psnGPCR

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Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	G.HN.11	G.HN.33	2.86167	No	No	0	3	4
2	G.HN.30	G.HN.33	5.92607	No	No	0	8	4
3	G.HN.37	G.HN.41	3.31429	No	No	0	2	4
4	G.HN.37	b.b5x2	2.74726	No	Yes	0	2	7
5	G.HN.39	b.b5x5	3.8969	No	Yes	0	4	5
6	G.HN.40	b.b5x2	7.36131	No	Yes	0	7	7
7	G.HN.43	b.b5x3	5.2456	No	Yes	0	8	9
8	G.HN.44	b.b5x3	8.35714	No	Yes	0	6	9
9	G.HN.47	b.b4x2	3.94464	No	No	0	6	8
10	G.HN.47	b.b4x4	2.39524	No	Yes	0	6	8
11	G.HN.50	b.b4x2	6.37	No	No	0	5	8
12	G.S1.01	G.S3.02	9.07929	No	No	0	6	3
13	G.S1.02	G.S3.03	6.75762	Yes	Yes	18	4	7
14	G.S1.02	G.h2s4.05	4.8925	Yes	No	0	4	7
15	G.S1.03	G.S3.06	5.74286	No	Yes	0	9	6
16	G.S1.04	G.S4.03	3.19238	No	Yes	0	7	7
17	G.S1.05	G.S1.07	4.31643	No	No	0	9	9
18	G.S1.05	G.h2s4.01	8.74298	No	Yes	0	9	9
19	G.S1.05	G.S4.02	3.00702	No	No	0	9	7
20	G.H1.01	G.S1.06	4.95179	Yes	Yes	19	9	8
21	G.S1.06	G.S3.05	4.51464	Yes	No	0	8	6
22	G.S1.06	G.S3.07	2.43893	Yes	Yes	19	8	9
23	G.S1.06	G.S4.03	3.44714	Yes	Yes	0	8	7
24	G.H3.12	G.S1.07	3.90595	No	No	0	8	9
25	G.H1.01	G.s1h1.01	2.5731	Yes	No	0	9	9
26	G.H1.01	G.s1h1.05	2.62286	Yes	No	0	9	9
27	G.H1.03	G.s1h1.06	2.36167	No	No	0	9	9
28	G.H1.04	G.S5.05	3.30536	No	Yes	0	7	9
29	G.H1.08	G.S2.06	3.12464	No	No	0	8	8
30	G.hfs2.07	b.l7x4	3.33143	No	Yes	0	8	9
31	G.S2.01	G.S3.08	2.94345	No	No	0	9	9
32	G.S2.01	b.l5x5	7.70274	No	Yes	2	9	9
33	G.S2.02	G.S3.07	2.60714	No	Yes	0	5	9
34	G.S2.03	G.S3.04	9.22155	No	Yes	2	8	6
35	G.S2.03	G.S3.06	8.63345	No	Yes	2	8	6
36	G.S2.04	G.S3.05	3.45571	Yes	No	0	7	6
37	G.S2.05	G.S3.02	8.27488	Yes	No	0	3	3
38	G.S2.05	G.S3.04	3.10393	Yes	Yes	0	3	6
39	G.S2.06	G.S3.03	11.7115	No	Yes	0	8	7
40	G.S2.07	G.S3.02	3.26095	No	No	0	3	3
41	G.S2.08	G.s2s3.01	10.0286	Yes	Yes	14	5	4
42	G.H5.04	G.S2.08	6.50655	No	Yes	0	7	5
43	G.H5.05	G.S2.08	5.99476	Yes	Yes	14	5	5
44	G.H5.08	G.S2.08	6.11119	Yes	Yes	14	8	5
45	G.H5.08	G.s2s3.01	8.2706	Yes	Yes	14	8	4
46	G.S3.01	G.S3.03	5.34964	No	Yes	0	4	7
47	G.H5.08	G.S3.01	3.37845	Yes	No	0	8	4
48	G.H5.11	G.S3.03	2.8856	No	Yes	18	8	7
49	G.S3.04	G.S3.06	8.41071	Yes	Yes	2	6	6
50	G.S3.06	G.h2s4.01	3.01238	Yes	Yes	2	6	9
51	G.S3.06	b.l5x5	10.7506	Yes	Yes	2	6	9
52	G.H2.07	G.S3.08	7.82369	Yes	No	0	9	9
53	G.H2.07	G.s3h2.03	7.70631	Yes	Yes	2	9	9
54	G.s3h2.03	b.l7x4	3.52	Yes	Yes	0	9	9
55	G.s3h2.03	b.l9x6	5.60869	Yes	Yes	2	9	8
56	G.H2.02	b.l9x6	4.92119	No	Yes	2	8	8
57	G.H2.02	b.l13x6	4.47	No	Yes	2	8	9
58	G.H2.03	G.H2.05	10.8161	No	No	2	9	7
59	G.H2.04	G.H2.07	5.14238	No	Yes	0	9	9
60	G.H2.05	G.H2.06	4.49869	No	Yes	2	7	9
61	G.H2.06	b.l9x6	3.70869	Yes	Yes	2	9	8
62	G.H2.06	b.b14x1	7.71429	Yes	No	2	9	8
63	G.H2.06	b.l17x6	7.48881	Yes	Yes	2	9	9
64	G.H2.07	G.h2s4.01	2.65786	Yes	Yes	2	9	9
65	G.H2.07	b.l9x6	4.01929	Yes	Yes	2	9	8
66	G.H2.08	G.H3.17	2.43679	No	Yes	0	8	4
67	G.H2.09	G.H2.10	2.38702	Yes	No	2	8	6
68	G.H2.09	G.H3.17	6.15631	Yes	Yes	0	8	4
69	G.H2.09	b.b2x1	7.40071	Yes	Yes	2	8	8
70	G.H2.09	b.l28x1	4.40917	Yes	Yes	2	8	9
71	G.H2.10	b.b2x1	3.68036	No	Yes	2	6	8
72	G.H2.10	b.l3x1	2.6175	No	No	2	6	9
73	G.h2s4.01	b.l5x5	8.98524	Yes	Yes	2	9	9
74	G.h2s4.02	b.l1x6	7.05536	No	No	0	7	9
75	G.H3.18	G.S4.02	6.17583	Yes	No	0	9	7
76	G.S4.02	G.S5.02	3.52107	No	No	0	7	6
77	G.S4.03	G.S5.03	2.76667	Yes	No	0	7	8
78	G.S4.03	G.S5.05	2.45131	Yes	Yes	0	7	9
79	G.S4.04	G.S4.06	2.46405	No	Yes	0	9	7
80	G.H3.08	G.S4.04	2.95905	No	No	0	9	9
81	G.H3.09	G.S4.04	12.35	Yes	No	0	9	9
82	G.H3.05	G.S4.06	3.24964	No	Yes	0	9	7
83	G.S4.06	G.S5.06	2.89131	Yes	Yes	0	7	8
84	G.H4.15	G.S4.06	7.58571	Yes	Yes	0	8	7
85	G.S4.07	G.s4h3.05	2.75452	No	Yes	0	8	8
86	G.S5.06	G.s4h3.01	7.06964	Yes	No	0	8	7
87	G.HG.04	G.s4h3.01	7.68429	Yes	No	0	8	7
88	G.HG.03	G.s4h3.02	3.9494	Yes	No	20	6	9
89	G.H3.01	G.s4h3.05	7.57833	Yes	Yes	0	8	8
90	G.HG.07	G.s4h3.04	6.12655	No	Yes	0	9	8
91	G.H3.03	G.s4h3.15	4.58619	No	No	0	4	9
92	G.H3.03	G.hgh4.02	2.41107	No	Yes	9	4	8
93	G.H3.06	G.H4.15	7.39476	No	Yes	0	7	8
94	G.H3.06	G.h4s6.01	5.90857	No	Yes	0	7	4
95	G.H3.09	G.S5.02	4.63381	Yes	No	6	9	6
96	G.H3.09	G.S5.04	4.06095	Yes	Yes	6	9	9
97	G.H3.09	G.H4.15	6.31821	Yes	Yes	6	9	8
98	G.H3.10	G.H3.14	5.29119	No	No	0	4	8
99	G.H3.10	G.h4s6.01	12.0658	No	Yes	0	4	4
100	G.H3.13	G.S5.02	2.4925	No	No	6	5	6
101	G.H3.13	G.h4s6.11	3.6375	No	No	0	5	8
102	G.H3.14	G.h4s6.03	8.39333	No	No	0	8	4
103	G.H3.15	G.H3.18	3.58071	No	Yes	0	8	9
104	G.H3.16	G.H3.17	7.59191	No	Yes	0	4	4
105	G.H3.18	G.h3s5.03	7.27214	Yes	No	0	9	8
106	G.h3s5.01	G.h3s5.02	4.86667	No	No	0	2	4
107	G.h3s5.02	G.h4s6.10	3.62381	No	No	0	4	3
108	G.H5.14	G.S5.01	8.62571	No	No	0	6	7
109	G.H5.10	G.S5.03	3.19048	No	No	0	7	8
110	G.S5.04	G.S5.06	2.66869	Yes	Yes	0	9	8
111	G.H4.15	G.S5.04	3.66964	Yes	Yes	6	8	9
112	G.S5.04	G.S6.03	3.4006	Yes	No	6	9	4
113	G.S5.05	G.S6.04	4.16226	Yes	No	13	9	8
114	G.H5.03	G.S5.05	6.04083	No	Yes	13	8	9
115	G.H5.07	G.S5.05	2.87917	No	Yes	0	8	9
116	G.S5.06	G.S6.05	4.08845	Yes	No	0	8	5
117	G.S5.07	G.s6h5.01	3.35845	Yes	Yes	0	9	9
118	G.HG.03	G.s5hg.01	2.97107	Yes	Yes	20	6	9
119	G.HG.01	G.S6.05	3.30857	No	No	0	5	5
120	G.HG.01	G.s6h5.02	4.36774	No	No	0	5	7
121	G.HG.02	G.HG.03	2.64964	No	Yes	0	9	6
122	G.HG.02	G.s6h5.02	3.9825	No	No	0	9	7
123	G.H4.01	G.HG.14	4.26857	No	No	0	3	5
124	G.HG.15	G.hgh4.05	5.13595	No	Yes	0	7	6
125	G.hgh4.02	G.hgh4.04	2.40107	Yes	No	9	8	5
126	G.H4.10	G.hgh4.02	3.51167	Yes	Yes	9	6	8
127	G.H4.14	G.hgh4.02	3.26179	No	Yes	9	6	8
128	G.hgh4.05	G.hgh4.07	4.63893	Yes	No	0	6	8
129	G.H4.05	G.hgh4.05	3.27202	No	Yes	0	4	6
130	G.H4.10	G.hgh4.05	10.9565	Yes	Yes	0	6	6
131	G.hgh4.07	G.hgh4.08	4.06	No	No	0	8	1
132	G.H4.05	G.hgh4.08	11.0017	No	No	0	4	1
133	G.H4.03	G.H4.04	8.84369	Yes	No	0	3	4
134	G.H4.10	G.H4.14	6.87274	Yes	No	9	6	6
135	G.H4.12	G.H4.16	6.61393	No	Yes	6	5	3
136	G.H4.12	G.S6.03	9.70214	No	No	6	5	4
137	G.H4.16	G.S6.03	3.58286	Yes	No	6	3	4
138	G.H4.17	G.h4s6.01	2.84143	No	Yes	0	3	4
139	G.h4s6.02	G.h4s6.11	6.51107	No	No	0	7	8
140	G.S6.01	G.h4s6.02	4.36548	No	No	0	5	7
141	G.h4s6.08	G.h4s6.09	3.17857	No	No	0	5	4
142	G.H5.21	G.h4s6.10	6.85941	Yes	No	0	4	3
143	G.S6.02	G.h4s6.12	8.79226	Yes	No	0	8	4
144	G.H5.10	G.S6.02	3.33476	No	Yes	0	7	8
145	G.H5.13	G.S6.02	8.88107	No	Yes	0	7	8
146	G.S6.04	G.s6h5.01	3.96155	No	Yes	13	8	9
147	G.H5.06	G.S6.04	11.2355	No	No	0	3	8
148	G.H5.02	G.s6h5.05	2.40631	No	No	0	4	9
149	G.H5.05	G.H5.09	5.31476	Yes	No	0	5	4
150	G.H5.12	I2x51	3.20262	No	No	0	7	7
151	G.H5.15	G.H5.19	2.39655	No	No	0	8	8
152	G.H5.15	I2x51	2.47536	No	No	0	8	7
153	G.H5.16	I2x50	2.85762	No	No	0	7	9
154	G.H5.18	G.H5.21	5.15167	No	Yes	0	4	4
155	3x53	G.H5.19	5.015	No	No	0	9	8
156	G.H5.20	G.H5.25	2.75048	No	No	0	8	6
157	3x54	G.H5.20	4.23726	No	No	0	8	8
158	G.H5.21	G.H5.26	5.20774	Yes	No	0	4	5
159	3x50	G.H5.23	7.1956	Yes	No	0	9	4
160	6x29	G.H5.26	9.30738	No	No	0	8	5
161	b.1x11	b.1x14	3.52381	Yes	No	0	8	4
162	b.1x11	g.h1x12	3.96143	Yes	No	0	8	6
163	b.1x12	g.h1x11	2.45071	No	No	0	6	9
164	b.1x13	b.1x16	6.29869	No	No	0	1	4
165	b.1x15	b.1x19	3.99595	No	Yes	0	7	6
166	b.1x18	g.l1x4	2.70214	No	Yes	0	4	8
167	b.1x19	g.l1x4	2.38679	Yes	Yes	4	6	8
168	b.1x22	g.l1x4	2.83536	No	Yes	0	3	8
169	b.h2x2	b.lh12x4	2.49524	No	No	0	1	3
170	b.h2x3	b.lh12x4	4.11536	No	No	0	1	3
171	b.h2x1	b.h2x5	3.35214	Yes	Yes	0	5	5
172	b.b21x5	b.h2x1	4.72976	Yes	Yes	0	4	5
173	b.h2x1	g.h2x5	2.96631	Yes	No	0	5	6
174	b.h2x5	b.l24x2	2.66571	Yes	No	0	5	6
175	b.h2x5	g.h2x9	2.49321	Yes	No	0	5	4
176	b.lhb1x4	b.lhb1x5	3.18167	No	No	0	1	1
177	b.l22x5	b.lhb1x6	5.77667	Yes	Yes	10	9	3
178	b.b24x7	b.lhb1x6	7.18	No	Yes	10	9	3
179	b.lhb1x10	b.lhb1x8	3.39405	No	No	0	4	2
180	b.lhb1x11	b.lhb1x9	2.36333	No	No	0	4	3
181	b.b23x1	b.lhb1x9	2.6506	Yes	No	0	5	3
182	b.b25x7	b.lhb1x11	3.24798	No	No	0	7	4
183	b.lhb1x11	g.ctx5	3.29821	No	No	0	4	9
184	b.b1x1	b.b1x3	3.36429	No	Yes	0	5	7
185	b.b1x2	b.b28x4	6.89917	No	Yes	8	3	6
186	b.b1x2	b.b28x6	8.84929	No	Yes	8	3	9
187	b.b1x3	b.b28x7	5.98607	Yes	No	3	7	9
188	b.b1x3	g.ctx16	3.13274	Yes	Yes	3	7	8
189	b.b1x4	b.b5x1	4.51048	No	No	0	7	5
190	b.b1x4	b.b28x5	4.04179	No	No	3	7	5
191	b.b1x4	g.ctx16	4.86226	No	Yes	3	7	8
192	b.b1x5	b.l1x1	7.22298	No	No	0	3	7
193	b.b1x5	b.b28x4	5.02179	No	Yes	0	3	6
194	b.b1x6	b.b4x6	18.6157	No	Yes	0	9	9
195	b.b1x6	b.b5x1	3.54452	No	No	0	9	5
196	b.b1x6	b.b28x3	6.88917	No	Yes	0	9	7
197	b.b28x2	b.l1x1	5.52262	No	No	0	4	7
198	b.b5x3	b.l1x2	2.5325	Yes	No	0	9	9
199	b.l1x3	b.l1x7	8.23524	Yes	No	3	9	9
200	b.b3x4	b.l1x3	6.60774	No	Yes	0	9	9
201	b.b3x6	b.l1x3	11.5721	No	Yes	3	9	9
202	b.b4x4	b.l1x3	10.7331	Yes	Yes	3	8	9
203	b.l1x4	b.l3x2	3.65298	No	Yes	0	6	9
204	b.b2x1	b.l1x6	6.48321	Yes	No	2	8	9
205	b.l1x6	b.l28x1	21.7021	No	Yes	2	9	9
206	b.b3x6	b.l1x7	2.37988	No	No	3	9	9
207	b.b28x3	b.l1x7	2.44607	Yes	No	0	7	9
208	b.b2x1	b.l3x1	13.1121	Yes	No	2	8	9
209	b.b2x3	b.b2x5	3.97298	No	Yes	3	6	7
210	b.b26x2	b.b2x3	5.265	No	No	0	7	6
211	b.b2x4	b.b6x5	3.10131	No	Yes	0	6	6
212	b.b10x4	b.b2x4	13.0724	No	No	0	6	6
213	b.b2x5	b.b3x2	8.17488	Yes	No	3	7	5
214	b.b2x5	b.l4x1	4.51583	Yes	No	3	7	5
215	b.b26x4	b.b2x5	2.51	No	Yes	0	5	7
216	b.b2x5	b.l27x1	10.8726	Yes	No	3	7	7
217	b.b27x2	b.b2x5	4.07571	No	Yes	0	5	7
218	b.b6x5	b.l2x1	4.67405	Yes	No	0	6	5
219	b.l27x2	b.l2x2	3.0631	No	No	0	1	1
220	b.l2x3	b.l2x5	4.67631	No	No	0	8	5
221	b.l27x1	b.l2x4	7.80298	No	No	3	7	5
222	b.l27x3	b.l2x4	9.25464	No	No	3	7	5
223	b.b4x7	b.l2x5	12.9875	No	No	0	8	5
224	b.l2x5	b.l4x2	23.861	No	Yes	0	5	4
225	b.b3x1	b.b6x5	2.74738	No	Yes	0	5	6
226	b.b3x2	b.b4x6	4.42048	No	Yes	3	5	9
227	b.b3x3	b.b4x3	2.90905	No	Yes	0	8	7
228	b.b3x3	b.b4x5	4.24083	No	Yes	0	8	7
229	b.b3x3	b.b6x5	4.7175	No	Yes	0	8	6
230	b.b3x4	b.b4x6	5.1919	No	Yes	0	9	9
231	b.b28x3	b.b3x4	2.9125	Yes	No	0	7	9
232	b.b3x5	b.l5x6	3.02917	No	No	0	9	9
233	b.b3x5	b.b6x3	2.96667	No	No	0	9	8
234	b.b3x6	b.l3x2	7.69333	No	Yes	3	9	9
235	b.l3x1	b.l5x5	4.18607	No	Yes	2	9	9
236	b.b4x2	b.l3x2	5.68036	No	Yes	0	8	9
237	b.b4x1	b.l5x1	2.9925	No	Yes	0	8	8
238	b.b4x3	b.b5x7	4.39869	Yes	Yes	0	7	7
239	b.b4x3	b.l5x1	4.84512	Yes	Yes	11	7	8
240	b.b4x3	b.b7x4	3.9494	Yes	Yes	11	7	8
241	b.b4x4	b.b4x6	12.8483	Yes	Yes	3	8	9
242	b.b4x4	b.b5x3	3.59941	Yes	Yes	3	8	9
243	b.b4x5	b.b5x4	3.58452	Yes	No	17	7	5
244	b.b4x5	b.b5x5	5.68012	Yes	Yes	17	7	5
245	b.b4x5	b.l8x1	2.39393	Yes	No	0	7	5
246	b.b4x6	b.b5x3	9.83238	Yes	Yes	3	9	9
247	b.b4x7	b.l4x3	8.72571	No	No	0	8	6
248	b.l4x1	b.l4x2	2.67833	No	Yes	3	5	4
249	b.l4x1	g.ctx16	4.27476	No	Yes	3	5	8
250	b.l4x2	g.ctx15	10.5814	Yes	Yes	3	4	9
251	b.l4x2	g.ctx16	5.39214	Yes	Yes	3	4	8
252	b.b5x2	b.l4x3	9.36833	Yes	No	0	7	6
253	b.b5x4	b.b5x5	5.68536	No	Yes	17	5	5
254	b.b5x5	b.l8x8	3.37643	Yes	No	0	5	4
255	b.b5x7	b.b5x8	3.39	Yes	No	0	7	5
256	b.b5x7	b.b8x4	5.58631	Yes	Yes	0	7	6
257	b.b5x7	b.l8x8	7.07702	Yes	No	0	7	4
258	b.l5x1	b.l5x6	2.87357	Yes	No	11	8	9
259	b.b7x4	b.l5x1	4.53452	Yes	Yes	11	8	8
260	b.b8x4	b.l5x1	4.18857	Yes	Yes	11	6	8
261	b.b9x3	b.l5x2	5.71929	No	No	0	6	6
262	b.l5x3	b.l7x3	8.57131	No	No	0	8	9
263	b.l5x5	b.l7x2	4.32548	Yes	Yes	2	9	9
264	b.b6x1	b.l7x1	2.62	No	No	0	9	9
265	b.b6x1	b.l9x6	3.86262	No	Yes	0	9	8
266	b.b10x2	b.b6x2	2.49476	No	No	0	6	8
267	b.b6x5	b.l6x4	4.55333	Yes	No	0	6	5
268	b.b6x5	b.b7x2	2.44714	Yes	No	0	6	8
269	b.b10x5	b.l6x1	6.76929	Yes	No	0	9	6
270	b.b10x5	b.l6x2	2.52607	Yes	No	0	9	6
271	b.l6x3	b.l6x5	7.73381	No	Yes	15	6	4
272	b.l10x3	b.l6x3	7.58714	No	No	15	6	6
273	b.b7x1	b.l6x5	4.09857	Yes	Yes	15	4	4
274	b.l6x5	b.l8x2	7.57607	Yes	No	0	4	4
275	b.l10x3	b.l6x5	3.04774	No	Yes	15	6	4
276	b.b7x1	b.b8x3	3.51476	Yes	No	0	4	6
277	b.b7x1	b.b8x5	9.42845	Yes	No	0	4	4
278	b.b7x1	b.l10x3	7.28333	Yes	No	15	4	6
279	b.b7x2	b.b8x4	3.45869	No	Yes	0	8	6
280	b.b7x2	b.l8x1	3.5831	No	No	0	8	5
281	b.b10x5	b.b7x3	3.54774	Yes	No	0	9	9
282	b.b7x4	b.b8x4	2.86333	Yes	Yes	11	8	6
283	b.l7x2	b.l9x6	2.53714	Yes	Yes	2	9	8
284	b.l7x3	b.l7x5	6.28286	No	No	0	9	6
285	b.l7x4	b.l9x5	3.95762	Yes	No	0	9	8
286	b.b9x3	b.l7x5	3.46619	No	No	0	6	6
287	b.b8x1	b.l9x7	2.6625	Yes	No	2	8	7
288	b.b10x3	b.b8x1	2.535	No	Yes	2	8	8
289	b.b11x4	b.b8x1	2.93738	Yes	Yes	2	9	8
290	b.b8x2	b.b9x3	2.73833	No	No	0	8	6
291	b.b8x3	b.l12x1	4.17095	No	No	0	6	6
292	b.b8x4	b.l8x10	5.30417	Yes	No	0	6	4
293	b.l8x1	b.l8x8	2.94452	No	No	0	5	4
294	b.l8x3	b.l8x5	2.66893	Yes	Yes	21	3	3
295	b.l8x3	b.l8x9	3.43262	Yes	No	21	3	3
296	b.l8x5	b.l8x7	3.2694	Yes	No	0	3	3
297	b.l8x5	b.l8x9	5.30298	Yes	No	21	3	3
298	b.b12x6	b.b9x4	16.6224	Yes	No	0	8	9
299	b.b12x6	b.l9x2	2.52929	Yes	No	0	8	5
300	b.l9x3	b.l9x7	2.6644	Yes	No	2	9	7
301	b.b11x4	b.l9x3	5.6431	Yes	Yes	2	9	9
302	b.b11x6	b.l9x3	14.9948	No	Yes	2	9	9
303	b.l11x2	b.l9x3	7.56095	Yes	Yes	2	9	9
304	b.b12x2	b.l9x3	2.7069	No	Yes	2	7	9
305	b.b12x4	b.l9x3	2.86	No	Yes	2	4	9
306	b.b12x6	b.l9x3	3.1731	Yes	Yes	2	8	9
307	b.l11x2	b.l9x4	7.45143	Yes	No	0	9	5
308	b.l11x1	b.l9x6	5.58893	No	Yes	2	9	8
309	b.l13x6	b.l9x6	7.96548	Yes	Yes	2	9	8
310	b.b14x1	b.l9x6	3.02071	No	Yes	2	8	8
311	b.b11x4	b.l9x7	4.08964	Yes	No	2	9	7
312	b.b10x1	b.b11x5	2.96893	No	No	0	9	6
313	b.b10x2	b.b14x3	3.45536	No	Yes	0	6	5
314	b.b10x3	b.b11x4	2.75631	No	Yes	2	8	9
315	b.b10x4	b.b14x5	3.00655	No	No	0	6	5
316	b.b10x5	b.b11x2	7.87988	Yes	No	0	9	7
317	b.b11x1	b.l10x1	5.35298	No	Yes	0	5	3
318	b.b11x3	b.l10x1	2.71393	No	Yes	0	5	3
319	b.b14x5	b.l10x1	4.795	No	Yes	0	5	3
320	b.l10x1	b.l14x4	3.4375	Yes	No	0	3	1
321	b.l10x2	b.l10x4	4.10214	No	No	0	5	3
322	b.b11x1	b.l10x2	7.77024	No	No	0	5	5
323	b.l10x4	b.l12x2	8.38714	No	No	22	3	6
324	b.b11x1	b.b12x5	2.66	No	No	0	5	6
325	b.b11x2	b.b12x6	3.38036	No	Yes	0	7	8
326	b.b11x2	b.l12x1	2.9269	No	No	0	7	6
327	b.b11x3	b.b14x3	2.99774	No	Yes	5	5	5
328	b.b11x3	b.b15x1	3.6025	No	Yes	5	5	9
329	b.b11x4	b.b12x6	8.86452	Yes	Yes	2	9	8
330	b.b11x5	b.l13x7	4.38762	No	No	0	6	9
331	b.b11x5	b.b14x3	4.32667	No	Yes	0	6	5
332	b.b11x6	b.l11x1	3.22548	No	No	2	9	9
333	b.b11x6	b.l11x2	8.62381	No	Yes	2	9	9
334	b.l11x1	b.l13x6	4.59131	No	Yes	2	9	9
335	b.b12x2	b.l11x2	9.60024	No	Yes	2	7	9
336	b.b12x3	b.b13x7	4.25714	No	Yes	0	8	7
337	b.b12x4	b.b12x6	4.36964	No	Yes	2	4	8
338	b.b12x4	b.b13x3	5.57464	No	No	2	4	4
339	b.b12x5	b.b13x4	2.56024	No	No	5	6	4
340	b.b12x6	b.b13x3	12.8817	Yes	No	2	8	4
341	b.b12x7	b.l12x2	5.11988	No	No	22	9	6
342	b.b12x7	b.l12x3	11.4429	No	No	0	9	5
343	b.b13x2	b.l12x3	4.20131	No	No	0	4	5
344	b.b13x4	b.b13x5	3.10262	No	No	5	4	4
345	b.b13x5	b.b13x7	4.6169	No	Yes	5	4	7
346	b.b13x7	b.b15x1	8.83071	Yes	Yes	5	7	9
347	b.b13x7	b.b16x6	14.1269	Yes	Yes	5	7	8
348	b.b13x7	b.b17x1	3.60321	Yes	No	0	7	4
349	b.l13x3	b.l13x7	5.05774	Yes	No	0	9	9
350	b.b15x3	b.l13x3	5.64619	No	Yes	5	9	9
351	b.b15x5	b.l13x3	7.31679	No	Yes	5	8	9
352	b.b16x4	b.l13x3	15.5173	Yes	Yes	5	6	9
353	b.b16x6	b.l13x3	3.48798	Yes	Yes	5	8	9
354	b.l13x4	b.l15x2	5.09321	No	Yes	0	3	9
355	b.l13x6	b.l15x1	3.2975	Yes	Yes	2	9	7
356	b.b14x1	b.l15x1	3.24	No	Yes	2	8	7
357	b.b14x2	b.b18x3	4.75476	No	Yes	0	7	8
358	b.b14x3	b.b15x1	4.61083	Yes	Yes	5	5	9
359	b.b14x4	b.b18x5	6.63917	No	Yes	0	8	5
360	b.b18x5	b.l14x1	5.26548	Yes	No	0	5	4
361	b.l14x2	b.l18x4	2.51333	No	No	0	4	7
362	b.l14x3	b.l14x5	9.00202	No	No	0	5	5
363	b.l14x5	b.l16x2	5.71155	No	No	0	5	9
364	b.b16x5	b.l14x6	3.78964	Yes	No	0	5	3
365	b.b15x1	b.b16x6	11.7761	Yes	Yes	5	9	8
366	b.b15x1	b.l16x1	2.55762	Yes	No	0	9	4
367	b.b15x2	b.b16x5	2.94452	Yes	Yes	0	6	5
368	b.b15x2	b.b18x3	5.1925	Yes	Yes	4	6	8
369	b.b15x2	b.b18x5	7.85131	Yes	Yes	4	6	5
370	b.b15x2	b.b19x2	5.67976	Yes	Yes	4	6	6
371	b.b15x3	b.b16x6	5.82286	No	Yes	5	9	8
372	b.b15x4	b.l17x7	3.54929	No	No	0	6	7
373	b.b15x5	b.l15x2	3.14452	No	Yes	5	8	9
374	b.l15x1	b.l17x6	6.98381	Yes	Yes	2	7	9
375	b.b16x2	b.l15x2	8.73048	No	Yes	0	5	9
376	b.b16x4	b.b16x6	7.01524	Yes	Yes	5	6	8
377	b.b16x4	b.b17x3	6.44821	Yes	No	5	6	5
378	b.b16x4	b.b17x6	10.7967	Yes	No	0	6	7
379	b.b16x5	b.b17x5	4.29179	Yes	Yes	0	5	7
380	b.b16x5	b.l20x1	5.12476	Yes	No	0	5	6
381	b.b16x6	b.b17x3	5.36274	Yes	No	5	8	5
382	b.b16x7	b.l16x3	9.23286	No	Yes	23	9	3
383	b.b16x7	b.b17x4	9.00452	No	No	23	9	5
384	b.b17x2	b.l16x3	8.57024	No	Yes	0	3	3
385	b.b17x3	g.h1x10	4.97679	No	No	0	5	9
386	b.b17x5	b.b17x7	7.09833	Yes	Yes	4	7	8
387	b.b17x5	b.b21x1	10.9846	Yes	Yes	4	7	7
388	b.b17x6	g.h1x14	7.79631	No	No	0	7	9
389	b.b17x7	b.b19x2	8.90464	Yes	Yes	4	8	6
390	b.b17x7	b.b20x6	8.08893	Yes	Yes	4	8	6
391	b.b17x7	b.b21x1	4.40762	Yes	Yes	4	8	7
392	b.l17x3	b.l17x7	5.66643	Yes	No	4	9	7
393	b.b19x6	b.l17x3	11.5896	No	Yes	4	9	9
394	b.b20x4	b.l17x3	14.7648	Yes	Yes	4	8	9
395	b.l17x4	b.l19x2	4.14667	No	Yes	0	3	9
396	b.l17x5	b.l19x2	3.62524	No	Yes	0	6	9
397	b.b19x4	b.l17x7	3.87238	Yes	No	4	8	7
398	b.b18x1	b.l19x1	7.58119	No	No	2	9	9
399	b.b18x2	b.b22x3	3.3531	No	No	0	5	6
400	b.b18x3	b.b19x2	4.64893	Yes	Yes	4	8	6
401	b.b18x3	b.b19x4	4.1619	Yes	Yes	4	8	8
402	b.b18x5	b.b19x2	2.60214	Yes	Yes	4	5	6
403	b.l18x1	b.l18x2	9.45762	Yes	Yes	7	6	7
404	b.b19x1	b.l18x1	2.65548	No	Yes	0	6	6
405	b.b22x5	b.l18x1	9.32607	Yes	Yes	7	7	6
406	b.l18x1	b.l22x4	4.22905	Yes	No	7	6	9
407	b.l18x1	g.h2x8	4.97393	Yes	No	0	6	7
408	b.l18x1	g.h2x11	3.48714	Yes	Yes	7	6	6
409	b.l18x2	g.h2x11	5.26214	Yes	Yes	7	7	6
410	b.l18x3	b.l18x5	8.75833	No	No	0	5	2
411	b.b19x2	b.b20x6	9.77429	Yes	Yes	4	6	6
412	b.b19x3	b.b22x5	2.96857	No	Yes	7	4	7
413	b.b19x4	b.b20x6	5.47929	Yes	Yes	4	8	6
414	b.b19x5	b.l21x9	5.01583	No	No	0	5	6
415	b.b19x6	b.l19x2	5.97476	No	Yes	4	9	9
416	b.b20x2	b.l19x2	7.00464	No	Yes	0	6	9
417	b.b20x2	b.b20x4	6.42179	No	Yes	0	6	8
418	b.b20x3	b.b21x7	3.90238	No	Yes	0	8	5
419	b.b20x3	b.l21x9	3.50774	No	No	0	8	6
420	b.b20x4	b.b20x6	2.675	Yes	Yes	4	8	6
421	b.b20x4	b.b21x3	14.5663	Yes	No	4	8	6
422	b.b20x4	b.b21x6	8.64	Yes	No	4	8	1
423	b.b20x5	b.b21x4	3.29536	No	Yes	0	7	5
424	b.b20x5	b.b21x7	5.31631	No	Yes	0	7	5
425	b.b20x6	b.b21x3	6.02274	Yes	No	4	6	6
426	b.b20x7	b.l20x3	4.0425	No	No	0	9	7
427	b.b20x7	b.b21x4	4.79905	No	Yes	0	9	5
428	b.b20x7	g.h2x4	3.65738	No	No	0	9	7
429	b.l20x2	g.l1x5	9.08155	No	No	0	9	4
430	b.b21x3	b.b21x6	4.46726	No	No	4	6	1
431	b.b21x5	b.b21x7	9.72071	Yes	Yes	0	4	5
432	b.b21x5	b.b25x1	3.45	Yes	No	0	4	2
433	b.b21x7	b.b23x2	5.21988	Yes	No	0	5	6
434	b.b21x7	b.b24x6	8.03798	Yes	Yes	0	5	8
435	b.l21x2	b.l21x4	10.4764	Yes	No	0	4	4
436	b.l21x2	b.l21x5	3.725	Yes	No	0	4	4
437	b.b23x6	b.l21x5	5.35381	Yes	No	0	7	4
438	b.l21x7	b.l23x2	5.61155	No	No	0	5	8
439	b.b23x6	b.l21x9	8.85071	Yes	No	0	7	6
440	b.b22x2	b.b26x3	6.47202	No	No	0	8	6
441	b.b22x4	b.b26x5	4.06083	No	No	0	5	7
442	b.b22x5	b.b23x2	9.005	Yes	No	7	7	6
443	b.l22x1	g.ctx3	7.88738	No	Yes	0	9	9
444	b.l22x1	g.ctx5	3.21857	No	No	0	9	9
445	b.l22x3	g.ctx3	9.32488	No	Yes	0	9	9
446	b.b24x7	b.l22x5	12.8883	No	Yes	10	9	9
447	b.l22x5	b.l24x2	6.30405	Yes	No	10	9	6
448	b.l22x5	g.h2x12	2.43702	Yes	No	10	9	7
449	b.l22x5	g.ctx6	4.53893	Yes	Yes	0	9	6
450	b.b23x1	b.b24x5	4.82476	Yes	No	0	5	5
451	b.b23x1	g.ctx6	3.82345	Yes	Yes	0	5	6
452	b.b23x3	b.b24x5	3.5831	No	No	0	7	5
453	b.b23x3	b.b27x1	4.20393	No	No	0	7	6
454	b.b23x4	b.b23x6	3.57333	No	Yes	0	6	7
455	b.b23x5	b.l25x7	2.51905	No	No	0	7	7
456	b.b23x6	b.b24x4	9.6769	Yes	Yes	16	7	6
457	b.b23x6	b.b24x6	5.10941	Yes	Yes	16	7	8
458	b.l23x1	b.l25x6	19.2857	Yes	No	0	6	8
459	b.b24x2	b.l23x2	6.52321	No	No	0	5	8
460	b.b24x1	b.l25x5	2.90619	No	No	0	4	7
461	b.b24x2	b.b25x6	3.25393	No	No	0	5	3
462	b.b24x3	b.b25x7	4.34405	No	No	0	5	7
463	b.b24x4	b.b24x6	2.50214	Yes	Yes	16	6	8
464	b.b24x4	b.b25x3	8.20679	Yes	No	16	6	5
465	b.b24x4	b.b25x6	3.36202	Yes	No	0	6	3
466	b.b24x6	b.b25x3	3.20238	Yes	No	16	8	5
467	b.b24x7	b.l24x3	7.63679	No	Yes	0	9	5
468	b.l24x2	g.h2x12	4.11869	No	No	10	6	7
469	b.b25x2	b.l24x3	3.52262	No	Yes	0	2	5
470	b.b25x7	b.b28x6	14.658	No	Yes	0	7	9
471	b.l25x3	b.l25x7	3.97083	Yes	No	8	9	7
472	b.b27x3	b.l25x3	6.36024	No	Yes	0	8	9
473	b.b27x5	b.l25x3	14.0127	No	Yes	8	9	9
474	b.l25x3	b.l28x2	8.74726	Yes	Yes	8	9	9
475	b.b28x4	b.l25x3	8.24988	Yes	Yes	8	6	9
476	b.l25x4	b.l28x2	4.87762	No	Yes	0	5	9
477	b.l25x6	b.l28x1	20.5381	No	Yes	0	8	9
478	b.b26x1	b.l28x1	5.58691	No	Yes	0	9	9
479	b.b26x3	b.b27x3	3.475	No	No	0	6	8
480	b.b26x5	b.b27x1	3.47452	No	No	0	7	6
481	b.l27x1	b.l27x3	6.8681	No	No	3	7	7
482	b.l27x3	b.l27x5	7.42595	No	No	0	7	5
483	b.l27x5	g.ctx4	4.95048	No	No	0	5	7
484	b.l27x5	g.ctx15	3.59464	No	Yes	0	5	9
485	b.l27x6	g.ctx16	4.02762	No	Yes	0	7	8
486	b.b27x3	b.b28x6	7.37821	No	Yes	0	8	9
487	b.b27x5	b.l28x2	7.36119	No	Yes	8	9	9
488	b.b28x2	b.l28x2	8.31798	No	Yes	0	4	9
489	b.b28x1	b.b28x2	3.56881	No	No	0	4	4
490	b.b28x4	b.b28x6	7.44333	Yes	Yes	8	6	9
491	b.b28x5	g.ctx16	4.37929	No	Yes	3	5	8
492	b.b28x7	g.ctx14	9.6169	No	No	0	9	9
493	b.b28x7	g.ctx16	3.88238	No	Yes	3	9	8
494	g.h1x1	g.h1x5	2.89202	No	No	0	2	6
495	g.h1x10	g.h1x14	5.355	No	No	0	9	9
496	g.l1x2	g.l1x4	6.4275	No	Yes	0	2	8
497	g.h2x3	g.l1x5	3.35798	No	No	0	5	4
498	g.h2x2	g.l1x6	2.60464	No	No	24	9	4
499	g.h2x11	g.h2x15	15.374	Yes	No	0	6	6
500	g.ctx1	g.ctx2	3.98571	No	No	0	1	3
501	g.ctx3	g.ctx4	3.7375	Yes	No	0	9	7
502	g.ctx3	g.ctx6	8.73976	Yes	Yes	0	9	6
503	g.ctx7	g.ctx8	2.75	No	No	0	4	8
504	g.ctx10	g.ctx9	3.24012	No	No	0	5	6
505	g.ctx14	g.ctx9	2.88476	No	No	0	9	6
506	g.ctx12	g.ctx13	2.56512	No	No	0	6	5
507	g.ctx14	g.ctx15	5.6856	No	Yes	0	9	9
508	g.ctx15	g.ctx16	4.57429	Yes	Yes	3	9	8
509	1x39	2x61	3.2531	No	No	0	5	8
510	1x46	1x50	2.54071	No	Yes	0	8	9
511	1x46	2x54	2.94952	No	No	0	8	9
512	1x46	7x47	4.55833	No	Yes	0	8	8
513	1x49	7x50	2.885	No	No	0	9	9
514	1x50	2x47	3.05179	Yes	No	0	9	9
515	1x50	2x50	9.82405	Yes	Yes	0	9	9
516	1x50	2x51	3.07214	Yes	No	0	9	8
517	1x50	7x50	6.47988	Yes	No	0	9	9
518	1x52	8x54	8.2494	No	Yes	0	8	8
519	1x54	2x47	2.42869	No	No	0	8	9
520	1x56	8x54	2.57345	No	Yes	0	9	8
521	1x57	2x44	3.51441	No	No	0	8	7
522	1x60	I1x50	4.69345	No	Yes	0	8	9
523	I1x48	I1x51	2.98274	No	No	0	8	7
524	2x40	I1x50	2.83167	No	Yes	25	9	9
525	8x49	I1x50	4.69893	No	Yes	0	8	9
526	8x50	I1x50	11.4388	Yes	Yes	25	8	9
527	2x37	2x40	4.47107	No	No	0	8	9
528	2x38	I2x57	3.76441	No	Yes	0	7	7
529	2x39	3x49	3.82512	No	Yes	12	9	9
530	2x39	I2x57	3.7181	No	Yes	12	9	7
531	2x40	8x50	3.51607	No	Yes	25	9	8
532	2x41	4x42	2.83726	No	No	0	8	8
533	2x42	3x46	3.16464	Yes	No	0	8	9
534	2x42	4x42	4.01667	Yes	No	0	8	8
535	2x42	4x46	3.46179	Yes	No	0	8	8
536	2x45	3x42	7.43357	Yes	Yes	1	9	8
537	2x45	4x46	4.75548	Yes	No	0	9	8
538	2x45	4x50	3.60512	Yes	Yes	1	9	9
539	2x46	3x42	3.19774	Yes	Yes	1	9	8
540	2x46	3x43	3.11	Yes	Yes	1	9	8
541	2x46	7x49	4.96869	Yes	Yes	1	9	9
542	2x49	4x50	2.44024	No	Yes	0	8	9
543	2x50	7x46	7.3975	Yes	No	0	9	9
544	2x52	3x35	6.52583	No	No	0	8	7
545	2x53	2x56	3.1431	No	No	0	8	8
546	2x53	3x35	3.54071	No	No	0	8	7
547	2x53	7x46	3.28714	No	No	0	8	9
548	2x54	2x57	2.60357	No	Yes	0	9	8
549	2x56	3x32	7.93	No	No	1	8	8
550	2x56	7x42	4.24429	No	Yes	1	8	8
551	2x57	7x39	3.92238	Yes	Yes	1	8	7
552	2x57	7x42	4.78012	Yes	Yes	1	8	8
553	2x59	3x28	8.36393	No	Yes	0	7	7
554	2x60	3x28	3.30798	Yes	Yes	0	8	7
555	2x60	7x39	4.0744	Yes	Yes	1	8	7
556	2x63	E1x50	5.7369	No	Yes	1	8	8
557	2x64	7x35	3.63238	No	No	0	7	7
558	2x66	E1x49	3.09321	No	No	0	7	5
559	E1x50	E1x52	3.66988	Yes	No	1	8	7
560	3x25	E1x50	6.57643	No	Yes	1	9	8
561	E1x50	E2x50	7.27488	Yes	No	1	8	9
562	E1x51	E1x52	2.4825	Yes	No	1	5	7
563	3x24	E1x52	5.94524	No	No	0	6	7
564	3x25	E2x50	6.32667	No	No	1	9	9
565	3x28	3x29	3.74202	Yes	No	0	7	7
566	3x29	E2x50	2.50512	No	No	0	7	9
567	3x32	7x42	7.66417	No	Yes	1	8	8
568	3x32	Lig	10.1232	No	Yes	1	8	0
569	3x33	4x57	6.39714	No	Yes	1	8	8
570	3x33	Lig	9.64226	No	Yes	1	8	0
571	3x34	4x53	2.45417	No	No	0	7	8
572	3x34	4x57	3.19643	No	Yes	0	7	8
573	3x36	6x48	3.56321	No	Yes	1	7	9
574	3x36	Lig	8.59143	No	Yes	1	7	0
575	3x37	3x41	3.91571	Yes	Yes	0	8	7
576	3x37	4x53	5.06464	Yes	No	0	8	8
577	3x37	Lig	2.545	Yes	Yes	1	8	0
578	3x38	4x50	7.23488	No	Yes	0	8	9
579	3x40	6x48	7.3275	No	Yes	0	9	9
580	3x41	4x49	2.61988	Yes	No	0	7	8
581	3x42	4x49	4.06488	Yes	No	0	8	8
582	3x43	6x44	2.90845	Yes	Yes	1	8	9
583	3x43	7x49	3.45917	Yes	Yes	1	8	9
584	3x43	7x53	6.54381	Yes	Yes	1	8	9
585	3x46	3x50	4.96524	No	Yes	1	9	9
586	3x47	5x58	4.88083	No	Yes	0	9	8
587	3x48	3x52	4.05631	No	Yes	0	7	6
588	3x49	I2x53	6.00881	Yes	Yes	12	9	9
589	3x49	I2x57	6.80524	Yes	Yes	12	9	7
590	3x51	3x55	10.7124	Yes	No	0	8	7
591	3x52	3x56	2.58536	Yes	No	0	6	7
592	3x52	I2x53	11.658	Yes	Yes	0	6	9
593	3x55	3x56	2.8356	No	No	0	7	7
594	I2x53	I2x57	10.1252	Yes	Yes	12	9	7
595	4x38	4x40	2.80548	No	No	0	8	5
596	4x58	4x59	2.62571	No	No	0	6	8
597	5x36	E2	5.48274	Yes	Yes	1	5	7
598	5x47	6x52	16.6067	Yes	Yes	1	8	8
599	5x48	6x52	2.47988	Yes	Yes	1	9	8
600	5x53	5x57	2.3769	No	Yes	26	5	5
601	5x55	6x41	3.17429	No	No	0	9	7
602	6x36	7x56	5.81369	No	No	0	8	8
603	6x40	7x53	4.91309	No	Yes	1	8	9
604	6x43	7x52	3.00607	No	Yes	0	8	8
605	6x44	6x48	3.8031	Yes	Yes	1	9	9
606	6x45	6x49	3.59988	No	Yes	0	7	7
607	6x47	7x45	8.62369	No	No	0	8	9
608	6x48	6x52	5.30107	Yes	Yes	1	9	8
609	6x48	7x41	6.58167	Yes	No	0	9	8
610	6x48	7x45	8.59607	Yes	No	0	9	9
611	6x48	Lig	4.58667	Yes	Yes	1	9	0
612	6x49	6x50	2.97774	Yes	No	0	7	9
613	6x49	6x53	2.93429	Yes	No	0	7	7
614	6x50	7x37	6.63286	No	No	0	9	7
615	6x51	6x52	4.88119	Yes	Yes	1	8	8
616	6x51	6x55	5.405	Yes	No	1	8	8
617	6x51	7x38	5.06238	Yes	Yes	1	8	7
618	6x51	Lig	12.1905	Yes	Yes	1	8	0
619	6x54	7x37	3.9806	No	No	0	7	7
620	6x55	Lig	4.29536	No	Yes	1	8	0
621	6x57	E3	3.46179	No	Yes	0	7	5
622	7x30	E3	3.04607	No	Yes	0	7	5
623	7x38	7x42	5.75417	Yes	Yes	1	7	8
624	7x38	Lig	9.15774	Yes	Yes	1	7	0
625	7x39	7x42	5.13179	Yes	Yes	1	7	8
626	7x42	Lig	5.73429	Yes	Yes	1	8	0
627	7x45	7x49	7.07059	No	Yes	0	9	9
628	7x52	7x53	3.60845	Yes	Yes	1	8	9
629	7x54	8x50	8.94893	No	Yes	0	9	8
630	7x54	8x54	2.65619	No	Yes	0	9	8
631	7x55	7x56	3.3256	Yes	No	0	7	8
632	8x47	8x49	5.58274	No	No	0	9	8
633	8x47	8x50	5.33024	No	Yes	0	9	8
634	G.HN.40	b.b5x3	3.4425	No	Yes	0	7	9
635	G.S1.01	G.S3.04	6.86274	No	Yes	0	6	6
636	G.H1.05	G.S2.04	2.3606	No	Yes	0	7	7
637	G.H1.07	G.H5.03	5.42143	No	No	0	9	8
638	G.S2.01	G.h2s4.01	2.36107	No	Yes	2	9	9
639	G.H2.06	b.l15x1	4.11976	Yes	Yes	2	9	7
640	G.H2.06	b.b18x1	2.9	Yes	No	2	9	9
641	G.H2.07	b.l7x2	3.41833	Yes	Yes	2	9	9
642	G.H3.17	G.h2s4.02	6.66262	Yes	No	0	4	7
643	G.S4.05	G.S5.07	2.77476	No	Yes	0	7	9
644	G.S4.07	G.s5hg.01	5.17917	No	Yes	0	8	9
645	G.HG.04	G.s4h3.04	2.73798	Yes	Yes	0	8	8
646	G.H3.03	G.hgh4.01	3.54655	No	No	9	4	4
647	G.H3.09	G.H3.13	3.29226	Yes	No	6	9	5
648	G.S5.05	G.s6h5.01	3.13393	Yes	Yes	13	9	9
649	G.HG.04	G.HG.08	4.29202	Yes	No	0	8	7
650	G.H4.03	G.HG.04	3.49952	Yes	Yes	0	3	8
651	G.hgh4.01	G.hgh4.02	6.8006	No	Yes	9	4	8
652	G.hgh4.03	G.hgh4.04	4.65988	No	No	0	6	5
653	G.H4.10	G.hgh4.04	2.52381	Yes	No	9	6	5
654	G.H4.02	G.H4.05	2.89298	No	No	0	5	4
655	G.H4.07	G.S6.05	2.415	No	No	0	4	5
656	G.H4.16	G.S6.01	4.19679	Yes	No	0	3	5
657	G.H5.14	G.S6.02	5.39881	No	Yes	0	6	8
658	G.s6h5.01	G.s6h5.05	4.11226	Yes	No	0	9	9
659	G.H5.03	G.s6h5.01	7.31298	No	Yes	13	8	9
660	5x68	G.H5.13	6.09548	No	No	0	7	7
661	b.1x13	b.1x9	3.57345	No	Yes	0	1	4
662	b.1x11	g.h1x11	4.61619	Yes	No	0	8	9
663	b.1x16	b.1x17	3.55845	No	No	0	4	2
664	b.1x19	b.b21x1	7.75559	Yes	Yes	4	6	7
665	b.b21x2	b.lh12x1	3.61167	Yes	No	0	6	3
666	b.lh12x2	g.l1x6	7.81833	No	No	24	8	4
667	b.l22x5	b.lhb1x3	2.58048	Yes	Yes	0	9	2
668	b.l24x3	b.lhb1x3	3.82488	Yes	Yes	0	5	2
669	b.b1x1	b.lhb1x10	3.05905	No	No	0	5	4
670	b.l1x3	b.l3x2	5.85	Yes	Yes	3	9	9
671	b.b2x1	b.l28x1	6.44309	Yes	Yes	2	8	9
672	b.b2x2	b.b6x3	2.49524	No	No	0	7	8
673	b.b2x3	b.b3x2	3.07905	No	No	3	6	5
674	b.b3x1	b.l2x3	5.04131	No	No	0	5	8
675	b.b7x4	b.l5x6	2.88905	Yes	No	11	8	9
676	b.b10x3	b.b6x2	4.225	No	No	0	8	8
677	b.b8x1	b.b9x4	3.75905	Yes	No	0	8	9
678	b.b8x2	b.b8x4	3.99881	No	Yes	0	8	6
679	b.b8x5	b.l8x3	3.96893	No	Yes	0	4	3
680	b.l8x4	b.l8x5	2.39548	No	Yes	0	3	3
681	b.b10x2	b.b10x4	2.67107	No	No	0	6	6
682	b.b12x7	b.l10x4	5.41821	No	No	22	9	3
683	b.b12x3	b.l13x7	3.04893	No	No	0	8	9
684	b.b12x5	b.b13x5	2.94738	No	No	5	6	4
685	b.b13x3	b.b13x6	4.35202	No	No	0	4	4
686	b.l13x3	b.l15x2	5.28	Yes	Yes	5	9	9
687	b.l14x1	b.l14x3	2.70179	No	No	0	4	5
688	b.b16x7	b.l14x6	2.55238	No	No	0	9	3
689	b.l16x2	b.l16x3	4.1944	No	Yes	0	9	3
690	b.b17x5	g.l1x2	2.92417	Yes	No	0	7	2
691	b.l17x3	b.l19x2	4.815	Yes	Yes	4	9	9
692	b.b18x1	b.l17x6	3.23893	No	Yes	2	9	9
693	b.l17x6	b.l19x1	7.96798	Yes	No	2	9	9
694	b.l18x1	b.l18x3	4.87833	Yes	No	7	6	5
695	b.b22x5	b.l18x2	2.81964	Yes	Yes	7	7	7
696	b.l18x2	b.l22x4	3.23833	Yes	No	7	7	9
697	b.l18x3	g.h2x11	6.53417	No	Yes	7	5	6
698	b.l18x5	b.l20x2	7.07393	No	No	0	2	9
699	b.b19x3	b.b23x2	2.44012	No	No	7	4	6
700	b.b20x2	b.l21x1	4.13333	No	No	0	6	2
701	b.l20x2	g.h2x7	4.4681	No	No	0	9	5
702	b.b21x1	g.l1x4	7.1194	Yes	Yes	4	7	8
703	b.b21x2	g.h2x1	3.85595	Yes	No	0	6	8
704	b.l21x7	b.l23x1	3.83262	No	Yes	0	5	6
705	b.l21x8	b.l23x1	2.47524	No	Yes	0	4	6
706	b.b22x1	b.b22x2	3.18095	No	No	0	8	8
707	b.b22x1	b.l23x1	3.18583	No	Yes	0	8	6
708	b.b23x1	b.l22x1	2.67988	Yes	No	0	5	9
709	b.l22x2	g.ctx3	2.86667	No	Yes	0	1	9
710	b.b23x6	b.l23x2	3.84702	Yes	No	0	7	8
711	b.b27x5	b.l25x7	2.38452	No	No	8	9	7
712	b.b26x1	b.b26x2	2.80524	No	No	0	9	7
713	g.ctx10	g.ctx13	2.56405	No	No	0	5	5
714	1x54	2x44	2.91286	No	No	0	8	7
715	1x60	I1x49	3.72476	No	No	0	8	7
716	2x42	3x45	2.93226	Yes	No	0	8	8
717	2x42	3x49	4.91905	Yes	Yes	0	8	9
718	2x46	2x50	3.43845	Yes	Yes	1	9	9
719	2x60	7x42	3.47405	Yes	Yes	1	8	8
720	3x28	E1x50	4.71643	Yes	Yes	0	7	8
721	3x37	4x57	3.24	Yes	Yes	1	8	8
722	3x37	5x461	2.83631	Yes	No	0	8	0
723	3x40	5x50	2.87143	No	No	0	9	6
724	3x41	4x52	3.00583	Yes	No	0	7	7
725	3x42	4x50	2.71667	Yes	Yes	1	8	9
726	3x44	5x53	3.07845	No	No	0	7	5
727	3x46	7x53	5.78607	No	Yes	1	9	9
728	3x47	5x57	3.34345	No	Yes	0	9	5
729	3x50	5x58	5.22452	Yes	Yes	0	9	8
730	3x50	7x53	5.11774	Yes	Yes	1	9	9
731	3x51	3x52	4.31393	Yes	Yes	0	8	6
732	3x51	5x57	6.49	Yes	Yes	0	8	5
733	3x51	5x60	6.94095	Yes	No	0	8	4
734	3x54	5x61	2.51036	No	No	0	8	7
735	4x60	5x39	3.51024	No	Yes	0	8	5
736	E2	E2x52	4.95167	Yes	No	1	7	7
737	5x39	E2	5.63655	Yes	Yes	1	5	7
738	5x36	5x38	2.59048	Yes	No	0	5	5
739	5x36	5x39	5.65417	Yes	Yes	1	5	5
740	5x39	5x43	5.05679	Yes	No	1	5	7
741	5x40	6x55	2.55286	No	No	0	8	8
742	5x43	Lig	3.90476	No	Yes	1	7	0
743	5x47	5x48	6.56595	Yes	Yes	1	8	9
744	5x47	6x44	4.19905	Yes	Yes	1	8	9
745	5x47	6x48	4.73595	Yes	Yes	1	8	9
746	5x47	6x49	4.10929	Yes	Yes	0	8	7
747	5x49	5x50	3.035	No	No	0	7	6
748	5x51	6x44	3.82155	No	Yes	1	9	9
749	5x54	6x44	3.01298	No	Yes	0	8	9
750	5x58	5x61	2.49202	Yes	No	0	8	7
751	5x58	6x37	6.31083	Yes	No	0	8	8
752	5x58	6x40	4.25286	Yes	No	0	8	8
753	5x58	6x41	2.75845	Yes	No	0	8	7
754	5x62	5x66	3.81405	No	No	0	9	8
755	5x62	6x34	4.82202	No	No	0	9	8
756	5x62	6x37	2.36536	No	No	0	9	8
757	5x65	6x33	4.29488	No	No	0	7	8
758	5x66	6x30	7.58476	No	No	0	8	9
759	6x40	7x52	2.49714	No	Yes	1	8	8
760	6x58	E3	3.33845	No	Yes	1	5	5
761	G.S1.02	G.S1.04	2.44786	Yes	No	0	4	7
762	G.H5.11	G.S1.02	3.1675	No	Yes	18	8	4
763	G.H1.01	G.S3.07	7.71798	Yes	Yes	19	9	9
764	G.H1.01	G.S4.05	2.44369	Yes	No	0	9	7
765	G.H5.05	G.s2s3.01	3.18095	Yes	Yes	14	5	4
766	G.s3h2.03	b.l7x2	3.83167	Yes	Yes	2	9	9
767	G.H2.08	G.H3.18	2.70548	No	Yes	0	8	9
768	G.s4h3.02	G.s5hg.01	2.87786	No	Yes	20	9	9
769	G.s4h3.04	G.s4h3.05	2.43071	Yes	Yes	0	8	8
770	G.H3.09	G.h4s6.01	2.62762	Yes	Yes	0	9	4
771	G.H3.15	G.H3.17	4.02702	No	Yes	0	8	4
772	G.H4.03	G.HG.01	5.51548	Yes	No	0	3	5
773	G.h4s6.08	G.h4s6.11	3.49714	No	No	0	5	8
774	G.H5.05	G.H5.08	2.90048	Yes	Yes	14	5	8
775	G.H5.08	G.H5.12	3.96833	Yes	No	0	8	7
776	5x65	G.H5.20	2.56714	No	No	0	7	8
777	6x37	G.H5.25	3.16262	No	No	0	8	6
778	b.1x4	g.h1x4	2.58857	Yes	No	0	8	5
779	b.lh12x2	g.h2x2	6.46774	No	No	24	8	9
780	b.b21x4	b.h2x1	2.93202	Yes	Yes	0	5	5
781	b.h2x5	b.lhb1x3	3.18476	Yes	Yes	0	5	2
782	b.b19x4	b.l17x3	5.60714	Yes	Yes	4	8	9
783	b.l25x5	b.l28x1	5.91905	No	Yes	0	7	9
784	g.ctx2	g.h2x15	2.81238	No	No	0	3	6
785	1x43	2x57	3.05083	No	Yes	0	7	8
786	1x43	2x58	3.39631	No	No	0	7	9
787	2x38	4x39	2.7219	No	No	0	7	6
788	2x50	3x39	2.50595	Yes	No	0	9	9
789	2x60	7x38	3.31548	Yes	Yes	1	8	7
790	2x64	7x39	3.58655	No	Yes	0	7	7
791	3x45	4x45	2.70095	No	No	0	8	7
792	3x48	5x53	2.53345	No	No	26	7	5
793	3x48	5x57	3.12048	No	Yes	26	7	5
794	5x40	6x59	2.89	No	No	0	8	7
795	5x41	6x56	2.69881	No	No	0	7	7
796	5x44	5x48	2.61881	No	Yes	1	9	9
797	5x44	6x52	3.51952	No	Yes	1	9	8
798	5x45	5x48	4.23298	No	Yes	0	7	9
799	5x47	5x51	4.32643	Yes	No	1	8	9
800	5x48	6x56	3.58774	Yes	No	0	9	7
801	6x52	Lig	4.72821	Yes	Yes	1	8	0
802	6x58	7x34	2.50714	No	No	1	5	6
803	7x34	E3	3.53869	No	Yes	1	6	5
804	7x30	7x33	3.42988	No	No	0	7	7
805	7x47	7x48	2.66548	Yes	No	0	8	7
806	G.H3.01	G.s1h1.03	3.04809	Yes	No	0	8	7
807	G.H3.02	G.H4.11	3.21083	No	No	0	6	8
808	b.l5x4	b.l5x5	4.28036	No	Yes	0	8	9
809	b.b25x3	b.l21x2	4.37869	No	Yes	0	5	4
810	1x39	7x39	5.18036	No	Yes	0	5	7
811	2x50	7x49	6.22059	Yes	Yes	1	9	9
812	E1x50	E1x51	2.75619	Yes	Yes	1	8	5
813	3x29	E2x52	3.96988	No	No	0	7	7
814	3x41	5x50	3.6594	Yes	No	0	7	6
815	3x56	I2x52	4.07679	No	No	0	7	6
816	E2	E2x51	8.23893	Yes	No	0	7	4
817	6x51	7x34	3.0631	Yes	No	1	8	6
818	g.h1x5	g.h1x9	9.09679	No	No	0	6	6
819	8x52	8x55	5.3569	No	No	0	6	6
820	G.H2.03	G.H2.06	2.71607	No	Yes	2	9	9
821	G.H2.03	b.l13x6	2.94048	No	Yes	2	9	9
822	G.H3.02	G.hgh4.01	2.73857	No	No	0	6	4
823	b.1x2	b.1x5	2.56274	Yes	No	0	0	3
824	G.H1.08	G.S2.04	3.58524	No	Yes	0	8	7
825	G.HG.14	G.HG.16	2.85333	No	No	0	5	4
826	b.b17x4	b.l16x3	3.98679	No	Yes	23	5	3
827	b.l21x2	b.l21x3	2.47583	Yes	No	0	4	3
828	E2	E2	9.52155	Yes	Yes	1	7	7
829	I1x48	b.l25x4	3.97167	No	No	0	8	5
830	2x63	E2	3.97083	No	Yes	1	8	7
831	3x22	E2	5.14833	No	Yes	1	4	7
832	3x33	E2x52	2.69333	No	No	1	8	7
833	4x56	4x57	3.41667	No	Yes	0	8	8
834	4x57	5x43	2.83	Yes	No	1	8	7
835	4x57	Lig	5.00833	Yes	Yes	1	8	0
836	4x64	4x68	4.69833	No	No	0	0	0
837	4x64	E2	6.27667	No	Yes	1	0	7
838	4x65	4x66	4.685	No	No	0	0	0
839	4x65	E2	4.04333	No	Yes	1	0	7
840	6x29	G.H5.13	3.375	No	No	0	8	7
841	G.H1.11	G.S2.05	2.8725	No	Yes	0	0	3
842	G.HG.15	G.s4h3.04	4.2	No	Yes	0	7	8
843	b.1x2	b.ntx3	3.82333	Yes	No	0	0	0
844	b.1x4	b.1x8	3.295	Yes	No	0	8	5
845	g.h1x12	g.l1x1	5.0125	No	No	0	6	1
846	b.b1x3	g.ctx17	2.57667	Yes	No	0	7	7
847	1x59	8x57	2.8625	No	No	0	7	8
848	3x49	4x38	2.68	Yes	No	12	9	8
849	4x38	I2x53	3.1725	No	Yes	12	8	9
850	b.b7x4	b.b7x5	2.35667	Yes	No	0	8	9
851	6x31	6x35	2.3531	No	No	0	7	7
852	E1x49	E1x51	2.33548	No	Yes	0	5	5
853	1x29	1x30	2.335	No	No	0	0	4
854	3x34	4x54	2.33452	No	No	0	7	7
855	G.H4.03	G.HG.05	2.32893	Yes	No	0	3	4
856	b.1x19	b.b21x2	2.30786	Yes	Yes	0	6	6
857	b.b27x4	b.b28x3	2.30036	No	Yes	0	5	7
858	5x41	6x60	2.29571	No	No	0	7	5
859	G.HN.45	G.HN.49	2.28214	No	No	0	4	4
860	b.b13x1	b.l12x3	2.275	No	No	0	4	5
861	3x53	G.H5.23	2.27429	No	No	0	9	4
862	G.HG.13	G.HG.14	2.26738	No	No	0	6	5
863	g.h2x14	g.h2x15	2.24714	No	No	0	4	6
864	G.S5.07	G.s1h1.06	2.24143	Yes	No	0	9	9
865	3x26	4x63	2.23333	Yes	No	0	7	0
866	G.HG.13	G.s4h3.04	2.22583	No	Yes	0	6	8
867	b.b9x2	b.l12x1	2.225	No	No	0	5	6
868	b.l22x2	b.l27x4	2.21952	No	No	0	1	9
869	b.1x1	b.1x2	2.21917	No	Yes	0	0	0
870	b.b18x4	b.b22x5	2.21143	No	Yes	0	3	7
871	b.l7x5	b.l9x1	2.20298	No	No	0	6	5
872	b.b24x2	b.l25x1	2.19607	No	No	0	5	3
873	G.hfs2.06	b.l7x4	2.19262	No	Yes	0	8	9
874	5x69	G.H5.09	2.19167	No	No	0	8	4
875	b.h2x4	b.h2x5	2.18952	No	Yes	0	3	5
876	8x48	8x52	2.17905	No	No	0	6	6
877	b.1x2	b.1x3	2.1775	Yes	No	0	0	1
878	b.b12x2	b.l13x1	2.1681	No	No	0	7	2
879	b.b16x3	b.b19x2	2.16214	No	Yes	0	6	6
880	2x55	2x551	2.1594	No	No	0	6	7
881	2x43	8x50	2.15536	No	Yes	0	8	8
882	b.1x12	b.1x9	2.15357	No	Yes	0	6	4
883	b.1x10	b.1x14	2.14857	No	No	0	1	4
884	4x41	I2x53	2.13262	No	Yes	0	8	9
885	6x36	G.H5.25	2.12571	No	No	0	8	6
886	2x551	3x31	2.12286	No	No	0	7	7
887	G.s3h2.01	G.s3h2.02	2.11	No	No	0	9	9
888	b.lhb1x1	b.lhb1x2	2.1081	No	No	0	1	1
889	1x32	2x65	2.09583	No	Yes	0	4	7
890	1x56	8x53	2.05286	No	No	0	9	8
891	G.H5.19	I2x50	2.04726	No	No	0	8	9
892	b.1x11	b.1x15	2.0431	Yes	No	0	8	7
893	1x53	2x47	2.01869	No	No	0	9	9
894	G.H4.06	G.HG.04	2.01286	No	Yes	0	7	8
895	g.h1x11	g.h1x7	2.00976	No	No	0	9	2
896	b.b12x1	b.l13x5	1.99333	No	No	0	6	5
897	G.HN.44	G.HN.48	1.99286	No	No	0	6	4
898	b.b18x4	b.b22x3	1.99286	No	No	0	3	6
899	I2x54	I2x55	1.965	No	No	0	7	6
900	G.S5.07	G.s5hg.01	1.93333	Yes	Yes	0	9	9
901	G.s1h1.03	G.s1h1.04	1.93321	No	No	0	7	8
902	6x35	6x39	1.92917	No	No	0	7	7
903	b.b21x4	g.h2x1	1.91571	Yes	No	0	5	8
904	G.HN.43	b.b5x6	1.91238	No	No	0	8	6
905	G.h2s4.02	G.h2s4.03	1.87262	No	No	0	7	5
906	b.l14x1	b.l14x2	1.87	No	No	0	4	4
907	b.1x7	g.h1x8	1.85417	No	No	0	8	7
908	G.HN.51	b.l1x4	1.8525	No	No	0	4	6
909	6x32	G.H5.26	1.83798	No	No	0	9	5
910	7x55	8x54	1.82667	Yes	Yes	0	7	8
911	6x61	E3	1.82	No	Yes	0	3	5
912	1x54	2x48	1.81833	No	No	0	8	7
913	g.h2x13	g.h2x9	1.805	No	No	0	1	4
914	b.1x15	g.h1x15	1.79774	No	No	0	7	8
915	G.S4.07	G.s4h3.03	1.775	No	No	0	8	0
916	b.l2x2	b.l6x2	1.75	No	No	0	1	6
917	G.HG.12	G.HG.13	1.74857	No	No	0	2	6
918	G.H1.09	G.S2.05	1.74667	No	Yes	0	7	3
919	b.1x4	b.1x7	1.74643	Yes	No	0	8	8
920	5x36	5x37	1.74167	Yes	No	0	5	6
921	b.b10x5	b.b6x4	1.73357	Yes	No	0	9	7
922	4x54	4x58	1.72643	No	No	0	7	6
923	b.lh12x3	g.h2x2	1.71	No	No	0	4	9
924	b.l1x5	b.l3x2	1.70714	No	Yes	0	7	9
925	1x36	2x65	1.70357	No	Yes	0	6	7
926	1x45	7x47	1.67476	No	Yes	0	5	8
927	1x34	1x38	1.67024	No	No	0	3	5
928	b.1x6	b.1x9	1.6694	No	Yes	0	3	4
929	7x55	8x51	1.6681	Yes	No	0	7	9
930	6x39	7x52	1.6644	No	Yes	0	7	8
931	G.S1.04	G.S4.01	1.65476	No	No	0	7	8
932	4x41	I2x56	1.65238	No	No	0	8	6
933	3x31	3x35	1.64024	No	No	0	7	7
934	2x41	4x43	1.62679	No	No	0	8	6
935	b.l13x1	b.l13x2	1.625	No	No	0	2	6
936	8x56	b.l25x4	1.62048	No	No	0	7	5
937	3x26	4x62	1.58333	Yes	No	0	7	5
938	g.h1x6	g.h1x9	1.575	No	No	0	4	6
939	b.b28x6	b.l25x2	1.5731	Yes	No	0	9	5
940	5x68	G.H5.17	1.56417	No	No	0	7	5
941	2x66	2x67	1.54167	No	No	0	7	6
942	1x47	2x55	1.54048	No	No	0	7	6
943	7x51	7x55	1.52107	No	Yes	0	7	7
944	b.b25x4	b.lhb1x6	1.51702	No	Yes	0	4	3
945	G.HN.11	G.HN.34	1.51405	No	No	0	3	3
946	1x55	1x59	1.51381	No	No	0	7	7
947	1x44	1x48	1.51024	No	No	0	6	5
948	6x50	7x40	1.50333	No	No	0	9	8
949	G.hns1.03	I2x52	1.50167	No	No	0	4	6
950	G.s6h5.02	G.s6h5.04	1.48881	No	No	0	7	8
951	1x48	1x52	1.47714	No	No	0	5	8
952	3x26	4x61	1.46869	Yes	No	0	7	7
953	I2x53	I2x54	1.46714	Yes	No	0	9	7
954	1x40	1x43	1.42619	No	No	0	6	7
955	G.H3.05	G.s1h1.02	1.425	No	No	0	9	7
956	g.h1x12	g.h1x9	1.41429	No	No	0	6	6
957	b.b21x5	b.h2x2	1.405	Yes	No	0	4	1
958	g.ctx6	g.ctx7	1.40214	Yes	No	0	6	4
959	3x21	3x23	1.38429	No	No	0	7	5
960	G.HG.06	G.HG.09	1.38214	No	No	0	5	1
961	g.h1x10	g.h1x13	1.37619	No	No	0	9	1
962	b.l24x3	b.lhb1x5	1.37476	Yes	No	0	5	1
963	b.1x10	b.1x7	1.36738	No	No	0	1	8
964	1x42	7x47	1.3419	No	Yes	0	7	8
965	G.HG.03	G.HG.06	1.3269	Yes	No	0	6	5
966	b.b16x1	b.l17x3	1.32095	No	Yes	0	4	9
967	G.S1.03	G.h2s4.04	1.32095	No	No	0	9	9
968	5x67	6x29	1.31833	No	No	0	8	8
969	6x41	6x42	1.31667	No	No	0	7	7
970	b.b7x1	b.b9x1	1.31631	Yes	No	0	4	4
971	b.1x5	b.1x9	1.31524	No	Yes	0	3	4
972	5x59	5x63	1.31476	No	No	0	9	8
973	3x30	4x62	1.31333	No	No	0	8	5
974	7x36	7x40	1.31083	No	No	0	6	8
975	7x43	7x48	1.29726	No	No	0	7	7
976	b.b24x5	b.b25x5	1.29238	No	No	0	5	4
977	5x56	5x60	1.29071	No	No	0	6	4
978	b.lhb1x6	b.lhb1x7	1.27048	Yes	No	0	3	1
979	G.HG.16	G.HG.17	1.26667	No	No	0	4	3
980	G.H3.01	G.H3.04	1.25917	Yes	No	0	8	9
981	1x35	2x65	1.24833	No	Yes	0	6	7
982	3x25	3x26	1.24381	No	Yes	0	9	7
983	b.b20x1	b.l21x5	1.23429	No	No	0	5	4
984	6x28	6x31	1.23167	No	No	0	5	7
985	6x27	6x31	1.22369	No	No	0	6	7
986	G.H2.04	G.H3.11	1.19214	No	No	0	9	7
987	b.b22x5	b.l24x1	1.19095	Yes	No	0	7	5
988	1x58	2x44	1.18143	No	No	0	6	7
989	b.l13x5	b.l15x2	1.17869	No	Yes	0	5	9
990	8x48	8x51	1.16524	No	No	0	6	9
991	G.H3.04	G.H3.07	1.15952	No	No	0	9	5
992	7x30	7x32	1.14833	No	No	0	7	5
993	b.lh12x2	g.h2x1	1.14714	No	No	0	8	8
994	3x54	5x64	1.14036	No	No	0	8	6
995	g.ctx11	g.ctx17	1.13571	No	No	0	4	7
996	b.l8x3	b.l8x6	1.12667	Yes	No	0	3	4
997	b.b16x2	b.l17x1	1.12381	No	No	0	5	2
998	5x60	5x63	1.12143	No	No	0	4	8
999	1x34	1x37	1.11429	No	No	0	3	5
1000	g.l1x3	g.l1x5	1.1	No	No	0	1	4
1001	b.lhb1x2	b.lhb1x3	1.07964	No	Yes	0	1	2
1002	3x21	3x22	1.06333	No	No	0	7	4
1003	5x45	5x46	1.06286	No	No	0	7	6
1004	G.S3.07	G.s3h2.01	1.06	Yes	No	0	9	9
1005	G.HN.10	G.HN.37	1.05833	No	No	0	3	2
1006	G.H5.01	G.H5.02	1.04452	No	No	0	8	4
1007	G.HN.41	G.HN.45	1.02607	No	No	0	4	4
1008	6x42	6x46	1.02429	No	No	0	7	5
1009	6x26	6x27	1.00536	No	No	0	5	6
1010	G.s4h3.05	G.s4h3.06	0.994286	Yes	No	0	8	0
1011	G.H2.01	G.s1h1.03	0.9925	No	No	0	9	7
1012	2x61	2x65	0.989643	No	Yes	0	8	7
1013	G.HN.52	G.hns1.03	0.968333	No	No	0	4	4
1014	1x47	1x51	0.930357	No	No	0	7	6
1015	6x34	6x38	0.923333	No	No	0	8	7
1016	3x27	4x62	0.921667	No	No	0	6	5
1017	1x41	1x45	0.874286	No	No	0	5	5
1018	g.h1x3	g.h1x6	0.87131	No	No	0	3	4
1019	7x31	7x32	0.862381	No	No	0	4	5
1020	4x44	4x48	0.859405	No	No	0	3	5
1021	8x47	G.H5.24	0.848333	No	No	0	9	8
1022	2x63	E1	0.846667	No	No	0	8	0
1023	1x26	1x31	0.845	No	Yes	0	0	5
1024	2x62	E1x51	0.834643	No	Yes	0	7	5
1025	G.hns1.02	I2x55	0.828333	No	No	0	4	6
1026	1x28	1x31	0.823333	No	Yes	0	0	5
1027	G.HN.36	b.b5x2	0.798571	No	Yes	0	4	7
1028	5x52	5x56	0.783809	No	No	0	7	6
1029	b.l17x1	b.l17x2	0.78	No	No	0	2	6
1030	G.HN.11	G.HN.32	0.773333	No	No	0	3	5
1031	G.H1.02	G.H1.03	0.761905	No	No	0	9	9
1032	G.H1.10	G.S2.04	0.76	No	Yes	0	0	7
1033	1x55	8x54	0.754286	No	Yes	0	7	8
1034	G.H1.06	G.H5.01	0.750833	No	No	0	9	8
1035	b.1x1	g.ntx3	0.75	No	No	0	0	0
1036	1x38	1x42	0.734167	No	No	0	5	7
1037	g.h1x2	g.h1x5	0.723333	No	No	0	2	6
1038	1x32	1x33	0.716667	No	No	0	4	5
1039	1x30	1x32	0.704762	No	No	0	4	4
1040	G.HN.31	G.HN.34	0.674881	No	No	0	3	3
1041	G.hfs2.05	G.hfs2.06	0.672857	No	No	0	9	8
1042	4x51	4x55	0.656429	No	No	0	5	6
1043	5x41	5x42	0.650476	No	No	0	7	7
1044	G.H1.03	G.s6h5.03	0.64	No	No	0	9	9
1045	G.H5.21	G.H5.22	0.607143	Yes	No	0	4	4
1046	G.HN.45	G.HN.46	0.6	No	No	0	4	4
1047	1x31	1x35	0.59881	Yes	No	0	5	6
1048	g.ctx6	g.h2x16	0.583095	Yes	No	0	6	4
1049	G.HN.10	G.HN.34	0.561429	No	No	0	3	3
1050	2x45	4x48	0.538095	Yes	No	0	9	5
1051	G.HN.28	G.HN.30	0.533333	No	No	0	0	8
1052	8x58	8x59	0.529048	No	No	0	8	6
1053	1x52	8x58	0.527143	No	No	0	8	8
1054	b.1x21	b.b21x2	0.508333	No	Yes	0	3	6
1055	b.1x17	b.1x20	0.494167	No	No	0	2	2
1056	5x69	5x70	0.479167	No	No	0	8	5
1057	G.s2s3.01	G.s2s3.02	0.466667	Yes	No	0	4	4
1058	G.HN.49	G.HN.53	0.445714	No	No	0	4	2
1059	4x52	4x55	0.438571	No	No	0	7	6
1060	G.s4h3.08	G.s4h3.14	0.420952	No	No	0	0	0
1061	4x63	4x67	0.418333	No	No	0	0	0
1062	g.h1x3	g.ntx1	0.412381	No	No	0	3	0
1063	G.H3.01	G.s4h3.08	0.404762	Yes	No	0	8	0
1064	G.HN.51	G.hns1.01	0.371429	No	No	0	4	3
1065	6x25	6x26	0.325	No	No	0	4	5
1066	G.hgh4.06	G.hgh4.07	0.303333	No	No	0	2	8
1067	G.s4h3.13	G.s4h3.14	0.299048	No	No	0	0	0
1068	4x69	E2	0.29	No	Yes	0	0	7
1069	6x23	6x26	0.285714	No	No	0	0	5
1070	b.h2x4	g.h2x6	0.27	No	No	0	3	2
1071	g.h2x10	g.h2x13	0.251667	No	No	0	3	1
1072	b.1x1	g.ntx2	0.25	No	No	0	0	0
1073	G.H3.04	G.s4h3.07	0.238333	No	No	0	9	0
1074	b.lh12x5	g.h2x5	0.225238	No	No	0	0	6
1075	G.HN.38	G.HN.41	0.225	No	No	0	3	4
1076	b.1x4	b.ntx2	0.220833	Yes	No	0	8	0
1077	4x47	4x51	0.22	No	No	0	5	5
1078	6x24	6x25	0.214286	No	No	0	6	4
1079	6x22	G.h4s6.03	0.202857	No	No	0	0	4
1080	G.HN.35	G.HN.38	0.197738	No	No	0	3	3
1081	1x27	1x31	0.186667	No	Yes	0	0	5
1082	G.H4.13	G.H4.16	0.14381	No	Yes	0	2	3
1083	G.HN.38	G.HN.42	0.0719048	No	No	0	3	4

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	G.S1.02	4.31637	4	18	4
2	G.S1.06	3.83812	4	19	8
3	G.H1.01	4.06188	5	19	9
4	G.S2.04	2.54039	4	0	7
5	G.S2.05	3.99949	4	0	3
6	G.S2.08	7.16027	4	14	5
7	G.s2s3.01	5.4867	4	14	4
8	G.S3.03	6.6761	4	18	7
9	G.S3.04	6.89973	4	2	6
10	G.S3.06	7.31	5	2	6
11	G.S3.07	3.45601	4	19	9
12	G.s3h2.03	5.16667	4	2	9
13	G.H2.06	4.73519	7	2	9
14	G.H2.07	5.12798	6	2	9
15	G.H2.09	5.0883	4	2	8
16	G.h2s4.01	5.1519	5	2	9
17	G.S4.03	2.96437	4	0	7
18	G.S4.06	4.04768	4	0	7
19	G.s4h3.05	3.43946	4	0	8
20	G.s4h3.04	3.54421	5	0	8
21	G.H3.01	3.07259	4	0	8
22	G.H3.09	5.54714	6	6	9
23	G.H3.17	5.37493	5	0	4
24	G.H3.18	4.93354	4	0	9
25	G.S5.04	3.44997	4	6	9
26	G.S5.05	3.66214	6	13	9
27	G.S5.06	4.17952	4	0	8
28	G.S5.07	2.57699	4	0	9
29	G.s5hg.01	3.24036	4	20	9
30	G.HG.03	2.72426	4	20	6
31	G.HG.04	4.04533	5	0	8
32	G.hgh4.02	3.67724	5	9	8
33	G.hgh4.05	6.00086	4	0	6
34	G.H4.03	5.0469	4	0	3
35	G.H4.10	5.96619	4	9	6
36	G.H4.15	6.24208	4	6	8
37	G.H4.16	3.63434	4	6	3
38	G.h4s6.01	5.86086	4	0	4
39	G.S6.02	6.60173	4	0	8
40	G.s6h5.01	4.37583	5	13	9
41	G.H5.05	4.34774	4	14	5
42	G.H5.08	4.92581	5	14	8
43	G.H5.21	4.45649	4	0	4
44	b.1x4	1.96271	4	0	8
45	b.1x9	2.17792	4	0	4
46	b.1x11	3.53613	4	0	8
47	b.1x19	4.11155	4	4	6
48	b.h2x1	3.49506	4	0	5
49	b.h2x5	2.77707	5	0	5
50	b.lhb1x3	2.66744	4	0	2
51	b.lhb1x6	3.93604	4	10	3
52	b.b1x3	3.76494	4	3	7
53	b.l1x3	8.59964	5	3	9
54	b.b2x1	7.4239	5	2	8
55	b.b2x5	5.687	6	3	7
56	b.l3x2	4.91676	5	3	9
57	b.b4x3	4.02557	4	11	7
58	b.b4x4	7.39402	4	3	8
59	b.b4x5	3.97485	4	17	7
60	b.b4x6	10.1818	5	3	9
61	b.l4x2	10.6282	4	3	4
62	b.b5x2	5.06887	4	0	7
63	b.b5x3	5.50159	6	3	9
64	b.b5x5	4.6597	4	17	5
65	b.b5x7	5.11301	4	0	7
66	b.l5x1	3.88686	5	11	8
67	b.l5x5	6.70508	6	2	9
68	b.b6x5	3.70679	6	0	6
69	b.l6x5	5.61405	4	15	4
70	b.b7x1	5.12829	5	15	4
71	b.b7x4	3.3186	5	11	8
72	b.l7x2	3.52815	4	2	9
73	b.l7x4	3.25042	4	0	9
74	b.b8x1	2.97348	4	2	8
75	b.b8x4	4.23331	6	11	6
76	b.l8x3	2.79929	4	21	3
77	b.l8x5	3.4092	4	21	3
78	b.l9x3	5.6576	7	2	9
79	b.l9x6	4.58142	9	2	8
80	b.b10x5	4.49131	5	0	9
81	b.l10x1	4.07485	4	0	3
82	b.b11x4	4.85819	5	2	9
83	b.l11x2	8.30911	4	2	9
84	b.b12x6	7.40299	7	2	8
85	b.b13x7	7.08698	5	5	7
86	b.l13x3	7.05099	6	5	9
87	b.l13x6	4.65295	5	2	9
88	b.b14x3	3.84765	4	5	5
89	b.b15x1	6.27555	5	5	9
90	b.b15x2	5.41702	4	4	6
91	b.l15x1	4.41027	4	2	7
92	b.l15x2	4.68538	5	5	9
93	b.b16x4	9.94435	4	5	6
94	b.b16x5	4.03768	4	0	5
95	b.b16x6	7.93196	6	5	8
96	b.l16x3	6.49607	4	23	3
97	b.b17x5	6.32473	4	4	7
98	b.b17x7	7.12488	4	4	8
99	b.l17x3	7.29399	6	4	9
100	b.l17x6	6.41988	4	2	9
101	b.b18x3	4.68952	4	4	8
102	b.b18x5	5.58952	4	4	5
103	b.l18x1	5.57252	7	7	6
104	b.l18x2	5.19443	4	7	7
105	b.b19x2	5.62865	6	4	6
106	b.b19x4	4.78018	4	4	8
107	b.l19x2	5.11326	5	4	9
108	b.b20x4	9.41357	5	4	8
109	b.b20x6	6.40805	5	4	6
110	b.b21x1	7.56681	4	4	7
111	b.b21x2	2.57095	4	0	6
112	b.b21x4	3.23554	4	0	5
113	b.b21x5	4.82637	4	0	4
114	b.b21x7	6.43945	5	0	5
115	b.l21x2	5.26399	4	0	4
116	b.b22x5	4.58694	6	7	7
117	b.l22x5	5.75425	6	10	9
118	b.b23x1	3.49467	4	0	5
119	b.b23x6	6.06853	6	16	7
120	b.l23x1	7.19485	4	0	6
121	b.b24x4	5.93696	4	16	6
122	b.b24x6	4.71298	4	16	8
123	b.l24x3	4.08976	4	0	5
124	b.l25x3	8.26819	5	8	9
125	b.l28x1	10.7664	6	2	9
126	b.l28x2	7.32601	4	8	9
127	b.b28x3	3.63702	4	0	7
128	b.b28x4	6.90354	4	8	6
129	b.b28x6	7.98038	5	8	9
130	g.l1x4	4.29424	5	4	8
131	g.h2x11	7.66437	4	7	6
132	g.ctx3	6.51124	5	0	9
133	g.ctx6	3.81748	5	0	6
134	g.ctx15	6.10899	4	3	9
135	g.ctx16	4.31568	8	3	8
136	1x31	0.613452	4	0	5
137	1x50	4.99371	5	0	9
138	I1x50	5.91571	4	25	9
139	2x42	3.69888	5	0	8
140	2x45	4.08307	4	1	9
141	2x46	3.67872	4	1	9
142	2x50	5.87731	5	1	9
143	2x57	3.58923	4	1	8
144	2x60	3.54298	4	1	8
145	2x65	1.50935	4	0	7
146	E1x50	5.12179	6	1	8
147	E1x51	2.1022	4	1	5
148	3x26	1.63229	4	0	7
149	3x28	5.03259	4	0	7
150	3x37	3.52033	5	1	8
151	3x41	3.30021	4	0	7
152	3x42	4.35321	4	1	8
153	3x43	4.00536	4	1	8
154	3x49	4.84764	5	12	9
155	3x50	5.62577	4	1	9
156	3x51	7.11432	4	0	8
157	3x52	5.65339	4	0	6
158	I2x53	5.76071	6	12	9
159	I2x57	6.10324	4	12	7
160	4x50	3.99923	4	1	9
161	4x57	4.01476	6	1	8
162	E2	5.73474	11	1	7
163	5x36	3.86726	4	1	5
164	5x39	4.96443	4	1	5
165	5x47	6.75722	6	1	8
166	5x48	3.89707	5	1	9
167	5x57	3.83271	4	26	5
168	5x58	4.31992	6	0	8
169	6x44	3.54902	5	1	9
170	6x48	5.56191	8	1	9
171	6x49	3.4053	4	0	7
172	6x51	6.12043	5	1	8
173	6x52	6.25276	6	1	8
174	E3	3.041	5	1	5
175	7x38	5.82244	4	1	7
176	7x39	4.3791	5	1	7
177	7x42	5.25469	7	1	8
178	7x47	2.56012	4	0	8
179	7x49	5.42976	4	1	9
180	7x52	2.69402	4	1	8
181	7x53	5.19383	5	1	9
182	7x55	2.08536	4	0	7
183	8x50	6.27788	5	25	8
184	8x54	3.212	5	0	8
185	Lig	6.70898	12	1	0
186	b.1x2	2.69568	4	0	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	b.b3x2	b.b4x6	14.2779	4.42048	No	Yes	3	5	9
2	b.b2x3	b.b3x2	13.3532	3.07905	No	No	3	6	5
3	b.b26x2	b.b2x3	29.8508	5.265	No	No	0	7	6
4	b.b26x1	b.b26x2	30.0681	2.80524	No	No	0	9	7
5	b.b26x1	b.l28x1	30.2875	5.58691	No	Yes	0	9	9
6	G.H2.09	b.l28x1	75.0417	4.40917	Yes	Yes	2	8	9
7	G.H2.09	G.H3.17	75.669	6.15631	Yes	Yes	0	8	4
8	G.H2.08	G.H3.17	38.2921	2.43679	No	Yes	0	8	4
9	G.H2.08	G.H3.18	38.3723	2.70548	No	Yes	0	8	9
10	G.H3.18	G.S4.02	76.8192	6.17583	Yes	No	0	9	7
11	G.S4.02	G.S5.02	100	3.52107	No	No	0	7	6
12	G.H3.09	G.S5.02	99.4169	4.63381	Yes	No	6	9	6
13	G.H3.09	G.S5.04	98.8807	4.06095	Yes	Yes	6	9	9
14	G.S5.04	G.S5.06	99.3108	2.66869	Yes	Yes	0	9	8
15	G.S5.06	G.s4h3.01	51.7423	7.06964	Yes	No	0	8	7
16	G.HG.04	G.s4h3.01	51.6942	7.68429	Yes	No	0	8	7
17	G.HG.04	G.s4h3.04	51.4228	2.73798	Yes	Yes	0	8	8
18	G.s4h3.04	G.s4h3.05	50.0519	2.43071	Yes	Yes	0	8	8
19	G.S4.07	G.s4h3.05	49.3622	2.75452	No	Yes	0	8	8
20	G.S4.07	G.s5hg.01	49.2463	5.17917	No	Yes	0	8	9
21	G.S5.07	G.s5hg.01	96.6679	1.93333	Yes	Yes	0	9	9
22	G.S5.07	G.s6h5.01	92.7251	3.35845	Yes	Yes	0	9	9
23	G.S5.05	G.s6h5.01	91.0618	3.13393	Yes	Yes	13	9	9
24	G.S4.03	G.S5.05	90.7604	2.45131	Yes	Yes	0	7	9
25	G.S1.04	G.S4.03	87.7656	3.19238	No	Yes	0	7	7
26	G.S1.02	G.S1.04	87.422	2.44786	Yes	No	0	4	7
27	G.H3.15	G.H3.17	38.2909	4.02702	No	Yes	0	8	4
28	G.H3.15	G.H3.18	38.3711	3.58071	No	Yes	0	8	9
29	G.S5.06	G.S6.05	48.3092	4.08845	Yes	No	0	8	5
30	G.HG.01	G.S6.05	48.2054	3.30857	No	No	0	5	5
31	G.HG.01	G.s6h5.02	47.9992	4.36774	No	No	0	5	7
32	G.HG.02	G.s6h5.02	47.8867	3.9825	No	No	0	9	7
33	G.HG.02	G.HG.03	47.8341	2.64964	No	Yes	0	9	6
34	G.HG.03	G.s5hg.01	47.5816	2.97107	Yes	Yes	20	6	9
35	G.S1.02	G.S3.03	86.8641	6.75762	Yes	Yes	18	4	7
36	G.S1.05	G.h2s4.01	23.1772	8.74298	No	Yes	0	9	9
37	G.S3.01	G.S3.03	86.7674	5.34964	No	Yes	0	4	7
38	G.H5.08	G.S3.01	86.594	3.37845	Yes	No	0	8	4
39	G.H2.07	G.h2s4.01	21.1367	2.65786	Yes	Yes	2	9	9
40	G.H5.08	G.H5.12	85.0262	3.96833	Yes	No	0	8	7
41	G.H5.12	I2x51	84.8507	3.20262	No	No	0	7	7
42	G.H5.15	I2x51	84.675	2.47536	No	No	0	8	7
43	G.H5.15	G.H5.19	84.4991	2.39655	No	No	0	8	8
44	3x53	G.H5.19	83.9702	5.015	No	No	0	9	8
45	5x58	6x37	11.4647	6.31083	Yes	No	0	8	8
46	3x50	5x58	19.0322	5.22452	Yes	Yes	0	9	8
47	3x50	G.H5.23	83.6166	7.1956	Yes	No	0	9	4
48	3x53	G.H5.23	83.7935	2.27429	No	No	0	9	4
49	b.l27x5	g.ctx4	14.2353	4.95048	No	No	0	5	7
50	g.ctx3	g.ctx4	14.033	3.7375	Yes	No	0	9	7
51	g.ctx3	g.ctx6	10.6592	8.73976	Yes	Yes	0	9	6
52	b.h2x1	b.h2x5	10.8671	3.35214	Yes	Yes	0	5	5
53	b.b21x4	g.h2x1	28.2005	1.91571	Yes	No	0	5	8
54	b.b21x2	g.h2x1	26.8047	3.85595	Yes	No	0	6	8
55	b.1x19	b.b21x2	25.9647	2.30786	Yes	Yes	0	6	6
56	b.1x15	b.1x19	10.5246	3.99595	No	Yes	0	7	6
57	b.l25x6	b.l28x1	49.2394	20.5381	No	Yes	0	8	9
58	b.l23x1	b.l25x6	49.0158	19.2857	Yes	No	0	6	8
59	b.b10x2	b.b10x4	10.2481	2.67107	No	No	0	6	6
60	b.b10x2	b.b6x2	14.4983	2.49476	No	No	0	6	8
61	b.b10x3	b.b6x2	14.573	4.225	No	No	0	8	8
62	b.b10x3	b.b11x4	14.5791	2.75631	No	Yes	2	8	9
63	b.b11x4	b.l9x3	14.0561	5.6431	Yes	Yes	2	9	9
64	b.b11x6	b.l9x3	19.3693	14.9948	No	Yes	2	9	9
65	b.l11x1	b.l9x6	20.2064	5.58893	No	Yes	2	9	8
66	b.1x19	b.b21x1	14.3831	7.75559	Yes	Yes	4	6	7
67	b.b17x7	b.b21x1	11.1701	4.40762	Yes	Yes	4	8	7
68	b.l21x7	b.l23x1	40.447	3.83262	No	Yes	0	5	6
69	b.l21x7	b.l23x2	40.2165	5.61155	No	No	0	5	8
70	b.b23x6	b.l23x2	39.2828	3.84702	Yes	No	0	7	8
71	b.b23x6	b.b24x6	36.3971	5.10941	Yes	Yes	16	7	8
72	b.b21x7	b.b24x6	36.1433	8.03798	Yes	Yes	0	5	8
73	b.b20x5	b.b21x4	23.6677	3.29536	No	Yes	0	7	5
74	7x42	Lig	10.1891	5.73429	Yes	Yes	1	8	0
75	6x48	Lig	30.2296	4.58667	Yes	Yes	1	9	0
76	6x44	6x48	34.0994	3.8031	Yes	Yes	1	9	9
77	3x43	6x44	41.6574	2.90845	Yes	Yes	1	8	9
78	3x43	7x53	60.9508	6.54381	Yes	Yes	1	8	9
79	3x50	7x53	61.058	5.11774	Yes	Yes	1	9	9
80	1x50	2x50	10.6584	9.82405	Yes	Yes	0	9	9
81	2x46	3x43	10.6095	3.11	Yes	Yes	1	9	8
82	b.b11x6	b.l11x1	20.1969	3.22548	No	No	2	9	9
83	G.H2.07	b.l9x6	19.9356	4.01929	Yes	Yes	2	9	8
84	G.S1.05	G.S4.02	23.3216	3.00702	No	No	0	9	7
85	b.b2x3	b.b2x5	16.303	3.97298	No	Yes	3	6	7
86	b.b20x5	b.b21x7	23.852	5.31631	No	Yes	0	7	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
2x56	3x32	7.93	1	No	No	8	8	2	1
2x56	7x42	4.24429	1	No	Yes	8	8	2	1
2x57	7x39	3.92238	1	Yes	Yes	8	7	2	2
2x57	7x42	4.78012	1	Yes	Yes	8	8	2	1
2x60	7x39	4.0744	1	Yes	Yes	8	7	2	2
3x32	7x42	7.66417	1	No	Yes	8	8	1	1
3x32	Lig	10.1232	1	No	Yes	8	0	1	0
3x33	4x57	6.39714	1	No	Yes	8	8	1	1
3x33	Lig	9.64226	1	No	Yes	8	0	1	0
3x34	4x53	2.45417	0	No	No	7	8	2	2
3x34	4x57	3.19643	0	No	Yes	7	8	2	1
3x36	6x48	3.56321	1	No	Yes	7	9	1	1
3x36	Lig	8.59143	1	No	Yes	7	0	1	0
3x37	3x41	3.91571	1	Yes	Yes	8	7	1	2
3x37	4x53	5.06464	1	Yes	No	8	8	1	2
3x37	Lig	2.545	1	Yes	Yes	8	0	1	0
3x40	6x48	7.3275	0	No	Yes	9	9	2	1
5x47	6x52	16.6067	1	Yes	Yes	8	8	2	1
5x48	6x52	2.47988	1	Yes	Yes	9	8	2	1
6x44	6x48	3.8031	1	Yes	Yes	9	9	2	1
6x48	6x52	5.30107	1	Yes	Yes	9	8	1	1
6x48	7x41	6.58167	1	Yes	No	9	8	1	2
6x48	7x45	8.59607	1	Yes	No	9	9	1	2
6x48	Lig	4.58667	1	Yes	Yes	9	0	1	0
6x51	6x52	4.88119	1	Yes	Yes	8	8	1	1
6x51	6x55	5.405	1	Yes	No	8	8	1	1
6x51	7x38	5.06238	1	Yes	Yes	8	7	1	1
6x51	Lig	12.1905	1	Yes	Yes	8	0	1	0
6x55	Lig	4.29536	1	No	Yes	8	0	1	0
7x38	7x42	5.75417	1	Yes	Yes	7	8	1	1
7x38	Lig	9.15774	1	Yes	Yes	7	0	1	0
7x39	7x42	5.13179	1	Yes	Yes	7	8	2	1
7x42	Lig	5.73429	1	Yes	Yes	8	0	1	0
2x60	7x42	3.47405	1	Yes	Yes	8	8	2	1
3x37	4x57	3.24	1	Yes	Yes	8	8	1	1
3x37	5x461	2.83631	1	Yes	No	8	0	1	2
5x39	5x43	5.05679	1	Yes	No	5	7	2	1
5x40	6x55	2.55286	0	No	No	8	8	2	1
5x43	Lig	3.90476	1	No	Yes	7	0	1	0
5x47	5x48	6.56595	1	Yes	Yes	8	9	2	2
5x47	6x44	4.19905	1	Yes	Yes	8	9	2	2
5x47	6x48	4.73595	1	Yes	Yes	8	9	2	1
2x60	7x38	3.31548	1	Yes	Yes	8	7	2	1
5x44	5x48	2.61881	1	No	Yes	9	9	2	2
5x44	6x52	3.51952	1	No	Yes	9	8	2	1
6x52	Lig	4.72821	1	Yes	Yes	8	0	1	0
6x51	7x34	3.0631	1	Yes	No	8	6	1	2
3x33	E2x52	2.69333	1	No	No	8	7	1	2
4x56	4x57	3.41667	0	No	Yes	8	8	2	1
4x57	5x43	2.83	1	Yes	No	8	7	1	1
4x57	Lig	5.00833	1	Yes	Yes	8	0	1	0

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
83.33	Single	8THL	Epinephrine	8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
80.00	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2
80.00	Single	8E9Y	PubChem 446603	8E9Y-M₃-PubChem 446603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
80.00	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
78.57	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
78.57	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
78.57	Single	7W6P	W96	7W6P-α_2a-W96-Go/&β;1/&γ;2
78.57	Single	7W7E	W58	7W7E-α_2a-W58-Go/&β;1/&γ;2
78.57	Consensus	5ht_off	Orthosteric Ligand	5ht2_off 5ht5_off 5ht1_off
78.57	Consensus	h1_off	Orthosteric Ligand	3RZE-H₁-Cidoxepin 8X5Y-H₁-Astemizole 8X63-H₁-Mepyramine 8X64-H₁-Desloratadine
78.57	Consensus	histamine_off	Orthosteric Ligand	h1_off
78.57	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
76.92	Single	3NY8	ICI 118-551	3NY8-β₂-ICI 118-551
76.92	Single	4GBR	(S)-Carazolol	4GBR-β₂-(S)-Carazolol
76.92	Single	6K42	Dexmedetomidine	6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
76.92	Single	6PS0	(S)-Carazolol	6PS0-β₂-(S)-Carazolol
76.92	Consensus	alpha2_on	Orthosteric Ligand	alpha2a_on alpha2b_on
76.92	Consensus	alpha_on	Orthosteric Ligand	alpha1_on alpha2_on
76.92	Consensus	gq_amine	Orthosteric Ligand	gq_muscarinic gq_histamine
75.00	Consensus	alpha1_on	Orthosteric Ligand	alpha1a_on
75.00	Consensus	alpha1a_on	Orthosteric Ligand	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2 7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
73.33	Single	3D4S	Timolol Maleate	3D4S-β₂-Timolol Maleate
73.33	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
73.33	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
73.33	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
73.33	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
71.43	Single	2RH1	(S)-Carazolol	2RH1-β₂-(S)-Carazolol
71.43	Single	2YCW	(S)-Carazolol	2YCW-β₁-(S)-Carazolol
71.43	Single	5D6L	(S)-Carazolol	5D6L-β₂-(S)-Carazolol
71.43	Single	5X7D	(S)-Carazolol	5X7D-β₂-(S)-Carazolol-PubChem 129318963
71.43	Consensus	5ht1_on	Orthosteric Ligand	5ht1a_on 5ht1d_on 5ht1e_on 5ht1f_on 5ht1b_on
71.43	Consensus	alpha2a_on	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
71.43	Consensus	amine_off	Orthosteric Ligand	adrenergic_off histamine_off muscarinic_off 5ht_off dopamine_off
71.43	Consensus	beta2_off	Orthosteric Ligand	6PS2-β₂-(S)-Alprenolol 6PS3-β₂-(S)-Carvedilol 6PS5-β₂-(S)-Propranolol 6PS6-β₂-Timolol 2RH1-β₂-(S)-Carazolol 6PS4-β₂-ICI 118-551 3NY9-β₂-PubChem 913103
71.43	Consensus	beta_off	Orthosteric Ligand	beta1_off beta2_off
71.43	Consensus	gs_muscarinic	Orthosteric Ligand	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
71.43	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
69.23	Single	3RZE	Cidoxepin	3RZE-H₁-Cidoxepin
69.23	Single	4LDO	L-Epinephrine	4LDO-β₂-L-Epinephrine
69.23	Single	4MQT	Iperoxo	4MQT-M₂-Iperoxo-LY2119620
69.23	Single	6K41	Dexmedetomidine	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
69.23	Single	6PS4	ICI 118-551	6PS4-β₂-ICI 118-551
69.23	Single	7CMU	Pramipexole	7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
69.23	Single	7E33	BRL-54443	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
69.23	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2
69.23	Single	7RAN	PubChem 164575847	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
69.23	Single	7UM7	Methylergometrine	7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
69.23	Single	8GEG	Epinephrine	8GEG-β₂-Epinephrine-Gs/&β;1/&γ;2
69.23	Single	8GGQ	Epinephrine	8GGQ-β₂-Epinephrine
69.23	Single	8THK	A61603	8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
69.23	Single	8UNZ	Epinephrine	8UNZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
69.23	Consensus	5ht1e_on	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
69.23	Consensus	5ht5_on	Orthosteric Ligand	5ht5a_on
69.23	Consensus	5ht5a_on	Orthosteric Ligand	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
69.23	Consensus	alpha2b_on	Orthosteric Ligand	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
69.23	Consensus	d3_on	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
69.23	Consensus	gs_tar	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2 8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
66.67	Single	2YDV	NECA	2YDV-A_2A-NECA
66.67	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
66.67	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
66.67	Single	5D5A	(S)-Carazolol	5D5A-β₂-(S)-Carazolol
66.67	Single	5D5B	(S)-Carazolol	5D5B-β₂-(S)-Carazolol
66.67	Single	5G53	NECA	5G53-A_2A-NECA-Gs
66.67	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
66.67	Single	8IRR	Rotigotine	8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2
66.67	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/&β;1/&γ;2
66.67	Single	8WC3	SEP-363856	8WC3-TA1-SEP-363856-chim(NtGi1-Gs)/&β;1/&γ;2
66.67	Consensus	beta1_off	Orthosteric Ligand	2VT4-β₁-Cyanopindolol 2YCZ-β₁-Iodocyanopindolol
66.67	Consensus	dopamine_off	Orthosteric Ligand	d3_off d2_off d4_off
66.67	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_adrenergic gi_dopamine gi_muscarinic gi_histamine
66.67	Consensus	go_adrenergic	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
66.67	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-Methyl Scopolamine 5ZHP-M₃-PubChem 134828589
66.67	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
64.29	Single	3NYA	(S)-Alprenolol	3NYA-β₂-(S)-Alprenolol
64.29	Single	3ZPQ	4-(piperazin-1- yl)-1H-indole	3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na
64.29	Single	3ZPR	4-methyl-2-(piperazin-1-yl)	3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
64.29	Single	4EJ4	Naltrindole	4EJ4-δ-Naltrindole
64.29	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
64.29	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
64.29	Single	5JQH	(S)-Carazolol	5JQH-β₂-(S)-Carazolol
64.29	Single	5YC8	N-Methyl Scopolamine	5YC8-M₂-N-Methyl Scopolamine
64.29	Single	5ZK8	N-Methyl Scopolamine	5ZK8-M₂-N-Methyl Scopolamine
64.29	Single	5ZKC	N-Methyl Scopolamine	5ZKC-M₂-N-Methyl Scopolamine
64.29	Single	6PS2	(S)-Alprenolol	6PS2-β₂-(S)-Alprenolol
64.29	Single	7BTS	L-Epinephrine	7BTS-β₁-L-Epinephrine
64.29	Single	7BU6	L-Norepinephrine	7BU6-β₁-L-Norepinephrine
64.29	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/&β;1/&γ;2
64.29	Single	7E32	Serotonin	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
64.29	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
64.29	Single	7S0G	Isoprenaline	7S0G-β₁-Isoprenaline-chim(Gi1-CtGs)/&β;1/&γ;2
64.29	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
64.29	Single	7UM5	5-CT	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2
64.29	Single	7UM6	Lisuride	7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2
64.29	Single	8GE3	Epinephrine	8GE3-β₂-Epinephrine-Gs/&β;1/&γ;2
64.29	Single	8GEE	Epinephrine	8GEE-β₂-Epinephrine-Gs/&β;1/&γ;2
64.29	Single	8GEH	Epinephrine	8GEH-β₂-Epinephrine-Gs/&β;1/&γ;2
64.29	Single	8GFW	Epinephrine	8GFW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
64.29	Single	8GFX	Epinephrine	8GFX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
64.29	Single	8GFY	Epinephrine	8GFY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
64.29	Single	8GFZ	Epinephrine	8GFZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
64.29	Single	8GG0	Epinephrine	8GG0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
64.29	Single	8GG1	Epinephrine	8GG1-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
64.29	Single	8GG2	Epinephrine	8GG2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
64.29	Single	8GG6	Epinephrine	8GG6-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
64.29	Single	8GGJ	Epinephrine	8GGJ-β₂-Epinephrine
64.29	Single	8GGN	Epinephrine	8GGN-β₂-Epinephrine
64.29	Single	8GGO	Epinephrine	8GGO-β₂-Epinephrine
64.29	Single	8GGU	Epinephrine	8GGU-β₂-Epinephrine
64.29	Single	8IRT	Rotigotine	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2
64.29	Single	8JJO	Alprenolol	8JJO-β₂-Alprenolol
64.29	Single	8JLJ	T1AM	8JLJ-TA1-T1AM-chim(NtGi1-Gs)/&β;1/&γ;2
64.29	Single	8UNN	Epinephrine	8UNN-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
64.29	Single	8UNP	Epinephrine	8UNP-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
64.29	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2
64.29	Single	8WC7	ZH8667	8WC7-TA1-ZH8667-chim(NtGi1-Gs)/&β;1/&γ;2
64.29	Single	8X63	Mepyramine	8X63-H₁-Mepyramine
64.29	Single	8X64	Desloratadine	8X64-H₁-Desloratadine
64.29	Consensus	5ht1d_on	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
64.29	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
64.29	Consensus	adrenergic_on	Orthosteric Ligand	beta_on alpha_on
64.29	Consensus	amine_on	Orthosteric Ligand	adrenergic_on histamine_on muscarinic_on tar_on 5ht_on dopamine_on
64.29	Consensus	dop_off	Orthosteric Ligand	4EJ4-δ-Naltrindole
64.29	Consensus	dopamine_on	Orthosteric Ligand	d3_on d2_on d5_on d1_on
64.29	Consensus	gi_5ht	Orthosteric Ligand	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2 8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2 7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2 7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2 7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2 7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
64.29	Consensus	go_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
64.29	Consensus	m2_on_allo	Orthosteric Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
64.29	Consensus	m4_on_allo	Orthosteric Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
64.29	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
64.29	Consensus	tar_on	Orthosteric Ligand	ta1_on
62.50	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
62.50	Single	6H7O	Cyanopindolol	6H7O-β₁-Cyanopindolol
62.50	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
62.50	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
62.50	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
62.50	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
62.50	Consensus	go_5ht	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2 7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
62.50	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_muscarinic gs_tar
62.50	Consensus	opioid_off	Orthosteric Ligand	kop_off mop_off nop_off dop_off
61.54	Single	2PED	9-cis-Retinal	2PED-Rhodopsin-9-cis-Retinal
61.54	Single	6KUY	PubChem 145704643	6KUY-α_2a-PubChem 145704643
61.54	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/&β;1/&γ;2
61.54	Single	7F24	Dopamine	7F24-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
61.54	Single	7LJD	Dopamine	7LJD-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;1
61.54	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
61.54	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
61.54	Single	7X2F	Dopamine	7X2F-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
61.54	Single	7YM8	Oxymetazoline	7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2
61.54	Single	7YMH	Norepinephrine	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2
61.54	Single	8GEC	Epinephrine	8GEC-β₂-Epinephrine-Gs/&β;1/&γ;2
61.54	Single	8GEF	Epinephrine	8GEF-β₂-Epinephrine-Gs/&β;1/&γ;2
61.54	Single	8GG9	Epinephrine	8GG9-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
61.54	Single	8GGA	Epinephrine	8GGA-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
61.54	Single	8GGV	Epinephrine	8GGV-β₂-Epinephrine
61.54	Single	8GGX	Epinephrine	8GGX-β₂-Epinephrine
61.54	Single	8GH0	Epinephrine	8GH0-β₂-Epinephrine
61.54	Single	8UNW	Epinephrine	8UNW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
61.54	Single	8UO0	Epinephrine	8UO0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
61.54	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
61.54	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
61.54	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
60.00	Single	5C1M	BU72	5C1M-μ-BU72
60.00	Single	6KUW	PubChem 57213234	6KUW-α_2c-PubChem 57213234
60.00	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
60.00	Single	6PS3	(S)-Carvedilol	6PS3-β₂-(S)-Carvedilol
60.00	Single	6PS6	Timolol	6PS6-β₂-Timolol
60.00	Single	7BVQ	(S)-Carazolol	7BVQ-β₁-(S)-Carazolol
60.00	Single	7S0F	Isoprenaline	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2
60.00	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2
60.00	Single	7WC6	LSD	7WC6-5-HT_2A-LSD
60.00	Single	7XKA	Epinephrine	7XKA-β₂-Epinephrine
60.00	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2
60.00	Single	8UNY	Epinephrine	8UNY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
60.00	Consensus	adrenergic_off	Orthosteric Ligand	beta_off alpha_off
60.00	Consensus	alpha2c_off	Orthosteric Ligand	6KUW-α_2c-PubChem 57213234
60.00	Consensus	beta2_on	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
60.00	Consensus	gi_adrenergic	Orthosteric Ligand	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2 6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
60.00	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
60.00	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
60.00	Consensus	m2_off	Orthosteric Ligand	5ZKB-M₂-AF-DX 384 5ZKC-M₂-N-Methyl Scopolamine 5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
60.00	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2 8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2 8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
58.82	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
58.82	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
58.82	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
58.82	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
58.82	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
58.82	Consensus	beta1_off_allo	Orthosteric Ligand	4BVN-β₁-Cyanopindolol-Na
58.82	Consensus	endothelin_off	Orthosteric Ligand	etb_off
58.82	Consensus	etb_off	Orthosteric Ligand	5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500 5X93-ET_B-K-8794
58.33	Single	8POK	Histamine	8POK-H₂-Histamine-Gs/&β;1/&γ;2
58.33	Single	8WC9	ZH8651	8WC9-TA1-ZH8651-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
57.14	Single	4DKL	Beta-funaltrexamine	4DKL-μ-Beta-funaltrexamine
57.14	Single	4N6H	Naltrindole	4N6H-δ-Naltrindole-Na
57.14	Single	6PS5	(S)-Propranolol	6PS5-β₂-(S)-Propranolol
57.14	Single	6TPG	EMPA	6TPG-OX₂-EMPA
57.14	Single	6TPN	HTL6641	6TPN-OX₂-HTL6641
57.14	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
57.14	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
57.14	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/&β;1/&γ;2
57.14	Single	7DHI	Salbutamol	7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
57.14	Single	7EJ8	Brimonidine	7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2
57.14	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
57.14	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
57.14	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2
57.14	Single	8FCZ	11-cis-Retinal	8FCZ-Rhodopsin-11-cis-Retinal
57.14	Single	8GE1	Epinephrine	8GE1-β₂-Epinephrine-Gs/&β;1/&γ;2
57.14	Single	8GE4	Epinephrine	8GE4-β₂-Epinephrine-Gs/&β;1/&γ;2
57.14	Single	8GE6	Epinephrine	8GE6-β₂-Epinephrine-Gs/&β;1/&γ;2
57.14	Single	8GE7	Epinephrine	8GE7-β₂-Epinephrine-Gs/&β;1/&γ;2
57.14	Single	8GE8	Epinephrine	8GE8-β₂-Epinephrine-Gs/&β;1/&γ;2
57.14	Single	8GE9	Epinephrine	8GE9-β₂-Epinephrine-Gs/&β;1/&γ;2
57.14	Single	8GFV	Epinephrine	8GFV-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
57.14	Single	8GG3	Epinephrine	8GG3-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
57.14	Single	8GG4	Epinephrine	8GG4-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
57.14	Single	8GG5	Epinephrine	8GG5-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
57.14	Single	8GGI	Epinephrine	8GGI-β₂-Epinephrine
57.14	Single	8GGK	Epinephrine	8GGK-β₂-Epinephrine
57.14	Single	8GGM	Epinephrine	8GGM-β₂-Epinephrine
57.14	Single	8GGP	Epinephrine	8GGP-β₂-Epinephrine
57.14	Single	8GGT	Epinephrine	8GGT-β₂-Epinephrine
57.14	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/&β;1/&γ;2
57.14	Single	8JLN	T1AM	8JLN-TA1-T1AM-Gs/&β;1/&γ;2
57.14	Single	8JSP	Ulotaront	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2
57.14	Single	8UNQ	Epinephrine	8UNQ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
57.14	Single	8UNR	Epinephrine	8UNR-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
57.14	Single	8UNS	Epinephrine	8UNS-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
57.14	Single	8UO2	Epinephrine	8UO2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
57.14	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2
57.14	Consensus	5ht2a_on	Orthosteric Ligand	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
57.14	Consensus	d1_on_allo	Orthosteric Ligand	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2 7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
57.14	Consensus	dop_off_allo	Orthosteric Ligand	4N6H-δ-Naltrindole-Na
57.14	Consensus	m1_off_allo	Orthosteric Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
56.25	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
56.25	Single	5V54	Methiothepin	5V54-5-HT_1B-Methiothepin
56.25	Single	5X93	K-8794	5X93-ET_B-K-8794
56.25	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
56.25	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
56.25	Single	6H7J	Isoprenaline	6H7J-β₁-Isoprenaline
56.25	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
56.25	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
56.25	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
56.25	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
56.25	Single	7JJO	Isoprenaline	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2
56.25	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2
56.25	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2
56.25	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/&β;1/&γ;2
56.25	Single	8E0G	BU72	8E0G-μ-BU72
56.25	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/&β;1/&γ;2
56.25	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/&β;1/&γ;2
56.25	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/&β;1/&γ;2
56.25	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/&β;1/&γ;2
56.25	Consensus	5ht1_off	Orthosteric Ligand	5ht1b_off
56.25	Consensus	5ht1b_off	Orthosteric Ligand	5V54-5-HT_1B-Methiothepin
56.25	Consensus	a2_on	Orthosteric Ligand	a2a_on a2b_on
56.25	Consensus	angiotensin_off	Orthosteric Ligand	at1_off at2_off
56.25	Consensus	gi_dopamine	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
56.25	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2
55.56	Single	3NY9	PubChem 913103	3NY9-β₂-PubChem 913103
55.56	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
55.56	Single	6PT3	DPI-287	6PT3-δ-DPI-287
55.56	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
55.56	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2
55.56	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
53.85	Single	1U19	11-cis-Retinal	1U19-Rhodopsin-11-cis-Retinal
53.85	Single	2G87	All-trans-retinal	2G87-Rhodopsin-All-trans-retinal
53.85	Single	2I35	11-cis-Retinal	2I35-Rhodopsin-11-cis-Retinal
53.85	Single	3PBL	Eticlopride	3PBL-D₃-Eticlopride
53.85	Single	7DFL	Histamine	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
53.85	Single	7E2Y	Serotonin	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
53.85	Single	7EJK	Oxymetazoline	7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2
53.85	Single	7SRQ	LSD	7SRQ-5-HT_2B-LSD
53.85	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2
53.85	Single	7XTB	Serotonin	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2
53.85	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/&β;1/&γ;2
53.85	Single	8GEI	Epinephrine	8GEI-β₂-Epinephrine-Gs/&β;1/&γ;2
53.85	Single	8GGS	Epinephrine	8GGS-β₂-Epinephrine
53.85	Single	8GGY	Epinephrine	8GGY-β₂-Epinephrine
53.85	Single	8ITF	DMCHA	8ITF-TAAR9-DMCHA-chim(NtGi1-Gs)/&β;1/&γ;2
53.85	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2
53.85	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2
53.85	Single	8UNV	Epinephrine	8UNV-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
53.85	Single	8UNX	Epinephrine	8UNX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
53.85	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2
53.85	Single	8W8B	SEP-363856	8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
53.85	Consensus	d3_off	Orthosteric Ligand	3PBL-D₃-Eticlopride
53.85	Consensus	gq_histamine	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
53.85	Consensus	h1_on	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
53.33	Single	1HZX	11-cis-Retinal	1HZX-Rhodopsin-11-cis-Retinal
53.33	Single	2VT4	Cyanopindolol	2VT4-β₁-Cyanopindolol
53.33	Single	2Y04	Salbutamol	2Y04-β₁-Salbutamol
53.33	Single	2YCY	Cyanopindolol	2YCY-β₁-Cyanopindolol
53.33	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
53.33	Single	4U16	N-Methyl Scopolamine	4U16-M₃-N-Methyl Scopolamine
53.33	Single	4X1H	Nonyl Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl Beta-D-Glucopyranoside-Gt(CT)
53.33	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
53.33	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
53.33	Single	6H7M	Salbutamol	6H7M-β₁-Salbutamol
53.33	Single	6PRZ	(S)-Alprenolol	6PRZ-β₂-(S)-Alprenolol
53.33	Single	6PS1	Timolol	6PS1-β₂-Timolol
53.33	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
53.33	Single	7LJC	PubChem 86764103	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2
53.33	Single	7T2G	Mitragynine pseudoindoxyl	7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2
53.33	Single	7WC7	Lisuride	7WC7-5-HT_2A-Lisuride
53.33	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
53.33	Single	7XTC	5-CT	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
53.33	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/&β;1/&γ;2
53.33	Single	8GEB	Epinephrine	8GEB-β₂-Epinephrine-Gs/&β;1/&γ;2
53.33	Single	8GGB	Epinephrine	8GGB-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
53.33	Single	8J18	(3R)-3-hydroxydodecanoic acid	8J18-GPR84-(3R)-3-hydroxydodecanoic acid-Gi1/&β;1/&γ;2
53.33	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
53.33	Single	8UNM	Epinephrine	8UNM-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
53.33	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2
53.33	Consensus	5ht1a_on	Orthosteric Ligand	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2 7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
53.33	Consensus	5ht7_on	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
53.33	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
53.33	Consensus	histamine_on	Orthosteric Ligand	h1_on h4_on
53.33	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
52.94	Single	4LDE	BI167107	4LDE-β₂-BI167107
52.94	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
52.94	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
52.94	Single	6H7N	(S)-Xamoterol	6H7N-β₁-(S)-Xamoterol
52.94	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
52.94	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
52.94	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
52.94	Single	6ZG4	HTL0009936	6ZG4-M₁-HTL0009936
52.94	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
52.94	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2
52.94	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
52.94	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
52.94	Consensus	at2_off	Orthosteric Ligand	7JNI-AT₂-Olodanrigan
52.94	Consensus	mop_on	Orthosteric Ligand	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
52.63	Single	4AMJ	(S)-Carvedilol	4AMJ-β₁-(S)-Carvedilol
52.63	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
52.63	Consensus	gi_opioid	Orthosteric Ligand	8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 7U2K-μ-C6-guano-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2 8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 7SCG-μ-FH210-Gi1/&β;1/&γ;2 7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2 7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2 7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
52.63	Consensus	mop_off	Orthosteric Ligand	7UL4-μ-Alvimopan 4DKL-μ-Beta-funaltrexamine 8QOT-μ-Nanobody E
52.38	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
50.00	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
50.00	Single	1GZM	11-cis-Retinal	1GZM-Rhodopsin-11-cis-Retinal
50.00	Single	2Y03	Isoprenaline	2Y03-β₁-Isoprenaline
50.00	Single	3C9L	11-cis-Retinal	3C9L-Rhodopsin-11-cis-Retinal
50.00	Single	5TVN	LSD	5TVN-5-HT_2B-LSD
50.00	Single	5WQC	EMPA	5WQC-OX₂-EMPA
50.00	Single	5XPR	Bosentan	5XPR-ET_B-Bosentan
50.00	Single	5ZK3	Quinuclidinyl benzilate hydrobromide	5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
50.00	Single	6AKX	A4R	6AKX-CCR5-A4R
50.00	Single	6B73	PubChem 131955138	6B73-κ-PubChem 131955138
50.00	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
50.00	Single	6E67	BI167107	6E67-β₂-BI167107-Gs (fused)
50.00	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
50.00	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
50.00	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
50.00	Single	6KUX	RS-79948	6KUX-α_2a-RS-79948
50.00	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
50.00	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
50.00	Single	6OBA	(S)-Alprenolol	6OBA-β₂-(S)-Alprenolol-GTPL11074
50.00	Single	6OY9	All-trans-retinal	6OY9-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
50.00	Single	6TOD	EMPA	6TOD-OX₁-EMPA-Na
50.00	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
50.00	Single	7DHR	Isoprenaline	7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2
50.00	Single	7EJ0	L-Norepinephrine	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2
50.00	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2
50.00	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2
50.00	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
50.00	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
50.00	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/&β;1/&γ;2
50.00	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
50.00	Single	7SRS	LSD	7SRS-5-HT_2B-LSD-Arrestin2
50.00	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2
50.00	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
50.00	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2
50.00	Single	7X5H	5-CT	7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2
50.00	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/&β;1/&γ;2
50.00	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
50.00	Single	8DPH	Lorcaserin	8DPH-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
50.00	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/&β;1/&γ;2
50.00	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
50.00	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
50.00	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2
50.00	Single	8EFO	PZM21	8EFO-μ-PZM21-Gi1/&β;1/&γ;2
50.00	Single	8GEA	Epinephrine	8GEA-β₂-Epinephrine-Gs/&β;1/&γ;2
50.00	Single	8GED	Epinephrine	8GED-β₂-Epinephrine-Gs/&β;1/&γ;2
50.00	Single	8GG7	Epinephrine	8GG7-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
50.00	Single	8GGF	Epinephrine	8GGF-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
50.00	Single	8GGW	Epinephrine	8GGW-β₂-Epinephrine
50.00	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/&β;1/&γ;2
50.00	Single	8J19	PubChem 127045422	8J19-GPR84-PubChem 127045422-Gi1/&β;1/&γ;2
50.00	Single	8UNL	Epinephrine	8UNL-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
50.00	Single	8UNO	Epinephrine	8UNO-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
50.00	Single	8UNT	Epinephrine	8UNT-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
50.00	Single	8UNU	Epinephrine	8UNU-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
50.00	Single	8UO3	Epinephrine	8UO3-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
50.00	Single	8WC5	Tetramethylammonium ion	8WC5-TA1-Tetramethylammonium ion-chim(NtGi1-Gs)/&β;1/&γ;2
50.00	Consensus	5ht2_on	Orthosteric Ligand	5ht2a_on 5ht2c_on
50.00	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide 6DRX-5-HT_2B-Lisuride
50.00	Consensus	5ht5a_off	Orthosteric Ligand	7UM4-5-HT_5A-AS2674723
50.00	Consensus	5ht_on	Orthosteric Ligand	5ht1_on 5ht2_on 5ht4_on 5ht5_on 5ht6_on 5ht7_on
50.00	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
50.00	Consensus	alpha2_off	Orthosteric Ligand	alpha2a_off alpha2c_off
50.00	Consensus	alpha2a_off	Orthosteric Ligand	6KUX-α_2a-RS-79948
50.00	Consensus	beta2_off_allo	Orthosteric Ligand	6OBA-β₂-(S)-Alprenolol-GTPL11074
50.00	Consensus	beta_on	Orthosteric Ligand	beta1_on beta2_on beta3_on
50.00	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
50.00	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
50.00	Consensus	gi_histamine	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/&β;1/&γ;2 8HOC-H₄-Imetit-Gi1/&β;1/&γ;2
50.00	Consensus	gi_nucleotide	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
50.00	Consensus	go_opioid	Orthosteric Ligand	8DZQ-κ-momSalB-Go/&β;1/&γ;2
50.00	Consensus	gq_class-a	Orthosteric Ligand	gq_amine gq_peptide
50.00	Consensus	gs_5ht	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2 7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2 7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
50.00	Consensus	gs_adrenergic	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2 7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJI-β₃-Solabegron-Gs/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
50.00	Consensus	gs_histamine	Orthosteric Ligand	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
50.00	Consensus	h4_on	Orthosteric Ligand	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
50.00	Consensus	melatonin_on	Orthosteric Ligand	mt1_on mt2_on
50.00	Consensus	opsin_off	Orthosteric Ligand	1U19-Rhodopsin-11-cis-Retinal 2PED-Rhodopsin-9-cis-Retinal 5TE5-Rhodopsin-20-Methanoretinal
47.62	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
47.62	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
47.06	Single	3P0G	BI167107	3P0G-β₂-BI167107
47.06	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/&β;1/&γ;2
47.06	Single	3UON	Quinuclidinyl benzilate hydrobromide	3UON-M₂-Quinuclidinyl benzilate hydrobromide
47.06	Single	4DJH	JDTic	4DJH-κ-JDTic
47.06	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
47.06	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
47.06	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
47.06	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/&β;1/&γ;2
47.06	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
47.06	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2
47.06	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2
47.06	Single	7EW7	PubChem 4077460	7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
47.06	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/&β;1/&γ;2
47.06	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2
47.06	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/&β;1/&γ;2
47.06	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2
47.06	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2
47.06	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
47.06	Consensus	5ht1b_on	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
47.06	Consensus	5ht5_off	Orthosteric Ligand	5ht5a_off
47.06	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
47.06	Consensus	gi_muscarinic	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
47.06	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 6GDG-A_2A-NECA-Gs/&β;1/&γ;1 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
47.06	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
47.06	Consensus	kop_off	Orthosteric Ligand	4DJH-κ-JDTic
47.06	Consensus	nk1_off	Orthosteric Ligand	6J20-NK₁-Aprepitant 6HLL-NK₁-CP99994 6E59-NK₁-L-760735
46.67	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
46.67	Single	3OAX	11-cis-Retinal	3OAX-Rhodopsin-11-cis-Retinal
46.67	Single	3UZC	PubChem 135566609	3UZC-A_2A-PubChem 135566609
46.67	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
46.67	Single	4ZJC	SB-674042	4ZJC-OX₁-SB-674042
46.67	Single	6A94	Zotepine	6A94-5-HT_2A-Zotepine
46.67	Single	6VI4	JDTic	6VI4-κ-JDTic
46.67	Single	6WH4	Methiothepin	6WH4-5-HT_2A-Methiothepin
46.67	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/&β;1/&γ;2
46.67	Single	7EJA	Dexmedetomidine	7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
46.67	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/&β;1/&γ;2
46.67	Single	7SR8	TAK-925	7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
46.67	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
46.67	Single	7ZBC	11-cis-Retinal	7ZBC-Rhodopsin-11-cis-Retinal
46.67	Single	8DPG	Psilocin	8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
46.67	Single	8GDZ	Epinephrine	8GDZ-β₂-Epinephrine-Gs/&β;1/&γ;2
46.67	Single	8GG8	Epinephrine	8GG8-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
46.67	Single	8GGL	Epinephrine	8GGL-β₂-Epinephrine
46.67	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/&β;1/&γ;2
46.67	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
46.67	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6WH4-5-HT_2A-Methiothepin 7VOE-5-HT_2A-Aripiprazole 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 6A93-5-HT_2A-Risperidone
46.67	Consensus	gi_melatonin	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2 7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
46.67	Consensus	ox1_off	Orthosteric Ligand	6TOT-OX₁-Lemborexant 6TP4-OX₁-ACT-462206 6TP6-OX₁-Filorexant 6V9S-OX₁-GTPL11403 6TP3-OX₁-Nemorexant 6TQ6-OX₁-PubChem 145714283 6TQ7-OX₁-SB-334867 6TQ9-OX₁-SB-408124 4ZJC-OX₁-SB-674042 4ZJ8-OX₁-Suvorexant
46.67	Consensus	ox2_off	Orthosteric Ligand	6TPN-OX₂-HTL6641 7XRR-OX₂-Lemborexant
46.67	Consensus	sensory_off	Orthosteric Ligand	opsin_off
46.15	Single	3PQR	All-trans-retinal	3PQR-Rhodopsin-All-trans-retinal-Gt(CT)
46.15	Single	6FUF	All-trans-retinal	6FUF-Rhodopsin-All-trans-retinal-Go/&β;1/&γ;2
46.15	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
46.15	Single	8GGR	Epinephrine	8GGR-β₂-Epinephrine
46.15	Single	8GGZ	Epinephrine	8GGZ-β₂-Epinephrine
46.15	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
46.15	Consensus	opsin_on	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
45.00	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2
45.00	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
44.44	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
44.44	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
44.44	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
44.44	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
44.44	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
44.44	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
44.44	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/&β;1/&γ;2
44.44	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
44.44	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
44.44	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
44.44	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/&β;1/&γ;2
44.44	Consensus	beta1_on	Orthosteric Ligand	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
44.44	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
44.44	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
43.75	Single	2Y01	Dobutamine	2Y01-β₁-Dobutamine
43.75	Single	2Y02	Carmoterol	2Y02-β₁-Carmoterol
43.75	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
43.75	Single	4QKX	PubChem 76210628	4QKX-β₂-PubChem 76210628
43.75	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
43.75	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
43.75	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
43.75	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
43.75	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
43.75	Single	7BU7	BI167107	7BU7-β₁-BI167107
43.75	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
43.75	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
43.75	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
43.75	Single	7SCG	FH210	7SCG-μ-FH210-Gi1/&β;1/&γ;2
43.75	Single	7SQO	TAK-925	7SQO-OX₂-TAK-925-Gi1/&β;1/&γ;2
43.75	Single	7UL4	Alvimopan	7UL4-μ-Alvimopan
43.75	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/&β;1/&γ;2
43.75	Single	7VH0	Ramelteon	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
43.75	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/&β;1/&γ;2
43.75	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
43.75	Single	7XJH	Isoproterenol	7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
43.75	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
43.75	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
43.75	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
43.75	Single	8UO4	Epinephrine	8UO4-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
43.75	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
43.75	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on
43.75	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
43.75	Consensus	blt_on	Orthosteric Ligand	blt1_on
43.75	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
43.75	Consensus	leuko_on	Orthosteric Ligand	blt_on
43.75	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on
43.75	Consensus	tachykinin_off	Orthosteric Ligand	nk1_off
42.86	Single	1L9H	11-cis-Retinal	1L9H-Rhodopsin-11-cis-Retinal
42.86	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
42.86	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
42.86	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
42.86	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
42.86	Single	7V68	Iperoxo	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
42.86	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/&β;1/&γ;2
42.86	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
42.86	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
42.86	Single	7YS6	Serotonin	7YS6-5-HT₆-Serotonin-chim(NtGi1-Gs)/&β;1/&γ;2
42.86	Single	8DPF	Lorcaserin	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
42.86	Single	8GGC	Epinephrine	8GGC-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
42.86	Single	8GGE	Epinephrine	8GGE-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
42.86	Single	8GH1	Epinephrine	8GH1-β₂-Epinephrine
42.86	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/&β;1/&γ;2
42.86	Consensus	5ht4_on	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
42.86	Consensus	gi_lpl	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2 7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
42.86	Consensus	mt2_on	Orthosteric Ligand	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
42.86	Consensus	ox1_off_allo	Orthosteric Ligand	6TOD-OX₁-EMPA-Na 6TOS-OX₁-GSK1059865-Na 6TQ4-OX₁-PubChem 16046844-Na 6TO7-OX₁-Suvorexant-Na
42.11	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
42.11	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
42.11	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/&β;1/&γ;2
42.11	Single	7EZC	UKA	7EZC-A_2A-UKA
42.11	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
42.11	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/&β;1/&γ;2
42.11	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2
42.11	Consensus	gi_class-a	Orthosteric Ligand	gi_amine gi_lipid gi_melatonin gi_peptide gi_protein gi_nucleotide gi_hcar
42.11	Consensus	s1p1_on	Orthosteric Ligand	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
41.67	Single	3PXO	All-trans-retinal	3PXO-Rhodopsin-All-trans-retinal
41.67	Single	5DYS	All-trans-retinal	5DYS-Rhodopsin-All-trans-retinal
41.18	Single	2Y00	Dobutamine	2Y00-β₁-Dobutamine
41.18	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
41.18	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
41.18	Single	5WIU	Nemonapride	5WIU-D₄-Nemonapride
41.18	Single	5WIV	Nemonapride	5WIV-D₄-Nemonapride-Na
41.18	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/&β;1/&γ;2
41.18	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
41.18	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
41.18	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
41.18	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
41.18	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
41.18	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/&β;1/&γ;2
41.18	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
41.18	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
41.18	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
41.18	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
41.18	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/&β;1/&γ;2
41.18	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
41.18	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
41.18	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
41.18	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
41.18	Consensus	a1_on_allo	Orthosteric Ligand	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
41.18	Consensus	a2a_on	Orthosteric Ligand	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
41.18	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
41.18	Consensus	d4_off	Orthosteric Ligand	5WIU-D₄-Nemonapride
41.18	Consensus	d4_off_allo	Orthosteric Ligand	5WIV-D₄-Nemonapride-Na
40.91	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
40.00	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
40.00	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
40.00	Single	5WS3	EMPA	5WS3-OX₂-EMPA
40.00	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
40.00	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
40.00	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
40.00	Single	6NWE	Octyl Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
40.00	Single	6OYA	All-trans-retinal	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
40.00	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
40.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
40.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
40.00	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
40.00	Single	7SRR	LSD	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
40.00	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/&β;1/&γ;2
40.00	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
40.00	Single	7XY6	PubChem 11717831	7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
40.00	Single	8A6C	All-trans-retinal	8A6C-Rhodopsin-All-trans-retinal
40.00	Single	8A6D	All-trans-retinal	8A6D-Rhodopsin-All-trans-retinal
40.00	Single	8A6E	All-trans-retinal	8A6E-Rhodopsin-All-trans-retinal
40.00	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2
40.00	Single	8IW4	Spermidine	8IW4-TAAR9-Spermidine-chim(NtGi1-Gs)/&β;1/&γ;2
40.00	Single	8IWE	Spermidine	8IWE-TAAR9-Spermidine
40.00	Single	8J20	Valeric acid	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
40.00	Single	8UO1	Epinephrine	8UO1-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
40.00	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
40.00	Consensus	5ht2c_on	Orthosteric Ligand	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
40.00	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
40.00	Consensus	ffa3_on_allo	Orthosteric Ligand	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
40.00	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_prostanoid gi_ffa gi_lpl gi_leukotriene
40.00	Consensus	gt_class-a	Orthosteric Ligand	gt_opsin
40.00	Consensus	gt_opsin	Orthosteric Ligand	gt_sensory
40.00	Consensus	gt_sensory	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
40.00	Consensus	orexin_off	Orthosteric Ligand	ox2_off ox1_off
38.89	Single	3PDS	Hydroxybenzylisoproterenol	3PDS-β₂-Hydroxybenzylisoproterenol
38.89	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
38.89	Single	6E59	L-760735	6E59-NK₁-L-760735
38.89	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
38.89	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/&β;1/&γ;2
38.89	Single	7EPE	NAM563	7EPE-mGlu-NAM563
38.89	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
38.89	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/&β;1/&γ;2
38.89	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2
38.89	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/&β;1/&γ;2
38.89	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2
38.89	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2
38.89	Single	8JD0	J9R	8JD0-mGlu2; mGlu3-Glutamate-J9R
38.89	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/&β;1/&γ;2
38.89	Single	8X16	Piclidenoson	8X16-A3A-Piclidenoson-Gi1/&β;1/&γ;2
38.89	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
38.89	Consensus	gs_ffa	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2 8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
38.89	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
38.89	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
38.89	Consensus	sst4_on	Orthosteric Ligand	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
38.46	Single	2HPY	All-trans-retinal	2HPY-Rhodopsin-All-trans-retinal
38.46	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
38.46	Single	8IWM	2-Phenylethylamine	8IWM-TAAR9-2-Phenylethylamine
38.46	Consensus	sensory_on	Orthosteric Ligand	opsin_on
38.10	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
37.50	Single	5TE3	Octyl Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl Beta-D-Glucopyranoside
37.50	Single	6DS0	Ly266097	6DS0-5-HT_2B-Ly266097
37.50	Single	6IQL	L745870	6IQL-D₄-L745870
37.50	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
37.50	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
37.50	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
37.50	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
37.50	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/&β;1/&γ;2
37.50	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
37.50	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/&β;1/&γ;2
37.50	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2
37.50	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
37.50	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-PubChem 25001412 5DHH-NOP-SB-612111
36.84	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
36.84	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
36.84	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
36.84	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2
36.84	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2
36.84	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
36.84	Single	7L1V	PubChem 155491009	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
36.84	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
36.84	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
36.84	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
36.84	Single	8JWY	PubChem 168451710	8JWY-A_2A-PubChem 168451710
36.84	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
36.84	Single	8T3Q	DHA	8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
36.84	Consensus	cannabinoid_off	Orthosteric Ligand	cb1_off cb2_off
36.84	Consensus	gi_class-f	Other Ligand	gi_frizzled
36.84	Consensus	gi_frizzled	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
36.84	Consensus	leuko_off	Orthosteric Ligand	blt_off cyslt_off
36.84	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z34-LPA₁-ONO-9780307 4Z35-LPA₁-ONO-9910539 7YU4-LPA₁-ONO-0740556
36.84	Consensus	peptide_off	Orthosteric Ligand	opioid_off angiotensin_off bombesin_off cck_off endothelin_off ghrelin_off npy_off nts_off orexin_off vasopressin-ot_off tachykinin_off sst_off
36.84	Consensus	s1p_on	Orthosteric Ligand	s1p3_on s1p5_on s1p1_on s1p2_on
36.36	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
36.36	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
36.00	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
35.71	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
35.71	Single	3C9M	11-cis-Retinal	3C9M-Rhodopsin-11-cis-Retinal
35.71	Single	3UZA	GTPL9236	3UZA-A_2A-GTPL9236
35.71	Single	7MT8	All-trans-retinal	7MT8-Rhodopsin-All-trans-retinal-GRK1
35.71	Single	8DPI	Lorcaserin	8DPI-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
35.71	Single	8IW7	2-Phenylethylamine	8IW7-TAAR9-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
35.71	Single	8JXT	Histamine	8JXT-H₄-Histamine-PO4-Gi1/&β;1/&γ;2
35.29	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
35.29	Single	5DHG	PubChem 25001412	5DHG-NOP-PubChem 25001412
35.29	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/&β;1/&γ;2
35.29	Single	7VIF	(S)-FTY720-P	7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2
35.29	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
35.29	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
35.29	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
35.29	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/&β;1/&γ;2
35.29	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
35.29	Single	8X17	Namodenoson	8X17-A3A-Namodenoson-Gi1/&β;1/&γ;2
35.29	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
35.00	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
35.00	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
35.00	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
35.00	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/&β;1/&γ;2
35.00	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/&β;1/&γ;2
35.00	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/&β;1/&γ;2
35.00	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
35.00	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
35.00	Consensus	class-a_on	Orthosteric Ligand	sensory_on amine_on lipid_on nucleotide_on peptide_on protein_on hcar_on steroid_on melatonin_on
35.00	Consensus	ffa4_on_allo	Orthosteric Ligand	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
35.00	Consensus	gs_orexin	Orthosteric Ligand	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
35.00	Consensus	orexin_on	Orthosteric Ligand	ox2_on
34.78	Consensus	gs_class-a	Orthosteric Ligand	gs_amine gs_nucleotide gs_lipid gs_peptide gs_protein gs_steroid
34.78	Consensus	opioid_on	Orthosteric Ligand	kop_on mop_on nop_on dop_on
33.33	Single	3AYM	All-trans-retinal	3AYM-Rhodopsin-All-trans-retinal
33.33	Single	4A4M	All-trans-retinal	4A4M-Rhodopsin-All-trans-retinal-Gt(CT)
33.33	Single	4WW3	All-trans-retinal	4WW3-Rhodopsin-All-trans-retinal
33.33	Single	5CGC	HTL14242	5CGC-mGlu₅-HTL14242
33.33	Single	5EN0	All-trans-retinal	5EN0-Rhodopsin-All-trans-retinal-Gt(CT)
33.33	Single	5NM2	ZM241385	5NM2-A_2A-ZM241385-Na
33.33	Single	5TE5	20-Methanoretinal	5TE5-Rhodopsin-20-Methanoretinal
33.33	Single	6HLL	CP99994	6HLL-NK₁-CP99994
33.33	Single	6I9K	9-cis-Retinal	6I9K-Rhodopsin-9-cis-Retinal
33.33	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
33.33	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
33.33	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
33.33	Single	6QNO	All-trans-retinal	6QNO-Rhodopsin-All-trans-retinal-Gi1/&β;1/&γ;1
33.33	Single	6TP4	ACT-462206	6TP4-OX₁-ACT-462206
33.33	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/&β;1/&γ;2
33.33	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2
33.33	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
33.33	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
33.33	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
33.33	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
33.33	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/&β;1/&γ;2
33.33	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
33.33	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/&β;1/&γ;2
33.33	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2
33.33	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/&β;1/&γ;2
33.33	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/&β;1/&γ;2
33.33	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
33.33	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on gpr119_on leuko_on lpl_on prostanoid_on
33.33	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
33.33	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
33.33	Consensus	mt1_on	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
33.33	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
32.14	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
32.14	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
32.00	Single	7KH0	Acyclovir triphosphate	7KH0-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
31.82	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2
31.82	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2
31.82	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
31.82	Single	8G59	TUG-891	8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
31.82	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/&β;1/&γ;2
31.82	Consensus	apelin_on	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
31.82	Consensus	go_class-a	Orthosteric Ligand	go_amine go_peptide go_protein
31.82	Consensus	sst_on	Orthosteric Ligand	sst2_on sst4_on
31.58	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
31.58	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
31.58	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
31.58	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2
31.58	Single	7W41	PD176252	7W41-BB₂-PD176252
31.58	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/&β;1/&γ;2
31.58	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/&β;1/&γ;2
31.58	Single	8ID6	Oleic acid	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2
31.58	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
31.58	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
31.58	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
31.58	Consensus	alpha1b_off	Orthosteric Ligand	7B6W-α_1b-Cyclazosin
31.58	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
31.58	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
31.58	Consensus	class-a_off	Orthosteric Ligand	sensory_off amine_off lipid_off nucleotide_off peptide_off protein_off hcar_off
31.58	Consensus	cyslt1_off_ortoallo	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
31.58	Consensus	ffa4_on	Orthosteric Ligand	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
31.58	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
31.25	Single	2X72	All-trans-retinal	2X72-Rhodopsin-All-trans-retinal-Gt(CT)
31.25	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
31.25	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
31.25	Single	3VGA	ZM241385	3VGA-A_2A-ZM241385-Antibody
31.25	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
31.25	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/&β;1/&γ;2
31.25	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
31.25	Single	6TQ6	PubChem 145714283	6TQ6-OX₁-PubChem 145714283
31.25	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
31.25	Single	7TUZ	7alpha,25-dihydroxycholesterol	7TUZ-GPR183-7alpha,25-dihydroxycholesterol-Gi1/&β;1/&γ;2
31.25	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/&β;1/&γ;2
31.25	Single	7XRR	Lemborexant	7XRR-OX₂-Lemborexant
31.25	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
31.25	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
31.25	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
31.25	Consensus	a2a_off_allo	Orthosteric Ligand	6ZDR-A_2A-HMS1413f12-Na 6GT3-A_2A-Imaradenant-Na 8CU7-A_2A-LJ-4517-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PubChem 92460631; psb36-Na 5MZJ-A_2A-Theophylline-Na 5OLO-A_2A-Tozadenant-Na 5OLH-A_2A-Vipadenant-Na 5NM4-A_2A-ZM241385-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5MZP-A_2A-Caffeine-Na 8CIC-A_2A-Etrumadenant-Na
31.25	Consensus	mglu_on	Other Ligand	mglu2_on mglu4_on
30.77	Single	8GEJ	Epinephrine	8GEJ-β₂-Epinephrine-Gs/&β;1/&γ;2
30.77	Consensus	gabab_off	Other Ligand	7C7S-GABA_B1, GABA_B2-CGP54626 7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid 6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
30.43	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
30.00	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
30.00	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
30.00	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
30.00	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/&β;1/&γ;2
30.00	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
30.00	Single	8I95	EP54	8I95-C3a_B-EP54-Go/&β;1/&γ;2
30.00	Single	8WU1	KCA	8WU1-CB₁-KCA-Arrestin1
30.00	Consensus	gs_bileacid	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
30.00	Consensus	gs_steroid	Orthosteric Ligand	gs_bileacid
30.00	Consensus	gs_trh	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
30.00	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
29.63	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2
29.63	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
29.41	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
29.41	Single	5JTB	ZM241385	5JTB-A_2A-ZM241385
29.41	Single	5K2B	ZM241385	5K2B-A_2A-ZM241385-Na
29.41	Single	6AQF	ZM241385	6AQF-A_2A-ZM241385
29.41	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
29.41	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
29.41	Single	6TPK	Retosiban	6TPK-OT-Retosiban
29.41	Single	6V9S	GTPL11403	6V9S-OX₁-GTPL11403
29.41	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
29.41	Single	6ZFZ	77-LH-28-1	6ZFZ-M₁-77-LH-28-1
29.41	Single	6ZG9	GSK1034702	6ZG9-M₁-GSK1034702
29.41	Single	7F61	PF-03654746	7F61-H₃-PF-03654746-Cholesterol
29.41	Single	7T32	ZM241385	7T32-A_2A-ZM241385
29.41	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
29.41	Single	7ZBE	11-cis-Retinal	7ZBE-Rhodopsin-11-cis-Retinal
29.41	Single	8GUR	PubChem 104895	8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2
29.41	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
29.41	Single	8HQN	9(S)-HODE	8HQN-GPR132-9(S)-HODE-Gi1/&β;1/&γ;2
29.41	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
29.41	Consensus	h3_on_allo	Orthosteric Ligand	7F61-H₃-PF-03654746-Cholesterol
29.41	Consensus	ot_off	Orthosteric Ligand	6TPK-OT-Retosiban
29.41	Consensus	vasopressin-ot_off	Orthosteric Ligand	ot_off
29.17	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2
29.17	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/&β;1/&γ;2
29.17	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2
29.17	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
29.17	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
29.17	Consensus	gi_formylpeptide	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2 7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
28.57	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
28.57	Single	5CGD	HTL14242	5CGD-mGlu₅-HTL14242
28.57	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
28.57	Single	6K1Q	IRL2500	6K1Q-ET_B-IRL2500
28.57	Single	7MTB	All-trans-retinal	7MTB-Rhodopsin-All-trans-retinal-GRK1
28.57	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2
28.57	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2
28.57	Single	8ID8	TUG-891	8ID8-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
28.57	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
28.57	Consensus	bileacid_on	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
28.57	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_angiotensin gq_bombesin gq_bradykinin
28.57	Consensus	gs_endothelin	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.57	Consensus	hca2_on_allo	Orthosteric Ligand	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2 8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
28.57	Consensus	steroid_on	Orthosteric Ligand	bileacid_on
28.00	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
28.00	Single	7DW9	Acyclovir triphosphate	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
28.00	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
28.00	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2
28.00	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
28.00	Consensus	gi_somatostatin	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XMT-SST4-J-2156-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
28.00	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
28.00	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
27.78	Single	3EML	ZM241385	3EML-A_2A-ZM241385
27.78	Single	4EIY	ZM241385	4EIY-A_2A-ZM241385-Na
27.78	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
27.78	Single	5K2A	ZM241385	5K2A-A_2A-ZM241385-Na
27.78	Single	5OLG	ZM241385	5OLG-A_2A-ZM241385-Na
27.78	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
27.78	Single	5UIG	J3.651.884G	5UIG-A_2A-J3.651.884G
27.78	Single	5VRA	ZM241385	5VRA-A_2A-ZM241385-Na
27.78	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
27.78	Single	6S0L	ZM241385	6S0L-A_2A-ZM241385
27.78	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
27.78	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
27.78	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
27.78	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
27.78	Single	8ID4	Linoleic acid	8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2
27.78	Consensus	a2_off	Orthosteric Ligand	a2a_off
27.78	Consensus	a2a_off	Orthosteric Ligand	8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 5UIG-A_2A-J3.651.884G 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-PubChem 168451710 5K2D-A_2A-ZM241385
27.78	Consensus	ffa_on	Orthosteric Ligand	ffa4_on ffa1_on ffa2_on ffa3_on
27.78	Consensus	gi_hca	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
27.78	Consensus	gi_hcar	Orthosteric Ligand	gi_hca
27.78	Consensus	hca2_on	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JHY-HCA₂-Compound 9n-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2 8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
27.78	Consensus	p2y12_off	Orthosteric Ligand	4NTJ-P2Y₁₂-AZD1283 7PP1-P2Y₁₂-Selatogrel
27.59	Consensus	gi_peptide	Orthosteric Ligand	gi_opioid gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_neuromedin gi_neurotensin gi_relaxin gi_neuropeptide gi_somatostatin gi_apelin gi_compl-peptide gi_cck
27.27	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
27.27	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2
27.27	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2
27.27	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
27.27	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
27.27	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
27.27	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
27.27	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
27.27	Consensus	gi_apelin	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
26.92	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/&β;1/&γ;2
26.92	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
26.92	Consensus	bombesin_on	Orthosteric Ligand	bb2_on bb1_on
26.67	Single	2ZIY	11-cis-Retinal	2ZIY-Rhodopsin-11-cis-Retinal
26.67	Single	5WKT	Octyl Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
26.67	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
26.67	Single	7MT9	All-trans-retinal	7MT9-Rhodopsin-All-trans-retinal-GRK1
26.67	Single	7MTA	All-trans-retinal	7MTA-Rhodopsin-All-trans-retinal-GRK1
26.67	Single	7WC5	Psilocin	7WC5-5-HT_2A-Psilocin
26.67	Single	8EIT	Doconexent	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
26.67	Single	8IU2	Retinal	8IU2-Opsin1LW-Retinal-Gi1/&β;1/&γ;2
26.67	Single	8J21	Butyric acid	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
26.67	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2
26.67	Single	8J6Q	Beta-hydroxybutyrate	8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
26.67	Consensus	ffa3_on	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
26.67	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
26.32	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
26.32	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
26.32	Single	5N2R	PubChem 92460631; psb36	5N2R-A_2A-PubChem 92460631; psb36-Na
26.32	Single	5N2S	PSB36	5N2S-A₁-PSB36
26.32	Single	6LPL	ZM241385	6LPL-A_2A-ZM241385-Na
26.32	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
26.32	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
26.32	Single	6S0Q	ZM241385	6S0Q-A_2A-ZM241385
26.32	Single	6WQA	ZM241385	6WQA-A_2A-ZM241385-Na
26.32	Single	7C4S	S1P	7C4S-S1P₃-S1P
26.32	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/&β;1/&γ;2
26.32	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2
26.32	Single	7RM5	ZM241385	7RM5-A_2A-ZM241385-Na
26.32	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2
26.32	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
26.32	Single	8FYN	ZM241385	8FYN-A_2A-ZM241385-Na
26.32	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
26.32	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
26.32	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/&β;1/&γ;2
26.32	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/&β;1/&γ;2
26.32	Single	8QOT	Nanobody E	8QOT-μ-Nanobody E
26.32	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
26.32	Consensus	cb2_on	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
26.09	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
26.09	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
26.09	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
26.09	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2
26.09	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
26.09	Single	8GHV	PubChem 145964903	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
26.09	Consensus	fpr-alx_on	Orthosteric Ligand	fpr1-alx_on fpr2-alx_on
26.09	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
26.09	Consensus	sst2_on	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
25.93	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
25.93	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.93	Consensus	bb1_on	Orthosteric Ligand	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.93	Consensus	gs_vasopressin-ot	Orthosteric Ligand	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
25.00	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
25.00	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
25.00	Single	5XR8	AM841	5XR8-CB₁-AM841
25.00	Single	5XRA	AM11542	5XRA-CB₁-AM11542
25.00	Single	6DO1	Angiotensin-Like peptide S1I8	6DO1-AT₁-Angiotensin-Like peptide S1I8
25.00	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
25.00	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
25.00	Single	6TQ4	PubChem 16046844	6TQ4-OX₁-PubChem 16046844-Na
25.00	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
25.00	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Single	7FEE	PubMed 104895	7FEE-CB₁-PubMed 104895-ZCZ011
25.00	Single	7P2L	4YI	7P2L-mGlu₅-4YI
25.00	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
25.00	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
25.00	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/&β;1/&γ;2
25.00	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
25.00	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/&β;1/&γ;2
25.00	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
25.00	Single	7WV9	PubMed 104895	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
25.00	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/&β;1/&γ;2
25.00	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
25.00	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
25.00	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2
25.00	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2
25.00	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/&β;1/&γ;2
25.00	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/&β;1/&γ;2
25.00	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
25.00	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
25.00	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
25.00	Single	8X2K	5YM	8X2K-GPR3-5YM-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off alpha1b_off
25.00	Consensus	arrestin2	Orthosteric Ligand	6TKO-β₁-Arformoterol-Arrestin2 6PWC-NTS₁-Neurotensin-Arrestin2 7R0C-V₂-Acyclovir triphosphate-Arrestin2
25.00	Consensus	etb_on	Orthosteric Ligand	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
25.00	Consensus	gi_ffa	Orthosteric Ligand	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2 8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
25.00	Consensus	gs_compl-peptide	Orthosteric Ligand	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Consensus	lpa1_on	Orthosteric Ligand	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
25.00	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
25.00	Consensus	npy_off	Orthosteric Ligand	npy2_off npy1_off
24.14	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
24.14	Single	8FEG	PRD_002517	8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
24.14	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2
24.14	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
24.14	Consensus	peptide_on	Orthosteric Ligand	opioid_on angiotensin_on bombesin_on cck_on endothelin_on ghrelin_on npy_on nts_on orexin_on vasopressin-ot_on tachykinin_on sst_on relaxin_on trh_on nmur_on motilin_on melanocortin_on galanin_on fpr-alx_on compl-peptide_on bradykinin_on apelin_on
24.00	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
24.00	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;2
24.00	Consensus	gi_chemerin	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
23.81	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
23.81	Single	6KQI	PubMed 104895	6KQI-CB₁-PubMed 104895-ORG27569
23.81	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
23.81	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
23.81	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
23.81	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
23.81	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2
23.81	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/&β;1/&γ;2
23.81	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2
23.81	Consensus	adgrg_on	Orthosteric Ligand	adgrg2_on adgrg3_on
23.81	Consensus	blt1_off	Orthosteric Ligand	7K15-BLT₁-MKD046-Na
23.81	Consensus	blt_off	Orthosteric Ligand	blt1_off
23.81	Consensus	cannabinoid_on	Orthosteric Ligand	cb1_on cb2_on
23.81	Consensus	cb1_off_allo	Orthosteric Ligand	6KQI-CB₁-PubMed 104895-ORG27569
23.81	Consensus	cb1_on	Orthosteric Ligand	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
23.81	Consensus	class-b2_on	Orthosteric Ligand	adgrg_on
23.81	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2 8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
23.81	Consensus	gpr119_on	Orthosteric Ligand	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2 7WCN-GPR119-AR231453-Gs/&β;1/&γ;2 7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2 7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
23.53	Single	3VG9	ZM241385	3VG9-A_2A-ZM241385-Antibody
23.53	Single	5K2D	ZM241385	5K2D-A_2A-ZM241385
23.53	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
23.53	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
23.53	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
23.53	Single	6JZH	ZM241385	6JZH-A_2A-ZM241385-Na
23.53	Single	6PS7	ZM241385	6PS7-A_2A-ZM241385-Na
23.53	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
23.53	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
23.53	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
23.53	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
23.53	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
23.53	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
23.53	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/&β;1/&γ;2
23.53	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
23.33	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
23.33	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
23.08	Single	5MZP	Caffeine	5MZP-A_2A-Caffeine-Na
23.08	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
23.08	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
23.08	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
23.08	Single	8WCB	Cyclohexylammonium ion	8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
23.08	Single	8WCC	Cyclohexylammonium ion	8WCC-TA1-Cyclohexylammonium ion
23.08	Consensus	class-d_on	Orthosteric Ligand	ste2_on
23.08	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
23.08	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
22.73	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1 (GPR40)-MK8666; PubChem 127053597
22.73	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
22.73	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
22.73	Single	8GAG	YVF	8GAG-CB₁-YVF-Gi1/&β;1/&γ;2
22.73	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
22.73	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/&β;1/&γ;2
22.73	Single	8WRZ	8D0	8WRZ-CB₁-8D0-Arrestin1
22.73	Single	8XJO	U46619	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
22.73	Consensus	cyslt2_off	Orthosteric Ligand	6RZ6-CysLT₂-ONO-2570366 6RZ9-CysLT₂-ONO-2770372 6RZ8-CysLT₂-ONO-2080365
22.73	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off
22.73	Consensus	fpa_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
22.73	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
22.73	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
22.73	Consensus	ot_on	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
22.58	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
22.22	Single	3REY	PubChem 5697	3REY-A_2A-PubChem 5697
22.22	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
22.22	Single	5IU4	ZM241385	5IU4-A_2A-ZM241385-Na
22.22	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
22.22	Single	5K2C	ZM241385	5K2C-A_2A-ZM241385-Na
22.22	Single	5NLX	ZM241385	5NLX-A_2A-ZM241385-Na
22.22	Single	5NM4	ZM241385	5NM4-A_2A-ZM241385-Na
22.22	Single	5UVI	ZM241385	5UVI-A_2A-ZM241385
22.22	Single	6FFI	MMPEP	6FFI-mGlu₅-MMPEP
22.22	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
22.22	Single	6MH8	ZM241385	6MH8-A_2A-ZM241385
22.22	Single	6ZDV	PubChem 984073	6ZDV-A_2A-PubChem 984073-Na
22.22	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
22.22	Single	7BB6	Acyclovir triphosphate	7BB6-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
22.22	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2
22.22	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
22.22	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
22.22	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
22.22	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
22.22	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
22.22	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2
22.22	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
22.22	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
22.22	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
22.22	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/&β;1/&γ;2
22.22	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/&β;1/&γ;2
22.22	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2
22.22	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
22.22	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
22.22	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
22.22	Consensus	bk1_on	Orthosteric Ligand	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
22.22	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
22.22	Consensus	ffa2_on	Orthosteric Ligand	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
22.22	Consensus	gs_bradykinin	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
22.22	Consensus	hca_on	Orthosteric Ligand	hca2_on hca3_on
22.22	Consensus	hcar_on	Orthosteric Ligand	hca_on
22.22	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
22.22	Consensus	s1p1_off	Orthosteric Ligand	3V2Y-S1P₁-PubChem 51892645
22.22	Consensus	s1p_off	Orthosteric Ligand	s1p1_off
21.88	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
21.74	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
21.74	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
21.74	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
21.74	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2
21.74	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2
21.74	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/&β;1/&γ;2
21.74	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/&β;1/&γ;2
21.74	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
21.74	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2 8I95-C3a_B-EP54-Go/&β;1/&γ;2
21.74	Consensus	go_vasopressin	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
21.43	Single	5MZJ	Theophylline	5MZJ-A_2A-Theophylline-Na
21.43	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
21.43	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
21.43	Single	7WC4	Serotonin	7WC4-5-HT_2A-Serotonin
21.43	Single	8PWN	Theophylline	8PWN-A_2A-Theophylline
21.43	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on bk1_on
21.43	Consensus	class-d_on	Orthosteric Ligand	ste2_on
21.43	Consensus	gi_neuromedin	Orthosteric Ligand	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
21.43	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
21.05	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
21.05	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
21.05	Single	5UEN	DU172	5UEN-A₁-DU172
21.05	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
21.05	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
21.05	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
21.05	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
21.05	Single	6GPS	MK0812	6GPS-CCR2-MK0812
21.05	Single	6IIV	Daltroban	6IIV-TP-Daltroban
21.05	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2
21.05	Single	6LPJ	ZM241385	6LPJ-A_2A-ZM241385-Na
21.05	Single	6LPK	ZM241385	6LPK-A_2A-ZM241385-Na
21.05	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
21.05	Single	7CFM	P395	7CFM-GPBA-P395-Gs/&β;1/&γ;2
21.05	Single	7V3Z	PubMed 104895	7V3Z-CB₁-PubMed 104895
21.05	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
21.05	Single	8EJK	TAK-875	8EJK-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
21.05	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/&β;1/&γ;2
21.05	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/&β;1/&γ;2
21.05	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
21.05	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
21.05	Consensus	cb1_on_allo	Orthosteric Ligand	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
21.05	Consensus	cck_off	Orthosteric Ligand	ccka_off
21.05	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
21.05	Consensus	ffa1_on	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
21.05	Consensus	hca3_on	Orthosteric Ligand	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
21.05	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off leuko_off lpl_off paf_off prostanoid_off
21.05	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
21.05	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491 5ZKP-PAF-Foropafant (SR27417)
21.05	Consensus	tp_off	Orthosteric Ligand	6IIV-TP-Daltroban 6IIU-TP-Ramatroban
20.83	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
20.83	Single	7QA8	Peptide	7QA8-STE2-Peptide
20.83	Single	7QA8	Peptide	7QA8-STE2-Peptide
20.83	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
20.83	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
20.83	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/&β;1/&γ;2
20.83	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin 8HN1-Alpha1A-Toxin AdTx1
20.83	Consensus	class-d_off	Orthosteric Ligand	ste2_off
20.83	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
20.69	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
20.69	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.69	Single	7F53	Alpha-MSH	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2
20.69	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
20.69	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
20.69	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
20.69	Consensus	go_class-b1	Orthosteric Ligand	go_crf
20.69	Consensus	go_crf	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
20.00	Single	3RFM	Caffeine	3RFM-A_2A-Caffeine
20.00	Single	4PHU	Fasiglifam	4PHU-FFA1 (GPR40)-Fasiglifam
20.00	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
20.00	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
20.00	Single	6GPX	MK0812	6GPX-CCR2-MK0812
20.00	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
20.00	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
20.00	Single	6TQ9	SB-408124	6TQ9-OX₁-SB-408124
20.00	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/&β;1/&γ;2
20.00	Single	7BB7	Acyclovir triphosphate	7BB7-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
20.00	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/&β;1/&γ;2
20.00	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
20.00	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/&β;1/&γ;2
20.00	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
20.00	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
20.00	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
20.00	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
20.00	Single	8F7Q	Beta-endorphin	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2
20.00	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2
20.00	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
20.00	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2
20.00	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
20.00	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
20.00	Consensus	crf1_on	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
20.00	Consensus	ep3_on	Orthosteric Ligand	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
20.00	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
20.00	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_motilin gs_neuromedin gs_orexin gs_sst gs_tachykinin gs_trh gs_vasopressin-ot gs_bombesin gs_bradykinin gs_compl-peptide gs_endothelin gs_galanin gs_ghrelin gs_melanocortin
20.00	Consensus	vasopressin-ot_on	Orthosteric Ligand	ot_on v2_on
19.35	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
19.35	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
19.23	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
19.23	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
19.23	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1
19.05	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
19.05	Single	5TZR	-	5TZR-FFA1 (GPR40)-MK8666
19.05	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/&β;1/&γ;2
19.05	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
19.05	Single	7R0C	Acyclovir triphosphate	7R0C-V₂-Acyclovir triphosphate-Arrestin2
19.05	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
19.05	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2
19.05	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
19.05	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2
19.05	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2
19.05	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
19.05	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/&β;1/&γ;2
19.05	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
19.05	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
19.05	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/&β;1/&γ;2
19.05	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
19.05	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
19.05	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
19.05	Consensus	s1p2_on	Orthosteric Ligand	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
18.75	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
18.75	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
18.75	Consensus	melanocortin_on	Orthosteric Ligand	mc2_on mc1_on mc3_on mc4_on mc5_on
18.52	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/&β;1/&γ;2
18.52	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
18.52	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/&β;1/&γ;2
18.52	Consensus	bk2_on	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
18.18	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
18.18	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
18.18	Single	6IIU	Ramatroban	6IIU-TP-Ramatroban
18.18	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
18.18	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
18.18	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2
18.18	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2
18.18	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2
18.18	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/&β;1/&γ;2
18.18	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
18.18	Consensus	dp2_off	Orthosteric Ligand	6D27-DP₂-CAY10471 6D26-DP₂-Fevipiprant
18.18	Consensus	dp_off	Orthosteric Ligand	dp2_off
18.18	Consensus	gi_prostanoid	Orthosteric Ligand	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2 8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
18.18	Consensus	prostanoid_on	Orthosteric Ligand	ep_on fpa_on
17.86	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
17.86	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.86	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/&β;1/&γ;2
17.86	Single	7X9B	Neuropeptide Y	7X9B-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
17.86	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
17.86	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
17.86	Consensus	c5a1_on	Orthosteric Ligand	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2 8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
17.65	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
17.65	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2
17.65	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/&β;1/&γ;2
17.65	Consensus	gi_neuropeptide	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2 7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2 7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
17.65	Consensus	go_adhesion	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
17.65	Consensus	go_class-b2	Orthosteric Ligand	go_adhesion
17.65	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
17.65	Consensus	npy1_on	Orthosteric Ligand	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
17.65	Consensus	npy_on	Orthosteric Ligand	npy2_on npy4_on npy1_on
17.39	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2
17.39	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2
17.39	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
17.39	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
17.39	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
17.39	Consensus	cckb_on	Orthosteric Ligand	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
17.39	Consensus	ep4_on	Orthosteric Ligand	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2
17.39	Consensus	gs_lipid	Orthosteric Ligand	gs_ffa gs_prostanoid
17.39	Consensus	gs_prostanoid	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2 7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.24	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
17.24	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
17.24	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/&β;1/&γ;2
17.24	Consensus	gi_compl-peptide	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2 7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
17.24	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
16.67	Single	3PWH	ZM241385	3PWH-A_2A-ZM241385
16.67	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
16.67	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
16.67	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
16.67	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/&β;1/&γ;2
16.67	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/&β;1/&γ;2
16.67	Single	7YOO	Neuropeptide Y	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
16.67	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2
16.67	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.67	Single	8U8F	PML	8U8F-GPR3-PML-Gs/&β;1/&γ;2
16.67	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/&β;1/&γ;2
16.67	Consensus	ccr8_on	Orthosteric Ligand	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
16.67	Consensus	class-d_off	Orthosteric Ligand	ste2_off
16.67	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
16.67	Consensus	go_compl-peptide	Orthosteric Ligand	8I95-C3a_B-EP54-Go/&β;1/&γ;2 8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2 8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2
16.67	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2 7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
16.67	Consensus	gs_adgr	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
16.67	Consensus	gs_bombesin	Orthosteric Ligand	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.67	Consensus	gs_class-b2	Orthosteric Ligand	gs_adgr
16.67	Consensus	mc4_on	Orthosteric Ligand	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
16.67	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
16.13	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2
16.13	Single	7VGX	Neuropeptide Y	7VGX-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
16.13	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
16.00	Single	5VBL	Apelin Mimetic Peptide Agonist	5VBL-Apelin-Apelin Mimetic Peptide Agonist
16.00	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
16.00	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.00	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
16.00	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/&β;1/&γ;2
16.00	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
16.00	Consensus	nmur1_on	Orthosteric Ligand	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
16.00	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
15.79	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
15.79	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
15.79	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/&β;1/&γ;2
15.79	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
15.79	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
15.79	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/&β;1/&γ;2
15.79	Single	8T3V	DHA	8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
15.79	Consensus	cb1_off	Orthosteric Ligand	5TGZ-CB₁-AM6538 5U09-CB₁-Taranabant
15.79	Consensus	gnrh_off	Orthosteric Ligand	gnrh1_off
15.62	Consensus	gs_crf	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
15.38	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
15.38	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2
15.38	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/&β;1/&γ;2
15.38	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
15.38	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
15.38	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
15.38	Consensus	cx3cr_on	Orthosteric Ligand	cx3cr1_on
15.15	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/&β;1/&γ;1
15.00	Single	6D27	CAY10471	6D27-DP₂-CAY10471
15.00	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
15.00	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
15.00	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2
15.00	Single	8EJC	TAK-875	8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
15.00	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
15.00	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/&β;1/&γ;2
15.00	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-alpha-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
15.00	Consensus	fsh_on_allo	Other Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
15.00	Consensus	hcar_off	Orthosteric Ligand	succinate_off
15.00	Consensus	prostanoid_off	Orthosteric Ligand	ep_off tp_off dp_off
15.00	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
14.81	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
14.81	Single	7F4D	Alpha-MSH	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2
14.81	Single	7O7F	(6P4)CCL5	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1
14.81	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/&β;1/&γ;2
14.81	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/&β;1/&γ;2
14.81	Consensus	cx3cr1_on	Orthosteric Ligand	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
14.81	Consensus	go_peptide	Orthosteric Ligand	go_opioid go_ghrelin go_compl-peptide go_galanin go_vasopressin
14.81	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
14.71	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
14.71	Consensus	pth1_on	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2
14.29	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
14.29	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
14.29	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
14.29	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
14.29	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
14.29	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
14.29	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
14.29	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
14.29	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
14.29	Single	7X9A	Neuropeptide Y	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
14.29	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
14.29	Single	7Y27	Somatostatin-14	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
14.29	Single	7YON	Peptide YY(3-36)	7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
14.29	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
14.29	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/&β;1/&γ;2
14.29	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
14.29	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
14.29	Consensus	ccr2_off_allo	Other Ligand	5T1A-CCR2-PubChem 68764898; PubChem 12093170 6GPX-CCR2-MK0812
14.29	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
14.29	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
14.29	Consensus	ep_off	Orthosteric Ligand	ep4_off
14.29	Consensus	go_class-b	Orthosteric Ligand	go_class-b1 go_class-b2
14.29	Consensus	gs_sst	Orthosteric Ligand	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
14.29	Consensus	nmur2_on	Orthosteric Ligand	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
14.29	Consensus	nmur_on	Orthosteric Ligand	nmur1_on nmur2_on
14.29	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
14.29	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
14.29	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
13.89	Consensus	gs_class-b	Orthosteric Ligand	gs_class-b1 gs_class-b2
13.89	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
13.79	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
13.79	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/&β;1/&γ;2
13.79	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/&β;1/&γ;2
13.79	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/&β;1/&γ;2
13.79	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2
13.79	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2
13.79	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2
13.79	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
13.79	Consensus	gs_melanocortin	Orthosteric Ligand	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2 7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2
13.79	Consensus	gs_neuromedin	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
13.79	Consensus	vpac1_on	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
13.64	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
13.64	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
13.64	Single	7XOX	Cholecystokinin-8	7XOX-CCK_B-Cholecystokinin-8-Gq/&β;1/&γ;2
13.64	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
13.64	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2
13.64	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
13.64	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
13.64	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
13.64	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
13.64	Consensus	cml1_on	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
13.64	Consensus	mglu2_on	Other Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
13.64	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
13.33	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/&β;1/&γ;2
13.33	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
13.33	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
13.33	Single	7XKE	Betahydroxyandrosterone	7XKE-ADGRG2-Betahydroxyandrosterone-chim(NtGi1-Gs)/&β;1/&γ;2
13.33	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/&β;1/&γ;2
13.33	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
13.33	Consensus	class-c_on	Other Ligand	gabab_on mglu_on
13.33	Consensus	glp1_on_allo	Orthosteric Ligand	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
13.16	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
13.16	Consensus	gs_pth	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7F16-PTH2-TIP39-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
13.04	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/&β;1/&γ;2
13.04	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2
13.04	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
13.04	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
13.04	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
13.04	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/&β;1/&γ;2
13.04	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
13.04	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2
13.04	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
13.04	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
13.04	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2
13.04	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
13.04	Consensus	ep_on	Orthosteric Ligand	ep4_on ep2_on ep3_on
13.04	Consensus	tsh_on_allo	Other Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
12.90	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
12.90	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
12.90	Consensus	gs_cgrp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
12.90	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
12.50	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
12.50	Single	6LML	Glucagon	6LML-Glucagon-Glucagon
12.50	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
12.50	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP3
12.50	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
12.50	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
12.50	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2
12.50	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2
12.50	Single	7P00	Substance P	7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
12.50	Consensus	adgrg2_on	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
12.50	Consensus	secretin_on	Orthosteric Ligand	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
12.20	Consensus	gs_class-b1	Orthosteric Ligand	gs_glucagon gs_vip-pacap gs_pth gs_calcitonin gs_crf
12.12	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/&β;1/&γ;2
12.12	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
12.00	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
12.00	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
12.00	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/&β;1/&γ;2
12.00	Single	7RMG	Substance P	7RMG-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
12.00	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
12.00	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
12.00	Single	8SAI	1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine	8SAI-GPR34-1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-Gi1/&β;1/&γ;2
12.00	Consensus	chemokine_on	Orthosteric Ligand	cxcr_on cx3cr_on
12.00	Consensus	go_ghrelin	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
12.00	Consensus	nk1_on	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
11.76	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
11.76	Single	3OE8	IT1t	3OE8-CXCR4-IT1t
11.76	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
11.76	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2
11.76	Single	7V6A	PubChem 9864275	7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
11.76	Single	8F76	-	8F76-OR51E2-Gs/&β;1/&γ;2
11.76	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/&β;1/&γ;2
11.76	Single	8FLU	Long-acting PTH	8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2
11.76	Consensus	gip_on_allo	Other Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
11.76	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
11.54	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
11.54	Single	7RMH	Substance P	7RMH-NK₁-Substance P-Gs/&β;1/&γ;2
11.54	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/&β;1/&γ;2
11.54	Consensus	protein_off	Orthosteric Ligand	ccr_off chemokine_off gnrh_off
11.43	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/&β;1/&γ;2
11.43	Consensus	vip-pacap_on	Orthosteric Ligand	vpac1_on vpac2_on pca1_on
11.11	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
11.11	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
11.11	Single	7RMI	Substance P	7RMI-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
11.11	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2
11.11	Single	7XP6	Strychnine	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
11.11	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2
11.11	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2
11.11	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/&β;1/&γ;2
11.11	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
11.11	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab-Cholesterol
11.11	Consensus	class-t_on	Orthosteric Ligand	taste2_on
11.11	Consensus	gs_class-t	Orthosteric Ligand	gs_taste
11.11	Consensus	gs_taste	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
11.11	Consensus	gs_vip-pacap	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
11.11	Consensus	taste2_on	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
10.81	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
10.71	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
10.71	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/&β;1/&γ;2
10.71	Consensus	gs_motilin	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
10.71	Consensus	gs_tachykinin	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
10.71	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
10.71	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on
10.53	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
10.53	Single	5U09	Taranabant	5U09-CB₁-Taranabant
10.53	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
10.53	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
10.53	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
10.53	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
10.53	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/&β;1/&γ;2
10.53	Single	8HMP	PubChem 69921479	8HMP-GPR52-PubChem 69921479-Gs/&β;1/&γ;2
10.53	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/&β;1/&γ;2
10.53	Consensus	p2y_off	Orthosteric Ligand	p2y1_off p2y12_off
10.34	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
10.34	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
10.34	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/&β;1/&γ;2
10.34	Consensus	ccr1_on	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
10.34	Consensus	ghrelin_on	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
10.34	Consensus	pca1_on	Orthosteric Ligand	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
10.00	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2
10.00	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
10.00	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/&β;1/&γ;2
10.00	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
10.00	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
10.00	Single	8IYX	YL-365	8IYX-GPR34-YL-365
10.00	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
10.00	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/&β;1/&γ;2
10.00	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on calcitonin_on vip-pacap_on pth_on crf_on
10.00	Consensus	glu_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2 6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2 8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2 8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2 7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2 6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
10.00	Consensus	gs_ghrelin	Orthosteric Ligand	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
9.76	Consensus	gs_calcitonin	Orthosteric Ligand	gs_ct gs_cgrp
9.68	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
9.68	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
9.68	Single	6FJ3	PTH	6FJ3-PTH1-PTH
9.68	Single	6NBF	Long-acting PTH analog	6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
9.68	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
9.68	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/&β;1/&γ;2
9.68	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
9.68	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2
9.68	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/&β;1/&γ;2
9.68	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2
9.68	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
9.68	Consensus	ghrh_on	Orthosteric Ligand	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
9.52	Single	4QIM	PubChem 24905375	4QIM-SMO-PubChem 24905375
9.52	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
9.38	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/&β;1/&γ;2; RAMP3
9.38	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/&β;1/&γ;2
9.38	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2
9.38	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
9.38	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
9.38	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
9.38	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
9.09	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
9.09	Single	6NBH	Long-acting PTH analog	6NBH-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
9.09	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
9.09	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
9.09	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/&β;1/&γ;2
9.09	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/&β;1/&γ;2
9.09	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/&β;1/&γ;2
9.09	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
9.09	Consensus	gi_chemokine	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2 7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2 7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2 7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2 8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2 6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2 8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
9.09	Consensus	glp1_on	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2 6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2 7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2 8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
9.09	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
8.82	Consensus	gip_on	Orthosteric Ligand	7DTY-GIP-GIP-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
8.70	Single	5V56	TC114	5V56-SMO-TC114
8.70	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/&β;1/&γ;2
8.70	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
8.57	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
8.33	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
8.33	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
8.33	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
8.33	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1
8.33	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2
8.33	Single	8IBU	Erythromycin A	8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8.33	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2
8.33	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2
8.33	Consensus	class-c_off	Other Ligand	gabab_off mglu_off
8.11	Consensus	gs_glucagon	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 6WZG-Secretin-Secretin-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2 7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2 7DTY-GIP-GIP-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
8.00	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/&β;1/&γ;2
8.00	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2
8.00	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
8.00	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/&β;1/&γ;2
8.00	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
8.00	Consensus	c5a1_off_ortoallo	Orthosteric Ligand	6C1Q-C5a₁-PMX53-NDT9513727 6C1R-C5a₁-PMX53-Avacopan; Na
8.00	Consensus	ep2_on	Orthosteric Ligand	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
7.89	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
7.69	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7.69	Single	8INR	Alpha-MSH	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
7.69	Consensus	motilin_on	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7.69	Consensus	protein_on	Orthosteric Ligand	ccr_on chemokine_on gphr_on chemerin_on
7.50	Consensus	glucagon_on	Orthosteric Ligand	gip_on glu_on secretin_on ghrh_on glp_on
7.41	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
7.14	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
7.14	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
7.14	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
7.14	Single	8IOC	Gamma-MSH	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
7.14	Consensus	sst_off	Orthosteric Ligand	sst2_off
6.90	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.90	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
6.90	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
6.90	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
6.90	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
6.67	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
6.67	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2
6.45	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2
6.25	Single	6NBI	Long-acting PTH analog	6NBI-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
6.25	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
6.25	Single	7V68	PubChem 57664406	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
6.25	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
6.25	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
6.25	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
6.25	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
6.06	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
6.06	Consensus	ccr_on	Orthosteric Ligand	ccr5_on ccr6_on ccr1_on ccr2_on ccr8_on
5.88	Single	7VDM	Substance P	7VDM-MRGPRX2-Substance P-Gi1/&β;1/&γ;2
5.88	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/&β;1/&γ;2
5.88	Single	7XKD	Betahydroxyandrosterone	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
5.88	Single	7Y14	Beta-alanine	7Y14-MRGPRD-Beta-alanine
5.71	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
5.71	Consensus	gip_on_allo	Orthosteric Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
5.56	Single	6LI0	GTPL9804	6LI0-GPR52-GTPL9804
5.56	Single	7S8O	(R)-Zinc-3573	7S8O-MRGPRX2-(R)-Zinc-3573-Gi1/&β;1/&γ;2
5.56	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2
5.56	Single	7Y12	Beta-alanine	7Y12-MRGPRD-Beta-alanine-Gi1/&β;1/&γ;2
5.56	Single	8JGB	Conorfamide-Tx2	8JGB-MRGPRX1-Conorfamide-Tx2-Gi1/&β;1/&γ;2
5.56	Consensus	smo_off_allo	Orthosteric Ligand	6D32-SMO-Cyclopamine-Cyclopamine
5.26	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
5.26	Single	7S8N	(R)-Zinc-3573	7S8N-MRGPRX2-(R)-Zinc-3573-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
5.26	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
5.26	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
5.26	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2
5.26	Consensus	m4_on_allo	Other Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
5.26	Consensus	smo_on_allo	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
5.00	Single	4K5Y	CP-376395	4K5Y-CRF₁-CP-376395
5.00	Single	7T94	PubChem 57664406	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
5.00	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
5.00	Single	7WV9	ZCZ011	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
5.00	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
5.00	Single	8FN0	Neurotensin/neuromedin N	8FN0-NTS₁-Neurotensin/neuromedin N-PubChem 118610427-chim(NtGi1-Go)/&β;1/&γ;2
5.00	Consensus	cb1_on_allo	Other Ligand	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
5.00	Consensus	ct_on	Orthosteric Ligand	7TYL-CT-Amylin-Gs/&β;1/&γ;2 7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
5.00	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
5.00	Consensus	m2_on_allo	Other Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
5.00	Consensus	smo_on_allo	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
4.76	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
4.76	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
4.76	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.76	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
4.76	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
4.76	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/&β;1/&γ;2
4.76	Single	8HJ5	PubChem 139030531	8HJ5-MRGPRX1-PubChem 139030531-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.76	Single	8JD6	N-(3-chlorophenyl)pyridine-2-carboxamide	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
4.76	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
4.76	Consensus	cxcr_on	Orthosteric Ligand	cxcr1_on cxcr2_on
4.76	Consensus	lh_on_allo	Other Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
4.76	Consensus	m1_off_allo	Other Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
4.55	Single	4Z9G	CP-376395	4Z9G-CRF₁-CP-376395
4.55	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
4.55	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
4.55	Single	8GTI	BMK-C205	8GTI-CRF₁-BMK-C205
4.55	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
4.55	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/&β;1/&γ;2
4.55	Consensus	smo_off	Orthosteric Ligand	5L7I-SMO-Vismodegib 4O9R-SMO-Cyclopamine 4QIM-SMO-PubChem 24905375 4JKV-SMO-Taladegib (LY2940680)
4.35	Single	4JKV	Taladegib (LY2940680)	4JKV-SMO-Taladegib (LY2940680)
4.35	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
4.35	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
4.35	Single	8FN1	Neurotensin/neuromedin N	8FN1-NTS₁-Neurotensin/neuromedin N-chim(NtGi1-Go)/&β;1/&γ;2
4.35	Single	8GTG	BMK-I152	8GTG-CRF₁-BMK-I152
4.17	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
4.17	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
4.17	Single	5V57	TC114	5V57-SMO-TC114
4.17	Single	6OS1	TRV026	6OS1-AT₁-TRV026
4.17	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
4.17	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
4.17	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
4.17	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
4.17	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
4.17	Single	8FMZ	Neurotensin/neuromedin N	8FMZ-NTS₁-Neurotensin/neuromedin N-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
4.17	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
4.17	Consensus	nts1_on_allo	Orthosteric Ligand	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
4.00	Single	4GRV	Neurotensin 8-13	4GRV-NTS₁-Neurotensin 8-13
4.00	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
4.00	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
4.00	Single	6OS2	TRV026	6OS2-AT₁-TRV026
4.00	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/&β;1/&γ;2
4.00	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/&β;1/γ1
4.00	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE
4.00	Single	8GTM	BMK-C203	8GTM-CRF₁-BMK-C203
4.00	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
4.00	Single	8JPB	Neurotensin 8-13	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
4.00	Consensus	chemokine_off	Orthosteric Ligand	cxcr_off
4.00	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II
4.00	Consensus	cxcr_off	Orthosteric Ligand	cxcr4_off
4.00	Consensus	nts1_off	Orthosteric Ligand	6Z4Q-NTS₁-SR142948A 6Z4S-NTS₁-SR48692
4.00	Consensus	nts1_on	Orthosteric Ligand	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
4.00	Consensus	nts_off	Orthosteric Ligand	nts1_off
4.00	Consensus	nts_on	Orthosteric Ligand	nts1_on
3.85	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
3.85	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
3.85	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/&β;1/&γ;2
3.85	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
3.85	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
3.85	Consensus	gi_neurotensin	Orthosteric Ligand	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1 6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
3.70	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
3.70	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/&β;1/&γ;2
3.57	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2
3.57	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
3.57	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2
3.57	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2
3.45	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/&β;1/&γ;2
3.45	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
3.45	Single	7SHF	PI; PE	7SHF-GPR158-PI; PE-B5; RGS7
3.45	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
3.33	Consensus	ccr_off	Orthosteric Ligand	ccr5_off ccr8_off
3.23	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
2.94	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2
2.86	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP1
2.86	Consensus	calcitonin_on	Orthosteric Ligand	ct_on ctlike_on
2.78	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/&β;1/&γ;2; RAMP1
2.78	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/&β;1/&γ;2
2.78	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2
2.70	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
2.63	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/&β;1/&γ;2; RAMP3
2.63	Single	8F0K	Pramlintide analogue san385	8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
2.56	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
2.56	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
2.44	Single	8F2A	Pramlintide analogue san385	8F2A-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
2.33	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/&β;1/&γ;2
2.27	Single	8F2B	Pramlintide analogue san45	8F2B-CT (AMY3)-Pramlintide analogue san45-Gs/&β;1/&γ;2; RAMP3
2.27	Consensus	gs_ct	Orthosteric Ligand	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 7TYL-CT-Amylin-Gs/&β;1/&γ;2 8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
2.17	Single	8F0J	Pramlintide analogue san45	8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2

Consensus Members
	Id	Members
	go_adrenergic	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
	go_muscarinic	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
	go_5ht	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2 7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2

Net Summary
I_min	2.36012
Number of Linked Nodes	891
Number of Links	1083
Number of Hubs	186
Number of Links mediated by Hubs	688
Number of Communities	26
Number of Nodes involved in Communities	231
Number of Links involved in Communities	332

Path Summary
Number Of Nodes in MetaPath	87
Number Of Links MetaPath	86
Number of Shortest Paths	1330494
Length Of Smallest Path	3
Average Path Length	37.7004
Length of Longest Path	66
Minimum Path Strength	0.134821
Average Path Strength	4.67525
Maximum Path Strength	21.1201
Minimum Path Correlation	0.70131
Average Path Correlation	0.973123
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.5873
Average % Of Corr. Nodes	35.2257
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	53.6534
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

This network is also present in following consensuses:
	Id	Components
	go_class-a	go_amine go_peptide go_protein

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