psnGPCR

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Click on any atom on your molecule and the corresponding residue label will be placed beneath the viewer.

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Int. Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	G.HN.36	b.b5x2	4.92	No	Yes	0	4	7
2	G.HN.37	b.b5x2	3.85	No	Yes	0	3	7
3	G.HN.40	G.HN.44	4.15	No	No	15	7	6
4	G.HN.40	b.b5x2	6.65667	No	Yes	0	7	7
5	G.HN.40	b.b5x3	6.92	No	Yes	15	7	9
6	G.HN.41	G.HN.44	4.95	No	No	0	4	6
7	G.HN.41	G.HN.45	3.83	No	No	0	4	4
8	G.HN.43	b.b5x3	4.36333	No	Yes	0	9	9
9	G.HN.44	b.b5x3	8.1	No	Yes	15	6	9
10	G.HN.46	G.HN.49	8.13667	No	No	0	4	4
11	G.HN.46	G.HN.50	5.65667	No	No	0	4	5
12	G.HN.50	b.b4x2	5.07	No	No	0	5	8
13	G.HN.51	G.hns1.02	6.18667	No	No	0	4	4
14	G.HN.51	b.l1x4	5.17	No	No	0	4	6
15	G.S1.03	G.hns1.01	19.2067	No	No	0	9	4
16	G.hns1.01	b.l1x5	3.11	No	No	0	4	7
17	G.hns1.02	I2	3.36	No	Yes	3	4	5.83333
18	G.hns1.03	I2	4.46667	No	Yes	3	5	5.83333
19	G.S1.01	G.S3.02	4.87333	No	No	0	7	4
20	G.S1.01	G.S3.04	5.47667	No	Yes	0	7	7
21	G.S1.02	G.S3.03	4.64	No	Yes	3	6	8
22	G.S1.02	G.h2s4.05	7.51333	No	No	0	6	8
23	G.S1.02	I2	7.17333	No	Yes	3	6	5.83333
24	G.S1.03	G.S3.06	4.27667	No	Yes	0	9	7
25	G.S1.05	G.h2s4.01	13.3933	No	Yes	0	9	9
26	G.S1.05	G.S4.02	3.32667	No	No	0	9	8
27	G.H1.01	G.S1.06	7.99	Yes	No	16	9	8
28	G.S1.06	G.S3.05	6.12667	No	No	0	8	8
29	G.S1.06	G.S3.07	6.33	No	No	16	8	9
30	G.H2.04	G.S1.07	3.24	No	No	0	9	8
31	G.H3.12	G.S1.07	3.80333	No	No	0	8	8
32	G.S4.07	G.s1h1.04	4.49	Yes	No	0	8	9
33	G.H3.01	G.s1h1.04	11.2467	Yes	No	0	9	9
34	G.H1.01	G.s1h1.05	4.59	Yes	No	0	9	9
35	G.S4.05	G.s1h1.05	5.92333	No	No	0	7	9
36	G.H1.01	G.S3.07	11.0633	Yes	No	16	9	9
37	G.H1.05	G.S2.04	4.76	No	No	0	7	7
38	G.H1.06	G.H1.07	3.61667	No	No	0	9	9
39	G.H1.08	G.S2.06	5.39	No	No	0	9	9
40	G.H1.09	G.S2.02	5.34333	No	No	0	8	5
41	G.H1.09	G.S2.04	4.74333	No	No	0	8	7
42	G.S2.03	G.S3.04	9.44	No	Yes	14	9	7
43	G.S2.03	G.S3.06	7.77333	No	Yes	14	9	7
44	G.S2.05	G.S3.04	14.8467	No	Yes	14	4	7
45	G.S2.06	G.S3.03	12.1433	No	Yes	0	9	8
46	G.S2.07	G.S3.02	6.6	No	No	0	3	4
47	G.S2.08	G.S3.03	4.36667	No	Yes	3	6	8
48	G.H5.05	G.S2.08	3.92333	No	No	0	5	6
49	G.H5.08	G.S2.08	8.30667	Yes	No	3	8	6
50	G.H5.05	G.s2s3.01	8.33667	No	No	0	5	5
51	G.H5.08	G.s2s3.01	9.15667	Yes	No	0	8	5
52	G.S3.01	G.S3.03	5.67667	No	Yes	3	5	8
53	G.S3.01	I2	8.50333	No	Yes	3	5	5.83333
54	G.H5.08	G.S3.03	3.93	Yes	Yes	3	8	8
55	G.S3.04	G.S3.06	12.0667	Yes	Yes	14	7	7
56	G.S3.06	b.l5x5	15.7	Yes	Yes	0	7	9
57	G.H2.07	G.S3.08	13.4833	Yes	No	0	9	9
58	G.H2.07	G.s3h2.03	5.47667	Yes	Yes	0	9	9
59	G.s3h2.03	b.l7x4	6.16	Yes	No	0	9	9
60	G.s3h2.03	b.l9x6	8.64333	Yes	Yes	2	9	8
61	G.H2.01	G.H2.03	3.87667	No	No	0	9	9
62	G.H2.03	G.H2.05	8.91667	No	Yes	0	9	8
63	G.H2.04	G.H2.07	7.33333	No	Yes	0	9	9
64	G.H2.04	G.H3.08	8.01	No	No	0	9	8
65	G.H2.05	G.H2.06	3.3	Yes	Yes	2	8	9
66	G.H2.05	b.l17x6	7.94	Yes	Yes	2	8	9
67	G.H2.06	b.l9x6	3.18667	Yes	Yes	2	9	8
68	G.H2.06	b.b14x1	8.64	Yes	No	2	9	8
69	G.H2.06	b.l15x1	4.85	Yes	No	2	9	7
70	G.H2.06	b.l17x6	6.91333	Yes	Yes	2	9	9
71	G.H2.06	b.b18x1	3.26667	Yes	No	0	9	9
72	G.H2.07	G.H2.08	5.87	Yes	No	0	9	9
73	G.H2.07	G.h2s4.01	3.67667	Yes	Yes	0	9	9
74	G.H2.08	G.H3.18	4.28333	No	No	0	9	9
75	G.H2.09	G.H3.17	12.4133	No	Yes	2	8	5
76	G.H2.09	b.l25x6	8.17667	No	Yes	2	8	8
77	G.H2.10	b.b2x1	6.27	No	Yes	2	8	8
78	G.H2.10	b.l3x1	4.57667	No	Yes	2	8	9
79	G.H2.10	b.b6x1	4.32	No	Yes	2	8	9
80	G.h2s4.01	b.l5x5	11.69	Yes	Yes	0	9	9
81	G.h2s4.02	G.h2s4.03	4.04	No	No	2	8	6
82	G.h2s4.02	b.l1x6	7.46	No	Yes	2	8	9
83	G.h2s4.02	b.l28x1	7.15667	No	Yes	2	8	9
84	G.h2s4.03	b.l1x6	4.61	No	Yes	2	6	9
85	G.S4.02	G.h3s5.03	3.92667	No	No	0	8	7
86	G.S4.03	G.S5.03	6.38	No	Yes	8	7	9
87	G.S4.03	G.S5.05	3.35	No	Yes	8	7	9
88	G.H3.08	G.S4.04	5.65333	No	No	0	8	9
89	G.H3.09	G.S4.04	4.28667	Yes	No	10	9	9
90	G.S4.04	G.S5.04	3.65	No	Yes	10	9	9
91	G.S4.05	G.S5.07	3.94	No	No	0	7	9
92	G.H3.05	G.S4.06	3.39	No	No	0	9	7
93	G.H4.15	G.S4.06	7.43	Yes	No	0	8	7
94	G.S4.07	G.s4h3.02	4.91	Yes	No	0	8	9
95	G.S4.07	G.s4h3.03	5.76667	Yes	No	0	8	8
96	G.S4.07	G.s5hg.01	11.06	Yes	Yes	0	8	9
97	G.HG.01	G.s4h3.01	3.36667	Yes	No	7	6	6
98	G.HG.04	G.s4h3.01	4	No	No	7	8	6
99	G.HG.03	G.s4h3.02	6.00667	Yes	No	0	6	9
100	G.H3.01	G.s4h3.03	6.75333	Yes	No	0	9	8
101	G.HG.07	G.s4h3.04	9.15667	No	No	0	9	4
102	G.HG.15	G.s4h3.04	11.2833	No	No	0	7	4
103	G.hgh4.01	G.s4h3.04	9.92667	No	No	0	6	4
104	G.hgh4.01	G.s4h3.15	5.81333	No	No	0	6	9
105	G.H3.01	G.H3.04	9.30667	Yes	No	0	9	9
106	G.H3.02	G.hgh4.02	4.87333	No	No	0	8	8
107	G.H3.02	G.H4.11	5.23333	No	No	0	8	8
108	G.H3.03	G.H3.06	3.10333	No	No	0	4	6
109	G.H3.03	G.H3.07	5.72	No	No	0	4	5
110	G.H3.03	G.hgh4.02	3.51333	No	No	0	4	8
111	G.H3.06	G.H4.14	3.98	No	No	0	6	5
112	G.H3.06	G.H4.15	11.3633	No	Yes	0	6	8
113	G.H3.09	G.H3.13	4.34333	Yes	Yes	10	9	6
114	G.H3.09	G.S5.02	4.36667	Yes	No	10	9	6
115	G.H3.09	G.H4.15	6.07333	Yes	Yes	10	9	8
116	G.H3.09	G.h4s6.01	4.18667	Yes	No	0	9	4
117	G.H3.10	G.H3.14	5.04333	No	No	0	5	8
118	G.H3.10	G.h4s6.01	4.29	No	No	0	5	4
119	G.H3.13	G.H3.14	5.27333	Yes	No	0	6	8
120	G.H3.13	G.S5.02	3.68	Yes	No	10	6	6
121	G.H3.13	G.h4s6.02	7.82333	Yes	No	0	6	7
122	G.H3.13	G.h4s6.13	22.9233	Yes	No	0	6	7
123	G.H3.14	G.h4s6.08	5.96	No	No	0	8	5
124	G.H3.15	G.H3.18	9.61	No	No	0	8	9
125	G.H3.16	G.H3.17	14.33	No	Yes	0	5	5
126	G.H3.16	G.h3s5.01	3.55333	No	No	0	5	3
127	G.H3.17	b.l23x1	5.21333	Yes	Yes	2	5	6
128	G.H3.17	b.l25x6	14.6633	Yes	Yes	2	5	8
129	G.H3.17	b.l28x1	3.12667	Yes	Yes	2	5	9
130	G.H5.14	G.S5.01	9.80667	No	No	0	6	8
131	G.S5.03	G.S5.05	3.35	Yes	Yes	8	9	9
132	G.H5.10	G.S5.03	6.53333	No	Yes	0	7	9
133	G.H4.15	G.S5.04	6.49667	Yes	Yes	10	8	9
134	G.S5.04	G.S6.01	3.7	Yes	No	0	9	5
135	G.S5.05	G.s6h5.01	7.78333	Yes	No	8	9	9
136	G.H5.03	G.S5.05	6.84667	Yes	Yes	8	9	9
137	G.H5.07	G.S5.05	3.76667	No	Yes	0	9	9
138	G.S5.06	G.S6.05	5.27667	No	Yes	0	8	5
139	G.S5.07	G.s5hg.01	5.13	No	Yes	0	9	9
140	G.S5.07	G.s6h5.01	4.87667	No	No	0	9	9
141	G.HG.03	G.s5hg.01	6.58	Yes	Yes	0	6	9
142	G.HG.01	G.HG.04	3.99	Yes	No	7	6	8
143	G.H4.07	G.HG.01	7.68333	No	Yes	7	5	6
144	G.HG.01	G.S6.05	10.93	Yes	Yes	7	6	5
145	G.HG.02	G.HG.03	4.52667	No	Yes	0	9	6
146	G.HG.02	G.s6h5.02	6.22333	No	No	0	9	8
147	G.HG.07	G.HG.13	5.1	No	No	0	9	7
148	G.HG.09	G.hgh4.21	4.97667	No	Yes	0	2	4
149	G.HG.14	G.HG.17	3.22667	No	No	0	6	3
150	G.HG.15	G.hgh4.05	7.95333	No	Yes	0	7	6
151	G.HG.16	G.hgh4.05	4.27667	No	Yes	0	4	6
152	G.HG.17	G.hgh4.01	4.6	No	No	0	3	6
153	G.H4.10	G.hgh4.02	5.00333	Yes	No	0	7	8
154	G.hgh4.03	G.hgh4.04	4.19333	No	No	0	6	6
155	G.H4.10	G.hgh4.04	3.5	Yes	No	0	7	6
156	G.H4.05	G.hgh4.05	16.75	No	Yes	0	5	6
157	G.H4.10	G.hgh4.05	16.4333	Yes	Yes	0	7	6
158	G.H4.10	G.hgh4.08	9.97333	Yes	No	0	7	6
159	G.H4.13	G.hgh4.08	5.37667	No	No	0	3	6
160	G.hgh4.10	G.hgh4.11	3.5	No	No	0	1	5
161	G.H4.05	G.hgh4.10	3.88	No	No	0	5	1
162	G.H4.08	G.hgh4.11	3.70667	Yes	No	0	3	5
163	G.H4.01	G.hgh4.21	5.90333	No	Yes	0	1	4
164	G.H4.02	G.hgh4.21	15.4867	No	Yes	0	5	4
165	G.H4.07	G.H4.08	4.37667	No	Yes	7	5	3
166	G.H4.07	G.S6.05	13.2367	No	Yes	7	5	5
167	G.H4.08	G.H4.12	10.6333	Yes	Yes	7	3	4
168	G.H4.08	G.S6.05	4.81333	Yes	Yes	7	3	5
169	G.H4.10	G.H4.14	9.71667	Yes	No	0	7	5
170	G.H4.12	G.H4.16	5.29667	Yes	No	7	4	4
171	G.H4.12	G.S6.03	5.76	Yes	No	7	4	5
172	G.H4.12	G.S6.05	4.98667	Yes	Yes	7	4	5
173	G.H4.13	G.H4.17	6.13333	No	No	0	3	4
174	G.H4.14	G.H4.17	6.59	No	No	0	5	4
175	G.H4.16	G.S6.03	3.87333	No	No	7	4	5
176	G.S6.01	G.h4s6.02	4.01333	No	No	0	5	7
177	G.h4s6.12	G.h4s6.13	3.38667	No	No	0	2	7
178	G.S6.02	G.h4s6.20	5.54	Yes	No	0	8	4
179	G.H5.17	G.h4s6.20	3.69	No	No	0	5	4
180	G.H5.10	G.S6.02	13.41	No	Yes	0	7	8
181	G.H5.13	G.S6.02	9.96	No	Yes	0	8	8
182	G.H5.14	G.S6.02	6.04333	No	Yes	0	6	8
183	G.H5.06	G.S6.04	11.2833	Yes	No	0	4	9
184	G.H5.10	G.S6.04	12.1867	No	No	0	7	9
185	G.H5.03	G.s6h5.01	8.28667	Yes	No	8	9	9
186	G.s6h5.02	G.s6h5.05	3.11	No	No	0	8	9
187	G.H5.03	G.s6h5.05	4.04333	Yes	No	8	9	9
188	G.H5.06	G.s6h5.05	6.75	Yes	No	8	4	9
189	G.H5.02	G.H5.06	6.20333	No	Yes	0	4	4
190	G.H5.03	G.H5.06	4.42	Yes	Yes	8	9	4
191	G.H5.05	G.H5.09	4.82333	No	No	0	5	4
192	G.H5.08	G.H5.09	3.22333	Yes	No	0	8	4
193	G.H5.08	G.H5.12	6.62667	Yes	No	3	8	7
194	G.H5.08	I2	4.98333	Yes	Yes	3	8	5.83333
195	G.H5.12	I2	10.11	No	Yes	3	7	5.83333
196	G.H5.13	G.H5.17	6.33667	No	No	0	8	5
197	G.H5.15	G.H5.19	3.68667	No	No	0	8	8
198	G.H5.15	I2	6.54667	No	Yes	3	8	5.83333
199	6x26	G.H5.17	5.39667	No	No	0	4	5
200	3x53	G.H5.19	3.61333	No	No	0	8	8
201	8x49	G.H5.21	5.68667	No	No	0	6	4
202	2x39	G.H5.23	12.0667	Yes	Yes	0	8	4
203	3x49	G.H5.23	6.89667	No	Yes	3	9	4
204	3x53	G.H5.23	7.11667	No	Yes	0	8	4
205	G.H5.23	I2	4.8	Yes	Yes	3	4	5.83333
206	2x40	G.H5.24	6.7	Yes	No	0	8	6
207	8x47	G.H5.24	9	No	No	17	8	6
208	8x50	G.H5.24	4.37333	Yes	No	17	9	6
209	3x50	G.H5.25	7.69333	No	No	0	9	8
210	6x33	G.H5.25	12.6333	No	No	0	7	8
211	b.1x11	g.h1x11	3.68667	No	Yes	0	8	9
212	b.1x13	b.1x16	4.82	No	No	0	1	4
213	b.1x18	g.l1x4	5.08333	No	Yes	0	4	8
214	b.1x19	b.b21x1	10.72	No	Yes	4	6	7
215	b.1x19	g.l1x4	4.62	No	Yes	4	6	8
216	b.lh12x2	g.l1x6	14.75	No	No	0	8	4
217	b.lh12x2	g.h2x2	8.34	No	No	0	8	9
218	b.h2x3	b.lh12x4	9.45	No	No	0	1	3
219	b.b21x4	b.h2x1	3.69	No	No	0	5	5
220	b.b21x5	b.h2x1	6.59667	Yes	No	0	4	5
221	b.h2x4	g.h2x5	3.24667	No	No	0	3	6
222	b.h2x5	b.lhb1x3	5.06667	No	Yes	0	5	2
223	b.h2x5	b.l24x2	5.40333	No	No	0	5	6
224	b.l22x5	b.lhb1x3	5.43	Yes	Yes	0	9	2
225	b.lhb1x6	b.lhb1x9	3.58333	Yes	No	0	3	3
226	b.l22x5	b.lhb1x6	5.66667	Yes	Yes	18	9	3
227	b.b24x7	b.lhb1x6	9.25	No	Yes	18	9	3
228	b.b23x1	b.lhb1x9	4.75667	No	No	0	5	3
229	b.b25x7	b.lhb1x11	4.71333	No	No	0	7	4
230	b.b1x1	b.b1x3	6.75333	No	No	0	5	7
231	b.b1x2	b.b28x4	5.50667	No	Yes	11	3	6
232	b.b1x2	b.b28x6	10.1067	No	Yes	11	3	9
233	b.b1x3	b.b28x7	8.03667	No	No	0	7	9
234	b.b1x4	b.b5x1	5.17	Yes	No	0	7	5
235	b.b1x4	b.b28x5	5.42667	Yes	No	9	7	5
236	b.b1x5	b.b28x4	7.50667	No	Yes	0	3	6
237	b.b1x6	b.b4x6	17.46	No	Yes	0	9	9
238	b.b1x6	b.b28x3	5.99667	No	No	0	9	7
239	b.b28x2	b.l1x1	7.12667	No	No	0	4	7
240	b.l1x3	b.l1x7	7.95333	Yes	No	0	9	9
241	b.b3x4	b.l1x3	5.11333	No	Yes	0	9	9
242	b.b3x6	b.l1x3	15.3433	No	Yes	0	9	9
243	b.b4x4	b.l1x3	13.7	No	Yes	0	8	9
244	b.l1x4	b.l3x2	11.31	No	No	0	6	9
245	b.b2x1	b.l1x6	7.96	Yes	Yes	2	8	9
246	b.l1x6	b.l3x1	5.42667	Yes	Yes	2	9	9
247	b.l1x6	b.l28x1	19.34	Yes	Yes	2	9	9
248	b.b2x1	b.l3x1	23.2933	Yes	Yes	2	8	9
249	b.b2x1	b.b6x1	3.19333	Yes	Yes	2	8	9
250	b.b2x3	b.b2x5	5.42667	No	Yes	0	6	7
251	b.b26x2	b.b2x3	5.4	No	No	0	7	6
252	b.b10x4	b.b2x4	10.91	Yes	No	0	6	6
253	b.b2x5	b.b3x2	11.0067	Yes	No	0	7	5
254	b.b2x5	b.l4x1	4.53	Yes	Yes	0	7	5
255	b.b2x5	b.l27x1	11.7233	Yes	No	0	7	7
256	b.b27x2	b.b2x5	4.32333	No	Yes	0	5	7
257	b.b6x5	b.l2x1	4.83	Yes	No	0	6	5
258	b.l27x2	b.l2x2	3.85667	No	No	0	1	1
259	b.l2x3	b.l2x5	3.17333	No	No	0	8	5
260	b.b3x1	b.l2x3	6.33333	No	No	0	5	8
261	b.l27x1	b.l2x4	7.46	No	No	19	7	5
262	b.l27x3	b.l2x4	7.85333	No	No	19	7	5
263	b.b4x7	b.l2x5	14.69	No	No	0	8	5
264	b.l2x5	b.l4x2	25.38	No	Yes	0	5	4
265	b.b3x1	b.b6x5	4.69	No	Yes	0	5	6
266	b.b3x2	b.b4x6	4.17667	No	Yes	0	5	9
267	b.b3x3	b.b4x3	3.47667	Yes	Yes	6	8	7
268	b.b3x3	b.b4x5	3.07333	Yes	No	6	8	7
269	b.b3x3	b.b6x3	3.41667	Yes	No	0	8	8
270	b.b3x3	b.b6x5	5.05	Yes	Yes	6	8	6
271	b.b3x3	b.b7x2	4.27667	Yes	No	6	8	8
272	b.b3x4	b.b4x6	5.76333	No	Yes	0	9	9
273	b.b28x3	b.b3x4	4	No	No	0	7	9
274	b.b3x6	b.l3x2	8.34	No	No	0	9	9
275	b.l3x1	b.l5x5	5.47667	Yes	Yes	0	9	9
276	b.b4x2	b.l3x2	6.91	No	No	0	8	9
277	b.b4x1	b.l5x1	3.42	No	Yes	0	8	8
278	b.b4x3	b.b5x7	3.33	Yes	Yes	0	7	7
279	b.b4x3	b.l5x1	6.92	Yes	Yes	6	7	8
280	b.b4x3	b.b7x4	4.23	Yes	No	6	7	8
281	b.b4x4	b.b4x6	14.0933	No	Yes	0	8	9
282	b.b4x5	b.b5x4	4.09333	No	No	6	7	5
283	b.b4x5	b.b5x5	6.18667	No	Yes	6	7	5
284	b.b4x6	b.b5x3	10.8267	Yes	Yes	0	9	9
285	b.b4x7	b.l4x3	10.5967	No	No	0	8	6
286	b.l4x1	b.l4x2	4.24	Yes	Yes	9	5	4
287	b.b28x5	b.l4x1	3.09667	No	Yes	9	5	5
288	b.b5x2	b.l4x3	10.24	Yes	No	0	7	6
289	b.b5x4	b.b5x5	6	No	Yes	6	5	5
290	b.b5x5	b.l8x8	4.61333	Yes	No	0	5	4
291	b.b5x7	b.b5x8	3.39	Yes	No	0	7	5
292	b.b5x7	b.b8x4	5.23667	Yes	Yes	0	7	6
293	b.b5x7	b.l8x8	6.14333	Yes	No	0	7	4
294	b.l5x1	b.l5x6	4.47	Yes	No	0	8	9
295	b.b7x4	b.l5x1	3.17	No	Yes	6	8	8
296	b.b8x4	b.l5x1	4.3	Yes	Yes	6	6	8
297	b.b9x3	b.l5x2	5.42667	No	No	0	6	6
298	b.l5x3	b.l7x3	9.81333	No	No	0	8	9
299	b.l5x4	b.l5x5	4.53333	No	Yes	0	8	9
300	b.l5x5	b.l7x2	5.31333	Yes	Yes	0	9	9
301	b.b6x1	b.l7x1	5.24	Yes	No	0	9	9
302	b.b6x1	b.l7x2	3.77	Yes	Yes	2	9	9
303	b.b6x1	b.l9x6	5.18667	Yes	Yes	2	9	8
304	b.b10x3	b.b6x2	3.38	Yes	No	0	8	8
305	b.b6x5	b.l6x4	4.34667	Yes	No	0	6	5
306	b.b10x5	b.l6x1	3.7	Yes	No	0	9	6
307	b.l6x3	b.l6x5	7.45	No	Yes	0	6	4
308	b.b7x1	b.l6x5	3.49	Yes	Yes	20	4	4
309	b.l6x5	b.l8x2	11.19	Yes	No	0	4	4
310	b.l10x3	b.l6x5	4.49	No	Yes	20	6	4
311	b.b7x1	b.b8x3	3.63	Yes	No	0	4	6
312	b.b7x1	b.b8x5	11.63	Yes	No	0	4	4
313	b.b7x1	b.l10x3	5.75	Yes	No	20	4	6
314	b.b7x2	b.l8x1	4.47	No	No	0	8	5
315	b.b7x4	b.b8x4	3.13667	No	Yes	6	8	6
316	b.l7x2	b.l9x6	3.12667	Yes	Yes	2	9	8
317	b.l7x3	b.l7x5	6.53333	No	No	0	9	6
318	b.l7x4	b.l9x5	5.09	No	No	0	9	8
319	b.b9x3	b.l7x5	3.64667	No	No	0	6	6
320	b.b8x1	b.b9x4	5.82	No	No	0	8	9
321	b.b8x1	b.l9x7	3.17	No	Yes	2	8	7
322	b.b10x3	b.b8x1	4.24667	Yes	No	2	8	8
323	b.b8x2	b.b8x4	4.66667	No	Yes	0	8	6
324	b.b8x2	b.b9x3	3.35333	No	No	0	8	6
325	b.b10x5	b.b8x3	3.34667	Yes	No	0	9	6
326	b.b8x3	b.l12x1	5.89	No	No	0	6	6
327	b.b8x4	b.l8x10	7.15	Yes	No	0	6	4
328	b.b8x5	b.l8x2	6.53	No	No	0	4	4
329	b.b12x6	b.b9x4	15.1867	Yes	No	0	8	9
330	b.l9x3	b.l9x7	3.85667	Yes	Yes	2	9	7
331	b.b11x4	b.l9x3	5.93667	Yes	Yes	2	9	9
332	b.b11x6	b.l9x3	9.3	Yes	Yes	2	9	9
333	b.l11x2	b.l9x3	4.2	Yes	Yes	2	9	9
334	b.b12x2	b.l9x3	3.65333	No	Yes	2	7	9
335	b.b12x6	b.l9x3	3.88	Yes	Yes	2	8	9
336	b.l11x2	b.l9x4	7.22667	Yes	No	0	9	5
337	b.b10x1	b.l9x6	3.39333	No	Yes	0	9	8
338	b.l11x1	b.l9x6	5.79333	No	Yes	2	9	8
339	b.l13x6	b.l9x6	10.3467	No	Yes	2	9	8
340	b.b14x1	b.l9x6	3.59	No	Yes	2	8	8
341	b.b11x4	b.l9x7	5.40333	Yes	Yes	2	9	7
342	b.b10x2	b.b10x4	5.57333	No	Yes	0	6	6
343	b.b10x2	b.b14x3	5.82	No	No	0	6	5
344	b.b10x3	b.b11x2	3.82	Yes	Yes	0	8	7
345	b.b10x3	b.b11x4	5.63333	Yes	Yes	2	8	9
346	b.b10x5	b.b11x2	5.86	Yes	Yes	0	9	7
347	b.b14x5	b.l10x1	3.69	No	No	0	5	3
348	b.b12x7	b.l10x4	4.04	No	No	21	9	3
349	b.l10x4	b.l12x2	4.38	No	No	21	3	6
350	b.b11x2	b.b12x6	3.52	Yes	Yes	0	7	8
351	b.b11x2	b.l12x1	3.43333	Yes	No	0	7	6
352	b.b11x3	b.b14x3	4.96667	No	No	0	5	5
353	b.b11x3	b.b15x1	6.11667	No	Yes	0	5	9
354	b.b11x4	b.b12x6	8.89667	Yes	Yes	2	9	8
355	b.b11x5	b.l13x7	4.84667	No	Yes	0	6	9
356	b.b11x6	b.l11x1	3.71	Yes	No	2	9	9
357	b.b11x6	b.l11x2	6.87333	Yes	Yes	2	9	9
358	b.l11x1	b.l13x6	5.03	No	No	2	9	9
359	b.b12x2	b.l11x2	10.6	No	Yes	2	7	9
360	b.b12x3	b.b13x7	3.72333	Yes	Yes	5	8	7
361	b.b12x3	b.l13x7	3.98333	Yes	Yes	5	8	9
362	b.b12x3	b.b15x3	3.44	Yes	No	5	8	9
363	b.b12x4	b.b12x6	3.89	No	Yes	2	4	8
364	b.b12x4	b.b13x3	5.55667	No	No	2	4	4
365	b.b12x5	b.b13x4	4.42	No	No	5	6	4
366	b.b12x5	b.b13x5	3.44	No	No	5	6	4
367	b.b12x6	b.b13x3	14.6033	Yes	No	2	8	4
368	b.b12x7	b.l12x2	4.33	No	No	21	9	6
369	b.b12x7	b.l12x3	10.12	No	No	0	9	5
370	b.b13x2	b.l12x3	4.72333	No	No	0	4	5
371	b.b13x3	b.b13x6	5.19667	No	No	0	4	4
372	b.b13x4	b.b13x5	3.14	No	No	5	4	4
373	b.b13x5	b.b13x7	6.48333	No	Yes	5	4	7
374	b.b13x7	b.b15x1	11.4333	Yes	Yes	5	7	9
375	b.b13x7	b.b16x6	15.0333	Yes	Yes	5	7	8
376	b.b13x7	b.b17x1	3.51333	Yes	No	0	7	4
377	b.l13x3	b.l13x7	5.53667	Yes	Yes	5	9	9
378	b.b15x3	b.l13x3	5.58	No	Yes	5	9	9
379	b.b15x5	b.l13x3	8.78	No	Yes	5	8	9
380	b.l13x3	b.l15x2	8.40333	Yes	Yes	5	9	9
381	b.b16x4	b.l13x3	14.8467	Yes	Yes	5	6	9
382	b.b16x6	b.l13x3	5.29333	Yes	Yes	5	8	9
383	b.l13x4	b.l15x2	6.26333	No	Yes	0	3	9
384	b.b15x5	b.l13x7	3.95667	No	Yes	5	8	9
385	b.b14x1	b.l15x1	3.24	No	No	2	8	7
386	b.b14x2	b.b18x3	5.67333	No	Yes	0	7	8
387	b.b14x4	b.b18x5	6.60667	No	Yes	0	8	5
388	b.b18x5	b.l14x1	6.00667	Yes	No	0	5	4
389	b.l14x2	b.l18x4	3.38333	No	No	0	4	7
390	b.l14x3	b.l14x5	3.17333	No	No	0	5	5
391	b.b16x7	b.l14x5	5.16	Yes	No	13	9	5
392	b.b16x5	b.l14x6	3.22667	Yes	No	0	5	3
393	b.b16x7	b.l14x6	4.52333	Yes	No	0	9	3
394	b.b15x1	b.b16x6	12.36	Yes	Yes	5	9	8
395	b.b15x2	b.b18x3	6.14333	No	Yes	4	6	8
396	b.b15x2	b.b18x5	7.43	No	Yes	0	6	5
397	b.b15x3	b.b16x6	5.35333	No	Yes	5	9	8
398	b.b15x4	b.l17x7	3.52667	No	No	0	6	7
399	b.b15x5	b.l15x2	4.11667	No	Yes	5	8	9
400	b.l15x1	b.l17x6	11.93	No	Yes	2	7	9
401	b.b16x2	b.l15x2	8.83667	No	Yes	0	5	9
402	b.b16x4	b.b16x6	6.57333	Yes	Yes	5	6	8
403	b.b16x4	b.b17x3	7.54333	Yes	No	5	6	5
404	b.b16x4	b.b17x6	12.5133	Yes	No	0	6	7
405	b.b16x5	b.b17x4	3.23667	Yes	No	0	5	5
406	b.b16x5	b.b17x5	3.54667	Yes	Yes	0	5	7
407	b.b16x5	b.l20x1	4.15333	Yes	No	0	5	6
408	b.b16x6	b.b17x3	4.78667	Yes	No	5	8	5
409	b.b16x7	b.l16x2	4.76333	Yes	No	13	9	9
410	b.b16x7	b.l16x3	17.3233	Yes	No	13	9	3
411	b.b16x7	b.b17x4	7.94333	Yes	No	13	9	5
412	b.b17x4	b.l16x3	7.75333	No	No	13	5	3
413	b.b17x3	g.h1x10	4.57667	No	No	0	5	9
414	b.b17x5	b.b17x7	9.37	Yes	Yes	4	7	8
415	b.b17x5	b.b21x1	13.9233	Yes	Yes	4	7	7
416	b.b17x5	g.l1x2	4.57333	Yes	Yes	4	7	2
417	b.b17x6	g.h1x14	4.70333	No	No	0	7	9
418	b.b17x7	b.b19x2	9.64333	Yes	Yes	4	8	6
419	b.b17x7	b.b20x6	9.29	Yes	Yes	4	8	6
420	b.b17x7	b.b21x1	5.57333	Yes	Yes	4	8	7
421	b.l17x3	b.l17x7	6.18333	Yes	No	4	9	7
422	b.b19x4	b.l17x3	7.30333	Yes	Yes	4	8	9
423	b.b19x6	b.l17x3	14.4133	No	Yes	4	9	9
424	b.l17x3	b.l19x2	5.88	Yes	Yes	4	9	9
425	b.b20x2	b.l17x3	3.65333	Yes	Yes	4	6	9
426	b.b20x4	b.l17x3	16.1733	Yes	Yes	4	8	9
427	b.l17x4	b.l19x2	9.09667	No	Yes	0	3	9
428	b.l17x5	b.l17x6	3.43667	No	Yes	2	6	9
429	b.l17x5	b.l19x1	4.41667	No	No	2	6	9
430	b.l17x6	b.l19x1	3.54667	Yes	No	2	9	9
431	b.b19x4	b.l17x7	4.56	Yes	No	4	8	7
432	b.b18x1	b.l19x1	11.22	No	No	0	9	9
433	b.b18x3	b.b19x2	5.02	Yes	Yes	4	8	6
434	b.b18x3	b.b19x4	4.05333	Yes	Yes	4	8	8
435	b.b18x4	b.b22x5	3.25667	No	Yes	0	3	7
436	b.l18x1	b.l18x2	9.14667	Yes	Yes	12	6	7
437	b.l18x1	b.l18x3	6.84667	Yes	No	0	6	5
438	b.b19x1	b.l18x1	3.23333	No	Yes	0	6	6
439	b.b22x5	b.l18x1	7.86	Yes	Yes	12	7	6
440	b.l18x1	b.l22x4	4.01667	Yes	No	12	6	9
441	b.l18x1	g.h2x8	6.09	Yes	No	0	6	7
442	b.b22x5	b.l18x2	3.37	Yes	Yes	12	7	7
443	b.l18x2	b.l22x4	4.06	Yes	No	12	7	9
444	b.l18x2	g.h2x11	5.56	Yes	No	0	7	6
445	b.l18x3	b.l18x5	10.8967	No	No	0	5	2
446	b.l18x3	g.h2x11	6.20333	No	No	0	5	6
447	b.l18x5	b.l20x2	12.8567	No	Yes	0	2	9
448	b.b19x2	b.b20x6	13.5733	Yes	Yes	4	6	6
449	b.b19x3	b.b22x5	3.23333	No	Yes	12	4	7
450	b.b19x3	b.b23x2	3.15333	No	Yes	12	4	6
451	b.b19x4	b.b20x6	4.32333	Yes	Yes	4	8	6
452	b.b19x5	b.l21x9	5.87667	No	No	0	5	6
453	b.b19x6	b.l19x2	6.38	No	Yes	4	9	9
454	b.b20x2	b.l19x2	11.08	Yes	Yes	4	6	9
455	b.b20x2	b.b20x4	5.60667	Yes	Yes	4	6	8
456	b.b20x2	b.l21x1	4.8	Yes	No	0	6	2
457	b.b20x3	b.b21x7	3.58333	No	Yes	0	8	5
458	b.b20x3	b.l21x9	4.36667	No	No	0	8	6
459	b.b20x4	b.b20x6	3.21	Yes	Yes	4	8	6
460	b.b20x4	b.b21x6	9.48667	Yes	No	4	8	1
461	b.b20x5	b.b21x4	4.61333	No	No	0	7	5
462	b.b20x5	b.b21x7	5.47	No	Yes	0	7	5
463	b.b20x6	b.b21x3	4.66333	Yes	No	4	6	6
464	b.b20x7	b.l20x2	7.14333	Yes	Yes	0	9	9
465	b.b20x7	b.l20x3	4.63	Yes	No	0	9	7
466	b.b20x7	b.b21x4	5.43	Yes	No	0	9	5
467	b.b20x7	g.h2x4	5.66333	Yes	No	0	9	7
468	b.l20x2	g.l1x5	3.75667	Yes	No	0	9	4
469	b.l20x2	g.h2x7	8.73667	Yes	No	0	9	5
470	b.b21x2	b.l20x3	3.53667	No	No	0	6	7
471	b.b21x1	g.l1x2	4.66667	Yes	Yes	4	7	2
472	b.b21x1	g.l1x4	9.13333	Yes	Yes	4	7	8
473	b.b21x2	g.h2x1	6.68667	No	No	0	6	8
474	b.b21x5	b.b21x7	9.57667	Yes	Yes	0	4	5
475	b.b21x5	b.b25x1	4.29333	Yes	No	0	4	2
476	b.b21x7	b.b23x2	5.08	Yes	Yes	0	5	6
477	b.b21x7	b.b24x6	8.04	Yes	No	0	5	8
478	b.l21x2	b.l21x4	9.77667	No	No	0	4	4
479	b.l21x2	b.l21x5	3.09333	No	No	0	4	4
480	b.b23x6	b.l21x5	5.64	Yes	No	0	7	4
481	b.b23x6	b.l21x7	3.58333	Yes	No	2	7	5
482	b.l21x7	b.l23x2	6.22	No	No	2	5	8
483	b.b23x6	b.l21x9	8.86333	Yes	No	0	7	6
484	b.b22x1	b.b22x2	3.73333	No	No	0	8	8
485	b.b22x1	b.l23x1	5.3	No	Yes	2	8	6
486	b.b22x1	b.l25x6	7.33	No	Yes	2	8	8
487	b.b22x2	b.b26x3	6.00667	No	No	0	8	6
488	b.b22x4	b.b26x5	3.77333	No	No	0	5	7
489	b.b22x5	b.b23x2	7.71333	Yes	Yes	12	7	6
490	b.b23x1	b.l22x1	6.01	No	No	0	5	9
491	b.l22x1	g.ctx3	6.37667	No	Yes	0	9	9
492	b.l22x2	g.ctx3	3.22667	No	Yes	0	1	9
493	b.l22x3	g.ctx3	9.81667	No	Yes	0	9	9
494	b.b24x7	b.l22x5	13.4967	No	Yes	18	9	9
495	b.l22x5	b.l24x2	8.90667	Yes	No	0	9	6
496	b.b23x1	b.b24x5	5.46333	No	No	0	5	5
497	b.b23x3	b.b27x1	5.96	No	No	0	7	6
498	b.b23x4	b.b23x6	4.89333	No	Yes	0	6	7
499	b.b23x5	b.b24x3	3.92	No	No	0	7	5
500	b.b23x6	b.l23x2	4.6	Yes	No	2	7	8
501	b.b23x6	b.b24x4	11.2433	Yes	Yes	0	7	6
502	b.b23x6	b.b24x6	5.79	Yes	No	0	7	8
503	b.l23x1	b.l25x6	15.0867	Yes	Yes	2	6	8
504	b.b24x2	b.l23x2	11.67	No	No	0	5	8
505	b.b24x1	b.l25x5	3.22	No	No	0	4	7
506	b.b24x2	b.b24x4	3.63333	No	Yes	0	5	6
507	b.b24x3	b.b25x7	5.82	No	No	0	5	7
508	b.b24x3	b.l25x7	5.12	No	No	0	5	7
509	b.b24x4	b.b25x3	12.8533	Yes	No	0	6	5
510	b.b24x4	b.b25x6	4.43333	Yes	No	0	6	3
511	b.b24x6	b.b25x3	6.66667	No	No	0	8	5
512	b.b24x7	b.l24x3	8.29667	No	No	0	9	5
513	b.l24x2	g.h2x12	3.70333	No	No	0	6	7
514	b.b25x7	b.b28x6	16.3233	No	Yes	0	7	9
515	b.l25x3	b.l25x7	4.15	Yes	No	0	9	7
516	b.b27x3	b.l25x3	5.93667	No	Yes	0	8	9
517	b.b27x5	b.l25x3	13.48	No	Yes	11	9	9
518	b.l25x3	b.l28x2	11.3433	Yes	No	11	9	9
519	b.b28x4	b.l25x3	10.0433	Yes	Yes	11	6	9
520	b.l25x5	b.l28x1	7.15667	No	Yes	0	7	9
521	b.l25x6	b.l28x1	18.3267	Yes	Yes	2	8	9
522	b.b26x1	b.b26x2	3.44	No	No	0	9	7
523	b.b26x1	b.l28x1	4.53	No	Yes	0	9	9
524	b.b26x3	b.b27x3	3.93	No	No	0	6	8
525	b.b26x5	b.b27x1	3.74333	No	No	0	7	6
526	b.l27x1	b.l27x3	3.85667	No	No	19	7	7
527	b.l27x3	b.l27x5	5.54333	No	No	0	7	5
528	b.l27x5	g.ctx4	6.15	No	No	0	5	7
529	b.b27x3	b.b28x6	6.87333	No	Yes	0	8	9
530	b.b27x4	b.b28x3	3.42	No	No	0	5	7
531	b.b27x5	b.l28x2	10.8	No	No	11	9	9
532	b.b28x2	b.l28x2	11.5433	No	No	0	4	9
533	b.b28x4	b.b28x6	5.41333	Yes	Yes	11	6	9
534	g.h1x5	g.h1x9	7.99	No	No	0	6	6
535	g.h1x6	g.h1x9	4.05	No	No	0	4	6
536	g.h1x10	g.h1x14	3.39667	No	No	0	9	9
537	g.l1x2	g.l1x4	8.35	Yes	Yes	4	2	8
538	g.h2x3	g.l1x5	4.36	No	No	0	5	4
539	g.h2x3	g.h2x7	4.14667	No	No	0	5	5
540	g.h2x11	g.h2x15	22.5033	No	No	0	6	6
541	g.ctx2	g.h2x15	9.84667	No	No	0	3	6
542	g.ctx3	g.ctx4	4.83	Yes	No	0	9	7
543	NT	NT	15.7733	Yes	Yes	1	4.4	4.4
544	E2	NT	11.3033	Yes	Yes	1	3.2	4.4
545	E3	NT	4.97333	Yes	Yes	1	2.71429	4.4
546	Lig	NT	14.7667	Yes	Yes	1	0	4.4
547	2x68	NT	6.6	Yes	Yes	1	4	4.4
548	7x31	NT	16.6567	No	Yes	1	4	4.4
549	2x67	NT	5.07333	No	Yes	1	5	4.4
550	1x31	NT	3.84	Yes	Yes	1	2	4.4
551	1x32	NT	6.47333	No	Yes	1	3	4.4
552	7x32	NT	3.46667	No	Yes	1	1	4.4
553	1x28	1x30	4.50333	No	No	1	2	1
554	1x28	1x31	7.89667	No	Yes	1	2	2
555	1x30	1x31	8.76333	No	Yes	1	1	2
556	1x32	2x66	4.60667	No	No	0	3	5
557	1x35	7x32	5.84333	No	No	0	4	1
558	1x35	7x35	15.5633	No	No	0	4	3
559	1x39	2x62	12.7233	No	No	0	7	6
560	1x39	7x35	5.08	No	No	0	7	3
561	1x39	7x39	7.39667	No	No	0	7	5
562	1x42	7x39	13.2033	No	No	0	7	5
563	1x45	7x47	6.53333	No	No	0	4	7
564	1x46	7x46	5.91667	No	No	0	8	9
565	1x49	7x50	3.38333	No	No	0	8	9
566	1x50	2x50	6.62667	No	Yes	0	9	9
567	1x50	7x50	6.51667	No	No	0	9	9
568	1x52	8x54	6.55333	No	No	0	6	6
569	1x54	2x47	3.23333	No	No	0	7	9
570	1x54	2x48	3.85333	No	No	0	7	6
571	1x55	1x59	6.05	No	No	0	4	4
572	1x57	2x40	6.13333	No	Yes	0	7	8
573	1x57	2x44	4.60667	No	No	0	7	6
574	1x59	1x60	3.41667	No	No	0	4	5
575	2x40	I1x50	5.14	Yes	No	0	8	7
576	2x37	2x39	3.14	No	Yes	0	7	8
577	2x38	2x41	4.20667	Yes	No	3	6	5
578	2x38	I2	11.5133	Yes	Yes	3	6	5.83333
579	2x38	4x42	3.70333	Yes	Yes	3	6	7
580	2x39	2x40	4.38333	Yes	Yes	0	8	8
581	2x40	2x43	3.27333	Yes	No	0	8	8
582	2x41	4x42	4.99	No	Yes	3	5	7
583	2x41	4x43	3.58	No	No	0	5	2
584	2x42	3x45	7.85667	Yes	No	0	7	7
585	2x42	3x49	6.76667	Yes	No	0	7	9
586	2x42	4x42	3.89	Yes	Yes	0	7	7
587	2x42	4x45	4.36667	Yes	No	0	7	5
588	2x42	4x46	5.02333	Yes	No	0	7	8
589	2x43	7x53	6.29	No	Yes	0	8	9
590	2x45	3x42	5.46333	No	No	0	9	8
591	2x45	4x46	7.55333	No	No	0	9	8
592	2x45	4x50	6.78	No	No	0	9	9
593	2x46	2x50	5.32333	Yes	Yes	22	9	9
594	2x46	3x42	4.50333	Yes	No	0	9	8
595	2x46	7x49	5.49333	Yes	No	22	9	9
596	2x48	2x52	5.28667	No	No	0	6	6
597	2x50	3x39	4.37	Yes	No	0	9	9
598	2x50	7x46	9.02	Yes	No	0	9	9
599	2x50	7x49	7.05333	Yes	No	22	9	9
600	2x52	3x31	3.15667	No	Yes	0	6	4
601	2x53	3x36	6.03333	No	No	0	7	7
602	2x53	7x42	4.33333	No	No	0	7	7
603	2x56	3x31	3.93333	No	Yes	1	5	4
604	2x57	2x61	6.81333	Yes	Yes	1	6	6
605	2x57	3x28	3.82667	Yes	Yes	1	6	5
606	2x57	3x32	5.97667	Yes	No	1	6	6
607	2x57	7x38	3.54333	Yes	Yes	1	6	5
608	2x58	7x42	5.52	No	No	0	7	7
609	2x60	E1x52	5.46667	No	Yes	1	5	7
610	2x60	3x24	6.87333	No	Yes	1	5	5
611	2x60	3x28	11.8867	No	Yes	1	5	5
612	2x61	3x28	8.12	Yes	Yes	1	6	5
613	2x61	7x34	5.04	Yes	Yes	1	6	5
614	2x61	7x38	3.27333	Yes	Yes	1	6	5
615	2x61	Lig	4.34333	Yes	Yes	1	6	0
616	2x62	2x66	5.24667	No	No	0	6	5
617	2x63	E1x52	4.16	No	Yes	0	4	7
618	2x64	2x68	3.49	Yes	Yes	1	4	4
619	2x64	E1x50	6.75333	Yes	Yes	0	4	8
620	2x64	E2	9.59333	Yes	Yes	1	4	3.2
621	2x64	Lig	8.54	Yes	Yes	1	4	0
622	2x66	2x67	4.15	No	No	0	5	5
623	2x68	E2	7.10333	Yes	Yes	1	4	3.2
624	2x68	Lig	8.86	Yes	Yes	1	4	0
625	E1x49	E1x51	8.23	No	No	0	4	2
626	E1x50	E1x52	14.67	Yes	Yes	0	8	7
627	E1x50	E2x50	9.14333	Yes	No	0	8	9
628	3x24	E1x52	5.62333	Yes	Yes	1	5	7
629	3x22	E2	5.89333	No	Yes	1	3	3.2
630	3x24	3x28	3.82333	Yes	Yes	1	5	5
631	3x25	4x65	3.44	No	No	0	9	5
632	3x25	E2	5.64667	No	Yes	1	9	3.2
633	3x25	E2x50	4.85333	No	No	1	9	9
634	3x26	4x65	4.08	No	No	0	6	5
635	3x27	3x31	8.57333	No	Yes	1	4	4
636	3x28	3x32	4.57667	Yes	No	1	5	6
637	3x29	4x65	5.96	No	No	0	5	5
638	3x29	Lig	3.66333	No	Yes	1	5	0
639	3x30	4x54	5.5	No	No	0	6	4
640	3x31	3x32	5.29667	Yes	No	1	4	6
641	3x33	3x37	5.02	Yes	Yes	0	5	7
642	3x33	4x57	3.25	Yes	No	0	5	7
643	3x33	4x61	3.66	Yes	Yes	1	5	6
644	3x33	Lig	8.41333	Yes	Yes	1	5	0
645	3x34	4x54	4.03333	No	No	0	5	4
646	3x36	3x37	4.23333	No	Yes	0	7	7
647	3x36	6x48	4.8	No	Yes	0	7	8
648	3x37	4x56	6.49667	Yes	No	0	7	5
649	3x37	5x461	12.14	Yes	No	0	7	6
650	3x38	4x50	9.29667	No	No	0	7	9
651	3x40	5x50	3.39	No	No	0	7	9
652	3x40	6x44	5.44333	No	No	1	7	9
653	3x40	6x48	5.09	No	Yes	1	7	8
654	3x44	5x53	5.29	No	No	0	7	6
655	3x46	3x50	5.57333	No	No	0	9	9
656	3x47	5x58	5.34	No	Yes	0	9	9
657	3x48	3x52	4.97667	No	No	0	5	5
658	3x49	I2	8.79333	No	Yes	3	9	5.83333
659	3x50	5x58	5.48667	No	Yes	0	9	9
660	3x51	3x55	11.8633	No	Yes	3	8	7
661	3x51	5x57	3.11	No	No	0	8	7
662	3x51	5x60	6.30667	No	No	3	8	4
663	3x52	3x56	5.25	No	No	0	5	6
664	3x54	5x61	6.63333	No	No	0	8	8
665	3x55	3x56	8.51333	Yes	No	3	7	6
666	3x55	5x60	3.63	Yes	No	3	7	4
667	3x55	5x64	4.62667	Yes	No	0	7	5
668	3x56	I2	5.14	No	Yes	3	6	5.83333
669	I2	I2	3.44333	Yes	Yes	3	5.83333	5.83333
670	4x42	I2	5.72333	Yes	Yes	3	7	5.83333
671	4x59	4x60	3.96333	No	No	0	4	8
672	4x59	4x63	6.47667	No	No	0	4	4
673	4x60	5x39	3.70667	No	Yes	0	8	6
674	4x61	E2x52	5.58667	Yes	No	1	6	4
675	4x61	5x39	9.02	Yes	Yes	1	6	6
676	4x61	Lig	5.89333	Yes	Yes	1	6	0
677	4x63	4x64	7.95333	No	No	0	4	5
678	4x64	E2	12.93	No	Yes	1	5	3.2
679	E2	E2	39.6	Yes	Yes	1	3.2	3.2
680	E2	Lig	18.3033	Yes	Yes	1	3.2	0
681	E2x50	Lig	3.74667	No	Yes	1	9	0
682	E2x51	Lig	8.45667	No	Yes	0	4	0
683	E2	E2x52	9.00667	Yes	No	1	3.2	4
684	5x36	E2	12.0433	No	Yes	1	4	3.2
685	5x39	E2	7.07333	Yes	Yes	1	6	3.2
686	5x31	E2	6.61	No	Yes	0	1	3.2
687	5x34	E2	5.53667	Yes	Yes	1	1	3.2
688	5x35	E2	7.09	No	Yes	1	4	3.2
689	5x33	5x36	5.85	No	No	0	2	4
690	5x34	5x35	3.51333	Yes	No	1	1	4
691	5x36	6x59	6.86	No	No	0	4	5
692	5x39	5x40	6.53333	Yes	No	0	6	5
693	5x39	5x43	6.73	Yes	No	0	6	5
694	5x40	6x55	4.14667	No	Yes	0	5	6
695	5x40	6x59	9.43667	No	No	0	5	5
696	5x43	5x461	3.58333	No	No	0	5	6
697	5x44	6x52	9.51	No	Yes	0	6	7
698	5x44	6x56	3.44	No	No	0	6	5
699	5x461	6x52	3.09333	No	Yes	0	6	7
700	5x47	5x48	5.84667	Yes	No	0	8	4
701	5x47	5x51	3.12667	Yes	No	0	8	6
702	5x47	6x49	12.1133	Yes	No	0	8	5
703	5x47	6x52	6.17	Yes	Yes	0	8	7
704	5x51	6x44	5.68333	No	No	0	6	9
705	5x54	5x58	4.02667	No	Yes	0	8	9
706	5x56	5x60	5.46667	No	No	0	4	4
707	5x58	6x37	11.1767	Yes	No	0	9	8
708	5x58	6x41	3.36667	Yes	No	0	9	8
709	5x61	6x37	3.55	No	No	0	8	8
710	5x62	6x34	3.68	No	No	0	5	6
711	5x65	6x30	4.70333	No	No	0	8	7
712	5x66	6x31	20.66	No	No	0	4	5
713	5x66	6x34	4.49667	No	No	0	4	6
714	6x32	7x56	4.23	No	No	0	8	7
715	6x35	6x38	3.43667	No	No	0	6	5
716	6x36	7x52	6.33667	No	No	0	8	8
717	6x43	7x48	6.65667	No	No	0	6	5
718	6x44	6x48	7.01667	No	Yes	1	9	8
719	6x47	7x40	3.17333	No	No	0	8	7
720	6x48	6x51	8.3	Yes	Yes	1	8	7
721	6x48	7x41	5.18667	Yes	No	1	8	7
722	6x48	7x45	5.76333	Yes	No	0	8	9
723	6x49	6x53	4.76	No	No	0	5	6
724	6x50	7x37	4.99667	No	No	0	9	6
725	6x51	6x52	5.92	Yes	Yes	0	7	7
726	6x51	6x55	11.2867	Yes	Yes	1	7	6
727	6x51	7x38	3.79333	Yes	Yes	1	7	5
728	6x51	7x41	5.01667	Yes	No	1	7	7
729	6x51	Lig	6.92333	Yes	Yes	1	7	0
730	6x54	6x55	7.10333	Yes	Yes	1	4	6
731	6x54	E3	10.25	Yes	Yes	1	4	2.71429
732	6x54	7x30	6.57	Yes	No	1	4	4
733	6x54	7x34	12.16	Yes	Yes	1	4	5
734	6x54	7x37	5.02667	Yes	No	0	4	6
735	6x55	Lig	10.4533	Yes	Yes	1	6	0
736	6x57	E3	5.09333	No	Yes	0	4	2.71429
737	6x58	E3	12.13	No	Yes	0	4	2.71429
738	6x61	E3	4.72333	No	Yes	1	4	2.71429
739	E3	E3	11.8733	Yes	Yes	1	2.71429	2.71429
740	7x30	E3	4.03	No	Yes	1	4	2.71429
741	E3	Lig	8.37	Yes	Yes	1	2.71429	0
742	7x29	7x33	3.93333	No	No	0	3	5
743	7x30	Lig	4.18667	No	Yes	1	4	0
744	7x31	7x32	3.84	No	No	1	4	1
745	7x31	Lig	6.63667	No	Yes	1	4	0
746	7x34	7x38	8.22667	Yes	Yes	1	5	5
747	7x34	Lig	11.6867	Yes	Yes	1	5	0
748	7x38	7x42	6.82	Yes	No	0	5	7
749	7x43	7x48	7.20667	No	No	0	5	5
750	7x47	7x48	4.39	No	No	0	7	5
751	7x49	7x53	5.81667	No	Yes	0	9	9
752	7x53	8x50	3.78333	Yes	Yes	0	9	9
753	7x54	8x54	4.19	No	No	0	7	6
754	8x47	8x49	8.43667	No	No	0	8	6
755	8x47	8x50	4.83333	No	Yes	17	8	9
756	8x48	8x51	7.14667	Yes	No	0	4	8
757	Lig	Lig	45.24	Yes	Yes	1	0	0
758	1x56	8x48	3.97667	Yes	Yes	0	8	4
759	1x58	I1x51	4.85667	No	No	0	2	6
760	I1x48	I1x50	7.03	No	No	0	6	7
761	2x37	I2	3.44	No	Yes	3	7	5.83333
762	2x39	G.H5.22	4.23333	Yes	No	0	8	4
763	2x56	3x27	3.21667	No	No	1	5	4
764	3x24	3x27	4.85667	Yes	No	1	5	4
765	3x29	4x61	3.96	No	Yes	1	5	6
766	3x30	4x62	3.17333	No	No	0	6	5
767	6x23	6x26	3.20333	No	No	0	0	4
768	7x29	E3	7.10333	No	Yes	1	3	2.71429
769	7x28	Lig	3.22667	No	Yes	0	0	0
770	b.1x2	b.1x5	4.58667	No	No	0	0	0
771	b.1x7	g.h1x8	3.27333	No	No	0	0	7
772	b.1x13	b.1x9	3.08	No	No	0	1	0
773	b.h2x2	b.lh12x4	3.2	No	No	0	1	3
774	b.lhb1x3	g.h2x9	3.88667	Yes	No	0	2	4
775	b.b1x3	g.ctx17	4.62	No	No	0	7	0
776	b.b1x4	g.ctx16	6.77	Yes	Yes	9	7	0
777	b.b1x5	b.l1x1	4.31333	No	No	0	3	7
778	b.b2x1	b.l28x1	9.32333	Yes	Yes	2	8	9
779	b.l4x1	g.ctx16	3.52	Yes	Yes	9	5	0
780	b.l4x2	g.ctx15	9.73667	Yes	No	0	4	0
781	b.l4x2	g.ctx16	3.78333	Yes	Yes	9	4	0
782	b.b10x4	b.b6x2	4.31	Yes	No	0	6	8
783	b.b6x5	b.b7x2	3.36667	Yes	No	6	6	8
784	G.s3h2.03	b.l7x2	3.55	Yes	Yes	2	9	9
785	b.b8x5	b.l8x3	3.41333	No	No	0	4	0
786	b.l8x3	b.l8x5	3.29	No	No	0	0	0
787	b.l8x5	b.l8x9	7.36333	No	No	0	0	3
788	b.l8x7	b.l8x9	3.61667	No	No	0	0	3
789	b.b11x6	b.l9x6	3.39	Yes	Yes	2	9	8
790	b.b10x3	b.l9x7	3.17333	Yes	Yes	2	8	7
791	b.b10x5	b.b14x5	3.24667	Yes	No	0	9	5
792	b.b11x1	b.l10x2	5.65667	No	No	0	5	5
793	b.b11x1	b.b12x5	3.10667	No	No	0	5	6
794	b.b12x3	b.b15x1	3.26	Yes	Yes	5	8	9
795	b.l14x5	b.l16x2	7.10667	No	No	13	5	9
796	b.b15x2	b.b19x2	8.30333	No	Yes	4	6	6
797	b.b17x2	b.l16x3	4.96	No	No	0	3	3
798	b.b20x4	b.b21x3	12.7933	Yes	No	4	8	6
799	b.b21x3	b.b21x6	3.76333	No	No	4	6	1
800	b.b25x3	b.l21x2	5.26667	No	No	0	5	4
801	b.l22x5	g.ctx6	3.23667	Yes	Yes	0	9	0
802	b.b23x3	b.b26x3	3.22667	No	No	0	7	6
803	b.b25x2	b.l24x3	4.14667	No	No	0	2	5
804	b.l27x5	g.ctx15	3.91333	No	No	0	5	0
805	b.b28x5	g.ctx16	3.34667	No	Yes	9	5	0
806	b.b28x7	g.ctx14	9.53667	No	Yes	9	9	0
807	b.b28x7	g.ctx16	3.22333	No	Yes	9	9	0
808	G.S1.04	G.S4.03	3.33	No	No	0	7	7
809	G.S1.05	G.S1.07	3.23	No	No	0	9	8
810	G.s1h1.03	G.s1h1.04	4.48667	No	No	0	8	9
811	G.H1.04	G.S4.05	4.09667	No	No	0	7	7
812	G.S2.03	G.S2.05	5.85	No	No	14	9	4
813	G.S5.06	G.s4h3.01	3.50333	No	No	0	8	6
814	G.HG.07	G.s4h3.02	4.08	No	No	0	9	9
815	G.H3.09	G.S5.04	3.65333	Yes	Yes	10	9	9
816	G.h3s5.01	G.h4s6.12	3.55333	No	No	0	3	2
817	G.HG.14	G.HG.16	4.95	No	No	0	6	4
818	G.H4.08	G.hgh4.14	5.33667	Yes	No	0	3	0
819	G.H4.08	G.hgh4.15	3.74667	Yes	No	0	3	0
820	G.hgh4.17	G.hgh4.20	7.19	No	Yes	0	0	3
821	G.H4.03	G.hgh4.20	3.80333	Yes	Yes	0	4	3
822	G.H4.04	G.hgh4.20	3.29333	No	Yes	0	4	3
823	G.h4s6.10	G.h4s6.12	8.33667	No	No	0	0	2
824	g.ctx3	g.ctx6	5.88333	Yes	Yes	0	9	0
825	g.ctx10	g.ctx13	11.0067	No	No	0	0	0
826	g.ctx14	g.ctx15	4.34667	Yes	No	0	0	0
827	g.ctx14	g.ctx16	4.83333	Yes	Yes	9	0	0
828	b.1x15	b.b21x1	4.76333	No	Yes	0	7	7
829	b.b1x4	g.ctx18	3.1	Yes	No	0	7	0
830	G.HN.30	G.HN.33	3.92667	No	No	0	0	4
831	G.H2.05	G.H3.17	3.66667	Yes	Yes	2	8	5
832	2x57	Lig	3.42333	Yes	Yes	1	6	0
833	3x28	Lig	3.85	Yes	Yes	1	5	0
834	5x32	5x34	3.77667	No	Yes	0	3	1
835	b.b21x5	b.h2x2	3.07	Yes	No	0	4	1
836	G.h2s4.01	G.h2s4.04	3.05667	Yes	No	0	9	9
837	1x48	1x49	3.05333	No	No	0	4	8
838	G.H1.05	G.S3.05	3.04333	No	No	0	7	8
839	3x44	5x54	3.04	No	No	0	7	8
840	b.h2x3	b.lh12x3	3.03333	No	No	0	1	4
841	b.b21x2	b.lh12x1	3.03333	No	No	0	6	3
842	1x38	7x39	3.02333	No	No	0	4	5
843	G.H2.01	b.b12x1	3.01667	No	No	0	9	6
844	G.HG.16	G.hgh4.06	3.01667	No	No	0	4	2
845	b.b2x2	b.b6x3	3.01	No	No	0	7	8
846	b.l22x1	g.ctx5	3.00333	No	No	0	9	9
847	b.b13x1	b.b9x2	3	No	No	0	4	5
848	G.HN.32	G.HN.33	2.99	No	No	0	6	4
849	b.b22x3	b.b23x2	2.98	No	Yes	0	6	6
850	5x65	6x34	2.98	No	No	0	8	6
851	b.b7x1	b.b9x1	2.96667	Yes	No	0	4	4
852	2x43	3x46	2.96667	No	No	0	8	9
853	2x63	E1x51	2.93333	No	No	0	4	2
854	1x56	8x50	2.93	Yes	Yes	0	8	9
855	b.b9x2	b.l12x1	2.92667	No	No	0	5	6
856	G.H4.03	G.hgh4.21	2.92	Yes	Yes	0	4	4
857	b.lh12x2	g.h2x1	2.92	No	No	0	8	8
858	b.b26x4	b.b2x3	2.91	No	No	0	5	6
859	G.H1.01	G.s1h1.01	2.90333	Yes	No	0	9	9
860	G.HN.34	G.HN.37	2.88667	No	No	0	4	3
861	G.HN.43	G.HN.47	2.85	No	No	0	9	5
862	6x60	6x61	2.83333	No	No	0	5	4
863	G.H4.03	G.HG.05	2.82667	Yes	No	0	4	4
864	b.b18x2	b.b22x3	2.82667	No	No	0	5	6
865	6x36	7x56	2.82667	No	No	0	8	7
866	3x41	4x49	2.82333	No	No	0	5	7
867	b.b17x6	g.h1x11	2.82333	No	Yes	0	7	9
868	b.1x12	b.1x13	2.79667	No	No	0	6	1
869	b.l21x8	b.l23x1	2.79333	No	Yes	0	4	6
870	G.H5.11	G.S3.03	2.79	No	Yes	0	8	8
871	3x30	4x59	2.78667	No	No	0	6	4
872	5x37	6x59	2.78667	No	No	0	3	5
873	G.H5.04	G.S2.06	2.77	No	No	0	8	9
874	I1x48	b.l25x4	2.76667	No	No	0	6	5
875	g.h1x2	g.h1x6	2.71333	No	No	0	0	4
876	G.HN.43	b.b5x6	2.70667	No	No	0	9	6
877	G.S4.01	G.S5.03	2.70667	No	Yes	0	8	9
878	g.h2x13	g.h2x9	2.70667	No	No	0	1	4
879	b.l27x4	g.ctx4	2.70667	No	No	0	9	7
880	b.lhb1x4	b.lhb1x5	2.68333	No	No	0	1	1
881	2x65	7x34	2.67	No	Yes	0	5	5
882	b.1x11	b.1x7	2.65	No	No	0	8	0
883	G.HN.39	b.b5x5	2.63333	No	Yes	0	4	5
884	5x51	6x45	2.62667	No	No	0	6	5
885	g.h1x11	g.h1x7	2.62333	Yes	No	0	9	2
886	1x53	8x50	2.62	No	Yes	0	8	9
887	b.l21x7	b.l23x1	2.59667	No	Yes	2	5	6
888	1x46	7x47	2.55333	No	No	0	8	7
889	1x54	2x44	2.55	No	No	0	7	6
890	1x50	2x51	2.54	No	No	0	9	7
891	G.h3s5.02	G.h3s5.03	2.53333	No	No	0	4	7
892	b.b25x5	b.lhb1x8	2.5	No	No	0	4	2
893	8x54	8x58	2.5	No	No	0	6	6
894	b.1x11	g.h1x12	2.49333	No	No	0	8	6
895	G.H5.20	G.H5.26	2.48333	No	No	0	8	8
896	I1x48	I1x51	2.47667	No	No	0	6	6
897	5x61	5x65	2.46333	No	No	0	8	8
898	7x54	8x48	2.45667	No	Yes	0	7	4
899	b.l27x2	b.l2x4	2.45333	No	No	0	1	5
900	b.b24x5	b.b25x5	2.45333	No	No	0	5	4
901	b.b3x5	b.b6x3	2.41	No	No	0	9	8
902	G.HN.42	G.HN.45	2.39667	No	No	0	5	4
903	5x68	G.H5.13	2.38333	No	No	0	0	8
904	g.ctx13	g.ctx9	2.37667	No	No	0	0	0
905	3x54	G.H5.20	2.37667	No	No	0	8	8
906	3x54	G.H5.16	2.36	No	No	0	8	6
907	1x56	8x53	2.35333	Yes	No	0	8	6
908	2x46	3x43	2.35333	Yes	No	0	9	8
909	1x55	1x56	2.34667	No	Yes	0	4	8
910	b.lhb1x10	b.lhb1x8	2.33667	No	No	0	4	2
911	G.HN.52	G.hns1.03	2.33667	No	No	0	3	5
912	b.l2x2	b.l6x2	2.33333	No	No	0	1	6
913	G.H4.04	G.hgh4.16	2.33	No	No	0	4	0
914	b.b5x3	b.l1x2	2.32667	Yes	No	0	9	9
915	G.s1h1.06	G.s5hg.01	2.32333	No	Yes	0	9	9
916	3x34	4x53	2.31333	No	No	0	5	8
917	4x38	4x40	2.31333	No	No	0	7	4
918	b.b16x3	b.b19x2	2.31	No	Yes	0	6	6
919	1x36	2x62	2.31	No	No	0	6	6
920	b.l27x6	g.ctx16	2.31	No	Yes	0	7	0
921	b.b10x4	b.b6x4	2.30667	Yes	No	0	6	7
922	1x46	2x54	2.30667	No	No	0	8	6
923	2x49	3x39	2.28	No	No	0	8	9
924	b.b7x5	b.l9x7	2.28	No	Yes	0	9	7
925	8x48	8x52	2.26333	Yes	No	0	4	4
926	6x29	G.H5.26	2.26333	No	No	0	5	8
927	6x43	6x47	2.25333	No	No	0	6	8
928	4x38	4x41	2.22667	No	No	0	7	4
929	4x38	G.hns1.02	2.19667	No	No	0	7	4
930	5x49	5x50	2.18667	No	No	0	5	9
931	b.1x4	g.h1x5	2.18667	No	No	0	0	6
932	b.b15x1	b.l16x1	2.18333	Yes	No	0	9	4
933	b.h2x4	b.lh12x3	2.16667	No	No	0	3	4
934	1x55	8x57	2.16	No	No	0	4	4
935	1x35	7x36	2.16	No	No	0	4	5
936	6x32	7x55	2.15333	No	No	0	8	6
937	2x53	3x35	2.14667	No	No	0	7	8
938	1x51	2x51	2.14333	No	No	0	4	7
939	G.H4.03	G.HG.08	2.14	Yes	No	0	4	7
940	G.HG.10	G.HG.12	2.14	No	No	0	5	0
941	1x43	2x59	2.13667	No	No	0	6	8
942	b.b16x2	b.l17x1	2.13333	No	No	0	5	2
943	1x43	2x58	2.11333	No	No	0	6	7
944	G.H4.04	G.hgh4.10	2.09333	No	No	0	4	1
945	b.b12x2	b.l13x1	2.09333	No	No	0	7	2
946	G.hgh4.17	G.hgh4.18	2.09333	No	No	0	0	1
947	3x42	4x49	2.06667	No	No	0	8	7
948	G.s3h2.01	G.s3h2.02	2.05667	No	No	0	9	9
949	6x40	7x52	2.05	No	No	0	7	8
950	5x63	5x67	2.02333	No	No	0	3	0
951	b.1x10	g.h1x12	2.02	No	No	0	0	6
952	7x52	7x53	2.01667	No	Yes	0	8	9
953	b.b18x5	b.l18x4	2.01	Yes	No	0	5	7
954	1x60	8x56	1.99	No	No	0	5	3
955	4x48	4x52	1.98667	No	No	0	3	4
956	g.ctx14	g.ctx9	1.97333	Yes	No	0	0	0
957	g.h2x14	g.h2x15	1.95	No	No	0	4	6
958	G.hgh4.04	G.hgh4.07	1.93667	No	No	0	6	2
959	b.b17x2	g.h1x10	1.92667	No	No	0	3	9
960	5x41	6x56	1.90333	No	No	0	5	5
961	b.1x12	g.h1x11	1.88	No	Yes	0	6	9
962	G.H5.01	G.H5.02	1.88	No	No	0	9	4
963	3x21	E1x50	1.87333	No	Yes	0	8	8
964	6x26	6x27	1.86333	No	No	0	4	2
965	b.1x22	g.l1x4	1.86	No	Yes	0	3	8
966	2x55	2x56	1.85	No	No	0	4	5
967	b.b10x5	b.b7x3	1.84667	Yes	No	0	9	9
968	b.1x14	g.l1x4	1.84333	No	Yes	0	4	8
969	G.H1.03	G.s1h1.06	1.82	No	No	0	9	9
970	b.b12x1	b.l13x5	1.82	No	No	0	6	5
971	b.b13x1	b.l12x3	1.82	No	No	0	4	5
972	G.HN.48	G.HN.51	1.81	No	No	0	4	4
973	8x49	I1x49	1.77667	No	No	0	6	5
974	b.1x6	b.1x7	1.77333	No	No	0	0	0
975	G.S2.02	G.hfs2.06	1.76	No	No	0	5	0
976	g.ctx7	g.ctx8	1.75	No	No	0	0	0
977	b.b16x4	b.l13x2	1.74333	Yes	No	0	6	6
978	G.H4.06	G.HG.08	1.7	No	No	0	8	7
979	2x38	4x39	1.69667	Yes	No	0	6	2
980	G.hfs2.07	b.l7x4	1.69667	No	No	0	8	9
981	G.h4s6.10	G.h4s6.11	1.67667	No	No	0	0	0
982	G.s3h2.02	G.s3h2.03	1.64333	No	Yes	0	9	9
983	b.b25x4	b.lhb1x9	1.62333	No	No	0	4	3
984	b.b20x1	b.l21x5	1.62333	No	No	0	5	4
985	b.1x4	g.h1x4	1.57667	No	No	0	0	0
986	b.b23x2	b.l24x1	1.57667	Yes	No	0	6	5
987	1x47	2x51	1.56	No	No	0	6	7
988	3x41	5x46	1.56	No	No	0	5	4
989	G.H1.02	G.S2.01	1.54667	No	No	0	9	9
990	G.S2.01	G.S3.08	1.53667	No	No	0	9	9
991	5x34	5x38	1.53667	Yes	No	0	1	4
992	b.1x4	g.h1x8	1.52	No	No	0	0	7
993	b.b12x6	b.l9x2	1.41	Yes	No	0	8	5
994	8x52	8x55	1.41	No	No	0	4	5
995	G.H3.13	G.h4s6.09	1.40667	Yes	No	0	6	0
996	G.H3.01	G.s1h1.02	1.38	Yes	No	0	9	8
997	G.H5.18	G.H5.22	1.36	No	No	0	3	4
998	6x28	6x31	1.35667	No	No	0	4	5
999	G.HN.29	G.HN.33	1.35667	No	No	0	0	4
1000	G.HN.32	G.HN.34	1.35	No	No	0	6	4
1001	5x55	5x59	1.32	No	No	0	4	3
1002	G.HN.31	G.HN.32	1.31333	No	No	0	3	6
1003	b.l9x1	b.l9x2	1.3	No	No	0	5	5
1004	b.l25x1	b.l25x2	1.3	No	No	0	3	5
1005	G.hgh4.12	G.hgh4.13	1.3	No	No	0	0	0
1006	b.lhb1x6	b.lhb1x7	1.22667	Yes	No	0	3	1
1007	5x55	6x41	1.22667	No	No	0	4	8
1008	G.s6h5.02	G.s6h5.03	1.14667	No	No	0	8	9
1009	5x38	5x42	1.14	No	No	0	4	4
1010	6x23	6x25	1.12333	No	No	0	0	0
1011	G.hgh4.19	G.hgh4.20	1.09333	No	Yes	0	7	3
1012	b.1x15	g.h1x15	1.08333	No	No	0	7	8
1013	G.s6h5.03	G.s6h5.04	1.07667	No	No	0	9	9
1014	g.h2x3	g.h2x6	1.07	No	No	0	5	2
1015	4x44	4x48	1.06667	No	No	0	3	3
1016	1x40	1x44	1.06	No	No	0	4	4
1017	b.1x8	g.h1x8	1.03667	No	No	0	0	7
1018	1x44	1x48	1.02333	No	No	0	4	4
1019	1x41	1x42	1.02333	No	No	0	5	7
1020	5x59	5x63	1.01333	No	No	0	3	3
1021	b.b20x6	b.l17x2	1.00333	Yes	No	0	6	6
1022	4x51	4x55	0.993333	No	No	0	3	4
1023	g.ctx6	g.ctx7	0.98	Yes	No	0	0	0
1024	b.b16x1	b.l17x3	0.973333	No	Yes	0	4	9
1025	6x30	6x35	0.96	No	No	0	7	6
1026	b.b28x6	b.l25x2	0.936667	Yes	No	0	9	5
1027	b.b28x1	b.l1x3	0.926667	No	Yes	0	4	9
1028	1x31	1x34	0.886667	Yes	No	0	2	4
1029	b.1x3	b.1x6	0.85	No	No	0	0	0
1030	G.H1.06	G.H1.09	0.826667	No	No	0	9	8
1031	G.H2.01	G.H2.02	0.793333	No	No	0	9	8
1032	G.HG.10	G.HG.11	0.65	No	No	0	5	0
1033	b.l8x3	b.l8x6	0.606667	No	No	0	0	0
1034	g.ctx10	g.ctx12	0.593333	No	No	0	0	0
1035	G.h4s6.04	G.h4s6.08	0.57	No	No	0	4	5
1036	6x38	6x42	0.546667	No	No	0	5	4
1037	6x46	6x47	0.546667	No	No	0	5	8
1038	G.h4s6.02	G.h4s6.03	0.533333	No	No	0	7	4
1039	4x40	4x44	0.53	No	No	0	4	3
1040	G.HN.53	G.S1.01	0.53	No	No	0	2	7
1041	6x39	6x43	0.53	No	No	0	5	6
1042	4x55	4x56	0.526667	No	No	0	4	5
1043	5x45	5x46	0.526667	No	No	0	4	4
1044	g.ctx6	g.h2x16	0.526667	Yes	No	0	0	4
1045	G.hfs2.05	b.l9x4	0.523333	No	No	0	0	5
1046	G.hgh4.11	G.hgh4.12	0.523333	No	No	0	5	0
1047	G.H3.11	G.H3.12	0.516667	No	No	0	8	8
1048	G.HG.12	G.HG.13	0.51	No	No	0	0	7
1049	g.h1x2	g.h1x3	0.506667	No	No	0	0	0
1050	1x34	1x37	0.49	No	No	0	4	5
1051	g.l1x1	g.l1x2	0.473333	No	Yes	0	1	2
1052	b.lhb1x3	b.lhb1x4	0.466667	Yes	No	0	2	1
1053	b.l24x3	b.lhb1x1	0.466667	No	No	0	5	1
1054	3x22	3x23	0.46	No	No	0	3	3
1055	b.lhb1x1	b.lhb1x2	0.453333	No	No	0	1	1
1056	G.S2.07	G.s2s3.02	0.453333	No	No	0	3	4
1057	g.h1x13	g.h1x9	0.45	No	No	0	1	6
1058	b.l21x3	b.l21x4	0.45	No	No	0	3	4
1059	G.HG.03	G.HG.06	0.443333	Yes	No	0	6	6
1060	b.1x14	b.1x17	0.436667	No	No	0	4	2
1061	b.l8x4	b.l8x5	0.386667	No	No	0	0	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: hub id, click on each number to highlight the corresponding hub in the 3D visualization.

Hub: the hub being considered.

Avg Int. Strength: the average interaction strength of all the links of the corresponding hub.

Num Of Links: the number of links of the corresponding hub.

Community: the id of the community the link belong to, otherwise 0.

ConSurf: this column reports the ConSurf conservation grades of each hub.

Index	Hub	Avg. Int. Strength	Num. Of Links	Community	ConSurf
1	G.H1.01	6.63667	4	16	9
2	G.S3.03	5.59111	6	3	8
3	G.S3.04	10.4575	4	14	7
4	G.S3.06	9.95417	4	14	7
5	G.s3h2.03	5.09467	5	2	9
6	G.H2.05	5.95583	4	2	8
7	G.H2.06	5.02611	6	2	9
8	G.H2.07	7.168	5	0	9
9	G.h2s4.01	7.95417	4	0	9
10	G.S4.07	6.55667	4	0	8
11	G.H3.01	7.17167	4	0	9
12	G.H3.09	4.485	6	10	9
13	G.H3.13	7.575	6	10	6
14	G.H3.17	8.90222	6	2	5
15	G.S5.03	4.7425	4	8	9
16	G.S5.04	4.375	4	10	9
17	G.S5.05	5.01933	5	8	9
18	G.s5hg.01	6.27333	4	0	9
19	G.HG.01	6.4925	4	7	6
20	G.HG.03	4.38917	4	0	6
21	G.hgh4.05	11.3533	4	0	6
22	G.hgh4.20	3.845	4	0	3
23	G.hgh4.21	7.32167	4	0	4
24	G.H4.03	2.9225	4	0	4
25	G.H4.08	5.43556	6	7	3
26	G.H4.10	8.92533	5	0	7
27	G.H4.12	6.66917	4	7	4
28	G.H4.15	7.84083	4	10	8
29	G.S6.02	8.73833	4	0	8
30	G.S6.05	7.84867	5	7	5
31	G.H5.03	5.89917	4	8	9
32	G.H5.06	7.16417	4	8	4
33	G.H5.08	6.03778	6	3	8
34	G.H5.23	7.72	4	3	4
35	b.lhb1x3	3.7125	4	0	2
36	b.lhb1x6	4.93167	4	18	3
37	b.b1x4	5.11667	4	9	7
38	b.l1x3	8.60733	5	0	9
39	b.l1x6	8.95933	5	2	9
40	b.b2x1	10.008	5	2	8
41	b.b2x5	7.402	5	0	7
42	b.b3x3	3.85867	5	6	8
43	b.l3x1	9.69333	4	2	9
44	b.b4x3	4.48917	4	6	7
45	b.b4x6	10.464	5	0	9
46	b.l4x1	3.84667	4	9	5
47	b.l4x2	10.785	4	9	4
48	b.b5x2	6.41667	4	0	7
49	b.b5x3	6.50733	5	15	9
50	b.b5x5	4.85833	4	6	5
51	b.b5x7	4.525	4	0	7
52	b.l5x1	4.456	5	6	8
53	b.l5x5	8.54267	5	0	9
54	b.b6x1	4.342	5	2	9
55	b.b6x5	4.45667	5	6	6
56	b.l6x5	6.655	4	20	4
57	b.b7x1	5.49333	5	20	4
58	b.l7x2	3.94	4	2	9
59	b.b8x4	4.898	5	6	6
60	b.l9x3	5.13778	6	2	9
61	b.l9x6	5.18407	9	2	8
62	b.l9x7	3.57667	5	2	7
63	b.b10x3	4.05067	5	2	8
64	b.b10x4	5.775	4	0	6
65	b.b10x5	3.6	5	0	9
66	b.b11x2	4.15833	4	0	7
67	b.b11x4	6.4675	4	2	9
68	b.b11x6	5.81833	4	2	9
69	b.l11x2	7.225	4	2	9
70	b.b12x3	3.60167	4	5	8
71	b.b12x6	7.34095	7	2	8
72	b.b13x7	8.03733	5	5	7
73	b.l13x3	8.07333	6	5	9
74	b.l13x7	4.58083	4	5	9
75	b.b15x1	7.07067	5	5	9
76	b.l15x2	6.905	4	5	9
77	b.b16x4	8.644	5	5	6
78	b.b16x5	3.54083	4	0	5
79	b.b16x6	8.23333	6	5	8
80	b.b16x7	7.94267	5	13	9
81	b.b17x5	7.85333	4	4	7
82	b.b17x7	8.46917	4	4	8
83	b.l17x3	7.79714	7	4	9
84	b.l17x6	6.75333	5	2	9
85	b.b18x3	5.2225	4	4	8
86	b.b18x5	5.51333	4	0	5
87	b.l18x1	6.19889	6	12	6
88	b.l18x2	5.53417	4	12	7
89	b.b19x2	7.77	5	4	6
90	b.b19x4	5.06	4	4	8
91	b.l19x2	8.10917	4	4	9
92	b.b20x2	6.285	4	4	6
93	b.b20x4	9.454	5	4	8
94	b.b20x6	6.01056	6	4	6
95	b.b20x7	5.71667	4	0	9
96	b.l20x2	8.12333	4	0	9
97	b.b21x1	8.13	6	4	7
98	b.b21x5	5.88417	4	0	4
99	b.b21x7	6.35	5	0	5
100	b.b22x5	5.08667	5	12	7
101	b.l22x5	7.34733	5	18	9
102	b.b23x2	4.10067	5	12	6
103	b.b23x6	6.37333	7	2	7
104	b.l23x1	6.198	5	2	6
105	b.b24x4	8.04083	4	0	6
106	b.l25x3	8.99067	5	11	9
107	b.l25x6	12.7167	5	2	8
108	b.l28x1	9.85143	7	2	9
109	b.b28x4	7.1175	4	11	6
110	b.b28x6	7.93067	5	11	9
111	g.h1x11	2.75333	4	0	9
112	g.l1x2	4.51583	4	4	2
113	g.l1x4	5.14833	6	4	8
114	g.ctx3	6.02667	5	0	9
115	NT	9.51818	11	1	4.4
116	1x31	5.34667	4	1	2
117	1x56	2.90167	4	0	8
118	2x38	5.28	4	3	6
119	2x39	5.95583	4	0	8
120	2x40	5.126	5	0	8
121	2x42	5.58067	5	0	7
122	2x46	4.41833	4	22	9
123	2x50	6.47867	5	22	9
124	2x57	4.71667	5	1	6
125	2x61	5.518	5	1	6
126	2x64	7.09417	4	1	4
127	2x68	6.51333	4	1	4
128	E1x50	8.11	4	0	8
129	E1x52	7.48	4	1	7
130	3x24	5.29417	4	1	5
131	3x28	6.01389	6	1	5
132	3x31	5.24	4	1	4
133	3x33	5.08583	4	1	5
134	3x37	6.9725	4	0	7
135	3x55	7.15833	4	3	7
136	I2	6.096	15	3	5.83333
137	4x42	4.57667	4	3	7
138	4x61	5.624	5	1	6
139	E2	13.1556	15	1	3.2
140	5x34	3.59083	4	1	1
141	5x39	6.61267	5	1	6
142	5x47	6.81417	4	0	8
143	5x58	5.87933	5	0	9
144	6x48	6.02611	6	1	8
145	6x51	6.87333	6	1	7
146	6x52	6.17333	4	0	7
147	6x54	8.222	5	1	4
148	6x55	8.2475	4	1	6
149	E3	8.042	10	1	2.71429
150	7x34	7.95667	5	1	5
151	7x38	5.13133	5	1	5
152	7x53	4.47667	4	0	9
153	8x48	3.96083	4	0	4
154	8x50	3.708	5	17	9
155	Lig	11.1535	21	1	0
156	g.ctx6	2.65667	4	0	0
157	g.ctx14	5.1725	4	9	0
158	g.ctx16	3.96952	7	9	0

Color	ConSurf Grade
	No Conservation data available
	1
	2
	3
	4
	5
	6
	7
	8
	9

All columns can be sorted in ascending/descending alphabetical order, clicking on the corresponding column header.

Index: link id, click on each number to highlight the corresponding link in the 3D visualization.

Node1 Node2: the two nodes of the corresponding link.

Recurrence: the relative Recurrence in the pool of shortest paths.

Strength: the interaction strength between the two nodes.

Hub1?, Hub2?: "Yes" if the corresponding node has more than 3 links, otherwise "No".

Community: the id of the community the link belong to, otherwise 0.

ConSurf1, ConSurf2: these columns report the ConSurf conservation grades of the two nodes involved in a link.

Index	Node1	Node2	Recurrence	Int. Strength	Hub1?	Hub2?	Community	ConSurf1	ConSurf2
1	b.b3x4	b.b4x6	50.0706	5.76333	No	Yes	0	9	9
2	b.b3x4	b.l1x3	50.1402	5.11333	No	Yes	0	9	9
3	b.b3x6	b.l1x3	100	15.3433	No	Yes	0	9	9
4	b.b3x6	b.l3x2	99.9587	8.34	No	No	0	9	9
5	b.b4x4	b.b4x6	49.9778	14.0933	No	Yes	0	8	9
6	b.b4x4	b.l1x3	49.9835	13.7	No	Yes	0	8	9
7	b.l1x4	b.l3x2	99.7506	11.31	No	No	0	6	9
8	G.HN.51	b.l1x4	99.7087	5.17	No	No	0	4	6
9	G.HN.51	G.hns1.02	99.6246	6.18667	No	No	0	4	4
10	b.b3x2	b.b4x6	98.6212	4.17667	No	Yes	0	5	9
11	b.b2x5	b.b3x2	98.5607	11.0067	Yes	No	0	7	5
12	b.b2x3	b.b2x5	91.2278	5.42667	No	Yes	0	6	7
13	b.b26x2	b.b2x3	91.0844	5.4	No	No	0	7	6
14	b.b26x1	b.b26x2	91.0125	3.44	No	No	0	9	7
15	b.b26x1	b.l28x1	90.9406	4.53	No	Yes	0	9	9
16	b.b2x1	b.l28x1	42.952	9.32333	Yes	Yes	2	8	9
17	G.hns1.02	I2	99.3331	3.36	No	Yes	3	4	5.83333
18	G.S5.07	G.s5hg.01	12.8612	5.13	No	Yes	0	9	9
19	G.HG.07	G.s4h3.02	20.0588	4.08	No	No	0	9	9
20	G.HG.07	G.s4h3.04	20.7957	9.15667	No	No	0	9	4
21	G.HG.15	G.s4h3.04	21.2384	11.2833	No	No	0	7	4
22	G.HG.15	G.hgh4.05	21.3901	7.95333	No	Yes	0	7	6
23	G.H4.10	G.hgh4.05	27.3235	16.4333	Yes	Yes	0	7	6
24	G.H4.10	G.H4.14	28.0093	9.71667	Yes	No	0	7	5
25	G.H3.06	G.H4.14	28.4591	3.98	No	No	0	6	5
26	G.H3.06	G.H4.15	29.3844	11.3633	No	Yes	0	6	8
27	G.H3.09	G.H4.15	26.3788	6.07333	Yes	Yes	10	9	8
28	G.H3.09	G.H3.13	23.5323	4.34333	Yes	Yes	10	9	6
29	G.H3.13	G.h4s6.13	24.5358	22.9233	Yes	No	0	6	7
30	G.h4s6.12	G.h4s6.13	24.6597	3.38667	No	No	0	2	7
31	G.h3s5.01	G.h4s6.12	25.0176	3.55333	No	No	0	3	2
32	G.H3.16	G.h3s5.01	25.1441	3.55333	No	No	0	5	3
33	G.H3.16	G.H3.17	25.2711	14.33	No	Yes	0	5	5
34	G.H3.17	b.l28x1	33.3212	3.12667	Yes	Yes	2	5	9
35	G.HG.03	G.s4h3.02	11.432	6.00667	Yes	No	0	6	9
36	b.b6x1	b.l9x6	36.6504	5.18667	Yes	Yes	2	9	8
37	b.b2x1	b.b6x1	38.6972	3.19333	Yes	Yes	2	8	9
38	b.l25x6	b.l28x1	11.9944	18.3267	Yes	Yes	2	8	9
39	G.H3.17	b.l23x1	10.418	5.21333	Yes	Yes	2	5	6
40	G.H5.23	I2	44.9185	4.8	Yes	Yes	3	4	5.83333
41	2x39	2x40	89.1918	4.38333	Yes	Yes	0	8	8
42	2x39	G.H5.23	44.9558	12.0667	Yes	Yes	0	8	4
43	2x37	2x39	44.7485	3.14	No	Yes	0	7	8
44	2x37	I2	44.8234	3.44	No	Yes	3	7	5.83333
45	2x40	2x43	13.6903	3.27333	Yes	No	0	8	8
46	b.b11x6	b.l9x6	42.9596	3.39	Yes	Yes	2	9	8
47	b.b11x6	b.l9x3	42.1562	9.3	Yes	Yes	2	9	9
48	b.l9x3	b.l9x7	17.4488	3.85667	Yes	Yes	2	9	7
49	b.b10x3	b.l9x7	17.0337	3.17333	Yes	Yes	2	8	7
50	b.b10x3	b.b6x2	34.097	3.38	Yes	No	0	8	8
51	b.b10x4	b.b6x2	33.8128	4.31	Yes	No	0	6	8
52	b.b10x2	b.b10x4	32.9597	5.57333	No	Yes	0	6	6
53	b.b10x2	b.b14x3	32.6751	5.82	No	No	0	6	5
54	b.b11x3	b.b14x3	32.3905	4.96667	No	No	0	5	5
55	b.b11x3	b.b15x1	32.1057	6.11667	No	Yes	0	5	9
56	b.b15x1	b.b16x6	28.0566	12.36	Yes	Yes	5	9	8
57	b.b11x4	b.l9x3	17.1613	5.93667	Yes	Yes	2	9	9
58	b.b10x3	b.b11x4	17.0606	5.63333	Yes	Yes	2	8	9
59	b.b16x6	b.b17x3	18.5236	4.78667	Yes	No	5	8	5
60	b.b17x3	g.h1x10	18.2653	4.57667	No	No	0	5	9
61	b.b17x2	g.h1x10	17.7774	1.92667	No	No	0	3	9
62	b.b17x2	b.l16x3	17.4873	4.96	No	No	0	3	3
63	b.b17x4	b.l16x3	15.7315	7.75333	No	No	13	5	3
64	b.b16x5	b.b17x4	15.4513	3.23667	Yes	No	0	5	5
65	b.b16x5	b.b17x5	14.8818	3.54667	Yes	Yes	0	5	7
66	b.l21x7	b.l23x1	17.0125	2.59667	No	Yes	2	5	6
67	b.b23x6	b.l21x7	16.2422	3.58333	Yes	No	2	7	5
68	b.b23x6	b.b24x6	12.9123	5.79	Yes	No	0	7	8
69	b.b21x7	b.b24x6	12.4147	8.04	Yes	No	0	5	8
70	1x57	2x40	73.4359	6.13333	No	Yes	0	7	8
71	1x57	2x44	73.2555	4.60667	No	No	0	7	6
72	1x54	2x44	73.075	2.55	No	No	0	7	6
73	1x54	2x48	72.7136	3.85333	No	No	0	7	6
74	2x48	2x52	72.5328	5.28667	No	No	0	6	6
75	2x52	3x31	72.3519	3.15667	No	Yes	0	6	4
76	3x31	3x32	70.0404	5.29667	Yes	No	1	4	6
77	2x57	3x32	38.2897	5.97667	Yes	No	1	6	6
78	2x57	Lig	30.0397	3.42333	Yes	Yes	1	6	0
79	Lig	NT	13.2489	14.7667	Yes	Yes	1	0	4.4
80	3x28	3x32	31.5699	4.57667	Yes	No	1	5	6
81	3x28	Lig	30.0821	3.85	Yes	Yes	1	5	0
82	E2	Lig	12.7105	18.3033	Yes	Yes	1	3.2	0
83	b.b2x5	b.l4x1	10.1285	4.53	Yes	Yes	0	7	5

Download PSN data

2D representation of the global metapath, ligand(s) interactions and
histograms of path distribution according to several parameters
(click on the image to enlarge it 🔍):

A 2D representation of the global communication in the network.

ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Number of shortest communication paths as a function of the average residue correlation.

Number of shortest communication paths as a function of the average interaction strength of their links.

Number of shortest communication paths as a function of the % of hub nodes in each path.

Number of shortest communication paths as a function of the number of nodes in each path.

Number of shortest communication paths as a function of the % of correlated nodes in each path.

2D representation of the interactions of this orthosteric/allosteric ligand.

Links and nodes colored according to ConSurf Conservation Grade (See documentation):

n/a 1 2 3 4 5 6 7 8 9

Node1	Node2	LinkStrength	Comm	IsNode1Hub?	IsNode2Hub?	Node1Cons	Node2Cons	Node1Shell	Node2Shell
NT	NT	15.7733	1	Yes	Yes	4.4	4.4	1	1
E2	NT	11.3033	1	Yes	Yes	3.2	4.4	1	1
E3	NT	4.97333	1	Yes	Yes	2.71429	4.4	1	1
Lig	NT	14.7667	1	Yes	Yes	0	4.4	0	1
2x68	NT	6.6	1	Yes	Yes	4	4.4	1	1
7x31	NT	16.6567	1	No	Yes	4	4.4	1	1
2x67	NT	5.07333	1	No	Yes	5	4.4	2	1
1x31	NT	3.84	1	Yes	Yes	2	4.4	2	1
1x32	NT	6.47333	1	No	Yes	3	4.4	2	1
7x32	NT	3.46667	1	No	Yes	1	4.4	2	1
2x57	2x61	6.81333	1	Yes	Yes	6	6	1	1
2x57	3x28	3.82667	1	Yes	Yes	6	5	1	1
2x57	3x32	5.97667	1	Yes	No	6	6	1	2
2x57	7x38	3.54333	1	Yes	Yes	6	5	1	2
2x60	3x24	6.87333	1	No	Yes	5	5	2	2
2x60	3x28	11.8867	1	No	Yes	5	5	2	1
2x61	3x28	8.12	1	Yes	Yes	6	5	1	1
2x61	7x34	5.04	1	Yes	Yes	6	5	1	1
2x61	7x38	3.27333	1	Yes	Yes	6	5	1	2
2x61	Lig	4.34333	1	Yes	Yes	6	0	1	0
2x64	2x68	3.49	1	Yes	Yes	4	4	1	1
2x64	E1x50	6.75333	1	Yes	Yes	4	8	1	2
2x64	E2	9.59333	1	Yes	Yes	4	3.2	1	1
2x64	Lig	8.54	1	Yes	Yes	4	0	1	0
2x68	E2	7.10333	1	Yes	Yes	4	3.2	1	1
2x68	Lig	8.86	1	Yes	Yes	4	0	1	0
E1x50	E2x50	9.14333	0	Yes	No	8	9	2	1
3x22	E2	5.89333	1	No	Yes	3	3.2	2	1
3x24	3x28	3.82333	1	Yes	Yes	5	5	2	1
3x25	4x65	3.44	1	No	No	9	5	2	2
3x25	E2	5.64667	1	No	Yes	9	3.2	2	1
3x25	E2x50	4.85333	1	No	No	9	9	2	1
3x28	3x32	4.57667	1	Yes	No	5	6	1	2
3x29	4x65	5.96	1	No	No	5	5	1	2
3x29	Lig	3.66333	1	No	Yes	5	0	1	0
3x33	3x37	5.02	1	Yes	Yes	5	7	1	2
3x33	4x57	3.25	1	Yes	No	5	7	1	2
3x33	4x61	3.66	1	Yes	Yes	5	6	1	1
3x33	Lig	8.41333	1	Yes	Yes	5	0	1	0
4x61	E2x52	5.58667	1	Yes	No	6	4	1	2
4x61	5x39	9.02	1	Yes	Yes	6	6	1	2
4x61	Lig	5.89333	1	Yes	Yes	6	0	1	0
4x64	E2	12.93	1	No	Yes	5	3.2	2	1
E2	E2	39.6	1	Yes	Yes	3.2	3.2	1	1
E2	Lig	18.3033	1	Yes	Yes	3.2	0	1	0
E2x50	Lig	3.74667	1	No	Yes	9	0	1	0
E2x51	Lig	8.45667	0	No	Yes	4	0	1	0
E2	E2x52	9.00667	1	Yes	No	3.2	4	1	2
5x36	E2	12.0433	1	No	Yes	4	3.2	2	1
5x39	E2	7.07333	1	Yes	Yes	6	3.2	2	1
5x31	E2	6.61	0	No	Yes	1	3.2	2	1
5x34	E2	5.53667	1	Yes	Yes	1	3.2	2	1
5x35	E2	7.09	1	No	Yes	4	3.2	2	1
5x34	5x35	3.51333	1	Yes	No	1	4	2	2
5x39	5x40	6.53333	1	Yes	No	6	5	2	2
5x40	6x55	4.14667	0	No	Yes	5	6	2	1
6x48	6x51	8.3	1	Yes	Yes	8	7	2	1
6x48	7x41	5.18667	1	Yes	No	8	7	2	2
6x51	6x52	5.92	1	Yes	Yes	7	7	1	2
6x51	6x55	11.2867	1	Yes	Yes	7	6	1	1
6x51	7x38	3.79333	1	Yes	Yes	7	5	1	2
6x51	7x41	5.01667	1	Yes	No	7	7	1	2
6x51	Lig	6.92333	1	Yes	Yes	7	0	1	0
6x54	6x55	7.10333	1	Yes	Yes	4	6	2	1
6x54	E3	10.25	1	Yes	Yes	4	2.71429	2	1
6x54	7x30	6.57	1	Yes	No	4	4	2	1
6x54	7x34	12.16	1	Yes	Yes	4	5	2	1
6x55	Lig	10.4533	1	Yes	Yes	6	0	1	0
6x57	E3	5.09333	0	No	Yes	4	2.71429	2	1
6x58	E3	12.13	0	No	Yes	4	2.71429	2	1
6x61	E3	4.72333	1	No	Yes	4	2.71429	2	1
E3	E3	11.8733	1	Yes	Yes	2.71429	2.71429	1	1
7x30	E3	4.03	1	No	Yes	4	2.71429	1	1
E3	Lig	8.37	1	Yes	Yes	2.71429	0	1	0
7x30	Lig	4.18667	1	No	Yes	4	0	1	0
7x31	7x32	3.84	1	No	No	4	1	1	2
7x31	Lig	6.63667	1	No	Yes	4	0	1	0
7x34	7x38	8.22667	1	Yes	Yes	5	5	1	2
7x34	Lig	11.6867	1	Yes	Yes	5	0	1	0
3x29	4x61	3.96	1	No	Yes	5	6	1	1
7x29	E3	7.10333	1	No	Yes	3	2.71429	2	1
7x28	Lig	3.22667	0	No	Yes	0	0	1	0
2x57	Lig	3.42333	1	Yes	Yes	6	0	1	0
3x28	Lig	3.85	1	Yes	Yes	5	0	1	0
2x65	7x34	2.67	0	No	Yes	5	5	2	1

Location and physicochemical properties of the interaction partners of this ligand

Interactions of this ligand

Similarities between the interactions of this ligand and those of other networks

Similarity	Network Type	Name	Ligand	Description
90.00	Consensus	tachykinin_on	Orthosteric Ligand	nk1_on nk2_on
89.47	Single	7RMH	Substance P	7RMH-NK₁-Substance P-Gs/&β;1/&γ;2
84.21	Single	7RMG	Substance P	7RMG-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
84.21	Consensus	nk1_on	Orthosteric Ligand	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2 7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
81.82	Single	7P02	Protachykinin-1	7P02-NK₁-Protachykinin-1-chim(NtGi1-Gs)/&β;1/&γ;2
78.95	Single	7P00	Substance P	7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
76.19	Single	7RMI	Substance P	7RMI-NK₁-Substance P-chim(Gs-CtGq)/&β;1/&γ;2
73.68	Single	8U26	Protachykinin-1	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2
66.67	Single	8JBF	Senktide	8JBF-NK₃-Senktide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
52.38	Single	7XWO	Neurokinin-A	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
47.83	Consensus	nk2_on	Orthosteric Ligand	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
43.48	Single	6OSA	JMV449	6OSA-NTS₁-JMV449-Gi1/&β;1/&γ;2
43.33	Consensus	gs_peptide	Orthosteric Ligand	gs_cck gs_motilin gs_neuromedin gs_orexin gs_sst gs_tachykinin gs_trh gs_vasopressin-ot gs_bombesin gs_bradykinin gs_compl-peptide gs_endothelin gs_galanin gs_ghrelin gs_melanocortin
42.86	Single	7F9Y	Ghrelin-28	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
42.31	Single	8IBV	Motilin	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
41.38	Single	8H0P	NMB30	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
41.38	Consensus	bb1_on	Orthosteric Ligand	8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
40.91	Single	8FN1	Neurotensin/neuromedin N	8FN1-NTS₁-Neurotensin/neuromedin N-chim(NtGi1-Go)/&β;1/&γ;2
40.91	Single	8JPC	Neurotensin 8-13	8JPC-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
40.00	Single	7XK8	Neuromedin-U-25	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
40.00	Single	7YOO	Neuropeptide Y	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
40.00	Consensus	gs_bombesin	Orthosteric Ligand	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8H0P-BB₁-NMB30-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
39.13	Single	3ZEV	Neurotensin	3ZEV-NTS₁-Neurotensin
39.13	Single	7L0P	Neurotensin	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
39.13	Single	7L0Q	Neurotensin	7L0Q-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
39.13	Single	8FMZ	Neurotensin/neuromedin N	8FMZ-NTS₁-Neurotensin/neuromedin N-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
38.71	Consensus	gq_peptide	Orthosteric Ligand	gq_cck gq_angiotensin gq_bombesin gq_bradykinin
38.71	Consensus	peptide_on	Orthosteric Ligand	opioid_on angiotensin_on bombesin_on cck_on endothelin_on ghrelin_on npy_on nts_on orexin_on vasopressin-ot_on tachykinin_on sst_on relaxin_on trh_on nmur_on motilin_on melanocortin_on galanin_on fpr-alx_on compl-peptide_on bradykinin_on apelin_on
38.46	Single	7L0R	Neurotensin	7L0R-NTS₁-Neurotensin-Gi1/&β;1/&γ;1
38.46	Single	8GHV	PubChem 145964903	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
38.46	Consensus	nop_on	Orthosteric Ligand	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
38.10	Single	7XJJ	Galanin	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
38.10	Consensus	go_galanin	Orthosteric Ligand	7XJJ-GAL₁-Galanin-Go/&β;1/&γ;2
37.93	Single	8HK5	Complement C5	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2
37.50	Single	4GRV	Neurotensin 8-13	4GRV-NTS₁-Neurotensin 8-13
37.50	Single	4XEE	Neurotensin	4XEE-NTS₁-Neurotensin
37.50	Single	4XES	Neurotensin	4XES-NTS₁-Neurotensin
37.50	Consensus	gi_peptide	Orthosteric Ligand	gi_opioid gi_endothelin gi_formylpeptide gi_galanin gi_ghrelin gi_neuromedin gi_neurotensin gi_relaxin gi_neuropeptide gi_somatostatin gi_apelin gi_compl-peptide gi_cck
37.04	Consensus	alpha1_off	Orthosteric Ligand	alpha1a_off alpha1b_off
36.67	Consensus	gi_compl-peptide	Orthosteric Ligand	8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2 7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
36.67	Consensus	gi_neuromedin	Orthosteric Ligand	7XK8-NMUR2-Neuromedin-U-25-Gi1/&β;1/&γ;2
36.67	Consensus	kop_on	Orthosteric Ligand	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
36.36	Single	6Z4V	NTS8-13	6Z4V-NTS₁-NTS8-13
36.00	Single	4BUO	Neurotensin	4BUO-NTS₁-Neurotensin
36.00	Single	8JPF	Neurotensin	8JPF-NTS₁-Neurotensin-PubChem 118610427
36.00	Consensus	gi_neurotensin	Orthosteric Ligand	7L0P-NTS₁-Neurotensin-Gi1/&β;1/&γ;1 6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
35.71	Single	7F4H	Afamelanotide	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
35.71	Consensus	go_peptide	Orthosteric Ligand	go_opioid go_ghrelin go_compl-peptide go_galanin go_vasopressin
35.71	Consensus	gs_motilin	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
34.78	Single	6Z8N	SRI-9829	6Z8N-NTS₁-SRI-9829
34.62	Single	7NA7	Ghrelin-27	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2
34.62	Single	7RKF	Fractalkine	7RKF-US28-Fractalkine-GDP-chim(NtGi1-G11)/&β;1/&γ;2
34.62	Consensus	lpl_off	Orthosteric Ligand	s1p_off lpa_off
34.62	Consensus	lpl_on	Orthosteric Ligand	s1p_on lpa_on
34.48	Single	7YON	Peptide YY(3-36)	7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
34.48	Consensus	ghrelin_on	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
34.48	Consensus	nmur_on	Orthosteric Ligand	nmur1_on nmur2_on
34.29	Consensus	gi_neuropeptide	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2 7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2 7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
34.29	Consensus	mc2_on	Orthosteric Ligand	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
34.29	Consensus	npy1_on	Orthosteric Ligand	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
33.33	Single	4BV0	Neurotensin	4BV0-NTS₁-Neurotensin
33.33	Single	4BWB	Neurotensin	4BWB-NTS₁-Neurotensin
33.33	Single	4Z34	ONO-9780307	4Z34-LPA₁-ONO-9780307
33.33	Single	5XRA	AM11542	5XRA-CB₁-AM11542
33.33	Single	6IGK	Endothelin-3	6IGK-ET_B-Endothelin-3
33.33	Single	6UP7	Neurotensin	6UP7-NTS₁-Neurotensin-Arrestin2
33.33	Single	7F4I	SHU9119	7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
33.33	Single	7FEE	PubMed 104895	7FEE-CB₁-PubMed 104895-ZCZ011
33.33	Single	7WV9	PubMed 104895	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
33.33	Single	7X9B	Neuropeptide Y	7X9B-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2
33.33	Single	7Y64	C5a anaphylatoxin	7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
33.33	Single	8F7X	Nociceptin	8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2
33.33	Consensus	bb2_on	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
33.33	Consensus	bombesin_on	Orthosteric Ligand	bb2_on bb1_on
33.33	Consensus	c5a1_on	Orthosteric Ligand	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2 8HK5-C5a₁-Complement C5-Gi1/&β;1/&γ;2 7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2 7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2 7Y64-C5a₁-C5a anaphylatoxin-Gi1/&β;1/&γ;2
33.33	Consensus	gi_ghrelin	Orthosteric Ligand	7NA7-Ghrelin-Ghrelin-27-Gi1/&β;1/&γ;2 7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
33.33	Consensus	go_class-a	Orthosteric Ligand	go_amine go_peptide go_protein
33.33	Consensus	gq_bombesin	Orthosteric Ligand	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2 7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
33.33	Consensus	gs_ghrelin	Orthosteric Ligand	7F9Y-Ghrelin-Ghrelin-28-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Consensus	gs_neuromedin	Orthosteric Ligand	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
33.33	Consensus	lpa1_on	Orthosteric Ligand	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
33.33	Consensus	lpa_off	Orthosteric Ligand	lpa1_off
33.33	Consensus	lpa_on	Orthosteric Ligand	lpa1_on
33.33	Consensus	mc1_on	Orthosteric Ligand	7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2
32.35	Consensus	melanocortin_on	Orthosteric Ligand	mc2_on mc1_on mc3_on mc4_on mc5_on
32.26	Single	7W3Z	Gastrin Releasing Peptide	7W3Z-BB₂-Gastrin Releasing Peptide-chim(NtGi1L-Gq)/&β;1/&γ;2
32.26	Consensus	npy2_on	Orthosteric Ligand	7YOO-Y₂-Neuropeptide Y-Gi1/&β;1/&γ;2 7YON-Y₂-Peptide YY(3-36)-Gi1/&β;1/&γ;2
32.14	Single	7EZK	Cholecystokinin-8	7EZK-CCK_A-Cholecystokinin-8-chim(NtGi1-Gs)/&β;1/&γ;2
32.14	Consensus	gi_cck	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
32.14	Consensus	gi_lpl	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2 7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2 7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
32.00	Single	3VW7	Vorapaxar; Na	3VW7-PAR1-Vorapaxar; Na
32.00	Single	6KQI	PubMed 104895	6KQI-CB₁-PubMed 104895-ORG27569
32.00	Single	6YVR	NTS8-13	6YVR-NTS₁-NTS8-13
32.00	Single	7L0S	Neurotensin	7L0S-NTS₁-Neurotensin-Gi1/&β;1/γ1
32.00	Single	7L1U	Orexin	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
32.00	Single	7WQ4	Galanin	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
32.00	Single	7XJK	Galanin	7XJK-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
32.00	Single	7Y66	BM213	7Y66-C5a₁-BM213-Gi1/&β;1/&γ;2
32.00	Single	8H0Q	Gastrin Releasing Peptide	8H0Q-BB₂-Gastrin Releasing Peptide-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
32.00	Single	8IBU	Erythromycin A	8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
32.00	Single	8JPB	Neurotensin 8-13	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
32.00	Single	8WU1	KCA	8WU1-CB₁-KCA-Arrestin1
32.00	Consensus	cb1_off_allo	Orthosteric Ligand	6KQI-CB₁-PubMed 104895-ORG27569
32.00	Consensus	galanin_on	Orthosteric Ligand	gal2_on gal1_on
32.00	Consensus	lpa1_off	Orthosteric Ligand	4Z36-LPA₁-ONO-3080573 4Z34-LPA₁-ONO-9780307 4Z35-LPA₁-ONO-9910539 7YU4-LPA₁-ONO-0740556
31.82	Single	7C2E	PubChem 149050799	7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2
31.43	Single	6LRY	Sarafotoxin-B	6LRY-ET_B-Sarafotoxin-B
31.25	Single	7F4F	Afamelanotide	7F4F-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2
31.03	Single	6W25	SHU9119	6W25-MC₄-SHU9119-Ca
31.03	Single	7F4D	Alpha-MSH	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2
31.03	Single	7MBX	Cholecystokinin-8	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1
31.03	Single	7XOU	Cholecystokinin-8	7XOU-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;2
31.03	Consensus	opioid_on	Orthosteric Ligand	kop_on mop_on nop_on dop_on
30.77	Single	4Z35	ONO-9910539	4Z35-LPA₁-ONO-9910539
30.77	Single	6OS9	JMV449	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
30.77	Single	7EZH	Cholecystokinin-8	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2
30.77	Single	7YU8	ONO-0740556	7YU8-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
30.77	Single	8GUT	LEI-102	8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2
30.77	Consensus	gal2_on	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
30.77	Consensus	gs_galanin	Orthosteric Ligand	7WQ4-GAL₂-Galanin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
30.77	Consensus	s1p1_on	Orthosteric Ligand	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2 7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2 7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2 7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2 7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2 7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2 7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2 7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
30.56	Single	7X9A	Neuropeptide Y	7X9A-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
30.56	Consensus	npy_on	Orthosteric Ligand	npy2_on npy4_on npy1_on
30.43	Single	7LCI	Danuglipron	7LCI-GLP-1-Danuglipron-Gs/&β;1/&γ;2
30.43	Single	7V3Z	PubMed 104895	7V3Z-CB₁-PubMed 104895
30.43	Single	7WQ3	Galanin	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
30.43	Single	7YU4	ONO-0740556	7YU4-LPA₁-ONO-0740556
30.43	Consensus	cb1_on_allo	Orthosteric Ligand	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
30.43	Consensus	gal1_on	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
30.43	Consensus	gi_galanin	Orthosteric Ligand	7WQ3-GAL₁-Galanin-Gi1/&β;1/&γ;2
30.30	Single	7VGX	Neuropeptide Y	7VGX-Y₁-Neuropeptide Y-Gi1/&β;1/&γ;2
30.30	Single	8FEG	PRD_002517	8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2
30.30	Single	8IY6	Endothelin-1	8IY6-ET_B-Endothelin-1
30.00	Single	5YQZ	Glucagon analogue	5YQZ-Glucagon-Glucagon analogue
30.00	Single	7C61	Ergotamine	7C61-5-HT_1B-Ergotamine
30.00	Single	7V6A	PubChem 9864275	7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
30.00	Single	7W40	Bombesin	7W40-BB₂-Bombesin-chim(NtGi1L-Gq)/&β;1/&γ;2
30.00	Single	8IA2	C5a anaphylatoxin	8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
30.00	Consensus	compl-peptide_on	Orthosteric Ligand	c5a1_on c3a_on
29.63	Single	5ZTY	AM10257	5ZTY-CB₂-AM10257
29.63	Single	6C1Q	PMX53	6C1Q-C5a₁-PMX53-NDT9513727
29.63	Single	7F9Z	GHRP-6	7F9Z-Ghrelin-GHRP-6-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
29.63	Single	7W2Z	Ghrelin	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
29.63	Single	7Y1F	Dynorphin	7Y1F-κ-Dynorphin-Gi1/&β;1/&γ;2
29.63	Single	8F7R	Endomorphin	8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2
29.63	Consensus	c3a_on	Orthosteric Ligand	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2 8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2 8I95-C3a_B-EP54-Go/&β;1/&γ;2
29.63	Consensus	cb2_off	Orthosteric Ligand	5ZTY-CB₂-AM10257
29.63	Consensus	gi_apelin	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
29.63	Consensus	gi_lipid	Orthosteric Ligand	gi_cannabinoid gi_prostanoid gi_ffa gi_lpl gi_leukotriene
29.63	Consensus	go_compl-peptide	Orthosteric Ligand	8I95-C3a_B-EP54-Go/&β;1/&γ;2 8IA2-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2 8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2 8J6D-C3a_B-EP141-Go/&β;1/&γ;2
29.63	Consensus	go_ghrelin	Orthosteric Ligand	7W2Z-Ghrelin-Ghrelin-Go/&β;1/&γ;2
29.63	Consensus	motilin_on	Orthosteric Ligand	8IBV-Motilin-Motilin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IBU-Motilin-Erythromycin A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
29.63	Consensus	ox2_on	Orthosteric Ligand	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
29.41	Single	5GLH	Endothelin-1	5GLH-ET_B-Endothelin-1
29.27	Single	8GY7	Corticotropin	8GY7-MC₂-Corticotropin-Ca-chim(NtGi1-Gs)/&β;1/&γ;2; MRAP1
29.17	Single	6LFM	Interleukin-8	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
29.17	Single	7T9N	PubChem 644078	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
29.17	Single	7YU3	ONO-0740556	7YU3-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
29.17	Single	7YU6	ONO-0740556	7YU6-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
29.17	Single	7YU7	ONO-0740556	7YU7-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
29.17	Single	8K8J	Fenofibrate	8K8J-CB₁-Fenofibrate-chim(Gs-CtGq)/&β;1/&γ;2
29.17	Consensus	cb2_on	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
29.03	Single	7LLY	Oxyntomodulin	7LLY-GLP-1-Oxyntomodulin-Gs/&β;1/&γ;2
29.03	Single	7YKD	Chemerin-9	7YKD-CML1-Chemerin-9-Gi1/&β;1/&γ;2
29.03	Consensus	gs_melanocortin	Orthosteric Ligand	7F4D-MC₁-Alpha-MSH-chim(NtGi1-Gs)/&β;1/&γ;2 7F4H-MC₁-Afamelanotide-chim(NtGi1-Gs)/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2 7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F4I-MC₁-SHU9119-chim(NtGi1-Gs)/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2
28.57	Single	4XT1	Fractalkine	4XT1-US28-Fractalkine
28.57	Single	7F54	Afamelanotide	7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
28.57	Single	7F8X	NN9056	7F8X-CCK_A-NN9056
28.57	Single	7SK6	CXCL12_LRHQ	7SK6-ACKR3-CXCL12_LRHQ
28.57	Single	7W0P	Elabela	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2
28.57	Single	8HBD	IRL1620	8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
28.57	Consensus	alpha1a_off	Orthosteric Ligand	7YMJ-Alpha1A-Tamsulosin 8HN1-Alpha1A-Toxin AdTx1
28.57	Consensus	apelin_on	Orthosteric Ligand	7W0P-Apelin-Elabela-Gi1/&β;1/&γ;2 7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
28.57	Consensus	fpr-alx_on	Orthosteric Ligand	fpr1-alx_on fpr2-alx_on
28.57	Consensus	gi_opioid	Orthosteric Ligand	8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 7U2K-μ-C6-guano-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2 8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 7SCG-μ-FH210-Gi1/&β;1/&γ;2 7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2 7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2 8DZP-κ-momSalB-Gi1/&β;1/&γ;2 8F7X-NOP-Nociceptin-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8FEG-κ-PRD_002517-Gi1/&β;1/&γ;2 7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
28.12	Single	4XT3	Fractalkine	4XT3-US28-Fractalkine
28.12	Single	7F8V	Gastrin-17	7F8V-CCK_B-Gastrin-17-Gi2/&β;1/&γ;2
28.12	Single	7RGP	Tirzepatide	7RGP-GLP-1-Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
28.12	Single	8JIS	Peptide-15	8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2
28.00	Single	4RWD	DIPP-NH2	4RWD-δ-DIPP-NH2-Na
28.00	Single	5TZR	-	5TZR-FFA1 (GPR40)-MK8666
28.00	Single	5XR8	AM841	5XR8-CB₁-AM841
28.00	Single	7M8W	15r-Methyl-Prostaglandin D2	7M8W-DP₂-15r-Methyl-Prostaglandin D2-Na
28.00	Single	7VIG	CBP-307	7VIG-S1P₁-CBP-307-Gi1/&β;1/&γ;2
28.00	Single	7XBD	Galanin	7XBD-GAL₂-Galanin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.00	Single	7XJL	Spexin	7XJL-GAL₂-Spexin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
28.00	Single	7Y67	C089 peptide	7Y67-C5a₁-C089 peptide-Gi1/&β;1/&γ;2
28.00	Single	7YU5	ONO-0740556	7YU5-LPA₁-ONO-0740556-Gi1/&β;1/&γ;2
28.00	Single	8GUS	HU-308	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2
28.00	Single	8I9A	EP54	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
28.00	Consensus	cck_on	Orthosteric Ligand	ccka_on cckb_on
28.00	Consensus	ccka_on	Orthosteric Ligand	7EZH-CCK_A-Cholecystokinin-8-Gi1/&β;1/&γ;2 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
28.00	Consensus	gs_compl-peptide	Orthosteric Ligand	8I9A-C3a_B-EP54-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
28.00	Consensus	nts1_on_allo	Orthosteric Ligand	8JPB-NTS₁-Neurotensin 8-13-PubChem 118610427; GDP; Mg-Gq; GRK2
27.78	Single	8U1U	CCL1	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
27.59	Single	7PIV	Setmelanotide	7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2
27.59	Single	7RKM	Fractalkine	7RKM-US28-Fractalkine-Gi1/&β;1/&γ;2
27.59	Single	7WJ5	Somatostatin-14	7WJ5-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
27.59	Single	8F7W	Dynorphin	8F7W-κ-Dynorphin-Gi1/&β;1/&γ;2
27.27	Single	7F53	Alpha-MSH	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2
27.27	Single	8FN0	Neurotensin/neuromedin N	8FN0-NTS₁-Neurotensin/neuromedin N-PubChem 118610427-chim(NtGi1-Go)/&β;1/&γ;2
27.27	Single	8GNG	Istradefylline	8GNG-A_2A-Istradefylline
27.27	Consensus	ccr8_on	Orthosteric Ligand	8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
27.27	Consensus	p2y_off	Orthosteric Ligand	p2y1_off p2y12_off
26.92	Single	4Z36	ONO-3080573	4Z36-LPA₁-ONO-3080573
26.92	Single	6C1R	PMX53	6C1R-C5a₁-PMX53-Avacopan; Na
26.92	Single	6KPG	AM841	6KPG-CB₁-AM841-Gi1/&β;1/&γ;2
26.92	Single	7EW2	Fingolimod	7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
26.92	Single	8HK2	C3a anaphylatoxin	8HK2-C3a_B-C3a anaphylatoxin-Gi1/&β;1/&γ;2
26.92	Single	8I9L	C3a anaphylatoxin	8I9L-C3a_B-C3a anaphylatoxin-Go/&β;1/&γ;2
26.92	Single	8IA8	E7 peptide	8IA8-C3a_B-E7 peptide-Gi1/&β;1/&γ;2
26.92	Consensus	cannabinoid_off	Orthosteric Ligand	cb1_off cb2_off
26.92	Consensus	cannabinoid_on	Orthosteric Ligand	cb1_on cb2_on
26.92	Consensus	cb1_on	Orthosteric Ligand	8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
26.92	Consensus	dp2_off	Orthosteric Ligand	6D27-DP₂-CAY10471 6D26-DP₂-Fevipiprant
26.92	Consensus	dp_off	Orthosteric Ligand	dp2_off
26.92	Consensus	gi_cannabinoid	Orthosteric Ligand	8GUS-CB₂-HU-308-Gi1/&β;1/&γ;2 8GUT-CB₂-LEI-102-Gi1/&β;1/&γ;2 8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2 8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2 6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2 6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2 6KPG-CB₁-AM841-Gi1/&β;1/&γ;2 6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2 8GHV-CB₁-PubChem 145964903-Gi1/&β;1/&γ;2
26.92	Consensus	nts1_on	Orthosteric Ligand	6OS9-NTS₁-JMV449-Gi1/&β;1/&γ;2
26.92	Consensus	nts_on	Orthosteric Ligand	nts1_on
26.67	Single	3OE0	CVX15	3OE0-CXCR4-CVX15
26.67	Single	6LW5	WKYMVm	6LW5-FPR2-ALX-WKYMVm
26.67	Single	7TD0	LPA	7TD0-LPA₁-LPA-Gi1/&β;1/&γ;2
26.67	Single	7TD2	LPA	7TD2-LPA₁-LPA-Gi1/&β;1/&γ;2
26.67	Single	7W55	Neuromedin-U-25	7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
26.67	Single	7XA3	CCL2	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
26.67	Single	7XAU	Octreotide	7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2
26.67	Single	7XNA	CYN154806	7XNA-SST2-CYN154806
26.67	Consensus	ccr2_on	Orthosteric Ligand	7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2
26.67	Consensus	gi_formylpeptide	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2 7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
26.67	Consensus	mc3_on	Orthosteric Ligand	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
26.67	Consensus	sst2_off	Orthosteric Ligand	7XNA-SST2-CYN154806
26.47	Single	6B3J	Exendin-P5	6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2
26.47	Single	6IGL	IRL1620	6IGL-ET_B-IRL1620
26.47	Single	8IY5	Endothelin-1	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2
26.09	Single	5K2B	ZM241385	5K2B-A_2A-ZM241385-Na
26.09	Single	5NLX	ZM241385	5NLX-A_2A-ZM241385-Na
26.09	Single	5UVI	ZM241385	5UVI-A_2A-ZM241385
26.09	Single	6MH8	ZM241385	6MH8-A_2A-ZM241385
26.09	Single	6PT0	WIN 55212-2	6PT0-CB₂-WIN 55212-2-Gi1/&β;1/&γ;2
26.09	Single	6ZA8	RTI-3a	6ZA8-NTS₁-RTI-3a
26.09	Single	7UTZ	PubChem 644078	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
26.09	Single	7XXH	2MeSADP	7XXH-P2Y₁-2MeSADP-chim(NtGi1-G11)/&β;1/&γ;2
26.09	Single	8GUR	PubChem 104895	8GUR-CB₂-PubChem 104895-Gi1/&β;1/&γ;2
26.09	Consensus	cxcr2_on	Orthosteric Ligand	6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
26.09	Consensus	ffa2_on	Orthosteric Ligand	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
26.09	Consensus	lh_on_allo	Other Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
25.93	Single	5TZY	MK8666; PubChem 127053597	5TZY-FFA1 (GPR40)-MK8666; PubChem 127053597
25.93	Single	6DDF	Damgo	6DDF-μ-Damgo-Gi1/&β;1/&γ;2
25.93	Single	7EZC	UKA	7EZC-A_2A-UKA
25.93	Single	7EZM	Cholecystokinin-8	7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2
25.93	Single	7WVV	fMLFII	7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2
25.93	Single	7X2D	Tavapadon	7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2
25.93	Single	7Y65	C5a peptide	7Y65-C5a₁-C5a peptide-Gi1/&β;1/&γ;2
25.93	Single	8GAG	YVF	8GAG-CB₁-YVF-Gi1/&β;1/&γ;2
25.93	Single	8HN1	Toxin AdTx1	8HN1-Alpha1A-Toxin AdTx1
25.93	Single	8IYS	TUG-891	8IYS-FFA4-TUG-891-GDP-chim(NtGi1L-Gq)/&β;1/&γ;2
25.93	Single	8WRZ	8D0	8WRZ-CB₁-8D0-Arrestin1
25.93	Consensus	gi_class-a	Orthosteric Ligand	gi_amine gi_lipid gi_melatonin gi_peptide gi_protein gi_nucleotide gi_hcar
25.93	Consensus	gs_cck	Orthosteric Ligand	7MBX-CCK_A-Cholecystokinin-8-Gs/&β;1/&γ;1 7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
25.93	Consensus	gs_orexin	Orthosteric Ligand	7L1U-OX₂-Orexin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
25.93	Consensus	orexin_on	Orthosteric Ligand	ox2_on
25.81	Single	7FIM	Tirzepatide	7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
25.81	Consensus	gi_somatostatin	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XMT-SST4-J-2156-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
25.81	Consensus	nmur2_on	Orthosteric Ligand	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7W55-NMUR2-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.71	Single	7DUQ	GLP-1	7DUQ-GLP-1-GLP-1-PubChem 156022738-Gs/&β;1/&γ;2
25.00	Single	3EML	ZM241385	3EML-A_2A-ZM241385
25.00	Single	4UG2	CGS21680	4UG2-A_2A-CGS21680
25.00	Single	5K2A	ZM241385	5K2A-A_2A-ZM241385-Na
25.00	Single	5T04	Neurotensin	5T04-NTS₁-Neurotensin
25.00	Single	5VRA	ZM241385	5VRA-A_2A-ZM241385-Na
25.00	Single	6KNM	JN241-9	6KNM-Apelin-JN241-9
25.00	Single	6LPJ	ZM241385	6LPJ-A_2A-ZM241385-Na
25.00	Single	6LPK	ZM241385	6LPK-A_2A-ZM241385-Na
25.00	Single	6S0L	ZM241385	6S0L-A_2A-ZM241385
25.00	Single	6X18	GLP-1	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2
25.00	Single	6X1A	Danuglipron	6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2
25.00	Single	7F8W	Gastrin-17	7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2
25.00	Single	7FIH	Org43553	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Single	7LCK	Danuglipron	7LCK-GLP-1-Danuglipron
25.00	Single	7NA8	PubChem 178024	7NA8-Ghrelin-PubChem 178024-Gi1/&β;1/&γ;2
25.00	Single	7S15	PubChem 134611223	7S15-GLP-1-PubChem 134611223
25.00	Single	7S8L	Cortistatin-14	7S8L-MRGPRX2-Cortistatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
25.00	Single	7SK8	CXCL12	7SK8-ACKR3-CXCL12-CCX662
25.00	Single	7VBH	Peptide-20	7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2
25.00	Single	7VIE	S1P	7VIE-S1P₁-S1P-Gi1/&β;1/&γ;2
25.00	Single	7X8S	WB4-24	7X8S-GLP-1-WB4-24-Gs/&β;1/&γ;2
25.00	Single	7YAE	Octreotide	7YAE-SST2-Octreotide-Gi1/&β;1/&γ;2
25.00	Single	8EJC	TAK-875	8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
25.00	Single	8H4I	Doconexent	8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
25.00	Single	8HCQ	Endothelin-1	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Single	8IA7	Cholecystokinin-8	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
25.00	Single	8X17	Namodenoson	8X17-A3A-Namodenoson-Gi1/&β;1/&γ;2
25.00	Consensus	alpha_off	Orthosteric Ligand	alpha1_off alpha2_off
25.00	Consensus	cck_off	Orthosteric Ligand	ccka_off
25.00	Consensus	ccka_off	Orthosteric Ligand	7F8Y-CCK_A-Devazepide 7F8U-CCK_A-Lintitript
25.00	Consensus	chemokine_on	Orthosteric Ligand	cxcr_on cx3cr_on
25.00	Consensus	eta_on	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
25.00	Consensus	ffa_on	Orthosteric Ligand	ffa4_on ffa1_on ffa2_on ffa3_on
25.00	Consensus	fpr2-alx_on	Orthosteric Ligand	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2 7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2 7WVV-FPR2-ALX-fMLFII-Gi2/&β;1/&γ;2 7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2 7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2 7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2 6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
25.00	Consensus	gq_cck	Orthosteric Ligand	8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 7EZM-CCK_A-Cholecystokinin-8-chim(NtGsL-Gq)/&β;1/&γ;2 7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
25.00	Consensus	gq_class-a	Orthosteric Ligand	gq_amine gq_peptide
25.00	Consensus	lipid_off	Orthosteric Ligand	cannabinoid_off leuko_off lpl_off paf_off prostanoid_off
25.00	Consensus	lipid_on	Orthosteric Ligand	cannabinoid_on ffa_on gpr119_on leuko_on lpl_on prostanoid_on
25.00	Consensus	mc4_on	Orthosteric Ligand	7F53-MC₄-Alpha-MSH-Gs/&β;1/&γ;2 7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2 7PIV-MC₄-Setmelanotide-Gs/&β;1/&γ;2 7F58-MC₄-THIQ-Gs/&β;1/&γ;2 7F54-MC₄-Afamelanotide-Gs/&β;1/&γ;2
25.00	Consensus	nucleotide_off	Orthosteric Ligand	adenosine_off p2y_off
24.24	Single	5UIW	5P7-CCL5	5UIW-CCR5-5P7-CCL5
24.24	Single	6NBF	Long-acting PTH analog	6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
24.24	Single	7W57	Neuromedin-S	7W57-NMUR2-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
24.24	Single	8HAO	PTH	8HAO-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
24.24	Consensus	ccr5_off	Orthosteric Ligand	5UIW-CCR5-5P7-CCL5
24.24	Consensus	ccr5_on	Orthosteric Ligand	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
24.24	Consensus	npy4_on	Orthosteric Ligand	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
24.14	Single	7TD4	Siponimod	7TD4-S1P₁-Siponimod-Gi1/&β;1/&γ;2
24.14	Single	7W53	Neuromedin-U-25	7W53-NMUR1-Neuromedin-U-25-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
24.14	Single	7WKD	TRH	7WKD-TRH-TRH-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
24.14	Single	8JZZ	C5a-desArg	8JZZ-C5a₁-C5a-desArg-Go/&β;1/&γ;2
24.14	Single	8U4O	CXCL12	8U4O-CXCR4-CXCL12-Cholesterol-Gi1/&β;1/&γ;2
24.14	Consensus	nmur1_on	Orthosteric Ligand	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
24.14	Consensus	sst2_on	Orthosteric Ligand	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2 7XAU-SST2-Octreotide-Gi1/&β;1/&γ;2 7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
24.14	Consensus	sst_on	Orthosteric Ligand	sst2_on sst4_on
24.00	Single	4PHU	Fasiglifam	4PHU-FFA1 (GPR40)-Fasiglifam
24.00	Single	5IUA	Q27456348	5IUA-A_2A-Q27456348-Na
24.00	Single	5NM2	ZM241385	5NM2-A_2A-ZM241385-Na
24.00	Single	6KPC	PubChem 145915889	6KPC-CB₂-PubChem 145915889
24.00	Single	6LPL	ZM241385	6LPL-A_2A-ZM241385-Na
24.00	Single	6N4B	MDMB-Fubinaca	6N4B-CB₁-MDMB-Fubinaca-Gi1/&β;1/&γ;2
24.00	Single	6RZ5	Zafirlukast	6RZ5-CysLT₁-Zafirlukast-Na
24.00	Single	6S0Q	ZM241385	6S0Q-A_2A-ZM241385
24.00	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
24.00	Single	6WQA	ZM241385	6WQA-A_2A-ZM241385-Na
24.00	Single	7CKX	A77636	7CKX-D₁-A77636-Gs/&β;1/&γ;2
24.00	Single	7EO2	FTY720-P	7EO2-S1P₁-FTY720-P-Gi1/&β;1/&γ;2
24.00	Single	7RM5	ZM241385	7RM5-A_2A-ZM241385-Na
24.00	Single	7TD3	S1P	7TD3-S1P₁-S1P-Gi1/&β;1/&γ;2
24.00	Single	7VUH	JNJ-63533054	7VUH-GPR139-JNJ-63533054-chim(Gs-CtGq)/&β;1/&γ;2
24.00	Single	7YXA	ONO-5430608	7YXA-S1P₅-ONO-5430608
24.00	Single	8DZQ	momSalB	8DZQ-κ-momSalB-Go/&β;1/&γ;2
24.00	Single	8FYN	ZM241385	8FYN-A_2A-ZM241385-Na
24.00	Consensus	go_opioid	Orthosteric Ligand	8DZQ-κ-momSalB-Go/&β;1/&γ;2
23.81	Single	4XNW	MRS2500	4XNW-P2Y₁-MRS2500
23.81	Single	6ME5	Agomelatine	6ME5-MT₁-Agomelatine
23.81	Single	6OIK	LY2119620	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
23.81	Single	7WC5	Psilocin	7WC5-5-HT_2A-Psilocin
23.81	Single	8J24	Acetic acid	8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2
23.81	Consensus	p2y1_off	Orthosteric Ligand	4XNW-P2Y₁-MRS2500
23.68	Consensus	gs_glucagon	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 6WZG-Secretin-Secretin-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2 7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2 7DTY-GIP-GIP-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
23.53	Single	7S1M	Ex4-D-Ala	7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2
23.53	Single	7WVY	Amyloid-Beta42	7WVY-FPR2-ALX-Amyloid-Beta42-Gi2/&β;1/&γ;2
23.53	Single	8FU6	Glucagon derivative ZP3780	8FU6-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
23.53	Consensus	endothelin_on	Orthosteric Ligand	etb_on eta_on
23.53	Consensus	etb_on	Orthosteric Ligand	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
23.33	Single	3QAK	UK-432097	3QAK-A_2A-UK-432097
23.33	Single	7C6A	(Sar1,Ile8)-Angiotensin II	7C6A-AT₂-(Sar1,Ile8)-Angiotensin II
23.33	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
23.33	Single	7F1Q	MIP-1a	7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2
23.33	Single	7PIU	Setmelanotide	7PIU-MC₄-Setmelanotide-Gs/&β;1/&γ;2
23.33	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
23.33	Single	7W56	Neuromedin-S	7W56-NMUR1-Neuromedin-S-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
23.33	Single	7XMS	Somatostatin-14	7XMS-SST4-Somatostatin-14-Gi1/&β;1/&γ;2
23.33	Single	8DWG	Proenkephalin-A	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
23.33	Single	8F7S	Deltorphin	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
23.33	Single	8IOC	Gamma-MSH	8IOC-MC₃-Gamma-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
23.33	Consensus	cx3cr_on	Orthosteric Ligand	cx3cr1_on
23.33	Consensus	sst_off	Orthosteric Ligand	sst2_off
23.08	Single	3SN6	BI167107	3SN6-β₂-BI167107-Gs/&β;1/&γ;2
23.08	Single	4RWA	DIPP-NH2	4RWA-δ-DIPP-NH2
23.08	Single	5V56	TC114	5V56-SMO-TC114
23.08	Single	6OS1	TRV026	6OS1-AT₁-TRV026
23.08	Single	6W2X	PubChem 23727970	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
23.08	Single	7B6W	Cyclazosin	7B6W-α_1b-Cyclazosin
23.08	Single	7CKY	PW0464	7CKY-D₁-PW0464-Gs/&β;1/&γ;2
23.08	Single	7F1T	MIP-1a	7F1T-CCR5-MIP-1a
23.08	Single	7JV5	SKF81297	7JV5-D₁-SKF81297-Gs/&β;1/&γ;2
23.08	Single	7JVP	SKF83959	7JVP-D₁-SKF83959-Gs/&β;1/&γ;2
23.08	Single	7PX4	PSB-2113	7PX4-A_2A-PSB-2113
23.08	Single	7SK7	CXCL12	7SK7-ACKR3-CXCL12-CCX662
23.08	Single	7TD1	LPA	7TD1-LPA₁-LPA-Gi1/&β;1/&γ;2
23.08	Single	7XOW	Gastrin	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2
23.08	Single	7XOX	Cholecystokinin-8	7XOX-CCK_B-Cholecystokinin-8-Gq/&β;1/&γ;2
23.08	Single	8DZP	momSalB	8DZP-κ-momSalB-Gi1/&β;1/&γ;2
23.08	Single	8E0G	BU72	8E0G-μ-BU72
23.08	Single	8EFL	SR17018	8EFL-μ-SR17018-Gi1/&β;1/&γ;2
23.08	Single	8HPT	C5a anaphylatoxin C-terminal peptide	8HPT-C5a₁-C5a anaphylatoxin C-terminal peptide-Go/&β;1/&γ;2
23.08	Single	8HQC	C5a anaphylatoxin	8HQC-C5a₁-C5a anaphylatoxin-Go/&β;1/&γ;2
23.08	Single	8ID3	9-Hydroxystearic acid	8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2
23.08	Single	8ID6	Oleic acid	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2
23.08	Consensus	alpha1b_off	Orthosteric Ligand	7B6W-α_1b-Cyclazosin
23.08	Consensus	arrestin2	Orthosteric Ligand	6TKO-β₁-Arformoterol-Arrestin2 6PWC-NTS₁-Neurotensin-Arrestin2 7R0C-V₂-Acyclovir triphosphate-Arrestin2
23.08	Consensus	class-a_off	Orthosteric Ligand	sensory_off amine_off lipid_off nucleotide_off peptide_off protein_off hcar_off
23.08	Consensus	cyslt1_off_ortoallo	Orthosteric Ligand	6RZ5-CysLT₁-Zafirlukast-Na 6RZ4-CysLT₁-Pranlukast-Na
23.08	Consensus	ffa4_on	Orthosteric Ligand	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8H4I-FFA4-Doconexent-chim(NtGi1-Gs)/&β;1/&γ;2
23.08	Consensus	gi_ffa	Orthosteric Ligand	8ID6-FFA4 (GPR120)-Oleic acid-Gi1/&β;1/&γ;2 8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2 8ID3-FFA4 (GPR120)-9-Hydroxystearic acid-Gi1/&β;1/&γ;2 8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2 8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2 8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2 8J24-FFA2-Acetic acid-Gi1/&β;1/&γ;2 8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
23.08	Consensus	gs_ffa	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2 8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
23.08	Consensus	pth_on	Orthosteric Ligand	pth1_on pth2_on
23.08	Consensus	s1p3_on	Orthosteric Ligand	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2 7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2 7EW2-S1P₃-Fingolimod-Gi1/&β;1/&γ;2
22.86	Single	6NBH	Long-acting PTH analog	6NBH-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
22.86	Single	7KI1	Taspoglutide	7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2
22.86	Consensus	gi_chemokine	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2 7XA3-CCR2-CCL2-Gi1/&β;1/&γ;2 7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1 7F1Q-CCR5-MIP-1a-Gi1/&β;1/&γ;2 7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2 8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2 6LFM-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2 8U1U-CCR8-CCL1-Gi1/&β;1/&γ;2
22.86	Consensus	gs_endothelin	Orthosteric Ligand	8HCQ-ET_A-Endothelin-1-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
22.73	Single	6TP4	ACT-462206	6TP4-OX₁-ACT-462206
22.73	Single	6U1N	LY2119620	6U1N-M₂-LY2119620-Arrestin2
22.73	Single	7VDH	C48/80	7VDH-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
22.73	Single	7VUI	JNJ-63533054	7VUI-GPR139-JNJ-63533054-GTP-chim(Gs-CtGq)/&β;1/&γ;2
22.73	Consensus	go_chemokine	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
22.73	Consensus	go_protein	Orthosteric Ligand	go_chemokine
22.58	Single	5WF5	UK-432097	5WF5-A_2A-UK-432097
22.58	Single	7O7F	(6P4)CCL5	7O7F-CCR5-(6P4)CCL5-Gi1/&β;1/&γ;1
22.58	Single	8XZH	MM07	8XZH-Apelin-MM07-Gi1/&β;1/&γ;2
22.58	Consensus	angiotensin_on	Orthosteric Ligand	at1_on
22.58	Consensus	at1_on	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
22.58	Consensus	ccr_off	Orthosteric Ligand	ccr5_off ccr8_off
22.58	Consensus	cx3cr1_on	Orthosteric Ligand	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
22.58	Consensus	gs_class-a	Orthosteric Ligand	gs_amine gs_nucleotide gs_lipid gs_peptide gs_protein gs_steroid
22.22	Single	5VAI	GLP-1	5VAI-GLP-1-GLP-1-Gs/&β;1/&γ;2
22.22	Single	6HLP	Netupitant	6HLP-NK₁-Netupitant
22.22	Single	6OS0	Angiotensinogen	6OS0-AT₁-Angiotensinogen
22.22	Single	6OS2	TRV026	6OS2-AT₁-TRV026
22.22	Single	6VMS	Bromoergocryptine	6VMS-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
22.22	Single	7DH5	Mirabegron	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2
22.22	Single	7EVY	Siponimod	7EVY-S1P₁-Siponimod-Gi1/&β;1/&γ;2
22.22	Single	7F55	Bremelanotide	7F55-MC₄-Bremelanotide-Gs/&β;1/&γ;2
22.22	Single	7SUS	PubChem 122701908	7SUS-Apelin-PubChem 122701908
22.22	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
22.22	Single	7W0N	Elabela	7W0N-Apelin-Elabela-Gi1/&β;1/&γ;2
22.22	Single	7X1T	Taltirelin	7X1T-TRH-Taltirelin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
22.22	Single	7XW5	ML109	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
22.22	Single	7XW6	ML109	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
22.22	Single	8DWC	Proenkephalin-A	8DWC-MRGPRX1-Proenkephalin-A-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
22.22	Single	8I95	EP54	8I95-C3a_B-EP54-Go/&β;1/&γ;2
22.22	Single	8JGF	BAM8-22	8JGF-MRGPRX1-BAM8-22-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
22.22	Single	8JJL	Olodaterol	8JJL-β₂-Olodaterol
22.22	Single	8T3Q	DHA	8T3Q-FFA4-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
22.22	Consensus	chemokine_off	Orthosteric Ligand	cxcr_off
22.22	Consensus	cxcr4_off	Orthosteric Ligand	4RWS-CXCR4-vMIP-II
22.22	Consensus	cxcr_off	Orthosteric Ligand	cxcr4_off
22.22	Consensus	gpr119_on	Orthosteric Ligand	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2 7WCN-GPR119-AR231453-Gs/&β;1/&γ;2 7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2 7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
22.22	Consensus	m4_on	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
22.22	Consensus	mop_on	Orthosteric Ligand	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2 8EFQ-μ-Damgo-Gi1/&β;1/&γ;2 8F7R-μ-Endomorphin-Gi1/&β;1/&γ;2 8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2 8EF6-μ-Morphine-Gi1/&β;1/&γ;2 8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2 8EFO-μ-PZM21-Gi1/&β;1/&γ;2 8EFL-μ-SR17018-Gi1/&β;1/&γ;2
22.22	Consensus	peptide_off	Orthosteric Ligand	opioid_off angiotensin_off bombesin_off cck_off endothelin_off ghrelin_off npy_off nts_off orexin_off vasopressin-ot_off tachykinin_off sst_off
22.22	Consensus	s1p_on	Orthosteric Ligand	s1p3_on s1p5_on s1p1_on s1p2_on
22.22	Consensus	tsh_on_allo	Other Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
21.95	Single	7F16	TIP39	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
21.95	Consensus	gs_pth	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7F16-PTH2-TIP39-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
21.88	Single	5WB2	CX3CL1.35	5WB2-US28-CX3CL1.35
21.88	Single	6JOD	Angiotensin II	6JOD-AT₂-Angiotensin II
21.88	Single	7F6G	SAR1-AngII	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
21.88	Single	8H4K	GW9508	8H4K-FFA4-GW9508-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
21.88	Single	8XZJ	WN353	8XZJ-Apelin-WN353-Gi1/&β;1/&γ;2
21.88	Consensus	bk2_on	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
21.88	Consensus	go_class-b	Orthosteric Ligand	go_class-b1 go_class-b2
21.88	Consensus	gq_angiotensin	Orthosteric Ligand	7F6G-AT₁-SAR1-AngII-Gq/&β;1/&γ;2
21.74	Single	2X72	All-trans-retinal	2X72-Rhodopsin-All-trans-retinal-Gt(CT)
21.74	Single	3PWH	ZM241385	3PWH-A_2A-ZM241385
21.74	Single	3VG9	ZM241385	3VG9-A_2A-ZM241385-Antibody
21.74	Single	3VGA	ZM241385	3VGA-A_2A-ZM241385-Antibody
21.74	Single	5K2D	ZM241385	5K2D-A_2A-ZM241385
21.74	Single	5OLO	Tozadenant	5OLO-A_2A-Tozadenant-Na
21.74	Single	6JZH	ZM241385	6JZH-A_2A-ZM241385-Na
21.74	Single	6LFO	Interleukin-8	6LFO-CXCR2-Interleukin-8-Gi1/&β;1/&γ;2
21.74	Single	6NWE	Octyl Beta-D-Glucopyranoside	6NWE-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
21.74	Single	6PS7	ZM241385	6PS7-A_2A-ZM241385-Na
21.74	Single	6TQ6	PubChem 145714283	6TQ6-OX₁-PubChem 145714283
21.74	Single	6WWZ	CCL20	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
21.74	Single	7F8U	Lintitript	7F8U-CCK_A-Lintitript
21.74	Single	7F8Y	Devazepide	7F8Y-CCK_A-Devazepide
21.74	Single	7LCJ	Danuglipron	7LCJ-GLP-1-Danuglipron
21.74	Single	7VIH	CBP-307	7VIH-S1P₁-CBP-307-Gi1/&β;1/&γ;2
21.74	Single	7W0M	PubChem 122701908	7W0M-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
21.74	Single	7WF7	S1P	7WF7-S1P₁-S1P-Gi1/&β;1/&γ;2
21.74	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
21.74	Single	8T3S	Butyric acid	8T3S-FFA2-Butyric acid-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
21.74	Consensus	ccr6_on	Orthosteric Ligand	6WWZ-CCR6-CCL20-Go/&β;1/&γ;2
21.74	Consensus	m2_on_allo	Other Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
21.62	Single	6WPW	Glucagon derivative ZP3780	6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2
21.62	Single	8FLU	Long-acting PTH	8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2
21.62	Consensus	gi_endothelin	Orthosteric Ligand	8IY5-ET_B-Endothelin-1-Gi1/&β;1/&γ;2 8HBD-ET_B-IRL1620-Gi1/&β;1/&γ;2
21.62	Consensus	glp_on	Orthosteric Ligand	glp1_on glp2_on
21.43	Single	4PXZ	2MeSADP	4PXZ-P2Y₁₂-2MeSADP
21.43	Single	4RWS	vMIP-II	4RWS-CXCR4-vMIP-II
21.43	Single	5TUD	Ergotamine	5TUD-5-HT_2B-Ergotamine
21.43	Single	6BQG	Ergotamine	6BQG-5-HT_2C-Ergotamine
21.43	Single	6IBL	Arformoterol	6IBL-β₁-Arformoterol
21.43	Single	7EVZ	Cenerimod	7EVZ-S1P₁-Cenerimod-Gi1/&β;1/&γ;2
21.43	Single	7EW0	Ozanimod	7EW0-S1P₁-Ozanimod-Gi1/&β;1/&γ;2
21.43	Single	7MBY	Cholecystokinin-8	7MBY-CCK_A-Cholecystokinin-8-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
21.43	Single	7X8R	BOC5	7X8R-GLP-1-BOC5-Gs/&β;1/&γ;2
21.43	Single	7XJI	Solabegron	7XJI-β₃-Solabegron-Gs/&β;1/&γ;2
21.43	Consensus	c5a1_off_ortoallo	Orthosteric Ligand	6C1Q-C5a₁-PMX53-NDT9513727 6C1R-C5a₁-PMX53-Avacopan; Na
21.43	Consensus	cckb_on	Orthosteric Ligand	7XOW-CCK_B-Gastrin-Gq/&β;1/&γ;2 7F8W-CCK_B-Gastrin-17-chim(NtGsL-Gq)/&β;1/&γ;2 8IA7-CCK_B-Cholecystokinin-8-chim(NtGi1L-Gq)/&β;1/&γ;2
21.21	Single	7F6H	Bradykinin	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2
21.21	Single	7F6I	Kallidin	7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
21.21	Single	7KH0	Acyclovir triphosphate	7KH0-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
21.21	Single	7VL9	CCL15(26-92)	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
21.21	Single	7X9C	Pancreatic Hormone	7X9C-Y₄-Pancreatic Hormone-Gi1/&β;1/&γ;2
21.21	Single	7XAT	Somatostatin-14	7XAT-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
21.21	Single	8HCX	Endothelin-1	8HCX-ET_B-Endothelin-1-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.83	Single	3REY	PubChem 5697	3REY-A_2A-PubChem 5697
20.83	Single	3V2Y	PubChem 51892645	3V2Y-S1P₁-PubChem 51892645
20.83	Single	5IU4	ZM241385	5IU4-A_2A-ZM241385-Na
20.83	Single	5IU7	Q27456346	5IU7-A_2A-Q27456346-Na
20.83	Single	5IUB	Q27456344	5IUB-A_2A-Q27456344-Na
20.83	Single	5JTB	ZM241385	5JTB-A_2A-ZM241385
20.83	Single	5K2C	ZM241385	5K2C-A_2A-ZM241385-Na
20.83	Single	5NM4	ZM241385	5NM4-A_2A-ZM241385-Na
20.83	Single	5TE3	Octyl Beta-D-Glucopyranoside	5TE3-Rhodopsin-Octyl Beta-D-Glucopyranoside
20.83	Single	6DS0	Ly266097	6DS0-5-HT_2B-Ly266097
20.83	Single	6ME3	2-Phenylmelatonin	6ME3-MT₁-2-Phenylmelatonin
20.83	Single	6ME4	2-Iodomelatonin	6ME4-MT₁-2-Iodomelatonin
20.83	Single	6TP3	Nemorexant	6TP3-OX₁-Nemorexant
20.83	Single	6TPN	HTL6641	6TPN-OX₂-HTL6641
20.83	Single	6ZDR	HMS1413f12	6ZDR-A_2A-HMS1413f12-Na
20.83	Single	7ARO	LUF5833	7ARO-A_2A-LUF5833-Na
20.83	Single	7JOZ	VFP	7JOZ-D₁-VFP-Gs/&β;1/&γ;2
20.83	Single	7S8P	MS47134	7S8P-MRGPRX4-MS47134-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.83	Single	7T32	ZM241385	7T32-A_2A-ZM241385
20.83	Single	7TRQ	VU0467154	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
20.83	Single	7VUG	JNJ-63533054	7VUG-GPR139-JNJ-63533054-Gi1/&β;1/&γ;2
20.83	Single	7XOV	SR146131	7XOV-CCK_A-SR146131-Gs/&β;1/&γ;2
20.83	Single	8DWG	ML382	8DWG-MRGPRX1-Proenkephalin-A-ML382-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.83	Single	8GUQ	Olorinab	8GUQ-CB₂-Olorinab-Gi1/&β;1/&γ;2
20.83	Single	8HQN	9(S)-HODE	8HQN-GPR132-9(S)-HODE-Gi1/&β;1/&γ;2
20.83	Single	8T3V	DHA	8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.83	Consensus	cxcr_on	Orthosteric Ligand	cxcr1_on cxcr2_on
20.83	Consensus	gnrh_off	Orthosteric Ligand	gnrh1_off
20.83	Consensus	ox2_off	Orthosteric Ligand	6TPN-OX₂-HTL6641 7XRR-OX₂-Lemborexant
20.83	Consensus	s1p1_off	Orthosteric Ligand	3V2Y-S1P₁-PubChem 51892645
20.83	Consensus	s1p_off	Orthosteric Ligand	s1p1_off
20.69	Single	5WF6	UK-432097	5WF6-A_2A-UK-432097
20.69	Single	6OMM	WKYMVX	6OMM-FPR2-ALX-WKYMVX-Gi1/&β;1/&γ;2
20.69	Single	7F2O	Bradykinin	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
20.69	Single	7RKN	Fractalkine	7RKN-US28-Fractalkine-Gi1/&β;1/&γ;2
20.69	Single	7X1U	TRH	7X1U-TRH-TRH-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.69	Single	7YJ4	INSL5	7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2
20.69	Single	8INR	Alpha-MSH	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
20.69	Consensus	dop_on	Orthosteric Ligand	8F7S-δ-Deltorphin-Gi1/&β;1/&γ;2
20.59	Single	6NBI	Long-acting PTH analog	6NBI-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2
20.59	Single	7KI0	Semaglutide	7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2
20.59	Single	7SK3	CXCL12	7SK3-ACKR3-CXCL12
20.59	Single	7SK4	CXCL12_LRHQ	7SK4-ACKR3-CXCL12_LRHQ
20.59	Single	8FLR	PTHrP(1-36)	8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
20.59	Consensus	bradykinin_on	Orthosteric Ligand	bk2_on bk1_on
20.51	Single	7Y36	Teriparatide	7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2
20.51	Single	8FLQ	PTH	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2
20.00	Single	2Y02	Carmoterol	2Y02-β₁-Carmoterol
20.00	Single	4EIY	ZM241385	4EIY-A_2A-ZM241385-Na
20.00	Single	4IAR	Ergotamine	4IAR-5-HT_1B-Ergotamine
20.00	Single	4J4Q	Octyl Beta-D-Glucopyranoside	4J4Q-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
20.00	Single	4QIM	PubChem 24905375	4QIM-SMO-PubChem 24905375
20.00	Single	5IU8	Q27456347	5IU8-A_2A-Q27456347-Na
20.00	Single	5NX2	GLP-1 (Truncated)	5NX2-GLP-1-GLP-1 (Truncated)
20.00	Single	5OLG	ZM241385	5OLG-A_2A-ZM241385-Na
20.00	Single	5TGZ	AM6538	5TGZ-CB₁-AM6538
20.00	Single	5UIG	J3.651.884G	5UIG-A_2A-J3.651.884G
20.00	Single	5VBL	Apelin Mimetic Peptide Agonist	5VBL-Apelin-Apelin Mimetic Peptide Agonist
20.00	Single	6D27	CAY10471	6D27-DP₂-CAY10471
20.00	Single	6DRX	Lisuride	6DRX-5-HT_2B-Lisuride
20.00	Single	6KPF	PubChem 145915889	6KPF-CB₂-PubChem 145915889-Gi1/&β;1/&γ;2
20.00	Single	6PS8	2-Phenylmelatonin	6PS8-MT₁-2-Phenylmelatonin
20.00	Single	6RZ8	ONO-2080365	6RZ8-CysLT₂-ONO-2080365
20.00	Single	6VCB	GLP-1	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
20.00	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
20.00	Single	6X19	CHU-128	6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2
20.00	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
20.00	Single	7CRH	SKF83959	7CRH-D₁-SKF83959-Gs/&β;1/&γ;2
20.00	Single	7LJC	PubChem 86764103	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2
20.00	Single	7PYR	PSB-2115	7PYR-A_2A-PSB-2115
20.00	Single	7SCG	FH210	7SCG-μ-FH210-Gi1/&β;1/&γ;2
20.00	Single	7SQO	TAK-925	7SQO-OX₂-TAK-925-Gi1/&β;1/&γ;2
20.00	Single	7V68	PubChem 57664406	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
20.00	Single	7VGZ	Remalteon	7VGZ-MT₁-Remalteon-Gi1/&β;1/&γ;2
20.00	Single	7VIF	(S)-FTY720-P	7VIF-S1P₁-(S)-FTY720-P-Gi1/&β;1/&γ;2
20.00	Single	7VLA	CCL15(27-92)	7VLA-CCR1-CCL15(27-92)-Gi1/&β;1/&γ;2
20.00	Single	7VVJ	PTHrP(1-36)	7VVJ-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2
20.00	Single	7WC4	Serotonin	7WC4-5-HT_2A-Serotonin
20.00	Single	7WIC	Somatostatin-14	7WIC-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
20.00	Single	7WVW	fMYFINILTL	7WVW-FPR2-ALX-fMYFINILTL-Gi2/&β;1/&γ;2
20.00	Single	8EFQ	Damgo	8EFQ-μ-Damgo-Gi1/&β;1/&γ;2
20.00	Single	8EJK	TAK-875	8EJK-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
20.00	Single	8G59	TUG-891	8G59-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
20.00	Single	8ID4	Linoleic acid	8ID4-FFA4 (GPR120)-Linoleic acid-Gi1/&β;1/&γ;2
20.00	Single	8JGG	BAM8-22	8JGG-MRGPRX1-BAM8-22-Gi1/&β;1/&γ;2
20.00	Single	8XBH	S3E-LysoPS	8XBH-GPR34-S3E-LysoPS-Gi1/&β;1/&γ;2
20.00	Consensus	a2_off	Orthosteric Ligand	a2a_off
20.00	Consensus	a2a_off	Orthosteric Ligand	8C9W-A_2A-Etrumadenant 3UZA-A_2A-GTPL9236 8GNG-A_2A-Istradefylline 5UIG-A_2A-J3.651.884G 8CU6-A_2A-LJ-4517 7PX4-A_2A-PSB-2113 7PYR-A_2A-PSB-2115 8DU3-A_2A-PubChem 105526064 8JWY-A_2A-PubChem 168451710 5K2D-A_2A-ZM241385
20.00	Consensus	ccr_on	Orthosteric Ligand	ccr5_on ccr6_on ccr1_on ccr2_on ccr8_on
20.00	Consensus	ffa1_on	Orthosteric Ligand	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8EJC-FFA1 (GPR40)-TAK-875-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2 8T3V-FFA1-DHA-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
20.00	Consensus	fsh_on_allo	Other Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
20.00	Consensus	gi_hca	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
20.00	Consensus	gi_hcar	Orthosteric Ligand	gi_hca
20.00	Consensus	gi_protein	Orthosteric Ligand	gi_chemokine gi_chemerin
20.00	Consensus	gi_relaxin	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
20.00	Consensus	gs_class-b	Orthosteric Ligand	gs_class-b1 gs_class-b2
20.00	Consensus	hca2_on	Orthosteric Ligand	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2 8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2 8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2 8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2 8JHY-HCA₂-Compound 9n-Gi1/&β;1/&γ;2 8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2 8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2 8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2 8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2 8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
20.00	Consensus	mop_off	Orthosteric Ligand	7UL4-μ-Alvimopan 4DKL-μ-Beta-funaltrexamine 8QOT-μ-Nanobody E
20.00	Consensus	protein_off	Orthosteric Ligand	ccr_off chemokine_off gnrh_off
19.44	Single	6LML	Glucagon	6LML-Glucagon-Glucagon
19.44	Single	7D68	GLP-2	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
19.44	Single	8FLT	M-PTH(1-14)	8FLT-PTH1-M-PTH(1-14)-Gs/&β;1/&γ;2
19.44	Single	8HAF	PTHrP(1-36)	8HAF-PTH1-PTHrP(1-36)-chim(NtGi1-Gs)/&β;1/&γ;2
19.44	Consensus	gq_bradykinin	Orthosteric Ligand	7F6H-BK₂-Bradykinin-Gq/&β;1/&γ;2 7F6I-BK₂-Kallidin-Gq/&β;1/&γ;2
19.35	Single	4IB4	Ergotamine	4IB4-5-HT_2B-Ergotamine
19.35	Single	6DO1	Angiotensin-Like peptide S1I8	6DO1-AT₁-Angiotensin-Like peptide S1I8
19.35	Single	6HLO	Aprepitant	6HLO-NK₁-Aprepitant
19.35	Single	7E14	Orforglipron	7E14-GLP-1-Orforglipron-PubChem 156022738-Gs/&β;1/&γ;2
19.35	Single	7SK5	CXCL12	7SK5-ACKR3-CXCL12
19.35	Single	7VBI	Non-Acylated Tirzepatide	7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2
19.35	Single	7XBX	CX3CL1	7XBX-CX3CR1-CX3CL1-Gi1/&β;1/&γ;2
19.35	Single	8F7Q	Beta-endorphin	8F7Q-μ-Beta-endorphin-Gi1/&β;1/&γ;2
19.35	Single	8SG1	Chemerin-9	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
19.35	Consensus	vasopressin-ot_on	Orthosteric Ligand	ot_on v2_on
19.23	Single	4JKV	Taladegib (LY2940680)	4JKV-SMO-Taladegib (LY2940680)
19.23	Single	5C1M	BU72	5C1M-μ-BU72
19.23	Single	5N2R	PubChem 92460631; psb36	5N2R-A_2A-PubChem 92460631; psb36-Na
19.23	Single	5N2S	PSB36	5N2S-A₁-PSB36
19.23	Single	5ZBQ	UR-MK-299	5ZBQ-Y₁-UR-MK-299
19.23	Single	6D26	Fevipiprant	6D26-DP₂-Fevipiprant
19.23	Single	6DDE	Damgo	6DDE-μ-Damgo-Gi1/&β;1/&γ;2
19.23	Single	6ME7	2-Phenylmelatonin	6ME7-MT₂-2-Phenylmelatonin
19.23	Single	6TP6	Filorexant	6TP6-OX₁-Filorexant
19.23	Single	6XBK	Cholesterol	6XBK-SMO-Cholesterol-Gi1/&β;1/&γ;2
19.23	Single	6Z4S	SR48692	6Z4S-NTS₁-SR48692
19.23	Single	7BB7	Acyclovir triphosphate	7BB7-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
19.23	Single	7C4S	S1P	7C4S-S1P₃-S1P
19.23	Single	7EW3	S1P	7EW3-S1P₃-S1P-Gi1/&β;1/&γ;2
19.23	Single	7LD3	Adenosine	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
19.23	Single	7VFX	fMLF	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
19.23	Single	7VV0	PAMP-12	7VV0-MRGPRX2-PAMP-12
19.23	Single	7VV4	Cortistatin-14	7VV4-MRGPRX2-Cortistatin-14
19.23	Single	7WIG	L-054,264	7WIG-SST2-L-054,264-Gi1/&β;1/&γ;2
19.23	Single	7Y26	Octreotide	7Y26-SST2-Octreotide-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
19.23	Single	7Y27	Somatostatin-14	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
19.23	Single	8DZR	GR89,696	8DZR-κ-GR89,696-chim(NtGi2-Gt3)/&β;1/&γ;2
19.23	Single	8GNE	KW-6356	8GNE-A_2A-KW-6356-Na
19.23	Single	8ID9	Eicosapentaenoic acid	8ID9-FFA4 (GPR120)-Eicosapentaenoic acid-Gi1/&β;1/&γ;2
19.23	Single	8KFX	LMD-009	8KFX-CCR8-LMD-009-Gi1/&β;1/&γ;2
19.23	Single	8QOT	Nanobody E	8QOT-μ-Nanobody E
19.23	Consensus	a1_on_allo	Orthosteric Ligand	7LD3-A₁-Adenosine-PubChem 25263603-Gi2/&β;1/&γ;2
19.23	Consensus	adrenergic_off	Orthosteric Ligand	beta_off alpha_off
19.23	Consensus	d1_on	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
19.23	Consensus	gs_sst	Orthosteric Ligand	7Y27-SST2-Somatostatin-14-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
19.05	Single	8A2O	Theophylline	8A2O-A_2A-Theophylline-Na
19.05	Consensus	glucagon_on	Orthosteric Ligand	gip_on glu_on secretin_on ghrh_on glp_on
18.75	Single	6PT2	KGCHM07	6PT2-δ-KGCHM07
18.75	Single	7T6T	fMLFII	7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
18.75	Single	8XZG	Apelin-13	8XZG-Apelin-Apelin-13-Gi1/&β;1/&γ;2
18.75	Consensus	gi_chemerin	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
18.60	Consensus	class-b1_on	Orthosteric Ligand	glucagon_on calcitonin_on vip-pacap_on pth_on crf_on
18.52	Single	3P0G	BI167107	3P0G-β₂-BI167107
18.52	Single	4DJH	JDTic	4DJH-κ-JDTic
18.52	Single	4IAQ	Dihydroergotamine	4IAQ-5-HT_1B-Dihydroergotamine
18.52	Single	5V57	TC114	5V57-SMO-TC114
18.52	Single	5ZBH	BMS-193885	5ZBH-Y₁-BMS-193885
18.52	Single	6E59	L-760735	6E59-NK₁-L-760735
18.52	Single	6GT3	Imaradenant	6GT3-A_2A-Imaradenant-Na
18.52	Single	6H7J	Isoprenaline	6H7J-β₁-Isoprenaline
18.52	Single	6J20	Aprepitant	6J20-NK₁-Aprepitant
18.52	Single	6KO5	PubChem 57400002	6KO5-Ghrelin-PubChem 57400002
18.52	Single	6NI3	BI167107	6NI3-β₂-BI167107-Gs/&β;1/&γ;2
18.52	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
18.52	Single	6TQ7	SB-334867	6TQ7-OX₁-SB-334867
18.52	Single	6WGT	LSD	6WGT-5-HT_2A-LSD
18.52	Single	7E2Z	Aripiprazole	7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2
18.52	Single	7EW1	Siponimod	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
18.52	Single	7EW7	PubChem 4077460	7EW7-S1P₁-PubChem 4077460-Gi1/&β;1/&γ;2
18.52	Single	7F58	THIQ	7F58-MC₄-THIQ-Gs/&β;1/&γ;2
18.52	Single	7JJO	Isoprenaline	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2
18.52	Single	7S8M	Cortistatin-14	7S8M-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
18.52	Single	7W41	PD176252	7W41-BB₂-PD176252
18.52	Single	7WVX	Humanin	7WVX-FPR2-ALX-Humanin-Gi2/&β;1/&γ;2
18.52	Single	8DCS	Cyanopindolol	8DCS-β₁-Cyanopindolol-Gs/&β;1/&γ;2
18.52	Single	8I2G	Compound 716340	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
18.52	Single	8IHB	GSK256073	8IHB-HCA₂-GSK256073-Gi1/&β;1/&γ;2
18.52	Single	8IYW	GSK256073	8IYW-HCA₂-GSK256073-Go/&β;1/&γ;2
18.52	Single	8XBI	S3E-LysoPS	8XBI-GPR34-S3E-LysoPS
18.52	Consensus	5ht1b_on	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
18.52	Consensus	a2b_on	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
18.52	Consensus	adenosine_off	Orthosteric Ligand	a1_off a2_off
18.52	Consensus	bb2_off	Orthosteric Ligand	7W41-BB₂-PD176252
18.52	Consensus	bombesin_off	Orthosteric Ligand	bb2_off
18.52	Consensus	chemerin_on	Orthosteric Ligand	cml1_on
18.52	Consensus	cml1_on	Orthosteric Ligand	8SG1-CML1-Chemerin-9-Gi1/&β;1/&γ;2
18.52	Consensus	gi_dopamine	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
18.52	Consensus	gi_muscarinic	Orthosteric Ligand	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2 7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2 7V6A-M₄-PubChem 9864275-Gi1/&β;1/&γ;2
18.52	Consensus	gs_adenosine	Orthosteric Ligand	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2 8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2 6GDG-A_2A-NECA-Gs/&β;1/&γ;1 7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2 7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
18.52	Consensus	gs_dopamine	Orthosteric Ligand	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2 7CKX-D₁-A77636-Gs/&β;1/&γ;2 7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2 7CKY-D₁-PW0464-Gs/&β;1/&γ;2 8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2 7JV5-D₁-SKF81297-Gs/&β;1/&γ;2 7JVP-D₁-SKF83959-Gs/&β;1/&γ;2 7X2D-D₁-Tavapadon-Gs/&β;1/&γ;2 7JOZ-D₁-VFP-Gs/&β;1/&γ;2
18.52	Consensus	gs_nucleotide	Orthosteric Ligand	gs_adenosine
18.52	Consensus	kop_off	Orthosteric Ligand	4DJH-κ-JDTic
18.52	Consensus	s1p5_on	Orthosteric Ligand	7EW1-S1P₅-Siponimod-Gi1/&β;1/&γ;2
18.42	Single	8FLS	Abaloparatide	8FLS-PTH1-Abaloparatide-Gs/&β;1/&γ;2
18.18	Single	2J4Y	11-cis-Retinal	2J4Y-Rhodopsin-11-cis-Retinal
18.18	Single	5WKT	Octyl Beta-D-Glucopyranoside	5WKT-Rhodopsin-Octyl Beta-D-Glucopyranoside-Gt(CT)
18.18	Single	6ME9	Ramelteon	6ME9-MT₂-Ramelteon
18.18	Single	6MEO	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MEO-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
18.18	Single	6MET	Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4	6MET-CCR5-Envelope Glycoprotein Gp160; T-Cell Surface Glycoprotein Cd4
18.18	Single	7DW9	Acyclovir triphosphate	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
18.18	Single	8EIT	Doconexent	8EIT-FFA1 (GPR40)-Doconexent-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
18.18	Single	8HA0	PTH	8HA0-PTH1-PTH-chim(NtGi1-Gs)/&β;1/&γ;2
18.18	Single	8HNK	CXCL11	8HNK-CXCR3-CXCL11-Gi1/&β;1/&γ;2
18.18	Single	8J21	Butyric acid	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
18.18	Single	8JRV	Glucagon	8JRV-Glucagon-Glucagon-Arrestin2
18.18	Consensus	ccr1_on	Orthosteric Ligand	7VL9-CCR1-CCL15(26-92)-Gi1/&β;1/&γ;2
18.18	Consensus	ffa3_on	Orthosteric Ligand	8J21-FFA3-Butyric acid-Gi1/&β;1/&γ;2
18.18	Consensus	v2_on	Orthosteric Ligand	7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
17.95	Single	7V35	Peptide-20	7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2
17.95	Single	7VVM	PTH	7VVM-PTH1-PTH-Gs/&β;1/&γ;2
17.95	Single	8JIP	MEDI0382	8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2
17.86	Single	2YCX	Cyanopindolol	2YCX-β₁-Cyanopindolol
17.86	Single	4AMI	Bucindolol	4AMI-β₁-Bucindolol
17.86	Single	4LDE	BI167107	4LDE-β₂-BI167107
17.86	Single	4N4W	SANT-1	4N4W-SMO-SANT-1
17.86	Single	4PY0	2MeSATP	4PY0-P2Y₁₂-2MeSATP
17.86	Single	5F8U	Cyanopindolol	5F8U-β₁-Cyanopindolol
17.86	Single	6ME6	2-Phenylmelatonin	6ME6-MT₂-2-Phenylmelatonin
17.86	Single	6MXT	Salmeterol	6MXT-β₂-Salmeterol
17.86	Single	6TKO	Arformoterol	6TKO-β₁-Arformoterol-Arrestin2
17.86	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
17.86	Single	6W2Y	PubChem 23727970	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
17.86	Single	6XBL	Cholesterol	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
17.86	Single	6XOX	Orforglipron	6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2
17.86	Single	7DFP	Spiperone	7DFP-D₂-Spiperone
17.86	Single	7EO4	BAF312	7EO4-S1P₁-BAF312-Gi1/&β;1/&γ;2
17.86	Single	7L1V	PubChem 155491009	7L1V-OX₂-PubChem 155491009-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.86	Single	7XW9	TRH	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
17.86	Single	7XXI	2MeSADP	7XXI-P2Y₁₂-2MeSADP-Gi2/&β;1/&γ;2
17.86	Single	7Y24	Octreotide	7Y24-SST2-Octreotide-Go/&β;1/&γ;2
17.86	Single	7YIT	Nalfurafine	7YIT-κ-Nalfurafine
17.86	Single	7YMJ	Tamsulosin	7YMJ-Alpha1A-Tamsulosin
17.86	Single	8IRS	Rotigotine	8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
17.86	Single	8J22	TUG-1375	8J22-FFA2-TUG-1375-Gi1/&β;1/&γ;2
17.86	Single	8J6D	EP141	8J6D-C3a_B-EP141-Go/&β;1/&γ;2
17.86	Single	8JJ8	Formoterol	8JJ8-β₂-Formoterol
17.86	Single	8JWY	PubChem 168451710	8JWY-A_2A-PubChem 168451710
17.86	Single	8WRB	Lysophosphatidylserine	8WRB-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
17.86	Consensus	adgrg_on	Orthosteric Ligand	adgrg2_on adgrg3_on
17.86	Consensus	class-b2_on	Orthosteric Ligand	adgrg_on
17.86	Consensus	gi_class-f	Other Ligand	gi_frizzled
17.86	Consensus	gi_frizzled	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
17.86	Consensus	go_5ht	Orthosteric Ligand	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2 7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
17.86	Consensus	gs_trh	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
17.86	Consensus	nts1_off	Orthosteric Ligand	6Z4Q-NTS₁-SR142948A 6Z4S-NTS₁-SR48692
17.86	Consensus	nts_off	Orthosteric Ligand	nts1_off
17.86	Consensus	opioid_off	Orthosteric Ligand	kop_off mop_off nop_off dop_off
17.86	Consensus	trh_on	Orthosteric Ligand	7XW9-TRH-TRH-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
17.78	Consensus	gs_class-b1	Orthosteric Ligand	gs_glucagon gs_vip-pacap gs_pth gs_calcitonin gs_crf
17.65	Single	7V9M	Somatoliberin	7V9M-GHRH (SV1)-Somatoliberin-Gs/&β;1/&γ;2
17.65	Single	8E3Z	VIP	8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2
17.65	Single	8IOD	PG-901	8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
17.65	Consensus	gs_bradykinin	Orthosteric Ligand	7F2O-BK₂-Bradykinin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
17.39	Single	4MQT	LY2119620	4MQT-M₂-Iperoxo-LY2119620
17.39	Single	5TE5	20-Methanoretinal	5TE5-Rhodopsin-20-Methanoretinal
17.39	Single	6HLL	CP99994	6HLL-NK₁-CP99994
17.39	Single	6I9K	9-cis-Retinal	6I9K-Rhodopsin-9-cis-Retinal
17.39	Single	6QNO	All-trans-retinal	6QNO-Rhodopsin-All-trans-retinal-Gi1/&β;1/&γ;1
17.39	Single	6TQ4	PubChem 16046844	6TQ4-OX₁-PubChem 16046844-Na
17.39	Single	7D76	Beclomethasone	7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
17.39	Single	7TRP	LY2033298	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
17.39	Single	7XT9	Serotonin	7XT9-5-HT₄-Serotonin-Gs/&β;1/&γ;2
17.39	Single	7XTA	Serotonin	7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2
17.39	Single	8EF6	Morphine	8EF6-μ-Morphine-Gi1/&β;1/&γ;2
17.39	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
17.39	Single	8H8J	Lodoxamide	8H8J-GPR35-Lodoxamide-Ca-chim(NtGi1L-G13)/&β;1/&γ;2
17.39	Single	8U4R	REGN7663-Fab	8U4R-CXCR4-REGN7663-Fab-Cholesterol
17.39	Consensus	go_adhesion	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
17.39	Consensus	go_class-b2	Orthosteric Ligand	go_adhesion
17.39	Consensus	m4_on_allo	Other Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
17.39	Consensus	ox1_off_allo	Orthosteric Ligand	6TOD-OX₁-EMPA-Na 6TOS-OX₁-GSK1059865-Na 6TQ4-OX₁-PubChem 16046844-Na 6TO7-OX₁-Suvorexant-Na
17.24	Single	2YCZ	Iodocyanopindolol	2YCZ-β₁-Iodocyanopindolol
17.24	Single	4NC3	Ergotamine	4NC3-5-HT_2B-Ergotamine
17.24	Single	5UNG	PubChem 15780052	5UNG-AT₂-PubChem 15780052
17.24	Single	6G79	Donitriptan	6G79-5-HT_1B-Donitriptan-Go/&β;1/&γ;2
17.24	Single	6M1H	Maxadilan	6M1H-PAC₁-Maxadilan-Gs/&β;1/&γ;2
17.24	Single	7JVR	Bromoergocryptine	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2
17.24	Single	7QVM	Oxytocin	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
17.24	Single	8ID8	TUG-891	8ID8-FFA4 (GPR120)-TUG-891-Gi1/&β;1/&γ;2
17.24	Single	8T3O	TUG-891	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
17.24	Consensus	class-a_on	Orthosteric Ligand	sensory_on amine_on lipid_on nucleotide_on peptide_on protein_on hcar_on steroid_on melatonin_on
17.24	Consensus	ffa4_on_allo	Orthosteric Ligand	8T3O-FFA4-TUG-891-2Y5-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
17.24	Consensus	ot_on	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
17.14	Single	6FJ3	PTH	6FJ3-PTH1-PTH
17.14	Single	7XV3	Lysophosphatidylserine	7XV3-GPR174-Lysophosphatidylserine-chim(NtGi1-Gs)/&β;1/&γ;2
17.14	Single	8E3X	PACAP27	8E3X-PAC₁-PACAP27-Gs/&β;1/&γ;2
17.07	Single	6E3Y	Calcitonin gene-related peptide-1	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
17.07	Single	8JIU	SAR425899	8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2
16.67	Single	3NY9	PubChem 913103	3NY9-β₂-PubChem 913103
16.67	Single	3ODU	IT1t	3ODU-CXCR4-IT1t
16.67	Single	4S0V	Suvorexant	4S0V-OX₂-Suvorexant
16.67	Single	5WS3	EMPA	5WS3-OX₂-EMPA
16.67	Single	6LMK	Glucagon	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2
16.67	Single	6ME2	Ramelteon	6ME2-MT₁-Ramelteon
16.67	Single	6PWC	Neurotensin	6PWC-NTS₁-Neurotensin-Arrestin2
16.67	Single	6RZ6	ONO-2570366	6RZ6-CysLT₂-ONO-2570366
16.67	Single	6TOD	EMPA	6TOD-OX₁-EMPA-Na
16.67	Single	6TPJ	Suvorexant	6TPJ-OX₂-Suvorexant
16.67	Single	6UVA	Adrenomedullin-2	6UVA-CT Like (AM2)-Adrenomedullin-2-Gs/&β;1/&γ;2; RAMP3
16.67	Single	6XBJ	Cholesterol	6XBJ-SMO-Cholesterol-Gi1/&β;1/&γ;2
16.67	Single	7BR3	Elagolix	7BR3-GnRH₁-Elagolix
16.67	Single	7F1O	Dopamine	7F1O-D₁-Dopamine-GDP; Mg-Gs/&β;1/&γ;2
16.67	Single	7LD4	Adenosine	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
16.67	Single	7SRR	LSD	7SRR-5-HT_2B-LSD-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
16.67	Single	7T94	PubChem 57664406	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
16.67	Single	7TUZ	7alpha,25-dihydroxycholesterol	7TUZ-GPR183-7alpha,25-dihydroxycholesterol-Gi1/&β;1/&γ;2
16.67	Single	7VDL	Cortistatin-14	7VDL-MRGPRX2-Cortistatin-14-Gi1/&β;1/&γ;2
16.67	Single	7VUJ	JNJ-63533054	7VUJ-GPR139-JNJ-63533054-GDP-chim(Gs-CtGq)/&β;1/&γ;2
16.67	Single	7VV5	C48/80	7VV5-MRGPRX2-C48/80-Gi1/&β;1/&γ;2
16.67	Single	7XN9	L-054,522	7XN9-SST2-L-054,522
16.67	Single	7XRR	Lemborexant	7XRR-OX₂-Lemborexant
16.67	Single	7XT8	Serotonin	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
16.67	Single	7XY6	PubChem 11717831	7XY6-A_2B-PubChem 11717831-chim(NtGi1-Gs)/&β;1/&γ;2
16.67	Single	8DU3	PubChem 105526064	8DU3-A_2A-PubChem 105526064
16.67	Single	8GGF	Epinephrine	8GGF-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
16.67	Single	8HMP	PubChem 69921479	8HMP-GPR52-PubChem 69921479-Gs/&β;1/&γ;2
16.67	Single	8J20	Valeric acid	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
16.67	Single	8JLR	A77636	8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2
16.67	Single	8SAI	1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine	8SAI-GPR34-1-oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine-Gi1/&β;1/&γ;2
16.67	Consensus	a1_on	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
16.67	Consensus	a2a_off_allo	Orthosteric Ligand	6ZDR-A_2A-HMS1413f12-Na 6GT3-A_2A-Imaradenant-Na 8CU7-A_2A-LJ-4517-Na 5OLV-A_2A-LUAA41063-Na 5N2R-A_2A-PubChem 92460631; psb36-Na 5MZJ-A_2A-Theophylline-Na 5OLO-A_2A-Tozadenant-Na 5OLH-A_2A-Vipadenant-Na 5NM4-A_2A-ZM241385-Na 8GNE-A_2A-KW-6356-Na 8JWZ-A_2A-AB928-Na 5MZP-A_2A-Caffeine-Na 8CIC-A_2A-Etrumadenant-Na
16.67	Consensus	alpha2_off	Orthosteric Ligand	alpha2a_off alpha2c_off
16.67	Consensus	class-d_off	Orthosteric Ligand	ste2_off
16.67	Consensus	class-f_off	Orthosteric Ligand	smo_off
16.67	Consensus	cxcr1_on	Orthosteric Ligand	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
16.67	Consensus	ffa3_on_allo	Orthosteric Ligand	8J20-FFA3-Valeric acid-AR420626-Gi1/&β;1/&γ;2
16.67	Consensus	fpr1-alx_on	Orthosteric Ligand	7VFX-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2 7T6T-FPR1-ALX-fMLFII-Gi1/&β;1/&γ;2
16.67	Consensus	gi_nucleotide	Orthosteric Ligand	7LD4-A₁-Adenosine-Gi2/&β;1/&γ;2
16.67	Consensus	gnrh1_off	Orthosteric Ligand	7BR3-GnRH₁-Elagolix
16.67	Consensus	go_class-b1	Orthosteric Ligand	go_crf
16.67	Consensus	go_crf	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
16.67	Consensus	go_vasopressin	Orthosteric Ligand	7QVM-OT-Oxytocin-chim(NtGi1-Go-CtGq)/&β;1/&γ;2
16.67	Consensus	orexin_off	Orthosteric Ligand	ox2_off ox1_off
16.67	Consensus	protein_on	Orthosteric Ligand	ccr_on chemokine_on gphr_on chemerin_on
16.22	Single	6WZG	Secretin	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
16.22	Single	7VVK	PTH	7VVK-PTH1-PTH-Gs/&β;1/&γ;2
16.22	Single	7VVL	PTH	7VVL-PTH1-PTH-Gs/&β;1/&γ;2
16.22	Consensus	crf_on	Orthosteric Ligand	crf2_on crf1_on
16.13	Single	4AMJ	(S)-Carvedilol	4AMJ-β₁-(S)-Carvedilol
16.13	Single	5UNF	PubChem 15780052	5UNF-AT₂-PubChem 15780052
16.13	Single	7QA8	Peptide	7QA8-STE2-Peptide
16.13	Single	7QA8	Peptide	7QA8-STE2-Peptide
16.13	Single	7T6U	CGEN-855A	7T6U-FPR2-ALX-CGEN-855A-Gi1/&β;1/&γ;2
16.13	Single	7XMR	Somatostatin-14	7XMR-SST2-Somatostatin-14-Gi1/&β;1/&γ;2
16.13	Single	8DCR	Dobutamine	8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
16.13	Single	8J6R	MK6892	8J6R-HCA₂-MK6892-Gi1/&β;1/&γ;2
16.13	Consensus	class-d_off	Orthosteric Ligand	ste2_off
16.00	Single	4DKL	Beta-funaltrexamine	4DKL-μ-Beta-funaltrexamine
16.00	Single	4ZJC	SB-674042	4ZJC-OX₁-SB-674042
16.00	Single	6AQF	ZM241385	6AQF-A_2A-ZM241385
16.00	Single	6FK8	PubChem 132473035	6FK8-Rhodopsin-PubChem 132473035
16.00	Single	6IQL	L745870	6IQL-D₄-L745870
16.00	Single	6TOS	GSK1059865	6TOS-OX₁-GSK1059865-Na
16.00	Single	6TPK	Retosiban	6TPK-OT-Retosiban
16.00	Single	6V9S	GTPL11403	6V9S-OX₁-GTPL11403
16.00	Single	6WJC	Muscarinic toxin 7	6WJC-M₁-Atropine-Muscarinic toxin 7
16.00	Single	6ZIN	SR48692	6ZIN-NTS₁-SR48692
16.00	Single	7BB6	Acyclovir triphosphate	7BB6-V₂-Acyclovir triphosphate-Gs/&β;1/&γ;2
16.00	Single	7CKW	Fenoldopam	7CKW-D₁-Fenoldopam-Gs/&β;1/&γ;2
16.00	Single	7CKZ	Dopamine	7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
16.00	Single	7F0T	Dopamine	7F0T-D₁-Dopamine-Gs/&β;1/&γ;2
16.00	Single	7F1Z	Dopamine	7F1Z-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
16.00	Single	7F61	PF-03654746	7F61-H₃-PF-03654746-Cholesterol
16.00	Single	7SR8	TAK-925	7SR8-OX₂-TAK-925-chim(NtGi1L-Gs-CtGq)/&β;1/&γ;2
16.00	Single	7VV6	C48/80	7VV6-MRGPRX2-C48/80
16.00	Single	7WC9	PubChem 162421364	7WC9-5-HT_2A-PubChem 162421364
16.00	Single	7WVU	fMLF	7WVU-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
16.00	Single	7YK6	PubChem 138319674	7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
16.00	Single	8JER	Acipimox	8JER-HCA₂-Acipimox-Go/&β;1/&γ;2
16.00	Single	8JIM	MMF	8JIM-HCA₂-MMF-Gi1/&β;1/&γ;2
16.00	Single	8JLQ	Fenoldopam	8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2
16.00	Single	8K4N	VF0	8K4N-GPR34-VF0-Gi1/&β;1/&γ;2
16.00	Single	8UO2	Epinephrine	8UO2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
16.00	Single	8X7A	Treprostinil	8X7A-I2-Treprostinil-Gs/&β;1/&γ;2
16.00	Consensus	5ht5_on	Orthosteric Ligand	5ht5a_on
16.00	Consensus	5ht5a_on	Orthosteric Ligand	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2 7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2 7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
16.00	Consensus	cb1_off	Orthosteric Ligand	5TGZ-CB₁-AM6538 5U09-CB₁-Taranabant
16.00	Consensus	d1_on_allo	Orthosteric Ligand	7LJC-D₁-PubChem 86764103-Mevidalen-Gs/&β;1/&γ;2 7CKZ-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
16.00	Consensus	h3_on_allo	Orthosteric Ligand	7F61-H₃-PF-03654746-Cholesterol
16.00	Consensus	m1_off_allo	Other Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
16.00	Consensus	ot_off	Orthosteric Ligand	6TPK-OT-Retosiban
16.00	Consensus	ox1_off	Orthosteric Ligand	6TOT-OX₁-Lemborexant 6TP4-OX₁-ACT-462206 6TP6-OX₁-Filorexant 6V9S-OX₁-GTPL11403 6TP3-OX₁-Nemorexant 6TQ6-OX₁-PubChem 145714283 6TQ7-OX₁-SB-334867 6TQ9-OX₁-SB-408124 4ZJC-OX₁-SB-674042 4ZJ8-OX₁-Suvorexant
16.00	Consensus	sensory_off	Orthosteric Ligand	opsin_off
16.00	Consensus	vasopressin-ot_off	Orthosteric Ligand	ot_off
15.79	Single	6PB0	Urocortin	6PB0-CRF₁-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
15.79	Single	7RBT	Tirzepatide	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
15.79	Single	7TS0	Urocortin	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
15.79	Consensus	gs_crf	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
15.62	Single	5XJM	(Sar1,Ile8)-Angiotensin II	5XJM-AT₂-(Sar1,Ile8)-Angiotensin II
15.38	Single	2Y04	Salbutamol	2Y04-β₁-Salbutamol
15.38	Single	2YCY	Cyanopindolol	2YCY-β₁-Cyanopindolol
15.38	Single	4X1H	Nonyl Beta-D-Glucopyranoside	4X1H-Rhodopsin-Nonyl Beta-D-Glucopyranoside-Gt(CT)
15.38	Single	4YAY	ZD-7155	4YAY-AT₁-ZD-7155
15.38	Single	5NDD	AZ8838; Na	5NDD-PAR2-AZ8838; Na
15.38	Single	5UEN	DU172	5UEN-A₁-DU172
15.38	Single	5ZKP	Foropafant (SR27417)	5ZKP-PAF-Foropafant (SR27417)
15.38	Single	6FK7	PubChem 132473034	6FK7-Rhodopsin-PubChem 132473034
15.38	Single	6FKC	PubChem 132473039	6FKC-Rhodopsin-PubChem 132473039
15.38	Single	6FKD	PubChem 137349183	6FKD-Rhodopsin-PubChem 137349183
15.38	Single	6LPB	PACAP	6LPB-PAC₁-PACAP-Gs/&β;1/&γ;1
15.38	Single	6ORV	TT-OAD2	6ORV-GLP-1-TT-OAD2-Gs/&β;1/&γ;2
15.38	Single	6PRZ	(S)-Alprenolol	6PRZ-β₂-(S)-Alprenolol
15.38	Single	6PS1	Timolol	6PS1-β₂-Timolol
15.38	Single	6Z10	PubChem 154585554	6Z10-Succinate-PubChem 154585554
15.38	Single	7BU7	BI167107	7BU7-β₁-BI167107
15.38	Single	7DB6	Ramelteon	7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
15.38	Single	7JVQ	Apomorphine	7JVQ-D₁-Apomorphine-Gs/&β;1/&γ;2
15.38	Single	7PP1	Selatogrel	7PP1-P2Y₁₂-Selatogrel
15.38	Single	7S0G	Isoprenaline	7S0G-β₁-Isoprenaline-chim(Gi1-CtGs)/&β;1/&γ;2
15.38	Single	7T6V	fMLFII	7T6V-FPR2-ALX-fMLFII-Gi1/&β;1/&γ;2
15.38	Single	7UM6	Lisuride	7UM6-5-HT_5A-Lisuride-chim(NtGi1-Go)/&β;1/&γ;2
15.38	Single	7VH0	Ramelteon	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
15.38	Single	7X2C	Fenoldopam	7X2C-D₁-Fenoldopam-Fenoldopam-Gs/&β;1/&γ;2
15.38	Single	7XJH	Isoproterenol	7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
15.38	Single	8CIC	Etrumadenant	8CIC-A_2A-Etrumadenant-Na
15.38	Single	8CU6	LJ-4517	8CU6-A_2A-LJ-4517
15.38	Single	8CU7	LJ-4517	8CU7-A_2A-LJ-4517-Na
15.38	Single	8GEH	Epinephrine	8GEH-β₂-Epinephrine-Gs/&β;1/&γ;2
15.38	Single	8GGB	Epinephrine	8GGB-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
15.38	Single	8IC0	Interleukin-8	8IC0-CXCR1-Interleukin-8-Gi1/&β;1/&γ;2
15.38	Single	8JII	Niacin	8JII-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
15.38	Single	8JLZ	ST1936	8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
15.38	Single	8JT8	(R)-IHCH-7179	8JT8-5-HT_2A-(R)-IHCH-7179
15.38	Consensus	5ht6_on	Orthosteric Ligand	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2
15.38	Consensus	adenosine_on	Orthosteric Ligand	a1_on a2_on
15.38	Consensus	hca3_on	Orthosteric Ligand	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
15.38	Consensus	nucleotide_on	Orthosteric Ligand	adenosine_on
15.38	Consensus	p2y12_off	Orthosteric Ligand	4NTJ-P2Y₁₂-AZD1283 7PP1-P2Y₁₂-Selatogrel
15.38	Consensus	paf_off	Orthosteric Ligand	5ZKQ-PAF-ABT-491 5ZKP-PAF-Foropafant (SR27417)
15.38	Consensus	smo_off	Orthosteric Ligand	5L7I-SMO-Vismodegib 4O9R-SMO-Cyclopamine 4QIM-SMO-PubChem 24905375 4JKV-SMO-Taladegib (LY2940680)
15.38	Consensus	tachykinin_off	Orthosteric Ligand	nk1_off
15.15	Single	6VN7	PACAP	6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
15.15	Single	7VVN	PTH	7VVN-PTH1-PTH-Gs/&β;1/&γ;2
15.15	Consensus	mc5_on	Orthosteric Ligand	8INR-MC₅-Alpha-MSH-Ca-chim(NtGi1-Gs)/&β;1/&γ;2 8IOD-MC₅-PG-901-Ca-chim(NtGi1-Gs)/&β;1/&γ;2
15.00	Single	8WCC	Cyclohexylammonium ion	8WCC-TA1-Cyclohexylammonium ion
14.81	Single	2Y03	Isoprenaline	2Y03-β₁-Isoprenaline
14.81	Single	4NTJ	AZD1283	4NTJ-P2Y₁₂-AZD1283
14.81	Single	4WW3	All-trans-retinal	4WW3-Rhodopsin-All-trans-retinal
14.81	Single	4ZJ8	Suvorexant	4ZJ8-OX₁-Suvorexant
14.81	Single	5OM4	PubChem 135566609	5OM4-A_2A-PubChem 135566609-Na
14.81	Single	5TVN	LSD	5TVN-5-HT_2B-LSD
14.81	Single	5WQC	EMPA	5WQC-OX₂-EMPA
14.81	Single	5XPR	Bosentan	5XPR-ET_B-Bosentan
14.81	Single	6E67	BI167107	6E67-β₂-BI167107-Gs (fused)
14.81	Single	6GDG	NECA	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
14.81	Single	6KUW	PubChem 57213234	6KUW-α_2c-PubChem 57213234
14.81	Single	6ME8	2-Phenylmelatonin	6ME8-MT₂-2-Phenylmelatonin
14.81	Single	6PS3	(S)-Carvedilol	6PS3-β₂-(S)-Carvedilol
14.81	Single	6RZ4	Pranlukast	6RZ4-CysLT₁-Pranlukast-Na
14.81	Single	6TO7	Suvorexant	6TO7-OX₁-Suvorexant-Na
14.81	Single	7BVQ	(S)-Carazolol	7BVQ-β₁-(S)-Carazolol
14.81	Single	7CFN	INT-777	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2
14.81	Single	7S0F	Isoprenaline	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2
14.81	Single	7SBF	PZM21	7SBF-μ-PZM21-Gi1/&β;1/&γ;2
14.81	Single	7WC6	LSD	7WC6-5-HT_2A-LSD
14.81	Single	7XKA	Epinephrine	7XKA-β₂-Epinephrine
14.81	Single	8C9W	Etrumadenant	8C9W-A_2A-Etrumadenant
14.81	Single	8EFB	Oliceridine	8EFB-μ-Oliceridine-Gi1/&β;1/&γ;2
14.81	Single	8IHJ	Acifran	8IHJ-HCA₃-Acifran-Gi1/&β;1/&γ;2
14.81	Single	8IZ4	Lysophosphatidylserine	8IZ4-GPR34-Lysophosphatidylserine-Gi1/&β;1/&γ;2
14.81	Single	8J19	PubChem 127045422	8J19-GPR84-PubChem 127045422-Gi1/&β;1/&γ;2
14.81	Single	8J6J	GSK256073	8J6J-HCA₂-GSK256073-Gi1/&β;1/&γ;2
14.81	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
14.81	Single	8UNY	Epinephrine	8UNY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
14.81	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
14.81	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
14.81	Consensus	5ht2b_off	Orthosteric Ligand	6DRZ-5-HT_2B-Methysergide 6DRX-5-HT_2B-Lisuride
14.81	Consensus	a1_off	Orthosteric Ligand	5UEN-A₁-DU172 5N2S-A₁-PSB36
14.81	Consensus	a2a_on	Orthosteric Ligand	6GDG-A_2A-NECA-Gs/&β;1/&γ;1
14.81	Consensus	alpha2c_off	Orthosteric Ligand	6KUW-α_2c-PubChem 57213234
14.81	Consensus	beta2_on	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
14.81	Consensus	beta3_on	Orthosteric Ligand	7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2
14.81	Consensus	d2_on	Orthosteric Ligand	7JVR-D₂-Bromoergocryptine-Gi1/&β;1/&γ;2 8IRS-D₂-Rotigotine-Gi1/&β;1/&γ;2
14.81	Consensus	gi_adrenergic	Orthosteric Ligand	7S0F-β₁-Isoprenaline-Gi1/&β;1/&γ;2 6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
14.81	Consensus	gs_adrenergic	Orthosteric Ligand	3SN6-β₂-BI167107-Gs/&β;1/&γ;2 7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2 7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2 7XJH-β₃-Isoproterenol-Gs/&β;1/&γ;2 7DH5-β₃-Mirabegron-Gs/&β;1/&γ;2 7XJI-β₃-Solabegron-Gs/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2 7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
14.71	Single	6WI9	Secretin	6WI9-Secretin-Secretin-Gs/&β;1/&γ;2
14.71	Single	7WUI	IP15	7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
14.71	Single	8J6I	MK6892	8J6I-HCA₂-MK6892-Gi1/&β;1/&γ;2
14.63	Single	8JIT	MEDI0382	8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2
14.63	Consensus	gs_vip-pacap	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
14.29	Single	2YDV	NECA	2YDV-A_2A-NECA
14.29	Single	3PDS	Hydroxybenzylisoproterenol	3PDS-β₂-Hydroxybenzylisoproterenol
14.29	Single	4LDL	Hydroxybenzylisoproterenol	4LDL-β₂-Hydroxybenzylisoproterenol
14.29	Single	4UHR	CGS21680	4UHR-A_2A-CGS21680
14.29	Single	5A8E	7-Methylcyanopindolol	5A8E-β₁-7-Methylcyanopindolol-Na
14.29	Single	5G53	NECA	5G53-A_2A-NECA-Gs
14.29	Single	5MZJ	Theophylline	5MZJ-A_2A-Theophylline-Na
14.29	Single	5X93	K-8794	5X93-ET_B-K-8794
14.29	Single	6J21	Aprepitant	6J21-NK₁-Aprepitant
14.29	Single	6N48	BI167107	6N48-β₂-BI167107-PubChem 138454256
14.29	Single	6Z4Q	SR142948A	6Z4Q-NTS₁-SR142948A
14.29	Single	7AUE	Setmelanotide	7AUE-MC₄-Setmelanotide-chim(NtGi1L-Gs)/&β;1/&γ;2
14.29	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
14.29	Single	7R0C	Acyclovir triphosphate	7R0C-V₂-Acyclovir triphosphate-Arrestin2
14.29	Single	7T2H	Lofentanil	7T2H-μ-Lofentanil-Gi1/&β;1/&γ;2
14.29	Single	7TUY	GSK682753A	7TUY-GPR183-GSK682753A
14.29	Single	7U2L	PubChem 163201242	7U2L-μ-PubChem 163201242-Gi1/&β;1/&γ;2
14.29	Single	7Y35	Abaloparatide	7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2
14.29	Single	8E3Y	PACAP27	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2
14.29	Single	8G05	6-OAU	8G05-GPR84-6-OAU-Gi1/&β;1/&γ;2
14.29	Single	8HDO	BAY 60-6583	8HDO-A_2B-BAY 60-6583-Gs/&β;1/&γ;2
14.29	Single	8IHH	LUF6283	8IHH-HCA₂-LUF6283-Gi1/&β;1/&γ;2
14.29	Single	8IRU	Rotigotine	8IRU-D₄-Rotigotine-chim(NtGi1-Gs-CtGi1)/&β;1/&γ;2
14.29	Single	8JT6	(R)-IHCH-7179	8JT6-5-HT_1A-(R)-IHCH-7179-Gi1/&β;1/&γ;2
14.29	Single	8JXV	Clozapine	8JXV-H₄-Clozapine-Gi1/&β;1/&γ;2
14.29	Single	8KH5	Lysophosphatidylserine	8KH5-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
14.29	Single	8PWN	Theophylline	8PWN-A_2A-Theophylline
14.29	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
14.29	Single	8X16	Piclidenoson	8X16-A3A-Piclidenoson-Gi1/&β;1/&γ;2
14.29	Consensus	5ht5_off	Orthosteric Ligand	5ht5a_off
14.29	Consensus	a2_on	Orthosteric Ligand	a2a_on a2b_on
14.29	Consensus	bk1_on	Orthosteric Ligand	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
14.29	Consensus	dopamine_off	Orthosteric Ligand	d3_off d2_off d4_off
14.29	Consensus	nk1_off	Orthosteric Ligand	6J20-NK₁-Aprepitant 6HLL-NK₁-CP99994 6E59-NK₁-L-760735
14.29	Consensus	npy1_off	Orthosteric Ligand	5ZBH-Y₁-BMS-193885 5ZBQ-Y₁-UR-MK-299
14.29	Consensus	relaxin_on	Orthosteric Ligand	rxfp4_on
14.29	Consensus	sst4_on	Orthosteric Ligand	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
13.89	Single	7CZ5	Somatoliberin	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
13.89	Single	7D3S	Secretin	7D3S-Secretin-Secretin-Gs/&β;1/&γ;2
13.89	Single	7FIY	Tirzepatide	7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
13.89	Single	7QBI	Alpha-factor mating pheromone	7QBI-STE2-Alpha-factor mating pheromone
13.89	Single	7RA3	GIP	7RA3-GIP-GIP-chim(NtGi1-Gs)/&β;1/&γ;2
13.89	Single	7VAB	Non-Acylated Tirzepatide	7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2
13.89	Consensus	class-d_on	Orthosteric Ligand	ste2_on
13.89	Consensus	gs_vasopressin-ot	Orthosteric Ligand	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7DW9-V₂-Acyclovir triphosphate-chim(NtGi1-Gs)/&β;1/&γ;2
13.79	Single	6A93	Risperidone	6A93-5-HT_2A-Risperidone
13.79	Single	6DRY	Methylergonovine	6DRY-5-HT_2B-Methylergonovine
13.79	Single	6H7O	Cyanopindolol	6H7O-β₁-Cyanopindolol
13.79	Single	6RZ7	ONO-2570366	6RZ7-CysLT₂-ONO-2570366
13.79	Single	7EXD	Lasmiditan	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
13.79	Single	7K15	MKD046	7K15-BLT₁-MKD046-Na
13.79	Single	7T6B	S1P	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
13.79	Single	7WCM	MBX-2982	7WCM-GPR119-MBX-2982-Gs/&β;1/&γ;2
13.79	Single	7WCN	AR231453	7WCN-GPR119-AR231453-Gs/&β;1/&γ;2
13.79	Single	7XMT	J-2156	7XMT-SST4-J-2156-Gi1/&β;1/&γ;2
13.79	Single	7XY7	NECA	7XY7-A_2B-NECA-chim(NtGi1-Gs)/&β;1/&γ;2
13.79	Single	7XZ5	Lysophosphatidylcholine	7XZ5-GPR119-Lysophosphatidylcholine-Gs/&β;1/&γ;2
13.79	Single	8IRV	Rotigotine	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
13.79	Single	8JWZ	AB928	8JWZ-A_2A-AB928-Na
13.79	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
13.79	Consensus	5ht1f_on	Orthosteric Ligand	7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2
13.79	Consensus	blt1_off	Orthosteric Ligand	7K15-BLT₁-MKD046-Na
13.79	Consensus	blt_off	Orthosteric Ligand	blt1_off
13.79	Consensus	gs_amine	Orthosteric Ligand	gs_5ht gs_adrenergic gs_dopamine gs_histamine gs_muscarinic gs_tar
13.79	Consensus	leuko_off	Orthosteric Ligand	blt_off cyslt_off
13.64	Single	3RFM	Caffeine	3RFM-A_2A-Caffeine
13.64	Single	6OT0	25(S)-Epoxycholesterol	6OT0-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
13.64	Single	8U4Q	REGN7663-Fab	8U4Q-CXCR4-REGN7663-Fab-Cholesterol-Gi1/&β;1/&γ;2
13.51	Single	6P9X	Corticoliberin	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
13.51	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
13.51	Single	7DTY	GIP	7DTY-GIP-GIP-Gs/&β;1/&γ;2
13.51	Single	7EIB	Des-Arg10-Kallidin	7EIB-BK₁-Des-Arg10-Kallidin-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
13.51	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
13.51	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
13.51	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
13.51	Consensus	gs_cgrp	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
13.33	Single	4BVN	Cyanopindolol	4BVN-β₁-Cyanopindolol-Na
13.33	Single	5UNH	PubChem 126456406	5UNH-AT₂-PubChem 126456406
13.33	Single	6H7L	Dobutamine	6H7L-β₁-Dobutamine
13.33	Single	6K1Q	IRL2500	6K1Q-ET_B-IRL2500
13.33	Single	6RZ9	ONO-2770372	6RZ9-CysLT₂-ONO-2770372
13.33	Single	7LLL	Exendin-4	7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2
13.33	Single	7MTS	ADX55164	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
13.33	Single	7U2K	C6-guano	7U2K-μ-C6-guano-Gi1/&β;1/&γ;2
13.33	Single	7UM4	AS2674723	7UM4-5-HT_5A-AS2674723
13.33	Single	7XAV	Lanreotide	7XAV-SST2-Lanreotide-Gi1/&β;1/&γ;2
13.33	Single	7XZ6	APD668	7XZ6-GPR119-APD668-Gs/&β;1/&γ;2
13.33	Single	8E9X	2-Deoxycytidine	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2
13.33	Single	8FX5	Xanomeline	8FX5-M₄-Xanomeline-Xanomeline-Gi1/&β;1/&γ;2
13.33	Single	8IQ6	Latanoprost	8IQ6-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
13.33	Single	8IUL	Latanoprost	8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
13.33	Consensus	5ht5a_off	Orthosteric Ligand	7UM4-5-HT_5A-AS2674723
13.33	Consensus	beta1_off_allo	Orthosteric Ligand	4BVN-β₁-Cyanopindolol-Na
13.33	Consensus	cyslt2_off	Orthosteric Ligand	6RZ6-CysLT₂-ONO-2570366 6RZ9-CysLT₂-ONO-2770372 6RZ8-CysLT₂-ONO-2080365
13.33	Consensus	cyslt_off	Orthosteric Ligand	cyslt2_off
13.33	Consensus	endothelin_off	Orthosteric Ligand	etb_off
13.33	Consensus	etb_off	Orthosteric Ligand	5XPR-ET_B-Bosentan 6K1Q-ET_B-IRL2500 5X93-ET_B-K-8794
13.33	Consensus	gs_lipid	Orthosteric Ligand	gs_ffa gs_prostanoid
13.16	Single	6PB1	Urocortin	6PB1-CRF₂-Urocortin-chim(NtGi1-Gs)/&β;1/&γ;2
13.16	Single	7QBC	Alpha-factor mating pheromone	7QBC-STE2-Alpha-factor mating pheromone
13.04	Single	3C9M	11-cis-Retinal	3C9M-Rhodopsin-11-cis-Retinal
13.04	Single	3OE6	IT1t	3OE6-CXCR4-IT1t
13.04	Single	6FK9	PubChem 132473036	6FK9-Rhodopsin-PubChem 132473036
13.04	Single	6LI0	GTPL9804	6LI0-GPR52-GTPL9804
13.04	Single	7D77	Hydrocortisone	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2
13.04	Single	7F23	Dopamine	7F23-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
13.04	Single	8WC6	2-Phenylethylamine	8WC6-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
13.04	Consensus	adgrg3_on	Orthosteric Ligand	7D77-ADGRG3-Hydrocortisone-Go/&β;1/&γ;2 7D76-ADGRG3-Beclomethasone-Go/&β;1/&γ;2
12.90	Single	6PT3	DPI-287	6PT3-δ-DPI-287
12.90	Single	7MTR	ADX55164	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
12.90	Single	8IYH	MK6892	8IYH-HCA₂-MK6892-Go/&β;1/&γ;2
12.90	Single	8X5Y	Astemizole	8X5Y-H₁-Astemizole
12.90	Consensus	gs_adgr	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
12.90	Consensus	gs_class-b2	Orthosteric Ligand	gs_adgr
12.90	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
12.82	Single	7TYN	Calcitonin-1	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2
12.82	Consensus	gip_on_allo	Orthosteric Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
12.50	Single	1L9H	11-cis-Retinal	1L9H-Rhodopsin-11-cis-Retinal
12.50	Single	3OE9	IT1t	3OE9-CXCR4-IT1t
12.50	Single	3PBL	Eticlopride	3PBL-D₃-Eticlopride
12.50	Single	3V2W	PubChem 51892645	3V2W-S1P₁-PubChem 51892645
12.50	Single	4O9R	Cyclopamine	4O9R-SMO-Cyclopamine
12.50	Single	5L7I	Vismodegib	5L7I-SMO-Vismodegib
12.50	Single	6FK6	PubChem 132473033	6FK6-Rhodopsin-PubChem 132473033
12.50	Single	6PGS	Geraniol	6PGS-Rhodopsin-Geraniol-Gt(CT)
12.50	Single	6PH7	Nerol	6PH7-Rhodopsin-Nerol-Gt(CT)
12.50	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
12.50	Single	7SRQ	LSD	7SRQ-5-HT_2B-LSD
12.50	Single	7UL2	SR48692	7UL2-NTS₁-SR48692-Na
12.50	Single	7XP6	Strychnine	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
12.50	Single	7XTB	Serotonin	7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2
12.50	Single	7YS6	Serotonin	7YS6-5-HT₆-Serotonin-chim(NtGi1-Gs)/&β;1/&γ;2
12.50	Single	8A2P	LUAA47070	8A2P-A_2A-LUAA47070-Na
12.50	Single	8GH1	Epinephrine	8GH1-β₂-Epinephrine
12.50	Single	8IZB	Lysophosphatidylserine	8IZB-GPR174-Lysophosphatidylserine-Gs/&β;1/&γ;2
12.50	Single	8JIL	Niacin	8JIL-HCA₂-Niacin-Gi1/&β;1/&γ;2
12.50	Single	8JIQ	Peptide-15	8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2
12.50	Single	8JLO	Ulotaront	8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2
12.50	Single	8JSO	AMPH	8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2
12.50	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
12.50	Single	8W89	PEA	8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2
12.50	Consensus	5ht4_on	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2
12.50	Consensus	class-t_on	Orthosteric Ligand	taste2_on
12.50	Consensus	d3_off	Orthosteric Ligand	3PBL-D₃-Eticlopride
12.50	Consensus	gs_class-t	Orthosteric Ligand	gs_taste
12.50	Consensus	gs_taste	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
12.50	Consensus	mt1_on	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2
12.50	Consensus	mt2_on	Orthosteric Ligand	7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
12.50	Consensus	nts1_off_allo	Orthosteric Ligand	7UL2-NTS₁-SR48692-Na
12.50	Consensus	ste2_off	Orthosteric Ligand	7QA8-STE2-Peptide
12.50	Consensus	taste2_on	Orthosteric Ligand	7XP6-T2R46-Strychnine-chim(Gs-CtGt3)/&β;1/&γ;2
12.20	Single	8JIR	SAR425899	8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2
12.12	Single	6WHC	Glu16 analog of GCG	6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
12.12	Single	7CUM	Phospholipid	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
12.12	Single	7DDZ	JNJ-31020028	7DDZ-Y₂-JNJ-31020028
12.12	Consensus	npy2_off	Orthosteric Ligand	7DDZ-Y₂-JNJ-31020028
12.00	Single	1F88	11-cis-Retinal	1F88-Rhodopsin-11-cis-Retinal
12.00	Single	1GZM	11-cis-Retinal	1GZM-Rhodopsin-11-cis-Retinal
12.00	Single	3C9L	11-cis-Retinal	3C9L-Rhodopsin-11-cis-Retinal
12.00	Single	4QIN	SAG1.5	4QIN-SMO-SAG1.5
12.00	Single	5DHH	SB-612111	5DHH-NOP-SB-612111
12.00	Single	5OLH	Vipadenant	5OLH-A_2A-Vipadenant-Na
12.00	Single	5U09	Taranabant	5U09-CB₁-Taranabant
12.00	Single	5ZKQ	ABT-491	5ZKQ-PAF-ABT-491
12.00	Single	6AKX	A4R	6AKX-CCR5-A4R
12.00	Single	6B73	PubChem 131955138	6B73-κ-PubChem 131955138
12.00	Single	6D9H	Adenosine	6D9H-A₁-Adenosine-Gi2/&β;1/&γ;2
12.00	Single	6FKB	PubChem 132473038	6FKB-Rhodopsin-PubChem 132473038
12.00	Single	6KUX	RS-79948	6KUX-α_2a-RS-79948
12.00	Single	6O3C	SAG21k	6O3C-SMO-SAG21k-Cholesterol
12.00	Single	6OBA	(S)-Alprenolol	6OBA-β₂-(S)-Alprenolol-GTPL11074
12.00	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
12.00	Single	7EJ0	L-Norepinephrine	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2
12.00	Single	7F24	Dopamine	7F24-D₁-Dopamine-GDP-Gs/&β;1/&γ;2
12.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
12.00	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
12.00	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
12.00	Single	7SRS	LSD	7SRS-5-HT_2B-LSD-Arrestin2
12.00	Single	7T6S	PubChem 24776341	7T6S-FPR2-ALX-PubChem 24776341-Gi1/&β;1/&γ;2
12.00	Single	7W0O	Elabela	7W0O-Apelin-Elabela-Gi1/&β;1/&γ;2
12.00	Single	7X2F	Dopamine	7X2F-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;2
12.00	Single	7X5H	5-CT	7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2
12.00	Single	8A6C	All-trans-retinal	8A6C-Rhodopsin-All-trans-retinal
12.00	Single	8A6D	All-trans-retinal	8A6D-Rhodopsin-All-trans-retinal
12.00	Single	8A6E	All-trans-retinal	8A6E-Rhodopsin-All-trans-retinal
12.00	Single	8EFO	PZM21	8EFO-μ-PZM21-Gi1/&β;1/&γ;2
12.00	Single	8HDP	Adenosine	8HDP-A_2B-Adenosine-Gs/&β;1/&γ;2
12.00	Single	8IHK	Acifran	8IHK-HCA₃-Acifran
12.00	Single	8IJB	Acipimox	8IJB-HCA₂-Acipimox-Gi1/&β;1/&γ;2
12.00	Single	8IW4	Spermidine	8IW4-TAAR9-Spermidine-chim(NtGi1-Gs)/&β;1/&γ;2
12.00	Single	8IWE	Spermidine	8IWE-TAAR9-Spermidine
12.00	Single	8J6L	Niacin	8J6L-HCA₂-Niacin-Gi1/&β;1/&γ;2
12.00	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
12.00	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
12.00	Single	8UO0	Epinephrine	8UO0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
12.00	Single	8UO3	Epinephrine	8UO3-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
12.00	Single	8WC4	ZH8651	8WC4-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
12.00	Single	8WCA	2-Phenylethylamine	8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
12.00	Consensus	5ht_on	Orthosteric Ligand	5ht1_on 5ht2_on 5ht4_on 5ht5_on 5ht6_on 5ht7_on
12.00	Consensus	alpha2a_off	Orthosteric Ligand	6KUX-α_2a-RS-79948
12.00	Consensus	beta2_off_allo	Orthosteric Ligand	6OBA-β₂-(S)-Alprenolol-GTPL11074
12.00	Consensus	gs_5ht	Orthosteric Ligand	7XT8-5-HT₄-Serotonin-Gs/&β;1/&γ;2 7XTB-5-HT₆-Serotonin-Gs/&β;1/&γ;2 8JLZ-5-HT₆-ST1936-Gs/&β;1/&γ;2 7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
12.00	Consensus	melatonin_on	Orthosteric Ligand	mt1_on mt2_on
12.00	Consensus	opsin_off	Orthosteric Ligand	1U19-Rhodopsin-11-cis-Retinal 2PED-Rhodopsin-9-cis-Retinal 5TE5-Rhodopsin-20-Methanoretinal
12.00	Consensus	smo_on_allo	Other Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
11.90	Consensus	pth2_on	Orthosteric Ligand	7F16-PTH2-TIP39-Gs/&β;1/&γ;2
11.54	Single	2YDO	Adenosine	2YDO-A_2A-Adenosine
11.54	Single	3OAX	11-cis-Retinal	3OAX-Rhodopsin-11-cis-Retinal
11.54	Single	3RZE	Cidoxepin	3RZE-H₁-Cidoxepin
11.54	Single	3UZC	PubChem 135566609	3UZC-A_2A-PubChem 135566609
11.54	Single	4LDO	L-Epinephrine	4LDO-β₂-L-Epinephrine
11.54	Single	4MBS	Maraviroc	4MBS-CCR5-Maraviroc
11.54	Single	4N6H	Naltrindole	4N6H-δ-Naltrindole-Na
11.54	Single	6FKA	PubChem 132473037	6FKA-Rhodopsin-PubChem 132473037
11.54	Single	6K41	Dexmedetomidine	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
11.54	Single	6PEL	Citronellol	6PEL-Rhodopsin-Citronellol-Gt(CT)
11.54	Single	6PS4	ICI 118-551	6PS4-β₂-ICI 118-551
11.54	Single	6PS5	(S)-Propranolol	6PS5-β₂-(S)-Propranolol
11.54	Single	6TPG	EMPA	6TPG-OX₂-EMPA
11.54	Single	6VI4	JDTic	6VI4-κ-JDTic
11.54	Single	6XBL	SAG	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
11.54	Single	6ZDV	PubChem 984073	6ZDV-A_2A-PubChem 984073-Na
11.54	Single	7CMU	Pramipexole	7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
11.54	Single	7CMV	PD128907	7CMV-D₃-PD128907-Gi1/&β;1/&γ;2
11.54	Single	7E33	BRL-54443	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
11.54	Single	7RAN	PubChem 164575847	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
11.54	Single	7UM7	Methylergometrine	7UM7-5-HT_5A-Methylergometrine-chim(NtGi1-Go)/&β;1/&γ;2
11.54	Single	7VOD	Cariprazine	7VOD-5-HT_2A-Cariprazine
11.54	Single	7ZBC	11-cis-Retinal	7ZBC-Rhodopsin-11-cis-Retinal
11.54	Single	7ZI0	SAG	7ZI0-SMO-SAG-Cholesterol
11.54	Single	8FCZ	11-cis-Retinal	8FCZ-Rhodopsin-11-cis-Retinal
11.54	Single	8GDZ	Epinephrine	8GDZ-β₂-Epinephrine-Gs/&β;1/&γ;2
11.54	Single	8GEG	Epinephrine	8GEG-β₂-Epinephrine-Gs/&β;1/&γ;2
11.54	Single	8GG5	Epinephrine	8GG5-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
11.54	Single	8GGK	Epinephrine	8GGK-β₂-Epinephrine
11.54	Single	8GGL	Epinephrine	8GGL-β₂-Epinephrine
11.54	Single	8GGM	Epinephrine	8GGM-β₂-Epinephrine
11.54	Single	8GGP	Epinephrine	8GGP-β₂-Epinephrine
11.54	Single	8GGQ	Epinephrine	8GGQ-β₂-Epinephrine
11.54	Single	8GGT	Epinephrine	8GGT-β₂-Epinephrine
11.54	Single	8HJ5	PubChem 139030531	8HJ5-MRGPRX1-PubChem 139030531-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
11.54	Single	8J6P	Niacin	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2
11.54	Single	8JHN	MMF	8JHN-HCA₂-MMF-Go/&β;1/&γ;2
11.54	Single	8JLK	Ulotaront	8JLK-TA1-Ulotaront-chim(NtGi1-Gs)/&β;1/&γ;2
11.54	Single	8K5C	Acipimox	8K5C-HCA₂-Acipimox
11.54	Single	8THL	Epinephrine	8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
11.54	Single	8UHB	RO5256390	8UHB-TA1-RO5256390-Gs/&β;1/&γ;2
11.54	Single	8UNZ	Epinephrine	8UNZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
11.54	Single	8W88	SEP-363856	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2
11.54	Single	8WC8	ZH8651	8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
11.54	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
11.54	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
11.54	Consensus	5ht1e_on	Orthosteric Ligand	7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2
11.54	Consensus	5ht2a_off	Orthosteric Ligand	6A94-5-HT_2A-Zotepine 6WH4-5-HT_2A-Methiothepin 7VOE-5-HT_2A-Aripiprazole 7VOD-5-HT_2A-Cariprazine 7WC8-5-HT_2A-Lumateperone 6A93-5-HT_2A-Risperidone
11.54	Consensus	alpha2b_on	Orthosteric Ligand	6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2
11.54	Consensus	at1_off	Orthosteric Ligand	4YAY-AT₁-ZD-7155 4ZUD-AT₁-Olmesartan
11.54	Consensus	d3_on	Orthosteric Ligand	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2 7CMV-D₃-PD128907-Gi1/&β;1/&γ;2 7CMU-D₃-Pramipexole-Gi1/&β;1/&γ;2
11.54	Consensus	dop_off_allo	Orthosteric Ligand	4N6H-δ-Naltrindole-Na
11.54	Consensus	ghrelin_off	Orthosteric Ligand	6KO5-Ghrelin-PubChem 57400002 7F83-Ghrelin-PF-05190457
11.54	Consensus	gi_class-f	Orthosteric Ligand	gi_frizzled
11.54	Consensus	gi_frizzled	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
11.54	Consensus	gi_melatonin	Orthosteric Ligand	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2 7DB6-MT₁-Ramelteon-Gi1/&β;1/&γ;2 7VH0-MT₂-Ramelteon-Gi1/&β;1/&γ;1
11.54	Consensus	gs_tar	Orthosteric Ligand	8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2 8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8WC8-TA1-ZH8651-chim(NtGi1-Gs)/&β;1/&γ;2
11.54	Consensus	hca_on	Orthosteric Ligand	hca2_on hca3_on
11.54	Consensus	hcar_on	Orthosteric Ligand	hca_on
11.54	Consensus	nop_off	Orthosteric Ligand	4EA3-NOP-PubChem 10296561 5DHG-NOP-PubChem 25001412 5DHH-NOP-SB-612111
11.43	Single	6M1I	PACAP	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
11.43	Single	6NIY	Adrenomedullin	6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
11.43	Single	6WIV	PubChem 52923113; PubChem 52924645	6WIV-GABA_B1, GABA_B2-PubChem 52923113; PubChem 52924645
11.43	Single	7AD3	Alpha-factor mating pheromone	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
11.43	Single	7FIN	Peptide-20; GGL	7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2
11.43	Single	7RYC	Oxytocin	7RYC-OT-Oxytocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
11.43	Single	8IHF	MK6892	8IHF-HCA₂-MK6892-Gi1/&β;1/&γ;2
11.43	Consensus	class-d_on	Orthosteric Ligand	ste2_on
11.43	Consensus	gi_class-d	Orthosteric Ligand	gi_ste
11.43	Consensus	gi_ste	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
11.43	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
11.36	Consensus	ct_on	Orthosteric Ligand	7TYL-CT-Amylin-Gs/&β;1/&γ;2 7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2
11.11	Single	1HZX	11-cis-Retinal	1HZX-Rhodopsin-11-cis-Retinal
11.11	Single	2VT4	Cyanopindolol	2VT4-β₁-Cyanopindolol
11.11	Single	2Y01	Dobutamine	2Y01-β₁-Dobutamine
11.11	Single	3NY8	ICI 118-551	3NY8-β₂-ICI 118-551
11.11	Single	3NYA	(S)-Alprenolol	3NYA-β₂-(S)-Alprenolol
11.11	Single	3ZPQ	4-(piperazin-1- yl)-1H-indole	3ZPQ-β₁-4-(piperazin-1- yl)-1H-indole-Na
11.11	Single	3ZPR	4-methyl-2-(piperazin-1-yl)	3ZPR-β₁-4-methyl-2-(piperazin-1-yl)-Na
11.11	Single	4EA3	PubChem 10296561	4EA3-NOP-PubChem 10296561
11.11	Single	4EJ4	Naltrindole	4EJ4-δ-Naltrindole
11.11	Single	4GBR	(S)-Carazolol	4GBR-β₂-(S)-Carazolol
11.11	Single	4QKX	PubChem 76210628	4QKX-β₂-PubChem 76210628
11.11	Single	4ZUD	Olmesartan	4ZUD-AT₁-Olmesartan
11.11	Single	5DHG	PubChem 25001412	5DHG-NOP-PubChem 25001412
11.11	Single	5JQH	(S)-Carazolol	5JQH-β₂-(S)-Carazolol
11.11	Single	5OLZ	PubChem 135566609	5OLZ-A_2A-PubChem 135566609-Na
11.11	Single	5OM1	PubChem 135566609	5OM1-A_2A-PubChem 135566609-Na
11.11	Single	6DRZ	Methysergide	6DRZ-5-HT_2B-Methysergide
11.11	Single	6H7M	Salbutamol	6H7M-β₁-Salbutamol
11.11	Single	6K42	Dexmedetomidine	6K42-α_2b-Dexmedetomidine-Gi1/&β;1/&γ;2
11.11	Single	6PS0	(S)-Carazolol	6PS0-β₂-(S)-Carazolol
11.11	Single	6PS2	(S)-Alprenolol	6PS2-β₂-(S)-Alprenolol
11.11	Single	6TOT	Lemborexant	6TOT-OX₁-Lemborexant
11.11	Single	6UUN	Adrenomedullin	6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
11.11	Single	7BTS	L-Epinephrine	7BTS-β₁-L-Epinephrine
11.11	Single	7BU6	L-Norepinephrine	7BU6-β₁-L-Norepinephrine
11.11	Single	7E32	Serotonin	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
11.11	Single	7F83	PF-05190457	7F83-Ghrelin-PF-05190457
11.11	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
11.11	Single	7T2G	Mitragynine pseudoindoxyl	7T2G-μ-Mitragynine pseudoindoxyl-Gi1/&β;1/&γ;2
11.11	Single	7TRY	Urocortin	7TRY-CRF₂-Urocortin-chim(NtGi1-G11)/&β;1/&γ;2
11.11	Single	7UL4	Alvimopan	7UL4-μ-Alvimopan
11.11	Single	7UM5	5-CT	7UM5-5-HT_5A-5-CT-chim(NtGi1-Go)/&β;1/&γ;2
11.11	Single	7VKT	LTB4	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
11.11	Single	7WC7	Lisuride	7WC7-5-HT_2A-Lisuride
11.11	Single	7XTC	5-CT	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
11.11	Single	7YAC	Paltusotine	7YAC-SST2-Paltusotine-Gi1/&β;1/&γ;2
11.11	Single	7YK7	DC591053	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2
11.11	Single	8DZS	GR89,696	8DZS-κ-GR89,696-chim(NtGi2-Gz)/&β;1/&γ;2
11.11	Single	8GE3	Epinephrine	8GE3-β₂-Epinephrine-Gs/&β;1/&γ;2
11.11	Single	8GEB	Epinephrine	8GEB-β₂-Epinephrine-Gs/&β;1/&γ;2
11.11	Single	8GEE	Epinephrine	8GEE-β₂-Epinephrine-Gs/&β;1/&γ;2
11.11	Single	8GFW	Epinephrine	8GFW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
11.11	Single	8GFX	Epinephrine	8GFX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
11.11	Single	8GFY	Epinephrine	8GFY-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
11.11	Single	8GFZ	Epinephrine	8GFZ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
11.11	Single	8GG0	Epinephrine	8GG0-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
11.11	Single	8GG1	Epinephrine	8GG1-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
11.11	Single	8GG2	Epinephrine	8GG2-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
11.11	Single	8GG6	Epinephrine	8GG6-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
11.11	Single	8GGJ	Epinephrine	8GGJ-β₂-Epinephrine
11.11	Single	8GGN	Epinephrine	8GGN-β₂-Epinephrine
11.11	Single	8GGO	Epinephrine	8GGO-β₂-Epinephrine
11.11	Single	8GGU	Epinephrine	8GGU-β₂-Epinephrine
11.11	Single	8I7V	Acipimox	8I7V-HCA₂-Acipimox-Gi1/&β;1/&γ;2
11.11	Single	8I7W	GSK256073	8I7W-HCA₂-GSK256073-Gi1/&β;1/&γ;2
11.11	Single	8IRT	Rotigotine	8IRT-D₃-Rotigotine-Gi1/&β;1/&γ;2
11.11	Single	8J18	(3R)-3-hydroxydodecanoic acid	8J18-GPR84-(3R)-3-hydroxydodecanoic acid-Gi1/&β;1/&γ;2
11.11	Single	8JJO	Alprenolol	8JJO-β₂-Alprenolol
11.11	Single	8K5D	GSK256073	8K5D-HCA₂-GSK256073
11.11	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
11.11	Single	8UNM	Epinephrine	8UNM-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
11.11	Single	8UNN	Epinephrine	8UNN-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
11.11	Single	8UNP	Epinephrine	8UNP-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
11.11	Single	8UO4	Epinephrine	8UO4-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
11.11	Single	8W87	METH	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2
11.11	Single	8W8A	RO5256390	8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2
11.11	Single	8X63	Mepyramine	8X63-H₁-Mepyramine
11.11	Single	8X64	Desloratadine	8X64-H₁-Desloratadine
11.11	Consensus	5ht1a_on	Orthosteric Ligand	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2 7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
11.11	Consensus	5ht1d_on	Orthosteric Ligand	7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2
11.11	Consensus	5ht2_off	Orthosteric Ligand	5ht2a_off 5ht2b_off 5ht2c_off
11.11	Consensus	5ht7_on	Orthosteric Ligand	7XTC-5-HT₇-5-CT-Gs/&β;1/&γ;2
11.11	Consensus	adrenergic_on	Orthosteric Ligand	beta_on alpha_on
11.11	Consensus	alpha2_on	Orthosteric Ligand	alpha2a_on alpha2b_on
11.11	Consensus	alpha_on	Orthosteric Ligand	alpha1_on alpha2_on
11.11	Consensus	blt1_on	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
11.11	Consensus	blt_on	Orthosteric Ligand	blt1_on
11.11	Consensus	d5_on	Orthosteric Ligand	8IRV-D₅-Rotigotine-chim(NtGi1-Gs)/&β;1/&γ;2
11.11	Consensus	dop_off	Orthosteric Ligand	4EJ4-δ-Naltrindole
11.11	Consensus	dopamine_on	Orthosteric Ligand	d3_on d2_on d5_on d1_on
11.11	Consensus	gi_5ht	Orthosteric Ligand	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2 8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2 7E32-5-HT_1D-Serotonin-Gi1/&β;1/&γ;2 7E33-5-HT_1E-BRL-54443-Gi1/&β;1/&γ;2 7EXD-5-HT_1F-Lasmiditan-Gi1/&β;1/&γ;2 7XTA-5-HT₄-Serotonin-Gi1/&β;1/&γ;2 7X5H-5-HT_5A-5-CT-Gi1/&β;1/&γ;2 7E2Z-5-HT_1A-Aripiprazole-Gi1/&β;1/&γ;2 8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
11.11	Consensus	gi_leukotriene	Orthosteric Ligand	7VKT-BLT₁-LTB4-Gi1/&β;1/&γ;2
11.11	Consensus	hcar_off	Orthosteric Ligand	succinate_off
11.11	Consensus	leuko_on	Orthosteric Ligand	blt_on
11.11	Consensus	prostanoid_off	Orthosteric Ligand	ep_off tp_off dp_off
11.11	Consensus	succinate_off	Orthosteric Ligand	6RNK-Succinate-NF-56-EJ40 6Z10-Succinate-PubChem 154585554
11.11	Consensus	tar_on	Orthosteric Ligand	ta1_on
10.81	Single	6P9Y	PACAP	6P9Y-PAC₁-PACAP-Gs/&β;1/&γ;2
10.81	Consensus	ctlike_on	Orthosteric Ligand	6E3Y-CT Like-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1 6UUN-CT Like (AM1)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP2
10.81	Consensus	ghrh_on	Orthosteric Ligand	7CZ5-GHRH-Somatoliberin-Gs/&β;1/&γ;2
10.81	Consensus	glp1_on_allo	Orthosteric Ligand	6VCB-GLP-1-GLP-1-LSN3160440-Gs/&β;1/&γ;2
10.71	Single	2RH1	(S)-Carazolol	2RH1-β₂-(S)-Carazolol
10.71	Single	2Y00	Dobutamine	2Y00-β₁-Dobutamine
10.71	Single	2YCW	(S)-Carazolol	2YCW-β₁-(S)-Carazolol
10.71	Single	5D6L	(S)-Carazolol	5D6L-β₂-(S)-Carazolol
10.71	Single	5WIU	Nemonapride	5WIU-D₄-Nemonapride
10.71	Single	5WIV	Nemonapride	5WIV-D₄-Nemonapride-Na
10.71	Single	5X7D	(S)-Carazolol	5X7D-β₂-(S)-Carazolol-PubChem 129318963
10.71	Single	5ZK3	Quinuclidinyl benzilate hydrobromide	5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
10.71	Single	6LUQ	Haloperidol	6LUQ-D₂-Haloperidol
10.71	Single	6M9T	Misoprostol-FA	6M9T-EP₃-Misoprostol-FA
10.71	Single	6PS6	Timolol	6PS6-β₂-Timolol
10.71	Single	7BZ2	Arformoterol	7BZ2-β₂-Arformoterol-Gs/&β;1/&γ;2
10.71	Single	7EUO	fMLF	7EUO-FPR1-ALX-fMLF-Gi1/&β;1/&γ;2
10.71	Single	7M3J	NPS-2143; PO4	7M3J-CaS-NPS-2143; PO4
10.71	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
10.71	Single	7SIN	NPS-2143	7SIN-CaS-NPS-2143
10.71	Single	7VOE	Aripiprazole	7VOE-5-HT_2A-Aripiprazole
10.71	Single	8GDA	L902688	8GDA-EP₄-L902688-Gs/&β;1/&γ;2
10.71	Single	8GDC	PGE2	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
10.71	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
10.71	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
10.71	Consensus	5ht1_on	Orthosteric Ligand	5ht1a_on 5ht1d_on 5ht1e_on 5ht1f_on 5ht1b_on
10.71	Consensus	alpha2a_on	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
10.71	Consensus	amine_off	Orthosteric Ligand	adrenergic_off histamine_off muscarinic_off 5ht_off dopamine_off
10.71	Consensus	beta2_off	Orthosteric Ligand	6PS2-β₂-(S)-Alprenolol 6PS3-β₂-(S)-Carvedilol 6PS5-β₂-(S)-Propranolol 6PS6-β₂-Timolol 2RH1-β₂-(S)-Carazolol 6PS4-β₂-ICI 118-551 3NY9-β₂-PubChem 913103
10.71	Consensus	beta_off	Orthosteric Ligand	beta1_off beta2_off
10.71	Consensus	beta_on	Orthosteric Ligand	beta1_on beta2_on beta3_on
10.71	Consensus	d4_off	Orthosteric Ligand	5WIU-D₄-Nemonapride
10.71	Consensus	d4_off_allo	Orthosteric Ligand	5WIV-D₄-Nemonapride-Na
10.71	Consensus	ep3_on	Orthosteric Ligand	8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2
10.71	Consensus	go_amine	Orthosteric Ligand	go_adrenergic go_muscarinic go_5ht
10.71	Consensus	rxfp4_on	Orthosteric Ligand	7YK7-RXFP4-DC591053-Gi2/&β;1/&γ;2 7YJ4-RXFP4-INSL5-Gi2/&β;1/&γ;2 7YK6-RXFP4-PubChem 138319674-Gi2/&β;1/&γ;2
10.71	Consensus	ta1_on	Orthosteric Ligand	8W87-TA1-METH-chim(NtGi1L-Gs)/&β;1/&γ;2 8W89-TA1-PEA-chim(NtGi1L-Gs)/&β;1/&γ;2 8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2 8W8A-TA1-RO5256390-chim(NtGi1L-Gs)/&β;1/&γ;2 8W88-TA1-SEP-363856-Gs/&β;1/&γ;2 8JLN-TA1-T1AM-Gs/&β;1/&γ;2 8JLO-TA1-Ulotaront-Gs/&β;1/&γ;2 8JLR-TA1-A77636-chim(NtGi1-Gs)/&β;1/&γ;2 8JSO-TA1-AMPH-chim(NtGi1-Gs)/&β;1/&γ;2 8JLQ-TA1-Fenoldopam-Gs/&β;1/&γ;2 8WCA-TA1-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
10.64	Consensus	gs_calcitonin	Orthosteric Ligand	gs_ct gs_cgrp
10.64	Consensus	gs_ct	Orthosteric Ligand	7TYN-CT-Calcitonin-1-Gs/&β;1/&γ;2 6NIY-CT-Adrenomedullin-Gs/&β;1/&γ;2 8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2 7TYL-CT-Amylin-Gs/&β;1/&γ;2 8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
10.53	Single	7VQX	PACAP27	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
10.53	Consensus	glp2_on	Orthosteric Ligand	7D68-GLP-2-GLP-2-Gs/&β;1/&γ;2
10.53	Consensus	ste2_on	Orthosteric Ligand	7AD3-STE2-Alpha-factor mating pheromone-Gi1/STE4/&γ;2
10.34	Single	3UON	Quinuclidinyl benzilate hydrobromide	3UON-M₂-Quinuclidinyl benzilate hydrobromide
10.34	Single	5D5A	(S)-Carazolol	5D5A-β₂-(S)-Carazolol
10.34	Single	5D5B	(S)-Carazolol	5D5B-β₂-(S)-Carazolol
10.34	Single	5ZHP	PubChem 134828589	5ZHP-M₃-PubChem 134828589
10.34	Single	5ZKB	AF-DX 384	5ZKB-M₂-AF-DX 384
10.34	Single	7EW4	CYM5541	7EW4-S1P₃-CYM5541-Gi1/&β;1/&γ;2
10.34	Single	7VGY	2-Iodomelatonin	7VGY-MT₁-2-Iodomelatonin-Gi1/&β;1/&γ;2
10.34	Single	7W6P	W96	7W6P-α_2a-W96-Go/&β;1/&γ;2
10.34	Single	7W7E	W58	7W7E-α_2a-W58-Go/&β;1/&γ;2
10.34	Single	7XTQ	R399	7XTQ-GPBA-R399-Gs/&β;1/&γ;2
10.34	Single	8EF5	Fentanyl	8EF5-μ-Fentanyl-Gi1/&β;1/&γ;2
10.34	Single	8IRR	Rotigotine	8IRR-D₁-Rotigotine-Gs/&β;1/&γ;2
10.34	Single	8JD0	J9R	8JD0-mGlu2; mGlu3-Glutamate-J9R
10.34	Single	8JLP	Ralmitaront	8JLP-TA1-Ralmitaront-Gs/&β;1/&γ;2
10.34	Single	8JXW	VUF6884	8JXW-H₄-VUF6884-Gi1/&β;1/&γ;2
10.34	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
10.34	Single	8X79	MRE-269	8X79-I2-MRE-269-Gs/&β;1/&γ;2
10.34	Single	8XJM	Latanoprost	8XJM-FP-alpha-Latanoprost-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
10.34	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
10.34	Consensus	5ht_off	Orthosteric Ligand	5ht2_off 5ht5_off 5ht1_off
10.34	Consensus	beta1_off	Orthosteric Ligand	2VT4-β₁-Cyanopindolol 2YCZ-β₁-Iodocyanopindolol
10.34	Consensus	gi_amine	Orthosteric Ligand	gi_5ht gi_adrenergic gi_dopamine gi_muscarinic gi_histamine
10.34	Consensus	go_adrenergic	Orthosteric Ligand	7EJ0-α_2a-L-Norepinephrine-Go/&β;1/&γ;2 7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2 7W7E-α_2a-W58-Go/&β;1/&γ;2 7W6P-α_2a-W96-Go/&β;1/&γ;2 6K41-α_2b-Dexmedetomidine-Go/&β;1/&γ;2 7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2 7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
10.34	Consensus	h1_off	Orthosteric Ligand	3RZE-H₁-Cidoxepin 8X5Y-H₁-Astemizole 8X63-H₁-Mepyramine 8X64-H₁-Desloratadine
10.34	Consensus	histamine_off	Orthosteric Ligand	h1_off
10.34	Consensus	npy_off	Orthosteric Ligand	npy2_off npy1_off
10.34	Consensus	s1p2_on	Orthosteric Ligand	7T6B-S1P₂-S1P-chim(NtGi1L-G13)/&β;1/&γ;2
10.26	Single	6UUS	Adrenomedullin	6UUS-CT Like (AM2)-Adrenomedullin-Gs/&β;1/&γ;2; RAMP3
10.26	Consensus	glp1_on	Orthosteric Ligand	6X18-GLP-1-GLP-1-Gs/&β;1/&γ;2 6X19-GLP-1-CHU-128-Gs/&β;1/&γ;2 6X1A-GLP-1-Danuglipron-Gs/&β;1/&γ;2 7S1M-GLP-1-Ex4-D-Ala-Gs/&β;1/&γ;2 7LLL-GLP-1-Exendin-4-Gs/&β;1/&γ;2 6B3J-GLP-1-Exendin-P5-Gs/&β;1/&γ;2 8JIP-GLP-1-MEDI0382-chim(NtGi1-Gs)/&β;1/&γ;2 7VBI-GLP-1-Non-Acylated Tirzepatide-Gs/&β;1/&γ;2 6XOX-GLP-1-Orforglipron-chim(NtGi1-Gs)/&β;1/&γ;2 8JIS-GLP-1-Peptide-15-chim(NtGi1-Gs)/&β;1/&γ;2 7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2 7VBH-GLP-1-Peptide-20-Gs/&β;1/&γ;2 7C2E-GLP-1-PubChem 149050799-Gs/&β;1/&γ;2 8JIR-GLP-1-SAR425899-chim(NtGi1-Gs)/&β;1/&γ;2 7KI0-GLP-1-Semaglutide-Gs/&β;1/&γ;2 7KI1-GLP-1-Taspoglutide-Gs/&β;1/&γ;2 7FIM-GLP-1-Tirzepatide-Gs/&β;1/&γ;2
10.26	Consensus	secretin_on	Orthosteric Ligand	6WZG-Secretin-Secretin-Gs/&β;1/&γ;2
10.26	Consensus	vpac2_on	Orthosteric Ligand	7VQX-VPAC₁-PACAP27-Gs/&β;1/&γ;2
10.00	Single	3D4S	Timolol Maleate	3D4S-β₂-Timolol Maleate
10.00	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
10.00	Single	6AK3	Dinoprostone IPGE2	6AK3-EP₃-Dinoprostone IPGE2
10.00	Single	6CM4	Risperidone	6CM4-D₂-Risperidone
10.00	Single	6H7N	(S)-Xamoterol	6H7N-β₁-(S)-Xamoterol
10.00	Single	6ZG4	HTL0009936	6ZG4-M₁-HTL0009936
10.00	Single	7D7M	Dinoprostone	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1
10.00	Single	7JNI	Olodanrigan	7JNI-AT₂-Olodanrigan
10.00	Single	7TYL	Amylin	7TYL-CT-Amylin-Gs/&β;1/&γ;2
10.00	Single	7W0L	PubChem 122701908	7W0L-Apelin-PubChem 122701908-Gi1/&β;1/&γ;2
10.00	Single	8E9W	2-Deoxycytidine	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
10.00	Single	8GCP	PGE2	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2
10.00	Single	8IJD	MK6892	8IJD-HCA₂-MK6892-Gi1/&β;1/&γ;2
10.00	Single	8JZ7	MK6892	8JZ7-HCA₂-MK6892-Gi1/&β;1/&γ;2
10.00	Consensus	at2_off	Orthosteric Ligand	7JNI-AT₂-Olodanrigan
10.00	Consensus	beta1_on	Orthosteric Ligand	7JJO-β₁-Isoprenaline-Gs/&β;1/&γ;2 8DCR-β₁-Dobutamine-Gs/&β;1/&γ;2
10.00	Consensus	d2_off	Orthosteric Ligand	6CM4-D₂-Risperidone 6LUQ-D₂-Haloperidol 7DFP-D₂-Spiperone
10.00	Consensus	ep_on	Orthosteric Ligand	ep4_on ep2_on ep3_on
10.00	Consensus	gip_on	Orthosteric Ligand	7DTY-GIP-GIP-Gs/&β;1/&γ;2 7VAB-GIP-Non-Acylated Tirzepatide-chim(NtGi1-Gs)/&β;1/&γ;2 7FIN-GIP-Peptide-20; GGL-Gs/&β;1/&γ;2 7FIY-GIP-Tirzepatide-Gs/&β;1/&γ;2
10.00	Consensus	gs_bileacid	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
10.00	Consensus	gs_steroid	Orthosteric Ligand	gs_bileacid
9.76	Single	7TYH	Calcitonin-1	7TYH-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
9.68	Single	4OR2	FITM	4OR2-mGlu1; mGlu1-FITM
9.68	Single	6BQH	Ritanserin	6BQH-5-HT_2C-Ritanserin
9.68	Single	7CX4	Evatanepag	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2
9.68	Single	7SK7	CCX662	7SK7-ACKR3-CXCL12-CCX662
9.68	Single	7XK2	MK6892	7XK2-HCA₂-MK6892-Gi1/&β;1/&γ;2
9.68	Single	8E9Y	PubChem 446603	8E9Y-M₃-PubChem 446603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
9.68	Single	8JD3	HZR; PEF	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
9.68	Single	8K2X	CXCL10	8K2X-CXCR3-CXCL10-Gi1/&β;1/&γ;2
9.68	Single	8XJO	U46619	8XJO-TP-U46619-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
9.68	Consensus	5ht2c_off	Orthosteric Ligand	6BQH-5-HT_2C-Ritanserin
9.68	Consensus	adgrg2_on	Orthosteric Ligand	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2 7WUI-ADGRG2-IP15-chim(NtGi1-Gs)/&β;1/&γ;2
9.68	Consensus	bileacid_on	Orthosteric Ligand	7CFN-GPBA-INT-777-Gs/&β;1/&γ;2 7CFM-GPBA-P395-Gs/&β;1/&γ;2 7XTQ-GPBA-R399-Gs/&β;1/&γ;2
9.68	Consensus	ep2_on	Orthosteric Ligand	7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
9.68	Consensus	ep4_on	Orthosteric Ligand	7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2 8GDA-EP₄-L902688-Gs/&β;1/&γ;2
9.68	Consensus	fpa_on	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
9.68	Consensus	steroid_on	Orthosteric Ligand	bileacid_on
9.52	Single	5MZP	Caffeine	5MZP-A_2A-Caffeine-Na
9.52	Single	8WCB	Cyclohexylammonium ion	8WCB-TA1-Cyclohexylammonium ion-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
9.52	Consensus	pth1_on	Orthosteric Ligand	8FLQ-PTH1-PTH-Gs/&β;1/&γ;2 8FLR-PTH1-PTHrP(1-36)-Gs/&β;1/&γ;2 7Y36-PTH1-Teriparatide-Gs/&β;1/&γ;2 7Y35-PTH1-Abaloparatide-Gs/&β;1/&γ;2 8FLU-PTH1-Long-acting PTH-Gs/&β;1/&γ;2 6NBF-PTH1-Long-acting PTH analog-Gs/&β;1/&γ;2 7VVM-PTH1-PTH-Gs/&β;1/&γ;2
9.52	Consensus	vip-pacap_on	Orthosteric Ligand	vpac1_on vpac2_on pca1_on
9.38	Single	5EE7	MK0893	5EE7-Glucagon-MK0893
9.38	Single	7SK9	CCX662	7SK9-ACKR3-CCX662
9.38	Single	8IQ4	Carboprost	8IQ4-FP-alpha-Carboprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
9.38	Single	8IUM	Tafluprost acid	8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
9.30	Single	7TYY	Calcitonin-1	7TYY-CT (AMY2)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP2
9.09	Single	7CX3	Taprenepag	7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2
9.09	Single	7RTB	Peptide-19	7RTB-GLP-1-Peptide-19-Gs/&β;1/&γ;2
9.09	Single	8HQM	NPGLY	8HQM-GPR132-NPGLY-Gi1/&β;1/&γ;2
9.09	Consensus	gabab_off	Other Ligand	7C7S-GABA_B1, GABA_B2-CGP54626 7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid 6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
8.89	Single	8F2A	Pramlintide analogue san385	8F2A-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
8.70	Single	6OY9	All-trans-retinal	6OY9-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
8.70	Single	6TQ9	SB-408124	6TQ9-OX₁-SB-408124
8.70	Single	6XBM	25(S)-Epoxycholesterol	6XBM-SMO-25(S)-Epoxycholesterol-Gi1/&β;1/&γ;2
8.70	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
8.70	Single	7VDM	Substance P	7VDM-MRGPRX2-Substance P-Gi1/&β;1/&γ;2
8.70	Single	8DPH	Lorcaserin	8DPH-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8.70	Single	8HVI	NOX-6-7	8HVI-GPR132-NOX-6-7-Gi1/&β;1/&γ;2
8.70	Single	8IWM	2-Phenylethylamine	8IWM-TAAR9-2-Phenylethylamine
8.51	Single	7TYO	Calcitonin	7TYO-CT-Calcitonin-Gs/&β;1/&γ;2
8.51	Consensus	glu_on	Orthosteric Ligand	6LMK-Glucagon-Glucagon-Gs/&β;1/&γ;2 6WPW-Glucagon-Glucagon derivative ZP3780-Gs/&β;1/&γ;2 8JIT-Glucagon-MEDI0382-Gs/&β;1/&γ;2 8JIQ-Glucagon-Peptide-15-Gs/&β;1/&γ;2 7V35-Glucagon-Peptide-20-Gs/&β;1/&γ;2 8JIU-Glucagon-SAR425899-Gs/&β;1/&γ;2 6WHC-Glucagon-Glu16 analog of GCG-Gs/&β;1/&γ;2
8.33	Single	2ZIY	11-cis-Retinal	2ZIY-Rhodopsin-11-cis-Retinal
8.33	Single	3OE8	IT1t	3OE8-CXCR4-IT1t
8.33	Single	3UZA	GTPL9236	3UZA-A_2A-GTPL9236
8.33	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
8.33	Single	6FUF	All-trans-retinal	6FUF-Rhodopsin-All-trans-retinal-Go/&β;1/&γ;2
8.33	Single	7MT8	All-trans-retinal	7MT8-Rhodopsin-All-trans-retinal-GRK1
8.33	Single	7MT9	All-trans-retinal	7MT9-Rhodopsin-All-trans-retinal-GRK1
8.33	Single	7MTA	All-trans-retinal	7MTA-Rhodopsin-All-trans-retinal-GRK1
8.33	Single	7S8O	(R)-Zinc-3573	7S8O-MRGPRX2-(R)-Zinc-3573-Gi1/&β;1/&γ;2
8.33	Single	8DPI	Lorcaserin	8DPI-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8.33	Single	8F76	-	8F76-OR51E2-Gs/&β;1/&γ;2
8.33	Single	8GGR	Epinephrine	8GGR-β₂-Epinephrine
8.33	Single	8GGZ	Epinephrine	8GGZ-β₂-Epinephrine
8.33	Single	8IW7	2-Phenylethylamine	8IW7-TAAR9-2-Phenylethylamine-chim(NtGi1-Gs)/&β;1/&γ;2
8.33	Single	8J6Q	Beta-hydroxybutyrate	8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
8.33	Single	8JGB	Conorfamide-Tx2	8JGB-MRGPRX1-Conorfamide-Tx2-Gi1/&β;1/&γ;2
8.33	Single	8JXT	Histamine	8JXT-H₄-Histamine-PO4-Gi1/&β;1/&γ;2
8.33	Single	8POK	Histamine	8POK-H₂-Histamine-Gs/&β;1/&γ;2
8.33	Single	8WC9	ZH8651	8WC9-TA1-ZH8651-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8.33	Consensus	smo_off_allo	Orthosteric Ligand	6D32-SMO-Cyclopamine-Cyclopamine
8.11	Single	7WBJ	PACAP27	7WBJ-VPAC₁-PACAP27-Gs/&β;1/&γ;2
8.11	Consensus	crf2_on	Orthosteric Ligand	7TS0-CRF₂-Urocortin-chim(NtGi1L-Go)/&β;1/&γ;2
8.11	Consensus	vpac1_on	Orthosteric Ligand	8E3Y-VPAC₁-PACAP27-Gs/&β;1/&γ;2 8E3Z-VPAC₁-VIP-Gs/&β;1/&γ;2 6VN7-VPAC₁-PACAP-Gs/&β;1/&γ;2
8.00	Single	1U19	11-cis-Retinal	1U19-Rhodopsin-11-cis-Retinal
8.00	Single	2G87	All-trans-retinal	2G87-Rhodopsin-All-trans-retinal
8.00	Single	2I35	11-cis-Retinal	2I35-Rhodopsin-11-cis-Retinal
8.00	Single	5OLV	LUAA41063	5OLV-A_2A-LUAA41063-Na
8.00	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
8.00	Single	7DFL	Histamine	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
8.00	Single	7E2Y	Serotonin	7E2Y-5-HT_1A-Serotonin-Gi1/&β;1/&γ;2
8.00	Single	7EJK	Oxymetazoline	7EJK-α_2a-Oxymetazoline-Go/&β;1/&γ;2
8.00	Single	7S8N	(R)-Zinc-3573	7S8N-MRGPRX2-(R)-Zinc-3573-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8.00	Single	7V68	Iperoxo	7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
8.00	Single	7XKF	Betahydroxyandrosterone	7XKF-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
8.00	Single	7YFC	Histamine	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
8.00	Single	8DPF	Lorcaserin	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
8.00	Single	8F0J	Pramlintide analogue san45	8F0J-CT-Pramlintide analogue san45-Gs/&β;1/&γ;2
8.00	Single	8GEI	Epinephrine	8GEI-β₂-Epinephrine-Gs/&β;1/&γ;2
8.00	Single	8GGC	Epinephrine	8GGC-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
8.00	Single	8GGE	Epinephrine	8GGE-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
8.00	Single	8GGS	Epinephrine	8GGS-β₂-Epinephrine
8.00	Single	8GGY	Epinephrine	8GGY-β₂-Epinephrine
8.00	Single	8H2G	Niacin	8H2G-HCA₂-Niacin-Gi1/&β;1/&γ;2
8.00	Single	8IHI	Acifran	8IHI-HCA₂-Acifran-Gi1/&β;1/&γ;2
8.00	Single	8ITF	DMCHA	8ITF-TAAR9-DMCHA-chim(NtGi1-Gs)/&β;1/&γ;2
8.00	Single	8IY9	Niacin	8IY9-HCA₂-Niacin-Go/&β;1/&γ;2
8.00	Single	8K5B	Niacin	8K5B-HCA₂-Niacin
8.00	Single	8UNV	Epinephrine	8UNV-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
8.00	Single	8W8B	SEP-363856	8W8B-5-HT_1A-SEP-363856-Gi1/&β;1/&γ;2
8.00	Single	8WC3	SEP-363856	8WC3-TA1-SEP-363856-chim(NtGi1-Gs)/&β;1/&γ;2
8.00	Consensus	gq_histamine	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
8.00	Consensus	h1_on	Orthosteric Ligand	7DFL-H₁-Histamine-chim(NtGi1L-Gq)/&β;1/&γ;2
8.00	Consensus	smo_on_allo	Orthosteric Ligand	6XBL-SMO-SAG-Cholesterol-Gi1/&β;1/&γ;2
7.69	Single	2PED	9-cis-Retinal	2PED-Rhodopsin-9-cis-Retinal
7.69	Single	2Z73	11-cis-Retinal	2Z73-Rhodopsin-11-cis-Retinal
7.69	Single	3AYN	9-cis-Retinal	3AYN-Rhodopsin-9-cis-Retinal
7.69	Single	6AKY	Maraviroc	6AKY-CCR5-Maraviroc
7.69	Single	6KUY	PubChem 145704643	6KUY-α_2a-PubChem 145704643
7.69	Single	6OYA	All-trans-retinal	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
7.69	Single	6RNK	NF-56-EJ40	6RNK-Succinate-NF-56-EJ40
7.69	Single	7LJD	Dopamine	7LJD-D₁-Dopamine-Mevidalen-Gs/&β;1/&γ;1
7.69	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
7.69	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
7.69	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
7.69	Single	7T8X	Acetylcholine	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
7.69	Single	7T90	Acetylcholine	7T90-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
7.69	Single	7YM8	Oxymetazoline	7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2
7.69	Single	7YMH	Norepinephrine	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2
7.69	Single	8DWH	Compound-16	8DWH-MRGPRX1-Compound-16-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7.69	Single	8GEC	Epinephrine	8GEC-β₂-Epinephrine-Gs/&β;1/&γ;2
7.69	Single	8GED	Epinephrine	8GED-β₂-Epinephrine-Gs/&β;1/&γ;2
7.69	Single	8GEF	Epinephrine	8GEF-β₂-Epinephrine-Gs/&β;1/&γ;2
7.69	Single	8GG7	Epinephrine	8GG7-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
7.69	Single	8GG9	Epinephrine	8GG9-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
7.69	Single	8GGA	Epinephrine	8GGA-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
7.69	Single	8GGV	Epinephrine	8GGV-β₂-Epinephrine
7.69	Single	8GGW	Epinephrine	8GGW-β₂-Epinephrine
7.69	Single	8GGX	Epinephrine	8GGX-β₂-Epinephrine
7.69	Single	8GH0	Epinephrine	8GH0-β₂-Epinephrine
7.69	Single	8HOC	Imetit	8HOC-H₄-Imetit-Gi1/&β;1/&γ;2
7.69	Single	8U4P	AMD3100	8U4P-CXCR4-AMD3100-Cholesterol-Gi1/&β;1/&γ;2
7.69	Single	8U8F	PML	8U8F-GPR3-PML-Gs/&β;1/&γ;2
7.69	Single	8UNL	Epinephrine	8UNL-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
7.69	Single	8UNO	Epinephrine	8UNO-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
7.69	Single	8UNT	Epinephrine	8UNT-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
7.69	Single	8UNU	Epinephrine	8UNU-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
7.69	Single	8UNW	Epinephrine	8UNW-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
7.69	Single	8UO1	Epinephrine	8UO1-β₂-Epinephrine-GTP; Mg-Gs/&β;1/&γ;2
7.69	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
7.69	Consensus	5ht2_on	Orthosteric Ligand	5ht2a_on 5ht2c_on
7.69	Consensus	5ht2c_on	Orthosteric Ligand	8DPF-5-HT_2C-Lorcaserin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7.69	Consensus	alpha1_on	Orthosteric Ligand	alpha1a_on
7.69	Consensus	alpha1a_on	Orthosteric Ligand	7YMH-Alpha1A-Norepinephrine-chim(Gs-CtGq)/&β;1/&γ;2 7YM8-Alpha1A-Oxymetazoline-chim(Gs-CtGq)/&β;1/&γ;2 8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8THL-Alpha1A-Epinephrine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7.69	Consensus	gi_histamine	Orthosteric Ligand	8HN8-H₄-Histamine-Gi1/&β;1/&γ;2 8HOC-H₄-Imetit-Gi1/&β;1/&γ;2
7.69	Consensus	gs_histamine	Orthosteric Ligand	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7.69	Consensus	gt_class-a	Orthosteric Ligand	gt_opsin
7.69	Consensus	gt_opsin	Orthosteric Ligand	gt_sensory
7.69	Consensus	gt_sensory	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
7.69	Consensus	h4_on	Orthosteric Ligand	7YFC-H₄-Histamine-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7.69	Consensus	m2_on	Orthosteric Ligand	7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
7.69	Consensus	mglu_on	Other Ligand	mglu2_on mglu4_on
7.50	Single	7TYW	Calcitonin-1	7TYW-CT (AMY1)-Calcitonin-1-Gs/&β;1/&γ;2; RAMP1
7.50	Consensus	calcitonin_on	Orthosteric Ligand	ct_on ctlike_on
7.50	Consensus	crf1_on	Orthosteric Ligand	6P9X-CRF₁-Corticoliberin-Gs/&β;1/&γ;2
7.41	Single	4MQT	Iperoxo	4MQT-M₂-Iperoxo-LY2119620
7.41	Single	6A94	Zotepine	6A94-5-HT_2A-Zotepine
7.41	Single	6WH4	Methiothepin	6WH4-5-HT_2A-Methiothepin
7.41	Single	6WJC	Atropine	6WJC-M₁-Atropine-Muscarinic toxin 7
7.41	Single	6ZFZ	77-LH-28-1	6ZFZ-M₁-77-LH-28-1
7.41	Single	6ZG9	GSK1034702	6ZG9-M₁-GSK1034702
7.41	Single	7DHI	Salbutamol	7DHI-β₂-Salbutamol-Gs/&β;1/&γ;2
7.41	Single	7EJ8	Brimonidine	7EJ8-α_2a-Brimonidine-Go/&β;1/&γ;2
7.41	Single	7EJA	Dexmedetomidine	7EJA-α_2a-Dexmedetomidine-Go/&β;1/&γ;2
7.41	Single	7T94	Acetylcholine	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2
7.41	Single	7TRS	Acetylcholine	7TRS-M₄-Acetylcholine-Gi1/&β;1/&γ;2
7.41	Single	7VVO	PTH	7VVO-PTH1-PTH-Gs/&β;1/&γ;2
7.41	Single	7ZBE	11-cis-Retinal	7ZBE-Rhodopsin-11-cis-Retinal
7.41	Single	8DPG	Psilocin	8DPG-5-HT_2C-Psilocin-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7.41	Single	8GE1	Epinephrine	8GE1-β₂-Epinephrine-Gs/&β;1/&γ;2
7.41	Single	8GE4	Epinephrine	8GE4-β₂-Epinephrine-Gs/&β;1/&γ;2
7.41	Single	8GE6	Epinephrine	8GE6-β₂-Epinephrine-Gs/&β;1/&γ;2
7.41	Single	8GE7	Epinephrine	8GE7-β₂-Epinephrine-Gs/&β;1/&γ;2
7.41	Single	8GE8	Epinephrine	8GE8-β₂-Epinephrine-Gs/&β;1/&γ;2
7.41	Single	8GE9	Epinephrine	8GE9-β₂-Epinephrine-Gs/&β;1/&γ;2
7.41	Single	8GFV	Epinephrine	8GFV-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
7.41	Single	8GG3	Epinephrine	8GG3-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
7.41	Single	8GG4	Epinephrine	8GG4-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
7.41	Single	8GG8	Epinephrine	8GG8-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
7.41	Single	8GGI	Epinephrine	8GGI-β₂-Epinephrine
7.41	Single	8H4L	Doconexent	8H4L-FFA4-Doconexent-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
7.41	Single	8HNM	VUF11222	8HNM-CXCR3-VUF11222-Gi1/&β;1/&γ;2
7.41	Single	8JLN	T1AM	8JLN-TA1-T1AM-Gs/&β;1/&γ;2
7.41	Single	8JSP	Ulotaront	8JSP-5-HT_1A-Ulotaront-Gi1/&β;1/&γ;2
7.41	Single	8K2W	AMG487	8K2W-CXCR3-AMG487
7.41	Single	8THK	A61603	8THK-Alpha1A-A61603-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7.41	Single	8UNQ	Epinephrine	8UNQ-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
7.41	Single	8UNR	Epinephrine	8UNR-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
7.41	Single	8UNS	Epinephrine	8UNS-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
7.41	Consensus	5ht2a_on	Orthosteric Ligand	7RAN-5-HT_2A-PubChem 164575847-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
7.41	Consensus	m1_off_allo	Orthosteric Ligand	6WJC-M₁-Atropine-Muscarinic toxin 7
7.32	Single	7TYF	Amylin	7TYF-CT (AMY1)-Amylin-Gs/&β;1/&γ;2; RAMP1
7.32	Single	7TYX	Amylin	7TYX-CT (AMY2)-Amylin-Gs/&β;1/&γ;2; RAMP2
7.14	Single	4DAJ	Tiotropium	4DAJ-M₃-Tiotropium
7.14	Single	4MQS	Iperoxo	4MQS-M₂-Iperoxo
7.14	Single	4U14	Tiotropium	4U14-M₃-Tiotropium
7.14	Single	4U16	N-Methyl Scopolamine	4U16-M₃-N-Methyl Scopolamine
7.14	Single	5DSG	Tiotropium	5DSG-M₄-Tiotropium
7.14	Single	5YC8	N-Methyl Scopolamine	5YC8-M₂-N-Methyl Scopolamine
7.14	Single	5ZK8	N-Methyl Scopolamine	5ZK8-M₂-N-Methyl Scopolamine
7.14	Single	5ZKC	N-Methyl Scopolamine	5ZKC-M₂-N-Methyl Scopolamine
7.14	Single	6GPS	MK0812	6GPS-CCR2-MK0812
7.14	Single	6IIV	Daltroban	6IIV-TP-Daltroban
7.14	Single	7CFM	P395	7CFM-GPBA-P395-Gs/&β;1/&γ;2
7.14	Single	7E9G	JNJ-40411813	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
7.14	Single	7EPF	NAM597	7EPF-mGlu2; mGlu2-NAM597
7.14	Single	7TRP	Iperoxo	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2
7.14	Single	7WC8	Lumateperone	7WC8-5-HT_2A-Lumateperone
7.14	Single	8JLJ	T1AM	8JLJ-TA1-T1AM-chim(NtGi1-Gs)/&β;1/&γ;2
7.14	Single	8KFY	ZK-756326	8KFY-CCR8-ZK-756326-Gi1/&β;1/&γ;2
7.14	Single	8WC7	ZH8667	8WC7-TA1-ZH8667-chim(NtGi1-Gs)/&β;1/&γ;2
7.14	Single	8XJL	PGF2-alpha	8XJL-FP-alpha-PGF2-alpha-chim(NtGi2-Gs-CtGq)/&β;1/&γ;2
7.14	Consensus	amine_on	Orthosteric Ligand	adrenergic_on histamine_on muscarinic_on tar_on 5ht_on dopamine_on
7.14	Consensus	go_muscarinic	Orthosteric Ligand	8E9X-M₄-2-Deoxycytidine-chim(NtGi1-Go)/&β;1/&γ;2 7T8X-M₂-Acetylcholine-chim(NtGi1-Go)/&β;1/&γ;2
7.14	Consensus	gq_amine	Orthosteric Ligand	gq_muscarinic gq_histamine
7.14	Consensus	histamine_on	Orthosteric Ligand	h1_on h4_on
7.14	Consensus	m2_on_allo	Orthosteric Ligand	7T94-M₂-Acetylcholine-PubChem 57664406-chim(NtGi1-Go)/&β;1/&γ;2 6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
7.14	Consensus	m4_off	Orthosteric Ligand	5DSG-M₄-Tiotropium
7.14	Consensus	m4_on_allo	Orthosteric Ligand	7TRP-M₄-Iperoxo-LY2033298-Gi1/&β;1/&γ;2 7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2 7V68-M₄-Iperoxo-PubChem 57664406-Gi1/&β;1/&γ;2
7.14	Consensus	muscarinic_on	Orthosteric Ligand	m2_on m3_on m4_on m1_on
7.14	Consensus	tp_off	Orthosteric Ligand	6IIV-TP-Daltroban 6IIU-TP-Ramatroban
6.98	Single	7TZF	Amylin	7TZF-CT (AMY3)-Amylin-Gs/&β;1/&γ;2; RAMP3
6.90	Single	5YHL	PubChem 135121352	5YHL-EP₄-PubChem 135121352
6.90	Single	5YWY	ONO-AE3-208	5YWY-EP₄-ONO-AE3-208
6.90	Single	6GPX	MK0812	6GPX-CCR2-MK0812
6.90	Single	6OIK	Iperoxo	6OIK-M₂-Iperoxo-LY2119620-chim(NtGi1-Go)/&β;1/&γ;2
6.90	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
6.90	Single	7TRK	Iperoxo	7TRK-M₄-Iperoxo-Gi1/&β;1/&γ;2
6.90	Single	8E9Z	Iperoxo	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
6.90	Single	8EA0	Iperoxo	8EA0-M₃-Iperoxo
6.90	Single	8GD9	Rivenprost	8GD9-EP₄-Rivenprost-Gs/&β;1/&γ;2
6.90	Single	8HNL	PS372424	8HNL-CXCR3-PS372424-Gi1/&β;1/&γ;2
6.90	Consensus	ep4_off	Orthosteric Ligand	5YWY-EP₄-ONO-AE3-208 5YHL-EP₄-PubChem 135121352
6.90	Consensus	ep_off	Orthosteric Ligand	ep4_off
6.90	Consensus	gq_muscarinic	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
6.90	Consensus	gs_muscarinic	Orthosteric Ligand	8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
6.90	Consensus	m1_on	Orthosteric Ligand	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
6.90	Consensus	m2_off	Orthosteric Ligand	5ZKB-M₂-AF-DX 384 5ZKC-M₂-N-Methyl Scopolamine 5ZK3-M₂-Quinuclidinyl benzilate hydrobromide
6.90	Consensus	m3_on	Orthosteric Ligand	8E9Z-M₃-Iperoxo-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2 8E9W-M₃-2-Deoxycytidine-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
6.82	Single	9AUC	Calcitonin gene-related peptide-1	9AUC-CT-Calcitonin gene-related peptide-1-Gs/&β;1/&γ;2; RAMP1
6.67	Single	4U15	Tiotropium	4U15-M₃-Tiotropium
6.67	Single	5V54	Methiothepin	5V54-5-HT_1B-Methiothepin
6.67	Single	6OIJ	Iperoxo	6OIJ-M₁-Iperoxo-chim(NtGi1L-G11)/&β;1/&γ;2
6.67	Single	6OL9	Tiotropium	6OL9-M₅-Tiotropium
6.67	Single	7TRQ	Iperoxo	7TRQ-M₄-Iperoxo-VU0467154-Gi1/&β;1/&γ;2
6.67	Single	8GDB	PGE2	8GDB-EP₄-PGE2-Gs/&β;1/&γ;2
6.67	Single	8JXX	Clobenpropit	8JXX-H₄-Clobenpropit-Gi1/&β;1/&γ;2
6.67	Consensus	5ht1_off	Orthosteric Ligand	5ht1b_off
6.67	Consensus	5ht1b_off	Orthosteric Ligand	5V54-5-HT_1B-Methiothepin
6.67	Consensus	angiotensin_off	Orthosteric Ligand	at1_off at2_off
6.67	Consensus	m3_off	Orthosteric Ligand	4U15-M₃-Tiotropium 4U16-M₃-N-Methyl Scopolamine 5ZHP-M₃-PubChem 134828589
6.67	Consensus	m5_off	Orthosteric Ligand	6OL9-M₅-Tiotropium
6.67	Consensus	muscarinic_off	Orthosteric Ligand	m2_off m3_off m4_off m5_off m1_off
6.45	Single	5CXV	Tiotropium	5CXV-M₁-Tiotropium
6.45	Single	5X33	BIIL260	5X33-BLT₁-BIIL260
6.45	Single	6IIU	Ramatroban	6IIU-TP-Ramatroban
6.45	Consensus	gi_prostanoid	Orthosteric Ligand	8GCP-EP₄-PGE2-Gi1/&β;1/&γ;2 8GDC-EP₃-PGE2-Gi1/&β;1/&γ;2 8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
6.45	Consensus	m1_off	Orthosteric Ligand	5CXV-M₁-Tiotropium
6.45	Consensus	prostanoid_on	Orthosteric Ligand	ep_on fpa_on
6.25	Single	7CX2	PGE2	7CX2-EP₂-PGE2-Gs/&β;1/&γ;2
6.25	Single	7SK8	CCX662	7SK8-ACKR3-CXCL12-CCX662
6.25	Consensus	gs_prostanoid	Orthosteric Ligand	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 8IUM-FP-alpha-Tafluprost acid-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2 7CX2-EP₂-PGE2-Gs/&β;1/&γ;2 7CX3-EP₂-Taprenepag-Gs/&β;1/&γ;2 7D7M-EP₄-Dinoprostone-Gs/&β;1/&γ;1 7CX4-EP₂-Evatanepag-Gs/&β;1/&γ;2 8IUL-FP-alpha-Latanoprost-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
6.12	Single	8F2B	Pramlintide analogue san45	8F2B-CT (AMY3)-Pramlintide analogue san45-Gs/&β;1/&γ;2; RAMP3
6.06	Single	8XZF	WN561	8XZF-Apelin-WN561-Gi1/&β;1/&γ;2
5.41	Consensus	pca1_on	Orthosteric Ligand	6M1I-PAC₁-PACAP-Gs/&β;1/&γ;2
5.26	Single	6D32	Cyclopamine	6D32-SMO-Cyclopamine-Cyclopamine
5.26	Single	6D35	Cholesterol	6D35-SMO-Cholesterol
5.26	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
5.26	Single	6N51	Quisqualate	6N51-mGlu5; mGlu5-Quisqualate
5.26	Single	6UO8	SKF97541	6UO8-GABA_B1, GABA_B2-SKF97541-GS39783
5.26	Single	6UO9	SKF97541	6UO9-GABA_B1, GABA_B2-SKF97541
5.26	Single	6W2X	PubChem 5311042	6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
5.26	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
5.26	Single	6W2Y	PubChem 5311042	6W2Y-GABAB1; GABAB1-PubChem 5311042-PubChem 23727970
5.26	Single	7C7Q	Baclofen	7C7Q-GABA_B1, GABA_B2-Baclofen-PubChem 7023848
5.26	Single	7C7S	CGP54626	7C7S-GABA_B1, GABA_B2-CGP54626
5.26	Single	7CUM	CGP54626	7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid
5.26	Single	7DD5	Ca3	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
5.26	Single	7DD5	Ca	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
5.26	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
5.26	Single	7DD5	Ca; Ca; Tryptophan; NPS-2143	7DD5-CaS-Ca-Ca; Ca; Tryptophan; NPS-2143
5.26	Single	7DGE	Quisqualate	7DGE-mGlu1; mGlu1-Quisqualate
5.26	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
5.26	Single	7DTT	Ca	7DTT-CaS-Ca-Ca
5.26	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
5.26	Single	7DTU	Tryptophan	7DTU-CaS-Tryptophan
5.26	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
5.26	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
5.26	Single	7DTV	Ca	7DTV-CaS-Ca-Ca; Tryptophan
5.26	Single	7DTV	Ca; Tryptophan	7DTV-CaS-Ca-Ca; Tryptophan
5.26	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.26	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.26	Single	7E6T	Ca	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.26	Single	7E6T	Ca; Ca; Cyclomethyltryptophan; PO4	7E6T-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.26	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
5.26	Single	7E9G	Eglumetad	7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
5.26	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
5.26	Single	7E9H	Phosphoserine	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2
5.26	Single	7EB2	Baclofen	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
5.26	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
5.26	Single	7EPB	Eglumetad	7EPB-mGlu2; mGlu2-Eglumetad
5.26	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
5.26	Single	7FD8	Quisqualate	7FD8-mGlu5; mGlu5-Quisqualate
5.26	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
5.26	Single	7FD9	LY341495	7FD9-mGlu5; mGlu5-LY341495
5.26	Single	7FIH	hCG	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
5.26	Single	7FII	hCG	7FII-LH-hCG-6fuf
5.26	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
5.26	Single	7M3E	Ca; Ca; Tryptophan; NPS-2143; PO4	7M3E-CaS-Ca; Ca; Tryptophan; NPS-2143; PO4
5.26	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
5.26	Single	7M3F	Ca; Ca; Tryptophan; Cinacalcet; PO4	7M3F-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4
5.26	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
5.26	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
5.26	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
5.26	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
5.26	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
5.26	Single	7MTQ	LY341495	7MTQ-mGlu2; mGlu2-LY341495
5.26	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
5.26	Single	7MTR	Glutamate	7MTR-mGlu2; mGlu2-Glutamate-ADX55164
5.26	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
5.26	Single	7MTS	Glutamate	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2
5.26	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
5.26	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
5.26	Single	7SIL	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
5.26	Single	7SIL	Ca	7SIL-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4
5.26	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.26	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.26	Single	7SIM	Ca	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.26	Single	7SIM	Ca; Ca; Cyclomethyltryptophan; PO4	7SIM-CaS-Ca-Ca; Ca; Cyclomethyltryptophan; PO4
5.26	Single	7T9N	M22 Fab	7T9N-TSH-M22 Fab-PubChem 644078-Gs/&β;1/&γ;2
5.26	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
5.26	Single	7WI6	LY341495	7WI6-mGlu3; mGlu3-LY341495
5.26	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
5.26	Single	7WI8	LY341495	7WI8-mGlu3; mGlu3-LY341495
5.26	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
5.26	Single	7WIH	LY2794193	7WIH-mGlu3; mGlu3-LY2794193
5.26	Single	7XW6	M22 Fab	7XW6-TSH-M22 Fab-ML109-Gs/&β;1/&γ;2
5.26	Single	7XW7	K1-70	7XW7-TSH-K1-70
5.26	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
5.26	Single	8JCU	LY341495	8JCU-mGlu2; mGlu3-LY341495
5.26	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
5.26	Single	8JCV	LY341495	8JCV-mGlu2; mGlu3-LY341495
5.26	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
5.26	Single	8JCW	LY341495	8JCW-mGlu2; mGlu3-LY341495
5.26	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
5.26	Single	8JCX	LY341495	8JCX-mGlu2; mGlu3-LY341495
5.26	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
5.26	Single	8JCY	LY341495	8JCY-mGlu2; mGlu3-LY341495
5.26	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
5.26	Single	8JCZ	LY341495	8JCZ-mGlu2; mGlu3-LY341495
5.26	Single	8JD0	Glutamate	8JD0-mGlu2; mGlu3-Glutamate-J9R
5.26	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
5.26	Single	8JD1	Glutamate	8JD1-mGlu2; mGlu3-Glutamate
5.26	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
5.26	Single	8JD2	Glutamate	8JD2-mGlu2; mGlu3-Glutamate
5.26	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
5.26	Single	8JD3	Glutamate	8JD3-mGlu2; mGlu3-Glutamate-HZR; PEF-Gi1/&β;1/&γ;2
5.26	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
5.26	Single	8JD4	Glutamate	8JD4-mGlu2; mGlu4-Glutamate
5.26	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
5.26	Single	8JD5	Glutamate	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
5.26	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
5.26	Single	8JD6	Phosphoserine	8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
5.26	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
5.26	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
5.26	Single	8SZF	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZF-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW
5.26	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
5.26	Single	8SZG	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZG-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-chim(NtGi1-Gq)/&β;1/&γ;2
5.26	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
5.26	Single	8SZH	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZH-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi1/&β;1/&γ;2
5.26	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
5.26	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
5.26	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
5.26	Single	8T7H	Quisqualate	8T7H-mGlu5; mGlu5-Quisqualate
5.26	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
5.26	Single	8T8M	Quisqualate	8T8M-mGlu5; mGlu5-Quisqualate
5.26	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
5.26	Single	8TAO	Quisqualate	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
5.26	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
5.26	Single	8WPG	Tryptophan; Cinacalcet; PO4; Ca	8WPG-CaS-Tryptophan; Cinacalcet; PO4; Ca
5.26	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
5.26	Single	8WPU	Tryptophan; Cinacalcet; PO4; Ca	8WPU-CaS-Tryptophan; Cinacalcet; PO4; Ca-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
5.26	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.26	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.26	Single	9AXF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.26	Single	9AXF	Ca	9AXF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
5.26	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
5.26	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
5.26	Consensus	class-c_off	Orthosteric Ligand	gabab_off mglu_off
5.26	Consensus	class-c_off	Orthosteric Ligand	gabab_off mglu_off
5.26	Consensus	class-c_on	Orthosteric Ligand	gabab_on mglu_on
5.26	Consensus	class-c_on	Orthosteric Ligand	gabab_on mglu_on
5.26	Consensus	fsh_on_allo	Orthosteric Ligand	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
5.26	Consensus	gabab_off	Orthosteric Ligand	7C7S-GABA_B1, GABA_B2-CGP54626 7CUM-GABA_B1, GABA_B2-CGP54626-Phospholipid 6W2X-GABA_B1, GABA_B2-PubChem 5311042-PubChem 23727970
5.26	Consensus	gabab_on	Orthosteric Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
5.26	Consensus	gi_class-c	Orthosteric Ligand	gi_mglu gi_gaba
5.26	Consensus	gi_class-c	Orthosteric Ligand	gi_mglu gi_gaba
5.26	Consensus	gi_gaba	Orthosteric Ligand	7EB2-GABA_B1, GABA_B2-Baclofen-rac-BHFF-Gi1/&β;1/&γ;2
5.26	Consensus	gi_mglu	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
5.26	Consensus	gi_mglu	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
5.26	Consensus	gphr_on	Orthosteric Ligand	lh_on tsh_on
5.26	Consensus	gs_gphr	Orthosteric Ligand	7T9I-TSH-TSH-Gs/&β;1/&γ;2 7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
5.26	Consensus	gs_protein	Orthosteric Ligand	gs_gphr
5.26	Consensus	lh_on	Orthosteric Ligand	7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
5.26	Consensus	lh_on_allo	Orthosteric Ligand	7FIH-LH-hCG-Org43553-chim(NtGi1-Gs)/&β;1/&γ;2
5.26	Consensus	mglu2_off	Orthosteric Ligand	7MTQ-mGlu2; mGlu2-LY341495
5.26	Consensus	mglu2_off	Orthosteric Ligand	7MTQ-mGlu2; mGlu2-LY341495
5.26	Consensus	mglu2_on	Orthosteric Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
5.26	Consensus	mglu2_on	Orthosteric Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
5.26	Consensus	mglu3_off	Orthosteric Ligand	7WI8-mGlu3; mGlu3-LY341495 7WIH-mGlu3; mGlu3-LY2794193
5.26	Consensus	mglu3_off	Orthosteric Ligand	7WI8-mGlu3; mGlu3-LY341495 7WIH-mGlu3; mGlu3-LY2794193
5.26	Consensus	mglu4_on	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
5.26	Consensus	mglu4_on	Orthosteric Ligand	7E9H-mGlu4; mGlu4-Phosphoserine-Gi3/&β;1/&γ;2 8JD6-mGlu4; mGlu4-Phosphoserine-N-(3-chlorophenyl)pyridine-2-carboxamide-Gi3/&β;1/&γ;2
5.26	Consensus	mglu5_off	Orthosteric Ligand	7FD9-mGlu5; mGlu5-LY341495
5.26	Consensus	mglu5_off	Orthosteric Ligand	7FD9-mGlu5; mGlu5-LY341495
5.26	Consensus	mglu_off	Orthosteric Ligand	mglu2_off mglu3_off mglu5_off
5.26	Consensus	mglu_off	Orthosteric Ligand	mglu2_off mglu3_off mglu5_off
5.26	Consensus	mglu_on	Orthosteric Ligand	mglu2_on mglu4_on
5.26	Consensus	mglu_on	Orthosteric Ligand	mglu2_on mglu4_on
5.26	Consensus	smo_off_allo	Other Ligand	6D32-SMO-Cyclopamine-Cyclopamine
5.26	Consensus	tsh_on	Orthosteric Ligand	7T9I-TSH-TSH-Gs/&β;1/&γ;2
5.26	Consensus	tsh_on_allo	Orthosteric Ligand	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
5.00	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
5.00	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
5.00	Single	7DD6	Ca	7DD6-CaS-Ca-Ca; Ca; Tryptophan
5.00	Single	7DD6	Ca; Ca; Tryptophan	7DD6-CaS-Ca-Ca; Ca; Tryptophan
5.00	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
5.00	Single	7DD7	Ca	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
5.00	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
5.00	Single	7DD7	Ca; Ca; Tryptophan; Evocalcet	7DD7-CaS-Ca-Ca; Ca; Tryptophan; Evocalcet
5.00	Single	9AYF	Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
5.00	Single	9AYF	Ca	9AYF-CaS-Ca-Ca; Ca; Ca; Cyclomethyltryptophan; 9IG; PO4-Gi1/&β;1/&γ;2
4.76	Single	7KNU	Calcitonin gene-related peptide-1	7KNU-CT Like-Calcitonin gene-related peptide-1-RAMP1
4.76	Single	7T9M	CS-17 Antibody	7T9M-TSH-CS-17 Antibody
4.76	Single	7TYI	Amylin	7TYI-CT-Amylin-Gs/&β;1/&γ;2
4.76	Single	8HS2	Fab046	8HS2-GPR20-Fab046
4.55	Single	4A4M	All-trans-retinal	4A4M-Rhodopsin-All-trans-retinal-Gt(CT)
4.55	Single	5EN0	All-trans-retinal	5EN0-Rhodopsin-All-trans-retinal-Gt(CT)
4.55	Single	6O3C	Cholesterol	6O3C-SMO-SAG21k-Cholesterol
4.55	Single	6W25	Ca	6W25-MC₄-SHU9119-Ca
4.55	Single	7FIG	hCG	7FIG-LH-hCG-chim(NtGi1L-Gs)/&β;1/&γ;2
4.55	Single	7UTZ	TR1402	7UTZ-TSH-TR1402-PubChem 644078-Gs/&β;1/&γ;2
4.55	Single	7XW5	TSH	7XW5-TSH-TSH-ML109-Gs/&β;1/&γ;2
4.55	Single	7ZI0	Cholesterol	7ZI0-SMO-SAG-Cholesterol
4.55	Single	8F0K	Pramlintide analogue san385	8F0K-CT (AMY3)-Pramlintide analogue san385-Gs/&β;1/&γ;2; RAMP3
4.55	Single	8TLM	Anti-murine CCR8 antibody	8TLM-CCR8-Anti-murine CCR8 antibody
4.55	Consensus	ccr8_off	Orthosteric Ligand	8TLM-CCR8-Anti-murine CCR8 antibody
4.35	Single	3PXO	All-trans-retinal	3PXO-Rhodopsin-All-trans-retinal
4.35	Single	5DYS	All-trans-retinal	5DYS-Rhodopsin-All-trans-retinal
4.35	Single	5L7D	Cholesterol	5L7D-SMO-Cholesterol
4.35	Single	7T9I	TSH	7T9I-TSH-TSH-Gs/&β;1/&γ;2
4.35	Single	7XKE	Betahydroxyandrosterone	7XKE-ADGRG2-Betahydroxyandrosterone-chim(NtGi1-Gs)/&β;1/&γ;2
4.35	Single	8GEJ	Epinephrine	8GEJ-β₂-Epinephrine-Gs/&β;1/&γ;2
4.35	Single	8HSC	Fab046	8HSC-GPR20-Fab046-Gi1/&β;1/&γ;2
4.35	Single	8I2G	Glycoprotein hormones alpha chain	8I2G-FSH-Glycoprotein hormones alpha chain-Compound 716340-Gs/&β;1/&γ;2
4.35	Single	8SZI	Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW	8SZI-CaS-Ca; Ca; Tryptophan; Cinacalcet; PO4; PCW-Gi3/&β;1/&γ;2
4.35	Consensus	class-c_on	Other Ligand	gabab_on mglu_on
4.17	Single	2HPY	All-trans-retinal	2HPY-Rhodopsin-All-trans-retinal
4.17	Single	7MTB	All-trans-retinal	7MTB-Rhodopsin-All-trans-retinal-GRK1
4.17	Single	7XKD	Betahydroxyandrosterone	7XKD-ADGRG2-Betahydroxyandrosterone-Gs/&β;1/&γ;2
4.17	Single	7Y14	Beta-alanine	7Y14-MRGPRD-Beta-alanine
4.17	Single	8WC5	Tetramethylammonium ion	8WC5-TA1-Tetramethylammonium ion-chim(NtGi1-Gs)/&β;1/&γ;2
4.17	Consensus	hca2_on_allo	Orthosteric Ligand	8J6P-HCA₂-Niacin-Compound 9n-Gi1/&β;1/&γ;2 8J6Q-HCA₂-Beta-hydroxybutyrate-Compound 9n-Gi1/&β;1/&γ;2
4.17	Consensus	sensory_on	Orthosteric Ligand	opsin_on
4.00	Single	3PQR	All-trans-retinal	3PQR-Rhodopsin-All-trans-retinal-Gt(CT)
4.00	Single	7Y12	Beta-alanine	7Y12-MRGPRD-Beta-alanine-Gi1/&β;1/&γ;2
4.00	Single	8IU2	Retinal	8IU2-Opsin1LW-Retinal-Gi1/&β;1/&γ;2
4.00	Consensus	gip_on_allo	Other Ligand	7RBT-GIP-Tirzepatide-PubChem 163183774-chim(NtGi1-Gs)/&β;1/&γ;2
4.00	Consensus	opsin_on	Orthosteric Ligand	6OYA-Rhodopsin-All-trans-retinal-Gt/&β;1/&γ;1
3.85	Single	3AYM	All-trans-retinal	3AYM-Rhodopsin-All-trans-retinal
3.85	Single	7YFD	Imetit	7YFD-H₄-Imetit-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
3.85	Single	8HN8	Histamine	8HN8-H₄-Histamine-Gi1/&β;1/&γ;2
3.85	Single	8IJA	Niacin	8IJA-HCA₂-Niacin-Gi1/&β;1/&γ;2
3.85	Single	8UNX	Epinephrine	8UNX-β₂-Epinephrine-GTP-Gs/&β;1/&γ;2
3.85	Single	8X2K	5YM	8X2K-GPR3-5YM-chim(NtGi1-Gs)/&β;1/&γ;2
3.70	Single	4XNV	BPTU	4XNV-P2Y₁-BPTU
3.70	Single	7DHR	Isoprenaline	7DHR-β₂-Isoprenaline-Gs/&β;1/&γ;2
3.70	Single	7WV9	ZCZ011	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
3.70	Single	8G94	CD69	8G94-S1P₁-CD69-Gi1/&β;1/&γ;2
3.70	Single	8GEA	Epinephrine	8GEA-β₂-Epinephrine-Gs/&β;1/&γ;2
3.70	Consensus	cb1_on_allo	Other Ligand	7WV9-CB₁-PubMed 104895-ZCZ011-Gi2/&β;1/&γ;2
3.57	Single	6FFI	MMPEP	6FFI-mGlu₅-MMPEP
3.57	Single	7M3G	Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4	7M3G-CaS-Ca; Ca; Tryptophan; Evocalcet; Etelcalcetide; PO4
3.57	Single	8GCM	L902688	8GCM-EP₄-L902688-Gi1/&β;1/&γ;2
3.57	Single	8IYX	YL-365	8IYX-GPR34-YL-365
3.45	Single	6FFH	Fenobam	6FFH-mGlu₅-Fenobam
3.45	Single	6WHA	DB13948	6WHA-5-HT_2A-DB13948-chim(NtGi2L-Gs-CtGq)/&β;1/&γ;2
3.33	Single	5CGC	HTL14242	5CGC-mGlu₅-HTL14242
3.33	Single	5T1A	PubChem 68764898; PubChem 12093170	5T1A-CCR2-PubChem 68764898; PubChem 12093170
3.33	Consensus	ccr2_off_allo	Other Ligand	5T1A-CCR2-PubChem 68764898; PubChem 12093170 6GPX-CCR2-MK0812
3.23	Single	4OO9	Mavoglurant	4OO9-mGlu₅-Mavoglurant
3.23	Single	7EPE	NAM563	7EPE-mGlu-NAM563
3.23	Single	7P2L	4YI	7P2L-mGlu₅-4YI
3.23	Single	8IUK	PGF2-alpha	8IUK-FP-alpha-PGF2-alpha-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
3.23	Single	8JD5	BQI; HZE; PEF	8JD5-mGlu2; mGlu4-Glutamate-BQI; HZE; PEF-Gi1/&β;1/&γ;2
3.23	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
3.23	Single	8TAO	CDPPB	8TAO-mGlu5; mGlu5-Quisqualate-CDPPB
3.23	Consensus	mglu2_on	Other Ligand	7MTS-mGlu2; mGlu2-Glutamate-ADX55164-Gi1/&β;1/&γ;2 7E9G-mGlu2; mGlu2-Eglumetad-JNJ-40411813-Gi1/&β;1/&γ;2
3.12	Single	8T6J	CDPPB	8T6J-mGlu5; mGlu5-CDPPB
3.03	Single	5CGD	HTL14242	5CGD-mGlu₅-HTL14242
2.78	Single	7SHE	PI; PE	7SHE-GPR158-PI; PE

Consensus Members
	Id	Members
	8U26	8U26-NK₁-Protachykinin-1-Gs/&β;1/&γ;2
	7XWO	7XWO-NK₂-Neurokinin-A-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2
	7P00	7P00-NK₁-Substance P-chim(NtGi1-Gs-CtGq)/&β;1/&γ;2

Net Summary
I_min	3.07333
Number of Linked Nodes	866
Number of Links	1061
Number of Hubs	158
Number of Links mediated by Hubs	607
Number of Communities	22
Number of Nodes involved in Communities	223
Number of Links involved in Communities	336

Path Summary
Number Of Nodes in MetaPath	84
Number Of Links MetaPath	83
Number of Shortest Paths	2654031
Length Of Smallest Path	3
Average Path Length	36.5884
Length of Longest Path	64
Minimum Path Strength	0.46
Average Path Strength	6.43427
Maximum Path Strength	20.035
Minimum Path Correlation	0.7
Average Path Correlation	0.978148
Maximum Path Correlation	1
Minimum % Of Corr. Nodes	1.75439
Average % Of Corr. Nodes	31.6375
Maximum % Of Corr. Nodes	100
Minimum Path Hubs %	0
Average Path Hubs %	43.7383
Maximum Path Hubs %	100

Details about the values in these tables can be found in the corresponding documentation page .

This network is also present in following consensuses:
	Id	Components
	gs_peptide	gs_cck gs_motilin gs_neuromedin gs_orexin gs_sst gs_tachykinin gs_trh gs_vasopressin-ot gs_bombesin gs_bradykinin gs_compl-peptide gs_endothelin gs_galanin gs_ghrelin gs_melanocortin

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Download gs_tachykinin.zip

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