
5.88	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
5.88	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
5.88	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.88	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.88	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.88	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.88	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
5.88	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
5.88	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
5.88	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
5.88	Single	7EB2	Baclofen	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
5.88	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
5.88	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
5.88	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
5.88	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
5.88	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
5.88	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
5.88	Single	7FIH	hCG	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
5.88	Single	7FII	hCG	7FII-LH-hCG-6fuf
5.88	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
5.88	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
5.88	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
5.88	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
5.88	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
5.88	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
5.88	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
5.88	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
5.88	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
5.88	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
5.88	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
5.88	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
5.88	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
5.88	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
5.88	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
5.88	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
5.88	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
5.88	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
5.88	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.88	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.88	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.88	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.88	Single	7T9N	M22 Fab	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
5.88	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
5.88	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
5.88	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
5.88	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
5.88	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
5.88	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
5.88	Single	7XW6	M22 Fab	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
5.88	Single	7XW7	K1-70	7XW7-TSH-K1-70
5.88	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
5.88	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
5.88	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
5.88	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
5.88	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
5.88	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
5.88	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
5.88	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
5.88	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
5.88	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
5.88	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
5.88	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
5.88	Single	8JD0	Glutamate	8JD0-mGlu2; mGlu3-Glutamate-J9R
5.88	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
5.88	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
5.88	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
5.88	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
5.88	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
5.88	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
5.88	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
5.88	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
5.88	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
5.88	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
5.88	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
5.88	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
5.88	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
5.88	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
5.88	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
5.88	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
5.88	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
5.88	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
5.88	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
5.88	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
5.88	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
5.88	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
5.88	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
5.88	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
5.88	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
5.88	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
5.88	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
5.88	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
5.88	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
5.88	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
5.88	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
5.88	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.88	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.88	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.88	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.88	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
5.88	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
5.88	Consensus	class-c_off	Orthosteric Ligand	gabab_off mglu_off
5.88	Consensus	class-c_off	Orthosteric Ligand	gabab_off mglu_off
5.88	Consensus	class-c_off	Other Ligand	gabab_off mglu_off
5.88	Consensus	class-c_on	Orthosteric Ligand	gabab_on mglu_on
5.88	Consensus	class-c_on	Orthosteric Ligand	gabab_on mglu_on
5.88	Consensus	fsh_on_allo	Orthosteric Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
5.88	Consensus	gabab_off	Orthosteric Ligand	7C7S-GABA_B1, GABA_B2-CGP54626 7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid 6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
5.88	Consensus	gabab_on	Orthosteric Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
5.88	Consensus	gi_class-c	Orthosteric Ligand	gi_mglu gi_gaba
5.88	Consensus	gi_class-c	Orthosteric Ligand	gi_mglu gi_gaba
5.88	Consensus	gi_gaba	Orthosteric Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
5.88	Consensus	gi_mglu	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
5.88	Consensus	gi_mglu	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
5.88	Consensus	gphr_on	Orthosteric Ligand	lh_on tsh_on
5.88	Consensus	gs_gphr	Orthosteric Ligand	7T9I-TSH-TSH-Gs/&β;1/&γ;2 7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
5.88	Consensus	gs_protein	Orthosteric Ligand	gs_gphr
5.88	Consensus	lh_on	Orthosteric Ligand	7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
5.88	Consensus	lh_on_allo	Orthosteric Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
5.88	Consensus	mglu2_off	Orthosteric Ligand	7MTQ-mGlu2; mGlu2-LY341495
5.88	Consensus	mglu2_off	Orthosteric Ligand	7MTQ-mGlu2; mGlu2-LY341495
5.88	Consensus	mglu2_on	Orthosteric Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
5.88	Consensus	mglu2_on	Orthosteric Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
5.88	Consensus	mglu3_off	Orthosteric Ligand	7WI8-mGlu3; mGlu3-LY341495 7WIH-mGlu3; mGlu3-LY2794193
5.88	Consensus	mglu3_off	Orthosteric Ligand	7WI8-mGlu3; mGlu3-LY341495 7WIH-mGlu3; mGlu3-LY2794193
5.88	Consensus	mglu4_on	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
5.88	Consensus	mglu4_on	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
5.88	Consensus	mglu5_off	Orthosteric Ligand	7FD9-mGlu5; mGlu5-LY341495
5.88	Consensus	mglu5_off	Orthosteric Ligand	7FD9-mGlu5; mGlu5-LY341495
5.88	Consensus	mglu_off	Orthosteric Ligand	mglu2_off mglu3_off mglu5_off
5.88	Consensus	mglu_off	Orthosteric Ligand	mglu2_off mglu3_off mglu5_off
5.88	Consensus	mglu_on	Orthosteric Ligand	mglu2_on mglu4_on
5.88	Consensus	mglu_on	Orthosteric Ligand	mglu2_on mglu4_on
5.88	Consensus	smo_off_allo	Other Ligand	6D32-SMO-Cyclopamine-Cyclopamine
5.88	Consensus	tsh_on	Orthosteric Ligand	7T9I-TSH-TSH-Gs/&β;1/&γ;2
5.88	Consensus	tsh_on_allo	Orthosteric Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
5.56	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
5.56	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
5.56	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
5.56	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
5.56	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
5.56	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
5.56	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
5.56	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
5.56	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
5.56	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
5.26	Single	7KNU	Calcitonin gene-related peptide-1	7KNU-CT Like-Calcitonin gene-related peptide-1-RAMP1
5.26	Single	7T9M	CS-17 Antibody	7T9M-TSH-CS-17 Antibody
5.26	Single	8HS2	Fab046	8HS2-GPR20-Fab046
5.13	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP1
5.00	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
5.00	Single	6W25	Ca	6W25-MC₄-SHU9119-Ca
5.00	Single	7FIG	hCG	7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
5.00	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/&β;1/&γ;2; RAMP1
5.00	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/&β;1/&γ;2
5.00	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2
5.00	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/&β;1/&γ;2; RAMP2
5.00	Single	7UTZ	TR1402	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
5.00	Single	7XW5	TSH	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
5.00	Single	7ZI0	Cholesterol	7ZI0-SMO-SAG-Cholesterol
5.00	Single	8TLM	Anti-murine CCR8 antibody	8TLM-CCR8-Anti-murine CCR8 antibody
5.00	Consensus	ccr8_off	Orthosteric Ligand	8TLM-CCR8-Anti-murine CCR8 antibody
4.88	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
4.76	Single	5L7D	Cholesterol	5L7D-SMO-Cholesterol
4.76	Single	7T9I	TSH	7T9I-TSH-TSH-Gs/&β;1/&γ;2
4.76	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/&β;1/&γ;2; RAMP3
4.76	Single	8HSC	Fab046	8HSC-GPR20-Fab046-Gi1/&β;1/&γ;2
4.76	Single	8I2G	Glycoprotein hormones alpha chain	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
4.76	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
4.65	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
4.65	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
4.55	Single	7Y14	Beta-alanine	7Y14-MRGPRD-Beta-alanine
4.44	Single	8F2A	Pramlintide analogue san385	8F2A-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
4.35	Single	7Y12	Beta-alanine	7Y12-MRGPRD-Beta-alanine-Gi1/&β;1/&γ;2
4.35	Consensus	gip_on_allo	Other Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
4.26	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/&β;1/&γ;2
4.17	Single	7XKF	Betahydroxyandrosterone	7XKF-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
4.17	Single	8F2B	Pramlintide analogue san45	8F2B-CT (AMY3)-Pramlintide analogue san45-Gs/&β;1/&γ;2; RAMP3
4.17	Single	8X2K	5YM	8X2K-GPR3-5YM-chim(NtGi1-Gs)/&β;1/&γ;2
4.00	Single	8F0J	Pramlintide analogue san45	8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2
3.85	Single	8HJ5	PubChem 139030531	8HJ5-MRGPRX1-PubChem 139030531-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
3.85	Single	8IYX	YL-365	8IYX-GPR34-YL-365
3.33	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
3.23	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
2.94	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
2.44	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/&β;1/&γ;2
2.33	Single	8F0K	Pramlintide analogue san385	8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3

Consensus Members
	Id	Members
	go_amine	go_adrenergic go_muscarinic go_5ht
	go_peptide	go_opioid go_ghrelin go_compl-peptide go_galanin go_vasopressin
	go_protein	go_chemokine

Net Summary
I_min	2.35387
Number of Linked Nodes	925
Number of Links	1095
Number of Hubs	161
Number of Links mediated by Hubs	630
Number of Communities	24
Number of Nodes involved in Communities	226
Number of Links involved in Communities	317

Path Summary
Number Of Nodes in MetaPath	105
Number Of Links MetaPath	104
Number of Shortest Paths	1672266
Length Of Smallest Path	3
Average Path Length	37.0154
Length of Longest Path	65
Minimum Path Strength	0.104206
Average Path Strength	4.51527
Maximum Path Strength	19.0111
Minimum Path Correlation	0.706611
Average Path Correlation	0.970677
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.69492
Average % Of Corr. Nodes	33.2027
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	47.7407
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

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